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Articles published in Haematologica

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Single Articles

    May 2019
  1. BERNAUDIN F, Dalle JH, Bories D, Peffault de Latour R, et al
    Long-term event-free survival, chimerism and fertility outcomes in 234 patients with sickle-cell anemia younger than 30 years after myeloablative conditioning and matched-sibling transplantation in France.
    Haematologica. 2019 May 16. pii: haematol.2018.213207.
    PubMed     Text format     Abstract available

    April 2019
  2. ROGERS ZR, Nakano TA, Olson TS, Bertuch AA, et al
    Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study.
    Haematologica. 2019 Apr 4. pii: haematol.2018.206540.
    PubMed     Text format     Abstract available

    March 2019
  3. CURSINO-SANTOS JR, Singh M, Senaldi E, Manwani D, et al
    Altered parasite life-cycle processes characterize Babesia divergens infection in human sickle cell anemia.
    Haematologica. 2019 Mar 28. pii: haematol.2018.214304.
    PubMed     Text format     Abstract available

  4. FATTIZZO B, Kulasekararaj AG, Hill A, Benson-Quarm N, et al
    Clinical and morphologic predictors of outcome in older aplastic anemia patients treated with eltrombopag.
    Haematologica. 2019 Mar 19. pii: haematol.2019.216374.
    PubMed     Text format    

  5. ELBADRY MI, Mizumaki H, Hosokawa K, Espinoza JL, et al
    Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia.
    Haematologica. 2019 Mar 19. pii: haematol.2018.210856.
    PubMed     Text format    

  6. ZAHR RS, Rampersaud E, Kang G, Weiss MJ, et al
    Children with sickle cell anemia and APOL1 genetic variants develop albuminuria early in life.
    Haematologica. 2019 Mar 19. pii: haematol.2018.212779.
    PubMed     Text format     Abstract available

  7. VARRICCHIO L, Planutis A, Manwani D, Jaffray J, et al
    Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient.
    Haematologica. 2019 Mar 14. pii: haematol.2018.209858.
    PubMed     Text format     Abstract available

  8. GIRELLI D, Busti F
    Anemia and adverse outcomes in the elderly: a detrimental inflammatory loop?
    Haematologica. 2019;104:417-419.
    PubMed     Text format    

    February 2019
  9. MORI M, Hira A, Yoshida K, Muramatsu H, et al
    Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients.
    Haematologica. 2019 Feb 21. pii: haematol.2018.207241.
    PubMed     Text format     Abstract available

    Antithymocyte globulin and cyclosporin: standard of care also for older patients with aplastic anemia.
    Haematologica. 2019;104:215-216.
    PubMed     Text format    

    January 2019
  11. MIANO M, Eikema DJ, Aljurf M, Van't Veer PJ, et al
    Stem cell transplantation for congenital dyserythropoietic anemia. An analysis from the European society for blood and marrow transplantation.
    Haematologica. 2019 Jan 24. pii: haematol.2018.206623.
    PubMed     Text format    

  12. STOFFEL NU, Lazrak M, Bellitir S, El Mir N, et al
    The opposing effects of acute inflammation and iron deficiency anemia on serum hepcidin and iron absorption in young women.
    Haematologica. 2019 Jan 10. pii: haematol.2018.208645.
    PubMed     Text format     Abstract available

    October 2018
  13. CAPPELLINI MD, Porter J, Origa R, Forni GL, et al
    Sotatercept, a novel transforming growth factor beta ligand trap, improves anemia in beta-thalassemia: a phase 2, open-label, dose-finding study.
    Haematologica. 2018 Oct 18. pii: haematol.2018.198887.
    PubMed     Text format     Abstract available

  14. WOUTERS HJCM, van der Klauw MM, de Witte T, Stauder R, et al
    Association of anemia with health-related quality of life and survival: a large population-based cohort study.
    Haematologica. 2018 Oct 11. pii: haematol.2018.195552.
    PubMed     Text format     Abstract available

  15. PARK S, Kosmider O, Maloisel F, Drenou B, et al
    Dyserythropoiesis evaluated by RED score and hepcidin/ferritin levels predicts response to erythropoietin in lower risk myelodysplastic syndromes.
    Haematologica. 2018 Oct 4. pii: haematol.2018.203158.
    PubMed     Text format     Abstract available

    September 2018
  16. ARTUSO I, Pettinato M, Nai A, Pagani A, et al
    Transient decrease of serum iron after acute erythropoietin treatment contributes to hepcidin inhibition by ERFE in mice.
    Haematologica. 2018 Sep 28. pii: haematol.2018.199810.
    PubMed     Text format    

