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  Alzheimer's Disease

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Articles published in Neurobiol Dis

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Single Articles


    March 2024
  1. TATO-FERNANDEZ C, Ekblad LL, Pietila E, Saunavaara V, et al
    Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET.
    Neurobiol Dis. 2024;192:106439.
    PubMed     Abstract available


  2. LONG DM, Cravetchi O, Chow ES, Allen C, et al
    The amyloid precursor protein intracellular domain induces sleep disruptions and its nuclear localization fluctuates in circadian pacemaker neurons in Drosophila and mice.
    Neurobiol Dis. 2024;192:106429.
    PubMed     Abstract available


    February 2024
  3. KATSUMATA Y, Wu X, Aung KZ, Gauthreaux K, et al
    Pathologic correlates of aging-related tau astrogliopathy: ARTAG is associated with LATE-NC and cerebrovascular pathologies, but not with ADNC.
    Neurobiol Dis. 2024;191:106412.
    PubMed     Abstract available


    January 2024
  4. KOURTI M, Metaxas A
    A systematic review and meta-analysis of tau phosphorylation in mouse models of familial Alzheimer's disease.
    Neurobiol Dis. 2024 Jan 31:106427. doi: 10.1016/j.nbd.2024.106427.
    PubMed     Abstract available


  5. IVANOVA M, Belaya I, Kucharikova N, de Sousa Maciel I, et al
    Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model.
    Neurobiol Dis. 2024;191:106410.
    PubMed     Abstract available


  6. GHARPURE M, Vyavahare S, Ahluwalia P, Gupta SK, et al
    Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology.
    Neurobiol Dis. 2024;191:106404.
    PubMed     Abstract available


  7. PIETILA E, Snellman A, Tuisku J, Helin S, et al
    Midlife insulin resistance, APOE genotype, and change in late-life brain beta-amyloid accumulation - A 5-year follow-up [(11)C]PIB-PET study.
    Neurobiol Dis. 2024;190:106385.
    PubMed     Abstract available


    December 2023
  8. ZHANG T, Dolga AM, Eisel ULM, Schmidt M, et al
    Novel crosstalk mechanisms between GluA3 and Epac2 in synaptic plasticity and memory in Alzheimer's disease.
    Neurobiol Dis. 2023 Dec 22:106389. doi: 10.1016/j.nbd.2023.106389.
    PubMed     Abstract available


  9. KOPCANOVA M, Tait L, Donoghue T, Stothart G, et al
    Resting-state EEG signatures of Alzheimer's disease are driven by periodic but not aperiodic changes.
    Neurobiol Dis. 2023 Dec 17:106380. doi: 10.1016/j.nbd.2023.106380.
    PubMed     Abstract available


  10. LIANG K, Li X, Guo Q, Ma J, et al
    Structural changes in the retina and serum HMGB1 levels are associated with decreased cognitive function in patients with Parkinson's disease.
    Neurobiol Dis. 2023;190:106379.
    PubMed     Abstract available


  11. HANERT A, Schonfeld R, Weber FD, Nowak A, et al
    Reduced overnight memory consolidation and associated alterations in sleep spindles and slow oscillations in early Alzheimer's disease.
    Neurobiol Dis. 2023 Dec 14:106378. doi: 10.1016/j.nbd.2023.106378.
    PubMed     Abstract available


  12. TIMSINA J, Ali M, Do A, Wang L, et al
    Harmonization of CSF and imaging biomarkers in Alzheimer's disease: Need and practical applications for genetics studies and preclinical classification.
    Neurobiol Dis. 2023;190:106373.
    PubMed     Abstract available


    November 2023
  13. NAJAR J, Thorvaldsson V, Kern S, Skoog J, et al
    Polygenic risk scores for Alzheimer's disease in relation to cognitive change: A representative sample from the general population followed over 16 years.
    Neurobiol Dis. 2023;189:106357.
    PubMed     Abstract available


  14. WOJDALA AL, Bellomo G, Gaetani L, Toja A, et al
    Trajectories of CSF and plasma biomarkers across Alzheimer's disease continuum: disease staging by NF-L, p-tau181, and GFAP.
    Neurobiol Dis. 2023;189:106356.
    PubMed     Abstract available


