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Articles published in Neurobiol Aging

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    August 2021
  1. WHITWELL JL, Tosakulwong N, Weigand SD, Graff-Radford J, et al
    Relationship of APOE, age at onset, amyloid and clinical phenotype in Alzheimer disease.
    Neurobiol Aging. 2021;108:90-98.
    PubMed     Abstract available

  2. ZHANG Z, Wang M, Liu X
    C-reactive protein and risk of Alzheimer's disease.
    Neurobiol Aging. 2021 Aug 21. pii: S0197-4580(21)00264.
    PubMed     Abstract available

  3. PALIWAL D, McInerney TW, Pa J, Swerdlow RH, et al
    Mitochondrial pathway polygenic risk scores are associated with Alzheimer's Disease.
    Neurobiol Aging. 2021 Aug 18. pii: S0197-4580(21)00259.
    PubMed     Abstract available

  4. SHEPHERD A, Lim JKH, Wong VHY, Zeleznikow-Johnston AM, et al
    Progressive impairments in executive function in the APP/PS1 model of Alzheimer's disease as measured by translatable touchscreen testing.
    Neurobiol Aging. 2021;108:58-71.
    PubMed     Abstract available

  5. WILLEMSE EAJ, Sieben A, Somers C, Vermeiren Y, et al
    Neurogranin as biomarker in CSF is non-specific to Alzheimer's disease dementia.
    Neurobiol Aging. 2021;108:99-109.
    PubMed     Abstract available

    Retraction notice to "Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease" [Neurobiology of Aging Volume 68, August 2018, Page 59-67].
    Neurobiol Aging. 2021;104:139.

    July 2021
  7. FLEMING V, Piro-Gambetti B, Patrick A, Zammit M, et al
    Physical activity and cognitive and imaging biomarkers of Alzheimer's disease in down syndrome.
    Neurobiol Aging. 2021;107:118-127.
    PubMed     Abstract available

  8. TATARYN NM, Singh V, Dyke JP, Berk-Rauch HE, et al
    Vascular endothelial growth factor associated dissimilar cerebrovascular phenotypes in two different mouse models of Alzheimer's Disease.
    Neurobiol Aging. 2021;107:96-108.
    PubMed     Abstract available

    Emerging roles of oxidative stress in brain aging and Alzheimer's disease.
    Neurobiol Aging. 2021;107:86-95.
    PubMed     Abstract available

  10. LIM B, Grontvedt GR, Bathala P, Kale SS, et al
    CSF neurofilament light may predict progression from amnestic mild cognitive impairment to Alzheimer's disease dementia.
    Neurobiol Aging. 2021;107:78-85.
    PubMed     Abstract available

  11. MIN S, Li Z, Shieh A, Giase G, et al
    Absence of coding somatic single nucleotide variants within well-known candidate genes in late-onset sporadic Alzheimer's Disease based on the analysis of multi-omics data.
    Neurobiol Aging. 2021 Jul 21. pii: S0197-4580(21)00236.
    PubMed     Abstract available

  12. LEMERCIER P, Vergallo A, Lista S, Zetterberg H, et al
    Association of plasma Abeta40/Abeta42 ratio and brain Abeta accumulation: testing a whole-brain PLS-VIP approach in individuals at risk of Alzheimer's disease.
    Neurobiol Aging. 2021;107:57-69.
    PubMed     Abstract available

  13. NAUDE PJW, Ramakers IHGB, van der Flier WM, Jiskoot LC, et al
    Serum and cerebrospinal fluid Neutrophil gelatinase-associated lipocalin (NGAL) levels as biomarkers for the conversion from mild cognitive impairment to Alzheimer's disease dementia.
    Neurobiol Aging. 2021;107:1-10.
    PubMed     Abstract available

  14. VAN DER LINDEN RJ, Reus LM, De Witte W, Tijms BM, et al
    Genetic overlap between Alzheimer's disease and blood lipid levels.
    Neurobiol Aging. 2021 Jul 3. pii: S0197-4580(21)00213.
    PubMed     Abstract available

    June 2021
  15. RUSSO ML, Molina-Campos E, Ybarra N, Rogalsky AE, et al
    Variability in sub-threshold signaling linked to Alzheimer's disease emerges with age and amyloid plaque deposition in mouse ventral CA1 pyramidal neurons.
    Neurobiol Aging. 2021;106:207-222.
    PubMed     Abstract available

