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Articles published in Diabetes

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Single Articles


    January 2021
  1. FIRDESSA-FITE R, Johnson SN, Leon MA, Khosravi-Maharlooei M, et al
    Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes.
    Diabetes. 2021 Jan 19. pii: db20-0845. doi: 10.2337/db20-0845.
    PubMed     Abstract available


  2. WILLIAMS MD, Bacher R, Perry DJ, Grace CR, et al
    Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis.
    Diabetes. 2021 Jan 8. pii: db20-0937. doi: 10.2337/db20-0937.
    PubMed     Abstract available


    December 2020
  3. BARRETT HL, Donaghue KC, Forbes JM
    Going in Early: Hypoxia as a Target for Kidney Disease Prevention in Diabetes?
    Diabetes. 2020;69:2578-2580.
    PubMed    


  4. AZOURY ME, Tarayrah M, Afonso G, Pais A, et al
    Peptides Derived From Insulin Granule Proteins Are Targeted by CD8(+) T Cells Across MHC Class I Restrictions in Humans and NOD Mice.
    Diabetes. 2020;69:2678-2690.
    PubMed     Abstract available


    November 2020
  5. ADVANI A
    Acute Kidney Injury: A Bona Fide Complication of Diabetes.
    Diabetes. 2020;69:2229-2237.
    PubMed     Abstract available


    October 2020
  6. LI Q, Liu X, Yang J, Erlund I, et al
    Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: the TEDDY Study.
    Diabetes. 2020 Oct 26. pii: db20-0696. doi: 10.2337/db20-0696.
    PubMed     Abstract available


    September 2020
  7. THIEM K, van Dierendonck XAMH, Janssen AWM, Boogaard JP, et al
    A High Glycemic Burden Relates to Functional and Metabolic Alterations of Human Monocytes in Patients with Type 1 Diabetes.
    Diabetes. 2020 Sep 25. pii: db20-0568. doi: 10.2337/db20-0568.
    PubMed     Abstract available


    August 2020
  8. ZHAO LP, Papadopoulos GK, Kwok WW, Moustakas AK, et al
    Next Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes.
    Diabetes. 2020 Aug 31. pii: db20-0374. doi: 10.2337/db20-0374.
    PubMed     Abstract available


  9. BUZZETTI R, Tuomi T, Mauricio D, Pietropaolo M, et al
    Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel.
    Diabetes. 2020 Aug 26. pii: dbi20-0017. doi: 10.2337/dbi20-0017.
    PubMed     Abstract available


  10. AHLQVIST E, Prasad RB, Groop L
    Subtypes of Type 2 Diabetes Determined From Clinical Parameters.
    Diabetes. 2020 Aug 25. pii: dbi20-0001. doi: 10.2337/dbi20-0001.
    PubMed     Abstract available


  11. FILIP P, Canna A, Moheet A, Bednarik P, et al
    Structural Alterations in Deep Brain Structures in Type 1 Diabetes.
    Diabetes. 2020 Aug 24. pii: db19-1100. doi: 10.2337/db19-1100.
    PubMed     Abstract available


  12. JAFFA MA, Bebu I, Luttrell D, Braffett BH, et al
    Longitudinal Plasma Kallikrein Levels and Their Association with the Risk of Cardiovascular Disease Outcomes in Type 1 Diabetes in DCCT/EDIC.
    Diabetes. 2020 Aug 21. pii: db20-0427. doi: 10.2337/db20-0427.
    PubMed     Abstract available


  13. BONE RN, Oyebamiji O, Talware S, Selvaraj S, et al
    A Computational Approach for Defining a Signature of beta-Cell Golgi Stress in Diabetes Mellitus.
    Diabetes. 2020 Aug 20. pii: db20-0636. doi: 10.2337/db20-0636.
    PubMed     Abstract available


    July 2020
  14. CUROVIC VR, Suvitaival T, Mattila I, Ahonen L, et al
    Circulating Metabolites and Lipids are Associated to Diabetic Retinopathy in Individuals With Type 1 Diabetes.
    Diabetes. 2020 Jul 31. pii: db20-0104. doi: 10.2337/db20-0104.
    PubMed     Abstract available


  15. VINOVSKIS C, Li LP, Prasad P, Tommerdahl K, et al
    Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes.
    Diabetes. 2020 Jul 31. pii: db20-0457. doi: 10.2337/db20-0457.
    PubMed     Abstract available


