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Articles published in Diabetes

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    September 2021
  1. OH E, McCown EM, Ahn M, Garcia PA, et al
    Syntaxin 4 enrichment in beta-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice.
    Diabetes. 2021 Sep 23. pii: db21-0170. doi: 10.2337/db21-0170.
    PubMed     Abstract available

  2. SRIVASTAVA N, Hu H, Vomund AN, Peterson OJ, et al
    Chromogranin A Deficiency Confers Protection from Autoimmune Diabetes Via Multiple Mechanisms.
    Diabetes. 2021 Sep 8. pii: db21-0513. doi: 10.2337/db21-0513.
    PubMed     Abstract available

    August 2021
  3. PAGNI PP, Chaplin J, Wijaranakula M, Wesley JD, et al
    Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes.
    Diabetes. 2021 Aug 13. pii: db21-0327. doi: 10.2337/db21-0327.
    PubMed     Abstract available

    June 2021
    Etiology of Autoimmune Islet Disease: Timing Is Everything.
    Diabetes. 2021 Jun 21. pii: dbi18-0034. doi: 10.2337/dbi18-0034.
    PubMed     Abstract available

    May 2021
  5. GALINDO-ALBARRAN A, Castan S, Santamaria JC, Joffre OP, et al
    The repertoire of newly developing regulatory T cells in the type I diabetes-prone NOD mouse is very diverse.
    Diabetes. 2021 May 25. pii: db20-1072. doi: 10.2337/db20-1072.
    PubMed     Abstract available

  6. HILLER H, Beachy DE, Lebowitz JJ, Engler S, et al
    Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes.
    Diabetes. 2021 May 25. pii: db21-0070. doi: 10.2337/db21-0070.
    PubMed     Abstract available

  7. JAHOOR F, Hsu JW, Mehta PB, Keene KR, et al
    Metabolomic profiling of patients with A-beta+ Ketosis-Prone Diabetes during diabetic ketoacidosis.
    Diabetes. 2021 May 21. pii: db21-0066. doi: 10.2337/db21-0066.
    PubMed     Abstract available

  8. MALLONE R, You S
    The SAgA of Antigen-Specific Immunotherapy for Type 1 Diabetes.
    Diabetes. 2021 May 20. pii: dbi21-0011. doi: 10.2337/dbi21-0011.

  9. BETTINI M, Bettini ML
    Function, Failure, and the Future Potential of Tregs in Type 1 Diabetes.
    Diabetes. 2021 May 20. pii: dbi18-0058. doi: 10.2337/dbi18-0058.
    PubMed     Abstract available

  10. BRITTEN-JONES AC, Kamel JT, Roberts LJ, Braat S, et al
    Investigating the neuroPRotective effect of Oral Omega-3 Fatty acid Supplementation in type 1 diabetes (nPROOFS1): a randomised, placebo-controlled trial.
    Diabetes. 2021 May 5. pii: db21-0136. doi: 10.2337/db21-0136.
    PubMed     Abstract available

  11. RODRIGUEZ-CALVO T, Chen YC, Verchere CB, Haataja L, et al
    Altered beta-Cell Prohormone Processing and Secretion in Type 1 Diabetes.
    Diabetes. 2021 May 4. pii: dbi20-0034. doi: 10.2337/dbi20-0034.
    PubMed     Abstract available

    A Key to T1D Prevention: Screening and Monitoring Relatives as Part of Clinical Care.
    Diabetes. 2021;70:1029-1037.
    PubMed     Abstract available

    April 2021
  13. CARRY P, Vanderlinden LA, Johnson RK, Buckner T, et al
    Phospholipid Levels at Seroconversion are Associated with Resolution of Persistent Islet Autoimmunity: The Diabetes Autoimmunity Study in the Young.
    Diabetes. 2021 Apr 16. pii: db20-1251. doi: 10.2337/db20-1251.
    PubMed     Abstract available

  14. LINSLEY PS, Greenbaum CJ, Nepom GT
    Uncovering Pathways to Personalized Therapies in Type 1 Diabetes.
    Diabetes. 2021;70:831-841.
    PubMed     Abstract available

    March 2021
  15. FORBES JM, McCarthy DA, Kassianos AJ, Baskerville T, et al
    T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early Diabetes.
    Diabetes. 2021 Mar 18. pii: db20-1081. doi: 10.2337/db20-1081.
    PubMed     Abstract available

