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COVID-19: Daily Top 10 Papers


  Anemia

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Articles published in Blood

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    November 2021
  1. EL SISSY C, Saldman A, Zanetta G, Martins PV, et al
    COVID-19 as a potential trigger of complement-mediated atypical HUS.
    Blood. 2021;138:1777-1782.
    PubMed    


  2. ZAIMOKU Y, Patel BA, Adams SD, Shalhoub RN, et al
    HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia.
    Blood. 2021 Nov 1. pii: 477734. doi: 10.1182/blood.2021012895.
    PubMed     Abstract available


    September 2021
  3. PATEL BA, Groarke EM, Lotter J, Shalhoub RN, et al
    Long-term outcomes in severe aplastic anemia patients treated with immunosuppression and eltrombopag: a phase 2 study.
    Blood. 2021 Sep 15. pii: 476916. doi: 10.1182/blood.2021012130.
    PubMed     Abstract available


    August 2021
  4. COCHRAN T, Li W
    Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation.
    Blood. 2021;138:738.
    PubMed    


    July 2021
  5. JALINK M, Berentsen S, Castillo J, Treon SPP, et al
    Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome.
    Blood. 2021 Jul 22. pii: 476451. doi: 10.1182/blood.2021012039.
    PubMed    


  6. RICE L, Schwartz MR
    Sickle cell hepatopathy with spur cell anemia.
    Blood. 2021;138:283.
    PubMed    


  7. GERBER GF, Yuan X, Yu J, Cher BAY, et al
    COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:3670-3673.
    PubMed    


    June 2021
  8. MORENO C
    Autoimmune cytopenia and CLL ride together.
    Blood. 2021;137:3464-3465.
    PubMed    


  9. RARICK KR, Pritchard KA
    The sickle erythrocyte yields another DAMP.
    Blood. 2021;137:3010-3011.
    PubMed    


    May 2021
  10. MANWANI D
    P-selectin and sickle cell disease: a balancing act.
    Blood. 2021;137:2573-2574.
    PubMed    


  11. BRODSKY RA
    Eculizumab and aHUS: to stop or not.
    Blood. 2021;137:2419-2420.
    PubMed    


    April 2021
  12. CERCAMONDI CI, Stoffel N, Moretti D, Zoller T, et al
    Iron homeostasis during anemia of inflammation: a prospective study in patients with tuberculosis.
    Blood. 2021 Apr 19. pii: 475787. doi: 10.1182/blood.2020010562.
    PubMed     Abstract available


  13. SHAH N
    ELIPSIS: developing tools to better understand VOC in SCD.
    Blood. 2021;137:1987-1988.
    PubMed    


  14. TURNIS ME, Kaminska E, Smith KH, Kartchner BJ, et al
    Requirement for antiapoptotic MCL-1 during early erythropoiesis.
    Blood. 2021;137:1945-1958.
    PubMed     Abstract available


    March 2021
  15. GONG Y, Zhang X, Zhang Q, Zhang Y, et al
    A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the gamma-globin gene in beta-thalassemia.
    Blood. 2021;137:1652-1657.
    PubMed     Abstract available


  16. ZHU C, Lian Y, Wang C, Wu P, et al
    Single-cell transcriptomics dissects hematopoietic cell destruction and T cell engagement in aplastic anemia.
    Blood. 2021 Mar 24. pii: 475591. doi: 10.1182/blood.2020008966.
    PubMed     Abstract available


  17. HOSOKAWA K, Mizumaki H, Yoroidaka T, Maruyama H, et al
    HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia.
    Blood. 2021 Mar 22. pii: 475586. doi: 10.1182/blood.2020010586.
    PubMed    


  18. BRUGNARA C
    Less (Fe) is more (Hb) in SCA.
    Blood. 2021;137:1446-1447.
    PubMed    


  19. ANSARI J, Senchenkova EY, Vital SA, Al-Yafeai Z, et al
    Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease.
    Blood. 2021;137:1538-1549.
    PubMed     Abstract available


  20. ELDAR D, Ganzel C
    Erythrophagocytosis in a young adult with mycoplasma pneumonia-induced paroxysmal cold hemoglobinuria.
    Blood. 2021;137:1432.
    PubMed    


  21. BERENTSEN S
    How I treat cold agglutinin disease.
    Blood. 2021;137:1295-1303.
    PubMed     Abstract available


