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Articles published in Haematologica

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    April 2019
  1. ROGERS ZR, Nakano TA, Olson TS, Bertuch AA, et al
    Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study.
    Haematologica. 2019 Apr 4. pii: haematol.2018.206540.
    PubMed     Text format     Abstract available

    March 2019
  2. CURSINO-SANTOS JR, Singh M, Senaldi E, Manwani D, et al
    Altered parasite life-cycle processes characterize Babesia divergens infection in human sickle cell anemia.
    Haematologica. 2019 Mar 28. pii: haematol.2018.214304.
    PubMed     Text format     Abstract available

  3. FATTIZZO B, Kulasekararaj AG, Hill A, Benson-Quarm N, et al
    Clinical and morphologic predictors of outcome in older aplastic anemia patients treated with eltrombopag.
    Haematologica. 2019 Mar 19. pii: haematol.2019.216374.
    PubMed     Text format    

  4. ELBADRY MI, Mizumaki H, Hosokawa K, Espinoza JL, et al
    Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia.
    Haematologica. 2019 Mar 19. pii: haematol.2018.210856.
    PubMed     Text format    

  5. ZAHR RS, Rampersaud E, Kang G, Weiss MJ, et al
    Children with sickle cell anemia and APOL1 genetic variants develop albuminuria early in life.
    Haematologica. 2019 Mar 19. pii: haematol.2018.212779.
    PubMed     Text format     Abstract available

  6. VARRICCHIO L, Planutis A, Manwani D, Jaffray J, et al
    Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient.
    Haematologica. 2019 Mar 14. pii: haematol.2018.209858.
    PubMed     Text format     Abstract available

  7. GIRELLI D, Busti F
    Anemia and adverse outcomes in the elderly: a detrimental inflammatory loop?
    Haematologica. 2019;104:417-419.
    PubMed     Text format    

    February 2019
  8. MORI M, Hira A, Yoshida K, Muramatsu H, et al
    Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients.
    Haematologica. 2019 Feb 21. pii: haematol.2018.207241.
    PubMed     Text format     Abstract available

    Antithymocyte globulin and cyclosporin: standard of care also for older patients with aplastic anemia.
    Haematologica. 2019;104:215-216.
    PubMed     Text format    

    January 2019
  10. MIANO M, Eikema DJ, Aljurf M, Van't Veer PJ, et al
    Stem cell transplantation for congenital dyserythropoietic anemia. An analysis from the European society for blood and marrow transplantation.
    Haematologica. 2019 Jan 24. pii: haematol.2018.206623.
    PubMed     Text format    

  11. STOFFEL NU, Lazrak M, Bellitir S, El Mir N, et al
    The opposing effects of acute inflammation and iron deficiency anemia on serum hepcidin and iron absorption in young women.
    Haematologica. 2019 Jan 10. pii: haematol.2018.208645.
    PubMed     Text format     Abstract available

    October 2018
  12. CAPPELLINI MD, Porter J, Origa R, Forni GL, et al
    Sotatercept, a novel transforming growth factor beta ligand trap, improves anemia in beta-thalassemia: a phase 2, open-label, dose-finding study.
    Haematologica. 2018 Oct 18. pii: haematol.2018.198887.
    PubMed     Text format     Abstract available

  13. WOUTERS HJCM, van der Klauw MM, de Witte T, Stauder R, et al
    Association of anemia with health-related quality of life and survival: a large population-based cohort study.
    Haematologica. 2018 Oct 11. pii: haematol.2018.195552.
    PubMed     Text format     Abstract available

  14. PARK S, Kosmider O, Maloisel F, Drenou B, et al
    Dyserythropoiesis evaluated by RED score and hepcidin/ferritin levels predicts response to erythropoietin in lower risk myelodysplastic syndromes.
    Haematologica. 2018 Oct 4. pii: haematol.2018.203158.
    PubMed     Text format     Abstract available

    September 2018
  15. ARTUSO I, Pettinato M, Nai A, Pagani A, et al
    Transient decrease of serum iron after acute erythropoietin treatment contributes to hepcidin inhibition by ERFE in mice.
    Haematologica. 2018 Sep 28. pii: haematol.2018.199810.
    PubMed     Text format    

  16. CONTEJEAN A, Resche-Rigon M, Tamburini J, Alcantara M, et al
    Aplastic anemia in the elderly: a nationwide survey on behalf of the French Reference Center for Aplastic Anemia.
    Haematologica. 2018 Sep 27. pii: haematol.2018.198440.
    PubMed     Text format     Abstract available

