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Articles published in Diabetes

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Single Articles


    September 2021
  1. OH E, McCown EM, Ahn M, Garcia PA, et al
    Syntaxin 4 enrichment in beta-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice.
    Diabetes. 2021 Sep 23. pii: db21-0170. doi: 10.2337/db21-0170.
    PubMed     Abstract available


  2. SRIVASTAVA N, Hu H, Vomund AN, Peterson OJ, et al
    Chromogranin A Deficiency Confers Protection from Autoimmune Diabetes Via Multiple Mechanisms.
    Diabetes. 2021 Sep 8. pii: db21-0513. doi: 10.2337/db21-0513.
    PubMed     Abstract available


    August 2021
  3. PAGNI PP, Chaplin J, Wijaranakula M, Wesley JD, et al
    Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes.
    Diabetes. 2021 Aug 13. pii: db21-0327. doi: 10.2337/db21-0327.
    PubMed     Abstract available


    June 2021
  4. LERNMARK A
    Etiology of Autoimmune Islet Disease: Timing Is Everything.
    Diabetes. 2021 Jun 21. pii: dbi18-0034. doi: 10.2337/dbi18-0034.
    PubMed     Abstract available


    May 2021
  5. GALINDO-ALBARRAN A, Castan S, Santamaria JC, Joffre OP, et al
    The repertoire of newly developing regulatory T cells in the type I diabetes-prone NOD mouse is very diverse.
    Diabetes. 2021 May 25. pii: db20-1072. doi: 10.2337/db20-1072.
    PubMed     Abstract available


  6. HILLER H, Beachy DE, Lebowitz JJ, Engler S, et al
    Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes.
    Diabetes. 2021 May 25. pii: db21-0070. doi: 10.2337/db21-0070.
    PubMed     Abstract available


  7. JAHOOR F, Hsu JW, Mehta PB, Keene KR, et al
    Metabolomic profiling of patients with A-beta+ Ketosis-Prone Diabetes during diabetic ketoacidosis.
    Diabetes. 2021 May 21. pii: db21-0066. doi: 10.2337/db21-0066.
    PubMed     Abstract available


  8. MALLONE R, You S
    The SAgA of Antigen-Specific Immunotherapy for Type 1 Diabetes.
    Diabetes. 2021 May 20. pii: dbi21-0011. doi: 10.2337/dbi21-0011.
    PubMed    


  9. BETTINI M, Bettini ML
    Function, Failure, and the Future Potential of Tregs in Type 1 Diabetes.
    Diabetes. 2021 May 20. pii: dbi18-0058. doi: 10.2337/dbi18-0058.
    PubMed     Abstract available


  10. BRITTEN-JONES AC, Kamel JT, Roberts LJ, Braat S, et al
    Investigating the neuroPRotective effect of Oral Omega-3 Fatty acid Supplementation in type 1 diabetes (nPROOFS1): a randomised, placebo-controlled trial.
    Diabetes. 2021 May 5. pii: db21-0136. doi: 10.2337/db21-0136.
    PubMed     Abstract available


  11. RODRIGUEZ-CALVO T, Chen YC, Verchere CB, Haataja L, et al
    Altered beta-Cell Prohormone Processing and Secretion in Type 1 Diabetes.
    Diabetes. 2021 May 4. pii: dbi20-0034. doi: 10.2337/dbi20-0034.
    PubMed     Abstract available


  12. GREENBAUM CJ
    A Key to T1D Prevention: Screening and Monitoring Relatives as Part of Clinical Care.
    Diabetes. 2021;70:1029-1037.
    PubMed     Abstract available


    April 2021
  13. CARRY P, Vanderlinden LA, Johnson RK, Buckner T, et al
    Phospholipid Levels at Seroconversion are Associated with Resolution of Persistent Islet Autoimmunity: The Diabetes Autoimmunity Study in the Young.
    Diabetes. 2021 Apr 16. pii: db20-1251. doi: 10.2337/db20-1251.
    PubMed     Abstract available


  14. LINSLEY PS, Greenbaum CJ, Nepom GT
    Uncovering Pathways to Personalized Therapies in Type 1 Diabetes.
    Diabetes. 2021;70:831-841.
    PubMed     Abstract available


    March 2021
  15. FORBES JM, McCarthy DA, Kassianos AJ, Baskerville T, et al
    T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early Diabetes.
    Diabetes. 2021 Mar 18. pii: db20-1081. doi: 10.2337/db20-1081.
    PubMed     Abstract available