  16. BAGGER JI, Grondahl M, Lund A, Holst JJ, et al
    Glucagonostatic Potency of GLP-1 in Patients with Type 2 Diabetes, in Patients with Type 1 Diabetes and in Healthy Controls.
    Diabetes. 2021 Mar 15. pii: db20-0998. doi: 10.2337/db20-0998.
    PubMed     Abstract available

    February 2021
  17. HALLER MJ, Jacobsen LM, Posgai AL, Schatz DA, et al
    How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
    Diabetes. 2021 Feb 25. pii: dbi20-0045. doi: 10.2337/dbi20-0045.
    PubMed     Abstract available

  18. LIN A, Mack JA, Bruggeman B, Jacobsen LM, et al
    Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report.
    Diabetes. 2021 Feb 25. pii: db20-1103. doi: 10.2337/db20-1103.
    PubMed     Abstract available

  19. HERDER C, Maalmi H, Strassburger K, Zaharia OP, et al
    Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset Diabetes.
    Diabetes. 2021 Feb 19. pii: db20-1054. doi: 10.2337/db20-1054.
    PubMed     Abstract available

  20. BOLDISON J, Thayer TC, Davies J, Wong FS, et al
    Natural Protection From Type 1 Diabetes in Non Obese Diabetic (Nod) Mice is Characterised by a Unique Pancreatic Islet Phenotype.
    Diabetes. 2021 Feb 2. pii: db20-0945. doi: 10.2337/db20-0945.
    PubMed     Abstract available

  21. GLIEBERMAN AL, Pope BD, Melton DA, Parker KK, et al
    Building Biomimetic Potency Tests for Islet Transplantation.
    Diabetes. 2021;70:347-363.
    PubMed     Abstract available

  22. PETRELLI A, Atkinson MA, Pietropaolo M, Giannoukakis N, et al
    Modulation of Leukocytes of the Innate Arm of the Immune System as a Potential Approach to Prevent the Onset and Progression of Type 1 Diabetes.
    Diabetes. 2021;70:313-322.
    PubMed     Abstract available

    January 2021
  23. ESPES D, Carlsson PO, Selvaraju RK, Rosestedt M, et al
    Longitudinal Assessment of (11)C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes.
    Diabetes. 2021 Jan 21. pii: db20-0776. doi: 10.2337/db20-0776.
    PubMed     Abstract available

  24. MHANNA V, Fourcade G, Barennes P, Quiniou V, et al
    Impaired Activated/Memory Regulatory T Cell Clonal Expansion Instigates Diabetes in NOD Mice.
    Diabetes. 2021 Jan 21. pii: db20-0896. doi: 10.2337/db20-0896.
    PubMed     Abstract available

  25. FIRDESSA-FITE R, Johnson SN, Leon MA, Khosravi-Maharlooei M, et al
    Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes.
    Diabetes. 2021 Jan 19. pii: db20-0845. doi: 10.2337/db20-0845.
    PubMed     Abstract available

  26. ROSS JJ, Wasserfall CH, Bacher R, Perry DJ, et al
    Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size.
    Diabetes. 2021 Jan 13. pii: db20-0995. doi: 10.2337/db20-0995.
    PubMed     Abstract available

  27. WILLIAMS MD, Bacher R, Perry DJ, Grace CR, et al
    Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis.
    Diabetes. 2021 Jan 8. pii: db20-0937. doi: 10.2337/db20-0937.
    PubMed     Abstract available

  28. HAUKKA J, Sandholm N, Valo E, Forsblom C, et al
    Novel Linkage Peaks Discovered for Diabetic Nephropathy in Individuals With Type 1 Diabetes.
    Diabetes. 2021 Jan 7. pii: db20-0158. doi: 10.2337/db20-0158.
    PubMed     Abstract available

  29. RODRIGUEZ-CALVO T, Krogvold L, Amirian N, Dahl-Jorgensen K, et al
    One in Ten CD8+ Cells in the Pancreas of Living Individuals With Recent Onset Type 1 Diabetes Recognizes the Preproinsulin Epitope PPI15-24.
    Diabetes. 2021 Jan 7. pii: db20-0908. doi: 10.2337/db20-0908.
    PubMed     Abstract available

    December 2020
  30. SNOWHITE I, Pastori R, Sosenko J, Cayetano SM, et al
    Baseline Assessment of Circulating microRNAs Near Diagnosis of Type 1 Diabetes Predicts Future Stimulated Insulin Secretion.
    Diabetes. 2020 Dec 4. pii: db20-0817. doi: 10.2337/db20-0817.
    PubMed     Abstract available

  31. BARRETT HL, Donaghue KC, Forbes JM
    Going in Early: Hypoxia as a Target for Kidney Disease Prevention in Diabetes?
    Diabetes. 2020;69:2578-2580.