  16. ZADEY S, Buss SS, McDonald K, Press DZ, et al
    Higher motor cortical excitability linked to greater cognitive dysfunction in Alzheimer's disease: results from two independent cohorts.
    Neurobiol Aging. 2021;108:24-33.
    PubMed     Abstract available

  17. PFEIL J, Hoenig MC, Doering E, van Eimeren T, et al
    Unique regional patterns of amyloid burden predict progression to prodromal and clinical stages of Alzheimer's disease.
    Neurobiol Aging. 2021;106:119-129.
    PubMed     Abstract available

  18. JUNG JH, Jeon S, Baik K, Lee YH, et al
    Apolipoprotein E4, amyloid, and cognition in Alzheimer's and Lewy body disease.
    Neurobiol Aging. 2021;106:45-54.
    PubMed     Abstract available

  19. SANGHA O, Ma D, Popuri K, Stocks J, et al
    Structural volume and cortical thickness differences between males and females in cognitively normal, cognitively impaired and Alzheimer's dementia population.
    Neurobiol Aging. 2021;106:1-11.
    PubMed     Abstract available

  20. BANKS SJ, Andrews MJ, Digma L, Madsen J, et al
    Sex differences in Alzheimer's disease: do differences in tau explain the verbal memory gap?
    Neurobiol Aging. 2021;107:70-77.
    PubMed     Abstract available

    May 2021
  21. XIAO X, Yuan Z, Guo L, Liao X, et al
    The role of frontotemporal dementia associated genes in patients with Alzheimer's disease.
    Neurobiol Aging. 2021 May 30. pii: S0197-4580(21)00179.
    PubMed     Abstract available

  22. TUBI MA, Kothapalli D, Hapenney M, Feingold FW, et al
    Regional relationships between CSF VEGF levels and Alzheimer's disease brain biomarkers and cognition.
    Neurobiol Aging. 2021;105:241-251.
    PubMed     Abstract available

  23. GAUBERT S, Houot M, Raimondo F, Ansart M, et al
    A machine learning approach to screen for preclinical Alzheimer's disease.
    Neurobiol Aging. 2021;105:205-216.
    PubMed     Abstract available

  24. BOSSAERTS L, Hens E, Hanseeuw B, Vandenberghe R, et al
    Premature termination codon mutations in ABCA7 contribute to Alzheimer's disease risk in Belgian patients.
    Neurobiol Aging. 2021 May 2. pii: S0197-4580(21)00146.
    PubMed     Abstract available

    April 2021
  25. TSAKIRI EN, Gumeni S, Manola MS, Trougakos IP, et al
    Amyloid toxicity in a Drosophila Alzheimer's model is ameliorated by autophagy activation.
    Neurobiol Aging. 2021;105:137-147.
    PubMed     Abstract available

  26. EDWARDS L, La Joie R, Iaccarino L, Strom A, et al
    Multimodal neuroimaging of sex differences in cognitively impaired patients on the Alzheimer's continuum: greater tau-PET retention in females.
    Neurobiol Aging. 2021;105:86-98.
    PubMed     Abstract available

  27. RABIPOUR S, Rajagopal S, Pasvanis S, Rajah MN, et al
    Generalization of memory-related brain function in asymptomatic older women with a family history of late onset Alzheimer's Disease: Results from the PREVENT-AD Cohort.
    Neurobiol Aging. 2021;104:42-56.
    PubMed     Abstract available

    March 2021
  28. HOOGMARTENS J, Hens E, Engelborghs S, De Deyn PP, et al
    Investigation of the role of matrix metalloproteinases in the genetic etiology of Alzheimer's disease.
    Neurobiol Aging. 2021 Mar 28. pii: S0197-4580(21)00102.
    PubMed     Abstract available

  29. CASH MK, Rockwood K, Fisk JD, Darvesh S, et al
    Clinicopathological correlations and cholinesterase expression in early-onset familial Alzheimer's disease with the presenilin 1 mutation, Leu235Pro.
    Neurobiol Aging. 2021;103:31-41.
    PubMed     Abstract available

  30. HU K, Li P, Gao L
    Sleep, rest-activity rhythms and aging: a complex web in Alzheimer's disease?
    Neurobiol Aging. 2021 Mar 2. pii: S0197-4580(21)00072.