  16. BAGGER JI, Grondahl M, Lund A, Holst JJ, et al
    Glucagonostatic Potency of GLP-1 in Patients with Type 2 Diabetes, in Patients with Type 1 Diabetes and in Healthy Controls.
    Diabetes. 2021 Mar 15. pii: db20-0998. doi: 10.2337/db20-0998.
    PubMed     Abstract available


    February 2021
  17. HALLER MJ, Jacobsen LM, Posgai AL, Schatz DA, et al
    How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
    Diabetes. 2021 Feb 25. pii: dbi20-0045. doi: 10.2337/dbi20-0045.
    PubMed     Abstract available


  18. LIN A, Mack JA, Bruggeman B, Jacobsen LM, et al
    Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report.
    Diabetes. 2021 Feb 25. pii: db20-1103. doi: 10.2337/db20-1103.
    PubMed     Abstract available


  19. HERDER C, Maalmi H, Strassburger K, Zaharia OP, et al
    Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset Diabetes.
    Diabetes. 2021 Feb 19. pii: db20-1054. doi: 10.2337/db20-1054.
    PubMed     Abstract available


  20. BOLDISON J, Thayer TC, Davies J, Wong FS, et al
    Natural Protection From Type 1 Diabetes in Non Obese Diabetic (Nod) Mice is Characterised by a Unique Pancreatic Islet Phenotype.
    Diabetes. 2021 Feb 2. pii: db20-0945. doi: 10.2337/db20-0945.
    PubMed     Abstract available


  21. GLIEBERMAN AL, Pope BD, Melton DA, Parker KK, et al
    Building Biomimetic Potency Tests for Islet Transplantation.
    Diabetes. 2021;70:347-363.
    PubMed     Abstract available


  22. PETRELLI A, Atkinson MA, Pietropaolo M, Giannoukakis N, et al
    Modulation of Leukocytes of the Innate Arm of the Immune System as a Potential Approach to Prevent the Onset and Progression of Type 1 Diabetes.
    Diabetes. 2021;70:313-322.
    PubMed     Abstract available


    January 2021
  23. ESPES D, Carlsson PO, Selvaraju RK, Rosestedt M, et al
    Longitudinal Assessment of (11)C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes.
    Diabetes. 2021 Jan 21. pii: db20-0776. doi: 10.2337/db20-0776.
    PubMed     Abstract available


  24. MHANNA V, Fourcade G, Barennes P, Quiniou V, et al
    Impaired Activated/Memory Regulatory T Cell Clonal Expansion Instigates Diabetes in NOD Mice.
    Diabetes. 2021 Jan 21. pii: db20-0896. doi: 10.2337/db20-0896.
    PubMed     Abstract available


  25. FIRDESSA-FITE R, Johnson SN, Leon MA, Khosravi-Maharlooei M, et al
    Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes.
    Diabetes. 2021 Jan 19. pii: db20-0845. doi: 10.2337/db20-0845.
    PubMed     Abstract available


  26. ROSS JJ, Wasserfall CH, Bacher R, Perry DJ, et al
    Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size.
    Diabetes. 2021 Jan 13. pii: db20-0995. doi: 10.2337/db20-0995.
    PubMed     Abstract available


  27. WILLIAMS MD, Bacher R, Perry DJ, Grace CR, et al
    Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis.
    Diabetes. 2021 Jan 8. pii: db20-0937. doi: 10.2337/db20-0937.
    PubMed     Abstract available


  28. HAUKKA J, Sandholm N, Valo E, Forsblom C, et al
    Novel Linkage Peaks Discovered for Diabetic Nephropathy in Individuals With Type 1 Diabetes.
    Diabetes. 2021 Jan 7. pii: db20-0158. doi: 10.2337/db20-0158.
    PubMed     Abstract available


  29. RODRIGUEZ-CALVO T, Krogvold L, Amirian N, Dahl-Jorgensen K, et al
    One in Ten CD8+ Cells in the Pancreas of Living Individuals With Recent Onset Type 1 Diabetes Recognizes the Preproinsulin Epitope PPI15-24.
    Diabetes. 2021 Jan 7. pii: db20-0908. doi: 10.2337/db20-0908.
    PubMed     Abstract available


    December 2020
  30. SNOWHITE I, Pastori R, Sosenko J, Cayetano SM, et al
    Baseline Assessment of Circulating microRNAs Near Diagnosis of Type 1 Diabetes Predicts Future Stimulated Insulin Secretion.
    Diabetes. 2020 Dec 4. pii: db20-0817. doi: 10.2337/db20-0817.
    PubMed     Abstract available


