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Articles published in Blood

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Single Articles


    July 2022
  1. PINCEZ T, Aladjidi N, Heritier S, Garnier N, et al
    Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias.
    Blood. 2022;140:253-261.
    PubMed     Abstract available


  2. NISS O, Detterich JA, Wood JC, Coates TD, et al
    Early initiation of disease-modifying therapy can impede or prevent diffuse myocardial fibrosis in sickle cell anemia.
    Blood. 2022 Jul 20. pii: 485971. doi: 10.1182/blood.2021015303.
    PubMed    


  3. MCREYNOLDS LJ, Rafati M, Wang Y, Ballew BJ, et al
    Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes.
    Blood. 2022 Jul 1. pii: 485762. doi: 10.1182/blood.2022016508.
    PubMed     Abstract available


    June 2022
  4. LANZKRON S, Pecker L
    Pain without gain: steroids and sickle crisis.
    Blood. 2022;139:3678-3679.
    PubMed    


  5. THAKRAL B, Bueso-Ramos CE
    Unexpected presentation of cold agglutinin syndrome with B-acute lymphoblastic leukemia.
    Blood. 2022;139:3778.
    PubMed    


  6. WALTER O, Cougoul P, Maquet J, Bartolucci P, et al
    Risk of vaso-occlusive episode after exposure to corticosteroids in patients with sickle cell disease.
    Blood. 2022;139:3771-3777.
    PubMed     Abstract available


  7. KROLL MH, Rojas-Hernandez C, Yee C
    Hematologic complications of immune checkpoint inhibitors.
    Blood. 2022;139:3594-3604.
    PubMed     Abstract available


  8. GAVRIILAKI E, de Latour RP, Risitano AM
    Advancing therapeutic complement inhibition in hematologic diseases: PNH and beyond.
    Blood. 2022;139:3571-3582.
    PubMed     Abstract available


  9. GERBER GF, Brodsky RA
    Pegcetacoplan for paroxysmal nocturnal hemoglobinuria.
    Blood. 2022;139:3361-3365.
    PubMed     Abstract available


  10. DOTY RT, Fan X, Young DJ, Liang J, et al
    Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis.
    Blood. 2022;139:3439-3449.
    PubMed     Abstract available


    May 2022
  11. ISKANDER D, Warren AJ
    Turning up the HEAT(R3) in Diamond-Blackfan anemia.
    Blood. 2022;139:3101-3102.
    PubMed    


  12. BODINE DM
    Anemia of inflammation is all the RAGE.
    Blood. 2022;139:3106-3107.
    PubMed    


  13. XU JZ, Thein SL
    Revisiting anemia in sickle cell disease and finding the balance with therapeutic approaches.
    Blood. 2022;139:3030-3039.
    PubMed     Abstract available


    April 2022
  14. NOVELLI EM
    Extinguishing the fire in sickle cell anemia.
    Blood. 2022;139:2578-2580.
    PubMed    


  15. DAS NK, Jain C, Sankar A, Schwartz AJ, et al
    Modulation of the HIF2alpha-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis.
    Blood. 2022;139:2547-2552.
    PubMed     Abstract available


  16. WHITE NJ
    What causes malaria anemia?
    Blood. 2022;139:2268-2269.
    PubMed    


  17. MAHAMAR A, Gonzales Hurtado PA, Morrison R, Boone R, et al
    Plasma biomarkers of hemoglobin loss in Plasmodium falciparum-infected children identified by quantitative proteomics.
    Blood. 2022;139:2361-2376.
    PubMed     Abstract available


  18. NWOGBO OV, Loghavi S
    Essential thrombocythemia complicating hemoglobin SC disease and presenting with priapism.
    Blood. 2022;139:2258.
    PubMed    


  19. WANG M, Dingler FA, Patel KJ
    Genotoxic aldehydes in the hematopoietic system.
    Blood. 2022;139:2119-2129.
    PubMed     Abstract available


  20. TOPFER SK, Feng R, Huang P, Ly LC, et al
    Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
    Blood. 2022;139:2107-2118.
    PubMed     Abstract available


    March 2022
  21. CAZZOLA M
    RNA missplicing and ring sideroblasts in MDS.
    Blood. 2022;139:1933-1935.
    PubMed    


  22. WOOD JC
    Pulmonary hypertension in thalassemia: a call to action.
    Blood. 2022;139:1937-1938.
    PubMed    


  23. PINTO VM, Musallam KM, Derchi G, Graziadei G, et al
    Mortality in beta-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization.
    Blood. 2022;139:2080-2083.
    PubMed    


  24. SCHMIDT CQ, Schrezenmeier H, Kavanagh D
    Complement and the prothrombotic state.
    Blood. 2022;139:1954-1972.
    PubMed     Abstract available


  25. DOSUNMU-OGUNBI A, Yuan S, Reynolds M, Giordano L, et al
    SOD2 V16A amplifies vascular dysfunction in sickle cell patients by curtailing mitochondria complex IV activity.
    Blood. 2022;139:1760-1765.
    PubMed     Abstract available


  26. MESSONNIER LA
    Mitochondrial function in sickle cell disease.
    Blood. 2022;139:1616-1617.
    PubMed    


  27. WONTAKAL SN, Britto M, Zhang H, Han Y, et al
    RACGAP1 variants in a sporadic case of CDA III implicate the dysfunction of centralspindlin as the basis of the disease.
    Blood. 2022;139:1413-1418.
    PubMed    


