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Articles published in Brain

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    May 2020
  1. RAMBERGER M, Berretta A, Tan JMM, Sun B, et al
    Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms.
    Brain. 2020 May 21. pii: 5841730. doi: 10.1093.
    PubMed     Abstract available


  2. FRANSEN NL, Hsiao CC, van der Poel M, Engelenburg HJ, et al
    Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions.
    Brain. 2020 May 13. pii: 5836675. doi: 10.1093.
    PubMed     Abstract available


  3. MALPAS CB, Manouchehrinia A, Sharmin S, Roos I, et al
    Early clinical markers of aggressive multiple sclerosis.
    Brain. 2020 May 9. pii: 5835340. doi: 10.1093.
    PubMed     Abstract available


  4. KADOWAKI A, Quintana FJ
    The NLRP3 inflammasome in progressive multiple sclerosis.
    Brain. 2020;143:1286-1288.
    PubMed    


    April 2020
  5. DIETRICH M, Koska V, Hecker C, Gottle P, et al
    Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
    Brain. 2020 Apr 15. pii: 5820386. doi: 10.1093.
    PubMed     Abstract available


  6. MALHOTRA S, Costa C, Eixarch H, Keller CW, et al
    NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
    Brain. 2020 Apr 13. pii: 5819591. doi: 10.1093.
    PubMed     Abstract available


    March 2020
  7. KLEEREKOOPER I, Petzold A, Trip SA
    Anterior visual system imaging to investigate energy failure in multiple sclerosis.
    Brain. 2020 Mar 12. pii: 5804129. doi: 10.1093.
    PubMed     Abstract available


    November 2019
  8. MEIJER KA, Steenwijk MD, Douw L, Schoonheim MM, et al
    Long-range connections are more severely damaged and relevant for cognition in multiple sclerosis.
    Brain. 2019 Nov 15. pii: 5626204. doi: 10.1093.
    PubMed     Abstract available


    October 2019
  9. HAUSLER D, Torke S, Peelen E, Bertsch T, et al
    Reply: Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis.
    Brain. 2019 Oct 30. pii: 5610115. doi: 10.1093.
    PubMed    


  10. SMOLDERS J, Damoiseaux J, Hupperts R
    Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis.
    Brain. 2019 Oct 30. pii: 5610116. doi: 10.1093.
    PubMed    


  11. SABBAGH S, Almeida de Jesus A, Hwang S, Kuehn HS, et al
    Treatment of anti-MDA5 autoantibody-positive juvenile dermatomyositis using tofacitinib.
    Brain. 2019 Oct 11. pii: 5585662. doi: 10.1093.
    PubMed    


  12. LANDON-CARDINAL O, Benveniste O, Allenbach Y
    Reply: Treatment of anti-MDA5 autoantibody-positive juvenile dermatomyositis using tofacitinib.
    Brain. 2019 Oct 11. pii: 5585663. doi: 10.1093.
    PubMed    


  13. CRISP SJ, Dixon CL, Jacobson L, Chabrol E, et al
    Glycine receptor autoantibodies disrupt inhibitory neurotransmission.
    Brain. 2019 Oct 8. pii: 5583666. doi: 10.1093.
    PubMed     Abstract available


  14. NUTMA E, Stephenson JA, Gorter RP, de Bruin J, et al
    A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis.
    Brain. 2019 Oct 3. pii: 5580333. doi: 10.1093.
    PubMed     Abstract available


  15. KARAKAYA M, Wirth B
    Hereditary nodo-paranodopathies: genomic variants, not just autoantibodies, hit the protein.
    Brain. 2019;142:2895-2897.
    PubMed    


    September 2019
  16. ELLIOTT C, Belachew S, Wolinsky JS, Hauser SL, et al
    Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis.
    Brain. 2019;142:2787-2799.
    PubMed     Abstract available


  17. PENNER IK, Hartung HP
    The dark side of the moon: looking beyond beneficial effects of cannabis use in multiple sclerosis.
    Brain. 2019;142:2552-2555.
    PubMed    


