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  Alzheimer's Disease

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Articles published in Neurochem Res

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Single Articles

    March 2024
  1. XIAO X, Rui Y, Jin Y, Chen M, et al
    Relationship of Sleep Disorder with Neurodegenerative and Psychiatric Diseases: An Updated Review.
    Neurochem Res. 2024;49:568-582.
    PubMed     Abstract available

    February 2024
  2. ZHANG LJ, Zhang HZ, Liu YW, Tang M, et al
    Sulphated Fucooligosaccharide from Sargassum Horneri: Structural Analysis and Anti-Alzheimer Activity.
    Neurochem Res. 2024 Feb 2. doi: 10.1007/s11064-024-04107.
    PubMed     Abstract available

  3. ALLNUTT MA, Matera KM
    Stabilization and Reduced Cytotoxicity of Amyloid Beta Aggregates in the Presence of Catechol Neurotransmitters.
    Neurochem Res. 2024;49:379-387.
    PubMed     Abstract available

  4. DHALIWAL N, Dhaliwal J, Chopra K
    7, 8-dihydroxyflavone Ameliorates Cholinergic Dysfunction, Inflammation, Oxidative Stress, and Apoptosis in a Rat Model of Vascular Dementia.
    Neurochem Res. 2024 Feb 1. doi: 10.1007/s11064-023-04090.
    PubMed     Abstract available

    January 2024
  5. LIU Y, Meng XK, Shao WZ, Liu YQ, et al
    miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in the Early Stages of Alzheimer's Disease: The Anti-Neurodegenerative Effect of Treadmill Exercise.
    Neurochem Res. 2024 Jan 30. doi: 10.1007/s11064-024-04108.
    PubMed     Abstract available

  6. TAKANO-KAWABE K, Matoba K, Nakamura Y, Moriyama M, et al
    Low Density Lipoprotein Receptor-related Protein 2 Expression and Function in Cultured Astrocytes and Microglia.
    Neurochem Res. 2024;49:199-211.
    PubMed     Abstract available

  7. NADERI S, Motamedi F, Pourbadie HG, Rafiei S, et al
    Neuroprotective Effects of Ferrostatin and Necrostatin Against Entorhinal Amyloidopathy-Induced Electrophysiological Alterations Mediated by voltage-gated Ca(2+) Channels in the Dentate Gyrus Granular Cells.
    Neurochem Res. 2024;49:99-116.
    PubMed     Abstract available

    November 2023
  8. ZHAN Q, Kong F, Shao S, Zhang B, et al
    Pathogenesis of Depression in Alzheimer's Disease.
    Neurochem Res. 2023 Nov 28. doi: 10.1007/s11064-023-04061.
    PubMed     Abstract available

    October 2023
  9. SASIDHARAN R, Mohanan R, Kukreti N, Raj P, et al
    MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer's Disease.
    Neurochem Res. 2023 Oct 9. doi: 10.1007/s11064-023-04031.
    PubMed     Abstract available

    September 2023
  10. WU Z, Tang W, Ibrahim FEEM, Chen X, et al
    Abeta Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
    Neurochem Res. 2023;48:2881-2894.
    PubMed     Abstract available

  11. ASGHAR H, Ahmed T
    Comparative Study of Time-Dependent Aluminum Exposure and Post-Exposure Recovery Shows Better Improvement in Synaptic Changes and Neuronal Pathology in Rat Brain After Short-Term Exposure.
    Neurochem Res. 2023;48:2731-2753.
    PubMed     Abstract available

    August 2023
  12. PANG LW, Hamzah S, Tan SLJ, Mah SH, et al
    The Effects and Mechanisms of Xanthones in Alzheimer's Disease: A Systematic Review.
    Neurochem Res. 2023 Aug 14. doi: 10.1007/s11064-023-04005.
    PubMed     Abstract available

    May 2023
  13. ZHOU Y, Wang Y, Wang Y, Chen L, et al
    LncRNA NKILA Exacerbates Alzheimer's Disease Progression by Regulating the FOXA1-Mediated Transcription of TNFAIP1.
    Neurochem Res. 2023 May 23. doi: 10.1007/s11064-023-03944.
    PubMed     Abstract available

