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Articles published in Neurobiol Dis

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Single Articles


    August 2022
  1. MEHTA NH, Suss RA, Dyke JP, Theise ND, et al
    Quantifying cerebrospinal fluid dynamics: A review of human neuroimaging contributions to CSF physiology and neurodegenerative disease.
    Neurobiol Dis. 2022;170:105776.
    PubMed     Abstract available


  2. WILLIAMS ET, Chen X, Otero PA, Moore DJ, et al
    Understanding the contributions of VPS35 and the retromer in neurodegenerative disease.
    Neurobiol Dis. 2022;170:105768.
    PubMed     Abstract available


    July 2022
  3. NORAMBUENA A, Sun X, Wallrabe H, Cao R, et al
    SOD1 mediates lysosome-to-mitochondria communication and its dysregulation by amyloid-beta oligomers.
    Neurobiol Dis. 2022;169:105737.
    PubMed     Abstract available


    June 2022
  4. RAMAMOORTHY K, Yoshimura R, Al-Juburi S, Anandam KY, et al
    Alzheimer's disease is associated with disruption in thiamin transport physiology: A potential role for neuroinflammation.
    Neurobiol Dis. 2022 Jun 21:105799. doi: 10.1016/j.nbd.2022.105799.
    PubMed     Abstract available


  5. JOHNSON AC, Uhlig F, Einwag Z, Cataldo N, et al
    The neuroendocrine stress response impairs hippocampal vascular function and memory in male and female rats.
    Neurobiol Dis. 2022;168:105717.
    PubMed     Abstract available


  6. AMIN J, Erskine D, Donaghy PC, Surendranathan A, et al
    Inflammation in dementia with Lewy bodies.
    Neurobiol Dis. 2022;168:105698.
    PubMed     Abstract available


  7. KORF JM, Ganesh BP, McCullough LD
    Gut dysbiosis and age-related neurological diseases in females.
    Neurobiol Dis. 2022;168:105695.
    PubMed     Abstract available


  8. AHMED MM, Wang AC, Elos M, Chial HJ, et al
    The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice.
    Neurobiol Dis. 2022;168:105694.
    PubMed     Abstract available


  9. TROUTWINE BR, Strope TA, Franczak E, Lysaker CR, et al
    Mitochondrial function and Abeta in Alzheimer's disease postmortem brain.
    Neurobiol Dis. 2022 Jun 3:105781. doi: 10.1016/j.nbd.2022.105781.
    PubMed     Abstract available


    May 2022
  10. ZENG Q, Li K, Luo X, Wang S, et al
    The association of enlarged perivascular space with microglia-related inflammation and Alzheimer's pathology in cognitively normal elderly.
    Neurobiol Dis. 2022 May 13:105755. doi: 10.1016/j.nbd.2022.105755.
    PubMed     Abstract available


  11. LAMPINEN R, Belaya I, Saveleva L, Liddell JR, et al
    Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.
    Neurobiol Dis. 2022;170:105753.
    PubMed     Abstract available


  12. BUHL E, Kim YA, Parsons T, Zhu B, et al
    Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology.
    Neurobiol Dis. 2022 May 12:105752. doi: 10.1016/j.nbd.2022.105752.
    PubMed     Abstract available


  13. MEEKER KL, Butt OH, Gordon BA, Fagan AM, et al
    Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage.
    Neurobiol Dis. 2022;166:105662.
    PubMed     Abstract available


    April 2022
  14. PURIS E, Auriola S, Petralla S, Hartman R, et al
    Altered protein expression of membrane transporters in isolated cerebral microvessels and brain cortex of a rat Alzheimer's disease model.
    Neurobiol Dis. 2022 Apr 23:105741. doi: 10.1016/j.nbd.2022.105741.
    PubMed     Abstract available


  15. FILIPELLO F, Goldsbury C, You SF, Locca A, et al
    Soluble TREM2: Innocent bystander or active player in neurological diseases?
    Neurobiol Dis. 2022;165:105630.
    PubMed     Abstract available


    March 2022
  16. STRAIN JF, Barthelemy N, Horie K, Gordon BA, et al
    CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer's disease.
    Neurobiol Dis. 2022 Mar 28:105714. doi: 10.1016/j.nbd.2022.105714.
    PubMed     Abstract available


