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Articles published in Neurobiol Dis

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    September 2021
  1. OCHIAI T, Sano T, Nagayama T, Kubota N, et al
    Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Sep 16:105510. doi: 10.1016/j.nbd.2021.105510.
    PubMed     Abstract available

    August 2021
  2. FITZ NF, Wang J, Kamboh MI, Koldamova R, et al
    Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease.
    Neurobiol Dis. 2021 Aug 16:105481. doi: 10.1016/j.nbd.2021.105481.
    PubMed     Abstract available

  3. WANG X, Zhou X, Uberseder B, Lee J, et al
    Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer's disease.
    Neurobiol Dis. 2021;158:105463.
    PubMed     Abstract available

    July 2021
  4. FUSILIER AR, Davis JA, Paul JR, Yates SD, et al
    Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Jul 29:105454. doi: 10.1016/j.nbd.2021.105454.
    PubMed     Abstract available

    June 2021
  5. PAPPOLLA MA, Perry G, Fang X, Zagorski M, et al
    Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease.
    Neurobiol Dis. 2021;156:105403.
    PubMed     Abstract available

    May 2021
  6. ZHANG L, Qin Z, Sharmin F, Lin W, et al
    Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 May 24:105402. doi: 10.1016/j.nbd.2021.105402.
    PubMed     Abstract available

    March 2021
  7. JIANG N, Cupolillo D, Grosjean N, Muller E, et al
    Impaired plasticity of intrinsic excitability in the dentate gyrus alters spike transfer in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Mar 22:105345. doi: 10.1016/j.nbd.2021.105345.
    PubMed     Abstract available

    February 2021
  8. TSAI AP, Lin PB, Dong C, Moutinho M, et al
    INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia.
    Neurobiol Dis. 2021 Feb 22:105303. doi: 10.1016/j.nbd.2021.105303.
    PubMed     Abstract available

  9. BASAK JM, Ferreiro A, Cohen LS, Sheehan PW, et al
    Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021;152:105292.
    PubMed     Abstract available

  10. XUE F, Tian J, Yu C, Du H, et al
    Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5xFAD mice.
    Neurobiol Dis. 2021 Feb 1:105272. doi: 10.1016/j.nbd.2021.105272.
    PubMed     Abstract available

    January 2021
  11. ALCANTARA-GONZALEZ D, Chartampila E, Criscuolo C, Scharfman HE, et al
    Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine.
    Neurobiol Dis. 2021 Jan 20:105274. doi: 10.1016/j.nbd.2021.105274.
    PubMed     Abstract available

    December 2020
  12. CALIO ML, Mosini AC, Marinho DS, Salles GN, et al
    Leptin enhances adult neurogenesis and reduces pathological features in a transgenic mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Dec 7:105219. doi: 10.1016/j.nbd.2020.105219.
    PubMed     Abstract available

  13. PIMENOVA AA, Herbinet M, Gupta I, Machlovi SI, et al
    Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response.
    Neurobiol Dis. 2020 Dec 7:105217. doi: 10.1016/j.nbd.2020.105217.
    PubMed     Abstract available

    November 2020
  14. ANDERSEN JV, Christensen SK, Westi EW, Diaz-delCastillo M, et al
    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Nov 23:105198. doi: 10.1016/j.nbd.2020.105198.
    PubMed     Abstract available

    October 2020
  15. PENTZ R, Iulita MF, Mikutra-Cencora M, Ducatenzeiler A, et al
    A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology.
    Neurobiol Dis. 2020 Oct 29:105150. doi: 10.1016/j.nbd.2020.105150.
    PubMed     Abstract available

  16. MONTALBANO M, McAllen S, Cascio FL, Sengupta U, et al
    TDP-43 and tau oligomers in Alzheimer's disease, amyotrophic lateral sclerosis, and frontotemporal dementia.
    Neurobiol Dis. 2020 Oct 13:105130. doi: 10.1016/j.nbd.2020.105130.
    PubMed     Abstract available

