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Articles published in Neurobiol Aging

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Single Articles


    June 2018
  1. POURBADIE HG, Sayyah M, Khoshkholgh-Sima B, Choopani S, et al
    Early minor stimulation of microglial TLR2 and TLR4 receptors attenuates Alzheimer's disease-related cognitive deficit in rats: behavioral, molecular, and electrophysiological evidence.
    Neurobiol Aging. 2018;70:203-216.
    PubMed     Text format     Abstract available


  2. BLECHINGBERG J, Poulsen ASA, Kjolby M, Monti G, et al
    An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor.
    Neurobiol Aging. 2018 Jun 28. pii: S0197-4580(18)30226.
    PubMed     Text format     Abstract available


  3. ASHTON NJ, Ide M, Scholl M, Blennow K, et al
    No association of salivary total tau concentration with Alzheimer's disease.
    Neurobiol Aging. 2018;70:125-127.
    PubMed     Text format     Abstract available


  4. RUTIGLIANO G, Stazi M, Arancio O, Watterson DM, et al
    An isoform-selective p38alpha mitogen-activated protein kinase inhibitor rescues early entorhinal cortex dysfunctions in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2018;70:86-91.
    PubMed     Text format     Abstract available


  5. BALDUCCI C, Santamaria G, La Vitola P, Brandi E, et al
    Doxycycline counteracts neuroinflammation restoring memory in Alzheimer's disease mouse models.
    Neurobiol Aging. 2018;70:128-139.
    PubMed     Text format     Abstract available


  6. HARRINGTON KD, Schembri A, Lim YY, Dang C, et al
    Estimates of age-related memory decline are inflated by unrecognized Alzheimer's disease.
    Neurobiol Aging. 2018;70:170-179.
    PubMed     Text format     Abstract available


  7. LOCKWOOD CT, Vaughn W, Duffy CJ
    Attentional ERPs distinguish aging and early Alzheimer's dementia.
    Neurobiol Aging. 2018;70:51-58.
    PubMed     Text format     Abstract available


  8. SCHULTZ N, Byman E, Wennstrom M
    Levels of retinal IAPP are altered in Alzheimer's disease patients and correlate with vascular changes and hippocampal IAPP levels.
    Neurobiol Aging. 2018;69:94-101.
    PubMed     Text format     Abstract available


  9. TABATABAEI-JAFARI H, Walsh E, Shaw ME, Cherbuin N, et al
    A simple and clinically relevant combination of neuroimaging and functional indexes for the identification of those at highest risk of Alzheimer's disease.
    Neurobiol Aging. 2018;69:102-110.
    PubMed     Text format     Abstract available


    May 2018
  10. FERREIRA D, Shams S, Cavallin L, Viitanen M, et al
    The contribution of small vessel disease to subtypes of Alzheimer's disease: a study on cerebrospinal fluid and imaging biomarkers.
    Neurobiol Aging. 2018;70:18-29.
    PubMed     Text format     Abstract available


  11. PONTIFEX M, Vauzour D, Minihane AM
    The effect of APOE genotype on Alzheimer's disease risk is influenced by sex and docosahexaenoic acid status.
    Neurobiol Aging. 2018;69:209-220.
    PubMed     Text format     Abstract available


  12. TAKKINEN JS, Lopez-Picon FR, Kirjavainen AK, Pihlaja R, et al
    [(18)F]FMPEP-d2 PET imaging shows age- and genotype-dependent impairments in the availability of cannabinoid receptor 1 in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2018;69:199-208.
    PubMed     Text format     Abstract available


  13. KOSTER RN, Jesper R, Bente P
    The total number of myelinated nerve fibers is reduced in corpus callosum in brains from patients with Alzheimer's disease.
    Neurobiol Aging. 2018;69:58-64.
    PubMed     Text format     Abstract available


  14. XIE T, Akbar S, Stathopoulou MG, Oster T, et al
    Epistatic interaction of apolipoprotein E and lipolysis-stimulated lipoprotein receptor genetic variants is associated with Alzheimer's disease.
    Neurobiol Aging. 2018 May 3. pii: S0197-4580(18)30147.
    PubMed     Text format     Abstract available


  15. VELAZQUEZ R, Tran A, Ishimwe E, Denner L, et al
    Corrigendum to "Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease" [Neurobiol. Aging 58 (2017) 1-13].
    Neurobiol Aging. 2018;65:235-238.
    PubMed     Text format    


    April 2018
  16. NING K, Chen B, Sun F, Hobel Z, et al
    Classifying Alzheimer's disease with brain imaging and genetic data using a neural network framework.
    Neurobiol Aging. 2018 Apr 24. pii: S0197-4580(18)30131.
    PubMed     Text format     Abstract available


  17. CHO H, Lee HS, Choi JY, Lee JH, et al
    Predicted sequence of cortical tau and amyloid-beta deposition in Alzheimer disease spectrum.
    Neurobiol Aging. 2018;68:76-84.
    PubMed     Text format     Abstract available


  18. FISHER DW, Bennett DA, Dong H
    Sexual dimorphism in predisposition to Alzheimer's disease.
    Neurobiol Aging. 2018 Apr 17. pii: S0197-4580(18)30126.
    PubMed     Text format     Abstract available