  32. AZOURY ME, Tarayrah M, Afonso G, Pais A, et al
    Peptides Derived From Insulin Granule Proteins Are Targeted by CD8(+) T Cells Across MHC Class I Restrictions in Humans and NOD Mice.
    Diabetes. 2020;69:2678-2690.
    PubMed     Abstract available

    November 2020
  33. SODRE FMC, Bissenova S, Bruggeman Y, Tilvawala R, et al
    Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice.
    Diabetes. 2020 Nov 17. pii: db20-0421. doi: 10.2337/db20-0421.
    PubMed     Abstract available

  34. FLOYEL T, Meyerovich K, Prause MC, Kaur S, et al
    SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates beta-Cell Apoptosis and Glycaemic Control in Newly Diagnosed Patients.
    Diabetes. 2020 Nov 17. pii: db20-0092. doi: 10.2337/db20-0092.
    PubMed     Abstract available

  35. SHA S, Pearson JA, Peng J, Hu Y, et al
    TLR9-Deficiency in B Cells Promotes Immune Tolerance via IL-10 in a Type 1 Diabetes Mouse Model.
    Diabetes. 2020 Nov 5. pii: db20-0373. doi: 10.2337/db20-0373.
    PubMed     Abstract available

  36. ADVANI A
    Acute Kidney Injury: A Bona Fide Complication of Diabetes.
    Diabetes. 2020;69:2229-2237.
    PubMed     Abstract available

    October 2020
  37. RUSSO F, Citro A, Squeri G, Sanvito F, et al
    InsB9-23 Gene Transfer To Hepatocytes-Based Combined Therapy Abrogates Recurrence of Type-1 Diabetes After Islet Transplantation.
    Diabetes. 2020 Oct 29. pii: db19-1249. doi: 10.2337/db19-1249.
    PubMed     Abstract available

  38. THAYER TC, Davies J, Pearson JA, Hanna SJ, et al
    Differentiating MHC-Dependent and -Independent Mechanisms of Lymph Node Stromal Cell Regulation of Proinsulin-Specific CD8(+) T-Cells in type 1 Diabetes.
    Diabetes. 2020 Oct 29. pii: db19-1050. doi: 10.2337/db19-1050.
    PubMed     Abstract available

  39. LI Q, Liu X, Yang J, Erlund I, et al
    Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: the TEDDY Study.
    Diabetes. 2020 Oct 26. pii: db20-0696. doi: 10.2337/db20-0696.
    PubMed     Abstract available

    September 2020
  40. THIEM K, van Dierendonck XAMH, Janssen AWM, Boogaard JP, et al
    A High Glycemic Burden Relates to Functional and Metabolic Alterations of Human Monocytes in Patients with Type 1 Diabetes.
    Diabetes. 2020 Sep 25. pii: db20-0568. doi: 10.2337/db20-0568.
    PubMed     Abstract available

    August 2020
  41. ZHAO LP, Papadopoulos GK, Kwok WW, Moustakas AK, et al
    Next Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes.
    Diabetes. 2020 Aug 31. pii: db20-0374. doi: 10.2337/db20-0374.
    PubMed     Abstract available

  42. BUZZETTI R, Tuomi T, Mauricio D, Pietropaolo M, et al
    Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel.
    Diabetes. 2020 Aug 26. pii: dbi20-0017. doi: 10.2337/dbi20-0017.
    PubMed     Abstract available

  43. AHLQVIST E, Prasad RB, Groop L
    Subtypes of Type 2 Diabetes Determined From Clinical Parameters.
    Diabetes. 2020 Aug 25. pii: dbi20-0001. doi: 10.2337/dbi20-0001.
    PubMed     Abstract available

  44. FILIP P, Canna A, Moheet A, Bednarik P, et al
    Structural Alterations in Deep Brain Structures in Type 1 Diabetes.
    Diabetes. 2020 Aug 24. pii: db19-1100. doi: 10.2337/db19-1100.
    PubMed     Abstract available