  17. STEPLER KE, Mahoney ER, Kofler J, Hohman TJ, et al
    Inclusion of African American/black adults in a pilot brain proteomics study of Alzheimer's disease.
    Neurobiol Dis. 2020 Oct 10:105129. doi: 10.1016/j.nbd.2020.105129.
    PubMed     Abstract available

    September 2020
  18. EVANS AK, Ardestani P, Yi B, Park HH, et al
    Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease.
    Neurobiol Dis. 2020 Sep 21:105089. doi: 10.1016/j.nbd.2020.105089.
    PubMed     Abstract available

  19. VON SAUCKEN VE, Jay TR, Landreth GE
    The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Sep 2:105072. doi: 10.1016/j.nbd.2020.105072.
    PubMed     Abstract available

    August 2020
  20. AGRAWAL RR, Montesinos J, Larrea D, Area-Gomez E, et al
    The silence of the fats: A mam's story about Alzheimer.
    Neurobiol Dis. 2020 Aug 28:105062. doi: 10.1016/j.nbd.2020.105062.
    PubMed     Abstract available

  21. MULLINS AE, Kam K, Parekh A, Bubu OM, et al
    Obstructive Sleep Apnea and Its Treatment in Aging: Effects on Alzheimer's disease Biomarkers, Cognition, Brain Structure and Neurophysiology.
    Neurobiol Dis. 2020 Aug 26:105054. doi: 10.1016/j.nbd.2020.105054.
    PubMed     Abstract available

  22. CHIASSEU M, Fesharaki A, Saito T, Saido TC, et al
    Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in.
    Neurobiol Dis. 2020 Aug 25:105059. doi: 10.1016/j.nbd.2020.105059.
    PubMed     Abstract available

  23. ZHANG X, Trebak F, Souza LAC, Shi J, et al
    Small RNA modifications in Alzheimer's disease.
    Neurobiol Dis. 2020 Aug 21:105058. doi: 10.1016/j.nbd.2020.105058.
    PubMed     Abstract available

    July 2020
  24. LUCEY BP
    It's complicated: The relationship between sleep and Alzheimer's disease in humans.
    Neurobiol Dis. 2020 Jul 29:105031. doi: 10.1016/j.nbd.2020.105031.
    PubMed     Abstract available

  25. GHALI MGZ, Marchenko V, Yasargil MG, Ghali GZ, et al
    Structure and function of the perivascular fluid compartment and vertebral venous plexus: Illumining a novel theory on mechanisms underlying the pathogenesis of Alzheimer's, cerebral small vessel, and neurodegenerative diseases.
    Neurobiol Dis. 2020 Jul 17:105022. doi: 10.1016/j.nbd.2020.105022.
    PubMed     Abstract available

  26. PLOTKIN SS, Cashman NR
    Passive immunotherapies targeting Abeta and tau in Alzheimer's disease.
    Neurobiol Dis. 2020 Jul 16:105010. doi: 10.1016/j.nbd.2020.105010.
    PubMed     Abstract available

  27. LAU DHW, Paillusson S, Hartopp N, Rupawala H, et al
    Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain.
    Neurobiol Dis. 2020 Jul 16:105020. doi: 10.1016/j.nbd.2020.105020.
    PubMed     Abstract available

    June 2020
  28. NEUNER SM, Tcw J, Goate AM
    Genetic architecture of Alzheimer's disease.
    Neurobiol Dis. 2020 Jun 18:104976. doi: 10.1016/j.nbd.2020.104976.
    PubMed     Abstract available

  29. SCHWABE T, Srinivasan K, Rhinn H
    Shifting paradigms: The central role of microglia in Alzheimer's disease.
    Neurobiol Dis. 2020 Jun 11:104962. doi: 10.1016/j.nbd.2020.104962.
    PubMed     Abstract available

  30. SCHULTZ SA, Strain JF, Adedokun A, Wang Q, et al
    Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease.
    Neurobiol Dis. 2020;142:104960.
    PubMed     Abstract available