  15. LI K, Luo X, Zeng Q, Liu X, et al
    Gray matter structural covariance networks patterns associated with autopsy-confirmed LATE-NC compared to Alzheimer's disease pathology.
    Neurobiol Dis. 2023;189:106354.
    PubMed     Abstract available


    October 2023
  16. GAUTIER MK, Kelley CM, Lee SH, Alldred MJ, et al
    Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of down syndrome and Alzheimer's disease.
    Neurobiol Dis. 2023 Oct 25:106332. doi: 10.1016/j.nbd.2023.106332.
    PubMed     Abstract available


  17. HIGGINBOTHAM L, Carter EK, Dammer EB, Haque RU, et al
    Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
    Neurobiol Dis. 2023;186:106286.
    PubMed     Abstract available


    September 2023
  18. BOTELLO-MARABOTTO M, Martinez-Bisbal MC, Calero M, Bernardos A, et al
    Non-invasive biomarkers for mild cognitive impairment and Alzheimer's disease.
    Neurobiol Dis. 2023 Sep 26:106312. doi: 10.1016/j.nbd.2023.106312.
    PubMed     Abstract available


  19. CAO E, Ma D, Nayak S, Duong TQ, et al
    Deep learning combining FDG-PET and neurocognitive data accurately predicts MCI conversion to Alzheimer's dementia 3-year post MCI diagnosis.
    Neurobiol Dis. 2023 Sep 26:106310. doi: 10.1016/j.nbd.2023.106310.
    PubMed     Abstract available


  20. ISRAEL LL, Braubach O, Shatalova ES, Chepurna O, et al
    Exposure to environmental airborne particulate matter caused wide-ranged transcriptional changes and accelerated Alzheimer's-related pathology: A mouse study.
    Neurobiol Dis. 2023;187:106307.
    PubMed     Abstract available


  21. MEDINA-VERA D, Zambrana-Infantes EN, Lopez-Gambero AJ, Verheul-Campos J, et al
    Transcending the amyloid-beta dominance paradigm in Alzheimer's disease: An exploration of behavioural, metabolic, and gut microbiota phenotypes in 5xFAD mice.
    Neurobiol Dis. 2023 Sep 15:106295. doi: 10.1016/j.nbd.2023.106295.
    PubMed     Abstract available


  22. LISGARAS CP, Scharfman HE
    Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by medial septum.
    Neurobiol Dis. 2023 Sep 13:106294. doi: 10.1016/j.nbd.2023.106294.
    PubMed     Abstract available


  23. LEITAO ADG, Ahammad RU, Spencer B, Wu C, et al
    Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce alpha-synuclein in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2023;186:106285.
    PubMed     Abstract available


  24. SIGNAL B, Perez Suarez TG, Taberlay PC, Woodhouse A, et al
    Cellular specificity is key to deciphering epigenetic changes underlying Alzheimer's disease.
    Neurobiol Dis. 2023;186:106284.
    PubMed     Abstract available


  25. MEEHAN CE, Schantell M, Springer SD, Wiesman AI, et al
    Movement-related beta and gamma oscillations indicate parallels and disparities between Alzheimer's disease and HIV-associated neurocognitive disorder.
    Neurobiol Dis. 2023;186:106283.
    PubMed     Abstract available


    August 2023
  26. GIUFFRE GM, Quaranta D, Costantini EM, Citro S, et al
    Cerebrospinal fluid neurofilament light chain and total-tau as biomarkers of neurodegeneration in Alzheimer's disease and frontotemporal dementia.
    Neurobiol Dis. 2023 Aug 29:106267. doi: 10.1016/j.nbd.2023.106267.
    PubMed     Abstract available


  27. DAS M, Mao W, Voskobiynyk Y, Necula D, et al
    Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.
    Neurobiol Dis. 2023 Aug 15:106263. doi: 10.1016/j.nbd.2023.106263.
    PubMed     Abstract available


  28. ARMSTRONG MJ, Jin Y, Vattathil SM, Huang Y, et al
    Role of TET1-mediated epigenetic modulation in Alzheimer's disease.
    Neurobiol Dis. 2023;185:106257.
    PubMed     Abstract available


