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Articles published in Blood

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    March 2023
  1. AYOUB PG, Kohn DB
    beta-Thalassemia: all about that base, no cutting.
    Blood. 2023;141:1098-1099.

  2. MATSON DR, Matkovic E
    Peripheral erythrophagocytosis in paroxysmal cold hemoglobinuria.
    Blood. 2023;141:1233.

  3. HARDOUIN G, Antoniou P, Martinucci P, Felix T, et al
    Adenine base editor-mediated correction of the common and severe IVS1-110 (G>A) beta-thalassemia mutation.
    Blood. 2023;141:1169-1179.
    PubMed     Abstract available

  4. Ludwig LS, Lareau CA, Bao EL, et al. Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1. Blood. 2022;139(16):2534-2546.
    Blood. 2023;141:1094.

  5. FAKHOURI F, Schwotzer N, Fremeaux-Bacchi V
    How I diagnose and treat atypical hemolytic uremic syndrome.
    Blood. 2023;141:984-995.
    PubMed     Abstract available

    February 2023
  6. OYEDEJI CI, Artz AS, Cohen HJ
    How I Treat Anemia in Older Adults.
    Blood. 2023 Feb 24:blood.2022017626. doi: 10.1182/blood.2022017626.
    PubMed     Abstract available

    Hydroxyurea: how much is enough?
    Blood. 2023;141:813-814.

  8. Camaschella C. Iron deficiency. Blood. 2019;133(1):30-39.
    Blood. 2023;141:682.

    January 2023
  9. FATTIZZO B, Bortolotti M, Fantini NN, Glenthoj A, et al
    Blood. 2023 Jan 27:blood.2022018890. doi: 10.1182/blood.2022018890.
    PubMed     Abstract available

  10. WOOD JC
    Anemia and brain hypoxia.
    Blood. 2023;141:327-328.

  11. Barcellini W, Fattizzo B. How I treat warm autoimmune hemolytic anemia. Blood. 2021;137(10):1283-1294.
    Blood. 2023;141:438-439.

  12. PARROW NL, Fleming RE
    Transferrin receptor 1: keeper of HFE.
    Blood. 2023;141:332-333.

  13. TARFI S, Badaoui B
    Four genetic red cell disorders in one.
    Blood. 2023;141:436.

  14. XIAO X, Moschetta GA, Xu Y, Fisher AL, et al
    Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in beta-thalassemia.
    Blood. 2023;141:422-432.
    PubMed     Abstract available

    Ups and downs in the treatment of sickle cell disease.
    Blood. 2023;141:125-127.

  16. DAS NK, Shah YM
    (De)ironing out sickle cell disease.
    Blood. 2023;141:129-130.

  17. KARAMATIC CREW V, Tilley LA, Satchwell TJ, AlSubhi SA, et al
    Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens.
    Blood. 2023;141:135-146.
    PubMed     Abstract available

  18. CURTIS SA, Novelli EM
    Is CBD ready for prime time in sickle cell disease?
    Blood. 2023;141:132-133.

  19. LI H, Kazmi JS, Lee S, Zhang D, et al
    Dietary iron restriction protects against vaso-occlusion and organ damage in murine sickle cell disease.
    Blood. 2023;141:194-199.
    PubMed     Abstract available

  20. CHERUKURY HM, Argueta DA, Garcia N, Fouda R, et al
    Cannabidiol attenuates hyperalgesia in a mouse model of sickle cell disease.
    Blood. 2023;141:203-208.

  21. DAMPIER CD, Telen MJ, Wun T, Brown RC, et al
    A randomized clinical trial of the efficacy and safety of rivipansel for sickle cell vaso-occlusive crisis.
    Blood. 2023;141:168-179.
    PubMed     Abstract available

  22. GROARKE EM, Feng X, Aggarwal N, Manley AL, et al
    Efficacy of JAK1/2 inhibition in murine immune bone marrow failure.
    Blood. 2023;141:72-89.
    PubMed     Abstract available

  23. GRIFFIN M, Muus P, Munir T, Nagumantry S, et al
    Experience of compassionate-use pegcetacoplan for paroxysmal nocturnal hemoglobinuria.
    Blood. 2023;141:116-120.

    December 2022

  24. Galli A, Todisco G, Catamo E, et al. Relationship between clone metrics and clinical outcome in clonal cytopenia. Blood. 2021;138(11):965-976.
    Blood. 2022;140:2858.

  25. SULLIVAN JC, Comenzo R
    Peripheral agglutination and hemolytic anemia following minor ABO-mismatch hematopoietic progenitor cell transplantation.
    Blood. 2022;140:2412.