  19. ABDEL-HAFIZ L, Muller-Schiffmann A, Korth C, Fazari B, et al
    Abeta dimers induce behavioral and neurochemical deficits of relevance to early Alzheimer's disease.
    Neurobiol Aging. 2018;69:1-9.
    PubMed     Text format     Abstract available


  20. CACCAMO A, Belfiore R, Oddo S
    Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2018;68:59-67.
    PubMed     Text format     Abstract available


    March 2018
  21. DENGLER-CRISH CM, Ball HC, Lin L, Novak KM, et al
    Evidence of Wnt/beta-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease.
    Neurobiol Aging. 2018;67:148-158.
    PubMed     Text format     Abstract available


  22. CRISCUOLO C, Cerri E, Fabiani C, Capsoni S, et al
    The retina as a window to early dysfunctions of Alzheimer's disease following studies with a 5xFAD mouse model.
    Neurobiol Aging. 2018;67:181-188.
    PubMed     Text format     Abstract available


  23. VLASSENKO AG, Gordon BA, Goyal MS, Su Y, et al
    Aerobic glycolysis and tau deposition in preclinical Alzheimer's disease.
    Neurobiol Aging. 2018;67:95-98.
    PubMed     Text format     Abstract available


  24. DAUWAN M, Linszen MMJ, Lemstra AW, Scheltens P, et al
    EEG-based neurophysiological indicators of hallucinations in Alzheimer's disease: Comparison with dementia with Lewy bodies.
    Neurobiol Aging. 2018;67:75-83.
    PubMed     Text format     Abstract available


  25. WU C, Gong WG, Wang YJ, Sun JJ, et al
    Escitalopram alleviates stress-induced Alzheimer's disease-like tau pathologies and cognitive deficits by reducing hypothalamic-pituitary-adrenal axis reactivity and insulin/GSK-3beta signal pathway activity.
    Neurobiol Aging. 2018;67:137-147.
    PubMed     Text format     Abstract available


  26. DIAZ M, Fabelo N, Ferrer I, Marin R, et al
    "Lipid raft aging" in the human frontal cortex during nonpathological aging: gender influences and potential implications in Alzheimer's disease.
    Neurobiol Aging. 2018;67:42-52.
    PubMed     Text format     Abstract available


  27. WANG B, Bao S, Zhang Z, Zhou X, et al
    A rare variant in MLKL confers susceptibility to ApoE varepsilon4-negative Alzheimer's disease in Hong Kong Chinese population.
    Neurobiol Aging. 2018 Mar 10. pii: S0197-4580(18)30084.
    PubMed     Text format     Abstract available


  28. RUSSO R, Cattaneo F, Lippiello P, Cristiano C, et al
    Motor coordination and synaptic plasticity deficits are associated with increased cerebellar activity of NADPH oxidase, CAMKII, and PKC at preplaque stage in the TgCRND8 mouse model of Alzheimer's disease.
    Neurobiol Aging. 2018 Mar 5. pii: S0197-4580(18)30069.
    PubMed     Text format     Abstract available


  29. RAEFSKY SM, Furman R, Milne G, Pollock E, et al
    Deuterated polyunsaturated fatty acids reduce brain lipid peroxidation and hippocampal amyloid beta-peptide levels, without discernable behavioral effects in an APP/PS1 mutant transgenic mouse model of Alzheimer's disease.
    Neurobiol Aging. 2018;66:165-176.
    PubMed     Text format     Abstract available


    February 2018
  30. JASWAL G, Swardfager W, Gao FQ, Nestor SM, et al
    Reduced substantia innominata volume mediates contributions of microvascular and macrovascular disease to cognitive deficits in Alzheimer's disease.
    Neurobiol Aging. 2018;66:23-31.
    PubMed     Text format     Abstract available


  31. PICARD C, Julien C, Frappier J, Miron J, et al
    Alterations in cholesterol metabolism-related genes in sporadic Alzheimer's disease.
    Neurobiol Aging. 2018 Feb 9. pii: S0197-4580(18)30033.
    PubMed     Text format     Abstract available


  32. PETOK JR, Myers CE, Pa J, Hobel Z, et al
    Impairment of memory generalization in preclinical autosomal dominant Alzheimer's disease mutation carriers.
    Neurobiol Aging. 2018;65:149-157.
    PubMed     Text format     Abstract available


  33. PELLEIEUX S, Picard C, Lamarre-Theroux L, Dea D, et al
    Isoprenoids and tau pathology in sporadic Alzheimer's disease.
    Neurobiol Aging. 2018;65:132-139.
    PubMed     Text format     Abstract available


  34. BUTLER T, Harvey P, Deshpande A, Tanzi E, et al
    Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease.
    Neurobiol Aging. 2018;65:201-205.
    PubMed     Text format     Abstract available


  35. SASSI C, Nalls MA, Ridge PG, Gibbs JR, et al
    Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.
    Neurobiol Aging. 2018 Feb 2. pii: S0197-4580(18)30023.
    PubMed     Text format     Abstract available