  29. EMMERSON JT, Do Carmo S, Liu Y, Shalhoub A, et al
    Progressive human-like tauopathy with downstream neurodegeneration and neurovascular compromise in a transgenic rat model.
    Neurobiol Dis. 2023;184:106227.
    PubMed     Abstract available


  30. DUMONT M, Agostinis A, Singh K, Swan E, et al
    Sex representation in neurodegenerative and psychiatric disorders' preclinical and clinical studies.
    Neurobiol Dis. 2023;184:106214.
    PubMed     Abstract available


    July 2023
  31. TROJAN E, Curzytek K, Cieslik P, Wieronska JM, et al
    Prenatal stress aggravates age-dependent cognitive decline, insulin signaling dysfunction, and the pro-inflammatory response in the APP(NL-F/NL-F) mouse model of Alzheimer's disease.
    Neurobiol Dis. 2023 Jul 6:106219. doi: 10.1016/j.nbd.2023.106219.
    PubMed     Abstract available


  32. LEGAZ A, Prado P, Moguilner S, Baez S, et al
    Social and non-social working memory in neurodegeneration.
    Neurobiol Dis. 2023;183:106171.
    PubMed     Abstract available


    June 2023
  33. MOWRY FE, Espejo-Porras F, Shijie J, Quadri Z, et al
    Chronic nSMase inhibition suppresses neuronal exosome spreading and sex-specifically attenuates amyloid pathology in APP knock-in Alzheimer's disease mice.
    Neurobiol Dis. 2023 Jun 24:106213. doi: 10.1016/j.nbd.2023.106213.
    PubMed     Abstract available


  34. SUN Y, Bae YE, Zhu J, Zhang Z, et al
    A splicing transcriptome-wide association study identifies novel altered splicing for Alzheimer's disease susceptibility.
    Neurobiol Dis. 2023 Jun 22:106209. doi: 10.1016/j.nbd.2023.106209.
    PubMed     Abstract available


  35. DI MAIO A, Nuzzo T, Gilio L, Serra M, et al
    Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients.
    Neurobiol Dis. 2023 Jun 17:106203. doi: 10.1016/j.nbd.2023.106203.
    PubMed     Abstract available


  36. BRADY ES, Griffiths J, Andrianova L, Bielska MH, et al
    Alterations to parvalbumin-expressing interneuron function and associated network oscillations in the hippocampal - medial prefrontal cortex circuit during natural sleep in App(NL-G-F/NL-G-F) mice.
    Neurobiol Dis. 2023;182:106151.
    PubMed     Abstract available


  37. FRANKLIN ZJ, Croce L, Dekeryte R, Delibegovic M, et al
    BACE cleavage of APP does not drive the diabetic phenotype of PLB4 mice.
    Neurobiol Dis. 2023;182:106142.
    PubMed     Abstract available


  38. ZOREC R, Vardjan N
    Adrenergic regulation of astroglial aerobic glycolysis and lipid metabolism: Towards a noradrenergic hypothesis of neurodegeneration.
    Neurobiol Dis. 2023;182:106132.
    PubMed     Abstract available


  39. LUTSHUMBA J, Wilcock D, Monson NL, Stowe AM, et al
    Sex-based differences in effector cells of the adaptive immune system during Alzheimer's disease and related dementias.
    Neurobiol Dis. 2023 Jun 15:106202. doi: 10.1016/j.nbd.2023.106202.
    PubMed     Abstract available


  40. PATEL PJ, Ren Y, Yan Z
    Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization.
    Neurobiol Dis. 2023 Jun 9:106192. doi: 10.1016/j.nbd.2023.106192.
    PubMed     Abstract available


  41. FOMINYKH V, Shadrin AA, Jaholkowski PP, Bahrami S, et al
    Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system.
    Neurobiol Dis. 2023 Jun 5:106174. doi: 10.1016/j.nbd.2023.106174.
    PubMed     Abstract available