  17. KENKHUIS B, Somarakis A, Kleindouwel LRT, van Roon-Mom WMC, et al
    Co-expression patterns of microglia markers Iba1, TMEM119 and P2RY12 in Alzheimer's disease.
    Neurobiol Dis. 2022;167:105684.
    PubMed     Abstract available


  18. MOON HJ, Haroutunian V, Zhao L
    Human apolipoprotein E isoforms are differentially sialylated and the sialic acid moiety in ApoE2 attenuates ApoE2-Abeta interaction and Abeta fibrillation.
    Neurobiol Dis. 2022;164:105631.
    PubMed     Abstract available


    February 2022
  19. GALEA E, Weinstock LD, Larramona-Arcas R, Pybus AF, et al
    Multi-transcriptomic analysis points to early organelle dysfunction in human astrocytes in Alzheimer's disease.
    Neurobiol Dis. 2022 Feb 7:105655. doi: 10.1016/j.nbd.2022.105655.
    PubMed     Abstract available


    December 2021
  20. SZABO MP, Mishra S, Knupp A, Young JE, et al
    The role of Alzheimer's disease risk genes in endolysosomal pathways.
    Neurobiol Dis. 2021;162:105576.
    PubMed     Abstract available


  21. STEPANCHUK AA, Barber PA, Lashley T, Joseph JT, et al
    Quantitative detection of grey and white matter amyloid pathology using a combination of K114 and CRANAD-3 fluorescence.
    Neurobiol Dis. 2021;161:105540.
    PubMed     Abstract available


  22. LIMORENKO G, Lashuel HA
    To target Tau pathologies, we must embrace and reconstruct their complexities.
    Neurobiol Dis. 2021;161:105536.
    PubMed     Abstract available


    November 2021
  23. LIN X, Chen L, Baglietto-Vargas D, Kamalipour P, et al
    Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model.
    Neurobiol Dis. 2021;162:105562.
    PubMed     Abstract available


  24. GONZALEZ S, McHugh TLM, Yang T, Syriani W, et al
    Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage.
    Neurobiol Dis. 2021 Nov 24:105563. doi: 10.1016/j.nbd.2021.105563.
    PubMed     Abstract available


  25. GURDON B, Kaczorowksi C
    Pursuit of precision medicine: Systems biology approaches in Alzheimer's disease mouse models.
    Neurobiol Dis. 2021;161:105558.
    PubMed     Abstract available


  26. BIYONG ESSI F, Cyntia T, Manon L, Vicky C, et al
    Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies.
    Neurobiol Dis. 2021 Nov 1:105542. doi: 10.1016/j.nbd.2021.105542.
    PubMed     Abstract available


  27. FERRER-RAVENTOS P, Beyer K
    Alternative platelet activation pathways and their role in neurodegenerative diseases.
    Neurobiol Dis. 2021;159:105512.
    PubMed     Abstract available


  28. YANGUAS-CASAS N, Torres C, Crespo-Castrillo A, Diaz-Pacheco S, et al
    High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner.
    Neurobiol Dis. 2021;159:105495.
    PubMed     Abstract available


  29. LAROCCA TJ, Cavalier AN, Roberts CM, Lemieux MR, et al
    Amyloid beta acts synergistically as a pro-inflammatory cytokine.
    Neurobiol Dis. 2021;159:105493.
    PubMed     Abstract available


    October 2021
  30. MIYOSHI E, Morabito S, Swarup V
    Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer's disease and related tauopathies.
    Neurobiol Dis. 2021;160:105530.
    PubMed     Abstract available


    September 2021
  31. OCHIAI T, Sano T, Nagayama T, Kubota N, et al
    Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Sep 16:105510. doi: 10.1016/j.nbd.2021.105510.
    PubMed     Abstract available


  32. GRODSTEIN F, Lemos B, Yu L, Klein HU, et al
    The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
    Neurobiol Dis. 2021;157:105428.
    PubMed     Abstract available


    August 2021
  33. FITZ NF, Wang J, Kamboh MI, Koldamova R, et al
    Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease.
    Neurobiol Dis. 2021 Aug 16:105481. doi: 10.1016/j.nbd.2021.105481.
    PubMed     Abstract available


