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Articles published in Blood

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Single Articles


    December 2022
  1. SULLIVAN JC, Comenzo R
    Peripheral agglutination and hemolytic anemia following minor ABO-mismatch hematopoietic progenitor cell transplantation.
    Blood. 2022;140:2412.
    PubMed    


    November 2022
  2. MORIN C, Sharma A, Selukar S, Beasley G, et al
    Diffuse Myocardial Fibrosis Occurs in Young Patients with Sickle Cell Anemia Despite Early Disease Modifying Therapy.
    Blood. 2022 Nov 28:blood.2022018209. doi: 10.1182/blood.2022018209.
    PubMed    


  3. FLAUMENHAFT R
    Platelets: out of shape and misbehaving.
    Blood. 2022;140:2188-2190.
    PubMed    


  4. KUTLAR A
    A-two to the rescue.
    Blood. 2022;140:2187-2188.
    PubMed    


  5. ZHU J, Li H, Aerbajinai W, Kumkhaek C, et al
    Kruppel-like factor 1-GATA1 fusion protein improves the sickle cell disease phenotype in mice both in vitro and in vivo.
    Blood. 2022;140:2276-2289.
    PubMed     Abstract available


  6. OLUPOT-OLUPOT P, Tomlinson G, Williams TN, Tshilolo LMM, et al
    Hydroxyurea is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa.
    Blood. 2022 Nov 14. pii: 487110. doi: 10.1182/blood.2022017051.
    PubMed     Abstract available


  7. LITTLE JA
    RBC, heal thyself: PK activators in SCD.
    Blood. 2022;140:2005-2006.
    PubMed    


  8. XU JZ, Conrey A, Frey I, Gwaabe E, et al
    A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease.
    Blood. 2022;140:2053-2062.
    PubMed     Abstract available


  9. GIBB DR, Hudson KE
    Sickle cell inflammation: is HbS the answer?
    Blood. 2022;140:1921-1923.
    PubMed    


  10. ALLALI S, Rignault-Bricard R, de Montalembert M, Taylor M, et al
    HbS promotes TLR4-mediated monocyte activation and proinflammatory cytokine production in sickle cell disease.
    Blood. 2022;140:1972-1982.
    PubMed     Abstract available


  11. ABDULLAHI S, Sunusi SM, Abba MS, Sani S, et al
    Hydroxyurea for Secondary Stroke Prevention in Children with Sickle Cell Anemia in Nigeria:a Randomized Controlled Trial.
    Blood. 2022 Nov 2. pii: 486968. doi: 10.1182/blood.2022016620.
    PubMed     Abstract available


    October 2022
  12. CARSON JL, Brittenham GM
    How I Treat Anemia with Red Blood Cell Transfusion and Iron.
    Blood. 2022 Oct 31. pii: 486955. doi: 10.1182/blood.2022018521.
    PubMed     Abstract available


  13. KHASABOVA II, Juliette J, Rogness VM, Khasabov SG, et al
    A model of painful vaso-occlusive crisis in mice with sickle cell disease.
    Blood. 2022;140:1826-1830.
    PubMed    


  14. CARSETTI R, Agrati C, Pinto VM, Gianesin B, et al
    Premature aging of the immune system affects the response to SARS-CoV-2 mRNA vaccine in beta-thalassemia: role of an additional dose.
    Blood. 2022;140:1735-1738.
    PubMed    


    September 2022
  15. PECKER LH, Ellsworth P
    Raise the roof, build the floor.
    Blood. 2022;140:1453-1455.
    PubMed    


  16. HEENEY MM, Abboud MR, Githanga J, Inusa BPD, et al
    Ticagrelor vs placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study.
    Blood. 2022;140:1470-1481.
    PubMed     Abstract available


  17. THEIN SL, Sachdev V
    Diffuse myocardial fibrosis as an SCD biomarker.
    Blood. 2022;140:1191-1192.
    PubMed    



  18. Tumburu L, Ghosh-Choudhary S, Seifuddin FT, et al. Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease. Blood. 2021;137(22):3116-3126.
    Blood. 2022;140:1327.
    PubMed    