    February 2021
  31. NUEBLING GS, Prix C, Brendel M, Beyer L, et al
    Low-degree trisomy 21 mosaicism promotes early-onset Alzheimer disease.
    Neurobiol Aging. 2021 Feb 28. pii: S0197-4580(21)00076.
    PubMed     Abstract available

  32. CACCIOTTOLO M, Morgan TE, Finch CE
    Age, sex, and cerebral microbleeds in EFAD Alzheimer disease mice.
    Neurobiol Aging. 2021;103:42-51.
    PubMed     Abstract available

  33. RAJABLI F, Feliciano-Astacio BE, Cukier HN, Wang L, et al
    Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.
    Neurobiol Aging. 2021 Feb 28. pii: S0197-4580(21)00074.
    PubMed     Abstract available

  34. BETTCHER BM, Olson KE, Carlson NE, McConnell BV, et al
    Astrogliosis and episodic memory in late life: higher GFAP is related to worse memory and white matter microstructure in healthy aging and Alzheimer's disease.
    Neurobiol Aging. 2021;103:68-77.
    PubMed     Abstract available

  35. KARA F, Belloy ME, Voncken R, Sarwari Z, et al
    Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer's disease.
    Neurobiol Aging. 2021;102:139-150.
    PubMed     Abstract available

  36. RUBINSKI A, Tosun D, Franzmeier N, Neitzel J, et al
    Lower cerebral perfusion is associated with tau-PET in the entorhinal cortex across the Alzheimer's continuum.
    Neurobiol Aging. 2021;102:111-118.
    PubMed     Abstract available

  37. VAN HOOREN RWE, Verhey FRJ, Ramakers IHGB, Jansen WJ, et al
    Elevated norepinephrine metabolism is linked to cortical thickness in the context of Alzheimer's disease pathology.
    Neurobiol Aging. 2021;102:17-22.
    PubMed     Abstract available

  38. GIOVAGNONI C, Ali M, Eijssen LMT, Maes R, et al
    Altered sphingolipid function in Alzheimer's disease; a gene regulatory network approach.
    Neurobiol Aging. 2021;102:178-187.
    PubMed     Abstract available

  39. O'CONNOR A, Abel E, Fraser MR, Ryan NS, et al
    A novel presenilin 1 duplication mutation (Ile168dup) causing Alzheimer's disease associated with myoclonus, seizures and pyramidal features.
    Neurobiol Aging. 2021 Feb 5. pii: S0197-4580(21)00046.
    PubMed     Abstract available

  40. ALLISON SL, Jonaitis EM, Koscik RL, Hermann BP, et al
    Neurodegeneration, Alzheimer's disease biomarkers, and longitudinal verbal learning and memory performance in late middle age.
    Neurobiol Aging. 2021;102:151-160.
    PubMed     Abstract available

  41. CHUNG SJ, Lee S, Yoo HS, Baik K, et al
    Different patterns of beta-amyloid deposition in patients with Alzheimer's disease according to the presence of mild parkinsonism.
    Neurobiol Aging. 2021;101:199-206.
    PubMed     Abstract available

  42. KIM BH, Nho K, Lee JM
    Genome-wide association study identifies susceptibility loci of brain atrophy to NFIA and ST18 in Alzheimer's disease.
    Neurobiol Aging. 2021 Feb 3. pii: S0197-4580(21)00028.
    PubMed     Abstract available

  43. WISSE LEM, Ungrady MB, Ittyerah R, Lim SA, et al
    Cross-sectional and longitudinal medial temporal lobe subregional atrophy patterns in semantic variant primary progressive aphasia.
    Neurobiol Aging. 2021;98:231-241.
    PubMed     Abstract available

  44. GUO C, Zhang Y, Nie Q, Cao D, et al
    SQSTM1/ p62 oligomerization contributes to Abeta-induced inhibition of Nrf2 signaling.
    Neurobiol Aging. 2021;98:10-20.
    PubMed     Abstract available

  45. MUSCAT SM, Deems NP, D'Angelo H, Kitt MM, et al
    Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats.
    Neurobiol Aging. 2021;98:214-224.
    PubMed     Abstract available

  46. YEUNG LK, Hale C, Rizvi B, Igwe K, et al
    Anterolateral entorhinal cortex volume is associated with memory retention in clinically unimpaired older adults.
    Neurobiol Aging. 2021;98:134-145.
    PubMed     Abstract available

