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Articles published in Diabetes

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    May 2020
  1. LU G, Rausell-Palamos F, Zhang J, Zheng Z, et al
    Dextran Sulfate Protects Pancreatic beta-Cells, Reduces Autoimmunity and Ameliorates Type 1 Diabetes.
    Diabetes. 2020 May 7. pii: db19-0725. doi: 10.2337/db19-0725.
    PubMed     Abstract available

    February 2020
  2. LI Q, Parikh H, Butterworth MD, Lernmark A, et al
    Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study.
    Diabetes. 2020 Feb 6. pii: db19-0756. doi: 10.2337/db19-0756.
    PubMed     Abstract available

    January 2020
  3. JORNS A J A, Wedekind D W D, Jahne J J J, Lenzen S L S, et al
    Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared to Type 1 Diabetes Mellitus.
    Diabetes. 2020 Jan 23. pii: db19-0865. doi: 10.2337/db19-0865.
    PubMed     Abstract available

  4. KNOOP J, Eugster A, Gavrisan A, Lickert R, et al
    Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4(+) T Cells in Offspring.
    Diabetes. 2020 Jan 2. pii: db19-0751. doi: 10.2337/db19-0751.
    PubMed     Abstract available

    November 2019
  5. CABELLO-KINDELAN C, Mackey S, Sands A, Rodriguez J, et al
    Immunomodulation Followed By Antigen-Specific Treg Infusion Controls Islet Autoimmunity.
    Diabetes. 2019 Nov 11. pii: db19-0061. doi: 10.2337/db19-0061.
    PubMed     Abstract available

    October 2019
  6. KUSMARTSEVA I, Beery M, Hiller H, Padilla M, et al
    Temporal Analysis of Amylase Expression in Control, Autoantibody Positive, and Type 1 Diabetes Pancreatic Tissues.
    Diabetes. 2019 Oct 9. pii: db19-0554. doi: 10.2337/db19-0554.
    PubMed     Abstract available

  7. KOSKINEN MK, Mikk ML, Laine AP, Lempainen J, et al
    Longitudinal Pattern of First-Phase Insulin Response Is Associated with Genetic Variants Outside the Class II HLA Region in Children with Multiple Autoantibodies.
    Diabetes. 2019 Oct 7. pii: db19-0329. doi: 10.2337/db19-0329.
    PubMed     Abstract available

  8. SHARMA S, Pettus J, Gottschalk M, Abe B, et al
    Single-Cell Analysis of CD4 T Cells in Type 1 Diabetes: From Mouse to Man, How to Perform Mechanistic Studies.
    Diabetes. 2019;68:1886-1891.
    PubMed     Abstract available

    September 2019
  9. FLORIJN BW, Duijs JMGJ, Levels JH, Dallinga-Thie GM, et al
    Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic miRNAs Between Extracellular Vesicles, HDL and Ago-2.
    Diabetes. 2019 Sep 10. pii: db18-1360. doi: 10.2337/db18-1360.
    PubMed     Abstract available

    August 2019
  10. VUORI N, Sandholm N, Kumar A, Hietala K, et al
    CACNB2 is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes.
    Diabetes. 2019 Aug 22. pii: db19-0130. doi: 10.2337/db19-0130.
    PubMed     Abstract available

  11. BADILLO FG, Tegou FZ, Abreu MM, Masina R, et al
    CCL21 Expression in beta-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice.
    Diabetes. 2019 Aug 1. pii: db19-0239. doi: 10.2337/db19-0239.
    PubMed     Abstract available

  12. UNANUE ER, Wan X
    The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity.
    Diabetes. 2019;68:1544-1551.
    PubMed     Abstract available

  13. In This Issue of Diabetes.
    Diabetes. 2019;68:1539-1540.

    July 2019
  14. MATHEW AV, Jaiswal M, Ang L, Michailidis G, et al
    Impaired Amino Acid and TCA Metabolism and Cardiovascular Autonomic Neuropathy Progression in Type 1 Diabetes.
    Diabetes. 2019 Jul 23. pii: db19-0145. doi: 10.2337/db19-0145.
    PubMed     Abstract available

