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  Autoimmune Disorders

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Articles published in Diabetes

Retrieve available abstracts of 144 articles:
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Single Articles


    January 2025
  1. JIA X, Wenzlau JM, Zhang C, Dong F, et al
    Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 (IA-2) with Clinical Onset of Type 1 Diabetes.
    Diabetes. 2025 Jan 16:db240571. doi: 10.2337/db24-0571.
    PubMed     Abstract available


  2. HOHENSTEIN AC, Gallegos J, Dang M, Groegler J, et al
    Novel T Cell reactivities to Hybrid Insulin Peptides in Islet Autoantibody-Positive At-Risk Subjects.
    Diabetes. 2025 Jan 16:db240611. doi: 10.2337/db24-0611.
    PubMed     Abstract available


    November 2024
  3. LUCKETT AM, Hawkes G, Green HD, De Franco E, et al
    Type 1 diabetes genetic risk contributes to phenotypic presentation in monogenic autoimmune diabetes.
    Diabetes. 2024 Nov 12:db240485. doi: 10.2337/db24-0485.
    PubMed     Abstract available


    October 2024
  4. MALLONE R, Sims E, Achenbach P, Mathieu C, et al
    Emerging concepts and success stories in type 1 diabetes research: a roadmap for a bright future.
    Diabetes. 2024 Oct 24:db240439. doi: 10.2337/db24-0439.
    PubMed     Abstract available


  5. BARRA JM, Kratz AT, Castro-Gutierrez R, Proia J, et al
    Cryopreservation of Stem Cell-Derived beta-Like Cells Enriches for Insulin-Producing Cells With Improved Function.
    Diabetes. 2024;73:1687-1696.
    PubMed     Abstract available


    September 2024
  6. ALMUTAIRI A, White TD, Stephenson DJ, Stephenson BD, et al
    Selective Reduction of Ca2+-Independent Phospholipase A2beta (iPLA2beta)-Derived Lipid Signaling from Macrophages Mitigates Type 1 Diabetes Development.
    Diabetes. 2024 Sep 16:db230770. doi: 10.2337/db23-0770.
    PubMed     Abstract available


  7. LIU Y, Wang S, Wang Z, Yu J, et al
    Recent Progress in Glucose-Responsive Insulin.
    Diabetes. 2024;73:1377-1388.
    PubMed     Abstract available


    August 2024
  8. GREENBAUM CJ, Nepom GT, Wood-Heickman LK, Wherrett DK, et al
    Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop.
    Diabetes. 2024 Aug 21:dbi240020. doi: 10.2337/dbi24-0020.
    PubMed     Abstract available


  9. SHEN Y, Shi R, Lu S, Wang Y, et al
    Role of Peptidyl arginine deiminase 4-dependent macrophage extracellular traps formation on Type 1 Diabetes pathogenesis.
    Diabetes. 2024 Aug 13:db231000. doi: 10.2337/db23-1000.
    PubMed     Abstract available


  10. MARTINO M, Galderisi A, Evans-Molina C, Dayan C, et al
    Revisiting the pattern of loss of beta-cell function in preclinical Type 1 Diabetes.
    Diabetes. 2024 Aug 6:db240163. doi: 10.2337/db24-0163.
    PubMed     Abstract available


    July 2024
  11. MANDUCHI E, Descamps HC, Schug J, Da T, et al
    No evidence for persistent enteroviral B infection of pancreatic islets in type 1 diabetic and pre-diabetic patients from RNA-Seq data.
    Diabetes. 2024 Jul 31:db240076. doi: 10.2337/db24-0076.
    PubMed     Abstract available


  12. GRACE SL, Gillespie KM, Williams CL, Lampasona V, et al
    Autoantibodies to truncated GAD(96-585) antigen stratify risk of early insulin requirement in adult-onset diabetes.
    Diabetes. 2024 Jul 8:db230980. doi: 10.2337/db23-0980.
    PubMed     Abstract available