  16. KRAMER F, Martinson AM, Papayannopoulou T, Kanter JE, et al
    Myocardial Infarction Does not Accelerate Atherosclerosis in a Mouse Model of Type 1 Diabetes.
    Diabetes. 2020 Jul 21. pii: db20-0152. doi: 10.2337/db20-0152.
    PubMed     Abstract available


  17. JAMES EA, Mallone R, Kent SC, DiLorenzo TP, et al
    T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal.
    Diabetes. 2020;69:1311-1335.
    PubMed     Abstract available


  18. ARRIBAS-LAYTON D, Guyer P, Delong T, Dang M, et al
    Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01.
    Diabetes. 2020;69:1492-1502.
    PubMed     Abstract available


    June 2020
  19. BARRA JM, Kozlovskaya V, Kharlampieva E, Tse HM, et al
    Localized Immunosuppression with Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection.
    Diabetes. 2020 Jun 25. pii: db20-0248. doi: 10.2337/db20-0248.
    PubMed     Abstract available


    May 2020
  20. FOLAND-ROSS LC, Tong G, Mauras N, Cato A, et al
    Brain Function Differences in Children With Type 1 Diabetes: An fMRI Study of Working Memory.
    Diabetes. 2020 May 29. pii: db20-0123. doi: 10.2337/db20-0123.
    PubMed     Abstract available


  21. SIMMONS KM, Mitchell AM, Alkanani AA, McDaniel KA, et al
    Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02.
    Diabetes. 2020 May 21. pii: db20-0038. doi: 10.2337/db20-0038.
    PubMed     Abstract available


  22. SOSENKO JM, Skyler JS, Herold KC, Schatz DA, et al
    Slowed Metabolic Decline after One Year of Oral Insulin Treatment among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 and TrialNet Oral Insulin Prevention Trials.
    Diabetes. 2020 May 21. pii: db20-0166. doi: 10.2337/db20-0166.
    PubMed     Abstract available


  23. LU G, Rausell-Palamos F, Zhang J, Zheng Z, et al
    Dextran Sulfate Protects Pancreatic beta-Cells, Reduces Autoimmunity and Ameliorates Type 1 Diabetes.
    Diabetes. 2020 May 7. pii: db19-0725. doi: 10.2337/db19-0725.
    PubMed     Abstract available


  24. GREGORY JM, Cherrington AD, Moore DJ
    The Peripheral Peril: Injected Insulin Induces Insulin Insensitivity in Type 1 Diabetes.
    Diabetes. 2020;69:837-847.
    PubMed     Abstract available


    April 2020
  25. BOLO NR, Jacobson AM, Musen G, Keshavan MS, et al
    Acute Hyperglycemia Increases Brain Pregenual Anterior Cingulate Cortex Glutamate Concentrations in Type 1 Diabetes Mellitus.
    Diabetes. 2020 Apr 15. pii: db19-0936. doi: 10.2337/db19-0936.
    PubMed     Abstract available


  26. ZHAO LP, Papadopoulos GK, Kwok WW, Moustakas AK, et al
    Motifs of Three HLA-DQ Amino Acid Residues (alpha44, beta57, beta135) Capture Full Association with the Risk of Type 1 Diabetes in DQ2 and DQ8 Children.
    Diabetes. 2020 Apr 3. pii: db20-0075. doi: 10.2337/db20-0075.
    PubMed     Abstract available


    March 2020
  27. CARI L, Montanucci P, Basta G, Petrillo MG, et al
    Microencapsulated G3C hybridoma cell graft delays the onset of spontaneous diabetes in NOD mice by an expansion of Gitr(+) Treg cells.
    Diabetes. 2020 Mar 13. pii: db19-0087. doi: 10.2337/db19-0087.
    PubMed     Abstract available


  28. MILLER RG, Orchard TJ
    Understanding Metabolic Memory: A Tale of Two Studies.
    Diabetes. 2020;69:291-299.
    PubMed     Abstract available


  29. BETTINI M, Scavuzzo MA, Liu B, Kolawole E, et al
    A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells.
    Diabetes. 2020;69:392-400.
    PubMed     Abstract available


    February 2020
  30. KUCK JL, Bonhof GJ, Strom A, Zaharia OP, et al
    Impairment in Baroreflex Sensitivity in Recent-Onset Type 2 Diabetes Without Progression Over 5 Years.
    Diabetes. 2020 Feb 21. pii: db19-0990. doi: 10.2337/db19-0990.
    PubMed     Abstract available