  31. BARRETT HL, Donaghue KC, Forbes JM
    Going in Early: Hypoxia as a Target for Kidney Disease Prevention in Diabetes?
    Diabetes. 2020;69:2578-2580.
    PubMed    


  32. AZOURY ME, Tarayrah M, Afonso G, Pais A, et al
    Peptides Derived From Insulin Granule Proteins Are Targeted by CD8(+) T Cells Across MHC Class I Restrictions in Humans and NOD Mice.
    Diabetes. 2020;69:2678-2690.
    PubMed     Abstract available


    November 2020
  33. SODRE FMC, Bissenova S, Bruggeman Y, Tilvawala R, et al
    Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice.
    Diabetes. 2020 Nov 17. pii: db20-0421. doi: 10.2337/db20-0421.
    PubMed     Abstract available


  34. FLOYEL T, Meyerovich K, Prause MC, Kaur S, et al
    SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates beta-Cell Apoptosis and Glycaemic Control in Newly Diagnosed Patients.
    Diabetes. 2020 Nov 17. pii: db20-0092. doi: 10.2337/db20-0092.
    PubMed     Abstract available


  35. SHA S, Pearson JA, Peng J, Hu Y, et al
    TLR9-Deficiency in B Cells Promotes Immune Tolerance via IL-10 in a Type 1 Diabetes Mouse Model.
    Diabetes. 2020 Nov 5. pii: db20-0373. doi: 10.2337/db20-0373.
    PubMed     Abstract available


  36. ADVANI A
    Acute Kidney Injury: A Bona Fide Complication of Diabetes.
    Diabetes. 2020;69:2229-2237.
    PubMed     Abstract available


    October 2020
  37. RUSSO F, Citro A, Squeri G, Sanvito F, et al
    InsB9-23 Gene Transfer To Hepatocytes-Based Combined Therapy Abrogates Recurrence of Type-1 Diabetes After Islet Transplantation.
    Diabetes. 2020 Oct 29. pii: db19-1249. doi: 10.2337/db19-1249.
    PubMed     Abstract available


  38. THAYER TC, Davies J, Pearson JA, Hanna SJ, et al
    Differentiating MHC-Dependent and -Independent Mechanisms of Lymph Node Stromal Cell Regulation of Proinsulin-Specific CD8(+) T-Cells in type 1 Diabetes.
    Diabetes. 2020 Oct 29. pii: db19-1050. doi: 10.2337/db19-1050.
    PubMed     Abstract available


  39. LI Q, Liu X, Yang J, Erlund I, et al
    Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: the TEDDY Study.
    Diabetes. 2020 Oct 26. pii: db20-0696. doi: 10.2337/db20-0696.
    PubMed     Abstract available


    September 2020
  40. THIEM K, van Dierendonck XAMH, Janssen AWM, Boogaard JP, et al
    A High Glycemic Burden Relates to Functional and Metabolic Alterations of Human Monocytes in Patients with Type 1 Diabetes.
    Diabetes. 2020 Sep 25. pii: db20-0568. doi: 10.2337/db20-0568.
    PubMed     Abstract available


    August 2020
  41. ZHAO LP, Papadopoulos GK, Kwok WW, Moustakas AK, et al
    Next Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes.
    Diabetes. 2020 Aug 31. pii: db20-0374. doi: 10.2337/db20-0374.
    PubMed     Abstract available


  42. BUZZETTI R, Tuomi T, Mauricio D, Pietropaolo M, et al
    Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel.
    Diabetes. 2020 Aug 26. pii: dbi20-0017. doi: 10.2337/dbi20-0017.
    PubMed     Abstract available


  43. AHLQVIST E, Prasad RB, Groop L
    Subtypes of Type 2 Diabetes Determined From Clinical Parameters.
    Diabetes. 2020 Aug 25. pii: dbi20-0001. doi: 10.2337/dbi20-0001.
    PubMed     Abstract available


  44. FILIP P, Canna A, Moheet A, Bednarik P, et al
    Structural Alterations in Deep Brain Structures in Type 1 Diabetes.
    Diabetes. 2020 Aug 24. pii: db19-1100. doi: 10.2337/db19-1100.
    PubMed     Abstract available


  45. JAFFA MA, Bebu I, Luttrell D, Braffett BH, et al
    Longitudinal Plasma Kallikrein Levels and Their Association with the Risk of Cardiovascular Disease Outcomes in Type 1 Diabetes in DCCT/EDIC.
    Diabetes. 2020 Aug 21. pii: db20-0427. doi: 10.2337/db20-0427.
    PubMed     Abstract available