  17. CONTEJEAN A, Resche-Rigon M, Tamburini J, Alcantara M, et al
    Aplastic anemia in the elderly: a nationwide survey on behalf of the French Reference Center for Aplastic Anemia.
    Haematologica. 2018 Sep 27. pii: haematol.2018.198440.
    PubMed     Text format     Abstract available

  18. JONGMANS MCJ, Diets IJ, Quarello P, Garelli E, et al
    Somatic reversion events point towards RPL4 as a novel disease gene in a condition resembling Diamond-Blackfan Anemia.
    Haematologica. 2018 Sep 13. pii: haematol.2018.200683.
    PubMed     Text format    

    July 2018
  19. RILEY LG, Heeney MM, Rudinger-Thirion J, Frugier M, et al
    The phenotypic spectrum of germline YARS2 variants: from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2.
    Haematologica. 2018 Jul 19. pii: haematol.2017.182659.
    PubMed     Text format     Abstract available

  20. BERHE S, Heeney MM, Campagna DR, Thompson JF, et al
    Recurrent heteroplasmy for the MT-ATP6 p.Ser148Asn (m.8969G>A) mutation in patients with syndromic congenital sideroblastic anemia of variable clinical severity.
    Haematologica. 2018 Jul 13. pii: haematol.2018.199109.
    PubMed     Text format    

  21. ADAIR JE, Chandrasekaran D, Sghia-Hughes G, Haworth KG, et al
    Novel lineage depletion preserves autologous blood stem cells for gene therapy of Fanconi anemia complementation group A.
    Haematologica. 2018 Jul 5. pii: haematol.2018.194571.
    PubMed     Text format     Abstract available

  22. SMITH F, Hopton S, Dallabona C, Gilberti M, et al
    Sideroblastic anemia with myopathy secondary to novel, pathogenic missense variants in the YARS2 gene.
    Haematologica. 2018 Jul 5. pii: haematol.2018.194464.
    PubMed     Text format    

    Complication free survival long-term after hemopoietic cell transplantation in thalassemia.
    Haematologica. 2018;103:1094-1096.
    PubMed     Text format    

    May 2018
  24. MCCABE A, Smith JNP, Costello A, Maloney J, et al
    Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression.
    Haematologica. 2018 May 17. pii: haematol.2018.189449.
    PubMed     Text format     Abstract available

    (Auto-)immune signature in aplastic anemia.
    Haematologica. 2018;103:747-749.
    PubMed     Text format    

  26. HSIEH MM, Tisdale JF
    Hematopoietic stem cell mobilization with plerixafor in sickle cell disease.
    Haematologica. 2018;103:749-750.
    PubMed     Text format    

    April 2018
  27. GIUDICE V, Banaszak LG, Gutierrez-Rodrigues F, Kajigaya S, et al
    Diagnostic and prognostic roles of circulating exosomal microRNAs in acquired aplastic anemia and myelodysplastic syndromes.
    Haematologica. 2018 Apr 19. pii: haematol.2017.182824.
    PubMed     Text format     Abstract available

  28. MADEDDU C, Gramignano G, Kotsonis P, Coghe F, et al
    Microenvironmental M1 tumor-associated macrophage polarization influences cancer-related anemia in advanced ovarian cancer: key role of Interleukin-6.
    Haematologica. 2018 Apr 19. pii: haematol.2018.191551.
    PubMed     Text format    

    March 2018
  29. WLODARSKI MW, Da Costa L, O'Donohue MF, Gastou M, et al
    Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia.
    Haematologica. 2018 Mar 29. pii: haematol.2017.177980.
    PubMed     Text format     Abstract available

  30. TEWARI S, Renney G, Brewin J, Gardner K, et al
    Proteomic analysis of plasma from children with sickle cell anemia and silent cerebral infarction.
    Haematologica. 2018 Mar 15. pii: haematol.2018.187815.
    PubMed     Text format     Abstract available

  31. GRIFFIN M, Kulasekararaj A, Gandhi S, Munir T, et al
    Concurrent treatment of aplastic anemia/Paroxysmal Nocturnal Hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience.
    Haematologica. 2018 Mar 15. pii: haematol.2017.183046.
    PubMed     Text format    

  32. VALLET N, de Fontbrune FS, Loschi M, Desmier D, et al
    Hematopoietic stem cell transplantation for patients with paroxysmal nocturnal hemoglobinuria previously treated with eculizumab: a retrospective study of 21 patients from SFGM-TC centers.
    Haematologica. 2018;103:e103-e105.
    PubMed     Text format    