  13. SUNILKUMAR S, Dennis MD
    REDD1 is a Promising Therapeutic Target to Combat the Development of Diabetic Complications: A Report on Research Supported by Pathway to Stop Diabetes.
    Diabetes. 2024 Jul 8:dbi240013. doi: 10.2337/dbi24-0013.
    PubMed     Abstract available


  14. KJELDSEN SAS, Richter MM, Jensen NJ, Nilsson MSD, et al
    Glucagon resistance in individuals with obesity and hepatic steatosis can be measured using the GLUSENTIC test and index.
    Diabetes. 2024 Jul 8:db230858. doi: 10.2337/db23-0858.
    PubMed     Abstract available


  15. SCHRODERUS AM, Pitkanen V, Ekman I, Stevens D, et al
    Temporal Alterations in CD8+ T Cells During the Progression from Stage 1 to Stage 3 Type 1 Diabetes.
    Diabetes. 2024 Jul 5:db240159. doi: 10.2337/db24-0159.
    PubMed     Abstract available


    June 2024
  16. LESLIE KA, Lekka C, Richardson SJ, Russell MA, et al
    Regulation of STAT1 signalling in human pancreatic beta-cells by the lysine deacetylase, HDAC6; a new therapeutic opportunity in type 1 diabetes?
    Diabetes. 2024 Jun 13:db240008. doi: 10.2337/db24-0008.
    PubMed     Abstract available


    May 2024
  17. YANG Z, Zhang Z, Li L, Jing Z, et al
    Bioengineered Artificial Extracellular Vesicles Presenting PD-L1 and Gal-9 Ameliorate New-onset Type 1 Diabetes.
    Diabetes. 2024 May 21:db230987. doi: 10.2337/db23-0987.
    PubMed     Abstract available


  18. FRORUP C, Jensen MH, Haupt-Jorgensen M, Buschard K, et al
    Elevated cathepsin S serum levels in new-onset type 1 diabetes and autoantibody-positive siblings.
    Diabetes. 2024 May 3:db230911. doi: 10.2337/db23-0911.
    PubMed     Abstract available


    April 2024
  19. EVANS-MOLINA C
    The Ailing beta-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture.
    Diabetes. 2024;73:545-553.
    PubMed     Abstract available


  20. DRAWSHY Z, Neiman D, Fridlich O, Peretz A, et al
    DNA Methylation-Based Assessment of Cell Composition in Human Pancreas and Islets.
    Diabetes. 2024;73:554-564.
    PubMed     Abstract available


    March 2024
  21. KIM YK, Kim YR, Wells KL, Sarbaugh D, et al
    PTPN2 Regulates Metabolic Flux to Affect beta-Cell Susceptibility to Inflammatory Stress.
    Diabetes. 2024;73:434-447.
    PubMed     Abstract available


    February 2024
  22. KASINATHAN D, Guo Z, Sarver DC, Wong GW, et al
    Cell-surface ZnT8 antibody prevents and reverses autoimmune diabetes in mice.
    Diabetes. 2024 Feb 22:db230568. doi: 10.2337/db23-0568.
    PubMed     Abstract available


  23. CALLEBAUT A, Guyer P, Derua R, Buitinga M, et al
    CD4+ T cells from individuals with type 1 diabetes respond to a novel class of deamidated peptides formed in pancreatic islets.
    Diabetes. 2024 Feb 22:db230588. doi: 10.2337/db23-0588.
    PubMed     Abstract available


  24. LATRES E, Greenbaum CJ, Oyaski ML, Dayan CM, et al
    Evidence for C-peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes.
    Diabetes. 2024 Feb 13:dbi230012. doi: 10.2337/dbi23-0012.
    PubMed     Abstract available


