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Articles published in J Neurochem

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Single Articles


    July 2018
  1. GRANGER MW, Liu H, Fowler CF, Blanchard AP, et al
    Distinct disruptions in Land's cycle remodeling of glycerophosphocholines in murine cortex mark symptomatic onset and progression in two Alzheimer's Disease mouse models.
    J Neurochem. 2018 Jul 24. doi: 10.1111/jnc.14560.
    PubMed     Text format     Abstract available


    May 2018
  2. HOPP SC, Bihlmeyer NA, Corradi JP, Vanderburg C, et al
    Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain.
    J Neurochem. 2018 May 28. doi: 10.1111/jnc.14469.
    PubMed     Text format     Abstract available


    April 2018
  3. CALVO-FLORES GUZMAN B, Vinnakota C, Govindpani K, Waldvogel H, et al
    The GABAergic System as a Therapeutic Target for Alzheimer's Disease.
    J Neurochem. 2018 Apr 12. doi: 10.1111/jnc.14345.
    PubMed     Text format     Abstract available


    February 2018
  4. KWAKOWSKY A, Calvo-Flores Guzman B, Pandya M, Turner C, et al
    GABAA receptor subunit expression changes in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus.
    J Neurochem. 2018 Feb 27. doi: 10.1111/jnc.14325.
    PubMed     Text format     Abstract available


    January 2018
  5. GARNER B, Ooi L
    Wnt is here! Could Wnt signalling be promoted to protect against Alzheimer disease?: An Editorial for 'Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20- APP transgenic and wild-type mice' on do
    J Neurochem. 2018 Jan 26. doi: 10.1111/jnc.14276.
    PubMed     Text format     Abstract available


  6. PAN Y, Choy KHC, Marriott PJ, Chai SY, et al
    Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets.
    J Neurochem. 2018;144:81-92.
    PubMed     Text format     Abstract available


    December 2017
  7. NUCERA A, Hachinski V
    Cerebrovascular and alzheimer disease: fellow travellers or partners in crime?
    J Neurochem. 2017 Dec 21. doi: 10.1111/jnc.14283.
    PubMed     Text format     Abstract available


  8. KACZMARCZYK R, Tejera D, Simon BJ, Heneka MT, et al
    Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease.
    J Neurochem. 2017 Dec 21. doi: 10.1111/jnc.14284.
    PubMed     Text format     Abstract available


  9. TAPIA-ROJAS C, Inestrosa NC
    Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20-APP transgenic and wild-type mice.
    J Neurochem. 2017 Dec 14. doi: 10.1111/jnc.14278.
    PubMed     Text format     Abstract available


  10. BRACZYNSKI AK, Schulz JB, Bach JP
    Vaccination strategies in tauopathies and synucleinopathies.
    J Neurochem. 2017;143:467-488.
    PubMed     Text format     Abstract available


  11. KAWANO H, Oyabu K, Yamamoto H, Eto K, et al
    Astrocytes with previous chronic exposure to amyloid beta-peptide fragment 1-40 suppress excitatory synaptic transmission.
    J Neurochem. 2017;143:624-634.
    PubMed     Text format     Abstract available


  12. COLVIN BA, Rogers VA, Kulas JA, Ridgway EA, et al
    The conformational epitope for a new Abeta42 protofibril-selective antibody partially overlaps with the peptide N-terminal region.
    J Neurochem. 2017;143:736-749.
    PubMed     Text format     Abstract available


    November 2017
  13. MOLNAR E
    New tool to tackle Alzheimer's disease: amyloid-beta protofibril-selective antibody AbSL: An Editorial Highlight for 'The conformational epitope for a new Abeta42 protofibril-selective antibody partially overlaps with the peptide N-terminal region' on
    J Neurochem. 2017 Nov 23. doi: 10.1111/jnc.14240.
    PubMed     Text format     Abstract available


  14. KUSAKARI S, Nawa M, Sudo K, Matsuoka M, et al
    Calmodulin-like skin protein protects against spatial learning impairment in a mouse model of Alzheimer disease.
    J Neurochem. 2017 Nov 21. doi: 10.1111/jnc.14258.
    PubMed     Text format     Abstract available


  15. NDAY CM, Eleftheriadou D, Jackson G
    Shared Pathological Pathways of Alzheimer's disease with Specific Comorbidities: Current Perspectives and Interventions.
    J Neurochem. 2017 Nov 21. doi: 10.1111/jnc.14256.
    PubMed     Text format     Abstract available