  31. PETRUSHINA I, Hovakimyan A, Harahap-Carrillo IS, Davtyan H, et al
    Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials.
    Neurobiol Dis. 2020;139:104823.
    PubMed     Abstract available

  32. DIOUF I, Bush AI, Ayton S
    Cerebrospinal fluid ceruloplasmin levels predict cognitive decline and brain atrophy in people with underlying beta-amyloid pathology.
    Neurobiol Dis. 2020;139:104810.
    PubMed     Abstract available

  33. HSU S, Pimenova AA, Hayes K, Villa JA, et al
    Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2.
    Neurobiol Dis. 2020;139:104817.
    PubMed     Abstract available

  34. BORRECA A, Valeri F, De Luca M, Ernst L, et al
    Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Abeta pathology.
    Neurobiol Dis. 2020;139:104787.
    PubMed     Abstract available

    May 2020
  35. GUERREIRO R, Gibbons E, Tabuas-Pereira M, Kun-Rodrigues C, et al
    Genetic architecture of common non-Alzheimer's disease dementias.
    Neurobiol Dis. 2020 May 18:104946. doi: 10.1016/j.nbd.2020.104946.
    PubMed     Abstract available

  36. PETERS C, Bascunan D, Burgos CF, Bobadilla C, et al
    Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease.
    Neurobiol Dis. 2020 May 17:104938. doi: 10.1016/j.nbd.2020.104938.
    PubMed     Abstract available

  37. PIMENOVA AA, Goate AM
    Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations.
    Neurobiol Dis. 2020;138:104785.
    PubMed     Abstract available

  38. WISNIEWSKI T, Drummond E
    APOE-amyloid interaction: Therapeutic targets.
    Neurobiol Dis. 2020;138:104784.
    PubMed     Abstract available

    April 2020
  39. MAKARAVA N, Chang JC, Molesworth K, Baskakov IV, et al
    Region-specific glial homeostatic signature in prion diseases is replaced by a uniform neuroinflammation signature, common for brain regions and prion strains with different cell tropism.
    Neurobiol Dis. 2020;137:104783.
    PubMed     Abstract available

  40. RHEA EM, Raber J, Banks WA
    ApoE and cerebral insulin: Trafficking, receptors, and resistance.
    Neurobiol Dis. 2020;137:104755.
    PubMed     Abstract available

    March 2020
  41. BUTTERFIELD DA, Johnson LA
    APOE in Alzheimer's disease and neurodegeneration.
    Neurobiol Dis. 2020 Mar 21:104847. doi: 10.1016/j.nbd.2020.104847.

  42. LIN AL, Parikh I, Yanckello LM, White RS, et al
    APOE genotype-dependent pharmacogenetic responses to rapamycin for preventing Alzheimer's disease.
    Neurobiol Dis. 2020;139:104834.
    PubMed     Abstract available

  43. SINGH PK, Chen ZL, Ghosh D, Strickland S, et al
    Increased plasma bradykinin level is associated with cognitive impairment in Alzheimer's patients.
    Neurobiol Dis. 2020 Mar 12:104833. doi: 10.1016/j.nbd.2020.104833.
    PubMed     Abstract available

  44. FLOWERS SA, Rebeck GW
    APOE in the normal brain.
    Neurobiol Dis. 2020;136:104724.
    PubMed     Abstract available

    February 2020
    Alzheimer's disease pathology in ApoE transgenic mouse models: The Who, What, When, Where, Why, and How.
    Neurobiol Dis. 2020 Feb 19:104811. doi: 10.1016/j.nbd.2020.104811.
    PubMed     Abstract available

  46. BUTTERFIELD DA, Mattson MP
    Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
    Neurobiol Dis. 2020 Feb 6:104795. doi: 10.1016/j.nbd.2020.104795.
    PubMed     Abstract available

  47. RAMAN S, Brookhouser N, Brafman DA
    Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk.
    Neurobiol Dis. 2020 Feb 4:104788. doi: 10.1016/j.nbd.2020.104788.
    PubMed     Abstract available

    Influence of Western diet and APOE genotype on Alzheimer's disease risk.
    Neurobiol Dis. 2020 Feb 4:104790. doi: 10.1016/j.nbd.2020.104790.

