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Articles published in Haematologica

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Single Articles


    November 2022
  1. LIU YL, Shibuya A, Glader B, Wilkes MC, et al
    Animal models of Diamond-Blackfan anemia: updates and challenges.
    Haematologica. 2022 Nov 17. doi: 10.3324/haematol.2022.282042.
    PubMed     Abstract available


  2. AFZALI-HASHEMI L, Vaclavu L, Wood JC, Biemond BJ, et al
    Assessment of functional shunting in patients with sickle cell disease.
    Haematologica. 2022;107:2708-2719.
    PubMed     Abstract available


  3. LI X, Chatla S, Wilson AF, Wu L, et al
    Persistent DNA damage and oncogenic stress-induced Trem1 promotes leukemia in mice.
    Haematologica. 2022;107:2576-2588.
    PubMed     Abstract available


  4. ROSSATO P, Federti E, Matte A, Glantschnig H, et al
    Evidence of protective effects of recombinant ADAMTS13 in a humanized model of sickle cell disease.
    Haematologica. 2022;107:2650-2660.
    PubMed     Abstract available


    October 2022
  5. HERNANDEZ G, Romero-Cortadellas L, Ferrer-Cortes X, Venturi V, et al
    Mutations in the RACGAP1 gene cause autosomal recessive congenital dyserythropoietic anemia type III.
    Haematologica. 2022 Oct 6. doi: 10.3324/haematol.2022.281277.
    PubMed     Abstract available


  6. GANGAT N, Bleeker J, Lynch D, Olteanu H, et al
    Daratumumab for treatment-refractory acquired idiopathic pure red cell aplasia.
    Haematologica. 2022;107:2523-2526.
    PubMed    


  7. GALADANCI NA, Johnson W, Carson A, Hellemann G, et al
    Factors associated with left ventricular hypertrophy in children with sickle cell disease: results from the DISPLACE study.
    Haematologica. 2022;107:2466-2473.
    PubMed     Abstract available


    September 2022
  8. BALDUINI CL
    Images from the Haematologica Atlas of Hematologic Cytology: schistocytes in thrombotic microangiopathies.
    Haematologica. 2022;107:2008.
    PubMed    


  9. KHWAJA J, D'Sa S, Minnema MC, Kersten MJ, et al
    IgM monoclonal gammopathies of clinical significance: diagnosis and management.
    Haematologica. 2022;107:2037-2050.
    PubMed     Abstract available


  10. GILAD O, Dgany O, Noy-Lotan S, Krasnov T, et al
    Syndromes predisposing to leukemia are a major cause of inherited cytopenias in children.
    Haematologica. 2022;107:2081-2095.
    PubMed     Abstract available


    August 2022
  11. INVERNIZZI R
    Images from the Haematologica Atlas of Hematologic Cytology: congenital dyserythropoietic anemia type II.
    Haematologica. 2022;107:1736.
    PubMed    


  12. BENCHEIKH L, Nguyen KA, Chadebech P, Kiger L, et al
    Preclinical evaluation of the preservation of red blood cell concentrates by hypoxic storage technology for transfusion in sickle cell disease.
    Haematologica. 2022;107:1944-1949.
    PubMed    


  13. LEMAIRE B, Abramowski SW
    Alloimmunization against Fy3 is a serious threat in the era of cell therapy.
    Haematologica. 2022;107:1986-1987.
    PubMed    


  14. KNAUS A, Vergez F, Garcia C, Engels H, et al
    Occurrence of a paroxysmal nocturnal hemoglobinuria clone in an essential thrombocythemia: a link between PIGV and MPL.
    Haematologica. 2022;107:1989-1993.
    PubMed    


  15. LOPINTO J, Gendreau S, Berti E, Bartolucci P, et al
    Effects of corticosteroids in patients with sickle cell disease and acute complications: a systematic review and meta-analysis.
    Haematologica. 2022;107:1914-1921.
    PubMed     Abstract available


