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Articles published in Cardiovasc Res

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    October 2023
  1. NIELSEN MB, Colak Y, Benn M, Mason A, et al
    Plasma adiponectin levels and risk of heart failure, atrial fibrillation, aortic valve stenosis, and myocardial infarction: large scale observational and Mendelian randomization evidence.
    Cardiovasc Res. 2023 Oct 28:cvad162. doi: 10.1093.
    PubMed     Abstract available

  2. JONES CA, Wallace MJ, Bandaru P, Woodbury ED, et al
    E-cigarettes and arrhythmogenesis: a comprehensive review of pre-clinical studies and their clinical implications.
    Cardiovasc Res. 2023;119:2157-2164.
    PubMed     Abstract available

    September 2023
  3. VENKATESHAPPA R, Hunter DV, Muralidharan P, Nagalingam RS, et al
    Targeted activation of hERG channels rescues electrical instability induced by the hERG R56Q+/- Long QT Syndrome variant.
    Cardiovasc Res. 2023 Sep 21:cvad155. doi: 10.1093.
    PubMed     Abstract available

  4. LAKIN R, Polidovitch N, Yang S, Parikh M, et al
    Cardiomyocyte and endothelial cells play distinct roles in the tumor necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice.
    Cardiovasc Res. 2023 Sep 15:cvad144. doi: 10.1093.
    PubMed     Abstract available

  5. SEIBERTZ F, Rubio T, Springer R, Popp F, et al
    Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development.
    Cardiovasc Res. 2023 Sep 7:cvad143. doi: 10.1093.
    PubMed     Abstract available

    July 2023
  6. BOURIER F, Schunkert H
    Has genetic disposition implications for treatment decisions in atrial fibrillation?
    Cardiovasc Res. 2023 Jul 5:cvad098. doi: 10.1093.

  7. MARCHAL GA, Galjart N, Portero V, Remme CA, et al
    Microtubule plus-end tracking proteins: novel modulators of cardiac sodium channels and arrhythmogenesis.
    Cardiovasc Res. 2023;119:1461-1479.
    PubMed     Abstract available

    June 2023
  8. KANY S, Al-Taie C, Roselli C, Pirruccello JP, et al
    Association of genetic risk and outcomes in patients with atrial fibrillation: interactions with early rhythm control in the EAST-AFNET4 trial.
    Cardiovasc Res. 2023 Jun 2:cvad027. doi: 10.1093.
    PubMed     Abstract available

    May 2023
  9. MORENO-MANUEL AI, Gutierrez LK, Vera-Pedrosa ML, Cruz FM, et al
    Molecular stratification of arrhythmogenic mechanisms in the Andersen Tawil syndrome.
    Cardiovasc Res. 2023;119:919-932.
    PubMed     Abstract available

    March 2023
  10. MCKAY M, Akar FG
    A unifying mechanism for the initiation of torsade de pointes: blurring the distinction between trigger and substrate.
    Cardiovasc Res. 2023;119:333-335.

  11. BOOGERD CJ, Lacraz GPA, Vertesy A, van Kampen SJ, et al
    Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy.
    Cardiovasc Res. 2023;119:477-491.
    PubMed     Abstract available

  12. CAMPOSTRINI G, Kosmidis G, Ward-van Oostwaard D, Davis RP, et al
    Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia.
    Cardiovasc Res. 2023;119:167-182.
    PubMed     Abstract available

  13. PARKSOOK WW, Williams GH
    Aldosterone and cardiovascular diseases.
    Cardiovasc Res. 2023;119:28-44.
    PubMed     Abstract available

    Large-scale digital population screening for atrial fibrillation: swinging around the uncertainties.
    Cardiovasc Res. 2023 Mar 3:cvad032. doi: 10.1093.

    January 2023
  15. NINNI S, Nattel S
    Factor XIa inhibition in atrial fibrillation: insights and knowledge gaps emerging from the PACIFIC-AF trial.
    Cardiovasc Res. 2023 Jan 25:cvac196. doi: 10.1093.

    December 2022
  16. GIACCA M
    Gene editing for cardiomyopathy takes a step forward.
    Cardiovasc Res. 2022;118:3011-3012.

  17. SUFFEE N, Baptista E, Piquereau J, Ponnaiah M, et al
    Impacts of a high-fat diet on the metabolic profile and the phenotype of atrial myocardium in mice.
    Cardiovasc Res. 2022;118:3126-3139.
    PubMed     Abstract available

    October 2022
  18. TOW BD, Deb A, Neupane S, Patel SM, et al
    SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release.
    Cardiovasc Res. 2022;118:2819-2832.
    PubMed     Abstract available

    July 2022
  19. NYNS ECA, Jin T, Fontes MS, van den Heuvel T, et al
    Optical ventricular cardioversion by local optogenetic targeting and LED implantation in a cardiomyopathic rat model.
    Cardiovasc Res. 2022;118:2293-2303.
    PubMed     Abstract available

  20. KEEFE J, Wehrens XH, Dobrev D
    Common disease-promoting signaling pathways in heart failure and atrial fibrillation: putative underlying mechanisms and potential therapeutic consequences.
    Cardiovasc Res. 2022 Jul 5. pii: 6631397. doi: 10.1093.

