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Anemia

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March 2023
1. AYOUB PG, Kohn DB
   beta-Thalassemia: all about that base, no cutting.
   Blood. 2023;141:1098-1099.
   PubMed    
   
   
   
2. MATSON DR, Matkovic E
   Peripheral erythrophagocytosis in paroxysmal cold hemoglobinuria.
   Blood. 2023;141:1233.
   PubMed    
   
   
   
3. HARDOUIN G, Antoniou P, Martinucci P, Felix T, et al
   Adenine base editor-mediated correction of the common and severe IVS1-110 (G>A) beta-thalassemia mutation.
   Blood. 2023;141:1169-1179.
   PubMed     Abstract available
   
   
   
4. 
   Ludwig LS, Lareau CA, Bao EL, et al. Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1. Blood. 2022;139(16):2534-2546.
   Blood. 2023;141:1094.
   PubMed    
   
   
   
5. FAKHOURI F, Schwotzer N, Fremeaux-Bacchi V
   How I diagnose and treat atypical hemolytic uremic syndrome.
   Blood. 2023;141:984-995.
   PubMed     Abstract available
   
   
   February 2023
6. OYEDEJI CI, Artz AS, Cohen HJ
   How I Treat Anemia in Older Adults.
   Blood. 2023 Feb 24:blood.2022017626. doi: 10.1182/blood.2022017626.
   PubMed     Abstract available
   
   
   
7. QUINN CT
   Hydroxyurea: how much is enough?
   Blood. 2023;141:813-814.
   PubMed    
   
   
   
8. 
   Camaschella C. Iron deficiency. Blood. 2019;133(1):30-39.
   Blood. 2023;141:682.
   PubMed    
   
   
   January 2023
9. FATTIZZO B, Bortolotti M, Fantini NN, Glenthoj A, et al
   AUTOIMMUNE HEMOLYTIC ANEMIA DURING PREGNANCY AND PUERPERIUM: AN INTERNATIONAL MULTI-CENTER EXPERIENCE.
   Blood. 2023 Jan 27:blood.2022018890. doi: 10.1182/blood.2022018890.
   PubMed     Abstract available
   
   
   
10. WOOD JC
    Anemia and brain hypoxia.
    Blood. 2023;141:327-328.
    PubMed    
    
    
    
11. 
    Barcellini W, Fattizzo B. How I treat warm autoimmune hemolytic anemia. Blood. 2021;137(10):1283-1294.
    Blood. 2023;141:438-439.
    PubMed    
    
    
    
12. PARROW NL, Fleming RE
    Transferrin receptor 1: keeper of HFE.
    Blood. 2023;141:332-333.
    PubMed    
    
    
    
13. TARFI S, Badaoui B
    Four genetic red cell disorders in one.
    Blood. 2023;141:436.
    PubMed    
    
    
    
14. XIAO X, Moschetta GA, Xu Y, Fisher AL, et al
    Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in beta-thalassemia.
    Blood. 2023;141:422-432.
    PubMed     Abstract available
    
    
    
15. BROUSSE V
    Ups and downs in the treatment of sickle cell disease.
    Blood. 2023;141:125-127.
    PubMed    
    
    
    
16. DAS NK, Shah YM
    (De)ironing out sickle cell disease.
    Blood. 2023;141:129-130.
    PubMed    
    
    
    
17. KARAMATIC CREW V, Tilley LA, Satchwell TJ, AlSubhi SA, et al
    Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens.
    Blood. 2023;141:135-146.
    PubMed     Abstract available
    
    
    
18. CURTIS SA, Novelli EM
    Is CBD ready for prime time in sickle cell disease?
    Blood. 2023;141:132-133.
    PubMed    
    
    
    
19. LI H, Kazmi JS, Lee S, Zhang D, et al
    Dietary iron restriction protects against vaso-occlusion and organ damage in murine sickle cell disease.
    Blood. 2023;141:194-199.
    PubMed     Abstract available
    
    
    
20. CHERUKURY HM, Argueta DA, Garcia N, Fouda R, et al
    Cannabidiol attenuates hyperalgesia in a mouse model of sickle cell disease.
    Blood. 2023;141:203-208.
    PubMed    
    
    
    
21. DAMPIER CD, Telen MJ, Wun T, Brown RC, et al
    A randomized clinical trial of the efficacy and safety of rivipansel for sickle cell vaso-occlusive crisis.
    Blood. 2023;141:168-179.
    PubMed     Abstract available
    
    
    
22. GROARKE EM, Feng X, Aggarwal N, Manley AL, et al
    Efficacy of JAK1/2 inhibition in murine immune bone marrow failure.
    Blood. 2023;141:72-89.
    PubMed     Abstract available
    
    
    
23. GRIFFIN M, Muus P, Munir T, Nagumantry S, et al
    Experience of compassionate-use pegcetacoplan for paroxysmal nocturnal hemoglobinuria.
    Blood. 2023;141:116-120.
    PubMed    
    
    
    December 2022
24. 
    Galli A, Todisco G, Catamo E, et al. Relationship between clone metrics and clinical outcome in clonal cytopenia. Blood. 2021;138(11):965-976.
    Blood. 2022;140:2858.
    PubMed    
    
    
    