  16. GUTIERREZ-RODRIGUES F, Beerman I, Groarke EM, Patel BA, et al
    Utility of plasma cell-free DNA for de novo detection and quantification of clonal hematopoiesis.
    Haematologica. 2022;107:1815-1826.
    PubMed     Abstract available


    July 2022
  17. DE SOUZA LV, Hoffmann A, Fischer C, Petzer V, et al
    Comparative analysis of oral and intravenous iron therapy in rat models of inflammatory anemia and iron deficiency.
    Haematologica. 2022 Jul 7. doi: 10.3324/haematol.2022.281149.
    PubMed     Abstract available


  18. INVERNIZZI R
    Images from the Haematologica Atlas of Hematologic Cytology: parvovirus-induced pure red cell aplasia.
    Haematologica. 2022;107:1493.
    PubMed    


  19. DERCHI G, Musallam KM, Pinto VM, Graziadei G, et al
    Tricuspid-valve regurgitant jet velocity as a risk factor for death in beta-thalassemia.
    Haematologica. 2022;107:1714-1718.
    PubMed    


  20. ROTH A, Barcellini W, D'Sa S, Miyakawa Y, et al
    Complement C1s inhibition with sutimlimab results in durable response in cold agglutinin disease: CARDINAL study 1-year interim follow-up results.
    Haematologica. 2022;107:1698-1702.
    PubMed    


  21. ALLARD P, Alhaj N, Lobitz S, Cario H, et al
    Genetic modifiers of fetal hemoglobin affect the course of sickle cell disease in patients treated with hydroxyurea.
    Haematologica. 2022;107:1577-1588.
    PubMed     Abstract available


  22. VERSTOVSEK S, Mesa R, Talpaz M, Kiladjian JJ, et al
    Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia.
    Haematologica. 2022;107:1599-1607.
    PubMed     Abstract available


  23. ABUGA KM, Muriuki JM, Uyoga SM, Mwai K, et al
    Hepcidin regulation in Kenyan children with severe malaria and non-typhoidal Salmonella bacteremia.
    Haematologica. 2022;107:1589-1598.
    PubMed     Abstract available


    June 2022
  24. DONG P, Chen L, Wu H, Huo J, et al
    Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia.
    Haematologica. 2022 Jun 23. doi: 10.3324/haematol.2021.280292.
    PubMed     Abstract available


  25. RODEGHIERO F
    Introduction to a review series on the treatment of thrombocytopenic disorders: something old, something new.
    Haematologica. 2022;107:1239-1242.
    PubMed    


  26. NISHIMURA JI, Ando K, Masuko M, Noji H, et al
    Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria.
    Haematologica. 2022;107:1483-1488.
    PubMed    


  27. KULOZIK AE
    Does the world need germline editing for beta-thalassemia?
    Haematologica. 2022;107:1235-1236.
    PubMed    


  28. GEISNESS AC, Azul M, Williams D, Szafraniec H, et al
    Ionophore-mediated swelling of erythrocytes as a therapeutic mechanism in sickle cell disease.
    Haematologica. 2022;107:1438-1447.
    PubMed     Abstract available


    May 2022
  29. XU ZL, Xu LP, Wu DP, Wang SQ, et al
    Comparable long-term outcomes between upfront haploidentical and identical sibling donor transplant in aplastic anemia: a national registry-based study.
    Haematologica. 2022 May 26. doi: 10.3324/haematol.2022.280758.
    PubMed     Abstract available


    April 2022
  30. ROSATO BE, Alper SL, Tomaiuolo G, Russo R, et al
    Hereditary anemia caused by multilocus inheritance of PIEZO1, SLC4A1 and ABCB6 mutations: a diagnostic and therapeutic challenge.
    Haematologica. 2022 Apr 21. doi: 10.3324/haematol.2022.280799.
    PubMed     Abstract available