  17. JONGMANS MCJ, Diets IJ, Quarello P, Garelli E, et al
    Somatic reversion events point towards RPL4 as a novel disease gene in a condition resembling Diamond-Blackfan Anemia.
    Haematologica. 2018 Sep 13. pii: haematol.2018.200683.
    PubMed     Text format    

    July 2018
  18. RILEY LG, Heeney MM, Rudinger-Thirion J, Frugier M, et al
    The phenotypic spectrum of germline YARS2 variants: from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2.
    Haematologica. 2018 Jul 19. pii: haematol.2017.182659.
    PubMed     Text format     Abstract available

  19. BERHE S, Heeney MM, Campagna DR, Thompson JF, et al
    Recurrent heteroplasmy for the MT-ATP6 p.Ser148Asn (m.8969G>A) mutation in patients with syndromic congenital sideroblastic anemia of variable clinical severity.
    Haematologica. 2018 Jul 13. pii: haematol.2018.199109.
    PubMed     Text format    

  20. ADAIR JE, Chandrasekaran D, Sghia-Hughes G, Haworth KG, et al
    Novel lineage depletion preserves autologous blood stem cells for gene therapy of Fanconi anemia complementation group A.
    Haematologica. 2018 Jul 5. pii: haematol.2018.194571.
    PubMed     Text format     Abstract available

  21. SMITH F, Hopton S, Dallabona C, Gilberti M, et al
    Sideroblastic anemia with myopathy secondary to novel, pathogenic missense variants in the YARS2 gene.
    Haematologica. 2018 Jul 5. pii: haematol.2018.194464.
    PubMed     Text format    

    Complication free survival long-term after hemopoietic cell transplantation in thalassemia.
    Haematologica. 2018;103:1094-1096.
    PubMed     Text format    

    May 2018
  23. MCCABE A, Smith JNP, Costello A, Maloney J, et al
    Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression.
    Haematologica. 2018 May 17. pii: haematol.2018.189449.
    PubMed     Text format     Abstract available

    (Auto-)immune signature in aplastic anemia.
    Haematologica. 2018;103:747-749.
    PubMed     Text format    

  25. HSIEH MM, Tisdale JF
    Hematopoietic stem cell mobilization with plerixafor in sickle cell disease.
    Haematologica. 2018;103:749-750.
    PubMed     Text format    

    April 2018
  26. GIUDICE V, Banaszak LG, Gutierrez-Rodrigues F, Kajigaya S, et al
    Diagnostic and prognostic roles of circulating exosomal microRNAs in acquired aplastic anemia and myelodysplastic syndromes.
    Haematologica. 2018 Apr 19. pii: haematol.2017.182824.
    PubMed     Text format     Abstract available

  27. MADEDDU C, Gramignano G, Kotsonis P, Coghe F, et al
    Microenvironmental M1 tumor-associated macrophage polarization influences cancer-related anemia in advanced ovarian cancer: key role of Interleukin-6.
    Haematologica. 2018 Apr 19. pii: haematol.2018.191551.
    PubMed     Text format    

    March 2018
  28. WLODARSKI MW, Da Costa L, O'Donohue MF, Gastou M, et al
    Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia.
    Haematologica. 2018 Mar 29. pii: haematol.2017.177980.
    PubMed     Text format     Abstract available

  29. TEWARI S, Renney G, Brewin J, Gardner K, et al
    Proteomic analysis of plasma from children with sickle cell anemia and silent cerebral infarction.
    Haematologica. 2018 Mar 15. pii: haematol.2018.187815.
    PubMed     Text format     Abstract available

  30. GRIFFIN M, Kulasekararaj A, Gandhi S, Munir T, et al
    Concurrent treatment of aplastic anemia/Paroxysmal Nocturnal Hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience.
    Haematologica. 2018 Mar 15. pii: haematol.2017.183046.
    PubMed     Text format    

  31. VALLET N, de Fontbrune FS, Loschi M, Desmier D, et al
    Hematopoietic stem cell transplantation for patients with paroxysmal nocturnal hemoglobinuria previously treated with eculizumab: a retrospective study of 21 patients from SFGM-TC centers.
    Haematologica. 2018;103:e103-e105.
    PubMed     Text format    