    February 2022
  28. REES DC, Kilinc Y, Unal S, Dampier CD, et al
    A randomized, placebo-controlled, double-blind trial of canakinumab in children and young adults with sickle cell anemia.
    Blood. 2022 Feb 28. pii: 484189. doi: 10.1182/blood.2021013674.
    PubMed     Abstract available


  29. O'DONOHUE MF, Da Costa LM, Lezzerini M, Unal S, et al
    HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia.
    Blood. 2022 Feb 25. pii: 484180. doi: 10.1182/blood.2021011846.
    PubMed     Abstract available


  30. GALLAGHER PG
    Anemia in the pediatric patient.
    Blood. 2022 Feb 25. pii: 484178. doi: 10.1182/blood.2020006479.
    PubMed     Abstract available


  31. MENON AV, Liu J, Tsai HP, Zeng L, et al
    Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease.
    Blood. 2022;139:936-941.
    PubMed     Abstract available


    January 2022
  32. NEUMANN NM, Wen KW
    Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts, thrombocytosis, and mutated JAK2/SF3B1 without anemia.
    Blood. 2022;139:466.
    PubMed    


  33. RAO VK
    Evans syndrome: pathology and genomic hubris.
    Blood. 2022;139:312-313.
    PubMed    


  34. KUMAR D, Prince C, Bennett CM, Briones M, et al
    T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome.
    Blood. 2022;139:369-383.
    PubMed     Abstract available


  35. DULMOVITS BM, Tang Y, Papoin J, He M, et al
    HMGB1-Mediated Restriction of EPO Signaling Contributes to Anemia of Inflammation.
    Blood. 2022 Jan 18. pii: 483547. doi: 10.1182/blood.2021012048.
    PubMed     Abstract available


  36. LUDWIG L, Lareau CA, Bao EL, Liu N, et al
    A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1.
    Blood. 2022 Jan 14. pii: 483530. doi: 10.1182/blood.2021013753.
    PubMed     Abstract available


  37. DHUNPUTH C, Ducassou S, Fernandes H, Picard C, et al
    Abatacept is useful in autoimmune cytopenia with immunopathologic manifestations caused by CTLA-4 defects.
    Blood. 2022;139:300-304.
    PubMed    


    December 2021
  38. PAGLIUCA S, Gurnari C, Awada H, Kishtagari A, et al
    The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders.
    Blood. 2021;138:2781-2798.
    PubMed     Abstract available


  39. TANG A, Strat AN, Rahman M, Zhang H, et al
    Murine bone marrow mesenchymal stromal cells have reduced hematopoietic maintenance ability in sickle cell disease.
    Blood. 2021;138:2570-2582.
    PubMed     Abstract available


  40. PECKER L, Hussain S, Mahesh J, Varadhan R, et al
    Diminished ovarian reserve in young women with sickle cell anemia.
    Blood. 2021 Dec 5. pii: 482897. doi: 10.1182/blood.2021012756.
    PubMed    


  41. MARTIN MERINERO H, Zhang Y, Arjona E, Del Angel G, et al
    Functional characterization of 105 factor H variants associated with aHUS: lessons for variant classification.
    Blood. 2021;138:2185-2201.
    PubMed     Abstract available


    November 2021
  42. DUCHEMANN B, Lazarian G
    Post-SARS-CoV-2 vaccination acute hemolysis in an older man: don't forget to look at the blood smear.
    Blood. 2021;138:2153.
    PubMed    


  43. PINCEZ T, Lee SSK, Ilboudo Y, Preuss M, et al
    Clonal hematopoiesis in sickle cell disease.
    Blood. 2021;138:2148-2152.
    PubMed    


  44. LUZZATTO L
    Control of hemolysis in patients with PNH.
    Blood. 2021;138:1908-1910.
    PubMed    


  45. KULASEKARARAJ AG, Risitano AM, Maciejewski JP, Notaro R, et al
    Phase 2 study of danicopan in patients with paroxysmal nocturnal hemoglobinuria with an inadequate response to eculizumab.
    Blood. 2021;138:1928-1938.
    PubMed     Abstract available


  46. EL SISSY C, Saldman A, Zanetta G, Martins PV, et al
    COVID-19 as a potential trigger of complement-mediated atypical HUS.
    Blood. 2021;138:1777-1782.
    PubMed    


  47. FENG Y, Feng W
    Numerous ring sideroblasts in chronic neutrophilic leukemia.
    Blood. 2021;138:1783.
    PubMed    


  48. ZAIMOKU Y, Patel BA, Adams SD, Shalhoub RN, et al
    HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia.
    Blood. 2021 Nov 1. pii: 477734. doi: 10.1182/blood.2021012895.
    PubMed     Abstract available


    September 2021
  49. HENRY ER, Metaferia B, Li Q, Harper J, et al
    Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
    Blood. 2021;138:1172-1181.
    PubMed     Abstract available


  50. LIU Y, Pal M, Bao W, Shi PA, et al
    Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease.
    Blood. 2021;138:1162-1171.
    PubMed     Abstract available


  51. IRELAND RM, Rees DC
    Two brothers with a novel KLF1 mutation.
    Blood. 2021;138:1087.
    PubMed    


  52. ABRAHAM AA, Tisdale JF
    Gene therapy for sickle cell disease: moving from the bench to the bedside.
    Blood. 2021;138:932-941.
    PubMed     Abstract available