25. SULLIVAN JC, Comenzo R
    Peripheral agglutination and hemolytic anemia following minor ABO-mismatch hematopoietic progenitor cell transplantation.
    Blood. 2022;140:2412.
    PubMed    
    
    
    November 2022
26. MORIN C, Sharma A, Selukar S, Beasley G, et al
    Diffuse Myocardial Fibrosis Occurs in Young Patients with Sickle Cell Anemia Despite Early Disease Modifying Therapy.
    Blood. 2022 Nov 28:blood.2022018209. doi: 10.1182/blood.2022018209.
    PubMed    
    
    
    
27. FLAUMENHAFT R
    Platelets: out of shape and misbehaving.
    Blood. 2022;140:2188-2190.
    PubMed    
    
    
    
28. KUTLAR A
    A-two to the rescue.
    Blood. 2022;140:2187-2188.
    PubMed    
    
    
    
29. ZHU J, Li H, Aerbajinai W, Kumkhaek C, et al
    Kruppel-like factor 1-GATA1 fusion protein improves the sickle cell disease phenotype in mice both in vitro and in vivo.
    Blood. 2022;140:2276-2289.
    PubMed     Abstract available
    
    
    
30. OLUPOT-OLUPOT P, Tomlinson G, Williams TN, Tshilolo LMM, et al
    Hydroxyurea is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa.
    Blood. 2022 Nov 14. pii: 487110. doi: 10.1182/blood.2022017051.
    PubMed     Abstract available
    
    
    
31. LITTLE JA
    RBC, heal thyself: PK activators in SCD.
    Blood. 2022;140:2005-2006.
    PubMed    
    
    
    
32. XU JZ, Conrey A, Frey I, Gwaabe E, et al
    A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease.
    Blood. 2022;140:2053-2062.
    PubMed     Abstract available
    
    
    
33. GIBB DR, Hudson KE
    Sickle cell inflammation: is HbS the answer?
    Blood. 2022;140:1921-1923.
    PubMed    
    
    
    
34. ALLALI S, Rignault-Bricard R, de Montalembert M, Taylor M, et al
    HbS promotes TLR4-mediated monocyte activation and proinflammatory cytokine production in sickle cell disease.
    Blood. 2022;140:1972-1982.
    PubMed     Abstract available
    
    
    
35. ABDULLAHI S, Sunusi SM, Abba MS, Sani S, et al
    Hydroxyurea for Secondary Stroke Prevention in Children with Sickle Cell Anemia in Nigeria:a Randomized Controlled Trial.
    Blood. 2022 Nov 2. pii: 486968. doi: 10.1182/blood.2022016620.
    PubMed     Abstract available
    
    
    October 2022
36. CARSON JL, Brittenham GM
    How I Treat Anemia with Red Blood Cell Transfusion and Iron.
    Blood. 2022 Oct 31. pii: 486955. doi: 10.1182/blood.2022018521.
    PubMed     Abstract available
    
    
    
37. KHASABOVA II, Juliette J, Rogness VM, Khasabov SG, et al
    A model of painful vaso-occlusive crisis in mice with sickle cell disease.
    Blood. 2022;140:1826-1830.
    PubMed    
    
    
    
38. CARSETTI R, Agrati C, Pinto VM, Gianesin B, et al
    Premature aging of the immune system affects the response to SARS-CoV-2 mRNA vaccine in beta-thalassemia: role of an additional dose.
    Blood. 2022;140:1735-1738.
    PubMed    
    
    
    September 2022
39. PECKER LH, Ellsworth P
    Raise the roof, build the floor.
    Blood. 2022;140:1453-1455.
    PubMed    
    
    
    
40. HEENEY MM, Abboud MR, Githanga J, Inusa BPD, et al
    Ticagrelor vs placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study.
    Blood. 2022;140:1470-1481.
    PubMed     Abstract available
    
    
    
41. THEIN SL, Sachdev V
    Diffuse myocardial fibrosis as an SCD biomarker.
    Blood. 2022;140:1191-1192.
    PubMed    
    
    
    
42. 
    Tumburu L, Ghosh-Choudhary S, Seifuddin FT, et al. Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease. Blood. 2021;137(22):3116-3126.
    Blood. 2022;140:1327.
    PubMed    
    
    
    
43. TORRES LS, Hidalgo A
    NETs in sickle cell disease, quo vadis?
    Blood. 2022;140:938-939.
    PubMed    
    
    
    
44. CHONAT S, Stowell SR
    A virtuosic CADENZA played by sutimlimab.
    Blood. 2022;140:933-935.
    PubMed    
    
    
    
45. VATS R, Kaminski TW, Brzoska T, Leech JA, et al
    Liver-to-lung microembolic NETs promote gasdermin D-dependent inflammatory lung injury in sickle cell disease.
    Blood. 2022;140:1020-1037.
    PubMed     Abstract available
    
    
    
46. ROTH A, Berentsen S, Barcellini W, D'Sa S, et al
    Sutimlimab in patients with cold agglutinin disease: results of the randomized placebo-controlled phase 3 CADENZA trial.
    Blood. 2022;140:980-991.
    PubMed     Abstract available
    