  47. LOW A, Su L, Stefaniak JD, Mak E, et al
    Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study.
    Neurobiol Aging. 2021;98:124-133.
    PubMed     Abstract available

  48. MEEKER KL, Ances BM, Gordon BA, Rudolph CW, et al
    Cerebrospinal fluid Abeta42 moderates the relationship between brain functional network dynamics and cognitive intraindividual variability.
    Neurobiol Aging. 2021;98:116-123.
    PubMed     Abstract available

    January 2021
  49. PARK JE, Lee YJ, Byun MS, Yi D, et al
    Differential associations of age and Alzheimer's disease with sleep and rest-activity rhythms across the adult lifespan.
    Neurobiol Aging. 2021;101:141-149.
    PubMed     Abstract available

  50. MONDRAGON JD, Maurits NM, De Deyn PP
    Functional connectivity differences in Alzheimer's disease and amnestic mild cognitive impairment associated with AT(N) classification and anosognosia.
    Neurobiol Aging. 2021;101:22-39.
    PubMed     Abstract available

  51. CHENG Z, Shang Y, Xu X, Dong Z, et al
    Presenilin 1 mutation likely contributes to U1 small nuclear RNA dysregulation and Alzheimer's disease-like symptoms.
    Neurobiol Aging. 2021;100:1-10.
    PubMed     Abstract available

  52. DECKER Y, Nemeth E, Schomburg R, Chemla A, et al
    Decreased pH in the aging brain and Alzheimer's disease.
    Neurobiol Aging. 2021;101:40-49.
    PubMed     Abstract available

  53. PALTA P, Rippon B, Tahmi M, Sherwood G, et al
    Metabolic syndrome and its components in relation to in vivo brain amyloid and neurodegeneration in late middle age.
    Neurobiol Aging. 2021;97:89-96.
    PubMed     Abstract available

    December 2020
  54. MIYAGAWA T, Przybelski SA, Maltais D, Min HK, et al
    The value of multimodal imaging with (123)I-FP-CIT SPECT in differential diagnosis of dementia with Lewy bodies and Alzheimer's disease dementia.
    Neurobiol Aging. 2020;99:11-18.
    PubMed     Abstract available

  55. BAE J, Stocks J, Heywood A, Jung Y, et al
    Transfer learning for predicting conversion from mild cognitive impairment to dementia of Alzheimer's type based on a three-dimensional convolutional neural network.
    Neurobiol Aging. 2020;99:53-64.
    PubMed     Abstract available

  56. MARCA-YSABEL MV, Rajabli F, Cornejo-Olivas M, Whitehead PG, et al
    Dissecting the role of Amerindian genetic ancestry and the ApoE epsilon4 allele on Alzheimer disease in an admixed Peruvian population.
    Neurobiol Aging. 2020 Dec 10. pii: S0197-4580(20)30312.
    PubMed     Abstract available

  57. WENG FL, He L
    Disrupted ubiquitin proteasome system underlying tau accumulation in Alzheimer's disease.
    Neurobiol Aging. 2020;99:79-85.
    PubMed     Abstract available

    November 2020
  58. YANG W, Zhou X, Ryazanov AG, Ma T, et al
    Suppression of the kinase for elongation factor 2 alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2020;98:225-230.
    PubMed     Abstract available

  59. LAWINGCO T, Chaudhury S, Brookes KJ, Guetta-Baranes T, et al
    Genetic variants in glutamate-, Abeta-, and tau-related pathways determine polygenic risk for Alzheimer's disease.
    Neurobiol Aging. 2020 Nov 12. pii: S0197-4580(20)30391.
    PubMed     Abstract available

  60. ZHUANG Z, Gao M, Yang R, Liu Z, et al
    Causal relationships between gut metabolites and Alzheimer's disease: a bidirectional Mendelian randomization study.
    Neurobiol Aging. 2020 Nov 12. pii: S0197-4580(20)30334.
    PubMed     Abstract available

  61. FOO H, Thalamuthu A, Jiang J, Koch F, et al
    Associations between Alzheimer's disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participants.
    Neurobiol Aging. 2020;98:108-115.
    PubMed     Abstract available

