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Articles published in J Immunol

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    September 2021
  1. MANDEL-BREHM C, Fichtner ML, Jiang R, Winton VJ, et al
    Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes.
    J Immunol. 2021 Sep 20. pii: jimmunol.2100225. doi: 10.4049/jimmunol.2100225.
    PubMed     Abstract available


  2. ZHOU M, Dascani P, Ding C, Kos JT, et al
    Integrin CD11b Negatively Regulates B Cell Receptor Signaling to Shape Humoral Response during Immunization and Autoimmunity.
    J Immunol. 2021 Sep 1. pii: jimmunol.2100070. doi: 10.4049/jimmunol.2100070.
    PubMed     Abstract available


    August 2021
  3. LEE DSW, Yam JY, Grasmuck C, Dasoveanu D, et al
    CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein-Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response.
    J Immunol. 2021 Aug 16. pii: jimmunol.2001413. doi: 10.4049/jimmunol.2001413.
    PubMed     Abstract available


  4. BOULET S, Odagiu L, Dong M, Lebel ME, et al
    NR4A3 Mediates Thymic Negative Selection.
    J Immunol. 2021;207:1055-1064.
    PubMed     Abstract available


  5. MANOHARAN I, Swafford D, Shanmugam A, Patel N, et al
    Activation of Transcription Factor 4 in Dendritic Cells Controls Th1/Th17 Responses and Autoimmune Neuroinflammation.
    J Immunol. 2021 Aug 4. pii: jimmunol.2100010. doi: 10.4049/jimmunol.2100010.
    PubMed     Abstract available


  6. PERRY DJ, Peters LD, Lakshmi PS, Zhang L, et al
    Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4(+) T Cell Activation.
    J Immunol. 2021;207:849-859.
    PubMed     Abstract available


    June 2021
  7. CHURCH ME, Ceja G, McGeehan M, Miller MC, et al
    Meningeal B Cell Clusters Correlate with Submeningeal Pathology in a Natural Model of Multiple Sclerosis.
    J Immunol. 2021 Jun 23. pii: jimmunol.2000514. doi: 10.4049/jimmunol.2000514.
    PubMed     Abstract available


  8. NEEDHAM EJ, Stoevesandt O, Thelin EP, Zetterberg H, et al
    Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury.
    J Immunol. 2021 Jun 18. pii: jimmunol.2001309. doi: 10.4049/jimmunol.2001309.
    PubMed     Abstract available


  9. ZHANG J, Bouch RJ, Blekhman MG, He Z, et al
    USP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity.
    J Immunol. 2021 Jun 16. pii: jimmunol.2100205. doi: 10.4049/jimmunol.2100205.
    PubMed     Abstract available


  10. KO MK, Shao H, Kaplan HJ, Sun D, et al
    Timing Effect of Adenosine-Directed Immunomodulation on Mouse Experimental Autoimmune Uveitis.
    J Immunol. 2021 Jun 14. pii: jimmunol.2100182. doi: 10.4049/jimmunol.2100182.
    PubMed     Abstract available


  11. XIE JH, Zhang Y, Loubeau M, Mangan P, et al
    Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.
    J Immunol. 2021 Jun 9. pii: jimmunol.2100078. doi: 10.4049/jimmunol.2100078.
    PubMed     Abstract available


  12. SONODA S, Murata S, Kato H, Zakaria F, et al
    Targeting of Deciduous Tooth Pulp Stem Cell-Derived Extracellular Vesicles on Telomerase-Mediated Stem Cell Niche and Immune Regulation in Systemic Lupus Erythematosus.
    J Immunol. 2021 Jun 2. pii: jimmunol.2001312. doi: 10.4049/jimmunol.2001312.
    PubMed     Abstract available


    May 2021
  13. SCHELL SL, Bricker KN, Fike AJ, Chodisetti SB, et al
    Context-Dependent miR-21 Regulation of TLR7-Mediated Autoimmune and Foreign Antigen-Driven Antibody-Forming Cell and Germinal Center Responses.
    J Immunol. 2021 May 26. pii: jimmunol.2001039. doi: 10.4049/jimmunol.2001039.
    PubMed     Abstract available