  49. BITTAR A, Bhatt N, Kayed R
    Advances and considerations in AD tau-targeted immunotherapy.
    Neurobiol Dis. 2020;134:104707.
    PubMed     Abstract available

  50. AFGHAH Z, Chen X, Geiger JD
    Role of endolysosomes and inter-organellar signaling in brain disease.
    Neurobiol Dis. 2020;134:104670.
    PubMed     Abstract available

  51. SOLTI K, Kuan WL, Forizs B, Kustos G, et al
    DJ-1 can form beta-sheet structured aggregates that co-localize with pathological amyloid deposits.
    Neurobiol Dis. 2020;134:104629.
    PubMed     Abstract available

  52. WEI Z, Meng X, El Fatimy R, Sun B, et al
    Environmental enrichment prevents Abeta oligomer-induced synaptic dysfunction through mirna-132 and hdac3 signaling pathways.
    Neurobiol Dis. 2020;134:104617.
    PubMed     Abstract available

  53. HOGLUND K, Schussler N, Kvartsberg H, Smailovic U, et al
    Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration.
    Neurobiol Dis. 2020;134:104645.
    PubMed     Abstract available

    January 2020
  54. TRAMUTOLA A, Lanzillotta C, Di Domenico F, Head E, et al
    Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome.
    Neurobiol Dis. 2020 Jan 24:104772. doi: 10.1016/j.nbd.2020.104772.
    PubMed     Abstract available

  55. SCHWAB AD, Thurston MJ, Machhi J, Olson KE, et al
    Immunotherapy for Parkinson's disease.
    Neurobiol Dis. 2020;137:104760.
    PubMed     Abstract available

  56. LAZIC D, Tesic V, Jovanovic M, Brkic M, et al
    Every-other-day feeding exacerbates inflammation and neuronal deficits in 5XFAD mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Jan 10:104745. doi: 10.1016/j.nbd.2020.104745.
    PubMed     Abstract available

  57. IMAMURA T, Yanagihara YT, Ohyagi Y, Nakamura N, et al
    Insulin deficiency promotes formation of toxic amyloid-beta42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
    Neurobiol Dis. 2020 Jan 9:104739. doi: 10.1016/j.nbd.2020.104739.
    PubMed     Abstract available

    October 2019
  58. ROYEA J, Martinot P, Hamel E
    Memory and cerebrovascular deficits recovered following angiotensin IV intervention in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2019;134:104644.
    PubMed     Abstract available

    September 2019
  59. CALEB AA, Akiyama T, Kimura A, Kimura Y, et al
    Network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with Abeta in a mice model of early-stage Alzheimer's disease.
    Neurobiol Dis. 2019 Sep 5:104603. doi: 10.1016/j.nbd.2019.104603.
    PubMed     Abstract available

  60. DEMIREV AV, Song HL, Cho MH, Cho K, et al
    V232M substitution restricts a distinct O-glycosylation of PLD3 and its neuroprotective function.
    Neurobiol Dis. 2019;129:182-194.
    PubMed     Abstract available

    August 2019
  61. SINGH-BAINS MK, Linke V, Austria MDR, Tan AYS, et al
    Altered microglia and neurovasculature in the Alzheimer's disease cerebellum.
    Neurobiol Dis. 2019 Aug 24:104589. doi: 10.1016/j.nbd.2019.104589.
    PubMed     Abstract available

  62. GONCALVES FQ, Lopes JP, Silva HB, Lemos C, et al
    Synaptic and memory dysfunction in a beta-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine.
    Neurobiol Dis. 2019 Aug 5:104570. doi: 10.1016/j.nbd.2019.104570.
    PubMed     Abstract available