  62. MANZALI SB, Ravona-Springer R, Alkelai A, Yu E, et al
    Association of the CD2AP locus with cognitive functioning among middle-aged individuals with a family history of Alzheimer's disease.
    Neurobiol Aging. 2020;101:50-56.
    PubMed     Abstract available

  63. MURRAY AN, Chandler HL, Lancaster TM
    Multimodal hippocampal and amygdala subfield volumetry in polygenic risk for Alzheimer's disease.
    Neurobiol Aging. 2020;98:33-41.
    PubMed     Abstract available

    October 2020
  64. SALAZAR AM, Leisgang AM, Ortiz AA, Murtishaw AS, et al
    Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
    Neurobiol Aging. 2020;97:129-143.
    PubMed     Abstract available

  65. GAUBA E, Sui S, Tian J, Driskill C, et al
    Modulation of OSCP mitigates mitochondrial and synaptic deficits in a mouse model of Alzheimer's pathology.
    Neurobiol Aging. 2020;98:63-77.
    PubMed     Abstract available

  66. HENDRIX RD, Ou Y, Davis JE, Odle AK, et al
    Alzheimer amyloid-beta- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood.
    Neurobiol Aging. 2020;97:73-88.
    PubMed     Abstract available

  67. KWOK MK, Schooling CM
    Herpes simplex virus and Alzheimer's disease: a Mendelian randomization study.
    Neurobiol Aging. 2020 Oct 9. pii: S0197-4580(20)30309.
    PubMed     Abstract available

  68. PAES D, Lardenoije R, Carollo RM, Roubroeks JAY, et al
    Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer's disease.
    Neurobiol Aging. 2020;97:56-64.
    PubMed     Abstract available

  69. LIU D, Wang Y, Jing H, Meng Q, et al
    Mendelian randomization integrating GWAS and mQTL data identified novel pleiotropic DNA methylation loci for neuropathology of Alzheimer's disease.
    Neurobiol Aging. 2020;97:18-27.
    PubMed     Abstract available

    September 2020
  70. FULTON-HOWARD B, Goate AM, Adelson RP, Koppel J, et al
    Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-epsilon4 carriers.
    Neurobiol Aging. 2020 Sep 30. pii: S0197-4580(20)30291.
    PubMed     Abstract available

  71. WALSH P, Sudre CH, Fiford CM, Ryan NS, et al
    The age-dependent associations of white matter hyperintensities and neurofilament light in early- and late-stage Alzheimer's disease.
    Neurobiol Aging. 2020;97:10-17.
    PubMed     Abstract available

  72. HOOGMARTENS J, Hens E, Engelborghs S, Vandenberghe R, et al
    Contribution of homozygous and compound heterozygous missense mutations in VWA2 to Alzheimer's disease.
    Neurobiol Aging. 2020 Sep 12. pii: S0197-4580(20)30286.
    PubMed     Abstract available

  73. GUO B, Huang Y, Gao Q, Zhou Q, et al
    Stabilization of microtubules improves cognitive functions and axonal transport of mitochondria in Alzheimer's disease model mice.
    Neurobiol Aging. 2020;96:223-232.
    PubMed     Abstract available

  74. MASSA F, Grisanti S, Brugnolo A, Doglione E, et al
    The role of anterior prefrontal cortex in prospective memory: an exploratory FDG-PET study in early Alzheimer's disease.
    Neurobiol Aging. 2020;96:117-127.
    PubMed     Abstract available

  75. CACERES A, Gonzalez JR
    Female-specific risk of Alzheimer's disease is associated with tau phosphorylation processes: A transcriptome-wide interaction analysis.
    Neurobiol Aging. 2020;96:104-108.
    PubMed     Abstract available

  76. FRANCIOTTI R, Pilotto A, Moretti DV, Falasca NW, et al
    Anterior EEG slowing in dementia with Lewy bodies: a multicenter European cohort study.
    Neurobiol Aging. 2020;93:55-60.
    PubMed     Abstract available

  77. CODY KA, Piro-Gambetti B, Zammit MD, Christian BT, et al
    Association of sleep with cognition and beta amyloid accumulation in adults with Down syndrome.
    Neurobiol Aging. 2020;93:44-51.
    PubMed     Abstract available

  78. RAMOS-CAMPOY O, Antonell A, Falgas N, Balasa M, et al
    Screening of dementia genes by whole-exome sequencing in Spanish patients with early-onset dementia: likely pathogenic, uncertain significance and risk variants.
    Neurobiol Aging. 2020;93:e1-e9.
    PubMed     Abstract available