    April 2023
  14. SIDDIQUI N, Ali J, Parvez S, Najmi AK, et al
    Neuroprotective Role of DPP-4 Inhibitor Linagliptin Against Neurodegeneration, Neuronal Insulin Resistance and Neuroinflammation Induced by Intracerebroventricular Streptozotocin in Rat Model of Alzheimer's Disease.
    Neurochem Res. 2023 Apr 20. doi: 10.1007/s11064-023-03924.
    PubMed     Abstract available

  15. LIM D, Tapella L, Dematteis G, Talmon M, et al
    Calcineurin Signalling in Astrocytes: From Pathology to Physiology and Control of Neuronal Functions.
    Neurochem Res. 2023;48:1077-1090.
    PubMed     Abstract available

  16. HUFFELS CFM, Middeldorp J, Hol EM
    Ass Pathology and Neuron-Glia Interactions: A Synaptocentric View.
    Neurochem Res. 2023;48:1026-1046.
    PubMed     Abstract available

    February 2023
  17. ZHANG X, Subbanna S, Williams CRO, Canals-Baker S, et al
    Anti-inflammatory Action of BT75, a Novel RARalpha Agonist, in Cultured Microglia and in an Experimental Mouse Model of Alzheimer's Disease.
    Neurochem Res. 2023 Feb 13. doi: 10.1007/s11064-023-03888.
    PubMed     Abstract available

  18. GUO S, Lei Q, Guo H, Yang Q, et al
    Edaravone Attenuates Abeta 1-42-Induced Inflammatory Damage and Ferroptosis in HT22 Cells.
    Neurochem Res. 2023;48:570-578.
    PubMed     Abstract available

  19. SHARMA V, Singh TG, Kaur A, Mannan A, et al
    Brain-Derived Neurotrophic Factor: A Novel Dynamically Regulated Therapeutic Modulator in Neurological Disorders.
    Neurochem Res. 2023;48:317-339.
    PubMed     Abstract available

    November 2022
  20. AL-KURAISHY HM, Al-Gareeb AI, Alsayegh AA, Hakami ZH, et al
    A Potential Link Between Visceral Obesity and Risk of Alzheimer's Disease.
    Neurochem Res. 2022 Nov 21. doi: 10.1007/s11064-022-03817.
    PubMed     Abstract available

  21. LIU M, Lian B, Lan Z, Sun H, et al
    Transcriptomic Profile Identifies Hippocampal Sgk1 as the Key Mediator of Ovarian Estrogenic Regulation on Spatial Learning and Memory and Abeta Accumulation.
    Neurochem Res. 2022;47:3369-3384.
    PubMed     Abstract available

    October 2022
  22. WU Y, Hang Z, Lei T, Du H, et al
    Intestinal Flora Affect Alzheimer's Disease by Regulating Endogenous Hormones.
    Neurochem Res. 2022 Oct 30. pii: 10.1007/s11064-022-03784.
    PubMed     Abstract available

  23. KIRSTEIN M, Cambrils A, Segarra A, Melero A, et al
    Cholinergic Senescence in the Ts65Dn Mouse Model for Down Syndrome.
    Neurochem Res. 2022;47:3076-3092.
    PubMed     Abstract available

    September 2022
  24. SEYEDAGHAMIRI F, Rajabi M, Mohaddes G
    Targeting Novel microRNAs in Developing Novel Alzheimer's Disease Treatments.
    Neurochem Res. 2022 Sep 1. pii: 10.1007/s11064-022-03734.
    PubMed     Abstract available

  25. HAMAGUCHI T, Ono K, Yamada M
    Transmission of Cerebral beta-Amyloidosis Among Individuals.
    Neurochem Res. 2022;47:2469-2477.
    PubMed     Abstract available

  26. NOPPARAT C, Chaopae W, Boontem P, Sopha P, et al
    Melatonin Attenuates High Glucose-Induced Changes in Beta Amyloid Precursor Protein Processing in Human Neuroblastoma Cells.
    Neurochem Res. 2022;47:2568-2579.
    PubMed     Abstract available