    November 2022
  26. MORIN C, Sharma A, Selukar S, Beasley G, et al
    Diffuse Myocardial Fibrosis Occurs in Young Patients with Sickle Cell Anemia Despite Early Disease Modifying Therapy.
    Blood. 2022 Nov 28:blood.2022018209. doi: 10.1182/blood.2022018209.

    Platelets: out of shape and misbehaving.
    Blood. 2022;140:2188-2190.

  28. KUTLAR A
    A-two to the rescue.
    Blood. 2022;140:2187-2188.

  29. ZHU J, Li H, Aerbajinai W, Kumkhaek C, et al
    Kruppel-like factor 1-GATA1 fusion protein improves the sickle cell disease phenotype in mice both in vitro and in vivo.
    Blood. 2022;140:2276-2289.
    PubMed     Abstract available

  30. OLUPOT-OLUPOT P, Tomlinson G, Williams TN, Tshilolo LMM, et al
    Hydroxyurea is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa.
    Blood. 2022 Nov 14. pii: 487110. doi: 10.1182/blood.2022017051.
    PubMed     Abstract available

    RBC, heal thyself: PK activators in SCD.
    Blood. 2022;140:2005-2006.

  32. XU JZ, Conrey A, Frey I, Gwaabe E, et al
    A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease.
    Blood. 2022;140:2053-2062.
    PubMed     Abstract available

  33. GIBB DR, Hudson KE
    Sickle cell inflammation: is HbS the answer?
    Blood. 2022;140:1921-1923.

  34. ALLALI S, Rignault-Bricard R, de Montalembert M, Taylor M, et al
    HbS promotes TLR4-mediated monocyte activation and proinflammatory cytokine production in sickle cell disease.
    Blood. 2022;140:1972-1982.
    PubMed     Abstract available

  35. ABDULLAHI S, Sunusi SM, Abba MS, Sani S, et al
    Hydroxyurea for Secondary Stroke Prevention in Children with Sickle Cell Anemia in Nigeria:a Randomized Controlled Trial.
    Blood. 2022 Nov 2. pii: 486968. doi: 10.1182/blood.2022016620.
    PubMed     Abstract available

    October 2022
  36. CARSON JL, Brittenham GM
    How I Treat Anemia with Red Blood Cell Transfusion and Iron.
    Blood. 2022 Oct 31. pii: 486955. doi: 10.1182/blood.2022018521.
    PubMed     Abstract available

  37. KHASABOVA II, Juliette J, Rogness VM, Khasabov SG, et al
    A model of painful vaso-occlusive crisis in mice with sickle cell disease.
    Blood. 2022;140:1826-1830.

  38. CARSETTI R, Agrati C, Pinto VM, Gianesin B, et al
    Premature aging of the immune system affects the response to SARS-CoV-2 mRNA vaccine in beta-thalassemia: role of an additional dose.
    Blood. 2022;140:1735-1738.

    September 2022
  39. PECKER LH, Ellsworth P
    Raise the roof, build the floor.
    Blood. 2022;140:1453-1455.

  40. HEENEY MM, Abboud MR, Githanga J, Inusa BPD, et al
    Ticagrelor vs placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study.
    Blood. 2022;140:1470-1481.
    PubMed     Abstract available

  41. THEIN SL, Sachdev V
    Diffuse myocardial fibrosis as an SCD biomarker.
    Blood. 2022;140:1191-1192.

  42. Tumburu L, Ghosh-Choudhary S, Seifuddin FT, et al. Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease. Blood. 2021;137(22):3116-3126.
    Blood. 2022;140:1327.

  43. TORRES LS, Hidalgo A
    NETs in sickle cell disease, quo vadis?
    Blood. 2022;140:938-939.

  44. CHONAT S, Stowell SR
    A virtuosic CADENZA played by sutimlimab.
    Blood. 2022;140:933-935.

  45. VATS R, Kaminski TW, Brzoska T, Leech JA, et al
    Liver-to-lung microembolic NETs promote gasdermin D-dependent inflammatory lung injury in sickle cell disease.
    Blood. 2022;140:1020-1037.
    PubMed     Abstract available

  46. ROTH A, Berentsen S, Barcellini W, D'Sa S, et al
    Sutimlimab in patients with cold agglutinin disease: results of the randomized placebo-controlled phase 3 CADENZA trial.
    Blood. 2022;140:980-991.
    PubMed     Abstract available

    August 2022
  47. HULBERT ML, Fields ME, Guilliams KP, Bijlani P, et al
    Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease.
    Blood. 2022 Aug 30. pii: 486449. doi: 10.1182/blood.2022016618.
    PubMed     Abstract available

    Playing with fire: unrecognized AA genetic predisposition.
    Blood. 2022;140:805-807.