  45. JAFFA MA, Bebu I, Luttrell D, Braffett BH, et al
    Longitudinal Plasma Kallikrein Levels and Their Association with the Risk of Cardiovascular Disease Outcomes in Type 1 Diabetes in DCCT/EDIC.
    Diabetes. 2020 Aug 21. pii: db20-0427. doi: 10.2337/db20-0427.
    PubMed     Abstract available

  46. BONE RN, Oyebamiji O, Talware S, Selvaraj S, et al
    A Computational Approach for Defining a Signature of beta-Cell Golgi Stress in Diabetes Mellitus.
    Diabetes. 2020 Aug 20. pii: db20-0636. doi: 10.2337/db20-0636.
    PubMed     Abstract available

    July 2020
  47. CUROVIC VR, Suvitaival T, Mattila I, Ahonen L, et al
    Circulating Metabolites and Lipids are Associated to Diabetic Retinopathy in Individuals With Type 1 Diabetes.
    Diabetes. 2020 Jul 31. pii: db20-0104. doi: 10.2337/db20-0104.
    PubMed     Abstract available

  48. VINOVSKIS C, Li LP, Prasad P, Tommerdahl K, et al
    Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes.
    Diabetes. 2020 Jul 31. pii: db20-0457. doi: 10.2337/db20-0457.
    PubMed     Abstract available

  49. KRAMER F, Martinson AM, Papayannopoulou T, Kanter JE, et al
    Myocardial Infarction Does not Accelerate Atherosclerosis in a Mouse Model of Type 1 Diabetes.
    Diabetes. 2020 Jul 21. pii: db20-0152. doi: 10.2337/db20-0152.
    PubMed     Abstract available

  50. JAMES EA, Mallone R, Kent SC, DiLorenzo TP, et al
    T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal.
    Diabetes. 2020;69:1311-1335.
    PubMed     Abstract available

  51. ARRIBAS-LAYTON D, Guyer P, Delong T, Dang M, et al
    Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01.
    Diabetes. 2020;69:1492-1502.
    PubMed     Abstract available

    June 2020
  52. BARRA JM, Kozlovskaya V, Kharlampieva E, Tse HM, et al
    Localized Immunosuppression with Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection.
    Diabetes. 2020 Jun 25. pii: db20-0248. doi: 10.2337/db20-0248.
    PubMed     Abstract available

    May 2020
  53. FOLAND-ROSS LC, Tong G, Mauras N, Cato A, et al
    Brain Function Differences in Children With Type 1 Diabetes: An fMRI Study of Working Memory.
    Diabetes. 2020 May 29. pii: db20-0123. doi: 10.2337/db20-0123.
    PubMed     Abstract available

  54. SIMMONS KM, Mitchell AM, Alkanani AA, McDaniel KA, et al
    Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02.
    Diabetes. 2020 May 21. pii: db20-0038. doi: 10.2337/db20-0038.
    PubMed     Abstract available

  55. SOSENKO JM, Skyler JS, Herold KC, Schatz DA, et al
    Slowed Metabolic Decline after One Year of Oral Insulin Treatment among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 and TrialNet Oral Insulin Prevention Trials.
    Diabetes. 2020 May 21. pii: db20-0166. doi: 10.2337/db20-0166.
    PubMed     Abstract available

  56. LU G, Rausell-Palamos F, Zhang J, Zheng Z, et al
    Dextran Sulfate Protects Pancreatic beta-Cells, Reduces Autoimmunity and Ameliorates Type 1 Diabetes.
    Diabetes. 2020 May 7. pii: db19-0725. doi: 10.2337/db19-0725.
    PubMed     Abstract available

  57. GREGORY JM, Cherrington AD, Moore DJ
    The Peripheral Peril: Injected Insulin Induces Insulin Insensitivity in Type 1 Diabetes.
    Diabetes. 2020;69:837-847.
    PubMed     Abstract available

    April 2020
  58. BOLO NR, Jacobson AM, Musen G, Keshavan MS, et al
    Acute Hyperglycemia Increases Brain Pregenual Anterior Cingulate Cortex Glutamate Concentrations in Type 1 Diabetes Mellitus.
    Diabetes. 2020 Apr 15. pii: db19-0936. doi: 10.2337/db19-0936.
    PubMed     Abstract available

  59. ZHAO LP, Papadopoulos GK, Kwok WW, Moustakas AK, et al
    Motifs of Three HLA-DQ Amino Acid Residues (alpha44, beta57, beta135) Capture Full Association with the Risk of Type 1 Diabetes in DQ2 and DQ8 Children.
    Diabetes. 2020 Apr 3. pii: db20-0075. doi: 10.2337/db20-0075.
    PubMed     Abstract available