  16. CHANEY A, Bauer M, Bochicchio D, Smigova A, et al
    Longitudinal investigation of neuroinflammation and metabolite profiles in the APPswe xPS1Deltae9 transgenic mouse model of Alzheimer's disease.
    J Neurochem. 2017 Nov 10. doi: 10.1111/jnc.14251.
    PubMed     Text format     Abstract available


    October 2017
  17. BEHL C, Ziegler C
    Beyond Amyloid - Widening the View on Alzheimer's Disease.
    J Neurochem. 2017 Oct 20. doi: 10.1111/jnc.14137.
    PubMed     Text format     Abstract available


  18. WILLIAM REBECK G, Pak DTS
    A mobile APP for sharing contacts on your cell: An Editorial Highlight for 'The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system' on page 11.
    J Neurochem. 2017;143:9-10.
    PubMed     Text format     Abstract available


  19. SOSA LJ, Caceres A, Dupraz S, Oksdath M, et al
    The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system.
    J Neurochem. 2017;143:11-29.
    PubMed     Text format     Abstract available


    August 2017
  20. ROUBROEKS JAY, Smith RG, van den Hove DLA, Lunnon K, et al
    Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases.
    J Neurochem. 2017 Aug 14. doi: 10.1111/jnc.14148.
    PubMed     Text format     Abstract available


    July 2017
  21. LAI AY, McLaurin J
    Rho-associated protein kinases as therapeutic targets for both vascular and parenchymal pathologies in Alzheimer's disease.
    J Neurochem. 2017 Jul 19. doi: 10.1111/jnc.14130.
    PubMed     Text format     Abstract available


  22. CHENG S, Wani WY, Hottman DA, Jeong A, et al
    Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice.
    J Neurochem. 2017;142:297-304.
    PubMed     Text format     Abstract available


  23. NIGAM SM, Xu S, Kritikou JS, Marosi K, et al
    Exercise and BDNF reduce Abeta production by enhancing alpha-secretase processing of APP.
    J Neurochem. 2017;142:286-296.
    PubMed     Text format     Abstract available


    May 2017
  24. TSE KH, Herrup K
    Re-imagining Alzheimer's disease - the diminishing importance of amyloid and a glimpse of what lies ahead.
    J Neurochem. 2017 May 26. doi: 10.1111/jnc.14079.
    PubMed     Text format     Abstract available


  25. COULSON EJ, Bartlett PF
    An exercise path to preventing Alzheimer's disease: An Editorial Highlight on 'Exercise and BDNF reduce Ab production by enhancing alpha-secretase processing of APP'.
    J Neurochem. 2017 May 18. doi: 10.1111/jnc.14038.
    PubMed     Text format     Abstract available


  26. SILMAN I, Sussman JL
    Recent developments in structural studies on acetylcholinesterase.
    J Neurochem. 2017 May 15. doi: 10.1111/jnc.13992.
    PubMed     Text format     Abstract available


  27. RODRIGUEZ L, Mohamed NV, Desjardins A, Lippe R, et al
    Rab7A regulates tau secretion.
    J Neurochem. 2017;141:592-605.
    PubMed     Text format     Abstract available


    April 2017
  28. ARENDT T, Stieler J, Ueberham U
    Is sporadic Alzheimer's disease a developmental disorder?
    J Neurochem. 2017 Apr 11. doi: 10.1111/jnc.14036.
    PubMed     Text format     Abstract available


    March 2017
  29. PUCHOWICZ MA, Seyfried TN
    Novel ketone body therapy for managing Alzheimer's disease: An Editorial Highlight for Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's diseas
    J Neurochem. 2017 Mar 15. doi: 10.1111/jnc.13979.
    PubMed     Text format     Abstract available


  30. BRANDT R, Bakota L
    Microtubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection.
    J Neurochem. 2017 Mar 7. doi: 10.1111/jnc.14011.
    PubMed     Text format     Abstract available


    February 2017
  31. GRALLE M
    The neuronal insulin receptor in its environment.
    J Neurochem. 2017;140:359-367.
    PubMed     Text format     Abstract available


    January 2017
  32. PAWLOSKY RJ, Kemper MF, Kashiwaya Y, King MT, et al
    Effects of a dietary ketone ester on hippocampal glycolytic and TCA cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.
    J Neurochem. 2017 Jan 18. doi: 10.1111/jnc.13958.
    PubMed     Text format     Abstract available