  34. WANG X, Zhou X, Uberseder B, Lee J, et al
    Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer's disease.
    Neurobiol Dis. 2021;158:105463.
    PubMed     Abstract available


  35. HE Q, Jiang L, Zhang Y, Yang H, et al
    Anti-LINGO-1 antibody ameliorates cognitive impairment, promotes adult hippocampal neurogenesis, and increases the abundance of CB1R-rich CCK-GABAergic interneurons in AD mice.
    Neurobiol Dis. 2021;156:105406.
    PubMed     Abstract available


    July 2021
  36. FUSILIER AR, Davis JA, Paul JR, Yates SD, et al
    Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Jul 29:105454. doi: 10.1016/j.nbd.2021.105454.
    PubMed     Abstract available


    June 2021
  37. PAPPOLLA MA, Perry G, Fang X, Zagorski M, et al
    Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease.
    Neurobiol Dis. 2021;156:105403.
    PubMed     Abstract available


    May 2021
  38. ZHANG L, Qin Z, Sharmin F, Lin W, et al
    Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 May 24:105402. doi: 10.1016/j.nbd.2021.105402.
    PubMed     Abstract available


    April 2021
  39. MARQUEZ A, Guernsey LS, Frizzi KE, Cundiff M, et al
    Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy.
    Neurobiol Dis. 2021;151:105273.
    PubMed     Abstract available


  40. TOZZI F, Rutigliano G, Borso M, Falcicchia C, et al
    T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex.
    Neurobiol Dis. 2021;151:105271.
    PubMed     Abstract available


    March 2021
  41. JIANG N, Cupolillo D, Grosjean N, Muller E, et al
    Impaired plasticity of intrinsic excitability in the dentate gyrus alters spike transfer in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Mar 22:105345. doi: 10.1016/j.nbd.2021.105345.
    PubMed     Abstract available


  42. OJO J, Eisenbaum M, Shackleton B, Lynch C, et al
    Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma.
    Neurobiol Dis. 2021;150:105237.
    PubMed     Abstract available


    February 2021
  43. TSAI AP, Lin PB, Dong C, Moutinho M, et al
    INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia.
    Neurobiol Dis. 2021 Feb 22:105303. doi: 10.1016/j.nbd.2021.105303.
    PubMed     Abstract available


  44. BASAK JM, Ferreiro A, Cohen LS, Sheehan PW, et al
    Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021;152:105292.
    PubMed     Abstract available


  45. XUE F, Tian J, Yu C, Du H, et al
    Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5xFAD mice.
    Neurobiol Dis. 2021 Feb 1:105272. doi: 10.1016/j.nbd.2021.105272.
    PubMed     Abstract available


  46. NOORI A, Mezlini AM, Hyman BT, Serrano-Pozo A, et al
    Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration.
    Neurobiol Dis. 2021;149:105225.
    PubMed     Abstract available


    January 2021
  47. ALCANTARA-GONZALEZ D, Chartampila E, Criscuolo C, Scharfman HE, et al
    Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine.
    Neurobiol Dis. 2021 Jan 20:105274. doi: 10.1016/j.nbd.2021.105274.
    PubMed     Abstract available


  48. KOW RL, Strovas TJ, McMillan PJ, Jacobi AM, et al
    Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.
    Neurobiol Dis. 2021;147:105148.
    PubMed     Abstract available


  49. ALCALA-VIDA R, Awada A, Boutillier AL, Merienne K, et al
    Epigenetic mechanisms underlying enhancer modulation of neuronal identity, neuronal activity and neurodegeneration.
    Neurobiol Dis. 2021;147:105155.
    PubMed     Abstract available


  50. LAMBRACHT-WASHINGTON D, Fu M, Hynan LS, Rosenberg RN, et al
    Changes in the brain transcriptome after DNA Abeta42 trimer immunization in a 3xTg-AD mouse model.
    Neurobiol Dis. 2021;148:105221.
    PubMed     Abstract available