  33. ANDOLFO I, Manna F, De Rosa G, Rosato BE, et al
    PIEZO1-R1864H rare variant accounts for a genetic phenotype-modifier role in dehydrated hereditary stomatocytosis.
    Haematologica. 2018;103:e94-e97.
    PubMed     Text format    

    February 2018
  34. GIUDICE V, Feng X, Lin Z, Hu W, et al
    Deep sequencing and flow cytometric characterization of expanded effector memory CD8+CD57+ T cells frequently reveals T-cell receptor Vbeta oligoclonality and CDR3 homology in acquired aplastic anemia.
    Haematologica. 2018 Feb 1. pii: haematol.2017.176701.
    PubMed     Text format     Abstract available

  35. HATTA S, Fujiwara T, Yamamoto T, Saito K, et al
    A defined culture method enabling the establishment of ring sideroblasts from induced pluripotent cells of X-linked sideroblastic anemia.
    Haematologica. 2018 Feb 1. pii: haematol.2017.179770.
    PubMed     Text format    

  36. HANUDEL MR, Rappaport M, Chua K, Gabayan V, et al
    Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease.
    Haematologica. 2018 Feb 1. pii: haematol.2017.181743.
    PubMed     Text format    

  37. VAN STRAATEN S, Bierings M, Bianchi P, Akiyoshi K, et al
    Worldwide study of hematopoietic allogeneic stem cell transplantation in pyruvate kinase deficiency.
    Haematologica. 2018;103:e82-e86.
    PubMed     Text format    

  38. BALASUBRAMANIAN SK, Sadaps M, Thota S, Aly M, et al
    Rational management approach to pure red cell aplasia.
    Haematologica. 2018;103:221-230.
    PubMed     Text format     Abstract available

  39. CASU C, Presti VL, Oikonomidou PR, Melchiori L, et al
    Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of beta-thalassemia intermedia and major.
    Haematologica. 2018;103:e46-e49.
    PubMed     Text format    

    December 2017
  40. BOTTEGA R, Nicchia E, Cappelli E, Ravera S, et al
    Hypomorphic FANCA mutations correlate with mild mitochondrial and clinical phenotype in Fanconi anemia.
    Haematologica. 2017 Dec 21. pii: haematol.2017.176131.
    PubMed     Text format     Abstract available

  41. PASQUIER F, Marty C, Balligand T, Verdier F, et al
    New pathogenic mechanisms induced by germline erythropoietin receptor mutations in primary erythrocytosis.
    Haematologica. 2017 Dec 21. pii: haematol.2017.176370.
    PubMed     Text format     Abstract available

  42. FANG X, Shen F, Lechauve C, Xu P, et al
    miR-144/451 represses the LKB1/AMPK/mTOR pathway to promote red cell precursor survival during recovery from acute anemia.
    Haematologica. 2017 Dec 21. pii: haematol.2017.177394.
    PubMed     Text format     Abstract available

    November 2017
  43. ANAMPA J, Haque T, Murakhovskaya I, Wang Y, et al
    Macrocytosis and dysplastic anemia is associated with the Cyclin-Dependent Kinase 4/6 inhibitor palbociclib in metastatic breast cancer.
    Haematologica. 2017 Nov 30. pii: haematol.2017.181941.
    PubMed     Text format    

  44. LENGLINE E, Drenou B, Peterlin P, Tournilhac O, et al
    Nationwide survey on the use of eltrombopag in patients with severe aplastic anemia: a report on behalf of the French reference center for aplastic anemia.
    Haematologica. 2017 Nov 23. pii: haematol.2017.176339.
    PubMed     Text format     Abstract available

  45. PENKERT RR, Hurwitz JL, Thomas P, Rosch J, et al
    Inflammatory molecule reduction with hydroxyurea therapy in children with sickle cell anemia.
    Haematologica. 2017 Nov 16. pii: haematol.2017.177360.
    PubMed     Text format    

    October 2017
  46. BALAIAN E, Wobus M, Weidner H, Baschant U, et al
    Erythropoietin inhibits osteoblast function in myelodysplastic syndromes via the canonical Wnt pathway.
    Haematologica. 2017 Oct 27. pii: haematol.2017.172726.
    PubMed     Text format     Abstract available