  63. PEDRAZZOLI M, Losurdo M, Paolone G, Medelin M, et al
    Glucocorticoid receptors modulate dendritic spine plasticity and microglia activity in an animal model of Alzheimer's disease.
    Neurobiol Dis. 2019 Aug 5:104568. doi: 10.1016/j.nbd.2019.104568.
    PubMed     Abstract available

  64. GARCIA-RILL E, Mahaffey S, Hyde JR, Urbano FJ, et al
    Bottom-up gamma maintenance in various disorders.
    Neurobiol Dis. 2019;128:31-39.
    PubMed     Abstract available

    July 2019
  65. KIM B, Elzinga SE, Henn RE, McGinley LM, et al
    The effects of insulin and insulin-like growth factor I on amyloid precursor protein phosphorylation in in vitro and in vivo models of Alzheimer's disease.
    Neurobiol Dis. 2019 Jul 23:104541. doi: 10.1016/j.nbd.2019.104541.
    PubMed     Abstract available

  66. LECCA D, Bader M, Tweedie D, Hoffman AF, et al
    (-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice.
    Neurobiol Dis. 2019 Jul 8:104528. doi: 10.1016/j.nbd.2019.104528.
    PubMed     Abstract available

  67. DELBOVE CE, Strothman CE, Lazarenko RM, Huang H, et al
    Reciprocal modulation between amyloid precursor protein and synaptic membrane cholesterol revealed by live cell imaging.
    Neurobiol Dis. 2019;127:449-461.
    PubMed     Abstract available

  68. DETREZ JR, Maurin H, Van Kolen K, Willems R, et al
    Regional vulnerability and spreading of hyperphosphorylated tau in seeded mouse brain.
    Neurobiol Dis. 2019;127:398-409.
    PubMed     Abstract available

    June 2019
  69. BALU DT, Pantazopoulos H, Huang CCY, Muszynski K, et al
    Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease.
    Neurobiol Dis. 2019 Jun 15:104511. doi: 10.1016/j.nbd.2019.104511.
    PubMed     Abstract available

  70. MENDONCA CF, Kuras M, Nogueira FCS, Pla I, et al
    Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer's disease.
    Neurobiol Dis. 2019 Jun 14:104509. doi: 10.1016/j.nbd.2019.104509.
    PubMed     Abstract available

  71. BUHL E, Higham JP, Hodge JJL
    Alzheimer's disease-associated tau alters Drosophila circadian activity, sleep and clock neuron electrophysiology.
    Neurobiol Dis. 2019 Jun 14:104507. doi: 10.1016/j.nbd.2019.104507.
    PubMed     Abstract available

  72. ESSAYAN-PEREZ S, Zhou B, Nabet AM, Wernig M, et al
    Modeling Alzheimer's disease with human iPS cells: advancements, lessons, and applications.
    Neurobiol Dis. 2019 Jun 13:104503. doi: 10.1016/j.nbd.2019.104503.
    PubMed     Abstract available

    May 2019
  73. DAVILA-BOUZIGUET E, Targa-Fabra G, Avila J, Soriano E, et al
    Differential accumulation of Tau phosphorylated at residues Thr231, Ser262 and Thr205 in hippocampal interneurons and its modulation by Tau mutations (VLW) and amyloid-beta peptide.
    Neurobiol Dis. 2019;125:232-244.
    PubMed     Abstract available

    April 2019
  74. VARELA EV, Etter G, Williams S
    Excitatory-inhibitory imbalance in Alzheimer's disease and therapeutic significance.
    Neurobiol Dis. 2019 Apr 15. pii: S0969-9961(18)30759.
    PubMed     Abstract available

  75. TETER B, Morihara T, Lim GP, Chu T, et al
    Curcumin restores innate immune Alzheimer's disease risk gene expression to ameliorate Alzheimer pathogenesis.
    Neurobiol Dis. 2019 Apr 2. pii: S0969-9961(19)30045.
    PubMed     Abstract available