  53. BOLLARD CM
    Introduction to a review series on gene therapy and gene editing for sickle cell disease and hemophilia.
    Blood. 2021;138:913.
    PubMed    


  54. PATEL BA, Groarke EM, Lotter J, Shalhoub RN, et al
    Long-term outcomes in severe aplastic anemia patients treated with immunosuppression and eltrombopag: a phase 2 study.
    Blood. 2021 Sep 15. pii: 476916. doi: 10.1182/blood.2021012130.
    PubMed     Abstract available


    August 2021
  55. COCHRAN T, Li W
    Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation.
    Blood. 2021;138:738.
    PubMed    


  56. XU Z, Mueller R
    Myelodysplastic pure red cell aplasia.
    Blood. 2021;138:500.
    PubMed    


    July 2021
  57. JALINK M, Berentsen S, Castillo J, Treon SPP, et al
    Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome.
    Blood. 2021 Jul 22. pii: 476451. doi: 10.1182/blood.2021012039.
    PubMed    


  58. RICE L, Schwartz MR
    Sickle cell hepatopathy with spur cell anemia.
    Blood. 2021;138:283.
    PubMed    


  59. GERBER GF, Yuan X, Yu J, Cher BAY, et al
    COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:3670-3673.
    PubMed    


    June 2021
  60. MORENO C
    Autoimmune cytopenia and CLL ride together.
    Blood. 2021;137:3464-3465.
    PubMed    


  61. MARTIN MERINERO H, Subias M, Pereda A, Gomez-Rubio E, et al
    Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases.
    Blood. 2021;137:3484-3494.
    PubMed     Abstract available


  62. REJESKI K, Perez Perez A, Sesques P, Hoster E, et al
    CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma.
    Blood. 2021 Jun 24. pii: 476241. doi: 10.1182/blood.2020010543.
    PubMed     Abstract available


  63. PSATHA N, Georgakopoulou A, Li C, Nandakumar V, et al
    Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo.
    Blood. 2021 Jun 4. pii: 476068. doi: 10.1182/blood.2020010020.
    PubMed     Abstract available


  64. RARICK KR, Pritchard KA
    The sickle erythrocyte yields another DAMP.
    Blood. 2021;137:3010-3011.
    PubMed    


  65. JONES RJ, DeBaun MR
    Leukemia after gene therapy for sickle cell disease: insertional mutagenesis, busulfan, both or neither.
    Blood. 2021 Jun 3. pii: 476065. doi: 10.1182/blood.2021011488.
    PubMed     Abstract available


  66. TUMBURU L, Ghosh-Choudhary S, Seifuddin FT, Barbu EA, et al
    Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease.
    Blood. 2021;137:3116-3126.
    PubMed     Abstract available


    May 2021
  67. RAB MAE, Bos J, van Oirschot BA, van Straaten S, et al
    Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy.
    Blood. 2021;137:2997-3001.
    PubMed    


  68. MANWANI D
    P-selectin and sickle cell disease: a balancing act.
    Blood. 2021;137:2573-2574.
    PubMed    


  69. VATS R, Kaminski TW, Ju EM, Brozska T, et al
    P-selectin deficiency promotes liver senescence in sickle cell disease mice.
    Blood. 2021;137:2676-2680.
    PubMed     Abstract available


  70. BRODSKY RA
    Eculizumab and aHUS: to stop or not.
    Blood. 2021;137:2419-2420.
    PubMed    


  71. FAKHOURI F, Fila M, Hummel A, Ribes D, et al
    Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study.
    Blood. 2021;137:2438-2449.
    PubMed     Abstract available


    April 2021
  72. CERCAMONDI CI, Stoffel N, Moretti D, Zoller T, et al
    Iron homeostasis during anemia of inflammation: a prospective study in patients with tuberculosis.
    Blood. 2021 Apr 19. pii: 475787. doi: 10.1182/blood.2020010562.
    PubMed     Abstract available


  73. SHAH N
    ELIPSIS: developing tools to better understand VOC in SCD.
    Blood. 2021;137:1987-1988.
    PubMed    


  74. GURNARI C, Maciejewski JP
    How I manage acquired pure red cell aplasia in adults.
    Blood. 2021;137:2001-2009.
    PubMed     Abstract available


  75. PITTMAN DD, Hines PC, Beidler D, Rybin D, et al
    Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers.
    Blood. 2021;137:2010-2020.
    PubMed     Abstract available


  76. TURNIS ME, Kaminska E, Smith KH, Kartchner BJ, et al
    Requirement for antiapoptotic MCL-1 during early erythropoiesis.
    Blood. 2021;137:1945-1958.
    PubMed     Abstract available


    March 2021
  77. GONG Y, Zhang X, Zhang Q, Zhang Y, et al
    A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the gamma-globin gene in beta-thalassemia.
    Blood. 2021;137:1652-1657.
    PubMed     Abstract available


  78. ZHU C, Lian Y, Wang C, Wu P, et al
    Single-cell transcriptomics dissects hematopoietic cell destruction and T cell engagement in aplastic anemia.
    Blood. 2021 Mar 24. pii: 475591. doi: 10.1182/blood.2020008966.
    PubMed     Abstract available


  79. HOSOKAWA K, Mizumaki H, Yoroidaka T, Maruyama H, et al
    HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia.
    Blood. 2021 Mar 22. pii: 475586. doi: 10.1182/blood.2020010586.
    PubMed    