  36. AMTUL Z, Uhrig M, Wang L, Rozmahel RF, et al
    Corrigendum to "Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight" [Neurobiol. Aging 33 (2012) 831.e21-831.e31].
    Neurobiol Aging. 2018;62:247.
    PubMed     Text format    


    January 2018
  37. POULAKIS K, Pereira JB, Mecocci P, Vellas B, et al
    Heterogeneous patterns of brain atrophy in Alzheimer's disease.
    Neurobiol Aging. 2018;65:98-108.
    PubMed     Text format     Abstract available


  38. RAO S, Ghani M, Guo Z, Deming Y, et al
    An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk.
    Neurobiol Aging. 2018 Jan 3. pii: S0197-4580(17)30424.
    PubMed     Text format     Abstract available


  39. DICKS E, Tijms BM, Ten Kate M, Gouw AA, et al
    Gray matter network measures are associated with cognitive decline in mild cognitive impairment.
    Neurobiol Aging. 2018;61:198-206.
    PubMed     Text format     Abstract available


  40. ROLANDI E, Cavedo E, Pievani M, Galluzzi S, et al
    Association of postoperative delirium with markers of neurodegeneration and brain amyloidosis: a pilot study.
    Neurobiol Aging. 2018;61:93-101.
    PubMed     Text format     Abstract available


  41. HOEIJMAKERS L, Meerhoff GF, de Vries JW, Ruigrok SR, et al
    The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesis.
    Neurobiol Aging. 2018;61:112-123.
    PubMed     Text format     Abstract available


  42. ROSE C, Dorard E, Audrain M, Gorisse-Hussonnois L, et al
    Transient increase in sAPPalpha secretion in response to Abeta1-42 oligomers: an attempt of neuronal self-defense?
    Neurobiol Aging. 2018;61:23-35.
    PubMed     Text format     Abstract available


  43. VERFAILLIE SCJ, Slot RE, Tijms BM, Bouwman F, et al
    Thinner cortex in patients with subjective cognitive decline is associated with steeper decline of memory.
    Neurobiol Aging. 2018;61:238-244.
    PubMed     Text format     Abstract available


    December 2017
  44. LI J, Zhang X, Li A, Liu S, et al
    Polygenic risk for Alzheimer's disease influences precuneal volume in two independent general populations.
    Neurobiol Aging. 2017;64:116-122.
    PubMed     Text format     Abstract available


  45. BABILONI C, Del Percio C, Lizio R, Noce G, et al
    Abnormalities of resting-state functional cortical connectivity in patients with dementia due to Alzheimer's and Lewy body diseases: an EEG study.
    Neurobiol Aging. 2017;65:18-40.
    PubMed     Text format     Abstract available


  46. PARIZKOVA M, Lerch O, Moffat SD, Andel R, et al
    The effect of Alzheimer's disease on spatial navigation strategies.
    Neurobiol Aging. 2017;64:107-115.
    PubMed     Text format     Abstract available


  47. ENGELMAN CD, Darst BF, Bilgel M, Vasiljevic E, et al
    The effect of rare variants in TREM2 and PLD3 on longitudinal cognitive function in the Wisconsin Registry for Alzheimer's Prevention.
    Neurobiol Aging. 2017 Dec 29. pii: S0197-4580(17)30422.
    PubMed     Text format     Abstract available


  48. CANTERO JL, Atienza M, Sanchez-Juan P, Rodriguez-Rodriguez E, et al
    Cerebral changes and disrupted gray matter cortical networks in asymptomatic older adults at risk for Alzheimer's disease.
    Neurobiol Aging. 2017;64:58-67.
    PubMed     Text format     Abstract available


  49. BIGNANTE EA, Ponce NE, Heredia F, Musso J, et al
    APP/Go protein Gbetagamma-complex signaling mediates Abeta degeneration and cognitive impairment in Alzheimer's disease models.
    Neurobiol Aging. 2017;64:44-57.
    PubMed     Text format     Abstract available


  50. CRAMER PE, Gentzel RC, Tanis KQ, Vardigan J, et al
    Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease.
    Neurobiol Aging. 2017;64:92-106.
    PubMed     Text format     Abstract available


  51. SYAMA A, Sen S, Kota LN, Viswanath B, et al
    Mutation burden profile in familial Alzheimer's disease cases from India.
    Neurobiol Aging. 2017 Dec 12. pii: S0197-4580(17)30396.
    PubMed     Text format     Abstract available


  52. SACKMANN V, Ansell A, Sackmann C, Lund H, et al
    Anti-inflammatory (M2) macrophage media reduce transmission of oligomeric amyloid beta in differentiated SH-SY5Y cells.
    Neurobiol Aging. 2017;60:173-182.
    PubMed     Text format     Abstract available


  53. SUN M, Zhang H
    Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.
    Neurobiol Aging. 2017;60:129-140.
    PubMed     Text format     Abstract available


  54. HAYES JM, Tang L, Viviano RP, van Rooden S, et al
    Subjective memory complaints are associated with brain activation supporting successful memory encoding.
    Neurobiol Aging. 2017;60:71-80.
    PubMed     Text format     Abstract available


  55. TAMAGNINI F, Walsh DA, Brown JT, Bondulich MK, et al
    Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein.
    Neurobiol Aging. 2017;60:44-56.
    PubMed     Text format     Abstract available