  42. DE FLORES R, Demeilliez-Servouin S, Kuhn E, Chauveau L, et al
    Respective influence of beta-amyloid and APOE epsilon4 genotype on medial temporal lobe subregions in cognitively unimpaired older adults.
    Neurobiol Dis. 2023;181:106127.
    PubMed     Abstract available


  43. DUWAT C, Leal P, Vautheny A, Auregan G, et al
    Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology.
    Neurobiol Dis. 2023;181:106116.
    PubMed     Abstract available


  44. PEDERSEN TJ, Keil SA, Han W, Wang MX, et al
    The effect of aquaporin-4 mis-localization on Abeta deposition in mice.
    Neurobiol Dis. 2023;181:106100.
    PubMed     Abstract available


    May 2023
  45. SNELLMAN A, Ekblad LL, Ashton NJ, Karikari TK, et al
    Head-to-head comparison of plasma p-tau181, p-tau231 and glial fibrillary acidic protein in clinically unimpaired elderly with three levels of APOE4-related risk for Alzheimer's disease.
    Neurobiol Dis. 2023 May 31:106175. doi: 10.1016/j.nbd.2023.106175.
    PubMed     Abstract available


  46. MUSAEUS CS, Frederiksen KS, Andersen BB, Hogh P, et al
    Detection of subclinical epileptiform discharges in Alzheimer's disease using long-term outpatient EEG monitoring.
    Neurobiol Dis. 2023 May 15:106149. doi: 10.1016/j.nbd.2023.106149.
    PubMed     Abstract available


  47. MABROUK R, Miettinen PO, Tanila H
    Most dystrophic neurites in the common 5xFAD Alzheimer mouse model originate from axon terminals.
    Neurobiol Dis. 2023;182:106150.
    PubMed     Abstract available


  48. CHEN Z, Reynolds RH, Pardinas AF, Gagliano Taliun SA, et al
    The contribution of Neanderthal introgression and natural selection to neurodegenerative diseases.
    Neurobiol Dis. 2023;180:106082.
    PubMed     Abstract available


  49. VARBANOV H, Jia S, Kochlamazashvili G, Bhattacharya S, et al
    Rescue of synaptic and cognitive functions in polysialic acid-deficient mice and dementia models by short polysialic acid fragments.
    Neurobiol Dis. 2023;180:106079.
    PubMed     Abstract available


    April 2023
  50. WITTRAHM R, Takalo M, Kuulasmaa T, Makinen PM, et al
    Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPbeta levels in cerebrospinal fluid and 2D/3D cell culture models.
    Neurobiol Dis. 2023;182:106140.
    PubMed     Abstract available


  51. SHIN YJ, Evitts KM, Jin S, Howard C, et al
    Amyloid beta peptides (Abeta) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model.
    Neurobiol Dis. 2023 Apr 14:106125. doi: 10.1016/j.nbd.2023.106125.
    PubMed     Abstract available


  52. LI T, Li D, Wei Q, Shi M, et al
    Dissecting the neurovascular unit in physiology and Alzheimer's disease: Functions, imaging tools and genetic mouse models.
    Neurobiol Dis. 2023 Apr 4:106114. doi: 10.1016/j.nbd.2023.106114.
    PubMed     Abstract available


  53. GRECO GA, Rock M, Amontree M, Lanfranco MF, et al
    CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice.
    Neurobiol Dis. 2023;179:106057.
    PubMed     Abstract available


  54. PRADO P, Moguilner S, Mejia JA, Sainz-Ballesteros A, et al
    Source space connectomics of neurodegeneration: One-metric approach does not fit all.
    Neurobiol Dis. 2023;179:106047.
    PubMed     Abstract available


  55. AFROZ T, Chevalier E, Audrain M, Dumayne C, et al
    Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
    Neurobiol Dis. 2023;179:106050.
    PubMed     Abstract available


    March 2023
  56. RIZZELLO E, Pimpinella D, Pignataro A, Titta G, et al
    Lamotrigine rescues neuronal alterations and prevents seizure-induced memory decline in an Alzheimer's disease mouse model.
    Neurobiol Dis. 2023 Mar 29:106106. doi: 10.1016/j.nbd.2023.106106.
    PubMed     Abstract available