    January 2024
  25. CALLEBAUT A, Guyer P, Baker RL, Gallegos JB, et al
    An Insulin-Chromogranin A Hybrid Peptide activates DR11 restricted T cells in human type 1 diabetes.
    Diabetes. 2024 Jan 31:db230622. doi: 10.2337/db23-0622.
    PubMed     Abstract available


  26. CIOU JJ, Chien MW, Hsu CY, Liu YW, et al
    Excess Salt Intake Activates IL-21-dominant Autoimmune Diabetogenesis via A Saltregulated Ste20-related Proline/alanine-rich Kinase in CD4 T Cells.
    Diabetes. 2024 Jan 19:db230599. doi: 10.2337/db23-0599.
    PubMed     Abstract available


  27. WYATT RC, Grace SL, Brigatti C, Marzinotto I, et al
    Improved specificity of glutamate decarboxylase 65 autoantibody measurement using luciferase-based immunoprecipitation system (LIPS) assays.
    Diabetes. 2024 Jan 17:db230550. doi: 10.2337/db23-0550.
    PubMed     Abstract available


    November 2023
  28. KUGATHASAN L, Sridhar VS, Lovblom LE, Matta S, et al
    Interactive effects of Empagliflozin and Hyperglycemia on Urinary Amino Acids in Individuals with Type 1 Diabetes.
    Diabetes. 2023 Nov 28:db230694. doi: 10.2337/db23-0694.
    PubMed     Abstract available


  29. LAI SWT, Hernandez-Castillo C, De Jesus Lopez Gonzalez E, Zoukari T, et al
    Methylglyoxal adducts are prognostic biomarkers for diabetic kidney disease in patients with type 1 diabetes.
    Diabetes. 2023 Nov 15:db230277. doi: 10.2337/db23-0277.
    PubMed     Abstract available


  30. ILONEN J, Kiviniemi M, El-Amir MI, Nygard L, et al
    Increased Frequency of the HLA-DRB1*04:04-DQA1*03-DQB1*03:02 Haplotype among HLA-DQB1*06:02 Positive Children with Type 1 Diabetes.
    Diabetes. 2023 Nov 7:db230387. doi: 10.2337/db23-0387.
    PubMed     Abstract available


  31. ELGAMAL RM, Kudtarkar P, Melton RL, Mummey HM, et al
    An Integrated Map of Cell Type-Specific Gene Expression in Pancreatic Islets.
    Diabetes. 2023;72:1719-1728.
    PubMed     Abstract available


    October 2023
  32. WRIGHT JJ, Eskaros A, Windon A, Bottino R, et al
    Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.
    Diabetes. 2023 Oct 26:db230009. doi: 10.2337/db23-0009.
    PubMed     Abstract available


  33. ZOU W, Chezhian J, Yu T, Liu W, et al
    Dissecting the roles of the nuclear and mitochondrial genomes in a mouse model of autoimmune diabetes.
    Diabetes. 2023 Oct 17:db230430. doi: 10.2337/db23-0430.
    PubMed     Abstract available


  34. XU G, Chen J, Lu B, Sethupathy P, et al
    Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes beta-Cell IGF-I Signaling.
    Diabetes. 2023;72:1460-1469.
    PubMed     Abstract available


    September 2023
  35. OBERHAUSER SS, l'Allemand D, Willems EP, Gozzi T, et al
    The slowing of peripheral nerve conduction velocity in children and adolescents with type 1 diabetes is predicted by glucose fluctuations.
    Diabetes. 2023 Sep 12:db230063. doi: 10.2337/db23-0063.
    PubMed     Abstract available


    August 2023
  36. FOTINO C, Molano RD, Nasr MB, Umland O, et al
    Reversal of experimental autoimmune diabetes with a sCD39/anti-CD3 treatment.
    Diabetes. 2023 Aug 25:db230178. doi: 10.2337/db23-0178.
    PubMed     Abstract available