    November 2017
  56. NG ASL, Ng EYL, Tan YJ, Kandiah N, et al
    Case-control analysis of leucine-rich repeat kinase 2 protective variants in Alzheimer's disease.
    Neurobiol Aging. 2017 Nov 27. pii: S0197-4580(17)30383.
    PubMed     Text format     Abstract available


  57. AKHTER R, Shao Y, Shaw M, Formica S, et al
    Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's disease.
    Neurobiol Aging. 2017;63:110-119.
    PubMed     Text format     Abstract available


  58. TAKATA K, Amamiya T, Mizoguchi H, Kawanishi S, et al
    Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Abeta accumulation through suppression of neuronal gamma-secretase activity and promotion of microglial amyloid-beta phagocytosis and ameliorates cognitive impairment i
    Neurobiol Aging. 2017;62:197-209.
    PubMed     Text format     Abstract available


  59. PHILLIPS JS, Da Re F, Dratch L, Xie SX, et al
    Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease.
    Neurobiol Aging. 2017;63:75-87.
    PubMed     Text format     Abstract available


  60. SMAILOVIC U, Koenig T, Kareholt I, Andersson T, et al
    Quantitative EEG power and synchronization correlate with Alzheimer's disease CSF biomarkers.
    Neurobiol Aging. 2017;63:88-95.
    PubMed     Text format     Abstract available


  61. JEAN-LOUIS T, Rockwell P, Figueiredo-Pereira ME
    Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by alpha- and beta-secretases: relevance to Alzheimer's disease.
    Neurobiol Aging. 2017;62:130-145.
    PubMed     Text format     Abstract available


  62. FIFORD CM, Ridgway GR, Cash DM, Modat M, et al
    Patterns of progressive atrophy vary with age in Alzheimer's disease patients.
    Neurobiol Aging. 2017;63:22-32.
    PubMed     Text format     Abstract available


  63. FESSEL J
    Alzheimer's disease combination treatment.
    Neurobiol Aging. 2017 Nov 8. pii: S0197-4580(17)30361.
    PubMed     Text format    


  64. WIRTH M, Bejanin A, La Joie R, Arenaza-Urquijo EM, et al
    Regional patterns of gray matter volume, hypometabolism, and beta-amyloid in groups at risk of Alzheimer's disease.
    Neurobiol Aging. 2017 Nov 7. pii: S0197-4580(17)30362.
    PubMed     Text format     Abstract available


  65. BRENOWITZ WD, Han F, Kukull WA, Nelson PT, et al
    Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults.
    Neurobiol Aging. 2017;62:64-71.
    PubMed     Text format     Abstract available


  66. MASTROENI D, Nolz J, Sekar S, Delvaux E, et al
    Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain.
    Neurobiol Aging. 2017;63:12-21.
    PubMed     Text format     Abstract available


  67. YANG S, Hilton S, Alves JN, Saksida LM, et al
    Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration.
    Neurobiol Aging. 2017;59:197-209.
    PubMed     Text format     Abstract available


  68. BYUN MS, Kim HJ, Yi D, Choi HJ, et al
    Differential effects of blood insulin and HbA1c on cerebral amyloid burden and neurodegeneration in nondiabetic cognitively normal older adults.
    Neurobiol Aging. 2017;59:15-21.
    PubMed     Text format     Abstract available


  69. ARENAZA-URQUIJO EM, Bejanin A, Gonneaud J, Wirth M, et al
    Association between educational attainment and amyloid deposition across the spectrum from normal cognition to dementia: neuroimaging evidence for protection and compensation.
    Neurobiol Aging. 2017;59:72-79.
    PubMed     Text format     Abstract available


  70. MATHOTAARACHCHI S, Pascoal TA, Shin M, Benedet AL, et al
    Identifying incipient dementia individuals using machine learning and amyloid imaging.
    Neurobiol Aging. 2017;59:80-90.
    PubMed     Text format     Abstract available


  71. SWARDFAGER W, Yu D, Scola G, Cogo-Moreira H, et al
    Peripheral lipid oxidative stress markers are related to vascular risk factors and subcortical small vessel disease.
    Neurobiol Aging. 2017;59:91-97.
    PubMed     Text format     Abstract available


    October 2017
  72. BULK M, Abdelmoula WM, Nabuurs RJA, van der Graaf LM, et al
    Postmortem MRI and histology demonstrate differential iron accumulation and cortical myelin organization in early- and late-onset Alzheimer's disease.
    Neurobiol Aging. 2017;62:231-242.
    PubMed     Text format     Abstract available


  73. ROY U, Stute L, Hofling C, Hartlage-Rubsamen M, et al
    Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2017;62:168-179.
    PubMed     Text format     Abstract available


  74. VERHEIJEN J, van der Zee J, Gijselinck I, Van den Bossche T, et al
    Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort.
    Neurobiol Aging. 2017 Oct 25. pii: S0197-4580(17)30351.
    PubMed     Text format     Abstract available