  46. BONE RN, Oyebamiji O, Talware S, Selvaraj S, et al
    A Computational Approach for Defining a Signature of beta-Cell Golgi Stress in Diabetes Mellitus.
    Diabetes. 2020 Aug 20. pii: db20-0636. doi: 10.2337/db20-0636.
    PubMed     Abstract available


    July 2020
  47. CUROVIC VR, Suvitaival T, Mattila I, Ahonen L, et al
    Circulating Metabolites and Lipids are Associated to Diabetic Retinopathy in Individuals With Type 1 Diabetes.
    Diabetes. 2020 Jul 31. pii: db20-0104. doi: 10.2337/db20-0104.
    PubMed     Abstract available


  48. VINOVSKIS C, Li LP, Prasad P, Tommerdahl K, et al
    Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes.
    Diabetes. 2020 Jul 31. pii: db20-0457. doi: 10.2337/db20-0457.
    PubMed     Abstract available


  49. KRAMER F, Martinson AM, Papayannopoulou T, Kanter JE, et al
    Myocardial Infarction Does not Accelerate Atherosclerosis in a Mouse Model of Type 1 Diabetes.
    Diabetes. 2020 Jul 21. pii: db20-0152. doi: 10.2337/db20-0152.
    PubMed     Abstract available


  50. JAMES EA, Mallone R, Kent SC, DiLorenzo TP, et al
    T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal.
    Diabetes. 2020;69:1311-1335.
    PubMed     Abstract available


  51. ARRIBAS-LAYTON D, Guyer P, Delong T, Dang M, et al
    Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01.
    Diabetes. 2020;69:1492-1502.
    PubMed     Abstract available


    June 2020
  52. BARRA JM, Kozlovskaya V, Kharlampieva E, Tse HM, et al
    Localized Immunosuppression with Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection.
    Diabetes. 2020 Jun 25. pii: db20-0248. doi: 10.2337/db20-0248.
    PubMed     Abstract available


    May 2020
  53. FOLAND-ROSS LC, Tong G, Mauras N, Cato A, et al
    Brain Function Differences in Children With Type 1 Diabetes: An fMRI Study of Working Memory.
    Diabetes. 2020 May 29. pii: db20-0123. doi: 10.2337/db20-0123.
    PubMed     Abstract available


  54. SIMMONS KM, Mitchell AM, Alkanani AA, McDaniel KA, et al
    Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02.
    Diabetes. 2020 May 21. pii: db20-0038. doi: 10.2337/db20-0038.
    PubMed     Abstract available


  55. SOSENKO JM, Skyler JS, Herold KC, Schatz DA, et al
    Slowed Metabolic Decline after One Year of Oral Insulin Treatment among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 and TrialNet Oral Insulin Prevention Trials.
    Diabetes. 2020 May 21. pii: db20-0166. doi: 10.2337/db20-0166.
    PubMed     Abstract available


  56. LU G, Rausell-Palamos F, Zhang J, Zheng Z, et al
    Dextran Sulfate Protects Pancreatic beta-Cells, Reduces Autoimmunity and Ameliorates Type 1 Diabetes.
    Diabetes. 2020 May 7. pii: db19-0725. doi: 10.2337/db19-0725.
    PubMed     Abstract available


  57. GREGORY JM, Cherrington AD, Moore DJ
    The Peripheral Peril: Injected Insulin Induces Insulin Insensitivity in Type 1 Diabetes.
    Diabetes. 2020;69:837-847.
    PubMed     Abstract available


    April 2020
  58. BOLO NR, Jacobson AM, Musen G, Keshavan MS, et al
    Acute Hyperglycemia Increases Brain Pregenual Anterior Cingulate Cortex Glutamate Concentrations in Type 1 Diabetes Mellitus.
    Diabetes. 2020 Apr 15. pii: db19-0936. doi: 10.2337/db19-0936.
    PubMed     Abstract available


  59. ZHAO LP, Papadopoulos GK, Kwok WW, Moustakas AK, et al
    Motifs of Three HLA-DQ Amino Acid Residues (alpha44, beta57, beta135) Capture Full Association with the Risk of Type 1 Diabetes in DQ2 and DQ8 Children.
    Diabetes. 2020 Apr 3. pii: db20-0075. doi: 10.2337/db20-0075.
    PubMed     Abstract available


