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Articles published in J Neurochem

Retrieve available abstracts of 55 articles:
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Single Articles

    November 2022
  1. GARCIA-SEGURA ME, Durainayagam BR, Liggi S, Graca G, et al
    Pathway-based integration of multi-omics data reveals lipidomics alterations validated in an Alzheimer s Disease mouse model and risk loci carriers.
    J Neurochem. 2022 Nov 3. doi: 10.1111/jnc.15719.
    PubMed     Abstract available

  2. SEPULVEDA J, Luo N, Nelson M, Ng CAS, et al
    Independent APOE4 knock-in mouse models display reduced brain APOE protein, altered neuroinflammation, and simplification of dendritic spines.
    J Neurochem. 2022;163:247-259.
    PubMed     Abstract available

    October 2022
  3. MUKHERJEE S, Dubois C, Perez K, Varghese S, et al
    Quantitative proteomics of tau and Abeta in detergent fractions from Alzheimer's disease brains.
    J Neurochem. 2022 Oct 21. doi: 10.1111/jnc.15713.
    PubMed     Abstract available

    Serine racemase modulation for improving brain insulin resistance: An Editorial Highlight for "Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid-beta oligomers": An Editorial Highlight for "Deletion of serine racema
    J Neurochem. 2022;163:6-7.
    PubMed     Abstract available

  5. ZHOU J, Zhang Z, Yang Y, Liao F, et al
    Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid-beta oligomers.
    J Neurochem. 2022;163:8-25.
    PubMed     Abstract available

    September 2022
  6. VAZ M, Martins TS, Henriques AG
    Extracellular vesicles in the study of Alzheimer's and Parkinson's diseases: methodologies applied from cells to biofluids.
    J Neurochem. 2022 Sep 26. doi: 10.1111/jnc.15697.
    PubMed     Abstract available

  7. MICHNO W, Koutarapu S, Camacho R, Toomey C, et al
    Chemical traits of cerebral amyloid angiopathy in familial British-, Danish- and non-Alzheimer's dementias.
    J Neurochem. 2022 Sep 14. doi: 10.1111/jnc.15694.
    PubMed     Abstract available

    August 2022
  8. GALGANI A, Vergallo A, Campese N, Lombardo F, et al
    Biological determinants of blood-based cytokines in the Alzheimer's Disease clinical continuum.
    J Neurochem. 2022 Aug 11. doi: 10.1111/jnc.15686.
    PubMed     Abstract available

  9. DEVINA T, Wong YH, Hsiao CW, Li YJ, et al
    Endoplasmic reticulum stress induces Alzheimer's disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein.
    J Neurochem. 2022 Aug 9. doi: 10.1111/jnc.15687.
    PubMed     Abstract available

  10. DI RISOLA D, Ricci D, Marrocco I, Giamogante F, et al
    ERp57 chaperon protein protects neuronal cells from Abeta-induced toxicity.
    J Neurochem. 2022;162:322-336.
    PubMed     Abstract available

    July 2022
  11. PEDRINI S, Doecke JD, Hone E, Wang P, et al
    Plasma high-density lipoprotein cargo is altered in Alzheimer's disease and is associated with regional brain volume.
    J Neurochem. 2022 Jul 30. doi: 10.1111/jnc.15681.
    PubMed     Abstract available

    May 2022
  12. QIN YR, Ma CQ, Jiang JH, Wang DP, et al
    Artesunate restores mitochondrial fusion-fission dynamics and alleviates neuronal injury in Alzheimer's disease models.
    J Neurochem. 2022 May 21. doi: 10.1111/jnc.15620.
    PubMed     Abstract available

  13. YU ZY, Yi X, Wang YR, Zeng GH, et al
    Inhibiting alpha1-adrenergic receptor signaling pathway ameliorates AD-type pathologies and behavioral deficits in APPswe/PS1 mouse model.
    J Neurochem. 2022;161:293-307.
    PubMed     Abstract available