  15. KALLIONPAA H, Somani J, Tuomela S, Ullah U, et al
    Early Detection of Peripheral Blood Cell Signature in Children Developing Beta-Cell Autoimmunity at a Young Age.
    Diabetes. 2019 Jul 16. pii: db19-0287. doi: 10.2337/db19-0287.
    PubMed     Abstract available

  16. SOFI MH, Johnson BM, Gudi RR, Jolly A, et al
    Polysaccharide A-Dependent Opposing Effects of Mucosal and Systemic Exposures to Human Gut Commensal Bacteroides Fragilis in Type 1 Diabetes.
    Diabetes. 2019 Jul 16. pii: db19-0211. doi: 10.2337/db19-0211.
    PubMed     Abstract available

  17. AHMED S, Cerosaletti K, James E, Long SA, et al
    Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
    Diabetes. 2019;68:1366-1379.
    PubMed     Abstract available

    June 2019
  18. LOPES-VIRELLA MF, Bebu I, Hunt KJ, Virella G, et al
    Immune Complexes and the Risk of CVD in Type 1 Diabetes.
    Diabetes. 2019 Jun 19. pii: db19-0358. doi: 10.2337/db19-0358.
    PubMed     Abstract available

  19. BAKER RL, Rihanek M, Hohenstein AC, Nakayama M, et al
    Hybrid Insulin Peptides are Autoantigens in Type 1 Diabetes.
    Diabetes. 2019 Jun 7. pii: db19-0128. doi: 10.2337/db19-0128.
    PubMed     Abstract available

  20. ACEVEDO-CALADO MJ, Pietropaolo SL, Morran MP, Schnell S, et al
    Autoantibodies Directed to a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes.
    Diabetes. 2019 Jun 5. pii: db18-1351. doi: 10.2337/db18-1351.
    PubMed     Abstract available

  21. In This Issue of Diabetes.
    Diabetes. 2019;68:1097-1098.

  22. HABIB T, Long SA, Samuels PL, Brahmandam A, et al
    Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.
    Diabetes. 2019;68:1240-1250.
    PubMed     Abstract available

    May 2019
  23. KAESTNER KH, Powers AC, Naji A, Atkinson MA, et al
    NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP).
    Diabetes. 2019 May 24. pii: db19-0058. doi: 10.2337/db19-0058.
    PubMed     Abstract available

  24. ZHAO LP, Papadopoulos GK, Kwok B, Xu B, et al
    Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes.
    Diabetes. 2019 May 24. pii: db19-0273. doi: 10.2337/db19-0273.
    PubMed     Abstract available

  25. PURCELL AW, Sechi S, DiLorenzo TP
    The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes.
    Diabetes. 2019;68:879-886.
    PubMed     Abstract available

    April 2019
  26. HALLER MJ, Long SA, Blanchfield JL, Schatz DA, et al
    Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data.
    Diabetes. 2019 Apr 9. pii: db19-0057. doi: 10.2337/db19-0057.
    PubMed     Abstract available

  27. JOHNSON MB, De Franco E, Atma W Greeley S, Letourneau LR, et al
    Trisomy 21 is a Cause of Permanent Neonatal Diabetes that is Autoimmune but not HLA Associated.
    Diabetes. 2019 Apr 8. pii: db19-0045. doi: 10.2337/db19-0045.
    PubMed     Abstract available

  28. AYDEMIR O, Noble JA, Bailey J, Lernmark A, et al
    Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes.
    Diabetes. 2019 Apr 8. pii: db18-1128. doi: 10.2337/db18-1128.
    PubMed     Abstract available

  29. WIEDE F, Brodnicki T, Goh PK, Leong YA, et al
    T Cell-Specific PTPN2-Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Co-Morbidities.
    Diabetes. 2019 Apr 1. pii: db18-1362. doi: 10.2337/db18-1362.
    PubMed     Abstract available

    March 2019
  30. ZOBEL EH, Hasbak P, Winther SA, Stevns C, et al
    Cardiac Autonomic Function is Associated With Myocardial Flow Reserve in Type 1 Diabetes.
    Diabetes. 2019 Mar 12. pii: db18-1313. doi: 10.2337/db18-1313.
    PubMed     Abstract available

  31. RUSSELL MA, Redick SD, Blodgett DM, Richardson SJ, et al
    HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of islet beta-Cells from Donors with Type 1 Diabetes.
    Diabetes. 2019 Mar 4. pii: db18-0686. doi: 10.2337/db18-0686.
    PubMed     Abstract available

    Targeting the Brain to Cure Type 2 Diabetes.
    Diabetes. 2019;68:476-478.