    August 2022
  27. BHATIA S, Singh M, Singh T, Singh V, et al
    Scrutinizing the Therapeutic Potential of PROTACs in the Management of Alzheimer's Disease.
    Neurochem Res. 2022 Aug 20. pii: 10.1007/s11064-022-03722.
    PubMed     Abstract available

  28. DE ALMEIDA EJR, Ibrahim HJ, Chitolina Schetinger MR, de Andrade CM, et al
    Modulation of Inflammatory Mediators and Microglial Activation Through Physical Exercise in Alzheimer's and Parkinson's Diseases.
    Neurochem Res. 2022 Aug 13. pii: 10.1007/s11064-022-03713.
    PubMed     Abstract available

  29. LUO JS, Ning JQ, Chen ZY, Li WJ, et al
    The Role of Mitochondrial Quality Control in Cognitive Dysfunction in Diabetes.
    Neurochem Res. 2022;47:2158-2172.
    PubMed     Abstract available

  30. WANG X, Li B, Yu X, Zhou Y, et al
    The Neuroprotective Effect of GM-1 Ganglioside on the Amyloid-Beta-Induced Oxidative Stress in PC-12 Cells Mediated by Nrf-2/ARE Signaling Pathway.
    Neurochem Res. 2022;47:2405-2415.
    PubMed     Abstract available

  31. IBI D, Kondo S, Ohmi A, Kojima Y, et al
    Preventive Effect of Betaine Against Cognitive Impairments in Amyloid beta Peptide-Injected Mice Through Sirtuin1 in Hippocampus.
    Neurochem Res. 2022;47:2333-2344.
    PubMed     Abstract available

    July 2022
  32. KHEZRI MR, Ghasemnejad-Berenji M
    Icariin: A Potential Neuroprotective Agent in Alzheimer's Disease and Parkinson's Disease.
    Neurochem Res. 2022 Jul 8. pii: 10.1007/s11064-022-03667.
    PubMed     Abstract available

    June 2022
  33. CHINO K, Izuo N, Noike H, Uno K, et al
    Shati/Nat8l Overexpression Improves Cognitive Decline by Upregulating Neuronal Trophic Factor in Alzheimer's Disease Model Mice.
    Neurochem Res. 2022 Jun 27. pii: 10.1007/s11064-022-03649.
    PubMed     Abstract available

    May 2022
  34. EL-GANAINY SO, Soliman OA, Ghazy AA, Allam M, et al
    Intranasal Oxytocin Attenuates Cognitive Impairment, beta-Amyloid Burden and Tau Deposition in Female Rats with Alzheimer's Disease: Interplay of ERK1/2/GSK3beta/Caspase-3.
    Neurochem Res. 2022 May 20. pii: 10.1007/s11064-022-03624.
    PubMed     Abstract available

  35. THENMOZHI AJ, Raja TRW, Janakiraman U, Manivasagam T, et al
    Correction to: Neuroprotective Effect of Hesperidin on Aluminium Chloride Induced Alzheimer's Disease in Wistar Rats.
    Neurochem Res. 2022 May 4. pii: 10.1007/s11064-022-03616.

  36. MANDAL PK, Guha Roy R, Samkaria A, Maroon JC, et al
    In Vivo (13)C Magnetic Resonance Spectroscopy for Assessing Brain Biochemistry in Health and Disease.
    Neurochem Res. 2022;47:1183-1201.
    PubMed     Abstract available

  37. ERDOGAN MA, Kirazlar M, Yigitturk G, Erbas O, et al
    Digoxin Exhibits Neuroprotective Properties in a Rat Model of Dementia.
    Neurochem Res. 2022;47:1290-1298.
    PubMed     Abstract available

    April 2022
  38. GHOLIPOUR P, Komaki A, Parsa H, Ramezani M, et al
    Therapeutic Effects of High-Intensity Interval Training Exercise Alone and Its Combination with Ecdysterone Against Amyloid Beta-Induced Rat Model of Alzheimer's Disease: A Behavioral, Biochemical, and Histological Study.
    Neurochem Res. 2022 Apr 29. pii: 10.1007/s11064-022-03603.
    PubMed     Abstract available