  14. LOURENCO MV, Hausmann L
    Editorial: Honouring John Hardy - A true pioneer in research.
    J Neurochem. 2022;161:316-319.
    PubMed     Abstract available

    April 2022
  15. TURATI J, Rudi J, Beauquis J, Carniglia L, et al
    A metabotropic glutamate receptor 3 (mGlu3R) isoform playing neurodegenerative roles in astrocytes is prematurely up-regulated in an Alzheimer's model.
    J Neurochem. 2022 Apr 11. doi: 10.1111/jnc.15610.
    PubMed     Abstract available

  16. ZIFF OJ, Ashton NJ, Mehta PR, Brown R, et al
    Amyloid processing in COVID-19-associated neurological syndromes.
    J Neurochem. 2022;161:146-157.
    PubMed     Abstract available

    March 2022
  17. KLAFKI HW, Wirths O, Mollenhauer B, Liepold T, et al
    Detection and quantification of Abeta-3-40 (APP669-711) in cerebrospinal fluid.
    J Neurochem. 2022;160:578-589.
    PubMed     Abstract available

    February 2022
  18. MICHNO W, Wehrli PM, Koutarapu S, Marsching C, et al
    Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging.
    J Neurochem. 2022;160:482-498.
    PubMed     Abstract available

    January 2022
  19. LOPES CR, Amaral IM, Pereira MF, Lopes JP, et al
    Impact of blunting astrocyte activity on hippocampal synaptic plasticity in a mouse model of early Alzheimer's disease based on amyloid-beta peptide exposure.
    J Neurochem. 2022 Jan 19. doi: 10.1111/jnc.15575.
    PubMed     Abstract available

    December 2021
  20. KASICA NP, Zhou X, Yang Q, Wang X, et al
    Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer's disease model mice.
    J Neurochem. 2021 Dec 21. doi: 10.1111/jnc.15562.
    PubMed     Abstract available

  21. KUMAR A, Fontana IC, Nordberg A
    Reactive astrogliosis: A friend or foe in the pathogenesis of Alzheimer's disease.
    J Neurochem. 2021 Dec 20. doi: 10.1111/jnc.15565.
    PubMed     Abstract available

  22. FARUK MO, Tsuboi D, Yamahashi Y, Funahashi Y, et al
    Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning.
    J Neurochem. 2021 Dec 8. doi: 10.1111/jnc.15555.
    PubMed     Abstract available

    November 2021
  23. MA T
    Roles of eukaryotic elongation factor 2 kinase (eEF2K) in neuronal plasticity, cognition, and Alzheimer's disease.
    J Neurochem. 2021 Nov 19. doi: 10.1111/jnc.15541.
    PubMed     Abstract available

  24. MATUSZYK MM, Garwood CJ, Ferraiuolo L, Simpson JE, et al
    Biological and Methodological Complexities of Beta-Amyloid Peptide; Implications for Alzheimer's Disease Research.
    J Neurochem. 2021 Nov 12. doi: 10.1111/jnc.15538.
    PubMed     Abstract available

  25. ZULIANI G, Trentini A, Brombo G, Rosta V, et al
    Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment.
    J Neurochem. 2021;159:629-637.
    PubMed     Abstract available

    October 2021
    Preface: Mass spectrometry in Alzheimer disease: This is the Preface for the special issue "Mass Spectrometry in Alzheimer Disease".
    J Neurochem. 2021;159:207-210.
    PubMed     Abstract available

  27. GKANATSIOU E, Nilsson J, Toomey CE, Vrillon A, et al
    Amyloid pathology and synaptic loss in pathological aging.
    J Neurochem. 2021;159:258-272.
    PubMed     Abstract available

    September 2021
  28. JAKARIA M, Belaidi AA, Bush AI, Ayton S, et al
    Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease.
    J Neurochem. 2021 Sep 23. doi: 10.1111/jnc.15519.
    PubMed     Abstract available

  29. GEULA C, Dunlop SR, Ayala I, Kawles AS, et al
    Basal forebrain cholinergic system in the dementias: Vulnerability, resilience, and resistance.
    J Neurochem. 2021;158:1394-1411.
    PubMed     Abstract available