  32. ANDOLFO I, Manna F, De Rosa G, Rosato BE, et al
    PIEZO1-R1864H rare variant accounts for a genetic phenotype-modifier role in dehydrated hereditary stomatocytosis.
    Haematologica. 2018;103:e94-e97.
    PubMed     Text format    

    February 2018
  33. GIUDICE V, Feng X, Lin Z, Hu W, et al
    Deep sequencing and flow cytometric characterization of expanded effector memory CD8+CD57+ T cells frequently reveals T-cell receptor Vbeta oligoclonality and CDR3 homology in acquired aplastic anemia.
    Haematologica. 2018 Feb 1. pii: haematol.2017.176701.
    PubMed     Text format     Abstract available

  34. HATTA S, Fujiwara T, Yamamoto T, Saito K, et al
    A defined culture method enabling the establishment of ring sideroblasts from induced pluripotent cells of X-linked sideroblastic anemia.
    Haematologica. 2018 Feb 1. pii: haematol.2017.179770.
    PubMed     Text format    

  35. HANUDEL MR, Rappaport M, Chua K, Gabayan V, et al
    Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease.
    Haematologica. 2018 Feb 1. pii: haematol.2017.181743.
    PubMed     Text format    

  36. VAN STRAATEN S, Bierings M, Bianchi P, Akiyoshi K, et al
    Worldwide study of hematopoietic allogeneic stem cell transplantation in pyruvate kinase deficiency.
    Haematologica. 2018;103:e82-e86.
    PubMed     Text format    

  37. BALASUBRAMANIAN SK, Sadaps M, Thota S, Aly M, et al
    Rational management approach to pure red cell aplasia.
    Haematologica. 2018;103:221-230.
    PubMed     Text format     Abstract available

  38. CASU C, Presti VL, Oikonomidou PR, Melchiori L, et al
    Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of beta-thalassemia intermedia and major.
    Haematologica. 2018;103:e46-e49.
    PubMed     Text format    

    December 2017
  39. BOTTEGA R, Nicchia E, Cappelli E, Ravera S, et al
    Hypomorphic FANCA mutations correlate with mild mitochondrial and clinical phenotype in Fanconi anemia.
    Haematologica. 2017 Dec 21. pii: haematol.2017.176131.
    PubMed     Text format     Abstract available

  40. PASQUIER F, Marty C, Balligand T, Verdier F, et al
    New pathogenic mechanisms induced by germline erythropoietin receptor mutations in primary erythrocytosis.
    Haematologica. 2017 Dec 21. pii: haematol.2017.176370.
    PubMed     Text format     Abstract available

  41. FANG X, Shen F, Lechauve C, Xu P, et al
    miR-144/451 represses the LKB1/AMPK/mTOR pathway to promote red cell precursor survival during recovery from acute anemia.
    Haematologica. 2017 Dec 21. pii: haematol.2017.177394.
    PubMed     Text format     Abstract available

    November 2017
  42. ANAMPA J, Haque T, Murakhovskaya I, Wang Y, et al
    Macrocytosis and dysplastic anemia is associated with the Cyclin-Dependent Kinase 4/6 inhibitor palbociclib in metastatic breast cancer.
    Haematologica. 2017 Nov 30. pii: haematol.2017.181941.
    PubMed     Text format    

  43. LENGLINE E, Drenou B, Peterlin P, Tournilhac O, et al
    Nationwide survey on the use of eltrombopag in patients with severe aplastic anemia: a report on behalf of the French reference center for aplastic anemia.
    Haematologica. 2017 Nov 23. pii: haematol.2017.176339.
    PubMed     Text format     Abstract available

  44. PENKERT RR, Hurwitz JL, Thomas P, Rosch J, et al
    Inflammatory molecule reduction with hydroxyurea therapy in children with sickle cell anemia.
    Haematologica. 2017 Nov 16. pii: haematol.2017.177360.
    PubMed     Text format    

    October 2017
  45. BALAIAN E, Wobus M, Weidner H, Baschant U, et al
    Erythropoietin inhibits osteoblast function in myelodysplastic syndromes via the canonical Wnt pathway.
    Haematologica. 2017 Oct 27. pii: haematol.2017.172726.
    PubMed     Text format     Abstract available

  46. CHADEBECH P, Loustau V, Janvier D, Languille L, et al
    Clinical severity in adult warm autoimmune hemolytic anemia and its relationship to antibody specificity.
    Haematologica. 2017 Oct 12. pii: haematol.2017.175976.
    PubMed     Text format     Abstract available