    March 2022
  39. SUNKARIA A, Bhardwaj S
    Sleep Disturbance and Alzheimer's Disease: The Glial Connection.
    Neurochem Res. 2022 Mar 18. pii: 10.1007/s11064-022-03578.
    PubMed     Abstract available

  40. NGUYEN TT, Hulme J, Vo TK, Van Vo G, et al
    The Potential Crosstalk Between the Brain and Visceral Adipose Tissue in Alzheimer's Development.
    Neurochem Res. 2022 Mar 17. pii: 10.1007/s11064-022-03569.
    PubMed     Abstract available

  41. MENG S, Wang B, Li W
    CircAXL Knockdown Alleviates Abeta1-42-Induced Neurotoxicity in Alzheimer's Disease via Repressing PDE4A by Releasing miR-1306-5p.
    Neurochem Res. 2022 Mar 1. pii: 10.1007/s11064-022-03563.
    PubMed     Abstract available

    February 2022
  42. FRONZA MG, Sacramento M, Alves D, Pratico D, et al
    1-(7-Chloroquinolin-4-yl)-N-(4-Methoxybenzyl)-5-Methyl-1H-1,2, 3-Triazole-4- carboxamide Reduces Abeta Formation and Tau Phosphorylation in Cellular Models of Alzheimer's Disease.
    Neurochem Res. 2022 Feb 15. pii: 10.1007/s11064-021-03514.
    PubMed     Abstract available

  43. SHARMA VK, Singh TG, Prabhakar NK, Mannan A, et al
    Kynurenine Metabolism and Alzheimer's Disease: The Potential Targets and Approaches.
    Neurochem Res. 2022 Feb 8. pii: 10.1007/s11064-022-03546.
    PubMed     Abstract available

  44. SHUKLA M, Wongchitrat P, Govitrapong P
    A Synopsis of Multitarget Potential Therapeutic Effects of Huperzine A in Diverse Pathologies-Emphasis on Alzheimer's Disease Pathogenesis.
    Neurochem Res. 2022 Feb 5. pii: 10.1007/s11064-022-03530.
    PubMed     Abstract available

    January 2022
  45. POLIS B, Squillario M, Gurevich V, Srikanth KD, et al
    Effects of Chronic Arginase Inhibition with Norvaline on Tau Pathology and Brain Glucose Metabolism in Alzheimer's Disease Mice.
    Neurochem Res. 2022 Jan 31. pii: 10.1007/s11064-021-03519.
    PubMed     Abstract available

  46. YU H, Shi J, Lin Y, Zhang Y, et al
    Icariin Ameliorates Alzheimer's Disease Pathology by Alleviating Myelin Injury in 3 x Tg-AD Mice.
    Neurochem Res. 2022 Jan 17. pii: 10.1007/s11064-021-03507.
    PubMed     Abstract available

    December 2021
  47. LIU M, Zhang X, Wang Y
    Curcumin Alleviates Abeta42-Induced Neuronal Metabolic Dysfunction via the Thrb/SIRT3 Axis and Improves Cognition in APPTG Mice.
    Neurochem Res. 2021;46:3166-3178.
    PubMed     Abstract available

    October 2021
  48. ROE K
    An Alternative Explanation for Alzheimer's Disease and Parkinson's Disease Initiation from Specific Antibiotics, Gut Microbiota Dysbiosis and Neurotoxins.
    Neurochem Res. 2021 Oct 20. pii: 10.1007/s11064-021-03467.
    PubMed     Abstract available

  49. VERKERKE M, Hol EM, Middeldorp J
    Physiological and Pathological Ageing of Astrocytes in the Human Brain.
    Neurochem Res. 2021;46:2662-2675.
    PubMed     Abstract available

    September 2021
  50. WAN T, Fu M, Jiang Y, Jiang W, et al
    Research Progress on Mechanism of Neuroprotective Roles of Apelin-13 in Prevention and Treatment of Alzheimer's Disease.
    Neurochem Res. 2021 Sep 13. pii: 10.1007/s11064-021-03448.
    PubMed     Abstract available