  80. BRUGNARA C
    Less (Fe) is more (Hb) in SCA.
    Blood. 2021;137:1446-1447.
    PubMed    


  81. ANSARI J, Senchenkova EY, Vital SA, Al-Yafeai Z, et al
    Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease.
    Blood. 2021;137:1538-1549.
    PubMed     Abstract available


  82. ELDAR D, Ganzel C
    Erythrophagocytosis in a young adult with mycoplasma pneumonia-induced paroxysmal cold hemoglobinuria.
    Blood. 2021;137:1432.
    PubMed    


  83. BERENTSEN S
    How I treat cold agglutinin disease.
    Blood. 2021;137:1295-1303.
    PubMed     Abstract available


  84. BRODSKY RA
    How I treat paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:1304-1309.
    PubMed     Abstract available


  85. ZHABYEYEV P, Oudit GY
    Sickle cell disease, interleukin-18, and arrhythmias.
    Blood. 2021;137:1138-1139.
    PubMed    


  86. GUPTA A, Fei YD, Kim TY, Xie A, et al
    IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.
    Blood. 2021;137:1208-1218.
    PubMed     Abstract available


    February 2021
  87. WACHTER F, Archer NM
    Autoimmune hemolytic anemia complicated by parvovirus infection.
    Blood. 2021;137:1130.
    PubMed    


  88. GU Y, Yang R, Yang Y, Zhao Y, et al
    IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.
    Blood. 2021;137:945-958.
    PubMed     Abstract available


  89. AL-SAMKARI H
    Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
    Blood. 2021;137:888-895.
    PubMed     Abstract available


  90. WARE RE, Dertinger SD
    There's safety in numbers.
    Blood. 2021;137:729-731.
    PubMed    


  91. REES DC
    Hydroxyurea: coming to conclusions on safety.
    Blood. 2021;137:728-729.
    PubMed    


  92. GILLE AS, Pondarre C, Dalle JH, Bernaudin F, et al
    Hydroxyurea does not affect the spermatogonial pool in prepubertal patients with sickle cell disease.
    Blood. 2021;137:856-859.
    PubMed    


  93. JOSEPH L, Jean C, Manceau S, Chalas C, et al
    Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
    Blood. 2021;137:826-829.
    PubMed     Abstract available


  94. SHENG Y, Ma R, Yu C, Wu Q, et al
    Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
    Blood. 2021;137:610-623.
    PubMed     Abstract available


    January 2021
  95. BADAT M, Davies JOJ, Fisher CA, Downes DJ, et al
    A remarkable case of HbH disease illustrates the relative contributions of the alpha-globin enhancers to gene expression.
    Blood. 2021;137:572-575.
    PubMed    


  96. DEANS AJ
    Fanconi anemia, put to sleep.
    Blood. 2021;137:286-288.
    PubMed    


  97. THOMAS M, Scully M
    How I Treat Microangiopathic Hemolytic Anemia in Patients with Cancer.
    Blood. 2021 Jan 21. pii: 475029. doi: 10.1182/blood.2019003810.
    PubMed     Abstract available


  98. CAZZOLA M
    Introduction to a How I Treat Series on Acquired Hemolytic Anemia.
    Blood. 2021 Jan 21. pii: 475027. doi: 10.1182/blood.2020009747.
    PubMed    


  99. BARCELLINI W, Fattizzo B
    How I treat warm autoimmune hemolytic anemia.
    Blood. 2021 Jan 21. pii: 475030. doi: 10.1182/blood.2019003808.
    PubMed     Abstract available


  100. PIRENNE F
    Heme control to major B (cell): are you listening?
    Blood. 2021;137:153-154.
    PubMed    


  101. PAL M, Bao W, Wang R, Liu Y, et al
    Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease.
    Blood. 2021;137:269-280.
    PubMed     Abstract available


  102. MU A, Hira A, Niwa A, Osawa M, et al
    Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
    Blood. 2021 Jan 12. pii: 474923. doi: 10.1182/blood.2020009111.
    PubMed     Abstract available


  103. SALIB C, Hussein S
    A case of hairy cell leukemia with markedly hypocellular marrow mimicking aplastic anemia.
    Blood. 2021;137:142.
    PubMed    


    December 2020
  104. SICA M, Pellecchia A, De Angioletti M, Caocci G, et al
    Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH.
    Blood. 2020;136:3082-3085.
    PubMed    


  105. MARIANI R, Liu H
    Severe transient pancytopenia with dyserythropoiesis and dysmegakaryopoiesis in COVID-19-associated MIS-C.
    Blood. 2020;136:2964.
    PubMed    


  106. ARORA S, Ganapathi KA
    Prominent pseudo-Gaucher cells in a patient with beta-thalassemia intermedia and plasma cell myeloma.
    Blood. 2020;136:2839.
    PubMed    


  107. PARROW NL, Violet PC, Ajit George N, Ali F, et al
    Dietary Iron Restriction Improves Markers of Disease Severity in Murine Sickle Cell Anemia.
    Blood. 2020 Dec 8. pii: 474426. doi: 10.1182/blood.2020006919.
    PubMed    


    November 2020
  108. ABKOWITZ JL
    A simple Rx for congenital erythropoietic porphyria.
    Blood. 2020;136:2371-2372.
    PubMed    