    March 2020
  60. CARI L, Montanucci P, Basta G, Petrillo MG, et al
    Microencapsulated G3C hybridoma cell graft delays the onset of spontaneous diabetes in NOD mice by an expansion of Gitr(+) Treg cells.
    Diabetes. 2020 Mar 13. pii: db19-0087. doi: 10.2337/db19-0087.
    PubMed     Abstract available

  61. MILLER RG, Orchard TJ
    Understanding Metabolic Memory: A Tale of Two Studies.
    Diabetes. 2020;69:291-299.
    PubMed     Abstract available

  62. BETTINI M, Scavuzzo MA, Liu B, Kolawole E, et al
    A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells.
    Diabetes. 2020;69:392-400.
    PubMed     Abstract available

    February 2020
  63. KUCK JL, Bonhof GJ, Strom A, Zaharia OP, et al
    Impairment in Baroreflex Sensitivity in Recent-Onset Type 2 Diabetes Without Progression Over 5 Years.
    Diabetes. 2020 Feb 21. pii: db19-0990. doi: 10.2337/db19-0990.
    PubMed     Abstract available

  64. STANKUTE I, Verkauskiene R, Blouin JL, Klee P, et al
    Systematic Genetic Study of Diabetic Youth in a Single Country Reveals the Prevalence of Diabetes Subtypes, Novel Candidate Genes, and Response to Precision Therapy.
    Diabetes. 2020 Feb 21. pii: db19-0974. doi: 10.2337/db19-0974.
    PubMed     Abstract available

  65. BRAFFETT BH, Gubitosi-Klug RA, Albers JW, Feldman EL, et al
    Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study.
    Diabetes. 2020 Feb 12. pii: db19-1046. doi: 10.2337/db19-1046.
    PubMed     Abstract available

  66. LI Q, Parikh H, Butterworth MD, Lernmark A, et al
    Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study.
    Diabetes. 2020 Feb 6. pii: db19-0756. doi: 10.2337/db19-0756.
    PubMed     Abstract available

    January 2020
  67. FORGETTA V, Manousaki D, Istomine R, Ross S, et al
    Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes.
    Diabetes. 2020 Jan 31. pii: db19-0831. doi: 10.2337/db19-0831.
    PubMed     Abstract available

  68. MOCHIDA T, Ueno H, Yamazoe N, Hiyoshi H, et al
    Insulin-Deficient Diabetic Condition Upregulates Insulin Secreting Capacity of Human iPSC-Derived Pancreatic Endocrine Progenitor Cells After Implantation in Mice.
    Diabetes. 2020 Jan 31. pii: db19-0728. doi: 10.2337/db19-0728.
    PubMed     Abstract available

  69. JORNS A J A, Wedekind D W D, Jahne J J J, Lenzen S L S, et al
    Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared to Type 1 Diabetes Mellitus.
    Diabetes. 2020 Jan 23. pii: db19-0865. doi: 10.2337/db19-0865.
    PubMed     Abstract available

  70. KNOOP J, Eugster A, Gavrisan A, Lickert R, et al
    Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4(+) T Cells in Offspring.
    Diabetes. 2020 Jan 2. pii: db19-0751. doi: 10.2337/db19-0751.
    PubMed     Abstract available

    December 2019
  71. EID SA, El Massry M, Hichor M, Haddad M, et al
    Targeting the NADPH Oxidase-4 and Liver X Receptor Signaling Axis Preserve Schwann Cell Integrity in Diabetic Mice.
    Diabetes. 2019 Dec 27. pii: db19-0517. doi: 10.2337/db19-0517.
    PubMed     Abstract available

  72. SHAPIRO MR, Wasserfall CH, McGrail SM, Posgai AL, et al
    Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.
    Diabetes. 2019 Dec 11. pii: db19-0942. doi: 10.2337/db19-0942.
    PubMed     Abstract available

  73. LIU B, Hood JD, Kolawole EM, Woodruff DM, et al
    A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery.
    Diabetes. 2019 Dec 5. pii: db19-0399. doi: 10.2337/db19-0399.
    PubMed     Abstract available

    November 2019
  74. FROHNERT BI, Webb-Robertson BJ, Bramer LM, Reehl SM, et al
    Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources.
    Diabetes. 2019 Nov 18. pii: db18-1263. doi: 10.2337/db18-1263.
    PubMed     Abstract available