  33. In This Issue of Diabetes.
    Diabetes. 2019;68:469-470.

    February 2019
  34. FIDLER TP, Marti A, Gerth K, Middleton EA, et al
    Glucose Metabolism is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes Mellitus.
    Diabetes. 2019 Feb 14. pii: db18-0981. doi: 10.2337/db18-0981.
    PubMed     Abstract available

  35. FABBRI M, Frixou M, Degano M, Fousteri G, et al
    Type 1 Diabetes in STAT Protein Family Mutations: Regulating the Th17/Treg Equilibrium and Beyond.
    Diabetes. 2019;68:258-265.
    PubMed     Abstract available

    January 2019
  36. SYREENI A, Sandholm N, Cao J, Toppila I, et al
    Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes.
    Diabetes. 2019 Jan 23. pii: db18-0573. doi: 10.2337/db18-0573.
    PubMed     Abstract available

  37. HIPPICH M, Beyerlein A, Hagopian WA, Krischer JP, et al
    Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families.
    Diabetes. 2019 Jan 17. pii: db18-0882. doi: 10.2337/db18-0882.
    PubMed     Abstract available

  38. VAN LUMMEL M, Buis DTP, Ringeling C, de Ru AH, et al
    Epitope Stealing as Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.
    Diabetes. 2019 Jan 9. pii: db18-0501. doi: 10.2337/db18-0501.

  39. SELVARAJAH D, Wilkinson ID, Fang F, Sankar A, et al
    Structural and Functional Abnormalities of the Primary Somatosensory Cortex in Diabetic Peripheral Neuropathy: A Multimodal MRI Study.
    Diabetes. 2019 Jan 7. pii: db18-0509. doi: 10.2337/db18-0509.
    PubMed     Abstract available

  40. In This Issue of Diabetes.
    Diabetes. 2019;68:1-2.

  41. COURTY E, Besseiche A, Do TTH, Liboz A, et al
    Adaptive beta-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance.
    Diabetes. 2019;68:95-108.
    PubMed     Abstract available

  42. HWANG JJ, Jiang L, Sanchez Rangel E, Fan X, et al
    Glycemic Variability and Brain Glucose Levels in Type 1 Diabetes.
    Diabetes. 2019;68:163-171.
    PubMed     Abstract available

    December 2018
  43. LAM CJ, Chatterjee A, Shen E, Cox AR, et al
    Low Level Insulin Content Within Abundant Non-Beta Islet Endocrine Cells in Long-Standing Type 1 Diabetes.
    Diabetes. 2018 Dec 14. pii: db18-0305. doi: 10.2337/db18-0305.
    PubMed     Abstract available

  44. KAWABATA Y, Nishida N, Awata T, Kawasaki E, et al
    A genome-Wide Association Study Confirming a Strong Effect of HLA and Identifying Variants in CSAD/lnc-ITGB7-1 on Chromosome 12q13.13 Associated with Susceptibility to Fulminant Type 1 Diabetes.
    Diabetes. 2018 Dec 14. pii: db18-0314. doi: 10.2337/db18-0314.
    PubMed     Abstract available

    November 2018
  45. HUGHES FM JR, Hirshman NA, Inouye BM, Jin H, et al
    NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.
    Diabetes. 2018 Nov 13. pii: db18-0845. doi: 10.2337/db18-0845.
    PubMed     Abstract available

  46. MILLER RG, Costacou T, Orchard TJ
    Risk Factor Modeling for Cardiovascular Disease in Type I Diabetes in the Pittsburgh Epidemiology of Diabetes Complications (EDC) Study: A Comparison to the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complicati
    Diabetes. 2018 Nov 8. pii: db18-0515. doi: 10.2337/db18-0515.
    PubMed     Abstract available

  47. ONIONS K, Gamez M, Buckner NR, Baker SL, et al
    VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy.
    Diabetes. 2018 Nov 2. pii: db18-0045. doi: 10.2337/db18-0045.
    PubMed     Abstract available