    March 2020
  60. CARI L, Montanucci P, Basta G, Petrillo MG, et al
    Microencapsulated G3C hybridoma cell graft delays the onset of spontaneous diabetes in NOD mice by an expansion of Gitr(+) Treg cells.
    Diabetes. 2020 Mar 13. pii: db19-0087. doi: 10.2337/db19-0087.
    PubMed     Abstract available


  61. MILLER RG, Orchard TJ
    Understanding Metabolic Memory: A Tale of Two Studies.
    Diabetes. 2020;69:291-299.
    PubMed     Abstract available


  62. BETTINI M, Scavuzzo MA, Liu B, Kolawole E, et al
    A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells.
    Diabetes. 2020;69:392-400.
    PubMed     Abstract available


    February 2020
  63. KUCK JL, Bonhof GJ, Strom A, Zaharia OP, et al
    Impairment in Baroreflex Sensitivity in Recent-Onset Type 2 Diabetes Without Progression Over 5 Years.
    Diabetes. 2020 Feb 21. pii: db19-0990. doi: 10.2337/db19-0990.
    PubMed     Abstract available


  64. STANKUTE I, Verkauskiene R, Blouin JL, Klee P, et al
    Systematic Genetic Study of Diabetic Youth in a Single Country Reveals the Prevalence of Diabetes Subtypes, Novel Candidate Genes, and Response to Precision Therapy.
    Diabetes. 2020 Feb 21. pii: db19-0974. doi: 10.2337/db19-0974.
    PubMed     Abstract available


  65. BRAFFETT BH, Gubitosi-Klug RA, Albers JW, Feldman EL, et al
    Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study.
    Diabetes. 2020 Feb 12. pii: db19-1046. doi: 10.2337/db19-1046.
    PubMed     Abstract available


  66. LI Q, Parikh H, Butterworth MD, Lernmark A, et al
    Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study.
    Diabetes. 2020 Feb 6. pii: db19-0756. doi: 10.2337/db19-0756.
    PubMed     Abstract available


    January 2020
  67. FORGETTA V, Manousaki D, Istomine R, Ross S, et al
    Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes.
    Diabetes. 2020 Jan 31. pii: db19-0831. doi: 10.2337/db19-0831.
    PubMed     Abstract available


  68. MOCHIDA T, Ueno H, Yamazoe N, Hiyoshi H, et al
    Insulin-Deficient Diabetic Condition Upregulates Insulin Secreting Capacity of Human iPSC-Derived Pancreatic Endocrine Progenitor Cells After Implantation in Mice.
    Diabetes. 2020 Jan 31. pii: db19-0728. doi: 10.2337/db19-0728.
    PubMed     Abstract available


  69. JORNS A J A, Wedekind D W D, Jahne J J J, Lenzen S L S, et al
    Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared to Type 1 Diabetes Mellitus.
    Diabetes. 2020 Jan 23. pii: db19-0865. doi: 10.2337/db19-0865.
    PubMed     Abstract available


  70. KNOOP J, Eugster A, Gavrisan A, Lickert R, et al
    Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4(+) T Cells in Offspring.
    Diabetes. 2020 Jan 2. pii: db19-0751. doi: 10.2337/db19-0751.
    PubMed     Abstract available


    December 2019
  71. EID SA, El Massry M, Hichor M, Haddad M, et al
    Targeting the NADPH Oxidase-4 and Liver X Receptor Signaling Axis Preserve Schwann Cell Integrity in Diabetic Mice.
    Diabetes. 2019 Dec 27. pii: db19-0517. doi: 10.2337/db19-0517.
    PubMed     Abstract available


  72. SHAPIRO MR, Wasserfall CH, McGrail SM, Posgai AL, et al
    Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.
    Diabetes. 2019 Dec 11. pii: db19-0942. doi: 10.2337/db19-0942.
    PubMed     Abstract available


  73. LIU B, Hood JD, Kolawole EM, Woodruff DM, et al
    A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery.
    Diabetes. 2019 Dec 5. pii: db19-0399. doi: 10.2337/db19-0399.
    PubMed     Abstract available


    November 2019
  74. FROHNERT BI, Webb-Robertson BJ, Bramer LM, Reehl SM, et al
    Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources.
    Diabetes. 2019 Nov 18. pii: db18-1263. doi: 10.2337/db18-1263.
    PubMed     Abstract available