  18. BENVENISTE O, Allenbach Y
    Inclusion body myositis: accumulation of evidence for its autoimmune origin.
    Brain. 2019;142:2549-2551.
    PubMed    


    August 2019
  19. MORQUETTE B, Juzwik CA, Drake SS, Charabati M, et al
    MicroRNA-223 protects neurons from degeneration in experimental autoimmune encephalomyelitis.
    Brain. 2019 Aug 14. pii: 5549993. doi: 10.1093.
    PubMed     Abstract available


  20. BROWNLEE WJ, Altmann DR, Prados F, Miszkiel KA, et al
    Early imaging predictors of long-term outcomes in relapse-onset multiple sclerosis.
    Brain. 2019;142:2276-2287.
    PubMed     Abstract available


    July 2019
  21. FEINSTEIN A, Meza C, Stefan C, Staines RW, et al
    Coming off cannabis: a cognitive and magnetic resonance imaging study in patients with multiple sclerosis.
    Brain. 2019 Jul 30. pii: 5541023. doi: 10.1093.
    PubMed     Abstract available


  22. WENTLING M, Lopez-Gomez C, Park HJ, Amatruda M, et al
    A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis.
    Brain. 2019 Jul 15. pii: 5531715. doi: 10.1093.
    PubMed     Abstract available


  23. HAUSLER D, Torke S, Peelen E, Bertsch T, et al
    High dose vitamin D exacerbates central nervous system autoimmunity by raising T-cell excitatory calcium.
    Brain. 2019 Jul 13. pii: 5532100. doi: 10.1093.
    PubMed     Abstract available


  24. FITZGERALD KC, Kim K, Smith MD, Aston SA, et al
    Early complement genes are associated with visual system degeneration in multiple sclerosis.
    Brain. 2019 Jul 9. pii: 5530228. doi: 10.1093.
    PubMed     Abstract available


  25. ROPELE S, Fazekas F
    Quantification of cortical damage in multiple sclerosis using DTI remains a challenge.
    Brain. 2019;142:1848-1850.
    PubMed    


    June 2019
  26. FILIPPI M, Preziosa P, Banwell BL, Barkhof F, et al
    Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
    Brain. 2019 Jun 17. pii: 5519813. doi: 10.1093.
    PubMed     Abstract available


  27. PREZIOSA P, Kiljan S, Steenwijk MD, Meani A, et al
    Axonal degeneration as substrate of fractional anisotropy abnormalities in multiple sclerosis cortex.
    Brain. 2019 Jun 5. pii: 5511700. doi: 10.1093.
    PubMed     Abstract available


    May 2019
  28. MUNK NIELSEN N, Corn G, Frisch M, Stenager E, et al
    Multiple sclerosis among first- and second-generation immigrants in Denmark: a population-based cohort study.
    Brain. 2019 May 13. pii: 5488579. doi: 10.1093.
    PubMed     Abstract available


  29. COTZOMI E, Stathopoulos P, Lee CS, Ritchie AM, et al
    Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production.
    Brain. 2019 May 5. pii: 5485817. doi: 10.1093.
    PubMed     Abstract available


  30. GIOVANNONI G
    Survival: the ultimate long-term outcome in multiple sclerosis.
    Brain. 2019;142:1166-1167.
    PubMed    


  31. PALACE J, Lin DY, Zeng D, Majed M, et al
    Outcome prediction models in AQP4-IgG positive neuromyelitis optica spectrum disorders.
    Brain. 2019;142:1310-1323.
    PubMed     Abstract available


    April 2019
  32. VAN COEVORDEN-HAMEETE MH, de Bruijn MAAM, de Graaff E, Bastiaansen DAEM, et al
    The expanded clinical spectrum of anti-GABABR encephalitis and added value of KCTD16 autoantibodies.
    Brain. 2019 Apr 22. pii: 5476117. doi: 10.1093.
    PubMed     Abstract available


  33. WEKERLE H
    Secondary progressive multiple sclerosis and the gut-brain axis.
    Brain. 2019;142:838-840.
    PubMed    