  33. YAMIN G, Teplow DB
    Pittsburgh Compound-B (PiB) binds amyloid beta-protein protofibrils.
    J Neurochem. 2017;140:210-215.
    PubMed     Text format     Abstract available


    December 2016
  34. WHYTE LS, Lau AA, Hemsley KM, Hopwood JJ, et al
    Endo-lysosomal and autophagic dysfunction: A driving factor in Alzheimer's disease?
    J Neurochem. 2016 Dec 27. doi: 10.1111/jnc.13935.
    PubMed     Text format     Abstract available


  35. SALMINEN A, Kauppinen A, Kaarniranta K
    Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease.
    J Neurochem. 2016 Dec 17. doi: 10.1111/jnc.13932.
    PubMed     Text format     Abstract available


  36. YI B, Sahn JJ, Ardestani PM, Evans AK, et al
    Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuro-inflammation in experimental models of Alzheimer's disease.
    J Neurochem. 2016 Dec 7. doi: 10.1111/jnc.13917.
    PubMed     Text format     Abstract available


    November 2016
  37. ELLISON EM, Abner EL, Lovell MA
    Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease.
    J Neurochem. 2016 Nov 27. doi: 10.1111/jnc.13912.
    PubMed     Text format     Abstract available


    September 2016
  38. IMAMURA O, Arai M, Dateki M, Takishima K, et al
    Donepezil promotes differentiation of neural stem cells into mature oligodendrocytes at the expense of astrogenesis.
    J Neurochem. 2016 Sep 24. doi: 10.1111/jnc.13856.
    PubMed     Text format     Abstract available


  39. MURAMATSU I, Yoshiki H, Uwada J, Masuoka T, et al
    Pharmacological evidence of specific acetylcholine transport in rat cerebral cortex and other brain regions.
    J Neurochem. 2016 Sep 14. doi: 10.1111/jnc.13843.
    PubMed     Text format     Abstract available


    June 2016
  40. URIBE-ARIAS A, Posada-Duque RA, Gonzalez-Billault C, Villegas A, et al
    p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease.
    J Neurochem. 2016 Jun 8. doi: 10.1111/jnc.13697.
    PubMed     Text format     Abstract available


  41. HENDERSON BW, Gentry EG, Rush T, Troncoso JC, et al
    Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-beta levels in brain.
    J Neurochem. 2016 Jun 1. doi: 10.1111/jnc.13688.
    PubMed     Text format     Abstract available


    May 2016
  42. GOLDE TE
    Overcoming translational barriers impeding development of Alzheimer's disease modifying therapies.
    J Neurochem. 2016 May 4. doi: 10.1111/jnc.13583.
    PubMed     Text format     Abstract available


  43. KIM J, Yoon H, Chung DE, Brown JL, et al
    miR-186 is decreased in aged brain and suppresses BACE1 expression.
    J Neurochem. 2016;137:436-45.
    PubMed     Text format     Abstract available


    April 2016
  44. CARLRED L, Michno W, Kaya I, Sjovall P, et al
    Probing Amyloid-beta Pathology in transgenic Alzheimer's disease (tgArcSwe) mice using MALDI Imaging Mass Spectrometry.
    J Neurochem. 2016 Apr 26. doi: 10.1111/jnc.13645.
    PubMed     Text format     Abstract available


  45. VAN WAALWIJK VAN DOORN LJ, Koel-Simmelink MJ, Haussmann U, Klafki H, et al
    Validation of soluble amyloid-beta precursor protein assays as diagnostic CSF biomarkers for neurodegenerative diseases.
    J Neurochem. 2016;137:112-21.
    PubMed     Text format     Abstract available


  46. FALKER C, Hartmann A, Guett I, Dohler F, et al
    Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity.
    J Neurochem. 2016;137:88-100.
    PubMed     Text format     Abstract available


    March 2016
  47. BEN HALIMA S, Siegel G, Rajendran L
    miR-186 in Alzheimer's disease: a big hope for a small RNA?
    J Neurochem. 2016 Mar 30. doi: 10.1111/jnc.13573.
    PubMed     Text format     Abstract available


  48. CAPPAI R
    'From past to future' - deciphering the molecular basis of Alzheimer's disease through the pages of the Journal of Neurochemistry.
    J Neurochem. 2016 Mar 21. doi: 10.1111/jnc.13546.
    PubMed     Text format     Abstract available