    October 2020
  109. DEWARRAT N, Blum S
    Heavy metal.
    Blood. 2020;136:1993.
    PubMed    


    September 2020
  110. ARJONA E, Huerta A, Goicoechea de Jorge E, Rodriguez de Cordoba S, et al
    Familial risk of developing atypical hemolytic-uremic syndrome.
    Blood. 2020;136:1558-1561.
    PubMed    


  111. KIM-SHAPIRO DB, Gladwin MT
    Arginine for mitochondrial oxidative enzymopathy.
    Blood. 2020;136:1376-1378.
    PubMed    


  112. MORRIS CR, Brown LAS, Reynolds M, Dampier CD, et al
    Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain.
    Blood. 2020;136:1402-1406.
    PubMed     Abstract available


  113. LUZZATTO L, Ally M, Notaro R
    Glucose-6-phosphate dehydrogenase deficiency.
    Blood. 2020;136:1225-1240.
    PubMed     Abstract available


  114. SCHELL B, Fenneteau O
    Brandalise syndrome: a rare inclusion cell disease.
    Blood. 2020;136:1373.
    PubMed    


  115. RISINGER M, Kalfa TA
    Red cell membrane disorders: structure meets function.
    Blood. 2020;136:1250-1261.
    PubMed     Abstract available


  116. CAZZOLA M
    Introduction to a review series on inherited anemias.
    Blood. 2020;136:1215-1216.
    PubMed    


  117. IOLASCON A, Andolfo I, Russo R
    Congenital dyserythropoietic anemias.
    Blood. 2020;136:1274-1283.
    PubMed     Abstract available


  118. GRACE RF, Barcellini W
    Management of pyruvate kinase deficiency in children and adults.
    Blood. 2020;136:1241-1249.
    PubMed     Abstract available


  119. BROUSSE V, Connes P
    Vasomotor hyperresponsiveness in SCD.
    Blood. 2020;136:1120-1121.
    PubMed    


  120. VELUSWAMY S, Shah P, Khaleel M, Thuptimdang W, et al
    Progressive vasoconstriction with sequential thermal stimulation indicates vascular dysautonomia in sickle cell disease.
    Blood. 2020;136:1191-1200.
    PubMed     Abstract available


    August 2020

  121. Kordasti S, Marsh J, Al-Khan S, et al. Functional characterization of CD4+ T cells in aplastic anemia. Blood. 2012;119(9):2033-2043.
    Blood. 2020;136:1114.
    PubMed    


  122. STEINBERG MH
    Fetal Hemoglobin in Sickle Cell Anemia.
    Blood. 2020 Aug 17. pii: 463324. doi: 10.1182/blood.2020007645.
    PubMed     Abstract available


  123. SCHEINBERG P
    Why do Tregs suddenly disappear in aplastic anemia?
    Blood. 2020;136:779-780.
    PubMed    


  124. BERZUINI A, Bianco C, Paccapelo C, Bertolini F, et al
    Red cell-bound antibodies and transfusion requirements in hospitalized patients with COVID-19.
    Blood. 2020;136:766-768.
    PubMed    


  125. VOIT RA, Grace RF
    Pyruvate kinase deficiency in a newborn with extramedullary hematopoiesis in the skin.
    Blood. 2020;136:770.
    PubMed    


    July 2020
  126. OKAMOTO Y, Abe M, Mu A, Tempaku Y, et al
    SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.
    Blood. 2020 Jul 31. pii: 461664. doi: 10.1182/blood.2019003782.
    PubMed     Abstract available


  127. CARLESSO N
    Targeting the bone marrow niche in hemoglobinopathies.
    Blood. 2020;136:529-531.
    PubMed    


  128. BRAZAUSKAS R, Scigliuolo GM, Wang HL, Cappelli B, et al
    Risk score to predict event-free survival after hematopoietic cell transplant for sickle cell disease.
    Blood. 2020;136:623-626.
    PubMed     Abstract available


  129. DA COSTA LM, Leblanc TM, Narla M
    Diamond-Blackfan Anemia.
    Blood. 2020 Jul 23. pii: 461552. doi: 10.1182/blood.2019000947.
    PubMed     Abstract available


  130. ROTH A
    Do temperature and time matter in cold agglutinin disease?
    Blood. 2020;136:380-381.
    PubMed    


  131. BERENTSEN S, Barcellini W, D'Sa S, Randen U, et al
    Cold agglutinin disease revisited: a multinational, observational study of 232 patients.
    Blood. 2020;136:480-488.
    PubMed     Abstract available


  132. BLOUIN JM, Ged C, Lalanne M, Lamrissi-Garcia I, et al
    Iron chelation rescues hemolytic anemia and skin photosensitivity in congenital erythropoietic porphyria.
    Blood. 2020 Jul 17. pii: 461423. doi: 10.1182/blood.2020006037.
    PubMed     Abstract available


  133. KATO GJ
    Sickle particulars of microparticles.
    Blood. 2020;136:154-155.
    PubMed    


  134. GARNIER Y, Ferdinand S, Garnier M, Cita KC, et al
    Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties.
    Blood. 2020;136:247-256.
    PubMed     Abstract available


  135. EVANS EL, Povstyan OV, De Vecchis D, Macrae F, et al
    RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis.
    Blood. 2020;136:140-144.
    PubMed    


    June 2020
  136. KHAN R, Menard M, Jen CC, Chen X, et al
    Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP.
    Blood. 2020;135:2420-2424.
    PubMed     Abstract available