    
    August 2022
47. HULBERT ML, Fields ME, Guilliams KP, Bijlani P, et al
    Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease.
    Blood. 2022 Aug 30. pii: 486449. doi: 10.1182/blood.2022016618.
    PubMed     Abstract available
    
    
    
48. DEZERN AE
    Playing with fire: unrecognized AA genetic predisposition.
    Blood. 2022;140:805-807.
    PubMed    
    
    
    
49. MARQUES O, Weiss G, Muckenthaler MU
    The role of iron in chronic inflammatory diseases - from mechanisms to treatment options in Anemia of Inflammation.
    Blood. 2022 Aug 22. pii: 486362. doi: 10.1182/blood.2021013472.
    PubMed     Abstract available
    
    
    
50. PARROW NL, Fleming RE
    Isn't it ironic: better RBCs by blocking iron.
    Blood. 2022;140:669-670.
    PubMed    
    
    
    
51. 
    Vats R, Kaminski TW, Ju E-M, et al. P-selectin deficiency promotes liver senescence in sickle cell disease mice. Blood. 2021;137(19):2676-2680.
    Blood. 2022;140:794.
    PubMed    
    
    
    
52. FATTIZZO B, Cecchi N, Bortolotti M, Giordano G, et al
    Thrombopoietin receptor agonists in adult Evans syndrome: an international multicenter experience.
    Blood. 2022;140:789-792.
    PubMed    
    
    
    
53. NYFFENEGGER N, Zennadi R, Kalleda N, Flace A, et al
    The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease.
    Blood. 2022;140:769-781.
    PubMed     Abstract available
    
    
    
54. DOKAL I, Tummala H, Vulliamy T
    Inherited bone marrow failure in the pediatric patient.
    Blood. 2022;140:556-570.
    PubMed     Abstract available
    
    
    July 2022
55. PINCEZ T, Aladjidi N, Heritier S, Garnier N, et al
    Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias.
    Blood. 2022;140:253-261.
    PubMed     Abstract available
    
    
    
56. NISS O, Detterich JA, Wood JC, Coates TD, et al
    Early initiation of disease-modifying therapy can impede or prevent diffuse myocardial fibrosis in sickle cell anemia.
    Blood. 2022 Jul 20. pii: 485971. doi: 10.1182/blood.2021015303.
    PubMed    
    
    
    
57. MCREYNOLDS LJ, Rafati M, Wang Y, Ballew BJ, et al
    Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes.
    Blood. 2022 Jul 1. pii: 485762. doi: 10.1182/blood.2022016508.
    PubMed     Abstract available
    
    
    June 2022
58. LANZKRON S, Pecker L
    Pain without gain: steroids and sickle crisis.
    Blood. 2022;139:3678-3679.
    PubMed    
    
    
    
59. THAKRAL B, Bueso-Ramos CE
    Unexpected presentation of cold agglutinin syndrome with B-acute lymphoblastic leukemia.
    Blood. 2022;139:3778.
    PubMed    
    
    
    
60. WALTER O, Cougoul P, Maquet J, Bartolucci P, et al
    Risk of vaso-occlusive episode after exposure to corticosteroids in patients with sickle cell disease.
    Blood. 2022;139:3771-3777.
    PubMed     Abstract available
    
    
    
61. KROLL MH, Rojas-Hernandez C, Yee C
    Hematologic complications of immune checkpoint inhibitors.
    Blood. 2022;139:3594-3604.
    PubMed     Abstract available
    
    
    
62. GAVRIILAKI E, de Latour RP, Risitano AM
    Advancing therapeutic complement inhibition in hematologic diseases: PNH and beyond.
    Blood. 2022;139:3571-3582.
    PubMed     Abstract available
    
    
    
63. GERBER GF, Brodsky RA
    Pegcetacoplan for paroxysmal nocturnal hemoglobinuria.
    Blood. 2022;139:3361-3365.
    PubMed     Abstract available
    
    
    
64. DOTY RT, Fan X, Young DJ, Liang J, et al
    Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis.
    Blood. 2022;139:3439-3449.
    PubMed     Abstract available
    
    
    May 2022
65. ISKANDER D, Warren AJ
    Turning up the HEAT(R3) in Diamond-Blackfan anemia.
    Blood. 2022;139:3101-3102.
    PubMed    
    
    
    
66. BODINE DM
    Anemia of inflammation is all the RAGE.
    Blood. 2022;139:3106-3107.
    PubMed    
    
    
    
67. XU JZ, Thein SL
    Revisiting anemia in sickle cell disease and finding the balance with therapeutic approaches.
    Blood. 2022;139:3030-3039.
    PubMed     Abstract available
    
    
    April 2022
68. NOVELLI EM
    Extinguishing the fire in sickle cell anemia.
    Blood. 2022;139:2578-2580.
    PubMed    
    
    
    
69. DAS NK, Jain C, Sankar A, Schwartz AJ, et al
    Modulation of the HIF2alpha-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis.
    Blood. 2022;139:2547-2552.
    PubMed     Abstract available
    
    
    
70. WHITE NJ
    What causes malaria anemia?
    Blood. 2022;139:2268-2269.
    PubMed    
    
    
    
71. MAHAMAR A, Gonzales Hurtado PA, Morrison R, Boone R, et al
    Plasma biomarkers of hemoglobin loss in Plasmodium falciparum-infected children identified by quantitative proteomics.
    Blood. 2022;139:2361-2376.
    PubMed     Abstract available
    