  47. CHADEBECH P, Loustau V, Janvier D, Languille L, et al
    Clinical severity in adult warm autoimmune hemolytic anemia and its relationship to antibody specificity.
    Haematologica. 2017 Oct 12. pii: haematol.2017.175976.
    PubMed     Text format     Abstract available

  48. CLUZEAU T, McGraw KL, Irvine B, Masala E, et al
    Pro-inflammatory proteins S100A9 and TNFalpha suppress erythropoietin elaboration in myelodysplastic syndromes.
    Haematologica. 2017 Oct 5. pii: haematol.2016.158857.
    PubMed     Text format     Abstract available

    September 2017
  49. VENUGOPAL P, Moore S, Lawrence DM, George AJ, et al
    Self-reverting mutations partially correct the blood phenotype in a Diamond Blackfan Anemia patient.
    Haematologica. 2017 Sep 29. pii: haematol.2017.166678.
    PubMed     Text format    

    August 2017
  50. CLINKENBEARD EL, Hanudel MR, Stayrook KR, Appaiah HN, et al
    Erythropoietin stimulates murine and human Fibroblast growth factor-23, revealing novel roles for bone and bone marrow.
    Haematologica. 2017 Aug 17. pii: haematol.2017.167882.
    PubMed     Text format    

    July 2017
  51. VAHT K, Goransson M, Carlson K, Isaksson C, et al
    Incidence and outcome of acquired aplastic anemia-real-world data from patients diagnosed in Sweden from 2000-2011.
    Haematologica. 2017 Jul 27. pii: haematol.2017.169862.
    PubMed     Text format     Abstract available

  52. VAN DER HEM JG, de Wreede LC, Brand A, Veelken H, et al
    Long-term risk of cancer development in adult patients with idiopathic aplastic anemia after treatment with anti-thymocyte globulin.
    Haematologica. 2017 Jul 13. pii: haematol.2017.171215.
    PubMed     Text format    

    Antithymocyte globulin and transplants for aplastic anemia.
    Haematologica. 2017;102:1137-1138.
    PubMed     Text format    

    June 2017
  54. OTTO JM, Plumb JOM, Clissold E, Kumar S, et al
    Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia.
    Haematologica. 2017 Jun 8. pii: haematol.2017.169680.
    PubMed     Text format     Abstract available

  55. RAFII H, Bernaudin F, Rouard H, Vanneaux V, et al
    Family cord blood banking for sickle cell disease: a twenty-year experience in two dedicated public cord blood banks.
    Haematologica. 2017;102:976-983.
    PubMed     Text format     Abstract available

  56. URAS IZ, Scheicher RM, Kollmann K, Glosmann M, et al
    Cdk6 contributes to cytoskeletal stability in erythroid cells.
    Haematologica. 2017;102:995-1005.
    PubMed     Text format     Abstract available

    May 2017
  57. RUSSO R, Andolfo I, Gambale A, De Rosa G, et al
    GATA1 erythroid-specific regulation of SEC23B expression and its implication in the pathogenesis of Congenital Dyserythropoietic Anemia type II.
    Haematologica. 2017 May 26. pii: haematol.2016.162966.
    PubMed     Text format    

    April 2017
  58. MAITRA P, Caughey M, Robinson L, Desai PC, et al
    Risk factors for mortality in adult patients with sickle cell disease: a meta-analysis of studies in North America and Europe.
    Haematologica. 2017;102:626-636.
    PubMed     Text format     Abstract available

  59. PIEL FB, Tewari S, Brousse V, Analitis A, et al
    Associations between environmental factors and hospital admissions for sickle cell disease.
    Haematologica. 2017;102:666-675.
    PubMed     Text format     Abstract available

    March 2017
  60. ZHOU Y, He Y, Xing W, Zhang P, et al
    Abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.
    Haematologica. 2017 Mar 24. pii: haematol.2016.158717.
    PubMed     Text format     Abstract available

  61. KEKRE N, Zhang Y, Zhang MJ, Carreras J, et al
    Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia.
    Haematologica. 2017 Mar 24. pii: haematol.2017.164459.
    PubMed     Text format     Abstract available

  62. KOBAYASHI M, Kato H, Hada H, Itoh-Nakadai A, et al
    Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.
    Haematologica. 2017;102:454-465.
    PubMed     Text format     Abstract available

  63. YUAN X, Gavriilaki E, Thanassi JA, Yang G, et al
    Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.
    Haematologica. 2017;102:466-475.
    PubMed     Text format     Abstract available

    February 2017
  64. MILLOT S, Delaby C, Moulouel B, Lefebvre T, et al
    Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Gunther disease model.
    Haematologica. 2017;102:260-270.
    PubMed     Text format     Abstract available