  31. STANKUTE I, Verkauskiene R, Blouin JL, Klee P, et al
    Systematic Genetic Study of Diabetic Youth in a Single Country Reveals the Prevalence of Diabetes Subtypes, Novel Candidate Genes, and Response to Precision Therapy.
    Diabetes. 2020 Feb 21. pii: db19-0974. doi: 10.2337/db19-0974.
    PubMed     Abstract available


  32. BRAFFETT BH, Gubitosi-Klug RA, Albers JW, Feldman EL, et al
    Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study.
    Diabetes. 2020 Feb 12. pii: db19-1046. doi: 10.2337/db19-1046.
    PubMed     Abstract available


  33. LI Q, Parikh H, Butterworth MD, Lernmark A, et al
    Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study.
    Diabetes. 2020 Feb 6. pii: db19-0756. doi: 10.2337/db19-0756.
    PubMed     Abstract available


    January 2020
  34. FORGETTA V, Manousaki D, Istomine R, Ross S, et al
    Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes.
    Diabetes. 2020 Jan 31. pii: db19-0831. doi: 10.2337/db19-0831.
    PubMed     Abstract available


  35. MOCHIDA T, Ueno H, Yamazoe N, Hiyoshi H, et al
    Insulin-Deficient Diabetic Condition Upregulates Insulin Secreting Capacity of Human iPSC-Derived Pancreatic Endocrine Progenitor Cells After Implantation in Mice.
    Diabetes. 2020 Jan 31. pii: db19-0728. doi: 10.2337/db19-0728.
    PubMed     Abstract available


  36. JORNS A J A, Wedekind D W D, Jahne J J J, Lenzen S L S, et al
    Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared to Type 1 Diabetes Mellitus.
    Diabetes. 2020 Jan 23. pii: db19-0865. doi: 10.2337/db19-0865.
    PubMed     Abstract available


  37. KNOOP J, Eugster A, Gavrisan A, Lickert R, et al
    Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4(+) T Cells in Offspring.
    Diabetes. 2020 Jan 2. pii: db19-0751. doi: 10.2337/db19-0751.
    PubMed     Abstract available


    December 2019
  38. EID SA, El Massry M, Hichor M, Haddad M, et al
    Targeting the NADPH Oxidase-4 and Liver X Receptor Signaling Axis Preserve Schwann Cell Integrity in Diabetic Mice.
    Diabetes. 2019 Dec 27. pii: db19-0517. doi: 10.2337/db19-0517.
    PubMed     Abstract available


  39. SHAPIRO MR, Wasserfall CH, McGrail SM, Posgai AL, et al
    Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.
    Diabetes. 2019 Dec 11. pii: db19-0942. doi: 10.2337/db19-0942.
    PubMed     Abstract available


  40. LIU B, Hood JD, Kolawole EM, Woodruff DM, et al
    A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery.
    Diabetes. 2019 Dec 5. pii: db19-0399. doi: 10.2337/db19-0399.
    PubMed     Abstract available


    November 2019
  41. FROHNERT BI, Webb-Robertson BJ, Bramer LM, Reehl SM, et al
    Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources.
    Diabetes. 2019 Nov 18. pii: db18-1263. doi: 10.2337/db18-1263.
    PubMed     Abstract available


  42. CABELLO-KINDELAN C, Mackey S, Sands A, Rodriguez J, et al
    Immunomodulation Followed By Antigen-Specific Treg Infusion Controls Islet Autoimmunity.
    Diabetes. 2019 Nov 11. pii: db19-0061. doi: 10.2337/db19-0061.
    PubMed     Abstract available


    October 2019
  43. LI M, Wang S, Xu K, Chen Y, et al
    High prevalence of a monogenic cause in Han Chinese diagnosed with type 1 diabetes, partly driven by non-syndromic recessive WFS1 mutations.
    Diabetes. 2019 Oct 28. pii: db19-0510. doi: 10.2337/db19-0510.
    PubMed     Abstract available


  44. KUSMARTSEVA I, Beery M, Hiller H, Padilla M, et al
    Temporal Analysis of Amylase Expression in Control, Autoantibody Positive, and Type 1 Diabetes Pancreatic Tissues.
    Diabetes. 2019 Oct 9. pii: db19-0554. doi: 10.2337/db19-0554.
    PubMed     Abstract available