  57. TEIPEL S, Grothe MJ
    MRI-based basal forebrain atrophy and volumetric signatures associated with limbic TDP-43 compared to Alzheimer's disease pathology.
    Neurobiol Dis. 2023;180:106070.
    PubMed     Abstract available


  58. PARKA A, Degel C, Dreyer J, Richter U, et al
    Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model.
    Neurobiol Dis. 2023;178:106012.
    PubMed     Abstract available


  59. CORSI GI, Gadekar VP, Haukedal H, Doncheva NT, et al
    The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression.
    Neurobiol Dis. 2023;178:105980.
    PubMed     Abstract available


    February 2023
  60. TOHUMEKEN S, Deme P, Yoo SW, Gupta S, et al
    Neuronal deletion of nSMase2 reduces the production of Abeta and directly protects neurons.
    Neurobiol Dis. 2023;177:105987.
    PubMed     Abstract available


  61. BAH TM, Siler DA, Ibrahim AH, Cetas JS, et al
    Fluid dynamics in aging-related dementias.
    Neurobiol Dis. 2023;177:105986.
    PubMed     Abstract available


  62. REN P, Ding W, Li S, Liu G, et al
    Regional transcriptional vulnerability to basal forebrain functional dysconnectivity in mild cognitive impairment patients.
    Neurobiol Dis. 2023;177:105983.
    PubMed     Abstract available


    January 2023
  63. AINANI H, Bouchmaa N, Mrid RB, El Fatimy R, et al
    Liquid-liquid phase separation of protein tau: An emerging process in Alzheimer's disease pathogenesis.
    Neurobiol Dis. 2023 Jan 23:106011. doi: 10.1016/j.nbd.2023.106011.
    PubMed     Abstract available


  64. SAUNDERS T, Gunn C, Blennow K, Kvartsberg H, et al
    Neurogranin in Alzheimer's disease and ageing: A human post-mortem study.
    Neurobiol Dis. 2023 Jan 6:105991. doi: 10.1016/j.nbd.2023.105991.
    PubMed     Abstract available


  65. GOTZE K, Vrillon A, Bouaziz-Amar E, Mouton-Liger F, et al
    Plasma neurofilament light chain in memory clinic practice: Evidence from a real-life study.
    Neurobiol Dis. 2023;176:105937.
    PubMed     Abstract available


    December 2022
  66. GIRONDA SC, Day SM, Clarke CW, Snipes JA, et al
    Ethanol exposure alters Alzheimer's-related pathology, behavior, and metabolism in APP/PS1 mice.
    Neurobiol Dis. 2022 Dec 16:105967. doi: 10.1016/j.nbd.2022.105967.
    PubMed     Abstract available


  67. ZHANG H, Chen L, Johnston KG, Crapser J, et al
    Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease.
    Neurobiol Dis. 2022;176:105939.
    PubMed     Abstract available


  68. HERZOG R, Rosas FE, Whelan R, Fittipaldi S, et al
    Genuine high-order interactions in brain networks and neurodegeneration.
    Neurobiol Dis. 2022;175:105918.
    PubMed     Abstract available


  69. GALLWITZ L, Schmidt L, Marques ARA, Tholey A, et al
    Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease.
    Neurobiol Dis. 2022;175:105919.
    PubMed     Abstract available


  70. NG CAS, Biran LP, Galvano E, Mandelblatt J, et al
    Chemotherapy promotes astrocytic response to Abeta deposition, but not Abeta levels, in a mouse model of amyloid and APOE.
    Neurobiol Dis. 2022;175:105915.
    PubMed     Abstract available


    November 2022
  71. FELSKY D, Santa-Maria I, Cosacak MI, French L, et al
    The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms.
    Neurobiol Dis. 2022 Nov 30:105938. doi: 10.1016/j.nbd.2022.105938.
    PubMed     Abstract available


  72. SARKAR S
    Microglial ion channels: Key players in non-cell autonomous neurodegeneration.
    Neurobiol Dis. 2022;174:105861.
    PubMed     Abstract available