  137. SHANDER A, Kaufman M, Goodnough LT
    How I treat Anemia in the Perisurgical Setting.
    Blood. 2020 Jun 18. pii: 461028. doi: 10.1182/blood.2019003945.
    PubMed     Abstract available


  138. FISHBANE S, Coyne DW
    How we treat Renal Anemia.
    Blood. 2020 Jun 18. pii: 461033. doi: 10.1182/blood.2019004330.
    PubMed     Abstract available


  139. GILREATH JA, Rodgers GM
    How I treat Cancer Anemia.
    Blood. 2020 Jun 18. pii: 461032. doi: 10.1182/blood.2019004017.
    PubMed     Abstract available


  140. DEWAELE K, Claeys R
    Hemophagocytic lymphohistiocytosis in SARS-CoV-2 infection.
    Blood. 2020;135:2323.
    PubMed    


  141. CAZZOLA M
    Introduction to a How I Treat Series on Anemia.
    Blood. 2020 Jun 18. pii: 461030. doi: 10.1182/blood.2020007025.
    PubMed    


  142. NICKEL RS, Margulies S, Frazer B, Luban NLC, et al
    Combination dose-escalated hydroxyurea and transfusion: an approach to conserve blood during the COVID-19 pandemic.
    Blood. 2020;135:2320-2322.
    PubMed    


  143. CHEN BY, Song J, Hu CL, Chen SB, et al
    SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
    Blood. 2020;135:2271-2285.
    PubMed     Abstract available


  144. CASU C, Pettinato M, Liu A, Aghajan M, et al
    Correcting beta-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
    Blood. 2020 Jun 17. pii: 461017. doi: 10.1182/blood.2019004719.
    PubMed     Abstract available


  145. HUANG P, Peslak SA, Lan X, Khandros E, et al
    The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression.
    Blood. 2020;135:2121-2132.
    PubMed     Abstract available


  146. WALTERS MC
    Sickle marrow: double, double toil and trouble.
    Blood. 2020;135:2017-2018.
    PubMed    


  147. PARK SY, Matte A, Jung Y, Ryu J, et al
    Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion.
    Blood. 2020;135:2071-2084.
    PubMed     Abstract available


    May 2020
  148. DEBAUN MR
    Initiating adjunct low-dose hydroxyurea therapy for stroke prevention in children with SCA during the COVID-19 pandemic.
    Blood. 2020;135:1997-1999.
    PubMed    


  149. KHANDROS E, Huang P, Peslak SA, Sharma M, et al
    Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
    Blood. 2020;135:1957-1968.
    PubMed     Abstract available


  150. PETZER V, Tymoszuk P, Asshoff M, Carvalho J, et al
    A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the Anemia of Chronic Disease.
    Blood. 2020 May 21. pii: 456038. doi: 10.1182/blood.2019004653.
    PubMed     Abstract available


  151. SUN L, Babushok DV
    Secondary myelodysplastic syndrome and leukemia in acquired aplastic anemia and paroxysmal nocturnal hemoglobinuria.
    Blood. 2020 May 19. pii: 456026. doi: 10.1182/blood.2019000940.
    PubMed     Abstract available


  152. GORDEUK VR
    Sickle cell vaso-occlusion: the clot thickens.
    Blood. 2020;135:1726-1727.
    PubMed    


  153. SPARKENBAUGH EM, Chen C, Brzoska T, Nguyen J, et al
    Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease.
    Blood. 2020;135:1783-1787.
    PubMed     Abstract available


  154. THOMES RM, Rosenstein LJ
    Pernicious anemia.
    Blood. 2020;135:1719.
    PubMed    


    April 2020
  155. SCHINDLER D, Kalb R
    Disease and mutation: correlations coming to fruition.
    Blood. 2020;135:1514-1515.
    PubMed    


  156. APRILE A, Gulino A, Storto M, Villa I, et al
    Hematopoietic stem cell function in beta-thalassemia is impaired and is rescued by targeting the bone marrow niche.
    Blood. 2020 Apr 28. pii: 454666. doi: 10.1182/blood.2019002721.
    PubMed     Abstract available


  157. LIM SP, Costantini B, Mian SA, Perez Abellan P, et al
    Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction.
    Blood. 2020 Apr 15. pii: 454391. doi: 10.1182/blood.2019001347.
    PubMed     Abstract available


  158. SVATON M, Skvarova Kramarzova K, Kanderova V, Mancikova A, et al
    A homozygous deletion in the SLC19A1 gene as a cause of folate-dependent recurrent megaloblastic anemia.
    Blood. 2020 Apr 10. pii: 454359. doi: 10.1182/blood.2019003178.
    PubMed    


  159. VAN ZEVENTER IA, de Graaf AO, Wouters HJCM, van der Reijden BA, et al
    Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals.
    Blood. 2020;135:1161-1170.
    PubMed     Abstract available


  160. STEENSMA DP
    Does clonal hematopoiesis explain unexplained anemia?
    Blood. 2020;135:1080-1082.
    PubMed    


  161. GHANNAM JY, Xu X, Maric I, Dillon L, et al
    Baseline TP53 mutations in adults with SCD developing myeloid malignancy following hematopoietic cell transplantation.
    Blood. 2020;135:1185-1188.
    PubMed    