    July 2023
  37. SASSI G, Licata G, Ventriglia G, Wouters A, et al
    A plasma miR-193b-365 signature combined with age and glycemic status predicts response to Lactococcus lactis-based antigen-specific immunotherapy in new-onset type 1 diabetes.
    Diabetes. 2023 Jul 26:db220852. doi: 10.2337/db22-0852.
    PubMed     Abstract available


  38. WRETLIND A, Curovic VR, Suvitaival T, Theilade S, et al
    Ceramides as risk markers for future cardiovascular events and all-cause mortality in long-standing type 1 diabetes.
    Diabetes. 2023 Jul 21:db230052. doi: 10.2337/db23-0052.
    PubMed     Abstract available


  39. SCHON M, Zaharia OP, Strassburger K, Kupriyanova Y, et al
    Intramyocellular Triglyceride Content During the Early Course of Type 1 and Type 2 Diabetes Mellitus.
    Diabetes. 2023 Jul 21:db230353. doi: 10.2337/db23-0353.
    PubMed     Abstract available


  40. TANG Y, Ang L, Jaiswal M, Dillon BR, et al
    Cardiovascular autonomic neuropathy and risk of kidney function decline in type 1 and type 2 diabetes: findings from the PERL and ACCORD cohorts.
    Diabetes. 2023 Jul 19:db230247. doi: 10.2337/db23-0247.
    PubMed     Abstract available


    June 2023
  41. GITELMAN SE, Evans-Molina C, Guolo A, Mari A, et al
    ss-cell glucose sensitivity to assess changes in ss-cell function in recent onset stage 3 type 1 diabetes.
    Diabetes. 2023 Jun 27:db230196. doi: 10.2337/db23-0196.
    PubMed     Abstract available


  42. QURESHI FM, Panzer JK, Poder J, Malek TR, et al
    Immunotherapy With Low-Dose IL-2/CD25 Prevents beta-Cell Dysfunction and Dysglycemia in Prediabetic NOD Mice.
    Diabetes. 2023;72:769-780.
    PubMed     Abstract available


  43. ROJAS-CANALES D, Walters SN, Penko D, Cultrone D, et al
    Intracutaneous Transplantation of Islets Within a Biodegradable Temporizing Matrix as an Alternative Site for Islet Transplantation.
    Diabetes. 2023;72:758-768.
    PubMed     Abstract available


    May 2023
  44. POSTIC S, Pfabe J, Sarikas S, Ehall B, et al
    Tracking Ca2+ dynamics in NOD mouse islets during spontaneous diabetes development.
    Diabetes. 2023 May 31:db220952. doi: 10.2337/db22-0952.
    PubMed     Abstract available


  45. BODE K, MacDonald T, Stewart T, Mendez B, et al
    Protective Renalase-deficiency in beta cells shapes immune metabolism and function in autoimmune diabetes.
    Diabetes. 2023 May 22:db230030. doi: 10.2337/db23-0030.
    PubMed     Abstract available


  46. MONTEFUSCO L, Pastore I, Lunati ME, Fiorina P, et al
    Increased Risk of Diabetes and Diabetic Ketoacidosis Associated With COVID-19.
    Diabetes. 2023;72:560-561.
    PubMed    


    April 2023
  47. HSU CC, Fidler TP, Kanter JE, Kothari V, et al
    Hematopoietic NLRP3 and AIM2 inflammasomes promote diabetes-accelerated atherosclerosis, but increased necrosis is independent of pyroptosis.
    Diabetes. 2023 Apr 21:db220962. doi: 10.2337/db22-0962.
    PubMed     Abstract available


  48. JANSEN TJP, Buitinga M, Boss M, Nijhoff MF, et al
    Monitoring beta cell survival after intrahepatic islet transplantation using dynamic exendin PET imaging: a proof-of-concept study in individuals with type 1 diabetes.
    Diabetes. 2023 Apr 17:db220884. doi: 10.2337/db22-0884.
    PubMed     Abstract available