  49. MARQUES O, Weiss G, Muckenthaler MU
    The role of iron in chronic inflammatory diseases - from mechanisms to treatment options in Anemia of Inflammation.
    Blood. 2022 Aug 22. pii: 486362. doi: 10.1182/blood.2021013472.
    PubMed     Abstract available

  50. PARROW NL, Fleming RE
    Isn't it ironic: better RBCs by blocking iron.
    Blood. 2022;140:669-670.

  51. Vats R, Kaminski TW, Ju E-M, et al. P-selectin deficiency promotes liver senescence in sickle cell disease mice. Blood. 2021;137(19):2676-2680.
    Blood. 2022;140:794.

  52. FATTIZZO B, Cecchi N, Bortolotti M, Giordano G, et al
    Thrombopoietin receptor agonists in adult Evans syndrome: an international multicenter experience.
    Blood. 2022;140:789-792.

  53. NYFFENEGGER N, Zennadi R, Kalleda N, Flace A, et al
    The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease.
    Blood. 2022;140:769-781.
    PubMed     Abstract available

  54. DOKAL I, Tummala H, Vulliamy T
    Inherited bone marrow failure in the pediatric patient.
    Blood. 2022;140:556-570.
    PubMed     Abstract available

    July 2022
  55. PINCEZ T, Aladjidi N, Heritier S, Garnier N, et al
    Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias.
    Blood. 2022;140:253-261.
    PubMed     Abstract available

  56. NISS O, Detterich JA, Wood JC, Coates TD, et al
    Early initiation of disease-modifying therapy can impede or prevent diffuse myocardial fibrosis in sickle cell anemia.
    Blood. 2022 Jul 20. pii: 485971. doi: 10.1182/blood.2021015303.

  57. MCREYNOLDS LJ, Rafati M, Wang Y, Ballew BJ, et al
    Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes.
    Blood. 2022 Jul 1. pii: 485762. doi: 10.1182/blood.2022016508.
    PubMed     Abstract available

    June 2022
  58. LANZKRON S, Pecker L
    Pain without gain: steroids and sickle crisis.
    Blood. 2022;139:3678-3679.

  59. THAKRAL B, Bueso-Ramos CE
    Unexpected presentation of cold agglutinin syndrome with B-acute lymphoblastic leukemia.
    Blood. 2022;139:3778.

  60. WALTER O, Cougoul P, Maquet J, Bartolucci P, et al
    Risk of vaso-occlusive episode after exposure to corticosteroids in patients with sickle cell disease.
    Blood. 2022;139:3771-3777.
    PubMed     Abstract available

  61. KROLL MH, Rojas-Hernandez C, Yee C
    Hematologic complications of immune checkpoint inhibitors.
    Blood. 2022;139:3594-3604.
    PubMed     Abstract available

  62. GAVRIILAKI E, de Latour RP, Risitano AM
    Advancing therapeutic complement inhibition in hematologic diseases: PNH and beyond.
    Blood. 2022;139:3571-3582.
    PubMed     Abstract available

  63. GERBER GF, Brodsky RA
    Pegcetacoplan for paroxysmal nocturnal hemoglobinuria.
    Blood. 2022;139:3361-3365.
    PubMed     Abstract available

  64. DOTY RT, Fan X, Young DJ, Liang J, et al
    Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis.
    Blood. 2022;139:3439-3449.
    PubMed     Abstract available

    May 2022
  65. ISKANDER D, Warren AJ
    Turning up the HEAT(R3) in Diamond-Blackfan anemia.
    Blood. 2022;139:3101-3102.

    Anemia of inflammation is all the RAGE.
    Blood. 2022;139:3106-3107.

  67. XU JZ, Thein SL
    Revisiting anemia in sickle cell disease and finding the balance with therapeutic approaches.
    Blood. 2022;139:3030-3039.
    PubMed     Abstract available

    April 2022
    Extinguishing the fire in sickle cell anemia.
    Blood. 2022;139:2578-2580.

  69. DAS NK, Jain C, Sankar A, Schwartz AJ, et al
    Modulation of the HIF2alpha-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis.
    Blood. 2022;139:2547-2552.
    PubMed     Abstract available

  70. WHITE NJ
    What causes malaria anemia?
    Blood. 2022;139:2268-2269.

  71. MAHAMAR A, Gonzales Hurtado PA, Morrison R, Boone R, et al
    Plasma biomarkers of hemoglobin loss in Plasmodium falciparum-infected children identified by quantitative proteomics.
    Blood. 2022;139:2361-2376.
    PubMed     Abstract available

  72. NWOGBO OV, Loghavi S
    Essential thrombocythemia complicating hemoglobin SC disease and presenting with priapism.
    Blood. 2022;139:2258.

