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Articles published in Clin Cardiol

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Single Articles


    October 2022
  1. YAMASHITA T, Kimura T, Ikemura N, Niimi N, et al
    Characteristics and health-status outcomes in patients with atrial fibrillation detected via health screening.
    Clin Cardiol. 2022 Oct 27. doi: 10.1002/clc.23932.
    PubMed     Abstract available


  2. SHEN Z, Chen D, Cheng H, Tan F, et al
    N-terminal pro-B-type natriuretic peptide and D-dimer combined with left atrial diameter to predict the risk of ischemic stroke in nonvalvular atrial fibrillation.
    Clin Cardiol. 2022 Oct 8. doi: 10.1002/clc.23933.
    PubMed     Abstract available


    September 2022
  3. LI X, Zhao C, Li M, Yu H, et al
    Predictive value of HMGB1 for atrial fibrillation recurrence after cryoballoon ablation in paroxysmal atrial fibrillation patients.
    Clin Cardiol. 2022 Sep 20. doi: 10.1002/clc.23904.
    PubMed     Abstract available


    August 2022
  4. YAN J, Liu M, Zhang Y, Yang D, et al
    Comparison of efficacy and safety between VKAs and DOACs in patients with atrial fibrillation after transcatheter aortic valve replacement: A systematic review and meta-analysis.
    Clin Cardiol. 2022 Aug 28. doi: 10.1002/clc.23909.
    PubMed     Abstract available


  5. PERINO AC, Fan J, Pundi K, Schmitt S, et al
    Atrial fibrillation bleeding risk and prediction while treated with direct oral anticoagulants in warfarin-naive or warfarin-experienced patients.
    Clin Cardiol. 2022 Aug 9. doi: 10.1002/clc.23887.
    PubMed     Abstract available


  6. ZHANG K, Zhou J, Zhang T, Zhang Z, et al
    Comparison of multiple imaging modalities for measuring orifice diameter and selecting occluder size in patients undergoing left atrial appendage closure.
    Clin Cardiol. 2022;45:864-872.
    PubMed     Abstract available


    July 2022
  7. ECKSTEIN J, Renner A, Zittermann A, Fink T, et al
    Impact of left atrial appendage fibrosis on atrial fibrillation in patients following coronary bypass surgery.
    Clin Cardiol. 2022 Jul 21. doi: 10.1002/clc.23884.
    PubMed     Abstract available


    June 2022
  8. NARLA VA, Yang H, Li Q
    Outcomes of implantable cardioverter-defibrillator implantation in HIV-infected patients: A single-center retrospective cohort study.
    Clin Cardiol. 2022 Jun 1. doi: 10.1002/clc.23868.
    PubMed     Abstract available


  9. SOLIMENE F, Stabile G, Ramos P, Segreti L, et al
    Improved procedural workflow for catheter ablation of paroxysmal AF with high-density mapping system and advanced technology: Rationale and study design of a multicenter international study.
    Clin Cardiol. 2022;45:597-604.
    PubMed     Abstract available


  10. BILLER K, Biller B, Findeisen H, Eckardt L, et al
    Resolution of left atrial appendage thrombi: No difference between phenprocoumon and non-vitamin K-dependent oral antagonists.
    Clin Cardiol. 2022;45:650-656.
    PubMed     Abstract available


  11. MOSTAFA MR, Magdi M, Al-Abdouh A, Abusnina W, et al
    A systematic review and meta-analysis of the impact of the left atrial appendage closure on left atrial function.
    Clin Cardiol. 2022;45:614-621.
    PubMed     Abstract available


    May 2022
  12. GU G, Wu J, Gao X, Liu M, et al
    Catheter ablation of atrial fibrillation in patients with heart failure and preserved ejection fraction: A meta-analysis.
    Clin Cardiol. 2022 May 11. doi: 10.1002/clc.23841.
    PubMed     Abstract available


  13. KOTRUCHIN P, Chaiyakhan IO, Kamonsri P, Chantapoh W, et al
    Comparison between the double-syringe and the single-syringe techniques of adenosine administration for terminating supraventricular tachycardia: A pilot, randomized controlled trial.
    Clin Cardiol. 2022;45:583-589.
    PubMed     Abstract available