    December 2020
  51. CALIO ML, Mosini AC, Marinho DS, Salles GN, et al
    Leptin enhances adult neurogenesis and reduces pathological features in a transgenic mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Dec 7:105219. doi: 10.1016/j.nbd.2020.105219.
    PubMed     Abstract available


  52. PIMENOVA AA, Herbinet M, Gupta I, Machlovi SI, et al
    Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response.
    Neurobiol Dis. 2020 Dec 7:105217. doi: 10.1016/j.nbd.2020.105217.
    PubMed     Abstract available


    November 2020
  53. ANDERSEN JV, Christensen SK, Westi EW, Diaz-delCastillo M, et al
    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Nov 23:105198. doi: 10.1016/j.nbd.2020.105198.
    PubMed     Abstract available


    October 2020
  54. PENTZ R, Iulita MF, Mikutra-Cencora M, Ducatenzeiler A, et al
    A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology.
    Neurobiol Dis. 2020 Oct 29:105150. doi: 10.1016/j.nbd.2020.105150.
    PubMed     Abstract available


  55. MONTALBANO M, McAllen S, Cascio FL, Sengupta U, et al
    TDP-43 and tau oligomers in Alzheimer's disease, amyotrophic lateral sclerosis, and frontotemporal dementia.
    Neurobiol Dis. 2020 Oct 13:105130. doi: 10.1016/j.nbd.2020.105130.
    PubMed     Abstract available


  56. STEPLER KE, Mahoney ER, Kofler J, Hohman TJ, et al
    Inclusion of African American/black adults in a pilot brain proteomics study of Alzheimer's disease.
    Neurobiol Dis. 2020 Oct 10:105129. doi: 10.1016/j.nbd.2020.105129.
    PubMed     Abstract available


    September 2020
  57. EVANS AK, Ardestani P, Yi B, Park HH, et al
    Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease.
    Neurobiol Dis. 2020 Sep 21:105089. doi: 10.1016/j.nbd.2020.105089.
    PubMed     Abstract available


  58. VON SAUCKEN VE, Jay TR, Landreth GE
    The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Sep 2:105072. doi: 10.1016/j.nbd.2020.105072.
    PubMed     Abstract available


    August 2020
  59. AGRAWAL RR, Montesinos J, Larrea D, Area-Gomez E, et al
    The silence of the fats: A mam's story about Alzheimer.
    Neurobiol Dis. 2020 Aug 28:105062. doi: 10.1016/j.nbd.2020.105062.
    PubMed     Abstract available


  60. MULLINS AE, Kam K, Parekh A, Bubu OM, et al
    Obstructive Sleep Apnea and Its Treatment in Aging: Effects on Alzheimer's disease Biomarkers, Cognition, Brain Structure and Neurophysiology.
    Neurobiol Dis. 2020 Aug 26:105054. doi: 10.1016/j.nbd.2020.105054.
    PubMed     Abstract available


  61. CHIASSEU M, Fesharaki A, Saito T, Saido TC, et al
    Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in.
    Neurobiol Dis. 2020 Aug 25:105059. doi: 10.1016/j.nbd.2020.105059.
    PubMed     Abstract available


  62. ZHANG X, Trebak F, Souza LAC, Shi J, et al
    Small RNA modifications in Alzheimer's disease.
    Neurobiol Dis. 2020 Aug 21:105058. doi: 10.1016/j.nbd.2020.105058.
    PubMed     Abstract available


    July 2020
  63. LUCEY BP
    It's complicated: The relationship between sleep and Alzheimer's disease in humans.
    Neurobiol Dis. 2020 Jul 29:105031. doi: 10.1016/j.nbd.2020.105031.
    PubMed     Abstract available


  64. GHALI MGZ, Marchenko V, Yasargil MG, Ghali GZ, et al
    Structure and function of the perivascular fluid compartment and vertebral venous plexus: Illumining a novel theory on mechanisms underlying the pathogenesis of Alzheimer's, cerebral small vessel, and neurodegenerative diseases.
    Neurobiol Dis. 2020 Jul 17:105022. doi: 10.1016/j.nbd.2020.105022.
    PubMed     Abstract available