    March 2019
  34. KINGWELL E, Leray E, Zhu F, Petkau J, et al
    Multiple sclerosis: effect of beta interferon treatment on survival.
    Brain. 2019 Mar 18. pii: 5382233. doi: 10.1093.
    PubMed     Abstract available


  35. HOHLFELD R
    Immune dysbalance in childhood multiple sclerosis: a 'chicken or the egg' conundrum.
    Brain. 2019;142:490-492.
    PubMed    


    February 2019
  36. KADOWAKI A, Saga R, Lin Y, Sato W, et al
    Gut microbiota-dependent CCR9+CD4+ T cells are altered in secondary progressive multiple sclerosis.
    Brain. 2019 Feb 15. pii: 5321131. doi: 10.1093.
    PubMed     Abstract available


  37. MEXHITAJ I, Nyirenda MH, Li R, O'Mahony J, et al
    Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis.
    Brain. 2019 Feb 12. pii: 5316384. doi: 10.1093.
    PubMed     Abstract available


  38. ALLENBACH Y, Bolko L, Toquet S, Landon-Cardinal O, et al
    Reply: Janus kinase 1/2 inhibition with baricitinib in the treatment of juvenile dermatomyositis.
    Brain. 2019 Feb 1. pii: 5305679. doi: 10.1093.
    PubMed    


  39. PAPADOPOULOU C, Hong Y, Omoyinmi E, Brogan PA, et al
    Janus kinase 1/2 inhibition with baricitinib in the treatment of juvenile dermatomyositis.
    Brain. 2019 Feb 1. pii: 5305681. doi: 10.1093.
    PubMed    


    January 2019
  40. EDEN D, Gros C, Badji A, Dupont SM, et al
    Spatial distribution of multiple sclerosis lesions in the cervical spinal cord.
    Brain. 2019 Jan 30. pii: 5304670. doi: 10.1093.
    PubMed     Abstract available


  41. NTRANOS A, Ntranos V, Bonnefil V, Liu J, et al
    Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis.
    Brain. 2019 Jan 28. pii: 5303708. doi: 10.1093.
    PubMed     Abstract available


  42. CHEN Y, Podojil JR, Kunjamma RB, Jones J, et al
    Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis.
    Brain. 2019 Jan 17. pii: 5289373. doi: 10.1093.
    PubMed     Abstract available


    December 2018
  43. VON ESSEN MR, Ammitzboll C, Hansen RH, Petersen ERS, et al
    Proinflammatory CD20+ T cells in the pathogenesis of multiple sclerosis.
    Brain. 2018 Dec 17. pii: 5250831. doi: 10.1093.
    PubMed     Abstract available


  44. KAUNZNER UW, Kang Y, Zhang S, Morris E, et al
    Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions.
    Brain. 2018 Dec 15. pii: 5250435. doi: 10.1093.
    PubMed     Abstract available


    November 2018
  45. ZALC B
    One hundred and fifty years ago Charcot reported multiple sclerosis as a new neurological disease.
    Brain. 2018 Nov 20. pii: 5194497. doi: 10.1093.
    PubMed    


  46. ALY L, Korn T
    Multiple sclerosis: is it all black and white in optical coherence tomography?
    Brain. 2018;141:3088-3091.
    PubMed    


  47. DEBANNE D, El Far O
    Pre- and postsynaptic effects of LGI1 autoantibodies in a murine model of limbic encephalitis.
    Brain. 2018;141:3092-3095.
    PubMed    


  48. AESCHLIMANN FA, Fremond ML, Duffy D, Rice GI, et al
    A child with severe juvenile dermatomyositis treated with ruxolitinib.
    Brain. 2018;141:e80.
    PubMed    


  49. ALLENBACH Y, Toquet S, Landon-Cardinal O, Benveniste O, et al
    Reply: A child with severe juvenile dermatomyositis treated with ruxolitinib.
    Brain. 2018;141:e81.
    PubMed    