  51. JIANG P, Chen L, Xu J, Liu W, et al
    Neuroprotective Effects of Rhynchophylline Against Abeta1-42-Induced Oxidative Stress, Neurodegeneration, and Memory Impairment Via Nrf2-ARE Activation.
    Neurochem Res. 2021;46:2439-2450.
    PubMed     Abstract available

    August 2021
  52. SHARMA VK, Singh TG, Singh S, Garg N, et al
    Apoptotic Pathways and Alzheimer's Disease: Probing Therapeutic Potential.
    Neurochem Res. 2021 Aug 12. pii: 10.1007/s11064-021-03418.
    PubMed     Abstract available

  53. KAUR D, Behl T, Sehgal A, Singh S, et al
    Multifaceted Alzheimer's Disease: Building a Roadmap for Advancement of Novel Therapies.
    Neurochem Res. 2021 Aug 6. pii: 10.1007/s11064-021-03415.
    PubMed     Abstract available

    May 2021
  54. ELFOULY A, Awny M, Ibrahim MK, Aboelsaad M, et al
    Effects of Long-Acting Testosterone Undecanoate on Behavioral Parameters and Na + , K(+)-ATPase mRNA Expression in Mice with Alzheimer`s Disease.
    Neurochem Res. 2021 May 25. pii: 10.1007/s11064-021-03357.
    PubMed     Abstract available

  55. XIAN-HUI D, Dong-Xue M, Tian-Ci Z, Xiao-Ping H, et al
    The Effect of TCM-Induced HAMP on Key Enzymes in the Hydrolysis of AD Model Cells.
    Neurochem Res. 2021;46:1068-1080.
    PubMed     Abstract available

    April 2021
  56. LEHMANN L, Lo A, Knox KM, Barker-Haliski M, et al
    Alzheimer's Disease and Epilepsy: A Perspective on the Opportunities for Overlapping Therapeutic Innovation.
    Neurochem Res. 2021 Apr 30. pii: 10.1007/s11064-021-03332.
    PubMed     Abstract available

  57. NAZIR S, Anwar F, Saleem U, Ahmad B, et al
    Drotaverine Inhibitor of PDE4: Reverses the Streptozotocin Induced Alzheimer's Disease in Mice.
    Neurochem Res. 2021 Apr 20. pii: 10.1007/s11064-021-03327.
    PubMed     Abstract available

  58. UDDIN MS, Sumsuzzman DM, Jeandet P, Behl T, et al
    Deciphering the Interacting Mechanisms of Circadian Disruption and Alzheimer's Disease.
    Neurochem Res. 2021 Apr 19. pii: 10.1007/s11064-021-03325.
    PubMed     Abstract available

  59. CAO B, Zeng M, Zhang Q, Zhang B, et al
    Amentoflavone Ameliorates Memory Deficits and Abnormal Autophagy in Abeta25-35-Induced Mice by mTOR Signaling.
    Neurochem Res. 2021;46:921-934.
    PubMed     Abstract available

  60. HACIOGLU C, Kar F, Kanbak G
    Ex Vivo Investigation of Bexarotene and Nicotinamide Function as a Protective Agent on Rat Synaptosomes Treated with Abeta(1-42).
    Neurochem Res. 2021;46:804-818.
    PubMed     Abstract available

    March 2021
  61. SALCEDO C, Wagner A, Andersen JV, Vinten KT, et al
    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease.
    Neurochem Res. 2021 Mar 12. pii: 10.1007/s11064-021-03276.
    PubMed     Abstract available

  62. BABAEI P, Eyvani K, Kouhestani S
    Sex-Independent Cognition Improvement in Response to Kaempferol in the Model of Sporadic Alzheimer's Disease.
    Neurochem Res. 2021 Mar 12. pii: 10.1007/s11064-021-03289.
    PubMed     Abstract available

    February 2021
  63. LI J, Xu C, Zhang J, Jin C, et al
    Identification of miRNA-Target Gene Pairs in the Parietal and Frontal Lobes of the Brain in Patients with Alzheimer's Disease Using Bioinformatic Analyses.
    Neurochem Res. 2021 Feb 13. pii: 10.1007/s11064-020-03215.
    PubMed     Abstract available