  65. PLOTKIN SS, Cashman NR
    Passive immunotherapies targeting Abeta and tau in Alzheimer's disease.
    Neurobiol Dis. 2020 Jul 16:105010. doi: 10.1016/j.nbd.2020.105010.
    PubMed     Abstract available


  66. LAU DHW, Paillusson S, Hartopp N, Rupawala H, et al
    Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain.
    Neurobiol Dis. 2020 Jul 16:105020. doi: 10.1016/j.nbd.2020.105020.
    PubMed     Abstract available


    June 2020
  67. NEUNER SM, Tcw J, Goate AM
    Genetic architecture of Alzheimer's disease.
    Neurobiol Dis. 2020 Jun 18:104976. doi: 10.1016/j.nbd.2020.104976.
    PubMed     Abstract available


  68. SCHWABE T, Srinivasan K, Rhinn H
    Shifting paradigms: The central role of microglia in Alzheimer's disease.
    Neurobiol Dis. 2020 Jun 11:104962. doi: 10.1016/j.nbd.2020.104962.
    PubMed     Abstract available


  69. SCHULTZ SA, Strain JF, Adedokun A, Wang Q, et al
    Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease.
    Neurobiol Dis. 2020;142:104960.
    PubMed     Abstract available


  70. PETRUSHINA I, Hovakimyan A, Harahap-Carrillo IS, Davtyan H, et al
    Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials.
    Neurobiol Dis. 2020;139:104823.
    PubMed     Abstract available


  71. DIOUF I, Bush AI, Ayton S
    Cerebrospinal fluid ceruloplasmin levels predict cognitive decline and brain atrophy in people with underlying beta-amyloid pathology.
    Neurobiol Dis. 2020;139:104810.
    PubMed     Abstract available


  72. HSU S, Pimenova AA, Hayes K, Villa JA, et al
    Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2.
    Neurobiol Dis. 2020;139:104817.
    PubMed     Abstract available


  73. BORRECA A, Valeri F, De Luca M, Ernst L, et al
    Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Abeta pathology.
    Neurobiol Dis. 2020;139:104787.
    PubMed     Abstract available


    May 2020
  74. GUERREIRO R, Gibbons E, Tabuas-Pereira M, Kun-Rodrigues C, et al
    Genetic architecture of common non-Alzheimer's disease dementias.
    Neurobiol Dis. 2020 May 18:104946. doi: 10.1016/j.nbd.2020.104946.
    PubMed     Abstract available


  75. PETERS C, Bascunan D, Burgos CF, Bobadilla C, et al
    Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease.
    Neurobiol Dis. 2020 May 17:104938. doi: 10.1016/j.nbd.2020.104938.
    PubMed     Abstract available


  76. PIMENOVA AA, Goate AM
    Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations.
    Neurobiol Dis. 2020;138:104785.
    PubMed     Abstract available


  77. WISNIEWSKI T, Drummond E
    APOE-amyloid interaction: Therapeutic targets.
    Neurobiol Dis. 2020;138:104784.
    PubMed     Abstract available


    April 2020
  78. MAKARAVA N, Chang JC, Molesworth K, Baskakov IV, et al
    Region-specific glial homeostatic signature in prion diseases is replaced by a uniform neuroinflammation signature, common for brain regions and prion strains with different cell tropism.
    Neurobiol Dis. 2020;137:104783.
    PubMed     Abstract available


  79. RHEA EM, Raber J, Banks WA
    ApoE and cerebral insulin: Trafficking, receptors, and resistance.
    Neurobiol Dis. 2020;137:104755.
    PubMed     Abstract available


    March 2020
  80. BUTTERFIELD DA, Johnson LA
    APOE in Alzheimer's disease and neurodegeneration.
    Neurobiol Dis. 2020 Mar 21:104847. doi: 10.1016/j.nbd.2020.104847.
    PubMed    


  81. LIN AL, Parikh I, Yanckello LM, White RS, et al
    APOE genotype-dependent pharmacogenetic responses to rapamycin for preventing Alzheimer's disease.
    Neurobiol Dis. 2020;139:104834.
    PubMed     Abstract available


  82. SINGH PK, Chen ZL, Ghosh D, Strickland S, et al
    Increased plasma bradykinin level is associated with cognitive impairment in Alzheimer's patients.
    Neurobiol Dis. 2020 Mar 12:104833. doi: 10.1016/j.nbd.2020.104833.
    PubMed     Abstract available