  75. WANG JC, Alinaghi S, Tafakhori A, Sikora E, et al
    Genetic screening in two Iranian families with early-onset Alzheimer's disease identified a novel PSEN1 mutation.
    Neurobiol Aging. 2017 Oct 23. pii: S0197-4580(17)30350.
    PubMed     Text format     Abstract available


  76. GUTIERREZ-JIMENEZ E, Angleys H, Rasmussen PM, West MJ, et al
    Disturbances in the control of capillary flow in an aged APPswe/PS1DeltaE9 model of Alzheimer's disease.
    Neurobiol Aging. 2017;62:82-94.
    PubMed     Text format     Abstract available


  77. TSARTSALIS S, Xekardaki A, Hof PR, Kovari E, et al
    Early Alzheimer-type lesions in cognitively normal subjects.
    Neurobiol Aging. 2017;62:34-44.
    PubMed     Text format     Abstract available


  78. ROOSTAEI T, Felsky D, Nazeri A, De Jager PL, et al
    Genetic influence of plasma homocysteine on Alzheimer's disease.
    Neurobiol Aging. 2017 Oct 13. pii: S0197-4580(17)30337.
    PubMed     Text format     Abstract available


  79. CHAUDHURY S, Patel T, Barber IS, Guetta-Baranes T, et al
    Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease.
    Neurobiol Aging. 2017 Oct 10. pii: S0197-4580(17)30340.
    PubMed     Text format     Abstract available


  80. MECCA AP, Barcelos NM, Wang S, Bruck A, et al
    Cortical beta-amyloid burden, gray matter, and memory in adults at varying APOE epsilon4 risk for Alzheimer's disease.
    Neurobiol Aging. 2017;61:207-214.
    PubMed     Text format     Abstract available


  81. BRAWEK B, Chesters R, Klement D, Muller J, et al
    A bell-shaped dependence between amyloidosis and GABA accumulation in astrocytes in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2017;61:187-197.
    PubMed     Text format     Abstract available


  82. PENTKOWSKI NS, Berkowitz LE, Thompson SM, Drake EN, et al
    Anxiety-like behavior as an early endophenotype in the TgF344-AD rat model of Alzheimer's disease.
    Neurobiol Aging. 2017;61:169-176.
    PubMed     Text format     Abstract available


  83. VELAZQUEZ R, Tran A, Ishimwe E, Denner L, et al
    Corrigendum to "Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease" [Neurobiol. Aging 58 (2017) 1-13].
    Neurobiol Aging. 2017;58:241.
    PubMed     Text format    


  84. MORETTI DV, Pievani M, Pini L, Guerra UP, et al
    Cerebral PET glucose hypometabolism in subjects with mild cognitive impairment and higher EEG high-alpha/low-alpha frequency power ratio.
    Neurobiol Aging. 2017;58:213-224.
    PubMed     Text format     Abstract available


  85. TOUSSAY X, Morel JL, Biendon N, Rotureau L, et al
    Presenilin 1 mutation decreases both calcium and contractile responses in cerebral arteries.
    Neurobiol Aging. 2017;58:201-212.
    PubMed     Text format     Abstract available


  86. TANNINEN SE, Nouriziabari B, Morrissey MD, Bakir R, et al
    Entorhinal tau pathology disrupts hippocampal-prefrontal oscillatory coupling during associative learning.
    Neurobiol Aging. 2017;58:151-162.
    PubMed     Text format     Abstract available


  87. HARTLEY SL, Handen BL, Devenny D, Mihaila I, et al
    Cognitive decline and brain amyloid-beta accumulation across 3 years in adults with Down syndrome.
    Neurobiol Aging. 2017;58:68-76.
    PubMed     Text format     Abstract available


    September 2017
  88. GERAKIS Y, Hetz C
    A decay of the adaptive capacity of the unfolded protein response exacerbates Alzheimer's disease.
    Neurobiol Aging. 2017 Sep 22. pii: S0197-4580(17)30305.
    PubMed     Text format     Abstract available


  89. TIJMS BM, Ten Kate M, Gouw AA, Borta A, et al
    Gray matter networks and clinical progression in subjects with predementia Alzheimer's disease.
    Neurobiol Aging. 2017;61:75-81.
    PubMed     Text format     Abstract available


  90. THEOFILAS P, Ehrenberg AJ, Nguy A, Thackrey JM, et al
    Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.
    Neurobiol Aging. 2017;61:1-12.
    PubMed     Text format     Abstract available


  91. SAJAN MP, Hansen BC, Higgs MG, Kahn CR, et al
    Atypical PKC, PKClambda/iota, activates beta-secretase and increases Abeta1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormaliti
    Neurobiol Aging. 2017 Sep 15. pii: S0197-4580(17)30294.
    PubMed     Text format     Abstract available


  92. SOLDAN A, Pettigrew C, Cai Q, Wang J, et al
    Cognitive reserve and long-term change in cognition in aging and preclinical Alzheimer's disease.
    Neurobiol Aging. 2017;60:164-172.
    PubMed     Text format     Abstract available


  93. FERNANDEZ-DE RETANA S, Montanola A, Marazuela P, De La Cuesta M, et al
    Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease.
    Neurobiol Aging. 2017;60:116-128.
    PubMed     Text format     Abstract available