  48. BUITINGA M, Callebaut A, Marques Camara Sodre F, Crevecoeur I, et al
    Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.
    Diabetes. 2018;67:2337-2348.
    PubMed     Abstract available

  49. WILSON CS, Chhabra P, Marshall AF, Morr CV, et al
    Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice.
    Diabetes. 2018;67:2349-2360.
    PubMed     Abstract available

  50. In This Issue of Diabetes.
    Diabetes. 2018;67:2127-2128.

    October 2018
  51. ENDESFELDER D, Castell WZ, Bonifacio E, Rewers M, et al
    Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children.
    Diabetes. 2018 Oct 10. pii: db18-0594. doi: 10.2337/db18-0594.
    PubMed     Abstract available

    September 2018
  52. TORELLA D, Iaconetti C, Tarallo R, Marino F, et al
    MicroRNA Regulation of the Hyper-Proliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes Mellitus.
    Diabetes. 2018 Sep 26. pii: db17-1434. doi: 10.2337/db17-1434.
    PubMed     Abstract available

    The Ascending GLP-1 Road From Clinical Safety to Reduction of Cardiovascular Complications.
    Diabetes. 2018;67:1710-1719.
    PubMed     Abstract available

  54. ACCILI D
    Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture.
    Diabetes. 2018;67:1701-1709.
    PubMed     Abstract available

  55. BAKER RL, Jamison BL, Wiles TA, Lindsay RS, et al
    CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse.
    Diabetes. 2018;67:1836-1846.
    PubMed     Abstract available

    August 2018
  56. HORWITZ E, Krogvold L, Zhitomirsky S, Swisa A, et al
    Beta Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes.
    Diabetes. 2018 Aug 27. pii: db17-1006. doi: 10.2337/db17-1006.
    PubMed     Abstract available

  57. SALAMI F, Lee HS, Freyhult E, Larsson HE, et al
    Reduction in White Blood Cell, Neutrophil and Red Blood Cell counts Related to Gender, HLA and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes.
    Diabetes. 2018 Aug 13. pii: db18-0355. doi: 10.2337/db18-0355.
    PubMed     Abstract available

  58. CARROLL KR, Elfers EE, Stevens JJ, McNally JP, et al
    Extending Remission and Reversing New Onset Type 1 Diabetes by Targeted Ablation of Autoreactive T Cells.
    Diabetes. 2018 Aug 13. pii: db18-0204. doi: 10.2337/db18-0204.
    PubMed     Abstract available

  59. CREUSOT RJ, Postigo-Fernandez J, Teteloshvili N
    Altered Function of Antigen-Presenting Cells in Type 1 Diabetes: A Challenge for Antigen-Specific Immunotherapy?
    Diabetes. 2018;67:1481-1494.
    PubMed     Abstract available

  60. SINGER RA, Sussel L
    Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization.
    Diabetes. 2018;67:1461-1470.
    PubMed     Abstract available

    July 2018
  61. TEZZA S, Ben Nasr M, D'Addio F, Vergani A, et al
    Islet-Derived eATP Fuels Autoreactive CD8(+) Cells and Facilitates the Onset of Type 1 Diabetes.
    Diabetes. 2018 Jul 31. pii: db17-1227. doi: 10.2337/db17-1227.
    PubMed     Abstract available

  62. BROM M, Joosten L, Frielink C, Peeters H, et al
    Validation of (111)In-Exendin SPECT for the Determination of the Beta Cell Mass in BioBreeding Diabetes Prone Rats.
    Diabetes. 2018 Jul 25. pii: db17-1312. doi: 10.2337/db17-1312.
    PubMed     Abstract available

  63. CARRERO JA, Benshoff ND, Nalley K, Unanue ER, et al
    Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice.
    Diabetes. 2018 Jul 3. pii: db18-0331. doi: 10.2337/db18-0331.
    PubMed     Abstract available

  64. SANDRINE L, Sophie G, Alexis G, Franck L, et al
    A Humanized Mouse Model to Study Type 1 Diabetes.
    Diabetes. 2018 Jul 2. pii: db18-0202. doi: 10.2337/db18-0202.
    PubMed     Abstract available