  45. KOSKINEN MK, Mikk ML, Laine AP, Lempainen J, et al
    Longitudinal Pattern of First-Phase Insulin Response Is Associated with Genetic Variants Outside the Class II HLA Region in Children with Multiple Autoantibodies.
    Diabetes. 2019 Oct 7. pii: db19-0329. doi: 10.2337/db19-0329.
    PubMed     Abstract available


  46. SHARMA S, Pettus J, Gottschalk M, Abe B, et al
    Single-Cell Analysis of CD4 T Cells in Type 1 Diabetes: From Mouse to Man, How to Perform Mechanistic Studies.
    Diabetes. 2019;68:1886-1891.
    PubMed     Abstract available


    September 2019
  47. FLORIJN BW, Duijs JMGJ, Levels JH, Dallinga-Thie GM, et al
    Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic miRNAs Between Extracellular Vesicles, HDL and Ago-2.
    Diabetes. 2019 Sep 10. pii: db18-1360. doi: 10.2337/db18-1360.
    PubMed     Abstract available


    August 2019
  48. VUORI N, Sandholm N, Kumar A, Hietala K, et al
    CACNB2 is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes.
    Diabetes. 2019 Aug 22. pii: db19-0130. doi: 10.2337/db19-0130.
    PubMed     Abstract available


  49. BADILLO FG, Tegou FZ, Abreu MM, Masina R, et al
    CCL21 Expression in beta-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice.
    Diabetes. 2019 Aug 1. pii: db19-0239. doi: 10.2337/db19-0239.
    PubMed     Abstract available


  50. UNANUE ER, Wan X
    The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity.
    Diabetes. 2019;68:1544-1551.
    PubMed     Abstract available



  51. In This Issue of Diabetes.
    Diabetes. 2019;68:1539-1540.
    PubMed    


    July 2019
  52. MATHEW AV, Jaiswal M, Ang L, Michailidis G, et al
    Impaired Amino Acid and TCA Metabolism and Cardiovascular Autonomic Neuropathy Progression in Type 1 Diabetes.
    Diabetes. 2019 Jul 23. pii: db19-0145. doi: 10.2337/db19-0145.
    PubMed     Abstract available


  53. KALLIONPAA H, Somani J, Tuomela S, Ullah U, et al
    Early Detection of Peripheral Blood Cell Signature in Children Developing Beta-Cell Autoimmunity at a Young Age.
    Diabetes. 2019 Jul 16. pii: db19-0287. doi: 10.2337/db19-0287.
    PubMed     Abstract available


  54. SOFI MH, Johnson BM, Gudi RR, Jolly A, et al
    Polysaccharide A-Dependent Opposing Effects of Mucosal and Systemic Exposures to Human Gut Commensal Bacteroides Fragilis in Type 1 Diabetes.
    Diabetes. 2019 Jul 16. pii: db19-0211. doi: 10.2337/db19-0211.
    PubMed     Abstract available


  55. AHMED S, Cerosaletti K, James E, Long SA, et al
    Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
    Diabetes. 2019;68:1366-1379.
    PubMed     Abstract available


    June 2019
  56. LOPES-VIRELLA MF, Bebu I, Hunt KJ, Virella G, et al
    Immune Complexes and the Risk of CVD in Type 1 Diabetes.
    Diabetes. 2019 Jun 19. pii: db19-0358. doi: 10.2337/db19-0358.
    PubMed     Abstract available


  57. BAKER RL, Rihanek M, Hohenstein AC, Nakayama M, et al
    Hybrid Insulin Peptides are Autoantigens in Type 1 Diabetes.
    Diabetes. 2019 Jun 7. pii: db19-0128. doi: 10.2337/db19-0128.
    PubMed     Abstract available


  58. ACEVEDO-CALADO MJ, Pietropaolo SL, Morran MP, Schnell S, et al
    Autoantibodies Directed to a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes.
    Diabetes. 2019 Jun 5. pii: db18-1351. doi: 10.2337/db18-1351.
    PubMed     Abstract available



  59. In This Issue of Diabetes.
    Diabetes. 2019;68:1097-1098.
    PubMed    


  60. HABIB T, Long SA, Samuels PL, Brahmandam A, et al
    Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.
    Diabetes. 2019;68:1240-1250.
    PubMed     Abstract available


    May 2019
  61. KAESTNER KH, Powers AC, Naji A, Atkinson MA, et al
    NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP).
    Diabetes. 2019 May 24. pii: db19-0058. doi: 10.2337/db19-0058.
    PubMed     Abstract available