  75. CABELLO-KINDELAN C, Mackey S, Sands A, Rodriguez J, et al
    Immunomodulation Followed By Antigen-Specific Treg Infusion Controls Islet Autoimmunity.
    Diabetes. 2019 Nov 11. pii: db19-0061. doi: 10.2337/db19-0061.
    PubMed     Abstract available


    October 2019
  76. LI M, Wang S, Xu K, Chen Y, et al
    High prevalence of a monogenic cause in Han Chinese diagnosed with type 1 diabetes, partly driven by non-syndromic recessive WFS1 mutations.
    Diabetes. 2019 Oct 28. pii: db19-0510. doi: 10.2337/db19-0510.
    PubMed     Abstract available


  77. KUSMARTSEVA I, Beery M, Hiller H, Padilla M, et al
    Temporal Analysis of Amylase Expression in Control, Autoantibody Positive, and Type 1 Diabetes Pancreatic Tissues.
    Diabetes. 2019 Oct 9. pii: db19-0554. doi: 10.2337/db19-0554.
    PubMed     Abstract available


  78. KOSKINEN MK, Mikk ML, Laine AP, Lempainen J, et al
    Longitudinal Pattern of First-Phase Insulin Response Is Associated with Genetic Variants Outside the Class II HLA Region in Children with Multiple Autoantibodies.
    Diabetes. 2019 Oct 7. pii: db19-0329. doi: 10.2337/db19-0329.
    PubMed     Abstract available


  79. SHARMA S, Pettus J, Gottschalk M, Abe B, et al
    Single-Cell Analysis of CD4 T Cells in Type 1 Diabetes: From Mouse to Man, How to Perform Mechanistic Studies.
    Diabetes. 2019;68:1886-1891.
    PubMed     Abstract available


    September 2019
  80. FLORIJN BW, Duijs JMGJ, Levels JH, Dallinga-Thie GM, et al
    Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic miRNAs Between Extracellular Vesicles, HDL and Ago-2.
    Diabetes. 2019 Sep 10. pii: db18-1360. doi: 10.2337/db18-1360.
    PubMed     Abstract available


    August 2019
  81. VUORI N, Sandholm N, Kumar A, Hietala K, et al
    CACNB2 is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes.
    Diabetes. 2019 Aug 22. pii: db19-0130. doi: 10.2337/db19-0130.
    PubMed     Abstract available


  82. BADILLO FG, Tegou FZ, Abreu MM, Masina R, et al
    CCL21 Expression in beta-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice.
    Diabetes. 2019 Aug 1. pii: db19-0239. doi: 10.2337/db19-0239.
    PubMed     Abstract available


  83. UNANUE ER, Wan X
    The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity.
    Diabetes. 2019;68:1544-1551.
    PubMed     Abstract available



  84. In This Issue of Diabetes.
    Diabetes. 2019;68:1539-1540.
    PubMed    


    July 2019
  85. MATHEW AV, Jaiswal M, Ang L, Michailidis G, et al
    Impaired Amino Acid and TCA Metabolism and Cardiovascular Autonomic Neuropathy Progression in Type 1 Diabetes.
    Diabetes. 2019 Jul 23. pii: db19-0145. doi: 10.2337/db19-0145.
    PubMed     Abstract available


  86. KALLIONPAA H, Somani J, Tuomela S, Ullah U, et al
    Early Detection of Peripheral Blood Cell Signature in Children Developing Beta-Cell Autoimmunity at a Young Age.
    Diabetes. 2019 Jul 16. pii: db19-0287. doi: 10.2337/db19-0287.
    PubMed     Abstract available


  87. SOFI MH, Johnson BM, Gudi RR, Jolly A, et al
    Polysaccharide A-Dependent Opposing Effects of Mucosal and Systemic Exposures to Human Gut Commensal Bacteroides Fragilis in Type 1 Diabetes.
    Diabetes. 2019 Jul 16. pii: db19-0211. doi: 10.2337/db19-0211.
    PubMed     Abstract available


  88. AHMED S, Cerosaletti K, James E, Long SA, et al
    Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
    Diabetes. 2019;68:1366-1379.
    PubMed     Abstract available


    June 2019
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  92. In This Issue of Diabetes.
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    PubMed    


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    Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes.
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  96. PURCELL AW, Sechi S, DiLorenzo TP
    The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes.
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    April 2019
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    Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data.
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    Trisomy 21 is a Cause of Permanent Neonatal Diabetes that is Autoimmune but not HLA Associated.
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    Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes.
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    T Cell-Specific PTPN2-Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Co-Morbidities.
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    Cardiac Autonomic Function is Associated With Myocardial Flow Reserve in Type 1 Diabetes.
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    HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of islet beta-Cells from Donors with Type 1 Diabetes.
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  103. THORENS B
    Targeting the Brain to Cure Type 2 Diabetes.
    Diabetes. 2019;68:476-478.
    PubMed    