  14. ASVESTAS D, Sousonis V, Kotsovolis G, Karanikas S, et al
    Cavotricuspid isthmus ablation guided by force-time integral - A randomized study.
    Clin Cardiol. 2022;45:503-508.
    PubMed     Abstract available


    March 2022
  15. STOHR R, Dirrichs T, Kneizeh K, Reinartz S, et al
    Influence of rivaroxaban compared to vitamin K antagonist treatment upon development of cardiovascular calcification in patients with atrial fibrillation and/or pulmonary embolism.
    Clin Cardiol. 2022 Mar 25. doi: 10.1002/clc.23819.
    PubMed     Abstract available


  16. HOU J, Sun Y, Zhang L, Wang W, et al
    Assessing left atrial function in patients with atrial fibrillation and valvular heart disease using cardiovascular magnetic resonance imaging.
    Clin Cardiol. 2022 Mar 15. doi: 10.1002/clc.23811.
    PubMed     Abstract available


  17. SUN L, Zhou M, Ji Y, Wang X, et al
    Off-pump versus on-pump coronary artery bypass grafting for octogenarians: A meta-analysis involving 146 372 patients.
    Clin Cardiol. 2022 Mar 10. doi: 10.1002/clc.23794.
    PubMed     Abstract available


  18. WANG G, Zhao N, Zhong S, Wang H, et al
    Association of early repolarization pattern and ventricular fibrillation in patients with vasospastic angina: A systematic review and meta-analysis.
    Clin Cardiol. 2022 Mar 7. doi: 10.1002/clc.23804.
    PubMed     Abstract available


  19. XUE L, Yang YC, Zhao Q, Zhao ZH, et al
    The spectrum and prevalence of arrhythmia in different clinical pulmonary hypertension groups in Chinese population.
    Clin Cardiol. 2022 Mar 7. doi: 10.1002/clc.23803.
    PubMed     Abstract available


  20. LAUFER-PERL M, Sadon S, Zahler D, Milwidsky A, et al
    Repetitive milrinone therapy in ambulatory advanced heart failure patients.
    Clin Cardiol. 2022 Mar 4. doi: 10.1002/clc.23802.
    PubMed     Abstract available


  21. KELLNAR A, Fichtner S, Mehr M, Czermak T, et al
    Single-center experience of ultra-high-density mapping guided catheter ablation of focal atrial tachycardia.
    Clin Cardiol. 2022;45:291-298.
    PubMed     Abstract available


    February 2022
  22. LUO Q, Xie Y, Bao Y, Wei Y, et al
    Utilization of steerable sheath improves the efficiency of atrial fibrillation ablation guided by robotic magnetic navigation compared with fixed-curve sheath.
    Clin Cardiol. 2022 Feb 23. doi: 10.1002/clc.23801.
    PubMed     Abstract available


  23. CHEN YF, Liu F, Li XW, Zhang HJ, et al
    Non-vitamin K oral anticoagulants versus vitamin K antagonists in post transcatheter aortic valve replacement patients with clinical indication for oral anticoagulation: A meta-analysis.
    Clin Cardiol. 2022 Feb 22. doi: 10.1002/clc.23793.
    PubMed     Abstract available


  24. KRITTAYAPHONG R, Pumprueg S, Sairat P
    Soluble ST2 in the prediction of heart failure and death in patients with atrial fibrillation.
    Clin Cardiol. 2022 Feb 21. doi: 10.1002/clc.23799.
    PubMed     Abstract available


  25. PRASITLUMKUM N, Chokesuwattanaskul R, Kaewput W, Thongprayoon C, et al
    Utilization and in-hospital complications of catheter ablation for atrial fibrillation in patients with obesity and morbid obesity.
    Clin Cardiol. 2022 Feb 16. doi: 10.1002/clc.23795.
    PubMed     Abstract available


  26. ALIREZAEI T, Mahboubi-Fooladi Z, Irilouzadian R, Saberi Shahrbabaki A, et al
    CHA2 DS2 -VASc and PESI scores are associated with right ventricular dysfunction on computed tomography pulmonary angiography in patients with acute pulmonary thromboembolism.
    Clin Cardiol. 2022;45:224-230.
    PubMed     Abstract available


    January 2022
  27. RASHEDI S, Tavolinejad H, Kazemian S, Mardani M, et al
    Efficacy and safety of same-day discharge after atrial fibrillation ablation: A systematic review and meta-analysis.
    Clin Cardiol. 2022 Jan 27. doi: 10.1002/clc.23778.
    PubMed     Abstract available