    March 2023
  49. XIE L, Lu W, Zhang Y, Deng L, et al
    Glucose-activated switch regulating insulin analogue secretion enables long-term precise glucose control in type 1 diabetes mice.
    Diabetes. 2023 Mar 13:db220860. doi: 10.2337/db22-0860.
    PubMed     Abstract available


    January 2023
  50. NJEIM R, Braych K, Ghadieh HE, Azar NS, et al
    VEGF-A: A NOVEL MECHANISTIC LINK BETWEEN CYP2C-DERIVED EET AND NOX4 IN DIABETIC KIDNEY DISEASE.
    Diabetes. 2023 Jan 20:db220636. doi: 10.2337/db22-0636.
    PubMed     Abstract available


  51. KAWATA S, Kozawa J, Yoneda S, Fujita Y, et al
    Inflammatory Cell Infiltration into Islets without PD-L1 Expression is Associated with the Development of Immune Checkpoint Inhibitor-Related Type 1 Diabetes in Genetically Susceptible Patients.
    Diabetes. 2023 Jan 19:db220557. doi: 10.2337/db22-0557.
    PubMed     Abstract available


    December 2022
  52. PETSIOU A, Vartholomatos G, Tsatsoulis A, Papadopoulos GK, et al
    Comment on Liu et al. Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple beta-Cell Peptides in Type 1 Diabetes. Diabetes 2022;71:722-732.
    Diabetes. 2022;71:e20-e21.
    PubMed    


  53. MISRA S, DiMeglio LA
    COVID-19 and Incident Type 1 Diabetes: Deciphering the Associations.
    Diabetes. 2022;71:2480-2482.
    PubMed    


  54. PIETROPAOLO M, Hotez P, Giannoukakis N
    Response to Comment on Pietropaolo et al. Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2- Infected Young Individuals: Is It Type 1 Diabetes? Diabetes 2022;71:2656-2663.
    Diabetes. 2022;71:e19.
    PubMed    


  55. HSU CK, Lai CC
    Comment on Pietropaolo et al. Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2-Infected Young Individuals: Is It Type 1 Diabetes? Diabetes 2022;71:2656-2663.
    Diabetes. 2022;71:e18.
    PubMed    


  56. SYREENI A, Dahlstrom EH, Hagg-Holmberg S, Forsblom C, et al
    Haptoglobin Genotype Does Not Confer a Risk of Stroke in Type 1 Diabetes.
    Diabetes. 2022;71:2728-2738.
    PubMed     Abstract available


  57. GOU W, Hua W, Swaby L, Cui W, et al
    Stem Cell Therapy Improves Human Islet Graft Survival in Mice via Regulation of Macrophages.
    Diabetes. 2022;71:2642-2655.
    PubMed     Abstract available


    November 2022
  58. GUO Z, Kasinathan D, Merriman C, Nakayama M, et al
    A Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for in vivo beta-Cell Imaging and Islet-Specific Therapies.
    Diabetes. 2022 Nov 30:db220477. doi: 10.2337/db22-0477.
    PubMed     Abstract available


  59. DERR AG, Arowosegbe A, Satish B, Redick SD, et al
    An Early Islet Transcriptional Signature is Associated with Local Inflammation in Autoimmune Diabetes.
    Diabetes. 2022 Nov 8. pii: 147854. doi: 10.2337/db22-0521.
    PubMed     Abstract available


  60. TANG X, Wang J, Abboud HE, Chen Y, et al
    Sustained Upregulation of Endothelial Nox4 Mediates Retinal Vascular Pathology in Type 1 Diabetes.
    Diabetes. 2022 Nov 2. pii: 147850. doi: 10.2337/db22-0194.
    PubMed     Abstract available


  61. NG XW, Chung YH, Asadi F, Kong C, et al
    RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic alpha-Cells.
    Diabetes. 2022;71:2384-2394.
    PubMed     Abstract available