    
    
72. NWOGBO OV, Loghavi S
    Essential thrombocythemia complicating hemoglobin SC disease and presenting with priapism.
    Blood. 2022;139:2258.
    PubMed    
    
    
    
73. WANG M, Dingler FA, Patel KJ
    Genotoxic aldehydes in the hematopoietic system.
    Blood. 2022;139:2119-2129.
    PubMed     Abstract available
    
    
    
74. TOPFER SK, Feng R, Huang P, Ly LC, et al
    Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
    Blood. 2022;139:2107-2118.
    PubMed     Abstract available
    
    
    March 2022
75. CAZZOLA M
    RNA missplicing and ring sideroblasts in MDS.
    Blood. 2022;139:1933-1935.
    PubMed    
    
    
    
76. WOOD JC
    Pulmonary hypertension in thalassemia: a call to action.
    Blood. 2022;139:1937-1938.
    PubMed    
    
    
    
77. PINTO VM, Musallam KM, Derchi G, Graziadei G, et al
    Mortality in beta-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization.
    Blood. 2022;139:2080-2083.
    PubMed    
    
    
    
78. SCHMIDT CQ, Schrezenmeier H, Kavanagh D
    Complement and the prothrombotic state.
    Blood. 2022;139:1954-1972.
    PubMed     Abstract available
    
    
    
79. DOSUNMU-OGUNBI A, Yuan S, Reynolds M, Giordano L, et al
    SOD2 V16A amplifies vascular dysfunction in sickle cell patients by curtailing mitochondria complex IV activity.
    Blood. 2022;139:1760-1765.
    PubMed     Abstract available
    
    
    
80. MESSONNIER LA
    Mitochondrial function in sickle cell disease.
    Blood. 2022;139:1616-1617.
    PubMed    
    
    
    
81. WONTAKAL SN, Britto M, Zhang H, Han Y, et al
    RACGAP1 variants in a sporadic case of CDA III implicate the dysfunction of centralspindlin as the basis of the disease.
    Blood. 2022;139:1413-1418.
    PubMed    
    
    
    February 2022
82. REES DC, Kilinc Y, Unal S, Dampier CD, et al
    A randomized, placebo-controlled, double-blind trial of canakinumab in children and young adults with sickle cell anemia.
    Blood. 2022 Feb 28. pii: 484189. doi: 10.1182/blood.2021013674.
    PubMed     Abstract available
    
    
    
83. O'DONOHUE MF, Da Costa LM, Lezzerini M, Unal S, et al
    HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia.
    Blood. 2022 Feb 25. pii: 484180. doi: 10.1182/blood.2021011846.
    PubMed     Abstract available
    
    
    
84. GALLAGHER PG
    Anemia in the pediatric patient.
    Blood. 2022 Feb 25. pii: 484178. doi: 10.1182/blood.2020006479.
    PubMed     Abstract available
    
    
    
85. MENON AV, Liu J, Tsai HP, Zeng L, et al
    Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease.
    Blood. 2022;139:936-941.
    PubMed     Abstract available
    
    
    January 2022
86. NEUMANN NM, Wen KW
    Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts, thrombocytosis, and mutated JAK2/SF3B1 without anemia.
    Blood. 2022;139:466.
    PubMed    
    
    
    
87. RAO VK
    Evans syndrome: pathology and genomic hubris.
    Blood. 2022;139:312-313.
    PubMed    
    
    
    
88. KUMAR D, Prince C, Bennett CM, Briones M, et al
    T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome.
    Blood. 2022;139:369-383.
    PubMed     Abstract available
    
    
    
89. DULMOVITS BM, Tang Y, Papoin J, He M, et al
    HMGB1-Mediated Restriction of EPO Signaling Contributes to Anemia of Inflammation.
    Blood. 2022 Jan 18. pii: 483547. doi: 10.1182/blood.2021012048.
    PubMed     Abstract available
    
    
    
90. LUDWIG L, Lareau CA, Bao EL, Liu N, et al
    A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1.
    Blood. 2022 Jan 14. pii: 483530. doi: 10.1182/blood.2021013753.
    PubMed     Abstract available
    
    
    
91. DHUNPUTH C, Ducassou S, Fernandes H, Picard C, et al
    Abatacept is useful in autoimmune cytopenia with immunopathologic manifestations caused by CTLA-4 defects.
    Blood. 2022;139:300-304.
    PubMed    
    
    
    December 2021
92. PAGLIUCA S, Gurnari C, Awada H, Kishtagari A, et al
    The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders.
    Blood. 2021;138:2781-2798.
    PubMed     Abstract available
    
    
    
93. TANG A, Strat AN, Rahman M, Zhang H, et al
    Murine bone marrow mesenchymal stromal cells have reduced hematopoietic maintenance ability in sickle cell disease.
    Blood. 2021;138:2570-2582.
    PubMed     Abstract available
    
    
    
94. PECKER L, Hussain S, Mahesh J, Varadhan R, et al
    Diminished ovarian reserve in young women with sickle cell anemia.
    Blood. 2021 Dec 5. pii: 482897. doi: 10.1182/blood.2021012756.
    PubMed    
    