  49. MARCIANI DJ
    A retrospective analysis of the Alzheimer's disease vaccine progress - The critical need for new development strategies.
    J Neurochem. 2016 Mar 15. doi: 10.1111/jnc.13608.
    PubMed     Text format     Abstract available


  50. RYAZANTSEVA M, Skobeleva K, Glushankova L, Kaznacheyeva E, et al
    Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    J Neurochem. 2016;136:1085-95.
    PubMed     Text format     Abstract available


    January 2016
  51. SOMAVARAPU AK, Kepp KP
    Loss of stability and hydrophobicity of presenilin 1 mutations causing Alzheimer's Disease.
    J Neurochem. 2016 Jan 12. doi: 10.1111/jnc.13535.
    PubMed     Text format     Abstract available


  52. FREEMAN LC, Ting JP
    The pathogenic role of the inflammasome in neurodegenerative diseases.
    J Neurochem. 2016;136 Suppl 1:29-38.
    PubMed     Text format     Abstract available


    December 2015
  53. LEE TH, Park SH, You MH, Lim JH, et al
    A potential therapeutic effect of Saikosaponin C as a novel dual-target anti-Alzheimer agent.
    J Neurochem. 2015 Dec 28. doi: 10.1111/jnc.13515.
    PubMed     Text format     Abstract available


    November 2015
  54. TANG Y, Peng Y, Liu J, Shi L, et al
    Early inflammation-associated factors blunt sterol regulatory element-binding proteins-1-mediated lipogenesis in high-fat diet-fed APP /PSEN1dE9 mouse model of Alzheimer's disease.
    J Neurochem. 2015 Nov 18. doi: 10.1111/jnc.13437.
    PubMed     Text format     Abstract available


  55. GAO L, Tian M, Zhao HY, Xu QQ, et al
    TrkB Activation by 7, 8-Dihydroxyflavone Increases Synapse AMPA Subunits and Ameliorates Spatial Memory Deficits in a Mouse Model of Alzheimer's Disease.
    J Neurochem. 2015 Nov 18. doi: 10.1111/jnc.13432.
    PubMed     Text format     Abstract available


  56. LEE C, Low CY, Francis PT, Attems J, et al
    An isoform-specific role of FynT tyrosine kinase in Alzheimer's disease.
    J Neurochem. 2015 Nov 12. doi: 10.1111/jnc.13429.
    PubMed     Text format     Abstract available


  57. LIAN H, Zheng H
    Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease.
    J Neurochem. 2015 Nov 6. doi: 10.1111/jnc.13424.
    PubMed     Text format     Abstract available


  58. BELAIDI AA, Bush AI
    Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics.
    J Neurochem. 2015 Nov 6. doi: 10.1111/jnc.13425.
    PubMed     Text format     Abstract available


  59. ZHANG Q, Wu HH, Wang Y, Gu GJ, et al
    Neural stem cell transplantation decreases neuroinflammation in a transgenic mouse model of Alzheimer's disease.
    J Neurochem. 2015 Nov 3. doi: 10.1111/jnc.13413.
    PubMed     Text format     Abstract available


    October 2015
  60. MINTER MR, Taylor JM, Crack PJ
    The contribution of neuro-inflammation to amyloid toxicity in Alzheimer's disease.
    J Neurochem. 2015 Oct 28. doi: 10.1111/jnc.13411.
    PubMed     Text format     Abstract available


  61. ISHIKI A, Kamada M, Kawamura Y, Terao C, et al
    Glial fibrillar acidic protein in the cerebrospinal fluid of Alzheimer's disease, dementia with Lewy bodies and frontotemporal lobar degeneration.
    J Neurochem. 2015 Oct 20. doi: 10.1111/jnc.13399.
    PubMed     Text format     Abstract available


  62. WHITCOMB DJ, Molnar E
    Is riluzole a new drug for Alzheimer's disease?
    J Neurochem. 2015;135:207-9.
    PubMed     Text format     Abstract available


  63. COULSON EJ, Andersen OM
    The A-B-C for SORting APP.
    J Neurochem. 2015;135:1-3.
    PubMed     Text format     Abstract available


  64. CERVELLATI C, Trentini A, Romani A, Bellini T, et al
    Serum paraoxonase and arylesterase activities of paraoxonase-1 (PON-1), mild cognitive impairment, and 2-year conversion to dementia: A pilot study.
    J Neurochem. 2015;135:395-401.
    PubMed     Text format     Abstract available