  19. TORRES LS, Hidalgo A
    NETs in sickle cell disease, quo vadis?
    Blood. 2022;140:938-939.
    PubMed    


  20. CHONAT S, Stowell SR
    A virtuosic CADENZA played by sutimlimab.
    Blood. 2022;140:933-935.
    PubMed    


  21. VATS R, Kaminski TW, Brzoska T, Leech JA, et al
    Liver-to-lung microembolic NETs promote gasdermin D-dependent inflammatory lung injury in sickle cell disease.
    Blood. 2022;140:1020-1037.
    PubMed     Abstract available


  22. ROTH A, Berentsen S, Barcellini W, D'Sa S, et al
    Sutimlimab in patients with cold agglutinin disease: results of the randomized placebo-controlled phase 3 CADENZA trial.
    Blood. 2022;140:980-991.
    PubMed     Abstract available


    August 2022
  23. DEZERN AE
    Playing with fire: unrecognized AA genetic predisposition.
    Blood. 2022;140:805-807.
    PubMed    


  24. MARQUES O, Weiss G, Muckenthaler MU
    The role of iron in chronic inflammatory diseases - from mechanisms to treatment options in Anemia of Inflammation.
    Blood. 2022 Aug 22. pii: 486362. doi: 10.1182/blood.2021013472.
    PubMed     Abstract available


  25. PARROW NL, Fleming RE
    Isn't it ironic: better RBCs by blocking iron.
    Blood. 2022;140:669-670.
    PubMed    



  26. Vats R, Kaminski TW, Ju E-M, et al. P-selectin deficiency promotes liver senescence in sickle cell disease mice. Blood. 2021;137(19):2676-2680.
    Blood. 2022;140:794.
    PubMed    


  27. FATTIZZO B, Cecchi N, Bortolotti M, Giordano G, et al
    Thrombopoietin receptor agonists in adult Evans syndrome: an international multicenter experience.
    Blood. 2022;140:789-792.
    PubMed    


  28. NYFFENEGGER N, Zennadi R, Kalleda N, Flace A, et al
    The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease.
    Blood. 2022;140:769-781.
    PubMed     Abstract available


  29. DOKAL I, Tummala H, Vulliamy T
    Inherited bone marrow failure in the pediatric patient.
    Blood. 2022;140:556-570.
    PubMed     Abstract available


    July 2022
  30. PINCEZ T, Aladjidi N, Heritier S, Garnier N, et al
    Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias.
    Blood. 2022;140:253-261.
    PubMed     Abstract available


  31. NISS O, Detterich JA, Wood JC, Coates TD, et al
    Early initiation of disease-modifying therapy can impede or prevent diffuse myocardial fibrosis in sickle cell anemia.
    Blood. 2022 Jul 20. pii: 485971. doi: 10.1182/blood.2021015303.
    PubMed    


  32. MCREYNOLDS LJ, Rafati M, Wang Y, Ballew BJ, et al
    Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes.
    Blood. 2022 Jul 1. pii: 485762. doi: 10.1182/blood.2022016508.
    PubMed     Abstract available


    June 2022
  33. LANZKRON S, Pecker L
    Pain without gain: steroids and sickle crisis.
    Blood. 2022;139:3678-3679.
    PubMed    


  34. THAKRAL B, Bueso-Ramos CE
    Unexpected presentation of cold agglutinin syndrome with B-acute lymphoblastic leukemia.
    Blood. 2022;139:3778.
    PubMed    


  35. WALTER O, Cougoul P, Maquet J, Bartolucci P, et al
    Risk of vaso-occlusive episode after exposure to corticosteroids in patients with sickle cell disease.
    Blood. 2022;139:3771-3777.
    PubMed     Abstract available


  36. KROLL MH, Rojas-Hernandez C, Yee C
    Hematologic complications of immune checkpoint inhibitors.
    Blood. 2022;139:3594-3604.
    PubMed     Abstract available


  37. GAVRIILAKI E, de Latour RP, Risitano AM
    Advancing therapeutic complement inhibition in hematologic diseases: PNH and beyond.
    Blood. 2022;139:3571-3582.
    PubMed     Abstract available


  38. GERBER GF, Brodsky RA
    Pegcetacoplan for paroxysmal nocturnal hemoglobinuria.
    Blood. 2022;139:3361-3365.
    PubMed     Abstract available


  39. DOTY RT, Fan X, Young DJ, Liang J, et al
    Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis.
    Blood. 2022;139:3439-3449.
    PubMed     Abstract available