  65. MICHELS AW, Gottlieb PA
    Learning From Past Failures of Oral Insulin Trials.
    Diabetes. 2018;67:1211-1215.
    PubMed     Abstract available

    June 2018
  66. ANQUETIL F, Mondanelli G, Gonzalez N, Rodriguez Calvo T, et al
    Loss of IDO1 Expression From Human Pancreatic beta-Cells Precedes Their Destruction During the Development of Type 1 Diabetes.
    Diabetes. 2018 Jun 26. pii: db17-1281. doi: 10.2337/db17-1281.
    PubMed     Abstract available

  67. STAMATOULI AM, Quandt Z, Perdigoto AL, Clark PL, et al
    Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors.
    Diabetes. 2018 Jun 24. pii: dbi18-0002. doi: 10.2337/dbi18-0002.
    PubMed     Abstract available

  68. JAMES EA, Pietropaolo M, Mamula MJ
    Immune Recognition of beta-Cells: Neoepitopes as Key Players in the Loss of Tolerance.
    Diabetes. 2018;67:1035-1042.
    PubMed     Abstract available

  69. In This Issue of Diabetes.
    Diabetes. 2018;67:1033-1034.

  70. YIN GN, Jin HR, Choi MJ, Limanjaya A, et al
    Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway.
    Diabetes. 2018;67:1149-1161.
    PubMed     Abstract available

    May 2018
  71. GREENBAUM CJ, Speake C, Krischer J, Buckner J, et al
    Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
    Diabetes. 2018 May 16. pii: db18-0065. doi: 10.2337/db18-0065.
    PubMed     Abstract available

  72. COOPER ME, El-Osta A, Allen TJ, Watson AMD, et al
    Metabolic Karma-The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture.
    Diabetes. 2018;67:785-790.
    PubMed     Abstract available

  73. In This Issue of Diabetes.
    Diabetes. 2018;67:783-784.

    April 2018
  74. MARRE ML, McGinty JW, Chow IT, DeNicola ME, et al
    Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.
    Diabetes. 2018 Apr 13. pii: db17-1166. doi: 10.2337/db17-1166.
    PubMed     Abstract available

  75. SUN H, Lee P, Yan C, Gao N, et al
    Inhibition of Soluble Epoxide Hydrolase 2 Ameliorates Diabetic Keratopathy and Impaired Wound Healing in Mouse Corneas.
    Diabetes. 2018 Apr 3. pii: db17-1336. doi: 10.2337/db17-1336.
    PubMed     Abstract available

  76. LAM CJ, Cox AR, Jacobson DR, Rankin MM, et al
    Highly Proliferative alpha-Cell-Related Islet Endocrine Cells in Human Pancreata.
    Diabetes. 2018;67:674-686.
    PubMed     Abstract available

    March 2018
  77. EMBURY CM, Wiesman AI, Proskovec AL, Heinrichs-Graham E, et al
    Altered Brain Dynamics in Patients with Type 1 Diabetes During Working Memory Processing.
    Diabetes. 2018 Mar 12. pii: db17-1382. doi: 10.2337/db17-1382.
    PubMed     Abstract available

  78. VIGNALI D, Cantarelli E, Bordignon C, Canu A, et al
    Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients with Type 1 Diabetes.
    Diabetes. 2018 Mar 5. pii: db17-1390. doi: 10.2337/db17-1390.
    PubMed     Abstract available

    February 2018
  79. FU Z, Wang Z, Liu CH, Gong Y, et al
    Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice.
    Diabetes. 2018 Feb 27. pii: db17-0830. doi: 10.2337/db17-0830.
    PubMed     Abstract available

  80. RACINE JJ, Stewart I, Ratiu J, Christianson G, et al
    Improved Murine-MHC-Deficient HLA-Transgenic NOD-Mouse Models for Type 1 Diabetes Therapy Development.
    Diabetes. 2018 Feb 22. pii: db17-1467. doi: 10.2337/db17-1467.
    PubMed     Abstract available

  81. SATAKE E, Pezzolesi MG, Md Dom ZI, Smiles AM, et al
    Circulating miRNA Profiles Associated With Hyperglycemia in Patients With Type 1 Diabetes Mellitus.
    Diabetes. 2018 Feb 16. pii: db17-1207. doi: 10.2337/db17-1207.
    PubMed     Abstract available