    October 2018
  50. CALDITO NG, Saidha S, Sotirchos ES, Dewey BE, et al
    Brain and retinal atrophy in African-Americans versus Caucasian-Americans with multiple sclerosis: a longitudinal study.
    Brain. 2018 Oct 11. pii: 5127751. doi: 10.1093.
    PubMed     Abstract available


  51. DOETS AY, Verboon C, van den Berg B, Harbo T, et al
    Regional variation of Guillain-Barre syndrome.
    Brain. 2018;141:2866-2877.
    PubMed     Abstract available


    September 2018
  52. BAKER D, Pryce G, Amor S, Giovannoni G, et al
    Learning from other autoimmunities to understand targeting of B cells to control multiple sclerosis.
    Brain. 2018 Sep 12. pii: 5095715. doi: 10.1093.
    PubMed     Abstract available


  53. EIJLERS AJC, van Geest Q, Dekker I, Steenwijk MD, et al
    Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study.
    Brain. 2018;141:2605-2618.
    PubMed     Abstract available


    June 2018
  54. MACHADO-SANTOS J, Saji E, Troscher AR, Paunovic M, et al
    The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells.
    Brain. 2018 Jun 4. pii: 5032773. doi: 10.1093.
    PubMed     Abstract available


  55. STANKOFF B, Louapre C
    Can we use regional grey matter atrophy sequence to stage neurodegeneration in multiple sclerosis?
    Brain. 2018;141:1580-1583.
    PubMed    


    May 2018
  56. CAMARA-LEMARROY CR, Metz L, Meddings JB, Sharkey KA, et al
    The intestinal barrier in multiple sclerosis: implications for pathophysiology and therapeutics.
    Brain. 2018 May 30. pii: 5025744. doi: 10.1093.
    PubMed     Abstract available


  57. BARRO C, Benkert P, Disanto G, Tsagkas C, et al
    Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis.
    Brain. 2018 May 30. pii: 5025690. doi: 10.1093.
    PubMed     Abstract available


  58. ESHAGHI A, Marinescu RV, Young AL, Firth NC, et al
    Progression of regional grey matter atrophy in multiple sclerosis.
    Brain. 2018 May 8. pii: 4993898. doi: 10.1093.
    PubMed     Abstract available


  59. LADISLAU L, Suarez-Calvet X, Toquet S, Landon-Cardinal O, et al
    JAK inhibitor improves type I interferon induced damage: proof of concept in dermatomyositis.
    Brain. 2018 May 8. pii: 4993951. doi: 10.1093.
    PubMed     Abstract available


    April 2018
  60. CONRAD BN, Barry RL, Rogers BP, Maki S, et al
    Multiple sclerosis lesions affect intrinsic functional connectivity of the spinal cord.
    Brain. 2018 Apr 10. pii: 4965865. doi: 10.1093.
    PubMed     Abstract available


  61. VAN LANGELAAR J, van der Vuurst de Vries RM, Janssen M, Wierenga-Wolf AF, et al
    T helper 17.1 cells associate with multiple sclerosis disease activity: perspectives for early intervention.
    Brain. 2018 Apr 5. pii: 4961484. doi: 10.1093.
    PubMed     Abstract available


    March 2018
  62. STEYERBERG EW, Claggett B
    Towards personalized therapy for multiple sclerosis: limitations of observational data.
    Brain. 2018 Mar 3. pii: 4919652. doi: 10.1093.
    PubMed    


  63. KALINCIK T
    Reply: Towards personalized therapy for multiple sclerosis: limitations of observational data.
    Brain. 2018 Mar 3. pii: 4919653. doi: 10.1093.
    PubMed    


  64. STEPHENSON EL, Mishra MK, Moussienko D, Laflamme N, et al
    Chondroitin sulfate proteoglycans as novel drivers of leucocyte infiltration in multiple sclerosis.
    Brain. 2018 Mar 1. pii: 4915907. doi: 10.1093.
    PubMed     Abstract available