    May 2022
  40. ISKANDER D, Warren AJ
    Turning up the HEAT(R3) in Diamond-Blackfan anemia.
    Blood. 2022;139:3101-3102.
    PubMed    


  41. BODINE DM
    Anemia of inflammation is all the RAGE.
    Blood. 2022;139:3106-3107.
    PubMed    


  42. XU JZ, Thein SL
    Revisiting anemia in sickle cell disease and finding the balance with therapeutic approaches.
    Blood. 2022;139:3030-3039.
    PubMed     Abstract available


    April 2022
  43. NOVELLI EM
    Extinguishing the fire in sickle cell anemia.
    Blood. 2022;139:2578-2580.
    PubMed    


  44. DAS NK, Jain C, Sankar A, Schwartz AJ, et al
    Modulation of the HIF2alpha-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis.
    Blood. 2022;139:2547-2552.
    PubMed     Abstract available


  45. WHITE NJ
    What causes malaria anemia?
    Blood. 2022;139:2268-2269.
    PubMed    


  46. MAHAMAR A, Gonzales Hurtado PA, Morrison R, Boone R, et al
    Plasma biomarkers of hemoglobin loss in Plasmodium falciparum-infected children identified by quantitative proteomics.
    Blood. 2022;139:2361-2376.
    PubMed     Abstract available


  47. NWOGBO OV, Loghavi S
    Essential thrombocythemia complicating hemoglobin SC disease and presenting with priapism.
    Blood. 2022;139:2258.
    PubMed    


  48. WANG M, Dingler FA, Patel KJ
    Genotoxic aldehydes in the hematopoietic system.
    Blood. 2022;139:2119-2129.
    PubMed     Abstract available


  49. TOPFER SK, Feng R, Huang P, Ly LC, et al
    Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
    Blood. 2022;139:2107-2118.
    PubMed     Abstract available


    March 2022
  50. CAZZOLA M
    RNA missplicing and ring sideroblasts in MDS.
    Blood. 2022;139:1933-1935.
    PubMed    


  51. WOOD JC
    Pulmonary hypertension in thalassemia: a call to action.
    Blood. 2022;139:1937-1938.
    PubMed    


  52. PINTO VM, Musallam KM, Derchi G, Graziadei G, et al
    Mortality in beta-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization.
    Blood. 2022;139:2080-2083.
    PubMed    


  53. SCHMIDT CQ, Schrezenmeier H, Kavanagh D
    Complement and the prothrombotic state.
    Blood. 2022;139:1954-1972.
    PubMed     Abstract available


  54. DOSUNMU-OGUNBI A, Yuan S, Reynolds M, Giordano L, et al
    SOD2 V16A amplifies vascular dysfunction in sickle cell patients by curtailing mitochondria complex IV activity.
    Blood. 2022;139:1760-1765.
    PubMed     Abstract available


  55. MESSONNIER LA
    Mitochondrial function in sickle cell disease.
    Blood. 2022;139:1616-1617.
    PubMed    


  56. WONTAKAL SN, Britto M, Zhang H, Han Y, et al
    RACGAP1 variants in a sporadic case of CDA III implicate the dysfunction of centralspindlin as the basis of the disease.
    Blood. 2022;139:1413-1418.
    PubMed    


    February 2022
  57. REES DC, Kilinc Y, Unal S, Dampier CD, et al
    A randomized, placebo-controlled, double-blind trial of canakinumab in children and young adults with sickle cell anemia.
    Blood. 2022 Feb 28. pii: 484189. doi: 10.1182/blood.2021013674.
    PubMed     Abstract available


  58. O'DONOHUE MF, Da Costa LM, Lezzerini M, Unal S, et al
    HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia.
    Blood. 2022 Feb 25. pii: 484180. doi: 10.1182/blood.2021011846.
    PubMed     Abstract available


  59. GALLAGHER PG
    Anemia in the pediatric patient.
    Blood. 2022 Feb 25. pii: 484178. doi: 10.1182/blood.2020006479.
    PubMed     Abstract available


  60. MENON AV, Liu J, Tsai HP, Zeng L, et al
    Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease.
    Blood. 2022;139:936-941.
    PubMed     Abstract available


    January 2022
  61. NEUMANN NM, Wen KW
    Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts, thrombocytosis, and mutated JAK2/SF3B1 without anemia.
    Blood. 2022;139:466.
    PubMed    