  65. HUNSBERGER HC, Weitzner DS, Rudy CC, Hickman JE, et al
    Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression.
    J Neurochem. 2015;135:381-94.
    PubMed     Text format     Abstract available


  66. XIE C, Soeda Y, Shinzaki Y, In Y, et al
    Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau.
    J Neurochem. 2015;135:19-26.
    PubMed     Text format     Abstract available


  67. HERMEY G, Schmidt N, Bluhm B, Mensching D, et al
    SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.
    J Neurochem. 2015;135:60-75.
    PubMed     Text format     Abstract available


    September 2015
  68. SLEMMON JR, Shapiro A, Mercken M, Streffer J, et al
    Impact of cerebrospinal fluid matrix on the detection of Alzheimer's disease with Abeta42 and influence of disease on the total-Abeta42/Abeta40 ratio.
    J Neurochem. 2015 Sep 1. doi: 10.1111/jnc.13297.
    PubMed     Text format     Abstract available


  69. BAGLIETTO-VARGAS D, Chen Y, Suh D, Ager RR, et al
    Short-term modern life-like stress exacerbates Abeta-pathology and synapse loss in 3xTg-AD mice.
    J Neurochem. 2015;134:915-26.
    PubMed     Text format     Abstract available


  70. SUN LH, Ban T, Liu CD, Chen QX, et al
    Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation.
    J Neurochem. 2015;134:1139-51.
    PubMed     Text format     Abstract available


  71. SANTHANAM AV, d'Uscio LV, He T, Das P, et al
    Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.
    J Neurochem. 2015;134:1129-38.
    PubMed     Text format     Abstract available


  72. DE JAGER M, Drukarch B, Hofstee M, Breve J, et al
    Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity.
    J Neurochem. 2015;134:1116-28.
    PubMed     Text format     Abstract available


  73. AKHTER R, Sanphui P, Das H, Saha P, et al
    The regulation of p53 up-regulated modulator of apoptosis by JNK/c-Jun pathway in beta-amyloid-induced neuron death.
    J Neurochem. 2015;134:1091-103.
    PubMed     Text format     Abstract available


    August 2015
  74. IMAMURA O, Arai M, Dateki M, Toru O, et al
    Nicotinic acetylcholine receptors mediate donepezil-induced oligodendrocyte differentiation.
    J Neurochem. 2015 Aug 28. doi: 10.1111/jnc.13294.
    PubMed     Text format     Abstract available


  75. JI B, Chen CJ, Bando K, Ashino H, et al
    Distinct Binding of Amyloid Imaging Ligands to Unique Amyloid-beta Deposited in the Presubiculum of Alzheimer's Disease.
    J Neurochem. 2015 Aug 28. doi: 10.1111/jnc.13293.
    PubMed     Text format     Abstract available


    July 2015
  76. MARCELLO E, Gardoni F, Di Luca M
    Alzheimer's disease and modern lifestyle: what is the role of stress?
    J Neurochem. 2015 Jul 23. doi: 10.1111/jnc.13210.
    PubMed     Text format     Abstract available


  77. POSADA-DUQUE RA, Lopez-Tobon A, Piedrahita D, Gonzalez-Billault C, et al
    p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing.
    J Neurochem. 2015;134:354-70.
    PubMed     Text format     Abstract available


    June 2015
  78. BRUGGINK KA, Kuiperij HB, Gloerich J, Otte-Holler I, et al
    Dickkopf-related protein 3 is a potential Abeta-associated protein in Alzheimer's Disease.
    J Neurochem. 2015 Jun 27. doi: 10.1111/jnc.13216.
    PubMed     Text format     Abstract available


  79. QUAN X, Yue W, Luo Y, Cao J, et al
    The protein arginine methyltransferase PRMT5 regulates Abeta-induced toxicity in human cell and Caenorhabditis elegans models of Alzheimer disease.
    J Neurochem. 2015 Jun 18. doi: 10.1111/jnc.13191.
    PubMed     Text format     Abstract available


    April 2015
  80. LIU XY, Li HL, Su JB, Ding FH, et al
    Regulation of RAGE splicing by hnRNP A1 and Tra2beta-1 and its potential role in AD pathogenesis.
    J Neurochem. 2015;133:187-98.
    PubMed     Text format     Abstract available


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