  62. ZHAO LP, Papadopoulos GK, Kwok B, Xu B, et al
    Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes.
    Diabetes. 2019 May 24. pii: db19-0273. doi: 10.2337/db19-0273.
    PubMed     Abstract available


  63. PURCELL AW, Sechi S, DiLorenzo TP
    The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes.
    Diabetes. 2019;68:879-886.
    PubMed     Abstract available


    April 2019
  64. HALLER MJ, Long SA, Blanchfield JL, Schatz DA, et al
    Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data.
    Diabetes. 2019 Apr 9. pii: db19-0057. doi: 10.2337/db19-0057.
    PubMed     Abstract available


  65. JOHNSON MB, De Franco E, Atma W Greeley S, Letourneau LR, et al
    Trisomy 21 is a Cause of Permanent Neonatal Diabetes that is Autoimmune but not HLA Associated.
    Diabetes. 2019 Apr 8. pii: db19-0045. doi: 10.2337/db19-0045.
    PubMed     Abstract available


  66. AYDEMIR O, Noble JA, Bailey J, Lernmark A, et al
    Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes.
    Diabetes. 2019 Apr 8. pii: db18-1128. doi: 10.2337/db18-1128.
    PubMed     Abstract available


  67. WIEDE F, Brodnicki T, Goh PK, Leong YA, et al
    T Cell-Specific PTPN2-Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Co-Morbidities.
    Diabetes. 2019 Apr 1. pii: db18-1362. doi: 10.2337/db18-1362.
    PubMed     Abstract available


    March 2019
  68. ZOBEL EH, Hasbak P, Winther SA, Stevns C, et al
    Cardiac Autonomic Function is Associated With Myocardial Flow Reserve in Type 1 Diabetes.
    Diabetes. 2019 Mar 12. pii: db18-1313. doi: 10.2337/db18-1313.
    PubMed     Abstract available


  69. RUSSELL MA, Redick SD, Blodgett DM, Richardson SJ, et al
    HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of islet beta-Cells from Donors with Type 1 Diabetes.
    Diabetes. 2019 Mar 4. pii: db18-0686. doi: 10.2337/db18-0686.
    PubMed     Abstract available


  70. THORENS B
    Targeting the Brain to Cure Type 2 Diabetes.
    Diabetes. 2019;68:476-478.
    PubMed    



  71. In This Issue of Diabetes.
    Diabetes. 2019;68:469-470.
    PubMed    


    February 2019
  72. FIDLER TP, Marti A, Gerth K, Middleton EA, et al
    Glucose Metabolism is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes Mellitus.
    Diabetes. 2019 Feb 14. pii: db18-0981. doi: 10.2337/db18-0981.
    PubMed     Abstract available


  73. FABBRI M, Frixou M, Degano M, Fousteri G, et al
    Type 1 Diabetes in STAT Protein Family Mutations: Regulating the Th17/Treg Equilibrium and Beyond.
    Diabetes. 2019;68:258-265.
    PubMed     Abstract available


    January 2019
  74. SYREENI A, Sandholm N, Cao J, Toppila I, et al
    Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes.
    Diabetes. 2019 Jan 23. pii: db18-0573. doi: 10.2337/db18-0573.
    PubMed     Abstract available


  75. HIPPICH M, Beyerlein A, Hagopian WA, Krischer JP, et al
    Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families.
    Diabetes. 2019 Jan 17. pii: db18-0882. doi: 10.2337/db18-0882.
    PubMed     Abstract available


  76. VAN LUMMEL M, Buis DTP, Ringeling C, de Ru AH, et al
    Epitope Stealing as Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.
    Diabetes. 2019 Jan 9. pii: db18-0501. doi: 10.2337/db18-0501.
    PubMed    


  77. SELVARAJAH D, Wilkinson ID, Fang F, Sankar A, et al
    Structural and Functional Abnormalities of the Primary Somatosensory Cortex in Diabetic Peripheral Neuropathy: A Multimodal MRI Study.
    Diabetes. 2019 Jan 7. pii: db18-0509. doi: 10.2337/db18-0509.
    PubMed     Abstract available



  78. In This Issue of Diabetes.
    Diabetes. 2019;68:1-2.
    PubMed    


  79. COURTY E, Besseiche A, Do TTH, Liboz A, et al
    Adaptive beta-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance.
    Diabetes. 2019;68:95-108.
    PubMed     Abstract available