  94. OSGOOD D, Miller MC, Messier AA, Gonzalez L, et al
    Aging alters mRNA expression of amyloid transporter genes at the blood-brain barrier.
    Neurobiol Aging. 2017;57:178-185.
    PubMed     Text format     Abstract available


  95. GOUW AA, Alsema AM, Tijms BM, Borta A, et al
    EEG spectral analysis as a putative early prognostic biomarker in nondemented, amyloid positive subjects.
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    PubMed     Text format     Abstract available


  287. HUA X, Ching CR, Mezher A, Gutman BA, et al
    MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials.
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  288. CARRASQUILLO MM, Barber I, Lincoln SJ, Murray ME, et al
    Evaluating pathogenic dementia variants in posterior cortical atrophy.
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  289. FARFEL JM, Yu L, De Jager PL, Schneider JA, et al
    Association of APOE with tau-tangle pathology with and without beta-amyloid.
    Neurobiol Aging. 2016;37:19-25.
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    December 2015
  290. BARBER IS, Garcia-Cardenas JM, Sakdapanichkul C, Deacon C, et al
    Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease.
    Neurobiol Aging. 2015 Dec 29. pii: S0197-4580(15)00615.
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  291. WANG YQ, Tang BS, Yang Y, Cui YT, et al
    Relationship between Alzheimer's disease GWAS-linked top hits and risk of Parkinson's disease with or without cognitive decline: a Chinese population-based study.
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  292. MASTROENI D, Delvaux E, Nolz J, Tan Y, et al
    Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease.
    Neurobiol Aging. 2015;36:3121-9.
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    November 2015
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    Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases.
    Neurobiol Aging. 2015 Nov 2. pii: S0197-4580(15)00540.
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    October 2015
  294. NIBLOCK M, Hortobagyi T, Troakes C, Al-Sarraj S, et al
    Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease.
    Neurobiol Aging. 2015 Oct 9. pii: S0197-4580(15)00479.
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  295. FERNANDEZ-MARTOS CM, King AE, Atkinson RA, Woodhouse A, et al
    Neurofilament light gene deletion exacerbates amyloid, dystrophic neurite, and synaptic pathology in the APP/PS1 transgenic model of Alzheimer's disease.
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    September 2015
  296. BLAUWENDRAAT C, Wilke C, Jansen IE, Schulte C, et al
    Pilot whole-exome sequencing of a German early-onset Alzheimer's disease cohort reveals a substantial frequency of PSEN2 variants.
    Neurobiol Aging. 2015 Sep 30. pii: S0197-4580(15)00473.
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  297. DEMING Y, Xia J, Cai Y, Lord J, et al
    A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin.
    Neurobiol Aging. 2015 Sep 25. pii: S0197-4580(15)00466.
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  298. MAKEDONOV I, Chen JJ, Masellis M, MacIntosh BJ, et al
    Physiological fluctuations in white matter are increased in Alzheimer's disease and correlate with neuroimaging and cognitive biomarkers.
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  299. SON SM, Nam DW, Cha MY, Kim KH, et al
    Thrombospondin-1 prevents amyloid beta-mediated synaptic pathology in Alzheimer's disease.
    Neurobiol Aging. 2015 Sep 14. pii: S0197-4580(15)00451.
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  300. TRISTAN-CLAVIJO E, Camacho-Garcia RJ, Robles-Lanuza E, Ruiz A, et al
    A truncating mutation in Alzheimer's disease inactivates neuroligin-1 synaptic function.
    Neurobiol Aging. 2015 Sep 10. pii: S0197-4580(15)00450.
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  301. XIA M, Chen S, Shi Y, Huang Y, et al
    Probable novel PSEN2 Pro123Leu mutation in a Chinese Han family of Alzheimer's disease.
    Neurobiol Aging. 2015 Sep 8. pii: S0197-4580(15)00449.
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  302. AHMADIAN SS, Rezvanian A, Peterson M, Weintraub S, et al
    Loss of calbindin-D is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease.
    Neurobiol Aging. 2015 Sep 6. pii: S0197-4580(15)00446.
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  303. RYAN NS, Biessels GJ, Kim L, Nicholas JM, et al
    Genetic determinants of white matter hyperintensities and amyloid angiopathy in familial Alzheimer's disease.
    Neurobiol Aging. 2015 Sep 4. pii: S0197-4580(15)00443.
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    August 2015
  304. BARRAL S, Vardarajan BN, Faber KM, Bird TD, et al
    Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families.
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  305. ROSENTHAL SL, Bamne MN, Wang X, Berman S, et al
    More evidence for association of a rare TREM2 mutation (R47H) with Alzheimer's disease risk.
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  306. VARNUM MM, Kiyota T, Ingraham KL, Ikezu S, et al
    The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2015 Aug 1. pii: S0197-4580(15)00393.
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  307. ROSA E, Fahnestock M
    CREB expression mediates amyloid beta-induced basal BDNF downregulation.
    Neurobiol Aging. 2015;36:2406-13.
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  308. RESNICK SM, Bilgel M, Moghekar A, An Y, et al
    Changes in Abeta biomarkers and associations with APOE genotype in 2 longitudinal cohorts.
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    July 2015
  309. VITICCHI G, Falsetti L, Buratti L, Boria C, et al
    Framingham risk score can predict cognitive decline progression in Alzheimer's disease.
    Neurobiol Aging. 2015 Jul 26. pii: S0197-4580(15)00383.
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  310. LEHMANN M, Madison C, Ghosh PM, Miller ZA, et al