  82. ERIKSSON O, Johnstrom P, Cselenyi Z, Jahan M, et al
    In Vivo Visualization of beta-Cells by Targeting of GPR44.
    Diabetes. 2018;67:182-192.
    PubMed     Abstract available

  83. KAARSHOLM NC, Lin S, Yan L, Kelly T, et al
    Engineering Glucose Responsiveness Into Insulin.
    Diabetes. 2018;67:299-308.
    PubMed     Abstract available

    January 2018
  84. SMITH MJ, Rihanek M, Wasserfall C, Mathews CE, et al
    Loss of B Cell Anergy in Type 1 Diabetes is Associated with High Risk HLA and non-HLA Disease Susceptibility Alleles.
    Diabetes. 2018 Jan 17. pii: db17-0937. doi: 10.2337/db17-0937.
    PubMed     Abstract available

  85. KRONENBERG-VERSTEEG D, Eichmann M, Russell MA, de Ru A, et al
    Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes.
    Diabetes. 2018 Jan 17. pii: db17-0021. doi: 10.2337/db17-0021.
    PubMed     Abstract available

  86. LI J, Huynh P, Dai A, Wu T, et al
    Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
    Diabetes. 2018 Jan 8. pii: db17-0134. doi: 10.2337/db17-0134.
    PubMed     Abstract available

  87. JOHNSON MB, De Franco E, Allen HL, Al Senani A, et al
    Erratum. Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes. Diabetes 2017;66:2316-2322.
    Diabetes. 2018 Jan 5. pii: db18-er03b. doi: 10.2337.

  88. KALYANARAMAN H, Schwaerzer G, Ramdani G, Castillo F, et al
    Potein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes.
    Diabetes. 2018 Jan 4. pii: db17-0965. doi: 10.2337/db17-0965.
    PubMed     Abstract available

    December 2017
    Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No.
    Diabetes. 2017;66:2937-2939.

    November 2017
  90. NAKAHARA Y, Ozaki K, Matsuura T
    Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents.
    Diabetes. 2017;66:2868-2874.
    PubMed     Abstract available

    October 2017
  91. ZHOU C, Routh VH
    Thioredoxin-1 Overexpression in the Ventromedial Nucleus of the Hypothalamus (VMH) Preserves the Counterregulatory Response to Hypoglycemia During Type 1 Diabetes Mellitus in Male Rats.
    Diabetes. 2017 Oct 27. pii: db170930. doi: 10.2337/db17-0930.
    PubMed     Abstract available

  92. GU J, Yan X, Dai X, Wang Y, et al
    Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts.
    Diabetes. 2017 Oct 27. pii: db170219. doi: 10.2337/db17-0219.
    PubMed     Abstract available

  93. MILLER WP, Yang C, Mihailescu ML, Moore JA, et al
    Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes.
    Diabetes. 2017 Oct 26. pii: db170728. doi: 10.2337/db17-0728.
    PubMed     Abstract available

  94. NORRIS JM, Lee HS, Frederiksen B, Erlund I, et al
    Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity.
    Diabetes. 2017 Oct 23. pii: db170802. doi: 10.2337/db17-0802.
    PubMed     Abstract available

    September 2017
  95. WIEGERS EC, Rooijackers HM, Tack CJ, Groenewoud HJMM, et al
    Effect of Exercise-Induced Lactate Elevation on Brain Lactate Levels During Hypoglycemia in Patients with Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
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    PubMed     Abstract available