  79. RABIN JS, Shirzadi Z, Swardfager W, MacIntosh BJ, et al
    Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults.
    Neurobiol Aging. 2020;93:124-130.
    PubMed     Abstract available

    August 2020
  80. MILLAR PR, Ances BM, Gordon BA, Benzinger TLS, et al
    Evaluating resting-state BOLD variability in relation to biomarkers of preclinical Alzheimer's disease.
    Neurobiol Aging. 2020;96:233-245.
    PubMed     Abstract available

    July 2020
  81. ANDERSSON E, Janelidze S, Lampinen B, Nilsson M, et al
    Blood and cerebrospinal fluid neurofilament light differentially detect neurodegeneration in early Alzheimer's disease.
    Neurobiol Aging. 2020;95:143-153.
    PubMed     Abstract available

  82. BERTOUX M, Cassagnaud P, Lebouvier T, Lebert F, et al
    Does amnesia specifically predict Alzheimer's pathology? A neuropathological study.
    Neurobiol Aging. 2020;95:123-130.
    PubMed     Abstract available

  83. RUSSO-SAVAGE L, Rao VKS, Eipper BA, Mains RE, et al
    Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer's disease model mouse line.
    Neurobiol Aging. 2020;95:69-80.
    PubMed     Abstract available

  84. RINGLAND C, Schweig JE, Paris D, Shackleton B, et al
    Apolipoprotein E isoforms differentially regulate matrix metallopeptidase 9 function in Alzheimer's disease.
    Neurobiol Aging. 2020;95:56-68.
    PubMed     Abstract available

  85. ROUBROEKS JAY, Smith AR, Smith RG, Pishva E, et al
    An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene.
    Neurobiol Aging. 2020;95:26-45.
    PubMed     Abstract available

  86. BROKAW DL, Piras IS, Mastroeni D, Weisenberger DJ, et al
    Cell death and survival pathways in Alzheimer's disease: an integrative hypothesis testing approach utilizing -omic data sets.
    Neurobiol Aging. 2020;95:15-25.
    PubMed     Abstract available

    The influence of Abeta-dependent and independent pathways on TDP-43 proteinopathy in Alzheimer's disease: a possible connection to LATE-NC.
    Neurobiol Aging. 2020;95:161-167.
    PubMed     Abstract available

  88. DOUNAVI ME, Mak E, Wells K, Ritchie K, et al
    Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia.
    Neurobiol Aging. 2020;91:36-44.
    PubMed     Abstract available

  89. ZHOU F, Yan XD, Wang C, He YX, et al
    Suvorexant ameliorates cognitive impairments and pathology in APP/PS1 transgenic mice.
    Neurobiol Aging. 2020;91:66-75.
    PubMed     Abstract available

    June 2020
  90. HALLAM B, Chan J, Gonzalez Costafreda S, Bhome R, et al
    What are the neural correlates of meta-cognition and anosognosia in Alzheimer's disease? A systematic review.
    Neurobiol Aging. 2020;94:250-264.
    PubMed     Abstract available

  91. NICASTRO N, Malpetti M, Mak E, Williams GB, et al
    Gray matter changes related to microglial activation in Alzheimer's disease.
    Neurobiol Aging. 2020;94:236-242.
    PubMed     Abstract available

  92. CHANDRA A, Farrell C, Wilson H, Dervenoulas G, et al
    Aquaporin-4 polymorphisms predict amyloid burden and clinical outcome in the Alzheimer's disease spectrum.
    Neurobiol Aging. 2020;97:1-9.
    PubMed     Abstract available

  93. ELMAN JA, Vuoksimaa E, Franz CE, Kremen WS, et al
    Degree of cognitive impairment does not signify early versus late mild cognitive impairment: confirmation based on Alzheimer's disease polygenic risk.
    Neurobiol Aging. 2020;94:149-153.
    PubMed     Abstract available

  94. VANZULLI I, Papanikolaou M, De-La-Rocha IC, Pieropan F, et al
    Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease.
    Neurobiol Aging. 2020;94:130-139.
    PubMed     Abstract available

  95. BAUER CE, Brown CA, Gold BT
    Education does not protect cognitive function from brain pathology in the ADNI 2 cohort.
    Neurobiol Aging. 2020;90:147-149.
    PubMed     Abstract available