  28. SANG DS, Zhang Q, Song D, Tao J, et al
    Association between brachial-ankle pulse wave velocity and cardiovascular and cerebrovascular disease in different age groups.
    Clin Cardiol. 2022 Jan 23. doi: 10.1002/clc.23777.
    PubMed     Abstract available


  29. DU H, Yang L, Hu Z, Zhang H, et al
    Anxiety is associated with higher recurrence of atrial fibrillation after catheter ablation: A meta-analysis.
    Clin Cardiol. 2022 Jan 18. doi: 10.1002/clc.23753.
    PubMed     Abstract available


  30. THIND M, McKindley DS, Reiffel JA, Naccarelli GV, et al
    Predictors of dronedarone plasma drug concentrations and effect on atrial fibrillation/atrial flutter recurrence: Analyses from the EURIDIS and ADONIS studies.
    Clin Cardiol. 2022 Jan 15. doi: 10.1002/clc.23768.
    PubMed     Abstract available


  31. THIND M, Zareba W, Atar D, Crijns HJGM, et al
    Efficacy and safety of dronedarone versus placebo in patients with atrial fibrillation stratified according to renal function: Post hoc analyses of the EURIDIS-ADONIS trials.
    Clin Cardiol. 2022 Jan 12. doi: 10.1002/clc.23765.
    PubMed     Abstract available


  32. MAHMOUDI E, Mollazadeh R, Mansouri P, Keykhaei M, et al
    Ventricular repolarization heterogeneity in patients with COVID-19: Original data, systematic review, and meta-analysis.
    Clin Cardiol. 2022;45:110-118.
    PubMed     Abstract available


    December 2021
  33. ZHANG Z, Jiang C, He L, Bai Y, et al
    Associations of anemia with death and major bleeding in patients with atrial fibrillation: A report from the Chinese Atrial Fibrillation Registry Study.
    Clin Cardiol. 2021 Dec 28. doi: 10.1002/clc.23764.
    PubMed     Abstract available


  34. ZHAO X, Li H, Liu C, Ren Y, et al
    NT Pro-BNP can be used as a risk predictor of clinical atrial fibrillation with or without left atrial enlargement.
    Clin Cardiol. 2021 Dec 24. doi: 10.1002/clc.23760.
    PubMed     Abstract available


  35. WANG JR, Du X, Dong JZ, Chang SS, et al
    Use of oral anticoagulants and its associated factors among nonvalvular atrial fibrillation patients with new-onset acute ischemic stroke: A report from the China Atrial Fibrillation Registry study.
    Clin Cardiol. 2021 Dec 24. doi: 10.1002/clc.23759.
    PubMed     Abstract available


  36. WALFRIDSSON U, Hassel Jonsson A, Karlsson LO, Liuba I, et al
    Symptoms and health-related quality of life 5 years after catheter ablation of atrial fibrillation.
    Clin Cardiol. 2021 Dec 16. doi: 10.1002/clc.23752.
    PubMed     Abstract available


    November 2021
  37. SIMON J, El Mahdiui M, Smit JM, Szaraz L, et al
    Left atrial appendage size is a marker of atrial fibrillation recurrence after radiofrequency catheter ablation in patients with persistent atrial fibrillation.
    Clin Cardiol. 2021 Nov 19. doi: 10.1002/clc.23748.
    PubMed     Abstract available


  38. LEE S, Jeevaratnam K, Liu T, Chang D, et al
    Risk stratification of cardiac arrhythmias and sudden cardiac death in type 2 diabetes mellitus patients receiving insulin therapy: A population-based cohort study.
    Clin Cardiol. 2021;44:1602-1612.
    PubMed     Abstract available


    October 2021
  39. VONDERLIN N, Kortuem K, Siebermair J, Kohrmann M, et al
    Central retinal artery occlusion as a first sign of atrial fibrillation: A 3-year retrospective single-center analysis.
    Clin Cardiol. 2021 Oct 28. doi: 10.1002/clc.23673.
    PubMed     Abstract available