  31. ALTINTAS B, Giri N, McReynolds LJ, Best A, et al
    Genotype-phenotype and outcome associations in patients with Fanconi anemia: The National Cancer Institute cohort.
    Haematologica. 2022 Apr 14. doi: 10.3324/haematol.2021.279981.
    PubMed     Abstract available


  32. BREGOLAT NF, Ruetten M, Da Silva MC, Aboouf MA, et al
    Iron- and erythropoietin-resistant anemia in a spontaneous breast cancer mouse model.
    Haematologica. 2022 Apr 7. doi: 10.3324/haematol.2022.280732.
    PubMed     Abstract available


  33. BENNINGHOVEN-FREY KM, Neuhaus N, Lahtinen AK, Krallmann C, et al
    Early testicular maturation is sensitive to depletion of spermatogonial pool in sickle cell disease.
    Haematologica. 2022;107:975-979.
    PubMed    


    February 2022
  34. AVENOSO D, Marsh JCW, Potter V, Pagliuca A, et al
    SARS-CoV-2 infection in aplastic anemia.
    Haematologica. 2022;107:541-543.
    PubMed    


  35. ABDULMALIK O, Darwish NHE, Muralidharan-Chari V, Taleb MA, et al
    Sulfated non-anticoagulant heparin derivative modifies intracellular hemoglobin, inhibits cell sickling in vitro, and prolongs survival of sickle cell mice under hypoxia.
    Haematologica. 2022;107:532-540.
    PubMed     Abstract available


  36. PINCEZ T, Fernandes H, Leblanc T, Michel G, et al
    Long term follow-up of pediatric-onset Evans syndrome: broad immunopathological manifestations and high treatment burden.
    Haematologica. 2022;107:457-466.
    PubMed     Abstract available


  37. CASALE M, Forni GL, Cassinerio E, Pasquali D, et al
    Risk factors for endocrine complications in transfusion-dependent thalassemia patients on chelation therapy with deferasirox: a risk assessment study from a multi-center nation-wide cohort.
    Haematologica. 2022;107:467-477.
    PubMed     Abstract available


    January 2022
  38. BREWIN J, El Hoss S, Strouboulis J, Rees D, et al
    A novel index to evaluate ineffective erythropoiesis in hematological diseases offers insights into sickle cell disease.
    Haematologica. 2022;107:338-341.
    PubMed    


  39. TZOUNAKAS VL, Anastasiadi AT, Stefanoni D, Cendali F, et al
    Beta thalassemia minor is a beneficial determinant of red blood cell storage lesion.
    Haematologica. 2022;107:112-125.
    PubMed     Abstract available


    December 2021
  40. ELABBADI A, Voiriot G, Tristan A, Gibelin A, et al
    Lower respiratory tract infection with Staphylococcus aureus in sickle-cell adult patients with severe acute chest syndrome - the STAPHACS Study.
    Haematologica. 2021;106:3236-3239.
    PubMed    


    November 2021
  41. HOOGENBOOM WS, Fleysher R, Soby S, Mirhaji P, et al
    Individuals with sickle cell disease and sickle cell trait demonstrate no increase in mortality or critical illness from COVID-19 - a fifteen hospital observational study in the Bronx, New York.
    Haematologica. 2021;106:3014-3016.
    PubMed    


    October 2021
  42. BROUSSE V, Holvoet L, Pescarmona R, Viel S, et al
    Low incidence of COVID-19 severe complications in a large cohort of children with sickle cell disease: a protective role for basal interferon-1 activation?
    Haematologica. 2021;106:2746-2748.
    PubMed    


  43. VANDORPE DH, Shmukler BE, Ilboudo Y, Bhasin S, et al
    A Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic etiologies.
    Haematologica. 2021;106:2759-2762.
    PubMed    


  44. EL HOSS S, Cochet S, Godard A, Yan H, et al
    Fetal hemoglobin rescues ineffective erythropoiesis in sickle cell disease.
    Haematologica. 2021;106:2707-2719.
    PubMed     Abstract available