    July 2021
  30. MICHNO W, Blennow K, Zetterberg H, Brinkmalm G, et al
    Refining the amyloid beta peptide and oligomer fingerprint ambiguities in Alzheimer's disease: mass spectrometric molecular characterization in brain, CSF, blood and plasma.
    J Neurochem. 2021 Jul 10. doi: 10.1111/jnc.15466.
    PubMed     Abstract available

  31. KORECKA M, Shaw LM
    Mass spectrometry-based methods for robust measurement of Alzheimer's Disease biomarkers in biological fluids.
    J Neurochem. 2021 Jul 10. doi: 10.1111/jnc.15465.
    PubMed     Abstract available

  32. Retraction: Clinical trials in Alzheimer's disease': immunotherapy approaches.
    J Neurochem. 2021 Jul 6. doi: 10.1111/jnc.15435.
    PubMed     Abstract available

  33. WANG XM, Zeng P, Fang YY, Zhang T, et al
    Progranulin in neurodegenerative dementia.
    J Neurochem. 2021;158:119-137.
    PubMed     Abstract available

  34. XU L, Tian S, Peng X, Hua Y, et al
    Clusterin inhibits Abeta42 aggregation through a "strawberry model" as detected by FRET-FCS.
    J Neurochem. 2021;158:444-454.
    PubMed     Abstract available

    June 2021
  35. CORTES-GOMEZ MA, Llorens-Alvarez E, Alom J, Del Ser T, et al
    Tau phosphorylation by glycogen synthase kinase 3beta modulates enzyme acetylcholinesterase expression.
    J Neurochem. 2021;157:2091-2105.
    PubMed     Abstract available

    May 2021
  36. LI KY, Xiang XJ, Song L, Chen J, et al
    Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
    J Neurochem. 2021;157:1351-1365.
    PubMed     Abstract available

    April 2021
  37. LEE-LIU D, Gonzalez-Billault C
    Neuron-intrinsic origin of hyperexcitability during early pathogenesis of Alzheimer's disease: An Editorial Highlight for "Hippocampal hyperactivity in a rat model of Alzheimer's disease" on https://doi.org/10.1111/jnc.15323.
    J Neurochem. 2021 Apr 28. doi: 10.1111/jnc.15248.
    PubMed     Abstract available

  38. SUN L, Bhawal R, Xu H, Chen H, et al
    The human brain acetylome reveals that decreased acetylation of mitochondrial proteins associates with Alzheimer's disease.
    J Neurochem. 2021 Apr 27. doi: 10.1111/jnc.15377.
    PubMed     Abstract available

  39. VAN DER VELPEN V, Rosenberg N, Maillard V, Teav T, et al
    Sex-specific alterations in NAD+ metabolism in triple transgenic Alzheimer's disease mouse brain assessed by quantitative targeted liquid chromatography - mass spectrometry.
    J Neurochem. 2021 Apr 8. doi: 10.1111/jnc.15362.
    PubMed     Abstract available

    March 2021
  40. BUTLER CA, Thornton P, Brown GC
    CD33M inhibits microglial phagocytosis, migration and proliferation, but the Alzheimer's disease-protective variant CD33m stimulates phagocytosis and proliferation, and inhibits adhesion.
    J Neurochem. 2021 Mar 15. doi: 10.1111/jnc.15349.
    PubMed     Abstract available

  41. CHEN H, Cross AC, Thakkar A, Xu H, et al
    Selective linkage of mitochondrial enzymes to intracellular calcium stores differs between human-induced pluripotent stem cells, neural stem cells, and neurons.
    J Neurochem. 2021;156:867-879.
    PubMed     Abstract available

    February 2021
  42. SOSULINA L, Mittag M, Geis HR, Hoffmann K, et al
    Hippocampal hyperactivity in a rat model of Alzheimer's disease.
    J Neurochem. 2021 Feb 14. doi: 10.1111/jnc.15323.
    PubMed     Abstract available