    February 2018
  65. ARRAMBIDE G, Tintore M, Espejo C, Auger C, et al
    The value of oligoclonal bands in the multiple sclerosis diagnostic criteria.
    Brain. 2018 Feb 16. pii: 4866204. doi: 10.1093.
    PubMed     Abstract available


    January 2018
  66. SMETS I, Fiddes B, Garcia-Perez JE, He D, et al
    Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells.
    Brain. 2018 Jan 18. pii: 4817414. doi: 10.1093.
    PubMed     Abstract available


    December 2017
  67. KIM RY, Mangu D, Hoffman AS, Kovash R, et al
    Oestrogen receptor beta ligand acts on CD11c+ cells to mediate protection in experimental autoimmune encephalomyelitis.
    Brain. 2017 Dec 8. pii: 4710057. doi: 10.1093.
    PubMed     Abstract available


    October 2017
  68. GRANBERG T, Fan Q, Treaba CA, Ouellette R, et al
    In vivo characterization of cortical and white matter neuroaxonal pathology in early multiple sclerosis.
    Brain. 2017 Oct 10. doi: 10.1093.
    PubMed     Abstract available


    September 2017
  69. ROCCA MA, Sormani MP, Rovaris M, Caputo D, et al
    Long-term disability progression in primary progressive multiple sclerosis: a 15-year study.
    Brain. 2017 Sep 27. doi: 10.1093.
    PubMed     Abstract available


  70. DATTA G, Colasanti A, Rabiner EA, Gunn RN, et al
    Neuroinflammation and its relationship to changes in brain volume and white matter lesions in multiple sclerosis.
    Brain. 2017 Sep 23. doi: 10.1093.
    PubMed     Abstract available


  71. KALINCIK T, Manouchehrinia A, Sobisek L, Jokubaitis V, et al
    Towards personalized therapy for multiple sclerosis: prediction of individual treatment response.
    Brain. 2017;140:2426-2443.
    PubMed     Abstract available


    July 2017
  72. SCOLDING NJ, Pasquini M, Reingold SC, Cohen JA, et al
    Cell-based therapeutic strategies for multiple sclerosis.
    Brain. 2017 Jul 21. doi: 10.1093.
    PubMed     Abstract available


    May 2017
  73. DELMONT E, Manso C, Querol L, Cortese A, et al
    Autoantibodies to nodal isoforms of neurofascin in chronic inflammatory demyelinating polyneuropathy.
    Brain. 2017 May 28. doi: 10.1093.
    PubMed     Abstract available


  74. ZRZAVY T, Hametner S, Wimmer I, Butovsky O, et al
    Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.
    Brain. 2017 May 24. doi: 10.1093.
    PubMed     Abstract available


  75. HACOHEN Y, Ciccarelli O, Hemingway C
    Abnormal white matter development in children with multiple sclerosis and monophasic acquired demyelination.
    Brain. 2017;140:1172-1174.
    PubMed    


    April 2017
  76. EL BEHI M, Sanson C, Bachelin C, Guillot-Noel L, et al
    Adaptive human immunity drives remyelination in a mouse model of demyelination.
    Brain. 2017;140:967-980.
    PubMed     Abstract available


    March 2017
  77. LONGONI G, Brown RA, MomayyezSiahkal P, Elliott C, et al
    White matter changes in paediatric multiple sclerosis and monophasic demyelinating disorders.
    Brain. 2017 Mar 14. doi: 10.1093.
    PubMed     Abstract available


  78. JURYNCZYK M, Geraldes R, Probert F, Woodhall MR, et al
    Distinct brain imaging characteristics of autoantibody-mediated CNS conditions and multiple sclerosis.
    Brain. 2017;140:617-627.
    PubMed     Abstract available


    February 2017
  79. PONATH G, Ramanan S, Mubarak M, Housley W, et al
    Myelin phagocytosis by astrocytes after myelin damage promotes lesion pathology.
    Brain. 2017;140.
    PubMed     Abstract available


    June 2016
  80. ARAUJO AQ, Silva MT, Araujo AP
    Zika virus-associated neurological disorders: a review.
    Brain. 2016.
    PubMed     Abstract available


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