  64. XU Y, Cheng L, Sun J, Li F, et al
    Hypermethylation of Mitochondrial Cytochrome b and Cytochrome c Oxidase II Genes with Decreased Mitochondrial DNA Copy Numbers in the APP/PS1 Transgenic Mouse Model of Alzheimer's Disease.
    Neurochem Res. 2021 Feb 12. pii: 10.1007/s11064-020-03192.
    PubMed     Abstract available

  65. LIU X, Wang K, Wei X, Xie T, et al
    Interaction of NF-kappaB and Wnt/beta-catenin Signaling Pathways in Alzheimer's Disease and Potential Active Drug Treatments.
    Neurochem Res. 2021 Feb 1. pii: 10.1007/s11064-021-03227.
    PubMed     Abstract available

  66. GAO Y, Zhang J, Li S, Zhang Y, et al
    Cattle Encephalon Glycoside and Ignotin Protects Neurons Against Microglia-Induced Neuroinflammation via Elevating BDNF Expression and Inhibiting TLR4/NF-kappaB Pathway.
    Neurochem Res. 2021;46:326-336.
    PubMed     Abstract available

  67. CHU F, Li K, Li X, Xu L, et al
    Graphene Oxide Ameliorates the Cognitive Impairment Through Inhibiting PI3K/Akt/mTOR Pathway to Induce Autophagy in AD Mouse Model.
    Neurochem Res. 2021;46:309-325.
    PubMed     Abstract available

    January 2021
  68. ALI M, Saleem U, Anwar F, Imran M, et al
    Screening of Synthetic Isoxazolone Derivative Role in Alzheimer's Disease: Computational and Pharmacological Approach.
    Neurochem Res. 2021 Jan 24. pii: 10.1007/s11064-021-03229.
    PubMed     Abstract available

  69. LARANJINHA J, Nunes C, Ledo A, Lourenco C, et al
    The Peculiar Facets of Nitric Oxide as a Cellular Messenger: From Disease-Associated Signaling to the Regulation of Brain Bioenergetics and Neurovascular Coupling.
    Neurochem Res. 2021;46:64-76.
    PubMed     Abstract available

    Antioxidants and Neuron-Astrocyte Interplay in Brain Physiology: Melatonin, a Neighbor to Rely on.
    Neurochem Res. 2021;46:34-50.
    PubMed     Abstract available

    November 2020
  71. BALCAR VJ, Zeman T, Janout V, Janoutova J, et al
    Single Nucleotide Polymorphism rs11136000 of CLU Gene (Clusterin, ApoJ) and the Risk of Late-Onset Alzheimer's Disease in a Central European Population.
    Neurochem Res. 2020 Nov 18. pii: 10.1007/s11064-020-03176.
    PubMed     Abstract available

    Microglia in Alzheimer's Disease: The Role of Stem Cell-Microglia Interaction in Brain Homeostasis.
    Neurochem Res. 2020 Nov 10. pii: 10.1007/s11064-020-03162.
    PubMed     Abstract available

  73. DING Y, Liu H, Cen M, Tao Y, et al
    Rapamycin Ameliorates Cognitive Impairments and Alzheimer's Disease-Like Pathology with Restoring Mitochondrial Abnormality in the Hippocampus of Streptozotocin-Induced Diabetic Mice.
    Neurochem Res. 2020 Nov 2. pii: 10.1007/s11064-020-03160.
    PubMed     Abstract available

    October 2020
  74. ORTIZ CJC, Damasio CM, Pruccoli L, Nadur NF, et al
    Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases.
    Neurochem Res. 2020 Oct 20. pii: 10.1007/s11064-020-03148.
    PubMed     Abstract available

    April 2020
  75. GE Y, Song X, Liu J, Liu C, et al
    The Combined Therapy of Berberine Treatment with lncRNA BACE1-AS Depletion Attenuates Abeta25-35 Induced Neuronal Injury Through Regulating the Expression of miR-132-3p in Neuronal Cells.
    Neurochem Res. 2020;45:741-751.
    PubMed     Abstract available

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