  47. CLUZEAU T, McGraw KL, Irvine B, Masala E, et al
    Pro-inflammatory proteins S100A9 and TNFalpha suppress erythropoietin elaboration in myelodysplastic syndromes.
    Haematologica. 2017 Oct 5. pii: haematol.2016.158857.
    PubMed     Text format     Abstract available

    September 2017
  48. VENUGOPAL P, Moore S, Lawrence DM, George AJ, et al
    Self-reverting mutations partially correct the blood phenotype in a Diamond Blackfan Anemia patient.
    Haematologica. 2017 Sep 29. pii: haematol.2017.166678.
    PubMed     Text format    

    August 2017
  49. CLINKENBEARD EL, Hanudel MR, Stayrook KR, Appaiah HN, et al
    Erythropoietin stimulates murine and human Fibroblast growth factor-23, revealing novel roles for bone and bone marrow.
    Haematologica. 2017 Aug 17. pii: haematol.2017.167882.
    PubMed     Text format    

    July 2017
  50. VAHT K, Goransson M, Carlson K, Isaksson C, et al
    Incidence and outcome of acquired aplastic anemia-real-world data from patients diagnosed in Sweden from 2000-2011.
    Haematologica. 2017 Jul 27. pii: haematol.2017.169862.
    PubMed     Text format     Abstract available

  51. VAN DER HEM JG, de Wreede LC, Brand A, Veelken H, et al
    Long-term risk of cancer development in adult patients with idiopathic aplastic anemia after treatment with anti-thymocyte globulin.
    Haematologica. 2017 Jul 13. pii: haematol.2017.171215.
    PubMed     Text format    

    Antithymocyte globulin and transplants for aplastic anemia.
    Haematologica. 2017;102:1137-1138.
    PubMed     Text format    

    June 2017
  53. OTTO JM, Plumb JOM, Clissold E, Kumar S, et al
    Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia.
    Haematologica. 2017 Jun 8. pii: haematol.2017.169680.
    PubMed     Text format     Abstract available

  54. RAFII H, Bernaudin F, Rouard H, Vanneaux V, et al
    Family cord blood banking for sickle cell disease: a twenty-year experience in two dedicated public cord blood banks.
    Haematologica. 2017;102:976-983.
    PubMed     Text format     Abstract available

  55. URAS IZ, Scheicher RM, Kollmann K, Glosmann M, et al
    Cdk6 contributes to cytoskeletal stability in erythroid cells.
    Haematologica. 2017;102:995-1005.
    PubMed     Text format     Abstract available

    May 2017
  56. RUSSO R, Andolfo I, Gambale A, De Rosa G, et al
    GATA1 erythroid-specific regulation of SEC23B expression and its implication in the pathogenesis of Congenital Dyserythropoietic Anemia type II.
    Haematologica. 2017 May 26. pii: haematol.2016.162966.
    PubMed     Text format    

    April 2017
  57. MAITRA P, Caughey M, Robinson L, Desai PC, et al
    Risk factors for mortality in adult patients with sickle cell disease: a meta-analysis of studies in North America and Europe.
    Haematologica. 2017;102:626-636.
    PubMed     Text format     Abstract available

  58. PIEL FB, Tewari S, Brousse V, Analitis A, et al
    Associations between environmental factors and hospital admissions for sickle cell disease.
    Haematologica. 2017;102:666-675.
    PubMed     Text format     Abstract available

    March 2017
  59. ZHOU Y, He Y, Xing W, Zhang P, et al
    Abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.
    Haematologica. 2017 Mar 24. pii: haematol.2016.158717.
    PubMed     Text format     Abstract available

  60. KEKRE N, Zhang Y, Zhang MJ, Carreras J, et al
    Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia.
    Haematologica. 2017 Mar 24. pii: haematol.2017.164459.
    PubMed     Text format     Abstract available

  61. KOBAYASHI M, Kato H, Hada H, Itoh-Nakadai A, et al
    Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.
    Haematologica. 2017;102:454-465.
    PubMed     Text format     Abstract available

  62. YUAN X, Gavriilaki E, Thanassi JA, Yang G, et al
    Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.
    Haematologica. 2017;102:466-475.
    PubMed     Text format     Abstract available

    February 2017
  63. MILLOT S, Delaby C, Moulouel B, Lefebvre T, et al
    Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Gunther disease model.
    Haematologica. 2017;102:260-270.
    PubMed     Text format     Abstract available