    October 2022
  62. GUYER P, Arribas-Layton D, Manganaro A, Speake C, et al
    Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4+ T Cells in Type 1 Diabetes.
    Diabetes. 2022 Oct 6. pii: 147715. doi: 10.2337/db22-0191.
    PubMed     Abstract available


  63. CORKEY BE, Kilpatrick LE, Evans-Molina C
    Hypothesis: Induction of Autoimmunity in Type 1 Diabetes-A Lipid Focus.
    Diabetes. 2022;71:2067-2074.
    PubMed     Abstract available


    September 2022
  64. KWON BC, Achenbach P, Anand V, Frohnert BI, et al
    Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals with Presymptomatic Type 1 Diabetes.
    Diabetes. 2022 Sep 16. pii: 147551. doi: 10.2337/db22-0360.
    PubMed     Abstract available


  65. SHARMA A, Misra-Hebert AD, Mariam A, Milinovich A, et al
    Impacts of COVID-19 on Glycemia and Risk of Diabetic Ketoacidosis.
    Diabetes. 2022 Sep 15. pii: 147590. doi: 10.2337/db22-0264.
    PubMed     Abstract available


  66. SOOKAROMDEE P, Wiwanitkit V
    Comment on D'Addio et al. Immunogenicity and Safety of SARS-CoV-2 mRNA Vaccines in a Cohort of Patients With Type 1 Diabetes. Diabetes 2022;71:1800-1806.
    Diabetes. 2022;71:e13.
    PubMed    


  67. D'ADDIO F, Fiorina P
    Response to Comment on D'Addio et al. Immunogenicity and Safety of SARS-CoV-2 mRNA Vaccines in a Cohort of Patients With Type 1 Diabetes. Diabetes 2022;71:1800-1806.
    Diabetes. 2022;71:e14.
    PubMed    


    August 2022
  68. CRAWFORD SA, Wiles TA, Wenzlau JM, Powell RL, et al
    Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes.
    Diabetes. 2022 Aug 30. pii: 147526. doi: 10.2337/db22-0303.
    PubMed     Abstract available


  69. MALLONE R, Halliez C, Rui J, Herold KC, et al
    The beta-Cell in Type 1 Diabetes Pathogenesis: A Victim of Circumstances or an Instigator of Tragic Events?
    Diabetes. 2022;71:1603-1610.
    PubMed     Abstract available


    June 2022
  70. CORVILLO F, Abel BS, Lopez-Lera A, Ceccarini G, et al
    Characterization and Clinical Association of Autoantibodies Against Perilipin 1 in Patients with Acquired Generalized Lipodystrophy.
    Diabetes. 2022 Jun 30. pii: 147153. doi: 10.2337/db21-1086.
    PubMed     Abstract available


  71. CHEN M, Hu R, Cavinato C, Zhuang ZW, et al
    Fibronectin-integrin alpha5 signaling in vascular complications of type 1 diabetes.
    Diabetes. 2022 Jun 30. pii: 147154. doi: 10.2337/db21-0958.
    PubMed     Abstract available


  72. ITO Y, Sun R, Yagimuma H, Taki K, et al
    Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Insulin-Dependent Diabetes Mellitus Treated with Leptin.
    Diabetes. 2022 Jun 24. pii: 147141. doi: 10.2337/db21-0953.
    PubMed     Abstract available


  73. MEI-LING Y, Sean E C, Renelle G, TuKiet T L, et al
    Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity.
    Diabetes. 2022 Jun 22. pii: 147120. doi: 10.2337/db21-0989.
    PubMed     Abstract available


  74. CARRY PM, Waugh K, Vanderlinden LA, Johnson RK, et al
    Changes in the Co-Expression of Innate Immunity Genes During Persistent Islet Autoimmunity are Associated with Progression of Islet Autoimmunity: The Diabetes Autoimmunity Study in the Young (DAISY).
    Diabetes. 2022 Jun 20. pii: 147107. doi: 10.2337/db21-1111.
    PubMed     Abstract available