    October 2022
  73. LIN L, Petralia RS, Holtzclaw L, Wang YX, et al
    Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice.
    Neurobiol Dis. 2022 Oct 6:105887. doi: 10.1016/j.nbd.2022.105887.
    PubMed     Abstract available


  74. QUINN JF, Kelly MJ, Harris CJ, Hack W, et al
    The novel estrogen modulator STX attenuates Amyloid-beta neurotoxicity in the 5XFAD mouse model of Alzheimer's disease.
    Neurobiol Dis. 2022 Oct 6:105888. doi: 10.1016/j.nbd.2022.105888.
    PubMed     Abstract available


  75. JIN SX, Liu L, Li S, Meunier AL, et al
    Abeta oligomers from human brain impair mossy fiber LTP in CA3 of hippocampus, but activating cAMP-PKA and cGMP-PKG prevents this.
    Neurobiol Dis. 2022;172:105816.
    PubMed     Abstract available


    September 2022
  76. KATSUMATA Y, Shade LM, Hohman TJ, Schneider JA, et al
    Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.
    Neurobiol Dis. 2022 Sep 30:105880. doi: 10.1016/j.nbd.2022.105880.
    PubMed     Abstract available


  77. KHANDELWAL M, Manglani K, Upadhyay P, Azad M, et al
    AdipoRon induces AMPK activation and ameliorates Alzheimer's like pathologies and associated cognitive impairment in APP/PS1 mice.
    Neurobiol Dis. 2022;174:105876.
    PubMed     Abstract available


  78. DE FISENNE MA, Yilmaz Z, De Decker R, Suain V, et al
    Alzheimer PHF-tau aggregates do not spread tau pathology to the brain via the Retino-tectal projection after intraocular injection in mouse models.
    Neurobiol Dis. 2022 Sep 22:105875. doi: 10.1016/j.nbd.2022.105875.
    PubMed     Abstract available


  79. LI Y, Xia M, Meng S, Wu D, et al
    MicroRNA-29c-3p in dual-labeled exosome is a potential diagnostic marker of subjective cognitive decline.
    Neurobiol Dis. 2022;171:105800.
    PubMed     Abstract available


  80. YANG Z, Wang J, Chen J, Luo M, et al
    High-resolution NMR metabolomics of patients with subjective cognitive decline plus: Perturbations in the metabolism of glucose and branched-chain amino acids.
    Neurobiol Dis. 2022;171:105782.
    PubMed     Abstract available


  81. CESPEDES M, Jacobs KR, Maruff P, Rembach A, et al
    Systemic perturbations of the kynurenine pathway precede progression to dementia independently of amyloid-beta.
    Neurobiol Dis. 2022;171:105783.
    PubMed     Abstract available


  82. BLESSING EM, Parekh A, Betensky RA, Babb J, et al
    Association between lower body temperature and increased tau pathology in cognitively normal older adults.
    Neurobiol Dis. 2022;171:105748.
    PubMed     Abstract available


    August 2022
  83. GU Z, Cao H, Zuo C, Huang Y, et al
    TFEB in Alzheimer's disease: From molecular mechanisms to therapeutic implications.
    Neurobiol Dis. 2022 Aug 25:105855. doi: 10.1016/j.nbd.2022.105855.
    PubMed     Abstract available


  84. MEHTA NH, Suss RA, Dyke JP, Theise ND, et al
    Quantifying cerebrospinal fluid dynamics: A review of human neuroimaging contributions to CSF physiology and neurodegenerative disease.
    Neurobiol Dis. 2022;170:105776.
    PubMed     Abstract available


  85. WILLIAMS ET, Chen X, Otero PA, Moore DJ, et al
    Understanding the contributions of VPS35 and the retromer in neurodegenerative disease.
    Neurobiol Dis. 2022;170:105768.
    PubMed     Abstract available


    July 2022
  86. MARTINEZ-DRUDIS L, Sheta R, Pellegrinato R, Loukili S, et al
    Inhibition of PLK2 activity affects APP and tau pathology and improves synaptic content in a sex-dependent manner in a 3xTg mouse model of Alzheimer's disease.
    Neurobiol Dis. 2022;172:105833.
    PubMed     Abstract available