  73. WANG M, Dingler FA, Patel KJ
    Genotoxic aldehydes in the hematopoietic system.
    Blood. 2022;139:2119-2129.
    PubMed     Abstract available

  74. TOPFER SK, Feng R, Huang P, Ly LC, et al
    Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
    Blood. 2022;139:2107-2118.
    PubMed     Abstract available

    March 2022
    RNA missplicing and ring sideroblasts in MDS.
    Blood. 2022;139:1933-1935.

  76. WOOD JC
    Pulmonary hypertension in thalassemia: a call to action.
    Blood. 2022;139:1937-1938.

  77. PINTO VM, Musallam KM, Derchi G, Graziadei G, et al
    Mortality in beta-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization.
    Blood. 2022;139:2080-2083.

  78. SCHMIDT CQ, Schrezenmeier H, Kavanagh D
    Complement and the prothrombotic state.
    Blood. 2022;139:1954-1972.
    PubMed     Abstract available

  79. DOSUNMU-OGUNBI A, Yuan S, Reynolds M, Giordano L, et al
    SOD2 V16A amplifies vascular dysfunction in sickle cell patients by curtailing mitochondria complex IV activity.
    Blood. 2022;139:1760-1765.
    PubMed     Abstract available

    Mitochondrial function in sickle cell disease.
    Blood. 2022;139:1616-1617.

  81. WONTAKAL SN, Britto M, Zhang H, Han Y, et al
    RACGAP1 variants in a sporadic case of CDA III implicate the dysfunction of centralspindlin as the basis of the disease.
    Blood. 2022;139:1413-1418.

    February 2022
  82. REES DC, Kilinc Y, Unal S, Dampier CD, et al
    A randomized, placebo-controlled, double-blind trial of canakinumab in children and young adults with sickle cell anemia.
    Blood. 2022 Feb 28. pii: 484189. doi: 10.1182/blood.2021013674.
    PubMed     Abstract available

  83. O'DONOHUE MF, Da Costa LM, Lezzerini M, Unal S, et al
    HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia.
    Blood. 2022 Feb 25. pii: 484180. doi: 10.1182/blood.2021011846.
    PubMed     Abstract available

    Anemia in the pediatric patient.
    Blood. 2022 Feb 25. pii: 484178. doi: 10.1182/blood.2020006479.
    PubMed     Abstract available

  85. MENON AV, Liu J, Tsai HP, Zeng L, et al
    Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease.
    Blood. 2022;139:936-941.
    PubMed     Abstract available

    January 2022
  86. NEUMANN NM, Wen KW
    Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts, thrombocytosis, and mutated JAK2/SF3B1 without anemia.
    Blood. 2022;139:466.

  87. RAO VK
    Evans syndrome: pathology and genomic hubris.
    Blood. 2022;139:312-313.

  88. KUMAR D, Prince C, Bennett CM, Briones M, et al
    T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome.
    Blood. 2022;139:369-383.
    PubMed     Abstract available

  89. DULMOVITS BM, Tang Y, Papoin J, He M, et al
    HMGB1-Mediated Restriction of EPO Signaling Contributes to Anemia of Inflammation.
    Blood. 2022 Jan 18. pii: 483547. doi: 10.1182/blood.2021012048.
    PubMed     Abstract available

  90. LUDWIG L, Lareau CA, Bao EL, Liu N, et al
    A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1.
    Blood. 2022 Jan 14. pii: 483530. doi: 10.1182/blood.2021013753.
    PubMed     Abstract available

  91. DHUNPUTH C, Ducassou S, Fernandes H, Picard C, et al
    Abatacept is useful in autoimmune cytopenia with immunopathologic manifestations caused by CTLA-4 defects.
    Blood. 2022;139:300-304.

    December 2021
  92. PAGLIUCA S, Gurnari C, Awada H, Kishtagari A, et al
    The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders.
    Blood. 2021;138:2781-2798.
    PubMed     Abstract available

  93. TANG A, Strat AN, Rahman M, Zhang H, et al
    Murine bone marrow mesenchymal stromal cells have reduced hematopoietic maintenance ability in sickle cell disease.
    Blood. 2021;138:2570-2582.
    PubMed     Abstract available

  94. PECKER L, Hussain S, Mahesh J, Varadhan R, et al
    Diminished ovarian reserve in young women with sickle cell anemia.
    Blood. 2021 Dec 5. pii: 482897. doi: 10.1182/blood.2021012756.