    Loss of functional connectivity is greater outside the default mode network in nonfamilial early-onset Alzheimer's disease variants.
    Neurobiol Aging. 2015 Jul 16. pii: S0197-4580(15)00374.
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  311. ZHOU X, Xu J
    Identification of Alzheimer's disease-associated long noncoding RNAs.
    Neurobiol Aging. 2015 Jul 16. pii: S0197-4580(15)00372.
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  312. HAMELIN L, Bertoux M, Bottlaender M, Corne H, et al
    Sulcal morphology as a new imaging marker for the diagnosis of early onset Alzheimer's disease.
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  313. LIM YY, Maruff P, Schindler R, Ott BR, et al
    Disruption of cholinergic neurotransmission exacerbates Abeta-related cognitive impairment in preclinical Alzheimer's disease.
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  314. GISPERT JD, Rami L, Sanchez-Benavides G, Falcon C, et al
    Nonlinear cerebral atrophy patterns across the Alzheimer's disease continuum: impact of APOE4 genotype.
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  315. BRENOWITZ WD, Nelson PT, Besser LM, Heller KB, et al
    Cerebral amyloid angiopathy and its co-occurrence with Alzheimer's disease and other cerebrovascular neuropathologic changes.
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  316. JYOTI A, Plano A, Riedel G, Platt B, et al
    Progressive age-related changes in sleep and EEG profiles in the PLB1 mouse model of Alzheimer's disease.
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  317. TORRALVA T, Sposato LA, Riccio PM, Gleichgerrcht E, et al
    Role of brain infarcts in behavioral variant frontotemporal dementia: Clinicopathological characterization in the National Alzheimer's Coordinating Center database.
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    June 2015
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    Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.
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  319. MUCHNIK C, Olivar N, Dalmasso MC, Azurmendi PJ, et al
    Identification of PSEN2 mutation p.N141I in Argentine pedigrees with early-onset familial Alzheimer's disease.
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  320. BAO X, Liu G, Jiang Y, Jiang Q, et al
    Cell adhesion molecule pathway genes are regulated by cis-regulatory SNPs and show significantly altered expression in Alzheimer's disease brains.
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  321. ACHOURI-RASSAS A, Ben Ali N, Fray S, Hadj Fredj S, et al
    Novel presenilin 1 mutation (p.I83T) in Tunisian family with early-onset Alzheimer's disease.
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  322. HOHMAN TJ, Samuels LR, Liu D, Gifford KA, et al
    Stroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes.
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  323. CHIU C, Miller MC, Monahan R, Osgood DP, et al
    P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations.
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  324. ZEINEH MM, Chen Y, Kitzler HH, Hammond R, et al
    Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease.
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  325. PERAZA LR, Taylor JP, Kaiser M
    Divergent brain functional network alterations in dementia with Lewy bodies and Alzheimer's disease.
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  326. TEIPEL SJ, Grothe MJ, Wittfeld K, Hoffmann W, et al
    Association of a neurokinin 3 receptor polymorphism with the anterior basal forebrain.
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    Acute amnestic encephalopathy in amyloid-beta oligomer-injected mice is due to their widespread diffusion in vivo.
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  329. DOTY RL, Tourbier I, Ng V, Neff J, et al
    Influences of hormone replacement therapy on olfactory and cognitive function in postmenopausal women.
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    May 2015
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    Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease.
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  331. LINDEMER ER, Salat DH, Smith EE, Nguyen K, et al
    White matter signal abnormality quality differentiates mild cognitive impairment that converts to Alzheimer's disease from nonconverters.
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    Effects of noninvasive brain stimulation on cognitive function in healthy aging and Alzheimer's disease: a systematic review and meta-analysis.
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  333. KUBOYAMA T, Lee YA, Nishiko H, Tohda C, et al
    Inhibition of clathrin-mediated endocytosis prevents amyloid beta-induced axonal damage.
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    April 2015
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    JNK-interacting protein 1 mediates Alzheimer's-like pathological features in AICD-transgenic mice.
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  335. OSSENKOPPELE R, Mattsson N, Teunissen CE, Barkhof F, et al
    Cerebrospinal fluid biomarkers and cerebral atrophy in distinct clinical variants of probable Alzheimer's disease.
    Neurobiol Aging. 2015 Apr 25. pii: S0197-4580(15)00231.
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  336. ZUMKEHR J, Rodriguez-Ortiz CJ, Cheng D, Kieu Z, et al
    Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2015 Apr 16. pii: S0197-4580(15)00206.
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  337. SERRIERE S, Tauber C, Vercouillie J, Mothes C, et al
    Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study.
    Neurobiol Aging. 2015;36:1639-52.
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    March 2015
  338. LAMBRACHT-WASHINGTON D, Rosenberg RN
    A noninflammatory immune response in aged DNA Abeta42-immunized mice supports its safety for possible use as immunotherapy in AD patients.
    Neurobiol Aging. 2015;36:1274-81.