  62. RAO VK
    Evans syndrome: pathology and genomic hubris.
    Blood. 2022;139:312-313.
    PubMed    


  63. KUMAR D, Prince C, Bennett CM, Briones M, et al
    T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome.
    Blood. 2022;139:369-383.
    PubMed     Abstract available


  64. DULMOVITS BM, Tang Y, Papoin J, He M, et al
    HMGB1-Mediated Restriction of EPO Signaling Contributes to Anemia of Inflammation.
    Blood. 2022 Jan 18. pii: 483547. doi: 10.1182/blood.2021012048.
    PubMed     Abstract available


  65. LUDWIG L, Lareau CA, Bao EL, Liu N, et al
    A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1.
    Blood. 2022 Jan 14. pii: 483530. doi: 10.1182/blood.2021013753.
    PubMed     Abstract available


  66. DHUNPUTH C, Ducassou S, Fernandes H, Picard C, et al
    Abatacept is useful in autoimmune cytopenia with immunopathologic manifestations caused by CTLA-4 defects.
    Blood. 2022;139:300-304.
    PubMed    


    December 2021
  67. PAGLIUCA S, Gurnari C, Awada H, Kishtagari A, et al
    The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders.
    Blood. 2021;138:2781-2798.
    PubMed     Abstract available


  68. TANG A, Strat AN, Rahman M, Zhang H, et al
    Murine bone marrow mesenchymal stromal cells have reduced hematopoietic maintenance ability in sickle cell disease.
    Blood. 2021;138:2570-2582.
    PubMed     Abstract available


  69. PECKER L, Hussain S, Mahesh J, Varadhan R, et al
    Diminished ovarian reserve in young women with sickle cell anemia.
    Blood. 2021 Dec 5. pii: 482897. doi: 10.1182/blood.2021012756.
    PubMed    


  70. MARTIN MERINERO H, Zhang Y, Arjona E, Del Angel G, et al
    Functional characterization of 105 factor H variants associated with aHUS: lessons for variant classification.
    Blood. 2021;138:2185-2201.
    PubMed     Abstract available


    November 2021
  71. DUCHEMANN B, Lazarian G
    Post-SARS-CoV-2 vaccination acute hemolysis in an older man: don't forget to look at the blood smear.
    Blood. 2021;138:2153.
    PubMed    


  72. PINCEZ T, Lee SSK, Ilboudo Y, Preuss M, et al
    Clonal hematopoiesis in sickle cell disease.
    Blood. 2021;138:2148-2152.
    PubMed    


  73. LUZZATTO L
    Control of hemolysis in patients with PNH.
    Blood. 2021;138:1908-1910.
    PubMed    


  74. KULASEKARARAJ AG, Risitano AM, Maciejewski JP, Notaro R, et al
    Phase 2 study of danicopan in patients with paroxysmal nocturnal hemoglobinuria with an inadequate response to eculizumab.
    Blood. 2021;138:1928-1938.
    PubMed     Abstract available


  75. EL SISSY C, Saldman A, Zanetta G, Martins PV, et al
    COVID-19 as a potential trigger of complement-mediated atypical HUS.
    Blood. 2021;138:1777-1782.
    PubMed    


  76. FENG Y, Feng W
    Numerous ring sideroblasts in chronic neutrophilic leukemia.
    Blood. 2021;138:1783.
    PubMed    


  77. ZAIMOKU Y, Patel BA, Adams SD, Shalhoub RN, et al
    HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia.
    Blood. 2021 Nov 1. pii: 477734. doi: 10.1182/blood.2021012895.
    PubMed     Abstract available


    September 2021
  78. HENRY ER, Metaferia B, Li Q, Harper J, et al
    Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
    Blood. 2021;138:1172-1181.
    PubMed     Abstract available


  79. LIU Y, Pal M, Bao W, Shi PA, et al
    Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease.
    Blood. 2021;138:1162-1171.
    PubMed     Abstract available


  80. IRELAND RM, Rees DC
    Two brothers with a novel KLF1 mutation.
    Blood. 2021;138:1087.
    PubMed    


  81. ABRAHAM AA, Tisdale JF
    Gene therapy for sickle cell disease: moving from the bench to the bedside.
    Blood. 2021;138:932-941.
    PubMed     Abstract available