  75. CABELLO-KINDELAN C, Mackey S, Sands A, Rodriguez J, et al
    Immunomodulation Followed By Antigen-Specific Treg Infusion Controls Islet Autoimmunity.
    Diabetes. 2019 Nov 11. pii: db19-0061. doi: 10.2337/db19-0061.
    PubMed     Abstract available

    October 2019
  76. LI M, Wang S, Xu K, Chen Y, et al
    High prevalence of a monogenic cause in Han Chinese diagnosed with type 1 diabetes, partly driven by non-syndromic recessive WFS1 mutations.
    Diabetes. 2019 Oct 28. pii: db19-0510. doi: 10.2337/db19-0510.
    PubMed     Abstract available

  77. KUSMARTSEVA I, Beery M, Hiller H, Padilla M, et al
    Temporal Analysis of Amylase Expression in Control, Autoantibody Positive, and Type 1 Diabetes Pancreatic Tissues.
    Diabetes. 2019 Oct 9. pii: db19-0554. doi: 10.2337/db19-0554.
    PubMed     Abstract available

  78. KOSKINEN MK, Mikk ML, Laine AP, Lempainen J, et al
    Longitudinal Pattern of First-Phase Insulin Response Is Associated with Genetic Variants Outside the Class II HLA Region in Children with Multiple Autoantibodies.
    Diabetes. 2019 Oct 7. pii: db19-0329. doi: 10.2337/db19-0329.
    PubMed     Abstract available

  79. SHARMA S, Pettus J, Gottschalk M, Abe B, et al
    Single-Cell Analysis of CD4 T Cells in Type 1 Diabetes: From Mouse to Man, How to Perform Mechanistic Studies.
    Diabetes. 2019;68:1886-1891.
    PubMed     Abstract available

    September 2019
  80. FLORIJN BW, Duijs JMGJ, Levels JH, Dallinga-Thie GM, et al
    Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic miRNAs Between Extracellular Vesicles, HDL and Ago-2.
    Diabetes. 2019 Sep 10. pii: db18-1360. doi: 10.2337/db18-1360.
    PubMed     Abstract available

    August 2019
  81. VUORI N, Sandholm N, Kumar A, Hietala K, et al
    CACNB2 is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes.
    Diabetes. 2019 Aug 22. pii: db19-0130. doi: 10.2337/db19-0130.
    PubMed     Abstract available

  82. BADILLO FG, Tegou FZ, Abreu MM, Masina R, et al
    CCL21 Expression in beta-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice.
    Diabetes. 2019 Aug 1. pii: db19-0239. doi: 10.2337/db19-0239.
    PubMed     Abstract available

  83. UNANUE ER, Wan X
    The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity.
    Diabetes. 2019;68:1544-1551.
    PubMed     Abstract available

  84. In This Issue of Diabetes.
    Diabetes. 2019;68:1539-1540.

    July 2019
  85. MATHEW AV, Jaiswal M, Ang L, Michailidis G, et al
    Impaired Amino Acid and TCA Metabolism and Cardiovascular Autonomic Neuropathy Progression in Type 1 Diabetes.
    Diabetes. 2019 Jul 23. pii: db19-0145. doi: 10.2337/db19-0145.
    PubMed     Abstract available

  86. KALLIONPAA H, Somani J, Tuomela S, Ullah U, et al
    Early Detection of Peripheral Blood Cell Signature in Children Developing Beta-Cell Autoimmunity at a Young Age.
    Diabetes. 2019 Jul 16. pii: db19-0287. doi: 10.2337/db19-0287.
    PubMed     Abstract available

  87. SOFI MH, Johnson BM, Gudi RR, Jolly A, et al
    Polysaccharide A-Dependent Opposing Effects of Mucosal and Systemic Exposures to Human Gut Commensal Bacteroides Fragilis in Type 1 Diabetes.
    Diabetes. 2019 Jul 16. pii: db19-0211. doi: 10.2337/db19-0211.
    PubMed     Abstract available

  88. AHMED S, Cerosaletti K, James E, Long SA, et al
    Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
    Diabetes. 2019;68:1366-1379.
    PubMed     Abstract available

    June 2019
  89. LOPES-VIRELLA MF, Bebu I, Hunt KJ, Virella G, et al
    Immune Complexes and the Risk of CVD in Type 1 Diabetes.
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  90. BAKER RL, Rihanek M, Hohenstein AC, Nakayama M, et al
    Hybrid Insulin Peptides are Autoantigens in Type 1 Diabetes.
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  91. ACEVEDO-CALADO MJ, Pietropaolo SL, Morran MP, Schnell S, et al
    Autoantibodies Directed to a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes.
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  92. In This Issue of Diabetes.
    Diabetes. 2019;68:1097-1098.