  76. DIOUF I, Fazlollahi A, Bush AI, Ayton S, et al
    Cerebrospinal fluid ferritin levels predict brain hypometabolism in people with underlying beta-amyloid pathology.
    Neurobiol Dis. 2019;124:335-339.
    PubMed     Abstract available

  77. YU M, Chen X, Liu J, Ma Q, et al
    Gallic acid disruption of Abeta1-42 aggregation rescues cognitive decline of APP/PS1 double transgenic mouse.
    Neurobiol Dis. 2019;124:67-80.
    PubMed     Abstract available

  78. SCHEMMERT S, Schartmann E, Honold D, Zafiu C, et al
    Deceleration of the neurodegenerative phenotype in pyroglutamate-Abeta accumulating transgenic mice by oral treatment with the Abeta oligomer eliminating compound RD2.
    Neurobiol Dis. 2019;124:36-45.
    PubMed     Abstract available

    March 2019
  79. SERGEANT N, Vingtdeux V, Eddarkaoui S, Gay M, et al
    New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease.
    Neurobiol Dis. 2019 Mar 27. pii: S0969-9961(18)30327.
    PubMed     Abstract available

  80. ADLIMOGHADDAM A, Snow WM, Stortz G, Perez C, et al
    Regional hypometabolism in the 3xTg mouse model of Alzheimer's disease.
    Neurobiol Dis. 2019;127:264-277.
    PubMed     Abstract available

    February 2019
  81. SABIR MS, Blauwendraat C, Ahmed S, Serrano GE, et al
    Assessment of APOE in atypical parkinsonism syndromes.
    Neurobiol Dis. 2019 Feb 21. pii: S0969-9961(19)30046.
    PubMed     Abstract available

  82. SHARMA N, Tramutola A, Lanzillotta C, Arena A, et al
    Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease.
    Neurobiol Dis. 2019;125:176-189.
    PubMed     Abstract available

    January 2019
  83. ELFAKHRI KH, Abdallah IM, Brannen AD, Kaddoumi A, et al
    Multi-faceted therapeutic strategy for treatment of Alzheimer's disease by concurrent administration of etodolac and alpha-tocopherol.
    Neurobiol Dis. 2019;125:123-134.
    PubMed     Abstract available

  84. LOWE SA, Usowicz MM, Hodge JJL
    Neuronal overexpression of Alzheimer's disease and down's syndrome associated DYRK1A/minibrain gene alters motor decline, neurodegeneration and synaptic plasticity in Drosophila.
    Neurobiol Dis. 2019;125:107-114.
    PubMed     Abstract available

  85. SHARMAN MJ, Gyengesi E, Liang H, Chatterjee P, et al
    Assessment of diets containing curcumin, epigallocatechin-3-gallate, docosahexaenoic acid and alpha-lipoic acid on amyloid load and inflammation in a male transgenic mouse model of Alzheimer's disease: Are combinations more effective?
    Neurobiol Dis. 2019 Jan 2. pii: S0969-9961(18)30770.
    PubMed     Abstract available

    December 2018
  86. RYSKAMP D, Wu L, Wu J, Kim D, et al
    Pridopidine stabilizes mushroom spines in mouse models of Alzheimer's disease by acting on the sigma-1 receptor.
    Neurobiol Dis. 2018 Dec 27. pii: S0969-9961(18)30595.
    PubMed     Abstract available

  87. CHANDRA S, Roy A, Jana M, Pahan K, et al
    Cinnamic acid activates PPARalpha to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model.
    Neurobiol Dis. 2018 Dec 19. pii: S0969-9961(18)30705.
    PubMed     Abstract available

  88. MARTTINEN M, Paananen J, Neme A, Mitra V, et al
    A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology.
    Neurobiol Dis. 2018 Dec 14. pii: S0969-9961(18)30479.
    PubMed     Abstract available