  75. LEUNG SS, Borg DJ, McCarthy DA, Boursalian TE, et al
    Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells.
    Diabetes. 2022 Jun 17. pii: 147090. doi: 10.2337/db22-0177.
    PubMed     Abstract available


  76. MACDONALD MJ, Ansari IH, Riedemann AS, Stoker SW, et al
    A Novel Intron-Encoded Neuropilin-1 Isoform in Pancreatic Islets Associated With Very Young Age of Onset of Type 1 Diabetes.
    Diabetes. 2022 Jun 17. pii: 147085. doi: 10.2337/db21-1070.
    PubMed     Abstract available


  77. MANDEL-BREHM C, Vazquez SE, Liverman C, Cheng M, et al
    Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy.
    Diabetes. 2022 Jun 16. pii: 147096. doi: 10.2337/db21-1172.
    PubMed     Abstract available


    May 2022
  78. LIN Y, Perovanovic J, Kong Y, Igyarto BZ, et al
    Antibody-Mediated Targeting of a Hybrid-Insulin-Peptide Towards Neonatal Thymic Langerin+ Cells Enhances T Cell Central Tolerance and Delays Autoimmune Diabetes.
    Diabetes. 2022 May 27. pii: 147050. doi: 10.2337/db21-1069.
    PubMed     Abstract available


  79. BAKER NL, Hammad SM, Hunt KJ, Semler A, et al
    Plasma ApoM levels and Progression to Kidney Dysfunction in Type 1 Diabetics.
    Diabetes. 2022 May 12. pii: 146945. doi: 10.2337/db21-0920.
    PubMed     Abstract available


  80. D'ADDIO F, Sabiu G, Usuelli V, Assi E, et al
    Immunogenicity and safety of SARS-CoV-2 mRNA vaccines in a cohort of patients with type 1 diabetes.
    Diabetes. 2022 May 12. pii: 146944. doi: 10.2337/db22-0053.
    PubMed     Abstract available


  81. CARR ALJ, Inshaw JRJ, Flaxman CS, Leete P, et al
    Circulating C-Peptide Levels in Living Children and Young People and Pancreatic Beta Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
    Diabetes. 2022 May 2. pii: 146866. doi: 10.2337/db22-0097.
    PubMed     Abstract available


  82. YIP L, Alkhataybeh R, Taylor C, Fuhlbrigge R, et al
    Identification of Novel Disease-Relevant Genes and Pathways in the Pathogenesis of Type 1 Diabetes: A Potential Defect in Pancreatic Iron Homeostasis.
    Diabetes. 2022 May 2. pii: 146861. doi: 10.2337/db21-0948.
    PubMed     Abstract available


  83. JING Y, Kong Y, McGinty J, Blahnik-Fagan G, et al
    T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope.
    Diabetes. 2022;71:1012-1022.
    PubMed     Abstract available


    April 2022
  84. SIMS EK, Besser REJ, Dayan C, Geno Rasmussen C, et al
    Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective.
    Diabetes. 2022;71:610-623.
    PubMed     Abstract available


    March 2022
  85. PIETROPAOLO M, Hotez P, Giannoukakis N
    Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS CoV-2-Infected Young Individuals: Is it Type 1 Diabetes?
    Diabetes. 2022 Mar 16. pii: 144830. doi: 10.2337/db21-0831.
    PubMed     Abstract available


  86. DI PAOLA R, Marucci A, Trischitta V
    The Need to Increase Clinical Skills and Change the Genetic Testing Strategy for Monogenic Diabetes.
    Diabetes. 2022;71:379-380.
    PubMed    


    January 2022
  87. LIU YF, Powrie J, Arif S, Yang JHM, et al
    Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple beta-Cell Peptides in Type 1 Diabetes.
    Diabetes. 2022 Jan 24. pii: 140961. doi: 10.2337/db21-0728.
    PubMed     Abstract available