  104. In This Issue of Diabetes.
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    PubMed    


    February 2019
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    Glucose Metabolism is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes Mellitus.
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    Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families.
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    Epitope Stealing as Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.
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  111. In This Issue of Diabetes.
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    Adaptive beta-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance.
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    Low Level Insulin Content Within Abundant Non-Beta Islet Endocrine Cells in Long-Standing Type 1 Diabetes.
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    November 2018
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    NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.
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  117. MILLER RG, Costacou T, Orchard TJ
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    VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy.
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  121. In This Issue of Diabetes.
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    October 2018
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    Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children.
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    September 2018
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  124. DRUCKER DJ
    The Ascending GLP-1 Road From Clinical Safety to Reduction of Cardiovascular Complications.
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  125. ACCILI D
    Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture.
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  126. BAKER RL, Jamison BL, Wiles TA, Lindsay RS, et al
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    August 2018
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    July 2018
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    Validation of (111)In-Exendin SPECT for the Determination of the Beta Cell Mass in BioBreeding Diabetes Prone Rats.
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    June 2018
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  139. JAMES EA, Pietropaolo M, Mamula MJ
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  140. In This Issue of Diabetes.
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    Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway.
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    May 2018
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    Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
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    Metabolic Karma-The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture.
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  144. In This Issue of Diabetes.
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    April 2018
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    Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.
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    Inhibition of Soluble Epoxide Hydrolase 2 Ameliorates Diabetic Keratopathy and Impaired Wound Healing in Mouse Corneas.
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    March 2018
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    Altered Brain Dynamics in Patients with Type 1 Diabetes During Working Memory Processing.
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    February 2018
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    Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice.
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    Improved Murine-MHC-Deficient HLA-Transgenic NOD-Mouse Models for Type 1 Diabetes Therapy Development.
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    Circulating miRNA Profiles Associated With Hyperglycemia in Patients With Type 1 Diabetes Mellitus.
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    January 2018
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    Loss of B Cell Anergy in Type 1 Diabetes is Associated with High Risk HLA and non-HLA Disease Susceptibility Alleles.
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    Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes.
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  157. LI J, Huynh P, Dai A, Wu T, et al
    Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
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  158. JOHNSON MB, De Franco E, Allen HL, Al Senani A, et al
    Erratum. Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes. Diabetes 2017;66:2316-2322.
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    Potein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes.
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    December 2017
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    Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No.
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    November 2017
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    Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents.
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    October 2017
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    Thioredoxin-1 Overexpression in the Ventromedial Nucleus of the Hypothalamus (VMH) Preserves the Counterregulatory Response to Hypoglycemia During Type 1 Diabetes Mellitus in Male Rats.
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  163. GU J, Yan X, Dai X, Wang Y, et al
    Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts.
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  164. MILLER WP, Yang C, Mihailescu ML, Moore JA, et al
    Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes.
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    September 2017
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    Effect of Exercise-Induced Lactate Elevation on Brain Lactate Levels During Hypoglycemia in Patients with Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
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    Beta Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.
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    The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report.
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    Response to Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of beta-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345.
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  183. HERNANDEZ R, Graves SA, Gregg T, VanDeusen HR, et al
    Radiomanganese PET Detects Changes in Functional beta-cell Mass in Mouse Models of Diabetes.
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  184. JOHNSON MB, De Franco E, Lango-Allen H, Al Senani A, et al
    Recessively Inherited Lrba Mutations Cause Autoimmunity Presenting as Neonatal Diabetes.
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  185. TUNCAY E, Bitirim VC, Durak A, Carrat GRJ, et al
    Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart.
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  186. ROJAS-CANALES D, Penko D, Myo Min KK, Parham KA, et al
    Local Sphingosine Kinase 1 Activity Improves Islet Transplantation.
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    April 2017
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    Magnetic Resonance Neurography Visualizes Abnormalities in Sciatic and Tibial Nerves in Patients with Type 1 Diabetes and Neuropathy.
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    A Single Bout of High-Intensity Interval Training Reduces Awareness of Subsequent Hypoglycemia in Patients with Type 1 Diabetes.
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    Renal and Vascular Effects of Uric Acid Lowering in Normouricemic Patients with Uncomplicated Type 1 Diabetes.
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  190. THELIN MA, Kissler S, Vigneault F, Watters AL, et al
    In Vivo Enrichment of Diabetogenic T Cells.
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    Neu5Gc and alpha1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs.
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    Metabolite Profiling of LADA Challenges the View of a Metabolically Distinct Subtype.
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    March 2017
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    The Effect of Diabetes on Cortical Function in Stroke: Implications for Post-Stroke Plasticity.
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    February 2017
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    Co-transplantation of Mesenchymal Stem Cells with Neonatal Porcine Islets Improve Graft Function in Diabetic Mice.
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    Spinal Disinhibition in Experimental and Clinical Painful Diabetic Neuropathy.
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    Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?
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    PubMed    