    November 2018
  89. ANCKAERTS C, Blockx I, Summer P, Michael J, et al
    Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer's Disease: A longitudinal MRI study.
    Neurobiol Dis. 2018;124:93-107.
    PubMed     Abstract available

    October 2018
  90. ASAVAPANUMAS N, Brawek B, Martus P, Garaschuk O, et al
    Role of intracellular Ca(2+) stores for an impairment of visual processing in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2018 Oct 23. pii: S0969-9961(18)30324.
    PubMed     Abstract available

  91. BARROETA-ESPAR I, Weinstock LD, Perez-Nievas BG, Meltzer AC, et al
    Distinct cytokine profiles in human brains resilient to Alzheimer's pathology.
    Neurobiol Dis. 2018 Oct 15. pii: S0969-9961(18)30713.
    PubMed     Abstract available

    September 2018
  92. GAUBA E, Chen H, Guo L, Du H, et al
    Cyclophilin D deficiency attenuates mitochondrial F1Fo ATP synthase dysfunction via OSCP in Alzheimer's disease.
    Neurobiol Dis. 2018 Sep 25. pii: S0969-9961(18)30499.
    PubMed     Abstract available

  93. TOURNIER BB, Tsartsalis S, Rigaud D, Fossey C, et al
    TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer's disease.
    Neurobiol Dis. 2018 Sep 24. pii: S0969-9961(18)30622.
    PubMed     Abstract available

    July 2018
  94. TRAMUTOLA A, Triani F, Di Domenico F, Barone E, et al
    Poly-ubiquitin profile in Alzheimer disease brain.
    Neurobiol Dis. 2018 Jul 9. pii: S0969-9961(18)30211.
    PubMed     Abstract available

  95. SMITH LA, McMahon LL
    Corrigendum to "Deficits in synaptic function occur at medial perforant path-dentate granule cell synapses prior to Schaffer collateral-CA1 pyramidal cell synapses in the novel TgF344-Alzheimer's Disease Rat Model" [Neurobiology of Disease Volume 110,
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    June 2018
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    Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study.
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    Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.
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  98. SILVA AC, Lemos C, Goncalves FQ, Pliassova AV, et al
    Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease.
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  99. HANFELT JJ, Peng L, Goldstein FC, Lah JJ, et al
    Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center.
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    Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease.
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    March 2018
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    Behavioral and SCN neurophysiological disruption in the Tg-SwDI mouse model of Alzheimer's disease.
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    Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease.
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    February 2018
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    NLRP3-dependent synaptic plasticity deficit in an Alzheimer's disease amyloidosis model in vivo.
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  104. SALAS IH, Weerasekera A, Ahmed T, Callaerts-Vegh Z, et al
    High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease.
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    January 2018
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    Human amyloid beta peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans.
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    December 2017
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    SUMO1 impact on Alzheimer disease pathology in an amyloid-depositing mouse model.
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    November 2017
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    Deficits in synaptic function occur at medial perforant path-granule cell synapses prior to Schaffer collateral-CA1 pyramidal cell synapses in the novel TgF344-Alzheimer's Disease Rat Model.
    Neurobiol Dis. 2017 Nov 30. pii: S0969-9961(17)30275.
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    August 2017
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    Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease.
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    July 2017
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    Ablating ErbB4 in PV neurons attenuates synaptic and cognitive deficits in an animal model of Alzheimer's disease.
    Neurobiol Dis. 2017 Jul 3. pii: S0969-9961(17)30153.
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    June 2017
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    Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
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    May 2017
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    Immunization with Bacillus Calmette-Guerin (BCG) alleviates neuroinflammation and cognitive deficits in APP/PS1 mice via the recruitment of inflammation-resolving monocytes to the brain.
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    October 2016
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    Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease.
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    The dynamic mechanism of presenilin-1 function: Sensitive gate dynamics and loop unplugging control protein access.
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