  43. ARBER C, Alatza A, Leckey CA, Paterson RW, et al
    Mass spectrometry analysis of tau and amyloid-beta in iPSC-derived models of Alzheimer's disease and dementia.
    J Neurochem. 2021 Feb 4. doi: 10.1111/jnc.15315.
    PubMed     Abstract available

    January 2021
  44. HUANG SJ, Ma YH, Bi YL, Shen XN, et al
    Metabolically healthy obesity and lipids may be protective factors for pathological changes of Alzheimer's disease in cognitively normal adults.
    J Neurochem. 2021 Jan 18. doi: 10.1111/jnc.15306.
    PubMed     Abstract available

  45. GRUNDER G, Cumming P
    Serotonin and amyloid deposition: A link between depression and Alzheimer's disease?: An Editorial Highlight on "Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Abeta production and related pathology in a mouse model of Alzheimer's
    J Neurochem. 2021 Jan 18. doi: 10.1111/jnc.15269.
    PubMed     Abstract available

  46. HARK TJ, Savas JN
    Using stable isotope labeling to advance our understanding of Alzheimer's disease etiology and pathology.
    J Neurochem. 2021 Jan 12. doi: 10.1111/jnc.15298.
    PubMed     Abstract available

    December 2020
  47. HIGHET B, Anekal PV, Ryan B, Murray H, et al
    fISHing with immunohistochemistry for housekeeping gene changes in Alzheimer's disease using an automated quantitative analysis workflow.
    J Neurochem. 2020 Dec 25. doi: 10.1111/jnc.15283.
    PubMed     Abstract available

  48. STOLERO N, Frenkel D
    The Dialog between Neurons and Microglia in Alzheimer's Disease: The Neurotransmitters View.
    J Neurochem. 2020 Dec 12. doi: 10.1111/jnc.15262.
    PubMed     Abstract available

  49. YUEDE CM, Wallace CE, Davis TA, Gardiner WD, et al
    Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Abeta production and related pathology in a mouse model of Alzheimer's disease.
    J Neurochem. 2020 Dec 5. doi: 10.1111/jnc.15260.
    PubMed     Abstract available

    Hippocampal hyperglutamatergic signaling matters: Early targeting glutamate neurotransmission as a preventive strategy in Alzheimer's disease: An Editorial Highlight for "Riluzole attenuates glutamatergic tone and cognitive decline in AbetaPP/PS1 mice
    J Neurochem. 2020 Dec 4. doi: 10.1111/jnc.15238.
    PubMed     Abstract available

  51. LI W, Wu M, Zhang Y, Wei X, et al
    Intermittent fasting promotes adult hippocampal neuronal differentiation by activating GSK-3beta in 3xTg-AD mice.
    J Neurochem. 2020;155:697-713.
    PubMed     Abstract available

    November 2020
  52. LI L, Miao M, Chen J, Liu Z, et al
    Role of Tet2 in modulating neuronal morphology and cognition in a mouse model of Alzheimer's disease.
    J Neurochem. 2020 Nov 9. doi: 10.1111/jnc.15234.
    PubMed     Abstract available

  53. VINKLAROVA L, Schmidt M, Benek O, Kuca K, et al
    Friend or enemy? Review of 17beta-HSD10 and its role in human health or disease.
    J Neurochem. 2020;155:231-249.
    PubMed     Abstract available

    October 2020
  54. LIMEGROVER CS, LeVine H 3rd, Izzo NJ, Yurko R, et al
    Alzheimer's Protection Effect of A673T Mutation May Be Driven by Lower Abeta Oligomer Binding Affinity.
    J Neurochem. 2020 Oct 6. doi: 10.1111/jnc.15212.
    PubMed     Abstract available

    September 2020
  55. GAUNITZ S, Tjernberg LO, Schedin-Weiss S
    The N-glycan profile in cortex and hippocampus is altered in Alzheimer s disease.
    J Neurochem. 2020 Sep 28. doi: 10.1111/jnc.15202.
    PubMed     Abstract available

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