    May 2020
  96. SUGARMAN MA, Zetterberg H, Blennow K, Tripodis Y, et al
    A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease.
    Neurobiol Aging. 2020;94:60-70.
    PubMed     Abstract available

  97. SIVERA R, Capet N, Manera V, Fabre R, et al
    Voxel-based assessments of treatment effects on longitudinal brain changes in the Multidomain Alzheimer Preventive Trial cohort.
    Neurobiol Aging. 2020;94:50-59.
    PubMed     Abstract available

  98. DICKS E, van der Flier WM, Scheltens P, Barkhof F, et al
    Single-subject gray matter networks predict future cortical atrophy in preclinical Alzheimer's disease.
    Neurobiol Aging. 2020;94:71-80.
    PubMed     Abstract available

  99. DONG JW, Jelescu IO, Ades-Aron B, Novikov DS, et al
    Diffusion MRI biomarkers of white matter microstructure vary nonmonotonically with increasing cerebral amyloid deposition.
    Neurobiol Aging. 2020;89:118-128.
    PubMed     Abstract available

  100. JIAO B, Zhou L, Zhou Y, Weng L, et al
    Identification of expanded repeats in NOTCH2NLC in neurodegenerative dementias.
    Neurobiol Aging. 2020;89:142.
    PubMed     Abstract available

  101. MARIZZONI M, Ferrari C, Babiloni C, Albani D, et al
    CSF cutoffs for MCI due to AD depend on APOEepsilon4 carrier status.
    Neurobiol Aging. 2020;89:55-62.
    PubMed     Abstract available

  102. VAN OLST L, Verhaege D, Franssen M, Kamermans A, et al
    Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model.
    Neurobiol Aging. 2020;89:89-98.
    PubMed     Abstract available

  103. HAMANO T, Shirafuji N, Yen SH, Yoshida H, et al
    Rho-kinase ROCK inhibitors reduce oligomeric tau protein.
    Neurobiol Aging. 2020;89:41-54.
    PubMed     Abstract available

    April 2020
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    Identification of a novel PSEN1 mutation (Leu232Pro) in a Korean patient with early-onset Alzheimer's disease and a family history of dementia.
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    March 2017
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    PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis.
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    Different trajectories of decline for global form and global motion processing in aging, mild cognitive impairment and Alzheimer's disease.
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    Currents of memory: recent progress, translational challenges, and ethical considerations in fornix deep brain stimulation trials for Alzheimer's disease.
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    Selective deletion of apolipoprotein E in astrocytes ameliorates the spatial learning and memory deficits in Alzheimer's disease (APP/PS1) mice by inhibiting TGF-beta/Smad2/STAT3 signaling.
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    Maintenance of membrane organization in the aging mouse brain as the determining factor for preventing receptor dysfunction and for improving response to anti-Alzheimer treatments.
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    November 2016
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    Administrations of human adult ischemia-tolerant mesenchymal stem cells and factors reduce amyloid beta pathology in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2016;51:83-96.
    PubMed     Abstract available

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    What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease.
    Neurobiol Aging. 2016 Nov 21. pii: S0197-4580(16)30294.
    PubMed     Abstract available

  506. ESKILDSEN SF, Gyldensted L, Nagenthiraja K, Nielsen RB, et al
    Increased cortical capillary transit time heterogeneity in Alzheimer's disease: a DSC-MRI perfusion study.
    Neurobiol Aging. 2016;50:107-118.
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  507. VIJVERBERG EG, Tijms BM, Dopp J, Hong YJ, et al
    Gray matter network differences between behavioral variant frontotemporal dementia and Alzheimer's disease.
    Neurobiol Aging. 2016;50:77-86.
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  508. ZAHRATKA JA, Shao Y, Shaw M, Todd K, et al
    Regulatory region genetic variation is associated with FYN expression in Alzheimer's disease.
    Neurobiol Aging. 2016;51:43-53.
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    October 2016
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    PGE2-EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2016;50:13-24.
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  510. SHEA YF, Chan AO, Chu LW, Lee SC, et al
    Novel presenilin 1 mutation (p.F386I) in a Chinese family with early-onset Alzheimer's disease.
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  511. ZHAN Y, Zheng H, Wang C, Rong Z, et al
    A novel presenilin 1 mutation (F388L) identified in a Chinese family with early-onset Alzheimer's disease.
    Neurobiol Aging. 2016 Oct 15. pii: S0197-4580(16)30250.
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  512. TOURNISSAC M, Vandal M, Francois A, Planel E, et al
    Old age potentiates cold-induced tau phosphorylation: linking thermoregulatory deficit with Alzheimer's disease.
    Neurobiol Aging. 2016;50:25-29.
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  513. NATELSON LOVE M, Clark DG, Cochran JN, Den Beste KA, et al
    Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease.
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  514. PICHLER S, Gu W, Hartl D, Gasparoni G, et al
    The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster.
    Neurobiol Aging. 2016 Oct 3. pii: S0197-4580(16)30233.
    PubMed     Abstract available