    June 2022
  21. CHAUMONT C, Suffee N, Gandjbakhch E, Balse E, et al
    Epicardial origin of cardiac arrhythmias: clinical evidences and pathophysiology.
    Cardiovasc Res. 2022;118:1693-1702.
    PubMed     Abstract available

  22. ALEXANDER C, Bishop MJ, Gilchrist RJ, MRes BA, et al
    Initiation of ventricular arrhythmia in the acquired long QT syndrome.
    Cardiovasc Res. 2022 Jun 21. pii: 6612700. doi: 10.1093.
    PubMed     Abstract available

  23. GAWALKO M, Saljic A, Li N, Abu-Taha I, et al
    Adiposity-associated atrial fibrillation: molecular determinants, mechanisms and clinical significance.
    Cardiovasc Res. 2022 Jun 11. pii: 6605797. doi: 10.1093.
    PubMed     Abstract available

    May 2022
  24. ROUHI L, Fan S, Cheedipudi SM, Braza-Boils A, et al
    The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure.
    Cardiovasc Res. 2022;118:1466-1478.
    PubMed     Abstract available

    April 2022
  25. LIUTKUTE A, Brundel BJ, Voigt N
    Not the classical serendipity: does doxapram treat atrial fibrillation?
    Cardiovasc Res. 2022 Apr 15. pii: 6568887. doi: 10.1093.

  26. FARINHA JM, Gupta D, Lip GYH
    Frequent premature atrial contractions as a signalling marker of atrial cardiomyopathy, incident atrial fibrillation and stroke.
    Cardiovasc Res. 2022 Apr 7. pii: 6564589. doi: 10.1093.
    PubMed     Abstract available

    March 2022
  27. YU JK, Liang JA, Franceschi WH, Huang Q, et al
    Assessment of arrhythmia mechanism and burden of the infarcted ventricles following remuscularization with pluripotent stem cell-derived cardiomyocyte patches using patient-derived models.
    Cardiovasc Res. 2022;118:1247-1261.
    PubMed     Abstract available

  28. PROIETTI R, Lip GYH, Akhtar R, Field M, et al
    Thoracic aortic aneurysms and atrial fibrillation: commonality in pathophysiological pathways.
    Cardiovasc Res. 2022;118:e32-e35.

  29. LOUCH WE
    A TRP to the emergency room: Understanding arrhythmia in the ageing heart.
    Cardiovasc Res. 2022;118:932-933.

  30. PEANA D, Polo-Parada L, Domeier TL
    Arrhythmogenesis in the aged heart following ischaemia-reperfusion: role of transient receptor potential vanilloid 4.
    Cardiovasc Res. 2022;118:1126-1137.
    PubMed     Abstract available

    January 2022
  31. MACIAS A, Diaz-Larrosa JJ, Blanco Y, Fanjul V, et al
    Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome.
    Cardiovasc Res. 2022;118:503-516.
    PubMed     Abstract available

  32. BARC J, Ravens U
    Scientists on the Spot: Tracing the potential in electrophysiology.
    Cardiovasc Res. 2022;118:e6-e7.

  33. JAYARAM R, Jones M, Reilly S, Crabtree MJ, et al
    Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: a randomized trial of atorvastatin.
    Cardiovasc Res. 2022;118:184-195.
    PubMed     Abstract available

  34. BORIANI G, Vitolo M, Diemberger I, Proietti M, et al
    Publisher's note to: Optimizing indices of atrial fibrillation susceptibility and burden to evaluate atrial fibrillation severity, risk and outcomes.
    Cardiovasc Res. 2022 Jan 5. pii: 6498023. doi: 10.1093.

    December 2021
  35. RAVENS U, Gomez AM, Heijman J, Remme CA, et al
    Edward Carmeliet (1930-2021)-channelling scientific curiosity: a tribute from the ESC Working Group on Cardiac Cellular Electrophysiologydagger.
    Cardiovasc Res. 2021;117:e171-e173.

  36. COPPINI R, Cerbai E
    Of hits, players, and goalkeepers: the case of arrhythmias in diabetes.
    Cardiovasc Res. 2021;117:2694-2695.