    March 2020
  162. SARAF SL
    Heme A1M'ed at the kidney in sickle cell disease.
    Blood. 2020;135:979-981.
    PubMed    


  163. OFORI-ACQUAH SF, Hazra R, Orikogbo OO, Crosby D, et al
    Hemopexin deficiency promotes acute kidney injury in sickle cell disease.
    Blood. 2020;135:1044-1048.
    PubMed     Abstract available


  164. BRODSKY RA
    A complementary new drug for PNH.
    Blood. 2020;135:884-885.
    PubMed    


  165. ROTH A, Nishimura JI, Nagy Z, Gaal-Weisinger J, et al
    The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria.
    Blood. 2020;135:912-920.
    PubMed     Abstract available


    February 2020
  166. JUNG M, Ramanagoudr-Bhojappa R, van Twest S, Rosti RO, et al
    Association of clinical severity with FANCB variant type in Fanconi anemia.
    Blood. 2020 Feb 27. pii: 452579. doi: 10.1182/blood.2019003249.
    PubMed     Abstract available


  167. GANZ T
    Drugging erythroferrone to treat anemias.
    Blood. 2020;135:516-518.
    PubMed    


  168. AREZES J, Foy N, McHugh K, Quinkert D, et al
    Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia.
    Blood. 2020;135:547-557.
    PubMed     Abstract available


    January 2020
  169. PENA VN, Naik RP
    Paroxysmal cold hemoglobinuria: a unique constellation of peripheral smear findings.
    Blood. 2020;135:393.
    PubMed    


  170. ANAND I, Gupta P
    How I treat Anemia in Heart Failure.
    Blood. 2020 Jan 2. pii: 430052. doi: 10.1182/blood.2019004004.
    PubMed     Abstract available


    December 2019
  171. YANG G, Hanna CM
    Hematopoietic findings in a patient with scurvy.
    Blood. 2019;134:2330.
    PubMed    


  172. COOPER DM, Liem RI
    Translating exercise benefits in sickle cell disease.
    Blood. 2019;134:2227-2229.
    PubMed    


  173. MERLET AN, Messonnier LA, Coudy-Gandilhon C, Bechet D, et al
    Beneficial effects of endurance exercise training on skeletal muscle microvasculature in sickle cell disease patients.
    Blood. 2019;134:2233-2241.
    PubMed     Abstract available


  174. STENGER EO, Shenoy S, Krishnamurti L
    How I treat sickle cell disease with hematopoietic cell transplantation.
    Blood. 2019;134:2249-2260.
    PubMed     Abstract available


    November 2019
  175. SAHIN I, Niroula R
    Erythrophagocytosis on bone marrow found in severe autoimmune hemolytic anemia with reticulocytopenia.
    Blood. 2019;134:1877.
    PubMed    


  176. CUNNINGHAM-RUNDLES C
    Common variable immune deficiency: case studies.
    Blood. 2019;134:1787-1795.
    PubMed     Abstract available


  177. CHEN JJ, Zhang S
    Heme-regulated eIF2alpha kinase in erythropoiesis and hemoglobinopathies.
    Blood. 2019;134:1697-1707.
    PubMed     Abstract available


  178. MIANO M, Eikema DJ, de la Fuente J, Bosman P, et al
    Stem Cell Transplantation for Diamond-Blackfan Anemia. a Retrospective Study on Behalf of Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (EBMT).
    Blood. 2019;134.
    PubMed     Abstract available


  179. LING T, Birger Y, Stankiewicz MJ, Ben-Haim N, et al
    Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis.
    Blood. 2019;134:1619-1631.
    PubMed     Abstract available


    October 2019
  180. VINANICA N, Yong A, Wong D, Png YT, et al
    Specific stimulation of T lymphocytes with erythropoietin for adoptive immunotherapy.
    Blood. 2019 Oct 31. pii: 422689. doi: 10.1182/blood.2019001645.
    PubMed     Abstract available


  181. XAVIER-FERRUCIO J, Scanlon V, Li X, Zhang PX, et al
    Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.
    Blood. 2019;134:1547-1557.
    PubMed     Abstract available


  182. HUA P, Roy NB, de la Fuente J, Wang G, et al
    Single cell analysis of bone marrow derived CD34+ cells from children with sickle cell disease and thalassemia.
    Blood. 2019 Oct 16. pii: 387151. doi: 10.1182/blood.2019002301.
    PubMed    


  183. MAGRIN E, Miccio A, Cavazzana M
    Lentiviral and genome-editing strategies for the treatment of beta-hemoglobinopathies.
    Blood. 2019;134:1203-1213.
    PubMed     Abstract available


  184. CUTTS A, Vavoulis DV, Petrou M, Smith F, et al
    A method for noninvasive prenatal diagnosis of monogenic autosomal recessive disorders.
    Blood. 2019;134:1190-1193.
    PubMed    


    August 2019
  185. LIU Y, Zhong H, Bao W, Mendelson A, et al
    Patrolling monocytes scavenge endothelial-adherent sickle RBCs: a novel mechanism of inhibition of vaso-occlusion in SCD.
    Blood. 2019;134:579-590.
    PubMed     Abstract available


  186. CAMASCHELLA C
    GDF11 is not the target of luspatercept.
    Blood. 2019;134:500-501.
    PubMed    


    July 2019
  187. KAGEYAMA Y, Miwa H, Tawara I, Ohishi K, et al
    A population of CD20(+)CD27(+)CD43(+)CD38(lo/int) B1 cells in PNH are missing GPI-anchored proteins and harbor PIGA mutations.
    Blood. 2019;134:89-92.
    PubMed    