    September 2016
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    Medial temporal lobe subregional morphometry using high resolution MRI in Alzheimer's disease.
    Neurobiol Aging. 2016 Sep 30. pii: S0197-4580(16)30224.
    PubMed     Abstract available

  516. BARBER IS, Braae A, Clement N, Patel T, et al
    Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array.
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  517. MARIN R, Fabelo N, Martin V, Garcia-Esparcia P, et al
    Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by Alzheimer's and Parkinson's diseases.
    Neurobiol Aging. 2016;49:52-59.
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  518. ROSHCHUPKIN GV, Adams HH, van der Lee SJ, Vernooij MW, et al
    Fine-mapping the effects of Alzheimer's disease risk loci on brain morphology.
    Neurobiol Aging. 2016;48:204-211.
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    August 2016
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    Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease.
    Neurobiol Aging. 2016;48:135-142.
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  520. BABILONI C, Del Percio C, Caroli A, Salvatore E, et al
    Cortical sources of resting state EEG rhythms are related to brain hypometabolism in subjects with Alzheimer's disease: an EEG-PET study.
    Neurobiol Aging. 2016;48:122-134.
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  521. KOLBE K, Bukhari H, Loosse C, Leonhardt G, et al
    Extensive nuclear sphere generation in the human Alzheimer's brain.
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  522. POTTIER C, Ravenscroft TA, Brown PH, Finch NA, et al
    TYROBP genetic variants in early-onset Alzheimer's disease.
    Neurobiol Aging. 2016 Aug 8. pii: S0197-4580(16)30165.
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    May 2016
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    Dopaminergic neurotransmission dysfunction induced by amyloid-beta transforms cortical long-term potentiation into long-term depression and produces memory impairment.
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    Association of genetic risk factors with cognitive decline: the PATH through life project.
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  525. BRANGER P, Arenaza-Urquijo EM, Tomadesso C, Mezenge F, et al
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  526. OTT S, Vishnivetskaya A, Malmendal A, Crowther DC, et al
    Metabolic changes may precede proteostatic dysfunction in a Drosophila model of amyloid beta peptide toxicity.
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    April 2016
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    Differential effects of amyloid-beta 1-40 and 1-42 fibrils on 5-HT1A serotonin receptors in rat brain.
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    March 2016
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  532. RAMIREZ LM, Goukasian N, Porat S, Hwang KS, et al
    Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy.
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  533. MORRIS JK, Vidoni ED, Mahnken JD, Montgomery RN, et al
    Cognitively impaired elderly exhibit insulin resistance and no memory improvement with infused insulin.
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    February 2016
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    Distinctive pathological mechanisms involved in primary progressive aphasias.
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  535. GISPERT JD, Monte GC, Falcon C, Tucholka A, et al
    CSF YKL-40 and pTau181 are related to different cerebral morphometric patterns in early AD.
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  536. TEN KATE M, Sanz-Arigita EJ, Tijms BM, Wink AM, et al
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    Sulforaphane exerts its anti-inflammatory effect against amyloid-beta peptide via STAT-1 dephosphorylation and activation of Nrf2/HO-1 cascade in human THP-1 macrophages.
    Neurobiol Aging. 2016;38:1-10.
    PubMed     Abstract available

    January 2016
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    Neuronal network activity in the hippocampus of tau transgenic (Tg4510) mice.
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    MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials.
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    Evaluating pathogenic dementia variants in posterior cortical atrophy.
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    Association of APOE with tau-tangle pathology with and without beta-amyloid.
    Neurobiol Aging. 2016;37:19-25.
    PubMed     Abstract available

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