    September 2021
  45. MUSALLAM KM, Vitrano A, Meloni A, Pollina SA, et al
    Survival and causes of death in 2,033 patients with non-transfusion-dependent beta-thalassemia
    Haematologica. 2021;106:2489-2492.
    PubMed    


  46. MIWATA S, Narita A, Okuno Y, Suzuki K, et al
    Clinical diagnostic value of telomere length measurement in inherited bone marrow failure syndromes.
    Haematologica. 2021;106:2511-2515.
    PubMed    


  47. LIZARRALDE-IRAGORRI MA, Lefevre SD, Cochet S, El Hoss S, et al
    Oxidative stress activates red cell adhesion to laminin in sickle cell disease.
    Haematologica. 2021;106:2478-2488.
    PubMed     Abstract available


  48. VENUGOPAL J, Wang J, Mawri J, Guo C, et al
    Interleukin-1 receptor inhibition reduces stroke size in a murine model of sickle cell disease.
    Haematologica. 2021;106:2469-2477.
    PubMed     Abstract available


  49. KOUNTOURIS P, Michailidou K, Christou S, Hadjigavriel M, et al
    Effect of HBB genotype on survival in a cohort of transfusion-dependent thalassemia patients in Cyprus.
    Haematologica. 2021;106:2458-2468.
    PubMed     Abstract available


    August 2021
  50. COLIN E, Courtois G, Brouzes C, Pulman J, et al
    Biallelic mutations in the SARS2 gene presenting as congenital sideroblastic anemia.
    Haematologica. 2021 Aug 19. doi: 10.3324/haematol.2021.279138.
    PubMed     Abstract available


  51. BOATENG LA, Schonewille H, Ligthart PC, Javadi A, et al
    One third of alloantibodies in patients with sickle cell disease transfused with African blood are missed by the standard red blood cell test panel.
    Haematologica. 2021;106:2274-2276.
    PubMed    


    July 2021
  52. WANG C, McGraw KL, McLemore AF, Komrokji R, et al
    Dual pyroptotic biomarkers predict erythroid response in lower risk non-del(5q) myelodysplastic syndromes treated with lenalidomide and recombinant erythropoietin.
    Haematologica. 2021 Jul 29. doi: 10.3324/haematol.2021.278855.
    PubMed     Abstract available


  53. BEHRENS YL, Gohring G, Bawadi R, Coktu S, et al
    A novel classification of hematologic conditions in patients with Fanconi anemia.
    Haematologica. 2021 Jul 1. doi: 10.3324/haematol.2021.279332.
    PubMed     Abstract available


  54. LINDER GE, Chou ST
    Red cell transfusion and alloimmunization in sickle cell disease.
    Haematologica. 2021;106:1805-1815.
    PubMed     Abstract available


  55. KAUR K, Huang Y, Raman SV, Kraut E, et al
    Myocardial injury and coronary microvascular disease in sickle cell disease.
    Haematologica. 2021;106:2018-2021.
    PubMed    


  56. GILMARTIN AG, Groy A, Gore ER, Atkins C, et al
    In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor.
    Haematologica. 2021;106:1979-1987.
    PubMed     Abstract available


    June 2021
  57. BREWIN JN, Rooks H, Gardner K, Senior H, et al
    Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC).
    Haematologica. 2021;106:1770-1773.
    PubMed     Abstract available


  58. LAVINYA AA, Razali RA, Razak MA, Mohamed R, et al
    Homozygous Southeast Asian Ovalocytosis in five live-born neonates.
    Haematologica. 2021;106:1758-1761.
    PubMed     Abstract available


  59. MIKKELSEN SU, Safavi S, Dimopoulos K, O'Rourke CJ, et al
    Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance.
    Haematologica. 2021;106:1762-1766.
    PubMed     Abstract available


  60. SRISUWANANUKORN A, Han J, Raslan R, Gowhari M, et al
    Antimicrobial resistance is a risk factor for mortality in adults with sickle cell disease.
    Haematologica. 2021;106:1745-1748.
    PubMed     Abstract available