    
    
95. MARTIN MERINERO H, Zhang Y, Arjona E, Del Angel G, et al
    Functional characterization of 105 factor H variants associated with aHUS: lessons for variant classification.
    Blood. 2021;138:2185-2201.
    PubMed     Abstract available
    
    
    November 2021
96. DUCHEMANN B, Lazarian G
    Post-SARS-CoV-2 vaccination acute hemolysis in an older man: don't forget to look at the blood smear.
    Blood. 2021;138:2153.
    PubMed    
    
    
    
97. PINCEZ T, Lee SSK, Ilboudo Y, Preuss M, et al
    Clonal hematopoiesis in sickle cell disease.
    Blood. 2021;138:2148-2152.
    PubMed    
    
    
    
98. LUZZATTO L
    Control of hemolysis in patients with PNH.
    Blood. 2021;138:1908-1910.
    PubMed    
    
    
    
99. KULASEKARARAJ AG, Risitano AM, Maciejewski JP, Notaro R, et al
    Phase 2 study of danicopan in patients with paroxysmal nocturnal hemoglobinuria with an inadequate response to eculizumab.
    Blood. 2021;138:1928-1938.
    PubMed     Abstract available
    
    
    
100. EL SISSY C, Saldman A, Zanetta G, Martins PV, et al
     COVID-19 as a potential trigger of complement-mediated atypical HUS.
     Blood. 2021;138:1777-1782.
     PubMed    
     
     
     
101. FENG Y, Feng W
     Numerous ring sideroblasts in chronic neutrophilic leukemia.
     Blood. 2021;138:1783.
     PubMed    
     
     
     
102. ZAIMOKU Y, Patel BA, Adams SD, Shalhoub RN, et al
     HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia.
     Blood. 2021 Nov 1. pii: 477734. doi: 10.1182/blood.2021012895.
     PubMed     Abstract available
     
     
     September 2021
103. HENRY ER, Metaferia B, Li Q, Harper J, et al
     Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
     Blood. 2021;138:1172-1181.
     PubMed     Abstract available
     
     
     
104. LIU Y, Pal M, Bao W, Shi PA, et al
     Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease.
     Blood. 2021;138:1162-1171.
     PubMed     Abstract available
     
     
     
105. IRELAND RM, Rees DC
     Two brothers with a novel KLF1 mutation.
     Blood. 2021;138:1087.
     PubMed    
     
     
     
106. ABRAHAM AA, Tisdale JF
     Gene therapy for sickle cell disease: moving from the bench to the bedside.
     Blood. 2021;138:932-941.
     PubMed     Abstract available
     
     
     
107. BOLLARD CM
     Introduction to a review series on gene therapy and gene editing for sickle cell disease and hemophilia.
     Blood. 2021;138:913.
     PubMed    
     
     
     
108. PATEL BA, Groarke EM, Lotter J, Shalhoub RN, et al
     Long-term outcomes in severe aplastic anemia patients treated with immunosuppression and eltrombopag: a phase 2 study.
     Blood. 2021 Sep 15. pii: 476916. doi: 10.1182/blood.2021012130.
     PubMed     Abstract available
     
     
     August 2021
109. COCHRAN T, Li W
     Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation.
     Blood. 2021;138:738.
     PubMed    
     
     
     
110. XU Z, Mueller R
     Myelodysplastic pure red cell aplasia.
     Blood. 2021;138:500.
     PubMed    
     
     
     July 2021
111. JALINK M, Berentsen S, Castillo J, Treon SPP, et al
     Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome.
     Blood. 2021 Jul 22. pii: 476451. doi: 10.1182/blood.2021012039.
     PubMed    
     
     
     
112. RICE L, Schwartz MR
     Sickle cell hepatopathy with spur cell anemia.
     Blood. 2021;138:283.
     PubMed    
     
     
     
113. GERBER GF, Yuan X, Yu J, Cher BAY, et al
     COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria.
     Blood. 2021;137:3670-3673.
     PubMed    
     
     
     June 2021
114. MORENO C
     Autoimmune cytopenia and CLL ride together.
     Blood. 2021;137:3464-3465.
     PubMed    
     
     
     
115. MARTIN MERINERO H, Subias M, Pereda A, Gomez-Rubio E, et al
     Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases.
     Blood. 2021;137:3484-3494.
     PubMed     Abstract available
     
     
     
116. REJESKI K, Perez Perez A, Sesques P, Hoster E, et al
     CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma.
     Blood. 2021 Jun 24. pii: 476241. doi: 10.1182/blood.2020010543.
     PubMed     Abstract available
     
     
     
117. PSATHA N, Georgakopoulou A, Li C, Nandakumar V, et al
     Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo.
     Blood. 2021 Jun 4. pii: 476068. doi: 10.1182/blood.2020010020.
     PubMed     Abstract available
     
     
     
118. RARICK KR, Pritchard KA
     The sickle erythrocyte yields another DAMP.
     Blood. 2021;137:3010-3011.
     PubMed    
     
     
     
119. JONES RJ, DeBaun MR
     Leukemia after gene therapy for sickle cell disease: insertional mutagenesis, busulfan, both or neither.
     Blood. 2021 Jun 3. pii: 476065. doi: 10.1182/blood.2021011488.
     PubMed     Abstract available
     