  82. BOLLARD CM
    Introduction to a review series on gene therapy and gene editing for sickle cell disease and hemophilia.
    Blood. 2021;138:913.
    PubMed    


  83. PATEL BA, Groarke EM, Lotter J, Shalhoub RN, et al
    Long-term outcomes in severe aplastic anemia patients treated with immunosuppression and eltrombopag: a phase 2 study.
    Blood. 2021 Sep 15. pii: 476916. doi: 10.1182/blood.2021012130.
    PubMed     Abstract available


    August 2021
  84. COCHRAN T, Li W
    Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation.
    Blood. 2021;138:738.
    PubMed    


  85. XU Z, Mueller R
    Myelodysplastic pure red cell aplasia.
    Blood. 2021;138:500.
    PubMed    


    July 2021
  86. JALINK M, Berentsen S, Castillo J, Treon SPP, et al
    Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome.
    Blood. 2021 Jul 22. pii: 476451. doi: 10.1182/blood.2021012039.
    PubMed    


  87. RICE L, Schwartz MR
    Sickle cell hepatopathy with spur cell anemia.
    Blood. 2021;138:283.
    PubMed    


  88. GERBER GF, Yuan X, Yu J, Cher BAY, et al
    COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:3670-3673.
    PubMed    


    June 2021
  89. MORENO C
    Autoimmune cytopenia and CLL ride together.
    Blood. 2021;137:3464-3465.
    PubMed    


  90. MARTIN MERINERO H, Subias M, Pereda A, Gomez-Rubio E, et al
    Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases.
    Blood. 2021;137:3484-3494.
    PubMed     Abstract available


  91. REJESKI K, Perez Perez A, Sesques P, Hoster E, et al
    CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma.
    Blood. 2021 Jun 24. pii: 476241. doi: 10.1182/blood.2020010543.
    PubMed     Abstract available


  92. PSATHA N, Georgakopoulou A, Li C, Nandakumar V, et al
    Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo.
    Blood. 2021 Jun 4. pii: 476068. doi: 10.1182/blood.2020010020.
    PubMed     Abstract available


  93. RARICK KR, Pritchard KA
    The sickle erythrocyte yields another DAMP.
    Blood. 2021;137:3010-3011.
    PubMed    


  94. JONES RJ, DeBaun MR
    Leukemia after gene therapy for sickle cell disease: insertional mutagenesis, busulfan, both or neither.
    Blood. 2021 Jun 3. pii: 476065. doi: 10.1182/blood.2021011488.
    PubMed     Abstract available


  95. TUMBURU L, Ghosh-Choudhary S, Seifuddin FT, Barbu EA, et al
    Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease.
    Blood. 2021;137:3116-3126.
    PubMed     Abstract available


    May 2021
  96. RAB MAE, Bos J, van Oirschot BA, van Straaten S, et al
    Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy.
    Blood. 2021;137:2997-3001.
    PubMed    


  97. MANWANI D
    P-selectin and sickle cell disease: a balancing act.
    Blood. 2021;137:2573-2574.
    PubMed    


  98. VATS R, Kaminski TW, Ju EM, Brozska T, et al
    P-selectin deficiency promotes liver senescence in sickle cell disease mice.
    Blood. 2021;137:2676-2680.
    PubMed     Abstract available


  99. BRODSKY RA
    Eculizumab and aHUS: to stop or not.
    Blood. 2021;137:2419-2420.
    PubMed    


  100. FAKHOURI F, Fila M, Hummel A, Ribes D, et al
    Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study.
    Blood. 2021;137:2438-2449.
    PubMed     Abstract available


    April 2021
  101. CERCAMONDI CI, Stoffel N, Moretti D, Zoller T, et al
    Iron homeostasis during anemia of inflammation: a prospective study in patients with tuberculosis.
    Blood. 2021 Apr 19. pii: 475787. doi: 10.1182/blood.2020010562.
    PubMed     Abstract available


  102. SHAH N
    ELIPSIS: developing tools to better understand VOC in SCD.
    Blood. 2021;137:1987-1988.
    PubMed    


  103. GURNARI C, Maciejewski JP
    How I manage acquired pure red cell aplasia in adults.
    Blood. 2021;137:2001-2009.
    PubMed     Abstract available