  22. BRODSKY RA
    How I treat paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:1304-1309.
    PubMed     Abstract available


  23. ZHABYEYEV P, Oudit GY
    Sickle cell disease, interleukin-18, and arrhythmias.
    Blood. 2021;137:1138-1139.
    PubMed    


  24. GUPTA A, Fei YD, Kim TY, Xie A, et al
    IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.
    Blood. 2021;137:1208-1218.
    PubMed     Abstract available


    February 2021
  25. WACHTER F, Archer NM
    Autoimmune hemolytic anemia complicated by parvovirus infection.
    Blood. 2021;137:1130.
    PubMed    


  26. GU Y, Yang R, Yang Y, Zhao Y, et al
    IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.
    Blood. 2021;137:945-958.
    PubMed     Abstract available


  27. AL-SAMKARI H
    Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
    Blood. 2021;137:888-895.
    PubMed     Abstract available


  28. WARE RE, Dertinger SD
    There's safety in numbers.
    Blood. 2021;137:729-731.
    PubMed    


  29. REES DC
    Hydroxyurea: coming to conclusions on safety.
    Blood. 2021;137:728-729.
    PubMed    


  30. GILLE AS, Pondarre C, Dalle JH, Bernaudin F, et al
    Hydroxyurea does not affect the spermatogonial pool in prepubertal patients with sickle cell disease.
    Blood. 2021;137:856-859.
    PubMed    


  31. JOSEPH L, Jean C, Manceau S, Chalas C, et al
    Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
    Blood. 2021;137:826-829.
    PubMed     Abstract available


  32. SHENG Y, Ma R, Yu C, Wu Q, et al
    Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
    Blood. 2021;137:610-623.
    PubMed     Abstract available


    January 2021
  33. BADAT M, Davies JOJ, Fisher CA, Downes DJ, et al
    A remarkable case of HbH disease illustrates the relative contributions of the alpha-globin enhancers to gene expression.
    Blood. 2021;137:572-575.
    PubMed    


  34. DEANS AJ
    Fanconi anemia, put to sleep.
    Blood. 2021;137:286-288.
    PubMed    


  35. THOMAS M, Scully M
    How I Treat Microangiopathic Hemolytic Anemia in Patients with Cancer.
    Blood. 2021 Jan 21. pii: 475029. doi: 10.1182/blood.2019003810.
    PubMed     Abstract available


  36. CAZZOLA M
    Introduction to a How I Treat Series on Acquired Hemolytic Anemia.
    Blood. 2021 Jan 21. pii: 475027. doi: 10.1182/blood.2020009747.
    PubMed    


  37. BARCELLINI W, Fattizzo B
    How I treat warm autoimmune hemolytic anemia.
    Blood. 2021 Jan 21. pii: 475030. doi: 10.1182/blood.2019003808.
    PubMed     Abstract available


  38. PIRENNE F
    Heme control to major B (cell): are you listening?
    Blood. 2021;137:153-154.
    PubMed    


  39. PAL M, Bao W, Wang R, Liu Y, et al
    Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease.
    Blood. 2021;137:269-280.
    PubMed     Abstract available


  40. MU A, Hira A, Niwa A, Osawa M, et al
    Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
    Blood. 2021 Jan 12. pii: 474923. doi: 10.1182/blood.2020009111.
    PubMed     Abstract available


  41. SALIB C, Hussein S
    A case of hairy cell leukemia with markedly hypocellular marrow mimicking aplastic anemia.
    Blood. 2021;137:142.
    PubMed    


    December 2020
  42. SICA M, Pellecchia A, De Angioletti M, Caocci G, et al
    Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH.
    Blood. 2020;136:3082-3085.
    PubMed    


  43. MARIANI R, Liu H
    Severe transient pancytopenia with dyserythropoiesis and dysmegakaryopoiesis in COVID-19-associated MIS-C.
    Blood. 2020;136:2964.
    PubMed    


  44. ARORA S, Ganapathi KA
    Prominent pseudo-Gaucher cells in a patient with beta-thalassemia intermedia and plasma cell myeloma.
    Blood. 2020;136:2839.
    PubMed    


  45. PARROW NL, Violet PC, Ajit George N, Ali F, et al
    Dietary Iron Restriction Improves Markers of Disease Severity in Murine Sickle Cell Anemia.
    Blood. 2020 Dec 8. pii: 474426. doi: 10.1182/blood.2020006919.
    PubMed    