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    Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.
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  95. ZHAO LP, Papadopoulos GK, Kwok B, Xu B, et al
    Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes.
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  96. PURCELL AW, Sechi S, DiLorenzo TP
    The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes.
    Diabetes. 2019;68:879-886.
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    Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data.
    Diabetes. 2019 Apr 9. pii: db19-0057. doi: 10.2337/db19-0057.
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  98. JOHNSON MB, De Franco E, Atma W Greeley S, Letourneau LR, et al
    Trisomy 21 is a Cause of Permanent Neonatal Diabetes that is Autoimmune but not HLA Associated.
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  99. AYDEMIR O, Noble JA, Bailey J, Lernmark A, et al
    Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes.
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  100. WIEDE F, Brodnicki T, Goh PK, Leong YA, et al
    T Cell-Specific PTPN2-Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Co-Morbidities.
    Diabetes. 2019 Apr 1. pii: db18-1362. doi: 10.2337/db18-1362.
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    March 2019
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    Cardiac Autonomic Function is Associated With Myocardial Flow Reserve in Type 1 Diabetes.
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  102. RUSSELL MA, Redick SD, Blodgett DM, Richardson SJ, et al
    HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of islet beta-Cells from Donors with Type 1 Diabetes.
    Diabetes. 2019 Mar 4. pii: db18-0686. doi: 10.2337/db18-0686.
    PubMed     Abstract available

  103. THORENS B
    Targeting the Brain to Cure Type 2 Diabetes.
    Diabetes. 2019;68:476-478.

  104. In This Issue of Diabetes.
    Diabetes. 2019;68:469-470.

    February 2019
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    Glucose Metabolism is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes Mellitus.
    Diabetes. 2019 Feb 14. pii: db18-0981. doi: 10.2337/db18-0981.
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  106. FABBRI M, Frixou M, Degano M, Fousteri G, et al
    Type 1 Diabetes in STAT Protein Family Mutations: Regulating the Th17/Treg Equilibrium and Beyond.
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    January 2019
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    Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes.
    Diabetes. 2019 Jan 23. pii: db18-0573. doi: 10.2337/db18-0573.
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  108. HIPPICH M, Beyerlein A, Hagopian WA, Krischer JP, et al
    Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families.
    Diabetes. 2019 Jan 17. pii: db18-0882. doi: 10.2337/db18-0882.
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  109. VAN LUMMEL M, Buis DTP, Ringeling C, de Ru AH, et al
    Epitope Stealing as Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.
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    Structural and Functional Abnormalities of the Primary Somatosensory Cortex in Diabetic Peripheral Neuropathy: A Multimodal MRI Study.
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  111. In This Issue of Diabetes.
    Diabetes. 2019;68:1-2.

  112. COURTY E, Besseiche A, Do TTH, Liboz A, et al
    Adaptive beta-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance.
    Diabetes. 2019;68:95-108.
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    Glycemic Variability and Brain Glucose Levels in Type 1 Diabetes.
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    December 2018
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    Low Level Insulin Content Within Abundant Non-Beta Islet Endocrine Cells in Long-Standing Type 1 Diabetes.
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    A genome-Wide Association Study Confirming a Strong Effect of HLA and Identifying Variants in CSAD/lnc-ITGB7-1 on Chromosome 12q13.13 Associated with Susceptibility to Fulminant Type 1 Diabetes.
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    November 2018
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    NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.
    Diabetes. 2018 Nov 13. pii: db18-0845. doi: 10.2337/db18-0845.
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  117. MILLER RG, Costacou T, Orchard TJ
    Risk Factor Modeling for Cardiovascular Disease in Type I Diabetes in the Pittsburgh Epidemiology of Diabetes Complications (EDC) Study: A Comparison to the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complicati
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    VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy.
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  119. BUITINGA M, Callebaut A, Marques Camara Sodre F, Crevecoeur I, et al
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  121. In This Issue of Diabetes.
    Diabetes. 2018;67:2127-2128.