  104. PITTMAN DD, Hines PC, Beidler D, Rybin D, et al
    Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers.
    Blood. 2021;137:2010-2020.
    PubMed     Abstract available


  105. TURNIS ME, Kaminska E, Smith KH, Kartchner BJ, et al
    Requirement for antiapoptotic MCL-1 during early erythropoiesis.
    Blood. 2021;137:1945-1958.
    PubMed     Abstract available


    March 2021
  106. GONG Y, Zhang X, Zhang Q, Zhang Y, et al
    A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the gamma-globin gene in beta-thalassemia.
    Blood. 2021;137:1652-1657.
    PubMed     Abstract available


  107. ZHU C, Lian Y, Wang C, Wu P, et al
    Single-cell transcriptomics dissects hematopoietic cell destruction and T cell engagement in aplastic anemia.
    Blood. 2021 Mar 24. pii: 475591. doi: 10.1182/blood.2020008966.
    PubMed     Abstract available


  108. HOSOKAWA K, Mizumaki H, Yoroidaka T, Maruyama H, et al
    HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia.
    Blood. 2021 Mar 22. pii: 475586. doi: 10.1182/blood.2020010586.
    PubMed    


  109. BRUGNARA C
    Less (Fe) is more (Hb) in SCA.
    Blood. 2021;137:1446-1447.
    PubMed    


  110. ANSARI J, Senchenkova EY, Vital SA, Al-Yafeai Z, et al
    Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease.
    Blood. 2021;137:1538-1549.
    PubMed     Abstract available


  111. ELDAR D, Ganzel C
    Erythrophagocytosis in a young adult with mycoplasma pneumonia-induced paroxysmal cold hemoglobinuria.
    Blood. 2021;137:1432.
    PubMed    


  112. BERENTSEN S
    How I treat cold agglutinin disease.
    Blood. 2021;137:1295-1303.
    PubMed     Abstract available


  113. BRODSKY RA
    How I treat paroxysmal nocturnal hemoglobinuria.
    Blood. 2021;137:1304-1309.
    PubMed     Abstract available


  114. ZHABYEYEV P, Oudit GY
    Sickle cell disease, interleukin-18, and arrhythmias.
    Blood. 2021;137:1138-1139.
    PubMed    


  115. GUPTA A, Fei YD, Kim TY, Xie A, et al
    IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.
    Blood. 2021;137:1208-1218.
    PubMed     Abstract available


    February 2021
  116. WACHTER F, Archer NM
    Autoimmune hemolytic anemia complicated by parvovirus infection.
    Blood. 2021;137:1130.
    PubMed    


  117. GU Y, Yang R, Yang Y, Zhao Y, et al
    IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.
    Blood. 2021;137:945-958.
    PubMed     Abstract available


  118. AL-SAMKARI H
    Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
    Blood. 2021;137:888-895.
    PubMed     Abstract available


  119. WARE RE, Dertinger SD
    There's safety in numbers.
    Blood. 2021;137:729-731.
    PubMed    


  120. REES DC
    Hydroxyurea: coming to conclusions on safety.
    Blood. 2021;137:728-729.
    PubMed    


  121. GILLE AS, Pondarre C, Dalle JH, Bernaudin F, et al
    Hydroxyurea does not affect the spermatogonial pool in prepubertal patients with sickle cell disease.
    Blood. 2021;137:856-859.
    PubMed    


  122. JOSEPH L, Jean C, Manceau S, Chalas C, et al
    Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
    Blood. 2021;137:826-829.
    PubMed     Abstract available


  123. SHENG Y, Ma R, Yu C, Wu Q, et al
    Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
    Blood. 2021;137:610-623.
    PubMed     Abstract available


    January 2021
  124. BADAT M, Davies JOJ, Fisher CA, Downes DJ, et al
    A remarkable case of HbH disease illustrates the relative contributions of the alpha-globin enhancers to gene expression.
    Blood. 2021;137:572-575.
    PubMed    


  125. DEANS AJ
    Fanconi anemia, put to sleep.
    Blood. 2021;137:286-288.
    PubMed    


  126. THOMAS M, Scully M
    How I Treat Microangiopathic Hemolytic Anemia in Patients with Cancer.
    Blood. 2021 Jan 21. pii: 475029. doi: 10.1182/blood.2019003810.
    PubMed     Abstract available