  40. STRAUBE F, Pongratz J, Hartl S, Brueck B, et al
    Cardiac computed tomography angiography-derived analysis of left atrial appendage morphology and left atrial dimensions for the prediction of atrial fibrillation recurrence after pulmonary vein isolation.
    Clin Cardiol. 2021 Oct 14. doi: 10.1002/clc.23743.
    PubMed     Abstract available


  41. POMMIER T, Guenancia C, Richard C, Sagnard A, et al
    Safety and efficacy of left atrial appendage occlusion with the ACP or Watchman device guided by intracardiac echocardiography from the left atrium.
    Clin Cardiol. 2021;44:1402-1408.
    PubMed     Abstract available


  42. GLIBBERY M, Banks L, Altaha MA, Bentley RF, et al
    Atrial structure and function in middle-aged, physically-active males and females: A cardiac magnetic resonance study.
    Clin Cardiol. 2021;44:1467-1474.
    PubMed     Abstract available


  43. HOSSEINI Z, Mollazadeh R, Dehghan-Manshadi SA, Mohebi M, et al
    Association between exposure to Efavirenz and substrates of dysrhythmia in HIV-infected young adults.
    Clin Cardiol. 2021;44:1448-1456.
    PubMed     Abstract available


    September 2021
  44. LI L, Selvin E, Hoogeveen RC, Soliman EZ, et al
    6-year change in high sensitivity cardiac troponin T and the risk of atrial fibrillation in the Atherosclerosis Risk in Communities cohort.
    Clin Cardiol. 2021 Sep 21. doi: 10.1002/clc.23727.
    PubMed     Abstract available


  45. SEEWOSTER T, Dinov B, Nedios S, Hindricks G, et al
    Biatrial volume ratio predicts low voltage areas in atrial fibrillation.
    Clin Cardiol. 2021 Sep 8. doi: 10.1002/clc.23720.
    PubMed     Abstract available


  46. HE G, Liu H, Huang X, Deng X, et al
    Intracardiac versus transesophageal echocardiography for diagnosis of left atrial appendage thrombosis in atrial fibrillation: A meta-analysis.
    Clin Cardiol. 2021 Sep 3. doi: 10.1002/clc.23698.
    PubMed     Abstract available


  47. CHRISTOPH M, Youssef A, Svitil J, Forkmann M, et al
    Comparison of uninterrupted direct oral anticoagulation with vitamin-K antagonists during AF-ablation in the clinical routine. A single center register.
    Clin Cardiol. 2021;44:1243-1248.
    PubMed     Abstract available


    August 2021
  48. XIANG B, Ma W, Yan S, Chen J, et al
    Rhythm outcomes after aortic valve surgery: Treatment and evolution of new-onset atrial fibrillation.
    Clin Cardiol. 2021 Aug 14. doi: 10.1002/clc.23703.
    PubMed     Abstract available


  49. MIAO Y, Xu M, Zhang C, Liu H, et al
    An echocardiographic model for predicting the recurrence of paroxysmal atrial fibrillation after circumferential pulmonary vein ablation.
    Clin Cardiol. 2021 Aug 11. doi: 10.1002/clc.23712.
    PubMed     Abstract available


  50. ZELJKOVIC I, Brusich S, Scherr D, Velagic V, et al
    Differences in activated clotting time and total unfractionated heparin dose during pulmonary vein isolation in patients on different anticoagulation therapy.
    Clin Cardiol. 2021;44:1177-1182.
    PubMed     Abstract available


  51. D'SOUZA S, Elshazly MB, Dargham SR, Donnellan E, et al
    Atrial fibrillation catheter ablation complications in obese and diabetic patients: Insights from the US Nationwide Inpatient Sample 2005-2013.
    Clin Cardiol. 2021;44:1151-1160.
    PubMed     Abstract available


    July 2021
  52. BARKAS F, Bechlioulis A, Liberopoulos E
    Bradycardia and coronavirus disease 2019: What is behind?
    Clin Cardiol. 2021 Jul 30. doi: 10.1002/clc.23701.
    PubMed    


  53. MAO YJ, Feng WY, Huang QY, Yu FL, et al
    Meta-analysis of cryoballoon ablation versus antiarrhythmic drugs as initial therapy for symptomatic atrial fibrillation.
    Clin Cardiol. 2021 Jul 29. doi: 10.1002/clc.23695.
    PubMed     Abstract available