    October 2018
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    Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children.
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    September 2018
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    The Ascending GLP-1 Road From Clinical Safety to Reduction of Cardiovascular Complications.
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    PubMed     Abstract available

  125. ACCILI D
    Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture.
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    August 2018
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    Beta Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes.
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  128. SALAMI F, Lee HS, Freyhult E, Larsson HE, et al
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    Extending Remission and Reversing New Onset Type 1 Diabetes by Targeted Ablation of Autoreactive T Cells.
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    Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization.
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    July 2018
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    Islet-Derived eATP Fuels Autoreactive CD8(+) Cells and Facilitates the Onset of Type 1 Diabetes.
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    Validation of (111)In-Exendin SPECT for the Determination of the Beta Cell Mass in BioBreeding Diabetes Prone Rats.
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    Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice.
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    Learning From Past Failures of Oral Insulin Trials.
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  140. In This Issue of Diabetes.
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    Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway.
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    May 2018
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    Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
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  143. COOPER ME, El-Osta A, Allen TJ, Watson AMD, et al
    Metabolic Karma-The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture.
    Diabetes. 2018;67:785-790.
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  144. In This Issue of Diabetes.
    Diabetes. 2018;67:783-784.

    April 2018
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    Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.
    Diabetes. 2018 Apr 13. pii: db17-1166. doi: 10.2337/db17-1166.
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  146. SUN H, Lee P, Yan C, Gao N, et al
    Inhibition of Soluble Epoxide Hydrolase 2 Ameliorates Diabetic Keratopathy and Impaired Wound Healing in Mouse Corneas.
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    Highly Proliferative alpha-Cell-Related Islet Endocrine Cells in Human Pancreata.
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    March 2018
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    Altered Brain Dynamics in Patients with Type 1 Diabetes During Working Memory Processing.
    Diabetes. 2018 Mar 12. pii: db17-1382. doi: 10.2337/db17-1382.
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  149. VIGNALI D, Cantarelli E, Bordignon C, Canu A, et al
    Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients with Type 1 Diabetes.
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    February 2018
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    Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice.
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  151. RACINE JJ, Stewart I, Ratiu J, Christianson G, et al
    Improved Murine-MHC-Deficient HLA-Transgenic NOD-Mouse Models for Type 1 Diabetes Therapy Development.
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  152. SATAKE E, Pezzolesi MG, Md Dom ZI, Smiles AM, et al
    Circulating miRNA Profiles Associated With Hyperglycemia in Patients With Type 1 Diabetes Mellitus.
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    In Vivo Visualization of beta-Cells by Targeting of GPR44.
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    Engineering Glucose Responsiveness Into Insulin.
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    January 2018
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    Loss of B Cell Anergy in Type 1 Diabetes is Associated with High Risk HLA and non-HLA Disease Susceptibility Alleles.
    Diabetes. 2018 Jan 17. pii: db17-0937. doi: 10.2337/db17-0937.
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  156. KRONENBERG-VERSTEEG D, Eichmann M, Russell MA, de Ru A, et al
    Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes.
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  157. LI J, Huynh P, Dai A, Wu T, et al
    Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
    Diabetes. 2018 Jan 8. pii: db17-0134. doi: 10.2337/db17-0134.
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  158. JOHNSON MB, De Franco E, Allen HL, Al Senani A, et al
    Erratum. Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes. Diabetes 2017;66:2316-2322.
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  159. KALYANARAMAN H, Schwaerzer G, Ramdani G, Castillo F, et al
    Potein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes.
    Diabetes. 2018 Jan 4. pii: db17-0965. doi: 10.2337/db17-0965.
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    December 2017
    Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No.
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    November 2017
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    Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents.
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    October 2017
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    Thioredoxin-1 Overexpression in the Ventromedial Nucleus of the Hypothalamus (VMH) Preserves the Counterregulatory Response to Hypoglycemia During Type 1 Diabetes Mellitus in Male Rats.
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  163. GU J, Yan X, Dai X, Wang Y, et al
    Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts.
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  164. MILLER WP, Yang C, Mihailescu ML, Moore JA, et al
    Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes.
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    Effect of Exercise-Induced Lactate Elevation on Brain Lactate Levels During Hypoglycemia in Patients with Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
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    Recessively Inherited Lrba Mutations Cause Autoimmunity Presenting as Neonatal Diabetes.
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    Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart.
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    October 2016
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    September 2016
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    July 2016
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    May 2016
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