     
     
120. TUMBURU L, Ghosh-Choudhary S, Seifuddin FT, Barbu EA, et al
     Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease.
     Blood. 2021;137:3116-3126.
     PubMed     Abstract available
     
     
     May 2021
121. RAB MAE, Bos J, van Oirschot BA, van Straaten S, et al
     Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy.
     Blood. 2021;137:2997-3001.
     PubMed    
     
     
     
122. MANWANI D
     P-selectin and sickle cell disease: a balancing act.
     Blood. 2021;137:2573-2574.
     PubMed    
     
     
     
123. VATS R, Kaminski TW, Ju EM, Brozska T, et al
     P-selectin deficiency promotes liver senescence in sickle cell disease mice.
     Blood. 2021;137:2676-2680.
     PubMed     Abstract available
     
     
     
124. BRODSKY RA
     Eculizumab and aHUS: to stop or not.
     Blood. 2021;137:2419-2420.
     PubMed    
     
     
     
125. FAKHOURI F, Fila M, Hummel A, Ribes D, et al
     Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study.
     Blood. 2021;137:2438-2449.
     PubMed     Abstract available
     
     
     April 2021
126. CERCAMONDI CI, Stoffel N, Moretti D, Zoller T, et al
     Iron homeostasis during anemia of inflammation: a prospective study in patients with tuberculosis.
     Blood. 2021 Apr 19. pii: 475787. doi: 10.1182/blood.2020010562.
     PubMed     Abstract available
     
     
     
127. SHAH N
     ELIPSIS: developing tools to better understand VOC in SCD.
     Blood. 2021;137:1987-1988.
     PubMed    
     
     
     
128. GURNARI C, Maciejewski JP
     How I manage acquired pure red cell aplasia in adults.
     Blood. 2021;137:2001-2009.
     PubMed     Abstract available
     
     
     
129. PITTMAN DD, Hines PC, Beidler D, Rybin D, et al
     Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers.
     Blood. 2021;137:2010-2020.
     PubMed     Abstract available
     
     
     
130. TURNIS ME, Kaminska E, Smith KH, Kartchner BJ, et al
     Requirement for antiapoptotic MCL-1 during early erythropoiesis.
     Blood. 2021;137:1945-1958.
     PubMed     Abstract available
     
     
     March 2021
131. GONG Y, Zhang X, Zhang Q, Zhang Y, et al
     A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the gamma-globin gene in beta-thalassemia.
     Blood. 2021;137:1652-1657.
     PubMed     Abstract available
     
     
     
132. ZHU C, Lian Y, Wang C, Wu P, et al
     Single-cell transcriptomics dissects hematopoietic cell destruction and T cell engagement in aplastic anemia.
     Blood. 2021 Mar 24. pii: 475591. doi: 10.1182/blood.2020008966.
     PubMed     Abstract available
     
     
     
133. HOSOKAWA K, Mizumaki H, Yoroidaka T, Maruyama H, et al
     HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia.
     Blood. 2021 Mar 22. pii: 475586. doi: 10.1182/blood.2020010586.
     PubMed    
     
     
     
134. BRUGNARA C
     Less (Fe) is more (Hb) in SCA.
     Blood. 2021;137:1446-1447.
     PubMed    
     
     
     
135. ANSARI J, Senchenkova EY, Vital SA, Al-Yafeai Z, et al
     Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease.
     Blood. 2021;137:1538-1549.
     PubMed     Abstract available
     
     
     
136. ELDAR D, Ganzel C
     Erythrophagocytosis in a young adult with mycoplasma pneumonia-induced paroxysmal cold hemoglobinuria.
     Blood. 2021;137:1432.
     PubMed    
     
     
     
137. BERENTSEN S
     How I treat cold agglutinin disease.
     Blood. 2021;137:1295-1303.
     PubMed     Abstract available
     
     
     
138. BRODSKY RA
     How I treat paroxysmal nocturnal hemoglobinuria.
     Blood. 2021;137:1304-1309.
     PubMed     Abstract available
     
     
     
139. ZHABYEYEV P, Oudit GY
     Sickle cell disease, interleukin-18, and arrhythmias.
     Blood. 2021;137:1138-1139.
     PubMed    
     
     
     
140. GUPTA A, Fei YD, Kim TY, Xie A, et al
     IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.
     Blood. 2021;137:1208-1218.
     PubMed     Abstract available
     
     
     February 2021
141. WACHTER F, Archer NM
     Autoimmune hemolytic anemia complicated by parvovirus infection.
     Blood. 2021;137:1130.
     PubMed    
     
     
     
142. GU Y, Yang R, Yang Y, Zhao Y, et al
     IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.
     Blood. 2021;137:945-958.
     PubMed     Abstract available
     
     
     
143. AL-SAMKARI H
     Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
     Blood. 2021;137:888-895.
     PubMed     Abstract available
     
     
     
144. WARE RE, Dertinger SD
     There's safety in numbers.
     Blood. 2021;137:729-731.
     PubMed    
     
     
     
145. REES DC
     Hydroxyurea: coming to conclusions on safety.
     Blood. 2021;137:728-729.
     PubMed    
     
     
     