    November 2020
  46. ABKOWITZ JL
    A simple Rx for congenital erythropoietic porphyria.
    Blood. 2020;136:2371-2372.
    PubMed    


    October 2020
  47. DEWARRAT N, Blum S
    Heavy metal.
    Blood. 2020;136:1993.
    PubMed    


    September 2020
  48. ARJONA E, Huerta A, Goicoechea de Jorge E, Rodriguez de Cordoba S, et al
    Familial risk of developing atypical hemolytic-uremic syndrome.
    Blood. 2020;136:1558-1561.
    PubMed    


  49. KIM-SHAPIRO DB, Gladwin MT
    Arginine for mitochondrial oxidative enzymopathy.
    Blood. 2020;136:1376-1378.
    PubMed    


  50. MORRIS CR, Brown LAS, Reynolds M, Dampier CD, et al
    Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain.
    Blood. 2020;136:1402-1406.
    PubMed     Abstract available


  51. LUZZATTO L, Ally M, Notaro R
    Glucose-6-phosphate dehydrogenase deficiency.
    Blood. 2020;136:1225-1240.
    PubMed     Abstract available


  52. SCHELL B, Fenneteau O
    Brandalise syndrome: a rare inclusion cell disease.
    Blood. 2020;136:1373.
    PubMed    


  53. RISINGER M, Kalfa TA
    Red cell membrane disorders: structure meets function.
    Blood. 2020;136:1250-1261.
    PubMed     Abstract available


  54. CAZZOLA M
    Introduction to a review series on inherited anemias.
    Blood. 2020;136:1215-1216.
    PubMed    


  55. IOLASCON A, Andolfo I, Russo R
    Congenital dyserythropoietic anemias.
    Blood. 2020;136:1274-1283.
    PubMed     Abstract available


  56. GRACE RF, Barcellini W
    Management of pyruvate kinase deficiency in children and adults.
    Blood. 2020;136:1241-1249.
    PubMed     Abstract available


  57. BROUSSE V, Connes P
    Vasomotor hyperresponsiveness in SCD.
    Blood. 2020;136:1120-1121.
    PubMed    


  58. VELUSWAMY S, Shah P, Khaleel M, Thuptimdang W, et al
    Progressive vasoconstriction with sequential thermal stimulation indicates vascular dysautonomia in sickle cell disease.
    Blood. 2020;136:1191-1200.
    PubMed     Abstract available


    August 2020

  59. Kordasti S, Marsh J, Al-Khan S, et al. Functional characterization of CD4+ T cells in aplastic anemia. Blood. 2012;119(9):2033-2043.
    Blood. 2020;136:1114.
    PubMed    


  60. STEINBERG MH
    Fetal Hemoglobin in Sickle Cell Anemia.
    Blood. 2020 Aug 17. pii: 463324. doi: 10.1182/blood.2020007645.
    PubMed     Abstract available


  61. SCHEINBERG P
    Why do Tregs suddenly disappear in aplastic anemia?
    Blood. 2020;136:779-780.
    PubMed    


  62. BERZUINI A, Bianco C, Paccapelo C, Bertolini F, et al
    Red cell-bound antibodies and transfusion requirements in hospitalized patients with COVID-19.
    Blood. 2020;136:766-768.
    PubMed    


  63. VOIT RA, Grace RF
    Pyruvate kinase deficiency in a newborn with extramedullary hematopoiesis in the skin.
    Blood. 2020;136:770.
    PubMed    


    July 2020
  64. OKAMOTO Y, Abe M, Mu A, Tempaku Y, et al
    SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.
    Blood. 2020 Jul 31. pii: 461664. doi: 10.1182/blood.2019003782.
    PubMed     Abstract available


  65. CARLESSO N
    Targeting the bone marrow niche in hemoglobinopathies.
    Blood. 2020;136:529-531.
    PubMed    


  66. BRAZAUSKAS R, Scigliuolo GM, Wang HL, Cappelli B, et al
    Risk score to predict event-free survival after hematopoietic cell transplant for sickle cell disease.
    Blood. 2020;136:623-626.
    PubMed     Abstract available


  67. DA COSTA LM, Leblanc TM, Narla M
    Diamond-Blackfan Anemia.
    Blood. 2020 Jul 23. pii: 461552. doi: 10.1182/blood.2019000947.
    PubMed     Abstract available