  61. SINGER ST, Fischer R, Allen I, Lal A, et al
    Pituitary iron and factors predictive of fertility status in transfusion dependent thalassemia.
    Haematologica. 2021;106:1740-1744.
    PubMed     Abstract available


  62. ALLALI S, Taylor M, Brice J, Montalembert M, et al
    Chronic organ injuries in children with sickle cell disease.
    Haematologica. 2021;106:1535-1544.
    PubMed     Abstract available


    May 2021
  63. PELLEGRIN S, Severn CE, Toye AM
    Towards manufactured red blood cells for the treatment of inherited anemia.
    Haematologica. 2021 May 27. doi: 10.3324/haematol.2020.268847.
    PubMed     Abstract available


  64. MESSONNIER LA, Riccetti M, Chatel B, Galacteros F, et al
    How to implement endurance exercise training in sickle cell disease.
    Haematologica. 2021;106:1476-1479.
    PubMed    


    April 2021
  65. ZAIMOKU Y, Patel BA, Shalhoub R, Groarke EM, et al
    Predicting response of severe aplastic anemia to immunosuppression combined with eltrombopag.
    Haematologica. 2021 Apr 29. doi: 10.3324/haematol.2021.278413.
    PubMed     Abstract available


  66. BROUSSE V, Pondarre C, Kossorotoff M, Arnaud C, et al
    Brain injury pathophysiology study by a multimodal approach in children with sickle cell anemia with no intra or extra cranial arteriopathy.
    Haematologica. 2021 Apr 22. doi: 10.3324/haematol.2020.278226.
    PubMed     Abstract available


  67. CORRE T, Ponte B, Pivin E, Pruijm M, et al
    Heritability and association with distinct genetic loci of erythropoietin levels in the general population.
    Haematologica. 2021 Apr 8. doi: 10.3324/haematol.2021.278389.
    PubMed     Abstract available


  68. CORRE T, Ponte B, Pivin E, Pruijm M, et al
    Heritability and association with distinct genetic loci of erythropoietin levels in the general population.
    Haematologica. 2021 Apr 8. doi: 10.3324/haematol.2021.278389.
    PubMed     Abstract available


  69. NANOU A, Toumpeki C, Fanis P, Bianchi N, et al
    Sex-specific transcriptional profiles identified in beta-thalassemia patients.
    Haematologica. 2021;106:1207-1211.
    PubMed    


    March 2021
  70. AL-SAMKARI H, Kessler CM, Auerbach M
    Recognition of thrombotic risk of thrombocytosis in iron deficiency
    Haematologica. 2021;106:661-663.
    PubMed    


  71. BAROZZI S, Di Buduo CA, Marconi C, Bozzi V, et al
    Pathogenetic and clinical study of a patient with thrombocytopenia due to the p.E527K gain-of-function variant of SRC.
    Haematologica. 2021;106:918-922.
    PubMed    


  72. BOUSSAID I, Le Goff S, Floquet C, Gautier EF, et al
    Integrated analyses of translatome and proteome identify the rules of translation selectivity in RPS14-deficient cells.
    Haematologica. 2021;106:746-758.
    PubMed     Abstract available


  73. JIMENEZ K, Leitner F, Leitner A, Scharbert G, et al
    Iron deficiency-induced thrombocytosis increases thrombotic tendency in rats.
    Haematologica. 2021;106:782-794.
    PubMed     Abstract available


    February 2021
  74. KORPORAAL A, Gillemans N, Heshusius S, Cantu I, et al
    Hemoglobin switching in mice carrying the Klf1(Nan) variant.
    Haematologica. 2021;106:464-473.
    PubMed     Abstract available


    January 2021
  75. LIU Y, Dahl M, Debnath S, Rothe M, et al
    Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector.
    Haematologica. 2021 Jan 14. doi: 10.3324/haematol.2020.269142.
    PubMed     Abstract available