  88. BROOKS-WORRELL B, Hampe CS, Hattery EG, Palomino B, et al
    Islet Autoimmunity is Highly Prevalent and Associated With Diminished beta-Cell Function in Patients With Type 2 Diabetes in the Grade Study.
    Diabetes. 2022 Jan 21. pii: 140947. doi: 10.2337/db21-0590.
    PubMed     Abstract available


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    PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic beta-Cells in Autoimmune Diabetes.
    Diabetes. 2022 Jan 14. pii: 139308. doi: 10.2337/db21-0443.
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    Endosomal Sequestration of TLR4 Antibody Induces Myeloid-Derived Suppressor Cells and Reverses Acute Type 1 Diabetes.
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    Methazolamide Attenuates the Development of Diabetic Cardiomyopathy by Promoting beta-Catenin Degradation in Type 1 Diabetic Mice.
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    Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the Non-Obese Diabetic (NOD) Mouse.
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    December 2021
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    SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants with Type 1 Diabetes.
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    PubMed     Abstract available


  95. PANZER JK, Caicedo A
    Targeting the Pancreatic alpha-Cell to Prevent Hypoglycemia in Type 1 Diabetes.
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    November 2021
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    Genetic Control of Splicing at SIRPG Modulates Risk of Type 1 Diabetes.
    Diabetes. 2021 Nov 19. pii: db21-0194. doi: 10.2337/db21-0194.
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  97. CHARLES MA, Leslie RD
    Diabetes: Concepts of beta-Cell Organ Dysfunction and Failure Would Lead to Earlier Diagnoses and Prevention.
    Diabetes. 2021;70:2444-2456.
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  98. SHARMA RB, Landa-Galvan HV, Alonso LC
    Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic beta-Cells.
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    October 2021
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    Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes.
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    Found in Translation: Novel Insights Into Type 1 Diabetes and beta-Cell Biology.
    Diabetes. 2021;70:2185-2186.
    PubMed    


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    Long RNA Sequencing and Ribosome Profiling of Inflamed beta-Cells Reveal an Extensive Translatome Landscape.
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    September 2021
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    CD8+ T cells variably recognize native versus citrullinated GRP78 epitopes in type 1 diabetes.
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    Syntaxin 4 enrichment in beta-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice.
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  104. SIMS EK, Cuthbertson D, Herold KC, Sosenko JM, et al
    The Deterrence of Rapid Metabolic Decline within 3 Months after Teplizumab Treatment in Individuals at High Risk for Type 1 Diabetes.
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  105. SRIVASTAVA N, Hu H, Vomund AN, Peterson OJ, et al
    Chromogranin A Deficiency Confers Protection from Autoimmune Diabetes Via Multiple Mechanisms.
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    August 2021
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    From Pancreatic beta-Cell Gene Networks to Novel Therapies for Type 1 Diabetes.
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    Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes.
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    Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes.
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    Pancreatic differentiation of stem cells reveals pathogenesis of a syndrome of Ketosis-Prone Diabetes.
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    July 2021
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    The low-expression variant of FABP4 is associated with cardiovascular disease in type 1 diabetes.
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    Profile of podocyte translatome during development of type 2 and type 1 diabetic nephropathy using podocyte-specific TRAP mRNA RNA-seq.
    Diabetes. 2021 Jul 7. pii: db21-0110. doi: 10.2337/db21-0110.
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    June 2021
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    Cardiac Tissue Factor Regulates Inflammation, Hypertrophy and Heart Failure in Mouse Model of Type 1 Diabetes.
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    May 2021
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    Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes.
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    PubMed    


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    April 2021
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    March 2021
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    T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early Diabetes.
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    February 2021
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    How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
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    January 2021
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    December 2020
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    Baseline Assessment of Circulating microRNAs Near Diagnosis of Type 1 Diabetes Predicts Future Stimulated Insulin Secretion.
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    November 2020
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    October 2020
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    PubMed     Abstract available


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