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    Beta Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.
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  97. KRISCHER JP, Liu X, Lernmark A, Hagopian WA, et al
    The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report.
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  98. RODRIGUEZ-CALVO T, Atkinson M, von Herrath MG
    Response to Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of beta-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345.
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    Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of beta-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345.
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    August 2017
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    Increased Effector Memory Insulin-Specific CD4+T-cells Correlate with Insulin Autoantibodies in Recent-Onset Type 1 Diabetic Patients.
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  101. HERNANDEZ-PEREZ M, Chopra G, Fine J, Conteh AM, et al
    Inhibition of 12/15-Lipoxygenase Protects Against beta Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes.
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    SMAD3/Stat3 Signaling Mediates beta-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes.
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    Bait and Trap: Enriching Autoreactive T Cells With beta-Cell Antigen-Loading Biomaterial Scaffolds for Early Detection of Type 1 Diabetes.
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    July 2017
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    Granzyme A-deficiency breaks immune tolerance and promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.
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    Islet Encapsulation: Physiological Possibilities and Limitations.
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    Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade.
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    Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis.
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    June 2017
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    UBASH3A Mediates Risk for Type 1 Diabetes through Inhibition of T-Cell Receptor-Induced NF-kappaB Signaling.
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    Higher Plasma Methylglyoxal Levels are Associated with Incident Cardiovascular Disease in Individuals with Type 1 Diabetes: a 12-Year Follow-Up Study.
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  110. O'KELL AL, Wasserfall C, Catchpole B, Davison LJ, et al
    Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked?
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    May 2017
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    Topical Erythropoietin Treatment Accelerates the Healing of Cutaneous Burn Wounds in Diabetic Pigs Through an Aquaporin-3-Dependent Mechanism.
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    Radiomanganese PET Detects Changes in Functional beta-cell Mass in Mouse Models of Diabetes.
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    PubMed     Abstract available

  113. JOHNSON MB, De Franco E, Lango-Allen H, Al Senani A, et al
    Recessively Inherited Lrba Mutations Cause Autoimmunity Presenting as Neonatal Diabetes.
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    Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart.
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    Local Sphingosine Kinase 1 Activity Improves Islet Transplantation.
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    April 2017
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    Magnetic Resonance Neurography Visualizes Abnormalities in Sciatic and Tibial Nerves in Patients with Type 1 Diabetes and Neuropathy.
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    A Single Bout of High-Intensity Interval Training Reduces Awareness of Subsequent Hypoglycemia in Patients with Type 1 Diabetes.
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    Renal and Vascular Effects of Uric Acid Lowering in Normouricemic Patients with Uncomplicated Type 1 Diabetes.
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    In Vivo Enrichment of Diabetogenic T Cells.
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    Neu5Gc and alpha1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs.
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    Metabolite Profiling of LADA Challenges the View of a Metabolically Distinct Subtype.
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    March 2017
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    The Effect of Diabetes on Cortical Function in Stroke: Implications for Post-Stroke Plasticity.
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    February 2017
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    Co-transplantation of Mesenchymal Stem Cells with Neonatal Porcine Islets Improve Graft Function in Diabetic Mice.
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    Spinal Disinhibition in Experimental and Clinical Painful Diabetic Neuropathy.
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    Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?
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    January 2017
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    Pro-inflammatory Effects of Hypoglycemia in Humans with or without Diabetes.
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    December 2016
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    Interferon gamma Limits Diabetogenic CD8 T-Cell Effector Responses in Type-1 Diabetes.
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    November 2016
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    Glomerular Endothelial Mitochondrial Dysfunction is Essential and Characteristic of Diabetic Kidney Disease Susceptibility.
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    Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy.
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    Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease.
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    The Insulin-Like Growth Factor Axis: A New Player in Gestational Diabetes Mellitus?
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    October 2016
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    Compensatory Hyper-Connectivity in Developing Brains of Young Children with Type 1 Diabetes.
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    September 2016
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    Anti-Thymocyte Globulin + G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders with Established Type 1 Diabetes.
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    Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type I Diabetes.
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    August 2016
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    July 2016
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    June 2016
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    Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Mellitus is the Result of Altered Notch Signaling.
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    DYRK1A: A Promising Drug Target for Islet Transplant-Based Diabetes Therapies.
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    May 2016
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    April 2016
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    A New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes also Associated with Blood and Skin Glycated Proteins.
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    Mast Cells Regulate Wound Healing in Diabetes.
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    Discovery of a Genetic Metabolic Cause for Mauriac Syndrome in Type 1 Diabetes.
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    Type 1 Diabetes Genetic Risk Score: a novel tool to discriminate monogenic and type 1 diabetes.
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    IL-13 pathway alterations impair iNKT cell-mediated regulation of T effector cells in Type 1 Diabetes.
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    Comment on Yang et al. Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes. Diabetes 2015;64:3891-3902.
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