  80. HWANG JJ, Jiang L, Sanchez Rangel E, Fan X, et al
    Glycemic Variability and Brain Glucose Levels in Type 1 Diabetes.
    Diabetes. 2019;68:163-171.
    PubMed     Abstract available


    December 2018
  81. LAM CJ, Chatterjee A, Shen E, Cox AR, et al
    Low Level Insulin Content Within Abundant Non-Beta Islet Endocrine Cells in Long-Standing Type 1 Diabetes.
    Diabetes. 2018 Dec 14. pii: db18-0305. doi: 10.2337/db18-0305.
    PubMed     Abstract available


  82. KAWABATA Y, Nishida N, Awata T, Kawasaki E, et al
    A genome-Wide Association Study Confirming a Strong Effect of HLA and Identifying Variants in CSAD/lnc-ITGB7-1 on Chromosome 12q13.13 Associated with Susceptibility to Fulminant Type 1 Diabetes.
    Diabetes. 2018 Dec 14. pii: db18-0314. doi: 10.2337/db18-0314.
    PubMed     Abstract available


    November 2018
  83. HUGHES FM JR, Hirshman NA, Inouye BM, Jin H, et al
    NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.
    Diabetes. 2018 Nov 13. pii: db18-0845. doi: 10.2337/db18-0845.
    PubMed     Abstract available


  84. MILLER RG, Costacou T, Orchard TJ
    Risk Factor Modeling for Cardiovascular Disease in Type I Diabetes in the Pittsburgh Epidemiology of Diabetes Complications (EDC) Study: A Comparison to the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complicati
    Diabetes. 2018 Nov 8. pii: db18-0515. doi: 10.2337/db18-0515.
    PubMed     Abstract available


  85. ONIONS K, Gamez M, Buckner NR, Baker SL, et al
    VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy.
    Diabetes. 2018 Nov 2. pii: db18-0045. doi: 10.2337/db18-0045.
    PubMed     Abstract available


  86. BUITINGA M, Callebaut A, Marques Camara Sodre F, Crevecoeur I, et al
    Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.
    Diabetes. 2018;67:2337-2348.
    PubMed     Abstract available


  87. WILSON CS, Chhabra P, Marshall AF, Morr CV, et al
    Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice.
    Diabetes. 2018;67:2349-2360.
    PubMed     Abstract available



  88. In This Issue of Diabetes.
    Diabetes. 2018;67:2127-2128.
    PubMed    


    October 2018
  89. ENDESFELDER D, Castell WZ, Bonifacio E, Rewers M, et al
    Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children.
    Diabetes. 2018 Oct 10. pii: db18-0594. doi: 10.2337/db18-0594.
    PubMed     Abstract available


    September 2018
  90. TORELLA D, Iaconetti C, Tarallo R, Marino F, et al
    MicroRNA Regulation of the Hyper-Proliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes Mellitus.
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    PubMed     Abstract available


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    The Ascending GLP-1 Road From Clinical Safety to Reduction of Cardiovascular Complications.
    Diabetes. 2018;67:1710-1719.
    PubMed     Abstract available


  92. ACCILI D
    Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture.
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    PubMed     Abstract available


  93. BAKER RL, Jamison BL, Wiles TA, Lindsay RS, et al
    CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse.
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    August 2018
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    Beta Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes.
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  95. SALAMI F, Lee HS, Freyhult E, Larsson HE, et al
    Reduction in White Blood Cell, Neutrophil and Red Blood Cell counts Related to Gender, HLA and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes.
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    Extending Remission and Reversing New Onset Type 1 Diabetes by Targeted Ablation of Autoreactive T Cells.
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  97. CREUSOT RJ, Postigo-Fernandez J, Teteloshvili N
    Altered Function of Antigen-Presenting Cells in Type 1 Diabetes: A Challenge for Antigen-Specific Immunotherapy?
    Diabetes. 2018;67:1481-1494.
    PubMed     Abstract available