  68. ROTH A
    Do temperature and time matter in cold agglutinin disease?
    Blood. 2020;136:380-381.
    PubMed    


  69. BERENTSEN S, Barcellini W, D'Sa S, Randen U, et al
    Cold agglutinin disease revisited: a multinational, observational study of 232 patients.
    Blood. 2020;136:480-488.
    PubMed     Abstract available


  70. BLOUIN JM, Ged C, Lalanne M, Lamrissi-Garcia I, et al
    Iron chelation rescues hemolytic anemia and skin photosensitivity in congenital erythropoietic porphyria.
    Blood. 2020 Jul 17. pii: 461423. doi: 10.1182/blood.2020006037.
    PubMed     Abstract available


  71. KATO GJ
    Sickle particulars of microparticles.
    Blood. 2020;136:154-155.
    PubMed    


  72. GARNIER Y, Ferdinand S, Garnier M, Cita KC, et al
    Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties.
    Blood. 2020;136:247-256.
    PubMed     Abstract available


  73. EVANS EL, Povstyan OV, De Vecchis D, Macrae F, et al
    RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis.
    Blood. 2020;136:140-144.
    PubMed    


    June 2020
  74. KHAN R, Menard M, Jen CC, Chen X, et al
    Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP.
    Blood. 2020;135:2420-2424.
    PubMed     Abstract available


  75. SHANDER A, Kaufman M, Goodnough LT
    How I treat Anemia in the Perisurgical Setting.
    Blood. 2020 Jun 18. pii: 461028. doi: 10.1182/blood.2019003945.
    PubMed     Abstract available


  76. FISHBANE S, Coyne DW
    How we treat Renal Anemia.
    Blood. 2020 Jun 18. pii: 461033. doi: 10.1182/blood.2019004330.
    PubMed     Abstract available


  77. GILREATH JA, Rodgers GM
    How I treat Cancer Anemia.
    Blood. 2020 Jun 18. pii: 461032. doi: 10.1182/blood.2019004017.
    PubMed     Abstract available


  78. DEWAELE K, Claeys R
    Hemophagocytic lymphohistiocytosis in SARS-CoV-2 infection.
    Blood. 2020;135:2323.
    PubMed    


  79. CAZZOLA M
    Introduction to a How I Treat Series on Anemia.
    Blood. 2020 Jun 18. pii: 461030. doi: 10.1182/blood.2020007025.
    PubMed    


  80. NICKEL RS, Margulies S, Frazer B, Luban NLC, et al
    Combination dose-escalated hydroxyurea and transfusion: an approach to conserve blood during the COVID-19 pandemic.
    Blood. 2020;135:2320-2322.
    PubMed    


  81. CHEN BY, Song J, Hu CL, Chen SB, et al
    SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
    Blood. 2020;135:2271-2285.
    PubMed     Abstract available


  82. CASU C, Pettinato M, Liu A, Aghajan M, et al
    Correcting beta-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
    Blood. 2020 Jun 17. pii: 461017. doi: 10.1182/blood.2019004719.
    PubMed     Abstract available


  83. HUANG P, Peslak SA, Lan X, Khandros E, et al
    The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression.
    Blood. 2020;135:2121-2132.
    PubMed     Abstract available


  84. WALTERS MC
    Sickle marrow: double, double toil and trouble.
    Blood. 2020;135:2017-2018.
    PubMed    


  85. PARK SY, Matte A, Jung Y, Ryu J, et al
    Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion.
    Blood. 2020;135:2071-2084.
    PubMed     Abstract available


    May 2020
  86. DEBAUN MR
    Initiating adjunct low-dose hydroxyurea therapy for stroke prevention in children with SCA during the COVID-19 pandemic.
    Blood. 2020;135:1997-1999.
    PubMed    


  87. KHANDROS E, Huang P, Peslak SA, Sharma M, et al
    Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
    Blood. 2020;135:1957-1968.
    PubMed     Abstract available


  88. PETZER V, Tymoszuk P, Asshoff M, Carvalho J, et al
    A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the Anemia of Chronic Disease.
    Blood. 2020 May 21. pii: 456038. doi: 10.1182/blood.2019004653.
    PubMed     Abstract available


  89. SUN L, Babushok DV
    Secondary myelodysplastic syndrome and leukemia in acquired aplastic anemia and paroxysmal nocturnal hemoglobinuria.
    Blood. 2020 May 19. pii: 456026. doi: 10.1182/blood.2019000940.
    PubMed     Abstract available