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  339. MABLY AJ, Kanmert D, Mc Donald JM, Liu W, et al
    Tau immunization: a cautionary tale?
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  340. TIAN H, Davidowitz E, Lopez P, He P, et al
    Isolation and characterization of antibody fragments selective for toxic oligomeric tau.
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  341. HOU P, Liu G, Zhao Y, Shi Z, et al
    Role of copper and the copper-related protein CUTA in mediating APP processing and Abeta generation.
    Neurobiol Aging. 2015;36:1310-5.
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  342. SCHAFER MJ, Alldred MJ, Lee SH, Calhoun ME, et al
    Reduction of beta-amyloid and gamma-secretase by calorie restriction in female Tg2576 mice.
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  343. CRISCUOLO C, Fabiani C, Bonadonna C, Origlia N, et al
    BDNF prevents amyloid-dependent impairment of LTP in the entorhinal cortex by attenuating p38 MAPK phosphorylation.
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  344. TAKACH O, Gill TB, Silverman MA
    Modulation of insulin signaling rescues BDNF transport defects independent of tau in amyloid-beta oligomer-treated hippocampal neurons.
    Neurobiol Aging. 2015;36:1378-82.
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  345. LUNNON K, Smith RG, Cooper I, Greenbaum L, et al
    Blood methylomic signatures of presymptomatic dementia in elderly subjects with type 2 diabetes mellitus.
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  346. ORR ME, Garbarino VR, Salinas A, Buffenstein R, et al
    Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
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  347. GIBBONS L, Rollinson S, Thompson JC, Robinson A, et al
    Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration.
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    February 2015
  348. SCALA F, Fusco S, Ripoli C, Piacentini R, et al
    Intraneuronal Abeta accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3.
    Neurobiol Aging. 2015;36:886-900.
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  349. NOEL A, Poitras I, Julien J, Petry FR, et al
    ERK (MAPK) does not phosphorylate tau under physiological conditions in vivo or in vitro.
    Neurobiol Aging. 2015;36:901-2.
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  350. SOLE M, Minano-Molina AJ, Unzeta M
    Cross-talk between Abeta and endothelial SSAO/VAP-1 accelerates vascular damage and Abeta aggregation related to CAA-AD.
    Neurobiol Aging. 2015;36:762-75.
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  351. KATSOURI L, Ashraf A, Birch AM, Lee KK, et al
    Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice.
    Neurobiol Aging. 2015;36:821-31.
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  352. FENG J, Meng C, Xing D
    Abeta induces PUMA activation: a new mechanism for Abeta-mediated neuronal apoptosis.
    Neurobiol Aging. 2015;36:789-800.
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  353. OU-YANG MH, Xu F, Liao MC, Davis J, et al
    N-terminal region of myelin basic protein reduces fibrillar amyloid-beta deposition in Tg-5xFAD mice.
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  354. LAURETTI E, Di Meco A, Chu J, Pratico D, et al
    Modulation of AD neuropathology and memory impairments by the isoprostane F2alpha is mediated by the thromboxane receptor.
    Neurobiol Aging. 2015;36:812-20.
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  355. LAZZARI C, Kipanyula MJ, Agostini M, Pozzan T, et al
    Abeta42 oligomers selectively disrupt neuronal calcium release.
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  356. MUNOZ G, Urrutia JC, Burgos CF, Silva V, et al
    Low concentrations of ethanol protect against synaptotoxicity induced by Abeta in hippocampal neurons.
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    Striatum and entorhinal cortex atrophy in AD mouse models: MRI comprehensive analysis.
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  358. PACHECO J, Goh JO, Kraut MA, Ferrucci L, et al
    Greater cortical thinning in normal older adults predicts later cognitive impairment.
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    January 2015
  359. NIR TM, Jahanshad N, Toga AW, Bernstein MA, et al
    Connectivity network measures predict volumetric atrophy in mild cognitive impairment.
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  360. RAAMANA PR, Weiner MW, Wang L, Beg MF, et al
    Thickness network features for prognostic applications in dementia.
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  361. CHING CR, Hua X, Hibar DP, Ward CP, et al
    Does MRI scan acceleration affect power to track brain change?
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    Anterior and posterior MTL networks in aging and MCI.
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    Cortical surface biomarkers for predicting cognitive outcomes using group l2,1 norm.
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    Mapping ventricular expansion onto cortical gray matter in older adults.
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  365. KHAN AR, Wang L, Beg MF
    Unified voxel- and tensor-based morphometry (UVTBM) using registration confidence.
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  366. PRADOS F, Cardoso MJ, Leung KK, Cash DM, et al
    Measuring brain atrophy with a generalized formulation of the boundary shift integral.
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  367. HIBAR DP, Stein JL, Jahanshad N, Kohannim O, et al
    Genome-wide interaction analysis reveals replicated epistatic effects on brain structure.
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    Seemingly unrelated regression empowers detection of network failure in dementia.
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  369. BOURGEAT P, Villemagne VL, Dore V, Brown B, et al
    Comparison of MR-less PiB SUVR quantification methods.
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