  127. CAZZOLA M
    Introduction to a How I Treat Series on Acquired Hemolytic Anemia.
    Blood. 2021 Jan 21. pii: 475027. doi: 10.1182/blood.2020009747.
    PubMed    


  128. BARCELLINI W, Fattizzo B
    How I treat warm autoimmune hemolytic anemia.
    Blood. 2021 Jan 21. pii: 475030. doi: 10.1182/blood.2019003808.
    PubMed     Abstract available


  129. PIRENNE F
    Heme control to major B (cell): are you listening?
    Blood. 2021;137:153-154.
    PubMed    


  130. PAL M, Bao W, Wang R, Liu Y, et al
    Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease.
    Blood. 2021;137:269-280.
    PubMed     Abstract available


  131. MU A, Hira A, Niwa A, Osawa M, et al
    Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
    Blood. 2021 Jan 12. pii: 474923. doi: 10.1182/blood.2020009111.
    PubMed     Abstract available


  132. SALIB C, Hussein S
    A case of hairy cell leukemia with markedly hypocellular marrow mimicking aplastic anemia.
    Blood. 2021;137:142.
    PubMed    


    December 2020
  133. SICA M, Pellecchia A, De Angioletti M, Caocci G, et al
    Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH.
    Blood. 2020;136:3082-3085.
    PubMed    


  134. MARIANI R, Liu H
    Severe transient pancytopenia with dyserythropoiesis and dysmegakaryopoiesis in COVID-19-associated MIS-C.
    Blood. 2020;136:2964.
    PubMed    


  135. ARORA S, Ganapathi KA
    Prominent pseudo-Gaucher cells in a patient with beta-thalassemia intermedia and plasma cell myeloma.
    Blood. 2020;136:2839.
    PubMed    


  136. PARROW NL, Violet PC, Ajit George N, Ali F, et al
    Dietary Iron Restriction Improves Markers of Disease Severity in Murine Sickle Cell Anemia.
    Blood. 2020 Dec 8. pii: 474426. doi: 10.1182/blood.2020006919.
    PubMed    


    November 2020
  137. ABKOWITZ JL
    A simple Rx for congenital erythropoietic porphyria.
    Blood. 2020;136:2371-2372.
    PubMed    


    October 2020
  138. DEWARRAT N, Blum S
    Heavy metal.
    Blood. 2020;136:1993.
    PubMed    


    September 2020
  139. ARJONA E, Huerta A, Goicoechea de Jorge E, Rodriguez de Cordoba S, et al
    Familial risk of developing atypical hemolytic-uremic syndrome.
    Blood. 2020;136:1558-1561.
    PubMed    


  140. KIM-SHAPIRO DB, Gladwin MT
    Arginine for mitochondrial oxidative enzymopathy.
    Blood. 2020;136:1376-1378.
    PubMed    


  141. MORRIS CR, Brown LAS, Reynolds M, Dampier CD, et al
    Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain.
    Blood. 2020;136:1402-1406.
    PubMed     Abstract available


  142. LUZZATTO L, Ally M, Notaro R
    Glucose-6-phosphate dehydrogenase deficiency.
    Blood. 2020;136:1225-1240.
    PubMed     Abstract available


  143. SCHELL B, Fenneteau O
    Brandalise syndrome: a rare inclusion cell disease.
    Blood. 2020;136:1373.
    PubMed    


  144. RISINGER M, Kalfa TA
    Red cell membrane disorders: structure meets function.
    Blood. 2020;136:1250-1261.
    PubMed     Abstract available


  145. CAZZOLA M
    Introduction to a review series on inherited anemias.
    Blood. 2020;136:1215-1216.
    PubMed    


  146. IOLASCON A, Andolfo I, Russo R
    Congenital dyserythropoietic anemias.
    Blood. 2020;136:1274-1283.
    PubMed     Abstract available


  147. GRACE RF, Barcellini W
    Management of pyruvate kinase deficiency in children and adults.
    Blood. 2020;136:1241-1249.
    PubMed     Abstract available


  148. BROUSSE V, Connes P
    Vasomotor hyperresponsiveness in SCD.
    Blood. 2020;136:1120-1121.
    PubMed    


  149. VELUSWAMY S, Shah P, Khaleel M, Thuptimdang W, et al
    Progressive vasoconstriction with sequential thermal stimulation indicates vascular dysautonomia in sickle cell disease.
    Blood. 2020;136:1191-1200.
    PubMed     Abstract available