  90. GORDEUK VR
    Sickle cell vaso-occlusion: the clot thickens.
    Blood. 2020;135:1726-1727.
    PubMed    


  91. SPARKENBAUGH EM, Chen C, Brzoska T, Nguyen J, et al
    Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease.
    Blood. 2020;135:1783-1787.
    PubMed     Abstract available


  92. THOMES RM, Rosenstein LJ
    Pernicious anemia.
    Blood. 2020;135:1719.
    PubMed    


    April 2020
  93. SCHINDLER D, Kalb R
    Disease and mutation: correlations coming to fruition.
    Blood. 2020;135:1514-1515.
    PubMed    


  94. APRILE A, Gulino A, Storto M, Villa I, et al
    Hematopoietic stem cell function in beta-thalassemia is impaired and is rescued by targeting the bone marrow niche.
    Blood. 2020 Apr 28. pii: 454666. doi: 10.1182/blood.2019002721.
    PubMed     Abstract available


  95. LIM SP, Costantini B, Mian SA, Perez Abellan P, et al
    Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction.
    Blood. 2020 Apr 15. pii: 454391. doi: 10.1182/blood.2019001347.
    PubMed     Abstract available


  96. SVATON M, Skvarova Kramarzova K, Kanderova V, Mancikova A, et al
    A homozygous deletion in the SLC19A1 gene as a cause of folate-dependent recurrent megaloblastic anemia.
    Blood. 2020 Apr 10. pii: 454359. doi: 10.1182/blood.2019003178.
    PubMed    


  97. VAN ZEVENTER IA, de Graaf AO, Wouters HJCM, van der Reijden BA, et al
    Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals.
    Blood. 2020;135:1161-1170.
    PubMed     Abstract available


  98. STEENSMA DP
    Does clonal hematopoiesis explain unexplained anemia?
    Blood. 2020;135:1080-1082.
    PubMed    


  99. GHANNAM JY, Xu X, Maric I, Dillon L, et al
    Baseline TP53 mutations in adults with SCD developing myeloid malignancy following hematopoietic cell transplantation.
    Blood. 2020;135:1185-1188.
    PubMed    


    March 2020
  100. SARAF SL
    Heme A1M'ed at the kidney in sickle cell disease.
    Blood. 2020;135:979-981.
    PubMed    


  101. OFORI-ACQUAH SF, Hazra R, Orikogbo OO, Crosby D, et al
    Hemopexin deficiency promotes acute kidney injury in sickle cell disease.
    Blood. 2020;135:1044-1048.
    PubMed     Abstract available


  102. BRODSKY RA
    A complementary new drug for PNH.
    Blood. 2020;135:884-885.
    PubMed    


  103. ROTH A, Nishimura JI, Nagy Z, Gaal-Weisinger J, et al
    The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria.
    Blood. 2020;135:912-920.
    PubMed     Abstract available


    February 2020
  104. JUNG M, Ramanagoudr-Bhojappa R, van Twest S, Rosti RO, et al
    Association of clinical severity with FANCB variant type in Fanconi anemia.
    Blood. 2020 Feb 27. pii: 452579. doi: 10.1182/blood.2019003249.
    PubMed     Abstract available


  105. GANZ T
    Drugging erythroferrone to treat anemias.
    Blood. 2020;135:516-518.
    PubMed    


  106. AREZES J, Foy N, McHugh K, Quinkert D, et al
    Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia.
    Blood. 2020;135:547-557.
    PubMed     Abstract available


    January 2020
  107. PENA VN, Naik RP
    Paroxysmal cold hemoglobinuria: a unique constellation of peripheral smear findings.
    Blood. 2020;135:393.
    PubMed    


  108. ANAND I, Gupta P
    How I treat Anemia in Heart Failure.
    Blood. 2020 Jan 2. pii: 430052. doi: 10.1182/blood.2019004004.
    PubMed     Abstract available


    December 2019
  109. YANG G, Hanna CM
    Hematopoietic findings in a patient with scurvy.
    Blood. 2019;134:2330.
    PubMed    


  110. COOPER DM, Liem RI
    Translating exercise benefits in sickle cell disease.
    Blood. 2019;134:2227-2229.
    PubMed    