  76. STONE EF, Avecilla ST, Wuest DL, Lomas-Francis C, et al
    Severe delayed hemolytic transfusion reaction due to anti-Fy3 in a patient with sickle cell disease undergoing red cell exchange prior to hematopoietic progenitor cell collection for gene therapy.
    Haematologica. 2021;106:310-312.
    PubMed    


  77. BLOMBERY P, Fox L, Ryland GL, Thompson ER, et al
    Utility of clinical comprehensive genomic characterization for diagnostic categorization in patients presenting with hypocellular bone marrow failure syndromes.
    Haematologica. 2021;106:64-73.
    PubMed     Abstract available


  78. BRODSKY RA, Peffault de Latour R, Rottinghaus ST, Roth A, et al
    Characterization of breakthrough hemolysis events observed in the phase 3 randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria.
    Haematologica. 2021;106:230-237.
    PubMed     Abstract available


    December 2020
  79. BARCIA G, Pandithan D, Ruzzenente B, Assouline Z, et al
    Biallelic IARS2 mutations presenting as sideroblastic anemia.
    Haematologica. 2020;Online ahead of print:0.
    PubMed     Abstract available


  80. KIETZMANN T
    Hypoxia-inducible erythropoietin expression: details matter.
    Haematologica. 2020;105:2704-2706.
    PubMed    


    November 2020
  81. ATAGA KI, Zhou Q, Derebail VK, Saraf SL, et al
    Rapid decline in estimated glomerular filtration rate in sickle cell anemia: results of a multicenter pooled analysis.
    Haematologica. 2020;Online ahead of print.
    PubMed     Abstract available


  82. BALDUINI CL
    100-year-old Haematologica images: bothriocephalus and pernicious anemia.
    Haematologica. 2020;105:2497.
    PubMed    


  83. MENAPACE LA, Thein SL
    COVID-19 and sickle cell disease.
    Haematologica. 2020;105:2501-2504.
    PubMed    


    October 2020
  84. TELEN MJ
    Pyridoxamine: another vitamin for sickle cell disease?
    Haematologica. 2020;105:2348-2350.
    PubMed    


    September 2020
  85. PATEL BA, Ghannam J, Groarke EM, Goswami M, et al
    Detectable mutations precede late myeloid neoplasia in aplastic anemia.
    Haematologica. 2020;Online ahead of print.
    PubMed    


  86. TELFER P, De la Fuente J, Sohal M, Brown R, et al
    Real-time national survey of COVID-19 in hemoglobinopathy and rare inherited anemia patients.
    Haematologica. 2020;Online ahead of print.
    PubMed    


  87. MODEPALLI S, Hattangadi SM
    Novel use for selective inhibitors of nuclear export in beta-thalassemia: block of HSP70 export from the nucleus via exportin Xpo1 improves ineffective erythropoiesis.
    Haematologica. 2020;105:2188-2189.
    PubMed    


    July 2020
  88. IMMACOLATA ANDOLFO, Stefania Martone, Michela Ribersani, Simona Bianchi, et al
    Apparent recessive inheritance of sideroblastic anemia type 2 due to uniparental isodisomy at the SLC25A38 locus.
    Haematologica. 2020;105:2883-2886.
    PubMed    


  89. GIRELLI D, Busti F
    Replacing the suppressed hormone: toward a better treatment for iron overload in beta-thalassemia major?
    Haematologica. 2020;105:1752-1754.
    PubMed    


    June 2020
  90. SUBARNA CHAKRAVORTY, Giselle Padmore-Payne, Fester Ike, Virginia Tshibangu, et al
    COVID-19 in patients with sickle cell disease - a case series from a UK Tertiary Hospital.
    Haematologica. 2020;105:2691-2693.
    PubMed    


    March 2020
  91. NARLA A, Mohandas N
    Staying hydrated is important also for erythroblasts.
    Haematologica. 2020;105:528-529.
    PubMed    


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