  95. MARTIN MERINERO H, Zhang Y, Arjona E, Del Angel G, et al
    Functional characterization of 105 factor H variants associated with aHUS: lessons for variant classification.
    Blood. 2021;138:2185-2201.
    PubMed     Abstract available

    November 2021
  96. DUCHEMANN B, Lazarian G
    Post-SARS-CoV-2 vaccination acute hemolysis in an older man: don't forget to look at the blood smear.
    Blood. 2021;138:2153.

  97. PINCEZ T, Lee SSK, Ilboudo Y, Preuss M, et al
    Clonal hematopoiesis in sickle cell disease.
    Blood. 2021;138:2148-2152.

    Control of hemolysis in patients with PNH.
    Blood. 2021;138:1908-1910.

  99. KULASEKARARAJ AG, Risitano AM, Maciejewski JP, Notaro R, et al
    Phase 2 study of danicopan in patients with paroxysmal nocturnal hemoglobinuria with an inadequate response to eculizumab.
    Blood. 2021;138:1928-1938.
    PubMed     Abstract available

  100. EL SISSY C, Saldman A, Zanetta G, Martins PV, et al
    COVID-19 as a potential trigger of complement-mediated atypical HUS.
    Blood. 2021;138:1777-1782.

  101. FENG Y, Feng W
    Numerous ring sideroblasts in chronic neutrophilic leukemia.
    Blood. 2021;138:1783.

  102. ZAIMOKU Y, Patel BA, Adams SD, Shalhoub RN, et al
    HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia.
    Blood. 2021 Nov 1. pii: 477734. doi: 10.1182/blood.2021012895.
    PubMed     Abstract available

    September 2021
  103. HENRY ER, Metaferia B, Li Q, Harper J, et al
    Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
    Blood. 2021;138:1172-1181.
    PubMed     Abstract available

  104. LIU Y, Pal M, Bao W, Shi PA, et al
    Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease.
    Blood. 2021;138:1162-1171.
    PubMed     Abstract available

  105. IRELAND RM, Rees DC
    Two brothers with a novel KLF1 mutation.
    Blood. 2021;138:1087.

  106. ABRAHAM AA, Tisdale JF
    Gene therapy for sickle cell disease: moving from the bench to the bedside.
    Blood. 2021;138:932-941.
    PubMed     Abstract available

    Introduction to a review series on gene therapy and gene editing for sickle cell disease and hemophilia.
    Blood. 2021;138:913.

  108. PATEL BA, Groarke EM, Lotter J, Shalhoub RN, et al
    Long-term outcomes in severe aplastic anemia patients treated with immunosuppression and eltrombopag: a phase 2 study.
    Blood. 2021 Sep 15. pii: 476916. doi: 10.1182/blood.2021012130.
    PubMed     Abstract available

    August 2021
  109. COCHRAN T, Li W
    Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation.
    Blood. 2021;138:738.

  110. XU Z, Mueller R
    Myelodysplastic pure red cell aplasia.
    Blood. 2021;138:500.

    July 2021
  111. JALINK M, Berentsen S, Castillo J, Treon SPP, et al
    Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome.
    Blood. 2021 Jul 22. pii: 476451. doi: 10.1182/blood.2021012039.

  112. RICE L, Schwartz MR
    Sickle cell hepatopathy with spur cell anemia.
    Blood. 2021;138:283.

  113. GERBER GF, Yuan X, Yu J, Cher BAY, et al
    COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:3670-3673.

    June 2021
  114. MORENO C
    Autoimmune cytopenia and CLL ride together.
    Blood. 2021;137:3464-3465.

  115. MARTIN MERINERO H, Subias M, Pereda A, Gomez-Rubio E, et al
    Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases.
    Blood. 2021;137:3484-3494.
    PubMed     Abstract available

  116. REJESKI K, Perez Perez A, Sesques P, Hoster E, et al
    CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma.
    Blood. 2021 Jun 24. pii: 476241. doi: 10.1182/blood.2020010543.
    PubMed     Abstract available

  117. PSATHA N, Georgakopoulou A, Li C, Nandakumar V, et al
    Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo.
    Blood. 2021 Jun 4. pii: 476068. doi: 10.1182/blood.2020010020.
    PubMed     Abstract available

  118. RARICK KR, Pritchard KA
    The sickle erythrocyte yields another DAMP.
    Blood. 2021;137:3010-3011.

  119. JONES RJ, DeBaun MR
    Leukemia after gene therapy for sickle cell disease: insertional mutagenesis, busulfan, both or neither.
    Blood. 2021 Jun 3. pii: 476065. doi: 10.1182/blood.2021011488.
    PubMed     Abstract available

  120. TUMBURU L, Ghosh-Choudhary S, Seifuddin FT, Barbu EA, et al
    Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease.
    Blood. 2021;137:3116-3126.
    PubMed     Abstract available

    May 2021
  121. RAB MAE, Bos J, van Oirschot BA, van Straaten S, et al
    Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy.
    Blood. 2021;137:2997-3001.