  87. ZHANG Y, Gao H, Zheng W, Xu H, et al
    Current understanding of the interactions between metal ions and Apolipoprotein E in Alzheimer's disease.
    Neurobiol Dis. 2022;172:105824.
    PubMed     Abstract available


  88. QIAO Y, Gast G, Su X, Saito T, et al
    Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing.
    Neurobiol Dis. 2022 Jul 14:105820. doi: 10.1016/j.nbd.2022.105820.
    PubMed     Abstract available


  89. NORAMBUENA A, Sun X, Wallrabe H, Cao R, et al
    SOD1 mediates lysosome-to-mitochondria communication and its dysregulation by amyloid-beta oligomers.
    Neurobiol Dis. 2022;169:105737.
    PubMed     Abstract available


    June 2022
  90. RAMAMOORTHY K, Yoshimura R, Al-Juburi S, Anandam KY, et al
    Alzheimer's disease is associated with disruption in thiamin transport physiology: A potential role for neuroinflammation.
    Neurobiol Dis. 2022 Jun 21:105799. doi: 10.1016/j.nbd.2022.105799.
    PubMed     Abstract available


  91. JOHNSON AC, Uhlig F, Einwag Z, Cataldo N, et al
    The neuroendocrine stress response impairs hippocampal vascular function and memory in male and female rats.
    Neurobiol Dis. 2022;168:105717.
    PubMed     Abstract available


  92. AMIN J, Erskine D, Donaghy PC, Surendranathan A, et al
    Inflammation in dementia with Lewy bodies.
    Neurobiol Dis. 2022;168:105698.
    PubMed     Abstract available


  93. KORF JM, Ganesh BP, McCullough LD
    Gut dysbiosis and age-related neurological diseases in females.
    Neurobiol Dis. 2022;168:105695.
    PubMed     Abstract available


  94. AHMED MM, Wang AC, Elos M, Chial HJ, et al
    The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice.
    Neurobiol Dis. 2022;168:105694.
    PubMed     Abstract available


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    The association of enlarged perivascular space with microglia-related inflammation and Alzheimer's pathology in cognitively normal elderly.
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    Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.
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    Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology.
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    Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage.
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    Altered protein expression of membrane transporters in isolated cerebral microvessels and brain cortex of a rat Alzheimer's disease model.
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    Soluble TREM2: Innocent bystander or active player in neurological diseases?
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    CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer's disease.
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    Human apolipoprotein E isoforms are differentially sialylated and the sialic acid moiety in ApoE2 attenuates ApoE2-Abeta interaction and Abeta fibrillation.
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    The role of Alzheimer's disease risk genes in endolysosomal pathways.
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    Quantitative detection of grey and white matter amyloid pathology using a combination of K114 and CRANAD-3 fluorescence.
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    Alternative platelet activation pathways and their role in neurodegenerative diseases.
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    Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer's disease and related tauopathies.
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    Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.
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    Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease.
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    Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease.
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    Impaired plasticity of intrinsic excitability in the dentate gyrus alters spike transfer in a mouse model of Alzheimer's disease.
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    Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5xFAD mice.
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    Epigenetic mechanisms underlying enhancer modulation of neuronal identity, neuronal activity and neurodegeneration.
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    Changes in the brain transcriptome after DNA Abeta42 trimer immunization in a 3xTg-AD mouse model.
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    December 2020
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    Leptin enhances adult neurogenesis and reduces pathological features in a transgenic mouse model of Alzheimer's disease.
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    November 2020
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    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
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    October 2020
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    A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology.
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    TDP-43 and tau oligomers in Alzheimer's disease, amyotrophic lateral sclerosis, and frontotemporal dementia.
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    June 2020
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    Cerebrospinal fluid ceruloplasmin levels predict cognitive decline and brain atrophy in people with underlying beta-amyloid pathology.
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    APOE-amyloid interaction: Therapeutic targets.
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    April 2020
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    Region-specific glial homeostatic signature in prion diseases is replaced by a uniform neuroinflammation signature, common for brain regions and prion strains with different cell tropism.
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    February 2020
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    Advances and considerations in AD tau-targeted immunotherapy.
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    Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration.
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