  37. HATEM SN, Cohen A
    Atrial fibrillation and stroke: are we looking in the right direction?
    Cardiovasc Res. 2021 Dec 13. pii: 6460256. doi: 10.1093.

    November 2021
  38. LI N, Durgan DJ, Wehrens XHT
    Gut microbiota - a key regulator of aging-associated atrial fibrillation?
    Cardiovasc Res. 2021 Nov 26. pii: 6443115. doi: 10.1093.
    PubMed     Abstract available

    October 2021
  39. SANTEMA BT, Arita VA, Sama IE, Kloosterman M, et al
    Pathophysiological pathways in patients with heart failure and atrial fibrillation.
    Cardiovasc Res. 2021 Oct 23. pii: 6409189. doi: 10.1093.
    PubMed     Abstract available

  40. NI L, Lahiri SK, Nie J, Pan X, et al
    Genetic inhibition of Nuclear Factor of Activated T-cell c2 (NFATc2) prevents atrial fibrillation in CREM transgenic mice.
    Cardiovasc Res. 2021 Oct 14. pii: 6396865. doi: 10.1093.
    PubMed     Abstract available

    September 2021
  41. DOBREV D, Dudley SC
    Oxidative stress: a bystander or a causal contributor to atrial remodelling and fibrillation?
    Cardiovasc Res. 2021;117:2291-2293.

  42. GAWALKO M, Agbaedeng TA, Saljic A, Muller DN, et al
    Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications.
    Cardiovasc Res. 2021 Sep 22. pii: 6373888. doi: 10.1093.
    PubMed     Abstract available

    August 2021
  43. CAMPBELL H, Aguilar-Sanchez Y, Quick AP, Dobrev D, et al
    SPEG: a key regulator of cardiac calcium homeostasis.
    Cardiovasc Res. 2021;117:2175-2185.
    PubMed     Abstract available

  44. BALLOUZ S, Mangala MM, Perry MD, Heitmann S, et al
    Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events.
    Cardiovasc Res. 2021;117:2216-2227.
    PubMed     Abstract available

  45. DING WY, McDowell G, Lip GYH
    Utilising biomarkers in atrial fibrillation: the pros and cons.
    Cardiovasc Res. 2021 Aug 25. pii: 6357701. doi: 10.1093.

  46. POL T, Hijazi Z, Lindback J, Oldgren J, et al
    Using multimarker screening to identify biomarkers associated with cardiovascular death in patients with atrial fibrillation.
    Cardiovasc Res. 2021 Aug 6. pii: 6343453. doi: 10.1093.
    PubMed     Abstract available

    July 2021
  47. HALL EJ, Pal S, Glennon MS, Shridhar P, et al
    Cardiac natriuretic peptide deficiency sensitizes the heart to stress induced ventricular arrhythmias via impaired CREB signaling.
    Cardiovasc Res. 2021 Jul 30. pii: 6332002. doi: 10.1093.
    PubMed     Abstract available

  48. AL SAYED ZR, Canac R, Cimarosti B, Bonnard C, et al
    Human model of IRX5 mutations reveals key role for this transcription factor in ventricular conduction.
    Cardiovasc Res. 2021;117:2092-2107.
    PubMed     Abstract available

  49. BOUKENS BJD, Dacey M, Meijborg VMF, Janse MJ, et al
    Mechanism of ventricular premature beats elicited by left stellate ganglion stimulation during acute ischaemia of the anterior left ventricle.
    Cardiovasc Res. 2021;117:2083-2091.
    PubMed     Abstract available

  50. ALVAREZ-FRANCO A, Rouco R, Ramirez RJ, Guerrero-Serna G, et al
    Erratum to: Transcriptome and proteome mapping in the sheep atria reveal molecular features of atrial fibrillation progression.
    Cardiovasc Res. 2021 Jul 13. pii: 6319837. doi: 10.1093.

  51. DERI S, Borbas J, Hartai T, Hategan L, et al
    Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient.
    Cardiovasc Res. 2021;117:1923-1934.
    PubMed     Abstract available

  52. RATHJENS FS, Blenkle A, Iyer LM, Renger A, et al
    Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control.
    Cardiovasc Res. 2021;117:1908-1922.
    PubMed     Abstract available

  53. ZHAO Y, James NA, Beshay AR, Chang EE, et al
    Adult zebrafish ventricular electrical gradients as tissue mechanisms of ECG patterns under baseline vs. oxidative stress.
    Cardiovasc Res. 2021;117:1891-1907.
    PubMed     Abstract available

    June 2021
    From translation to integration: how to approach the complexity of atrial fibrillation mechanisms.
    Cardiovasc Res. 2021;117:e88-e90.