  111. MERLET AN, Messonnier LA, Coudy-Gandilhon C, Bechet D, et al
    Beneficial effects of endurance exercise training on skeletal muscle microvasculature in sickle cell disease patients.
    Blood. 2019;134:2233-2241.
    PubMed     Abstract available


  112. STENGER EO, Shenoy S, Krishnamurti L
    How I treat sickle cell disease with hematopoietic cell transplantation.
    Blood. 2019;134:2249-2260.
    PubMed     Abstract available


    November 2019
  113. SAHIN I, Niroula R
    Erythrophagocytosis on bone marrow found in severe autoimmune hemolytic anemia with reticulocytopenia.
    Blood. 2019;134:1877.
    PubMed    


  114. CUNNINGHAM-RUNDLES C
    Common variable immune deficiency: case studies.
    Blood. 2019;134:1787-1795.
    PubMed     Abstract available


  115. CHEN JJ, Zhang S
    Heme-regulated eIF2alpha kinase in erythropoiesis and hemoglobinopathies.
    Blood. 2019;134:1697-1707.
    PubMed     Abstract available


  116. MIANO M, Eikema DJ, de la Fuente J, Bosman P, et al
    Stem Cell Transplantation for Diamond-Blackfan Anemia. a Retrospective Study on Behalf of Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (EBMT).
    Blood. 2019;134.
    PubMed     Abstract available


  117. LING T, Birger Y, Stankiewicz MJ, Ben-Haim N, et al
    Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis.
    Blood. 2019;134:1619-1631.
    PubMed     Abstract available


    October 2019
  118. VINANICA N, Yong A, Wong D, Png YT, et al
    Specific stimulation of T lymphocytes with erythropoietin for adoptive immunotherapy.
    Blood. 2019 Oct 31. pii: 422689. doi: 10.1182/blood.2019001645.
    PubMed     Abstract available


  119. XAVIER-FERRUCIO J, Scanlon V, Li X, Zhang PX, et al
    Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.
    Blood. 2019;134:1547-1557.
    PubMed     Abstract available


  120. HUA P, Roy NB, de la Fuente J, Wang G, et al
    Single cell analysis of bone marrow derived CD34+ cells from children with sickle cell disease and thalassemia.
    Blood. 2019 Oct 16. pii: 387151. doi: 10.1182/blood.2019002301.
    PubMed    


  121. MAGRIN E, Miccio A, Cavazzana M
    Lentiviral and genome-editing strategies for the treatment of beta-hemoglobinopathies.
    Blood. 2019;134:1203-1213.
    PubMed     Abstract available


  122. CUTTS A, Vavoulis DV, Petrou M, Smith F, et al
    A method for noninvasive prenatal diagnosis of monogenic autosomal recessive disorders.
    Blood. 2019;134:1190-1193.
    PubMed    


    August 2019
  123. LIU Y, Zhong H, Bao W, Mendelson A, et al
    Patrolling monocytes scavenge endothelial-adherent sickle RBCs: a novel mechanism of inhibition of vaso-occlusion in SCD.
    Blood. 2019;134:579-590.
    PubMed     Abstract available


  124. CAMASCHELLA C
    GDF11 is not the target of luspatercept.
    Blood. 2019;134:500-501.
    PubMed    


    July 2019
  125. KAGEYAMA Y, Miwa H, Tawara I, Ohishi K, et al
    A population of CD20(+)CD27(+)CD43(+)CD38(lo/int) B1 cells in PNH are missing GPI-anchored proteins and harbor PIGA mutations.
    Blood. 2019;134:89-92.
    PubMed    


  126. HADJADJ J, Aladjidi N, Fernandes H, Leverger G, et al
    Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes.
    Blood. 2019;134:9-21.
    PubMed     Abstract available


    June 2019
  127. BABUSHOK DV
    Eltrombopag: wielding a double-edged sword?
    Blood. 2019;133:2555-2556.
    PubMed    


  128. KATO GJ
    Sickle cells and sickle trait in thrombosis.
    Blood. 2019;133:2463.
    PubMed    


  129. SHIN TH, Baek EJ, Corat MAF, Chen S, et al
    CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs.
    Blood. 2019;133:2542-2545.
    PubMed    


  130. FAES C, Ilich A, Sotiaux A, Sparkenbaugh EM, et al
    Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease.
    Blood. 2019;133:2529-2541.
    PubMed     Abstract available