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    Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization.
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    July 2018
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    Islet-Derived eATP Fuels Autoreactive CD8(+) Cells and Facilitates the Onset of Type 1 Diabetes.
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    Validation of (111)In-Exendin SPECT for the Determination of the Beta Cell Mass in BioBreeding Diabetes Prone Rats.
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  101. CARRERO JA, Benshoff ND, Nalley K, Unanue ER, et al
    Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice.
    Diabetes. 2018 Jul 3. pii: db18-0331. doi: 10.2337/db18-0331.
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    A Humanized Mouse Model to Study Type 1 Diabetes.
    Diabetes. 2018 Jul 2. pii: db18-0202. doi: 10.2337/db18-0202.
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  103. MICHELS AW, Gottlieb PA
    Learning From Past Failures of Oral Insulin Trials.
    Diabetes. 2018;67:1211-1215.
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    June 2018
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    Loss of IDO1 Expression From Human Pancreatic beta-Cells Precedes Their Destruction During the Development of Type 1 Diabetes.
    Diabetes. 2018 Jun 26. pii: db17-1281. doi: 10.2337/db17-1281.
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    Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors.
    Diabetes. 2018 Jun 24. pii: dbi18-0002. doi: 10.2337/dbi18-0002.
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  106. JAMES EA, Pietropaolo M, Mamula MJ
    Immune Recognition of beta-Cells: Neoepitopes as Key Players in the Loss of Tolerance.
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  107. In This Issue of Diabetes.
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    PubMed    