  55. SCOTT L JR, Fender AC, Saljic A, Li L, et al
    NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias.
    Cardiovasc Res. 2021;117:1746-1759.
    PubMed     Abstract available

  56. HIRAM R, Xiong F, Naud P, Xiao J, et al
    The inflammation-resolution promoting molecule resolvin-D1 prevents atrial proarrhythmic remodelling in experimental right heart disease.
    Cardiovasc Res. 2021;117:1776-1789.
    PubMed     Abstract available

  57. BORIANI G, Vitolo M, Diemberger I, Proietti M, et al
    Optimizing indices of atrial fibrillation susceptibility and burden to evaluate atrial fibrillation severity, risk and outcomes.
    Cardiovasc Res. 2021;117:1-21.
    PubMed     Abstract available

  58. SANSONETTI M, De Windt LJ
    Non-coding RNAs in cardiac inflammation: key drivers in the pathophysiology of heart failure.
    Cardiovasc Res. 2021 Jun 7. pii: 6294284. doi: 10.1093.
    PubMed     Abstract available

  59. NATTEL S, Lip GYH, Filgueiras-Rama D, Dobrev D, et al
    Challenges and Opportunities in Improving the Management of Atrial Fibrillation: Recent Research Advances and their Clinical Translation.
    Cardiovasc Res. 2021 Jun 4. pii: 6292088. doi: 10.1093.

    May 2021
  60. CASADEI B, Sipido KR
    Calcium and postoperative atrial fibrillation: round up the usual suspects!
    Cardiovasc Res. 2021 May 29. pii: 6288489. doi: 10.1093.

  61. WIEDMANN F, Beyersdorf C, Zhou XB, Kraft M, et al
    Treatment of atrial fibrillation with doxapram: TASK-1 potassium channel inhibition as a novel pharmacological strategy.
    Cardiovasc Res. 2021 May 24. pii: 6283579. doi: 10.1093.
    PubMed     Abstract available

  62. HANNA P, Buch E, Stavrakis S, Meyer C, et al
    Neuroscientific Therapies for Atrial Fibrillation.
    Cardiovasc Res. 2021 May 14. pii: 6275748. doi: 10.1093.
    PubMed     Abstract available

  63. KANY S, Reissmann B, Metzner A, Kirchhof P, et al
    Genetics of atrial fibrillation - practical applications for clinical management: If not now, when and how?
    Cardiovasc Res. 2021 May 12. pii: 6274893. doi: 10.1093.
    PubMed     Abstract available

  64. OLIER I, Ortega-Martorell S, Pieroni M, Lip GYH, et al
    How machine learning is impacting research in atrial fibrillation: Implications for risk prediction and future management.
    Cardiovasc Res. 2021 May 12. pii: 6274894. doi: 10.1093.
    PubMed     Abstract available

    April 2021
  65. HEIJMAN J, Sutanto H, Crijns HJGM, Nattel S, et al
    Computational models of atrial fibrillation: achievements, challenges and perspectives for improving clinical care.
    Cardiovasc Res. 2021 Apr 23. pii: 6247759. doi: 10.1093.
    PubMed     Abstract available

  66. HATEM SN
    Revealing the molecular history of the transition from paroxysmal to permanent atrial fibrillation.
    Cardiovasc Res. 2021 Apr 20. pii: 6241493. doi: 10.1093.

    February 2021
  67. PROTONOTARIOS A, Marelli-Berg F
    Influenza-associated cardiac injury: a disease of the cardiac conduction system?
    Cardiovasc Res. 2021;117:643-644.

  68. LEE YK, Sala L, Mura M, Rocchetti M, et al
    MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes.
    Cardiovasc Res. 2021;117:767-779.
    PubMed     Abstract available

    January 2021
  69. HEGYI B, Ko CY, Bossuyt J, Bers DM, et al
    Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycemia: reduced repolarization reserve, neurohormonal stimulation and heart failure exacerbate susceptibility.
    Cardiovasc Res. 2021 Jan 23. pii: 6105172. doi: 10.1093.
    PubMed     Abstract available

  70. RONCHI C, Bernardi J, Mura M, Stefanello M, et al
    NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis.
    Cardiovasc Res. 2021;117:472-483.
    PubMed     Abstract available

  71. GUICHARD JB, Xiong F, Qi XY, L'Heureux N, et al
    Role of atrial arrhythmia and ventricular response in atrial fibrillation induced atrial remodelling.
    Cardiovasc Res. 2021;117:462-471.
    PubMed     Abstract available

    January 2020
  72. ZHANG D, Tu H, Wang C, Cao L, et al
    Inhibition of N-type calcium channels in cardiac sympathetic neurons attenuates ventricular arrhythmogenesis in heart failure.
    Cardiovasc Res. 2020 Jan 29. pii: 5717428. doi: 10.1093.
    PubMed     Abstract available

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