  64. SRIVASTAVA A, Shaji RV
    Cure for thalassemia major - from allogeneic hematopoietic stem cell transplantation to gene therapy.
    Haematologica. 2017;102:214-223.
    PubMed     Text format     Abstract available

  65. KIM K, Li J, Barazia A, Tseng A, et al
    ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease.
    Haematologica. 2017;102:246-259.
    PubMed     Text format     Abstract available

  66. XIN J, Breslin P, Wei W, Li J, et al
    Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice.
    Haematologica. 2017;102:295-307.
    PubMed     Text format     Abstract available

    January 2017
  67. WEIR NA, Saiyed R, Alam S, Conrey A, et al
    Prostacyclin-analog therapy in sickle cell pulmonary hypertension.
    Haematologica. 2017 Jan 25. pii: haematol.2015.131227.
    PubMed     Text format     Abstract available

  68. BELL JB, Abedin S, Platanias LC
    Circulating microRNAs: promising biomarkers in aplastic anemia.
    Haematologica. 2017;102:1-2.
    PubMed     Text format    

    December 2016
  69. CRAZZOLARA R, Kropshofer G, Haas OA, Matthes-Martin S, et al
    Reduced-intensity conditioning and stem cell transplantation in infants with Diamond Blackfan anemia.
    Haematologica. 2016 Dec 7. pii: haematol.2016.157149.
    PubMed     Text format    

  70. IKEDA F, Yoshida K, Toki T, Uechi T, et al
    Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia.
    Haematologica. 2016 Dec 1. pii: haematol.2016.153932.
    PubMed     Text format    

    November 2016
  71. HANUDEL MR, Rappaport M, Gabayan V, Jung G, et al
    Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model.
    Haematologica. 2016 Nov 24. pii: haematol.2016.150433.
    PubMed     Text format    

    September 2016
  72. LATOUR C, Wlodarczyk MF, Jung G, Gineste A, et al
    Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.150227.
    PubMed     Text format     Abstract available

  73. HOSOKAWA K, Kajigaya S, Feng X, Desierto MJ, et al
    A plasma microRNA signature as a biomarker for acquired aplastic anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.151076.
    PubMed     Text format     Abstract available

  74. SARAF SL, Shah BN, Zhang X, Han J, et al
    APOL1, Alpha thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.154153.
    PubMed     Text format    

    August 2016
  75. GREIL J, Verga-Falzacappa MV, Echner NE, Behnisch W, et al
    Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation.
    Haematologica. 2016 Aug 4. pii: haematol.2016.147090.
    PubMed     Text format    

    April 2016
  76. DE FALCO L, Bruno M, Yilmaz-Keskin E, Sal E, et al
    The role of Matriptase-2 during the early postnatal development in humans.
    Haematologica. 2016;101:e126-8.
    PubMed     Text format    

    March 2016
  77. CHEN H, Choesang T, Li H, Sun S, et al
    Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation.
    Haematologica. 2016;101:297-308.
    PubMed     Text format     Abstract available

    February 2016
  78. NGUYEN KL, Tian X, Alam S, Mehari A, et al
    Elevated transpulmonary gradient and cardiac magnetic resonance-derived right ventricular remodeling predict poor outcomes in sickle cell disease.
    Haematologica. 2016;101:e40-3.
    PubMed     Text format    

  79. VALVERDE Y, Benson B, Gupta M, Gupta K, et al
    Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice.
    Haematologica. 2016;101:e44-7.
    PubMed     Text format    

    January 2016
  80. MORISHIMA S, Kashiwase K, Matsuo K, Azuma F, et al
    High risk HLA alleles for severe acute graft-versus-host disease and mortality in unrelated donor bone marrow transplantation.
    Haematologica. 2016 Jan 14. pii: haematol.2015.136903.
    PubMed     Text format     Abstract available

  81. SATO K, Feng X, Chen J, Li J, et al
    PPARgamma antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function.
    Haematologica. 2016;101:57-67.
    PubMed     Text format     Abstract available

  82. CASU C, Aghajan M, Oikonomidou PR, Guo S, et al
    Combination of Tmprss6- ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta-thalassemia intermedia.
    Haematologica. 2016;101:e8-e11.
    PubMed     Text format    

  83. DE SWART L, Hendriks JC, van der Vorm LN, Cabantchik ZI, et al
    Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders.
    Haematologica. 2016;101:38-45.
    PubMed     Text format     Abstract available

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