  54. KUMAR S, Arcuri C, Chaudhuri S, Gupta R, et al
    Remdesivir therapy associated with Bradycardia in SARS-CoV2.
    Clin Cardiol. 2021 Jul 28. doi: 10.1002/clc.23700.
    PubMed    


  55. WATANABE E, Noyama S, Kiyono K, Inoue H, et al
    Comparison among random forest, logistic regression, and existing clinical risk scores for predicting outcomes in patients with atrial fibrillation: A report from the J-RHYTHM registry.
    Clin Cardiol. 2021 Jul 28. doi: 10.1002/clc.23688.
    PubMed     Abstract available


  56. CUI YK, Dong JZ, Du X, Hu R, et al
    Comparison of prognosis and outcomes of catheter ablation versus drug therapy in patients with atrial fibrillation and stable coronary artery disease: A prospective propensity-score matched cohort study.
    Clin Cardiol. 2021 Jul 28. doi: 10.1002/clc.23699.
    PubMed     Abstract available


  57. JIANG H, Jiang Y, Ma H, Zeng H, et al
    Effects of rivaroxaban and warfarin on the risk of gastrointestinal bleeding and intracranial hemorrhage in patients with atrial fibrillation: Systematic review and meta-analysis.
    Clin Cardiol. 2021 Jul 24. doi: 10.1002/clc.23690.
    PubMed     Abstract available


  58. SUNAGA A, Masuda M, Inoue K, Tanaka N, et al
    The efficacy and safety of left atrial low-voltage area guided ablation for recurrence prevention compared to pulmonary vein isolation alone in patients with persistent atrial fibrillation trial: Design and rationale.
    Clin Cardiol. 2021 Jul 22. doi: 10.1002/clc.23677.
    PubMed     Abstract available


  59. KUMAR S, Arcuri C, Chaudhuri S, Gupta R, et al
    Response to Dr. Masaya Miyauchi and Dr. Teruhiko Imamura, Clinical implication of COVID-19 associated bradycardia.
    Clin Cardiol. 2021 Jul 9. doi: 10.1002/clc.23675.
    PubMed    


    June 2021
  60. ZHU J, Tan X, Zhou JZ
    Peripheral artery disease and clinical outcomes in patients with atrial fibrillation: A systematic review and meta-analysis.
    Clin Cardiol. 2021 Jun 25. doi: 10.1002/clc.23678.
    PubMed     Abstract available


  61. SAWASAKI K, Inden Y, Hosoya N, Muto M, et al
    Defibrillation threshold of internal cardioversion prior to ablation predicts atrial fibrillation recurrence.
    Clin Cardiol. 2021 Jun 23. doi: 10.1002/clc.23679.
    PubMed     Abstract available


  62. MIYAUCHI M, Imamura T
    Clinical implication of COVID-19 associated bradycardia.
    Clin Cardiol. 2021 Jun 19. doi: 10.1002/clc.23674.
    PubMed    


  63. DONG Z, Du X, Hou XX, He L, et al
    Effect of electrical cardioversion on 1-year outcomes in patients with early recurrence after catheter ablation for atrial fibrillation.
    Clin Cardiol. 2021 Jun 8. doi: 10.1002/clc.23663.
    PubMed     Abstract available


  64. WANG W, Chen Q, Zhang F, Chen X, et al
    Radiofrequency catheter ablation combined with spironolactone in the treatment of atrial fibrillation: A single-center randomized controlled study.
    Clin Cardiol. 2021 Jun 2. doi: 10.1002/clc.23659.
    PubMed     Abstract available


  65. HOU Q, Feng L, Yang J, Liu Y, et al
    The immediate trends in atrial electrical remodeling for paroxysmal atrial fibrillation across different modes of catheter ablation.
    Clin Cardiol. 2021 Jun 1. doi: 10.1002/clc.23617.
    PubMed     Abstract available


  66. LU WD, Chen JY
    The optimal cutoff of atrial high-rate episodes for neurological events in patients with dual chamber permanent pacemakers.
    Clin Cardiol. 2021;44:871-879.
    PubMed     Abstract available


  67. CHIANG LLW, Li C, Hong KL, Hui WS, et al
    The use of minimal fluoroscopy for cardiac electrophysiology procedures: A meta-analysis and review of the literature.
    Clin Cardiol. 2021;44:814-823.
    PubMed     Abstract available