    January 2017
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    Pro-inflammatory Effects of Hypoglycemia in Humans with or without Diabetes.
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    December 2016
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    Interferon gamma Limits Diabetogenic CD8 T-Cell Effector Responses in Type-1 Diabetes.
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    November 2016
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    Glomerular Endothelial Mitochondrial Dysfunction is Essential and Characteristic of Diabetic Kidney Disease Susceptibility.
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    Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy.
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    Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease.
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    The Insulin-Like Growth Factor Axis: A New Player in Gestational Diabetes Mellitus?
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    PubMed    


    October 2016
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    Compensatory Hyper-Connectivity in Developing Brains of Young Children with Type 1 Diabetes.
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    September 2016
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    Anti-Thymocyte Globulin + G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders with Established Type 1 Diabetes.
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  206. SZASZ T, Wenceslau CF, Burgess B, Nunes KP, et al
    Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type I Diabetes.
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    August 2016
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  208. DREXHAGE HA, Dik WA, Leenen PJ, Versnel MA, et al
    The Immune Pathogenesis of Type 1 Diabetes: Not Only Thinking Outside the Cell but Also Outside the Islet and Out of the Box.
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    PubMed    


  209. NEL I, Lehuen A
    Defective Invariant Natural Killer T-Cell Suppression in Patients With Type 1 Diabetes.
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    PubMed    


  210. BOGDANI M
    Thinking Outside the Cell: A Key Role for Hyaluronan in the Pathogenesis of Human Type 1 Diabetes.
    Diabetes. 2016;65:2105-14.
    PubMed    


    July 2016
  211. MCNEILLY AD, Gallagher JR, Dinkova-Kostova AT, Hayes JD, et al
    Nrf2-mediated neuroprotection against recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes.
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    Skeletal Metabolism, Fracture Risk, and Fracture Outcomes in Type 1 and Type 2 Diabetes.
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    June 2016
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    Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Mellitus is the Result of Altered Notch Signaling.
    Diabetes. 2016 Jun 22. pii: db151577.
    PubMed     Abstract available


  215. BELGARDT BF, Lammert E
    DYRK1A: A Promising Drug Target for Islet Transplant-Based Diabetes Therapies.
    Diabetes. 2016;65:1496-8.
    PubMed    


    May 2016
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    Effect of GABA A receptor activation on counterregulatory responses to subsequent exercise in individuals with type 1 diabetes.
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  217. MUNDINGER TO, Mei Q, Foulis AK, Fligner CL, et al
    Human type 1 diabetes is characterized by an early, marked, sustained and islet-selective loss of sympathetic nerves.
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    Amelioration of Diabetes Mellitus by Protein S.
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    April 2016
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    Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes.
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  220. ROSHANDEL D, Klein R, Klein BE, Wolffenbuttel BH, et al
    A New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes also Associated with Blood and Skin Glycated Proteins.
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  221. TELLECHEA A, Leal EC, Kafanas A, Auster ME, et al
    Mast Cells Regulate Wound Healing in Diabetes.
    Diabetes. 2016 Apr 8. pii: db150340.
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  222. MACDONALD MJ, Hasan NM, Ansari IH, Longacre MJ, et al
    Discovery of a Genetic Metabolic Cause for Mauriac Syndrome in Type 1 Diabetes.
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  223. PATEL KA, Oram RA, Flanagan SE, De Franco E, et al
    Type 1 Diabetes Genetic Risk Score: a novel tool to discriminate monogenic and type 1 diabetes.
    Diabetes. 2016 Apr 5. pii: db151690.
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  224. USERO L, Sanchez A, Pizarro E, Xufre C, et al
    IL-13 pathway alterations impair iNKT cell-mediated regulation of T effector cells in Type 1 Diabetes.
    Diabetes. 2016 Apr 5. pii: db151350.
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    PubMed    


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