  65. SRIVASTAVA A, Shaji RV
    Cure for thalassemia major - from allogeneic hematopoietic stem cell transplantation to gene therapy.
    Haematologica. 2017;102:214-223.
    PubMed     Text format     Abstract available

  66. KIM K, Li J, Barazia A, Tseng A, et al
    ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease.
    Haematologica. 2017;102:246-259.
    PubMed     Text format     Abstract available

  67. XIN J, Breslin P, Wei W, Li J, et al
    Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice.
    Haematologica. 2017;102:295-307.
    PubMed     Text format     Abstract available

    January 2017
  68. WEIR NA, Saiyed R, Alam S, Conrey A, et al
    Prostacyclin-analog therapy in sickle cell pulmonary hypertension.
    Haematologica. 2017 Jan 25. pii: haematol.2015.131227.
    PubMed     Text format     Abstract available

  69. BELL JB, Abedin S, Platanias LC
    Circulating microRNAs: promising biomarkers in aplastic anemia.
    Haematologica. 2017;102:1-2.
    PubMed     Text format    

    December 2016
  70. CRAZZOLARA R, Kropshofer G, Haas OA, Matthes-Martin S, et al
    Reduced-intensity conditioning and stem cell transplantation in infants with Diamond Blackfan anemia.
    Haematologica. 2016 Dec 7. pii: haematol.2016.157149.
    PubMed     Text format    

  71. IKEDA F, Yoshida K, Toki T, Uechi T, et al
    Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia.
    Haematologica. 2016 Dec 1. pii: haematol.2016.153932.
    PubMed     Text format    

    November 2016
  72. HANUDEL MR, Rappaport M, Gabayan V, Jung G, et al
    Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model.
    Haematologica. 2016 Nov 24. pii: haematol.2016.150433.
    PubMed     Text format    

    September 2016
  73. LATOUR C, Wlodarczyk MF, Jung G, Gineste A, et al
    Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.150227.
    PubMed     Text format     Abstract available

  74. HOSOKAWA K, Kajigaya S, Feng X, Desierto MJ, et al
    A plasma microRNA signature as a biomarker for acquired aplastic anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.151076.
    PubMed     Text format     Abstract available

  75. SARAF SL, Shah BN, Zhang X, Han J, et al
    APOL1, Alpha thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.154153.
    PubMed     Text format    

    August 2016
  76. GREIL J, Verga-Falzacappa MV, Echner NE, Behnisch W, et al
    Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation.
    Haematologica. 2016 Aug 4. pii: haematol.2016.147090.
    PubMed     Text format    

    April 2016
  77. DE FALCO L, Bruno M, Yilmaz-Keskin E, Sal E, et al
    The role of Matriptase-2 during the early postnatal development in humans.
    Haematologica. 2016;101:e126-8.
    PubMed     Text format    

    March 2016
  78. CHEN H, Choesang T, Li H, Sun S, et al
    Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation.
    Haematologica. 2016;101:297-308.
    PubMed     Text format     Abstract available

    February 2016
  79. NGUYEN KL, Tian X, Alam S, Mehari A, et al
    Elevated transpulmonary gradient and cardiac magnetic resonance-derived right ventricular remodeling predict poor outcomes in sickle cell disease.
    Haematologica. 2016;101:e40-3.
    PubMed     Text format    

  80. VALVERDE Y, Benson B, Gupta M, Gupta K, et al
    Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice.
    Haematologica. 2016;101:e44-7.
    PubMed     Text format    

    January 2016
  81. MORISHIMA S, Kashiwase K, Matsuo K, Azuma F, et al
    High risk HLA alleles for severe acute graft-versus-host disease and mortality in unrelated donor bone marrow transplantation.
    Haematologica. 2016 Jan 14. pii: haematol.2015.136903.
    PubMed     Text format     Abstract available

  82. SATO K, Feng X, Chen J, Li J, et al
    PPARgamma antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function.
    Haematologica. 2016;101:57-67.
    PubMed     Text format     Abstract available

  83. CASU C, Aghajan M, Oikonomidou PR, Guo S, et al
    Combination of Tmprss6- ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta-thalassemia intermedia.
    Haematologica. 2016;101:e8-e11.
    PubMed     Text format    

  84. DE SWART L, Hendriks JC, van der Vorm LN, Cabantchik ZI, et al
    Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders.
    Haematologica. 2016;101:38-45.
    PubMed     Text format     Abstract available

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