146. GILLE AS, Pondarre C, Dalle JH, Bernaudin F, et al
     Hydroxyurea does not affect the spermatogonial pool in prepubertal patients with sickle cell disease.
     Blood. 2021;137:856-859.
     PubMed    
     
     
     
147. JOSEPH L, Jean C, Manceau S, Chalas C, et al
     Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
     Blood. 2021;137:826-829.
     PubMed     Abstract available
     
     
     
148. SHENG Y, Ma R, Yu C, Wu Q, et al
     Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
     Blood. 2021;137:610-623.
     PubMed     Abstract available
     
     
     January 2021
149. BADAT M, Davies JOJ, Fisher CA, Downes DJ, et al
     A remarkable case of HbH disease illustrates the relative contributions of the alpha-globin enhancers to gene expression.
     Blood. 2021;137:572-575.
     PubMed    
     
     
     
150. DEANS AJ
     Fanconi anemia, put to sleep.
     Blood. 2021;137:286-288.
     PubMed    
     
     
     
151. THOMAS M, Scully M
     How I Treat Microangiopathic Hemolytic Anemia in Patients with Cancer.
     Blood. 2021 Jan 21. pii: 475029. doi: 10.1182/blood.2019003810.
     PubMed     Abstract available
     
     
     
152. CAZZOLA M
     Introduction to a How I Treat Series on Acquired Hemolytic Anemia.
     Blood. 2021 Jan 21. pii: 475027. doi: 10.1182/blood.2020009747.
     PubMed    
     
     
     
153. BARCELLINI W, Fattizzo B
     How I treat warm autoimmune hemolytic anemia.
     Blood. 2021 Jan 21. pii: 475030. doi: 10.1182/blood.2019003808.
     PubMed     Abstract available
     
     
     
154. PIRENNE F
     Heme control to major B (cell): are you listening?
     Blood. 2021;137:153-154.
     PubMed    
     
     
     
155. PAL M, Bao W, Wang R, Liu Y, et al
     Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease.
     Blood. 2021;137:269-280.
     PubMed     Abstract available
     
     
     
156. MU A, Hira A, Niwa A, Osawa M, et al
     Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
     Blood. 2021 Jan 12. pii: 474923. doi: 10.1182/blood.2020009111.
     PubMed     Abstract available
     
     
     
157. SALIB C, Hussein S
     A case of hairy cell leukemia with markedly hypocellular marrow mimicking aplastic anemia.
     Blood. 2021;137:142.
     PubMed    
     
     
     December 2020
158. SICA M, Pellecchia A, De Angioletti M, Caocci G, et al
     Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH.
     Blood. 2020;136:3082-3085.
     PubMed    
     
     
     
159. MARIANI R, Liu H
     Severe transient pancytopenia with dyserythropoiesis and dysmegakaryopoiesis in COVID-19-associated MIS-C.
     Blood. 2020;136:2964.
     PubMed    
     
     
     
160. ARORA S, Ganapathi KA
     Prominent pseudo-Gaucher cells in a patient with beta-thalassemia intermedia and plasma cell myeloma.
     Blood. 2020;136:2839.
     PubMed    
     
     
     
161. PARROW NL, Violet PC, Ajit George N, Ali F, et al
     Dietary Iron Restriction Improves Markers of Disease Severity in Murine Sickle Cell Anemia.
     Blood. 2020 Dec 8. pii: 474426. doi: 10.1182/blood.2020006919.
     PubMed    
     
     
     November 2020
162. ABKOWITZ JL
     A simple Rx for congenital erythropoietic porphyria.
     Blood. 2020;136:2371-2372.
     PubMed    
     
     
     October 2020
163. DEWARRAT N, Blum S
     Heavy metal.
     Blood. 2020;136:1993.
     PubMed    
     
     
     September 2020
164. ARJONA E, Huerta A, Goicoechea de Jorge E, Rodriguez de Cordoba S, et al
     Familial risk of developing atypical hemolytic-uremic syndrome.
     Blood. 2020;136:1558-1561.
     PubMed    
     
     
     
165. KIM-SHAPIRO DB, Gladwin MT
     Arginine for mitochondrial oxidative enzymopathy.
     Blood. 2020;136:1376-1378.
     PubMed    
     
     
     
166. MORRIS CR, Brown LAS, Reynolds M, Dampier CD, et al
     Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain.
     Blood. 2020;136:1402-1406.
     PubMed     Abstract available
     
     
     
167. LUZZATTO L, Ally M, Notaro R
     Glucose-6-phosphate dehydrogenase deficiency.
     Blood. 2020;136:1225-1240.
     PubMed     Abstract available
     
     
     
168. SCHELL B, Fenneteau O
     Brandalise syndrome: a rare inclusion cell disease.
     Blood. 2020;136:1373.
     PubMed    
     
     
     
169. RISINGER M, Kalfa TA
     Red cell membrane disorders: structure meets function.
     Blood. 2020;136:1250-1261.
     PubMed     Abstract available
     
     
     
170. CAZZOLA M
     Introduction to a review series on inherited anemias.
     Blood. 2020;136:1215-1216.
     PubMed    
     
     
     
171. IOLASCON A, Andolfo I, Russo R
     Congenital dyserythropoietic anemias.
     Blood. 2020;136:1274-1283.
     PubMed     Abstract available
     