  122. MANWANI D
    P-selectin and sickle cell disease: a balancing act.
    Blood. 2021;137:2573-2574.

  123. VATS R, Kaminski TW, Ju EM, Brozska T, et al
    P-selectin deficiency promotes liver senescence in sickle cell disease mice.
    Blood. 2021;137:2676-2680.
    PubMed     Abstract available

    Eculizumab and aHUS: to stop or not.
    Blood. 2021;137:2419-2420.

  125. FAKHOURI F, Fila M, Hummel A, Ribes D, et al
    Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study.
    Blood. 2021;137:2438-2449.
    PubMed     Abstract available

    April 2021
  126. CERCAMONDI CI, Stoffel N, Moretti D, Zoller T, et al
    Iron homeostasis during anemia of inflammation: a prospective study in patients with tuberculosis.
    Blood. 2021 Apr 19. pii: 475787. doi: 10.1182/blood.2020010562.
    PubMed     Abstract available

  127. SHAH N
    ELIPSIS: developing tools to better understand VOC in SCD.
    Blood. 2021;137:1987-1988.

  128. GURNARI C, Maciejewski JP
    How I manage acquired pure red cell aplasia in adults.
    Blood. 2021;137:2001-2009.
    PubMed     Abstract available

  129. PITTMAN DD, Hines PC, Beidler D, Rybin D, et al
    Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers.
    Blood. 2021;137:2010-2020.
    PubMed     Abstract available

  130. TURNIS ME, Kaminska E, Smith KH, Kartchner BJ, et al
    Requirement for antiapoptotic MCL-1 during early erythropoiesis.
    Blood. 2021;137:1945-1958.
    PubMed     Abstract available

    March 2021
  131. GONG Y, Zhang X, Zhang Q, Zhang Y, et al
    A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the gamma-globin gene in beta-thalassemia.
    Blood. 2021;137:1652-1657.
    PubMed     Abstract available

  132. ZHU C, Lian Y, Wang C, Wu P, et al
    Single-cell transcriptomics dissects hematopoietic cell destruction and T cell engagement in aplastic anemia.
    Blood. 2021 Mar 24. pii: 475591. doi: 10.1182/blood.2020008966.
    PubMed     Abstract available

  133. HOSOKAWA K, Mizumaki H, Yoroidaka T, Maruyama H, et al
    HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia.
    Blood. 2021 Mar 22. pii: 475586. doi: 10.1182/blood.2020010586.

    Less (Fe) is more (Hb) in SCA.
    Blood. 2021;137:1446-1447.

  135. ANSARI J, Senchenkova EY, Vital SA, Al-Yafeai Z, et al
    Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease.
    Blood. 2021;137:1538-1549.
    PubMed     Abstract available

  136. ELDAR D, Ganzel C
    Erythrophagocytosis in a young adult with mycoplasma pneumonia-induced paroxysmal cold hemoglobinuria.
    Blood. 2021;137:1432.

    How I treat cold agglutinin disease.
    Blood. 2021;137:1295-1303.
    PubMed     Abstract available

    How I treat paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:1304-1309.
    PubMed     Abstract available

  139. ZHABYEYEV P, Oudit GY
    Sickle cell disease, interleukin-18, and arrhythmias.
    Blood. 2021;137:1138-1139.

  140. GUPTA A, Fei YD, Kim TY, Xie A, et al
    IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.
    Blood. 2021;137:1208-1218.
    PubMed     Abstract available

    February 2021
  141. WACHTER F, Archer NM
    Autoimmune hemolytic anemia complicated by parvovirus infection.
    Blood. 2021;137:1130.

  142. GU Y, Yang R, Yang Y, Zhao Y, et al
    IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.
    Blood. 2021;137:945-958.
    PubMed     Abstract available

    Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
    Blood. 2021;137:888-895.
    PubMed     Abstract available

  144. WARE RE, Dertinger SD
    There's safety in numbers.
    Blood. 2021;137:729-731.

  145. REES DC
    Hydroxyurea: coming to conclusions on safety.
    Blood. 2021;137:728-729.

  146. GILLE AS, Pondarre C, Dalle JH, Bernaudin F, et al
    Hydroxyurea does not affect the spermatogonial pool in prepubertal patients with sickle cell disease.
    Blood. 2021;137:856-859.