  108. YIN GN, Jin HR, Choi MJ, Limanjaya A, et al
    Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway.
    Diabetes. 2018;67:1149-1161.
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    May 2018
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    Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
    Diabetes. 2018 May 16. pii: db18-0065. doi: 10.2337/db18-0065.
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  110. COOPER ME, El-Osta A, Allen TJ, Watson AMD, et al
    Metabolic Karma-The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture.
    Diabetes. 2018;67:785-790.
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  111. In This Issue of Diabetes.
    Diabetes. 2018;67:783-784.
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    April 2018
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    Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.
    Diabetes. 2018 Apr 13. pii: db17-1166. doi: 10.2337/db17-1166.
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  113. SUN H, Lee P, Yan C, Gao N, et al
    Inhibition of Soluble Epoxide Hydrolase 2 Ameliorates Diabetic Keratopathy and Impaired Wound Healing in Mouse Corneas.
    Diabetes. 2018 Apr 3. pii: db17-1336. doi: 10.2337/db17-1336.
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  114. LAM CJ, Cox AR, Jacobson DR, Rankin MM, et al
    Highly Proliferative alpha-Cell-Related Islet Endocrine Cells in Human Pancreata.
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    March 2018
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    Altered Brain Dynamics in Patients with Type 1 Diabetes During Working Memory Processing.
    Diabetes. 2018 Mar 12. pii: db17-1382. doi: 10.2337/db17-1382.
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  116. VIGNALI D, Cantarelli E, Bordignon C, Canu A, et al
    Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients with Type 1 Diabetes.
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    February 2018
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    Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice.
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  118. RACINE JJ, Stewart I, Ratiu J, Christianson G, et al
    Improved Murine-MHC-Deficient HLA-Transgenic NOD-Mouse Models for Type 1 Diabetes Therapy Development.
    Diabetes. 2018 Feb 22. pii: db17-1467. doi: 10.2337/db17-1467.
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  119. SATAKE E, Pezzolesi MG, Md Dom ZI, Smiles AM, et al
    Circulating miRNA Profiles Associated With Hyperglycemia in Patients With Type 1 Diabetes Mellitus.
    Diabetes. 2018 Feb 16. pii: db17-1207. doi: 10.2337/db17-1207.
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  120. ERIKSSON O, Johnstrom P, Cselenyi Z, Jahan M, et al
    In Vivo Visualization of beta-Cells by Targeting of GPR44.
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    Engineering Glucose Responsiveness Into Insulin.
    Diabetes. 2018;67:299-308.
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    January 2018
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    Loss of B Cell Anergy in Type 1 Diabetes is Associated with High Risk HLA and non-HLA Disease Susceptibility Alleles.
    Diabetes. 2018 Jan 17. pii: db17-0937. doi: 10.2337/db17-0937.
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  123. KRONENBERG-VERSTEEG D, Eichmann M, Russell MA, de Ru A, et al
    Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes.
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  124. LI J, Huynh P, Dai A, Wu T, et al
    Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
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  125. JOHNSON MB, De Franco E, Allen HL, Al Senani A, et al
    Erratum. Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes. Diabetes 2017;66:2316-2322.
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  126. KALYANARAMAN H, Schwaerzer G, Ramdani G, Castillo F, et al
    Potein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes.
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    December 2017
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    Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No.
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    November 2017
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    Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents.
    Diabetes. 2017;66:2868-2874.
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    October 2017
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    Thioredoxin-1 Overexpression in the Ventromedial Nucleus of the Hypothalamus (VMH) Preserves the Counterregulatory Response to Hypoglycemia During Type 1 Diabetes Mellitus in Male Rats.
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  130. GU J, Yan X, Dai X, Wang Y, et al
    Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts.
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  131. MILLER WP, Yang C, Mihailescu ML, Moore JA, et al
    Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes.
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  132. NORRIS JM, Lee HS, Frederiksen B, Erlund I, et al
    Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity.
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    September 2017
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    Effect of Exercise-Induced Lactate Elevation on Brain Lactate Levels During Hypoglycemia in Patients with Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
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    Beta Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.
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  135. KRISCHER JP, Liu X, Lernmark A, Hagopian WA, et al
    The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report.
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  136. RODRIGUEZ-CALVO T, Atkinson M, von Herrath MG
    Response to Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of beta-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345.
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    Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of beta-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345.
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    August 2017
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    Increased Effector Memory Insulin-Specific CD4+T-cells Correlate with Insulin Autoantibodies in Recent-Onset Type 1 Diabetic Patients.
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  139. HERNANDEZ-PEREZ M, Chopra G, Fine J, Conteh AM, et al
    Inhibition of 12/15-Lipoxygenase Protects Against beta Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes.
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  140. XIAO X, Fischbach S, Zhang T, Chen C, et al
    SMAD3/Stat3 Signaling Mediates beta-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes.
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  141. FAN Y
    Bait and Trap: Enriching Autoreactive T Cells With beta-Cell Antigen-Loading Biomaterial Scaffolds for Early Detection of Type 1 Diabetes.
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    July 2017
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    Granzyme A-deficiency breaks immune tolerance and promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.
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    Islet Encapsulation: Physiological Possibilities and Limitations.
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    Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade.
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    Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis.
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    June 2017
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    UBASH3A Mediates Risk for Type 1 Diabetes through Inhibition of T-Cell Receptor-Induced NF-kappaB Signaling.
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    Higher Plasma Methylglyoxal Levels are Associated with Incident Cardiovascular Disease in Individuals with Type 1 Diabetes: a 12-Year Follow-Up Study.
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  148. O'KELL AL, Wasserfall C, Catchpole B, Davison LJ, et al
    Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked?
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    May 2017
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    Topical Erythropoietin Treatment Accelerates the Healing of Cutaneous Burn Wounds in Diabetic Pigs Through an Aquaporin-3-Dependent Mechanism.
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  150. HERNANDEZ R, Graves SA, Gregg T, VanDeusen HR, et al
    Radiomanganese PET Detects Changes in Functional beta-cell Mass in Mouse Models of Diabetes.
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  151. JOHNSON MB, De Franco E, Lango-Allen H, Al Senani A, et al
    Recessively Inherited Lrba Mutations Cause Autoimmunity Presenting as Neonatal Diabetes.
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  152. TUNCAY E, Bitirim VC, Durak A, Carrat GRJ, et al
    Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart.
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    Local Sphingosine Kinase 1 Activity Improves Islet Transplantation.
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    April 2017
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    Magnetic Resonance Neurography Visualizes Abnormalities in Sciatic and Tibial Nerves in Patients with Type 1 Diabetes and Neuropathy.
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  155. ROOIJACKERS HM, Wiegers EC, van der Graaf M, Thijssen DH, et al
    A Single Bout of High-Intensity Interval Training Reduces Awareness of Subsequent Hypoglycemia in Patients with Type 1 Diabetes.
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    Renal and Vascular Effects of Uric Acid Lowering in Normouricemic Patients with Uncomplicated Type 1 Diabetes.
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  158. SALAMA A, Mosser M, Leveque X, Perota A, et al
    Neu5Gc and alpha1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs.
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    Metabolite Profiling of LADA Challenges the View of a Metabolically Distinct Subtype.
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    March 2017
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    The Effect of Diabetes on Cortical Function in Stroke: Implications for Post-Stroke Plasticity.
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    February 2017
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    Co-transplantation of Mesenchymal Stem Cells with Neonatal Porcine Islets Improve Graft Function in Diabetic Mice.
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    Spinal Disinhibition in Experimental and Clinical Painful Diabetic Neuropathy.
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    Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?
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    January 2017
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    December 2016
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    November 2016
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    July 2016
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    May 2016
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