     
     
172. GRACE RF, Barcellini W
     Management of pyruvate kinase deficiency in children and adults.
     Blood. 2020;136:1241-1249.
     PubMed     Abstract available
     
     
     
173. BROUSSE V, Connes P
     Vasomotor hyperresponsiveness in SCD.
     Blood. 2020;136:1120-1121.
     PubMed    
     
     
     
174. VELUSWAMY S, Shah P, Khaleel M, Thuptimdang W, et al
     Progressive vasoconstriction with sequential thermal stimulation indicates vascular dysautonomia in sickle cell disease.
     Blood. 2020;136:1191-1200.
     PubMed     Abstract available
     
     
     August 2020
175. VOIT RA, Grace RF
     Pyruvate kinase deficiency in a newborn with extramedullary hematopoiesis in the skin.
     Blood. 2020;136:770.
     PubMed    
     
     
     July 2020
176. CARLESSO N
     Targeting the bone marrow niche in hemoglobinopathies.
     Blood. 2020;136:529-531.
     PubMed    
     
     
     
177. BRAZAUSKAS R, Scigliuolo GM, Wang HL, Cappelli B, et al
     Risk score to predict event-free survival after hematopoietic cell transplant for sickle cell disease.
     Blood. 2020;136:623-626.
     PubMed     Abstract available
     
     
     
178. ROTH A
     Do temperature and time matter in cold agglutinin disease?
     Blood. 2020;136:380-381.
     PubMed    
     
     
     
179. BERENTSEN S, Barcellini W, D'Sa S, Randen U, et al
     Cold agglutinin disease revisited: a multinational, observational study of 232 patients.
     Blood. 2020;136:480-488.
     PubMed     Abstract available
     
     
     
180. KATO GJ
     Sickle particulars of microparticles.
     Blood. 2020;136:154-155.
     PubMed    
     
     
     
181. GARNIER Y, Ferdinand S, Garnier M, Cita KC, et al
     Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties.
     Blood. 2020;136:247-256.
     PubMed     Abstract available
     
     
     
182. EVANS EL, Povstyan OV, De Vecchis D, Macrae F, et al
     RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis.
     Blood. 2020;136:140-144.
     PubMed    
     
     
     June 2020
183. KHAN R, Menard M, Jen CC, Chen X, et al
     Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP.
     Blood. 2020;135:2420-2424.
     PubMed     Abstract available
     
     
     
184. CHEN BY, Song J, Hu CL, Chen SB, et al
     SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
     Blood. 2020;135:2271-2285.
     PubMed     Abstract available
     
     
     
185. HUANG P, Peslak SA, Lan X, Khandros E, et al
     The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression.
     Blood. 2020;135:2121-2132.
     PubMed     Abstract available
     
     
     
186. WALTERS MC
     Sickle marrow: double, double toil and trouble.
     Blood. 2020;135:2017-2018.
     PubMed    
     
     
     
187. PARK SY, Matte A, Jung Y, Ryu J, et al
     Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion.
     Blood. 2020;135:2071-2084.
     PubMed     Abstract available
     
     
     May 2020
188. KHANDROS E, Huang P, Peslak SA, Sharma M, et al
     Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
     Blood. 2020;135:1957-1968.
     PubMed     Abstract available
     
     
     
189. GORDEUK VR
     Sickle cell vaso-occlusion: the clot thickens.
     Blood. 2020;135:1726-1727.
     PubMed    
     
     
     
190. SPARKENBAUGH EM, Chen C, Brzoska T, Nguyen J, et al
     Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease.
     Blood. 2020;135:1783-1787.
     PubMed     Abstract available
     
     
     April 2020
191. SCHINDLER D, Kalb R
     Disease and mutation: correlations coming to fruition.
     Blood. 2020;135:1514-1515.
     PubMed    
     
     
     
192. APRILE A, Gulino A, Storto M, Villa I, et al
     Hematopoietic stem cell function in beta-thalassemia is impaired and is rescued by targeting the bone marrow niche.
     Blood. 2020 Apr 28. pii: 454666. doi: 10.1182/blood.2019002721.
     PubMed     Abstract available
     
     
     
193. GHANNAM JY, Xu X, Maric I, Dillon L, et al
     Baseline TP53 mutations in adults with SCD developing myeloid malignancy following hematopoietic cell transplantation.
     Blood. 2020;135:1185-1188.
     PubMed    
     
     
     March 2020
194. SARAF SL
     Heme A1M'ed at the kidney in sickle cell disease.
     Blood. 2020;135:979-981.
     PubMed    
     
     
     
195. OFORI-ACQUAH SF, Hazra R, Orikogbo OO, Crosby D, et al
     Hemopexin deficiency promotes acute kidney injury in sickle cell disease.
     Blood. 2020;135:1044-1048.
     PubMed     Abstract available
     
     
     
196. BRODSKY RA
     A complementary new drug for PNH.
     Blood. 2020;135:884-885.
     PubMed    
     
     
     
197. ROTH A, Nishimura JI, Nagy Z, Gaal-Weisinger J, et al
     The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria.
     Blood. 2020;135:912-920.
     PubMed     Abstract available
     
     

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