  147. JOSEPH L, Jean C, Manceau S, Chalas C, et al
    Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
    Blood. 2021;137:826-829.
    PubMed     Abstract available

  148. SHENG Y, Ma R, Yu C, Wu Q, et al
    Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
    Blood. 2021;137:610-623.
    PubMed     Abstract available

    January 2021
  149. BADAT M, Davies JOJ, Fisher CA, Downes DJ, et al
    A remarkable case of HbH disease illustrates the relative contributions of the alpha-globin enhancers to gene expression.
    Blood. 2021;137:572-575.

  150. DEANS AJ
    Fanconi anemia, put to sleep.
    Blood. 2021;137:286-288.

  151. THOMAS M, Scully M
    How I Treat Microangiopathic Hemolytic Anemia in Patients with Cancer.
    Blood. 2021 Jan 21. pii: 475029. doi: 10.1182/blood.2019003810.
    PubMed     Abstract available

  152. CAZZOLA M
    Introduction to a How I Treat Series on Acquired Hemolytic Anemia.
    Blood. 2021 Jan 21. pii: 475027. doi: 10.1182/blood.2020009747.

  153. BARCELLINI W, Fattizzo B
    How I treat warm autoimmune hemolytic anemia.
    Blood. 2021 Jan 21. pii: 475030. doi: 10.1182/blood.2019003808.
    PubMed     Abstract available

  154. PIRENNE F
    Heme control to major B (cell): are you listening?
    Blood. 2021;137:153-154.

  155. PAL M, Bao W, Wang R, Liu Y, et al
    Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease.
    Blood. 2021;137:269-280.
    PubMed     Abstract available

  156. MU A, Hira A, Niwa A, Osawa M, et al
    Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
    Blood. 2021 Jan 12. pii: 474923. doi: 10.1182/blood.2020009111.
    PubMed     Abstract available

  157. SALIB C, Hussein S
    A case of hairy cell leukemia with markedly hypocellular marrow mimicking aplastic anemia.
    Blood. 2021;137:142.

    December 2020
  158. SICA M, Pellecchia A, De Angioletti M, Caocci G, et al
    Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH.
    Blood. 2020;136:3082-3085.

  159. MARIANI R, Liu H
    Severe transient pancytopenia with dyserythropoiesis and dysmegakaryopoiesis in COVID-19-associated MIS-C.
    Blood. 2020;136:2964.

  160. ARORA S, Ganapathi KA
    Prominent pseudo-Gaucher cells in a patient with beta-thalassemia intermedia and plasma cell myeloma.
    Blood. 2020;136:2839.

  161. PARROW NL, Violet PC, Ajit George N, Ali F, et al
    Dietary Iron Restriction Improves Markers of Disease Severity in Murine Sickle Cell Anemia.
    Blood. 2020 Dec 8. pii: 474426. doi: 10.1182/blood.2020006919.

    November 2020
    A simple Rx for congenital erythropoietic porphyria.
    Blood. 2020;136:2371-2372.

    October 2020
  163. DEWARRAT N, Blum S
    Heavy metal.
    Blood. 2020;136:1993.

    September 2020
  164. ARJONA E, Huerta A, Goicoechea de Jorge E, Rodriguez de Cordoba S, et al
    Familial risk of developing atypical hemolytic-uremic syndrome.
    Blood. 2020;136:1558-1561.

  165. KIM-SHAPIRO DB, Gladwin MT
    Arginine for mitochondrial oxidative enzymopathy.
    Blood. 2020;136:1376-1378.

  166. MORRIS CR, Brown LAS, Reynolds M, Dampier CD, et al
    Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain.
    Blood. 2020;136:1402-1406.
    PubMed     Abstract available

  167. LUZZATTO L, Ally M, Notaro R
    Glucose-6-phosphate dehydrogenase deficiency.
    Blood. 2020;136:1225-1240.
    PubMed     Abstract available

  168. SCHELL B, Fenneteau O
    Brandalise syndrome: a rare inclusion cell disease.
    Blood. 2020;136:1373.

  169. RISINGER M, Kalfa TA
    Red cell membrane disorders: structure meets function.
    Blood. 2020;136:1250-1261.
    PubMed     Abstract available

  170. CAZZOLA M
    Introduction to a review series on inherited anemias.
    Blood. 2020;136:1215-1216.

  171. IOLASCON A, Andolfo I, Russo R
    Congenital dyserythropoietic anemias.
    Blood. 2020;136:1274-1283.
    PubMed     Abstract available