    August 2020
  150. VOIT RA, Grace RF
    Pyruvate kinase deficiency in a newborn with extramedullary hematopoiesis in the skin.
    Blood. 2020;136:770.
    PubMed    


    July 2020
  151. CARLESSO N
    Targeting the bone marrow niche in hemoglobinopathies.
    Blood. 2020;136:529-531.
    PubMed    


  152. BRAZAUSKAS R, Scigliuolo GM, Wang HL, Cappelli B, et al
    Risk score to predict event-free survival after hematopoietic cell transplant for sickle cell disease.
    Blood. 2020;136:623-626.
    PubMed     Abstract available


  153. ROTH A
    Do temperature and time matter in cold agglutinin disease?
    Blood. 2020;136:380-381.
    PubMed    


  154. BERENTSEN S, Barcellini W, D'Sa S, Randen U, et al
    Cold agglutinin disease revisited: a multinational, observational study of 232 patients.
    Blood. 2020;136:480-488.
    PubMed     Abstract available


  155. KATO GJ
    Sickle particulars of microparticles.
    Blood. 2020;136:154-155.
    PubMed    


  156. GARNIER Y, Ferdinand S, Garnier M, Cita KC, et al
    Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties.
    Blood. 2020;136:247-256.
    PubMed     Abstract available


  157. EVANS EL, Povstyan OV, De Vecchis D, Macrae F, et al
    RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis.
    Blood. 2020;136:140-144.
    PubMed    


    June 2020
  158. KHAN R, Menard M, Jen CC, Chen X, et al
    Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP.
    Blood. 2020;135:2420-2424.
    PubMed     Abstract available


  159. CHEN BY, Song J, Hu CL, Chen SB, et al
    SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
    Blood. 2020;135:2271-2285.
    PubMed     Abstract available


  160. HUANG P, Peslak SA, Lan X, Khandros E, et al
    The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression.
    Blood. 2020;135:2121-2132.
    PubMed     Abstract available


  161. WALTERS MC
    Sickle marrow: double, double toil and trouble.
    Blood. 2020;135:2017-2018.
    PubMed    


  162. PARK SY, Matte A, Jung Y, Ryu J, et al
    Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion.
    Blood. 2020;135:2071-2084.
    PubMed     Abstract available


    May 2020
  163. KHANDROS E, Huang P, Peslak SA, Sharma M, et al
    Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
    Blood. 2020;135:1957-1968.
    PubMed     Abstract available


  164. GORDEUK VR
    Sickle cell vaso-occlusion: the clot thickens.
    Blood. 2020;135:1726-1727.
    PubMed    


  165. SPARKENBAUGH EM, Chen C, Brzoska T, Nguyen J, et al
    Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease.
    Blood. 2020;135:1783-1787.
    PubMed     Abstract available


    April 2020
  166. SCHINDLER D, Kalb R
    Disease and mutation: correlations coming to fruition.
    Blood. 2020;135:1514-1515.
    PubMed    


  167. APRILE A, Gulino A, Storto M, Villa I, et al
    Hematopoietic stem cell function in beta-thalassemia is impaired and is rescued by targeting the bone marrow niche.
    Blood. 2020 Apr 28. pii: 454666. doi: 10.1182/blood.2019002721.
    PubMed     Abstract available


  168. GHANNAM JY, Xu X, Maric I, Dillon L, et al
    Baseline TP53 mutations in adults with SCD developing myeloid malignancy following hematopoietic cell transplantation.
    Blood. 2020;135:1185-1188.
    PubMed    


    March 2020
  169. SARAF SL
    Heme A1M'ed at the kidney in sickle cell disease.
    Blood. 2020;135:979-981.
    PubMed    


  170. OFORI-ACQUAH SF, Hazra R, Orikogbo OO, Crosby D, et al
    Hemopexin deficiency promotes acute kidney injury in sickle cell disease.
    Blood. 2020;135:1044-1048.
    PubMed     Abstract available


  171. BRODSKY RA
    A complementary new drug for PNH.
    Blood. 2020;135:884-885.
    PubMed    


  172. ROTH A, Nishimura JI, Nagy Z, Gaal-Weisinger J, et al
    The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria.
    Blood. 2020;135:912-920.
    PubMed     Abstract available


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