    May 2019
  131. WOOD JC
    Brain O2 reserve in sickle cell disease.
    Blood. 2019;133:2356-2358.
    PubMed    


  132. LE CQ, Myers G, Habara A, Jearawiriyapaisarn N, et al
    Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis.
    Blood. 2019;133:2455-2459.
    PubMed    


  133. TOWNES TM
    A novel therapeutic strategy for beta-thalassemia.
    Blood. 2019;133:2245-2246.
    PubMed    


  134. XU S, Luk K, Yao Q, Shen AH, et al
    Editing aberrant splice sites efficiently restores beta-globin expression in beta-thalassemia.
    Blood. 2019;133:2255-2262.
    PubMed     Abstract available


  135. WARE RE, Thornburg CD
    Your tired, your poor, your huddled masses.
    Blood. 2019;133:2010-2011.
    PubMed    


  136. DE FRANCESCHI L, Lux C, Piel FB, Gianesin B, et al
    Access to emergency departments for acute events and identification of sickle cell disease in refugees.
    Blood. 2019;133:2100-2103.
    PubMed    


  137. SADLER KE, Stucky CL
    Blocking COX-2 for sickle cell pain relief.
    Blood. 2019;133:1924-1925.
    PubMed    


  138. KHASABOVA IA, Uhelski M, Khasabov SG, Gupta K, et al
    Sensitization of nociceptors by prostaglandin E2-glycerol contributes to hyperalgesia in mice with sickle cell disease.
    Blood. 2019;133:1989-1998.
    PubMed     Abstract available


    April 2019
  139. STEINBERG MH
    Primary polymerization prevention.
    Blood. 2019;133:1797-1798.
    PubMed    


  140. HOWARD J, Hemmaway CJ, Telfer P, Layton DM, et al
    A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease.
    Blood. 2019;133:1865-1875.
    PubMed     Abstract available


    March 2019
  141. MARKS EI, Ollila TA
    Acanthocytosis causing chronic hemolysis in a patient with advanced cirrhosis.
    Blood. 2019;133:1518.
    PubMed    


  142. PIGA A, Perrotta S, Gamberini MR, Voskaridou E, et al
    Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with beta-thalassemia.
    Blood. 2019;133:1279-1289.
    PubMed     Abstract available


  143. KENNEDY AL, Shimamura A
    Genetic predisposition to MDS: clinical features and clonal evolution.
    Blood. 2019;133:1071-1085.
    PubMed     Abstract available


  144. TANAKA TN, Bejar R
    MDS overlap disorders and diagnostic boundaries.
    Blood. 2019;133:1086-1095.
    PubMed     Abstract available


    February 2019
  145. BERENTSEN S
    Cold agglutinins: fending off the attack.
    Blood. 2019;133:885-886.
    PubMed    


  146. MARTYN GE, Wienert B, Kurita R, Nakamura Y, et al
    A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site.
    Blood. 2019;133:852-856.
    PubMed     Abstract available


  147. THAKAR MS, Broglie L, Logan B, Artz A, et al
    The Hematopoietic Cell Transplant Comorbidity Index predicts survival after allogeneic transplant for nonmalignant diseases.
    Blood. 2019;133:754-762.
    PubMed     Abstract available


  148. CONNELL NT
    Ravulizumab: a complementary option for PNH.
    Blood. 2019;133:503-504.
    PubMed    


  149. DEBAUN MR, Ghafuri DL, Rodeghier M, Maitra P, et al
    Decreased median survival of adults with sickle cell disease after adjusting for left truncation bias: a pooled analysis.
    Blood. 2019;133:615-617.
    PubMed    


  150. LEE JW, Sicre de Fontbrune F, Wong Lee Lee L, Pessoa V, et al
    Ravulizumab (ALXN1210) vs eculizumab in adult patients with PNH naive to complement inhibitors: the 301 study.
    Blood. 2019;133:530-539.
    PubMed     Abstract available


  151. KULASEKARARAJ AG, Hill A, Rottinghaus ST, Langemeijer S, et al
    Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor-experienced adult patients with PNH: the 302 study.
    Blood. 2019;133:540-549.
    PubMed     Abstract available


    January 2019
  152. DOTY RT, Yan X, Lausted C, Munday AD, et al
    Single-cell analyses demonstrate that a heme-GATA1 feedback loop regulates red cell differentiation.
    Blood. 2019;133:457-469.
    PubMed     Abstract available


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