  188. HADJADJ J, Aladjidi N, Fernandes H, Leverger G, et al
    Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes.
    Blood. 2019;134:9-21.
    PubMed     Abstract available


    June 2019
  189. BABUSHOK DV
    Eltrombopag: wielding a double-edged sword?
    Blood. 2019;133:2555-2556.
    PubMed    


  190. KATO GJ
    Sickle cells and sickle trait in thrombosis.
    Blood. 2019;133:2463.
    PubMed    


  191. SHIN TH, Baek EJ, Corat MAF, Chen S, et al
    CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs.
    Blood. 2019;133:2542-2545.
    PubMed    


  192. FAES C, Ilich A, Sotiaux A, Sparkenbaugh EM, et al
    Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease.
    Blood. 2019;133:2529-2541.
    PubMed     Abstract available


    May 2019
  193. WOOD JC
    Brain O2 reserve in sickle cell disease.
    Blood. 2019;133:2356-2358.
    PubMed    


  194. LE CQ, Myers G, Habara A, Jearawiriyapaisarn N, et al
    Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis.
    Blood. 2019;133:2455-2459.
    PubMed    


  195. TOWNES TM
    A novel therapeutic strategy for beta-thalassemia.
    Blood. 2019;133:2245-2246.
    PubMed    


  196. XU S, Luk K, Yao Q, Shen AH, et al
    Editing aberrant splice sites efficiently restores beta-globin expression in beta-thalassemia.
    Blood. 2019;133:2255-2262.
    PubMed     Abstract available


  197. WARE RE, Thornburg CD
    Your tired, your poor, your huddled masses.
    Blood. 2019;133:2010-2011.
    PubMed    


  198. DE FRANCESCHI L, Lux C, Piel FB, Gianesin B, et al
    Access to emergency departments for acute events and identification of sickle cell disease in refugees.
    Blood. 2019;133:2100-2103.
    PubMed    


  199. SADLER KE, Stucky CL
    Blocking COX-2 for sickle cell pain relief.
    Blood. 2019;133:1924-1925.
    PubMed    


  200. KHASABOVA IA, Uhelski M, Khasabov SG, Gupta K, et al
    Sensitization of nociceptors by prostaglandin E2-glycerol contributes to hyperalgesia in mice with sickle cell disease.
    Blood. 2019;133:1989-1998.
    PubMed     Abstract available


    April 2019
  201. STEINBERG MH
    Primary polymerization prevention.
    Blood. 2019;133:1797-1798.
    PubMed    


  202. HOWARD J, Hemmaway CJ, Telfer P, Layton DM, et al
    A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease.
    Blood. 2019;133:1865-1875.
    PubMed     Abstract available


    March 2019
  203. MARKS EI, Ollila TA
    Acanthocytosis causing chronic hemolysis in a patient with advanced cirrhosis.
    Blood. 2019;133:1518.
    PubMed    


  204. PIGA A, Perrotta S, Gamberini MR, Voskaridou E, et al
    Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with beta-thalassemia.
    Blood. 2019;133:1279-1289.
    PubMed     Abstract available


  205. KENNEDY AL, Shimamura A
    Genetic predisposition to MDS: clinical features and clonal evolution.
    Blood. 2019;133:1071-1085.
    PubMed     Abstract available


  206. TANAKA TN, Bejar R
    MDS overlap disorders and diagnostic boundaries.
    Blood. 2019;133:1086-1095.
    PubMed     Abstract available


    February 2019
  207. BERENTSEN S
    Cold agglutinins: fending off the attack.
    Blood. 2019;133:885-886.
    PubMed    


  208. MARTYN GE, Wienert B, Kurita R, Nakamura Y, et al
    A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site.
    Blood. 2019;133:852-856.
    PubMed     Abstract available


  209. THAKAR MS, Broglie L, Logan B, Artz A, et al
    The Hematopoietic Cell Transplant Comorbidity Index predicts survival after allogeneic transplant for nonmalignant diseases.
    Blood. 2019;133:754-762.
    PubMed     Abstract available


  210. CONNELL NT
    Ravulizumab: a complementary option for PNH.
    Blood. 2019;133:503-504.
    PubMed    


  211. DEBAUN MR, Ghafuri DL, Rodeghier M, Maitra P, et al
    Decreased median survival of adults with sickle cell disease after adjusting for left truncation bias: a pooled analysis.
    Blood. 2019;133:615-617.
    PubMed    


  212. LEE JW, Sicre de Fontbrune F, Wong Lee Lee L, Pessoa V, et al
    Ravulizumab (ALXN1210) vs eculizumab in adult patients with PNH naive to complement inhibitors: the 301 study.
    Blood. 2019;133:530-539.
    PubMed     Abstract available


  213. KULASEKARARAJ AG, Hill A, Rottinghaus ST, Langemeijer S, et al
    Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor-experienced adult patients with PNH: the 302 study.
    Blood. 2019;133:540-549.
    PubMed     Abstract available


    January 2019
  214. DOTY RT, Yan X, Lausted C, Munday AD, et al
    Single-cell analyses demonstrate that a heme-GATA1 feedback loop regulates red cell differentiation.
    Blood. 2019;133:457-469.
    PubMed     Abstract available


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