  68. LIN J, Qian Y, Chen Q, Zhang M, et al
    The burden of premature ventricular contractions predicts adverse fetal and neonatal outcomes among pregnant women without structural heart disease: A prospective cohort study.
    Clin Cardiol. 2021;44:833-838.
    PubMed     Abstract available


  69. LI S, Deng Y, Tong Y, Xiong Q, et al
    Assessment of non-vitamin K antagonist oral anticoagulants for the management of left ventricular thrombus.
    Clin Cardiol. 2021;44:754-760.
    PubMed     Abstract available


    May 2021
  70. ECCLESTON DS, Kim JM, Ten Berg JM, Steg PG, et al
    The effect of sex on the efficacy and safety of dual antithrombotic therapy with dabigatran versus triple therapy with warfarin after PCI in patients with atrial fibrillation (a RE-DUAL PCI subgroup analysis and comparison to other dual antithrombotic
    Clin Cardiol. 2021 May 27. doi: 10.1002/clc.23649.
    PubMed     Abstract available


  71. GUO Z, Ding X, Ye Z, Chen W, et al
    Non-vitamin K antagonist oral anticoagulants versus vitamin K antagonists in atrial fibrillation patients with previous stroke or intracranial hemorrhage: A systematic review and meta-analysis of observational studies.
    Clin Cardiol. 2021 May 20. doi: 10.1002/clc.23647.
    PubMed     Abstract available


  72. KUMAR S, Arcuri C, Chaudhuri S, Gupta R, et al
    A novel study on SARS-COV-2 virus associated bradycardia as a predictor of mortality-retrospective multicenter analysis.
    Clin Cardiol. 2021 May 8. doi: 10.1002/clc.23622.
    PubMed     Abstract available


    April 2021
  73. NIE C, Zhu C, Xiao M, Yang Q, et al
    Mid-ventricular obstruction is associated with non-sustained ventricular tachycardia in patients with hypertrophic obstructive cardiomyopathy.
    Clin Cardiol. 2021;44:555-562.
    PubMed     Abstract available


  74. YAMAMOTO T, Iwasaki YK, Fujimoto Y, Oka E, et al
    The characteristics and efficacy of catheter ablation of focal atrial tachycardia arising from an epicardial site.
    Clin Cardiol. 2021;44:563-572.
    PubMed     Abstract available


    March 2021
  75. NARLA VA
    Sudden cardiac death in HIV-infected patients: A contemporary review.
    Clin Cardiol. 2021;44:316-321.
    PubMed     Abstract available


    January 2021
  76. ABUDAN AA, Vaidya VR, Tripathi B, Noseworthy PA, et al
    Burden of arrhythmia in hospitalized HIV patients.
    Clin Cardiol. 2021;44:66-77.
    PubMed     Abstract available


  77. KOSIUK J, Fiedler L, Ernst S, Duncker D, et al
    Fluoroscopy usage in contemporary interventional electrophysiology: Insights from a European registry.
    Clin Cardiol. 2021;44:36-42.
    PubMed     Abstract available


    October 2020
  78. CHENG YJ, Zhao XX, Pan SP, Pan JM, et al
    Association of early repolarization pattern with cardiovascular outcomes in middle-aged population: A cohort study.
    Clin Cardiol. 2020 Oct 26. doi: 10.1002/clc.23488.
    PubMed     Abstract available


    September 2020
  79. ELZENEINI M, Assaf Y, Aalaei-Andabili SH, Mahmoud A, et al
    Predictors of ventricular pacing burden after permanent pacemaker implantation following transcatheter aortic valve replacement.
    Clin Cardiol. 2020 Sep 4. doi: 10.1002/clc.23447.
    PubMed     Abstract available


    May 2020
  80. GOTZMANN M, Choudhury DS, Hogeweg M, Heringhaus F, et al
    Risk stratification in patients undergoing interventional left atrial appendage occlusion-Prognostic impact of EuroSCORE II.
    Clin Cardiol. 2020;43:508-515.
    PubMed     Abstract available


  81. CHEN CF, Zhong YG, Jin CL, Gao XF, et al
    Comparing between second-generation cryoballoon vs open-irrigated radiofrequency ablation in elderly patients: Acute and long-term outcomes.
    Clin Cardiol. 2020;43:500-507.
    PubMed     Abstract available


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