  83. FLOWERS SA, Rebeck GW
    APOE in the normal brain.
    Neurobiol Dis. 2020;136:104724.
    PubMed     Abstract available


    February 2020
  84. LEWANDOWSKI CT, Weng JM, LaDu MJ
    Alzheimer's disease pathology in ApoE transgenic mouse models: The Who, What, When, Where, Why, and How.
    Neurobiol Dis. 2020 Feb 19:104811. doi: 10.1016/j.nbd.2020.104811.
    PubMed     Abstract available


  85. BUTTERFIELD DA, Mattson MP
    Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
    Neurobiol Dis. 2020 Feb 6:104795. doi: 10.1016/j.nbd.2020.104795.
    PubMed     Abstract available


  86. RAMAN S, Brookhouser N, Brafman DA
    Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk.
    Neurobiol Dis. 2020 Feb 4:104788. doi: 10.1016/j.nbd.2020.104788.
    PubMed     Abstract available


  87. SULLIVAN PM
    Influence of Western diet and APOE genotype on Alzheimer's disease risk.
    Neurobiol Dis. 2020 Feb 4:104790. doi: 10.1016/j.nbd.2020.104790.
    PubMed    


  88. BITTAR A, Bhatt N, Kayed R
    Advances and considerations in AD tau-targeted immunotherapy.
    Neurobiol Dis. 2020;134:104707.
    PubMed     Abstract available


  89. AFGHAH Z, Chen X, Geiger JD
    Role of endolysosomes and inter-organellar signaling in brain disease.
    Neurobiol Dis. 2020;134:104670.
    PubMed     Abstract available


  90. SOLTI K, Kuan WL, Forizs B, Kustos G, et al
    DJ-1 can form beta-sheet structured aggregates that co-localize with pathological amyloid deposits.
    Neurobiol Dis. 2020;134:104629.
    PubMed     Abstract available


  91. WEI Z, Meng X, El Fatimy R, Sun B, et al
    Environmental enrichment prevents Abeta oligomer-induced synaptic dysfunction through mirna-132 and hdac3 signaling pathways.
    Neurobiol Dis. 2020;134:104617.
    PubMed     Abstract available


  92. HOGLUND K, Schussler N, Kvartsberg H, Smailovic U, et al
    Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration.
    Neurobiol Dis. 2020;134:104645.
    PubMed     Abstract available


    January 2020
  93. TRAMUTOLA A, Lanzillotta C, Di Domenico F, Head E, et al
    Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome.
    Neurobiol Dis. 2020 Jan 24:104772. doi: 10.1016/j.nbd.2020.104772.
    PubMed     Abstract available


  94. SCHWAB AD, Thurston MJ, Machhi J, Olson KE, et al
    Immunotherapy for Parkinson's disease.
    Neurobiol Dis. 2020;137:104760.
    PubMed     Abstract available


  95. LAZIC D, Tesic V, Jovanovic M, Brkic M, et al
    Every-other-day feeding exacerbates inflammation and neuronal deficits in 5XFAD mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Jan 10:104745. doi: 10.1016/j.nbd.2020.104745.
    PubMed     Abstract available


  96. IMAMURA T, Yanagihara YT, Ohyagi Y, Nakamura N, et al
    Insulin deficiency promotes formation of toxic amyloid-beta42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
    Neurobiol Dis. 2020 Jan 9:104739. doi: 10.1016/j.nbd.2020.104739.
    PubMed     Abstract available


    October 2019
  97. ROYEA J, Martinot P, Hamel E
    Memory and cerebrovascular deficits recovered following angiotensin IV intervention in a mouse model of Alzheimer's disease.
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    September 2019
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    August 2019
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    July 2019
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    May 2019
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    April 2019
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    Gallic acid disruption of Abeta1-42 aggregation rescues cognitive decline of APP/PS1 double transgenic mouse.
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    Deceleration of the neurodegenerative phenotype in pyroglutamate-Abeta accumulating transgenic mice by oral treatment with the Abeta oligomer eliminating compound RD2.
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    February 2019
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