  172. GRACE RF, Barcellini W
    Management of pyruvate kinase deficiency in children and adults.
    Blood. 2020;136:1241-1249.
    PubMed     Abstract available

  173. BROUSSE V, Connes P
    Vasomotor hyperresponsiveness in SCD.
    Blood. 2020;136:1120-1121.

  174. VELUSWAMY S, Shah P, Khaleel M, Thuptimdang W, et al
    Progressive vasoconstriction with sequential thermal stimulation indicates vascular dysautonomia in sickle cell disease.
    Blood. 2020;136:1191-1200.
    PubMed     Abstract available

    August 2020
  175. VOIT RA, Grace RF
    Pyruvate kinase deficiency in a newborn with extramedullary hematopoiesis in the skin.
    Blood. 2020;136:770.

    July 2020
    Targeting the bone marrow niche in hemoglobinopathies.
    Blood. 2020;136:529-531.

  177. BRAZAUSKAS R, Scigliuolo GM, Wang HL, Cappelli B, et al
    Risk score to predict event-free survival after hematopoietic cell transplant for sickle cell disease.
    Blood. 2020;136:623-626.
    PubMed     Abstract available

  178. ROTH A
    Do temperature and time matter in cold agglutinin disease?
    Blood. 2020;136:380-381.

  179. BERENTSEN S, Barcellini W, D'Sa S, Randen U, et al
    Cold agglutinin disease revisited: a multinational, observational study of 232 patients.
    Blood. 2020;136:480-488.
    PubMed     Abstract available

  180. KATO GJ
    Sickle particulars of microparticles.
    Blood. 2020;136:154-155.

  181. GARNIER Y, Ferdinand S, Garnier M, Cita KC, et al
    Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties.
    Blood. 2020;136:247-256.
    PubMed     Abstract available

  182. EVANS EL, Povstyan OV, De Vecchis D, Macrae F, et al
    RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis.
    Blood. 2020;136:140-144.

    June 2020
  183. KHAN R, Menard M, Jen CC, Chen X, et al
    Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP.
    Blood. 2020;135:2420-2424.
    PubMed     Abstract available

  184. CHEN BY, Song J, Hu CL, Chen SB, et al
    SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
    Blood. 2020;135:2271-2285.
    PubMed     Abstract available

  185. HUANG P, Peslak SA, Lan X, Khandros E, et al
    The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression.
    Blood. 2020;135:2121-2132.
    PubMed     Abstract available

    Sickle marrow: double, double toil and trouble.
    Blood. 2020;135:2017-2018.

  187. PARK SY, Matte A, Jung Y, Ryu J, et al
    Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion.
    Blood. 2020;135:2071-2084.
    PubMed     Abstract available

    May 2020
  188. KHANDROS E, Huang P, Peslak SA, Sharma M, et al
    Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
    Blood. 2020;135:1957-1968.
    PubMed     Abstract available

    Sickle cell vaso-occlusion: the clot thickens.
    Blood. 2020;135:1726-1727.

  190. SPARKENBAUGH EM, Chen C, Brzoska T, Nguyen J, et al
    Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease.
    Blood. 2020;135:1783-1787.
    PubMed     Abstract available

    April 2020
  191. SCHINDLER D, Kalb R
    Disease and mutation: correlations coming to fruition.
    Blood. 2020;135:1514-1515.

  192. APRILE A, Gulino A, Storto M, Villa I, et al
    Hematopoietic stem cell function in beta-thalassemia is impaired and is rescued by targeting the bone marrow niche.
    Blood. 2020 Apr 28. pii: 454666. doi: 10.1182/blood.2019002721.
    PubMed     Abstract available

  193. GHANNAM JY, Xu X, Maric I, Dillon L, et al
    Baseline TP53 mutations in adults with SCD developing myeloid malignancy following hematopoietic cell transplantation.
    Blood. 2020;135:1185-1188.

    March 2020
  194. SARAF SL
    Heme A1M'ed at the kidney in sickle cell disease.
    Blood. 2020;135:979-981.

  195. OFORI-ACQUAH SF, Hazra R, Orikogbo OO, Crosby D, et al
    Hemopexin deficiency promotes acute kidney injury in sickle cell disease.
    Blood. 2020;135:1044-1048.
    PubMed     Abstract available

    A complementary new drug for PNH.
    Blood. 2020;135:884-885.

  197. ROTH A, Nishimura JI, Nagy Z, Gaal-Weisinger J, et al
    The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria.
    Blood. 2020;135:912-920.
    PubMed     Abstract available

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