  14. CHALAN P, Thomas N, Caturegli P
    Th17 Cells Contribute to the Pathology of Autoimmune Hypophysitis.
    J Immunol. 2021 May 19. pii: jimmunol.2001073. doi: 10.4049/jimmunol.2001073.
    PubMed     Abstract available


  15. CAI H, Liu X, Zhang F, Han QY, et al
    G3BP1 Inhibition Alleviates Intracellular Nucleic Acid-Induced Autoimmune Responses.
    J Immunol. 2021;206:2453-2467.
    PubMed     Abstract available


  16. HE R, Wu S, Gao R, Chen J, et al
    Identification of a Long Noncoding RNA TRAF3IP2-AS1 as Key Regulator of IL-17 Signaling through the SRSF10-IRF1-Act1 Axis in Autoimmune Diseases.
    J Immunol. 2021;206:2353-2365.
    PubMed     Abstract available



  17. Top Reads.
    J Immunol. 2021;206:2249.
    PubMed    


  18. LI Q, Feng C, Li L, Xu G, et al
    Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation.
    J Immunol. 2021;206:2338-2352.
    PubMed     Abstract available


    April 2021
  19. INOUE M, Yamashita K, Tsuji Y, Miki M, et al
    Characterization of a TNFR2-Selective Agonistic TNF-alpha Mutant and Its Derivatives as an Optimal Regulatory T Cell Expander.
    J Immunol. 2021;206:1740-1751.
    PubMed     Abstract available


  20. PAN W, Nagpal K, Suarez-Fueyo A, Ferretti A, et al
    The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway.
    J Immunol. 2021;206:1719-1728.
    PubMed     Abstract available


  21. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
    J Immunol. 2021 Apr 12. pii: jimmunol.2000719. doi: 10.4049/jimmunol.2000719.
    PubMed     Abstract available


  22. JOHNSON BM, Uchimura T, Gallovic MD, Thamilarasan M, et al
    STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways.
    J Immunol. 2021 Apr 5. pii: jimmunol.2001317. doi: 10.4049/jimmunol.2001317.
    PubMed     Abstract available


  23. LANGRISH CL, Bradshaw JM, Francesco MR, Owens TD, et al
    Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.
    J Immunol. 2021;206:1454-1468.
    PubMed     Abstract available


  24. LIN X, Tawch S, Wong HT, Roy S, et al
    Nrf2 through Aryl Hydrocarbon Receptor Regulates IL-22 Response in CD4(+) T Cells.
    J Immunol. 2021;206:1540-1548.
    PubMed     Abstract available


  25. CHIKUMA S, Yamanaka S, Nakagawa S, Ueda MT, et al
    TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus.
    J Immunol. 2021;206:1528-1539.
    PubMed     Abstract available


    March 2021
  26. CHO T, Sato H, Wakamatsu A, Ohashi R, et al
    Mood Disorder in Systemic Lupus Erythematosus Induced by Antiribosomal P Protein Antibodies Associated with Decreased Serum and Brain Tryptophan.
    J Immunol. 2021 Mar 31. pii: jimmunol.2000260. doi: 10.4049/jimmunol.2000260.
    PubMed     Abstract available


  27. BEN NASR M, Usuelli V, Seelam AJ, D'Addio F, et al
    Regulatory B Cells in Autoimmune Diabetes.
    J Immunol. 2021;206:1117-1125.
    PubMed     Abstract available


  28. BRATE AA, Boyden AW, Jensen IJ, Badovinac VP, et al
    A Functionally Distinct CXCR3(+)/IFN-gamma(+)/IL-10(+) Subset Defines Disease-Suppressive Myelin-Specific CD8 T Cells.
    J Immunol. 2021;206:1151-1160.
    PubMed     Abstract available


  29. NANDEDKAR-KULKARNI N, Esakov E, Gregg B, Atkinson MA, et al
    Insulin Receptor-Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice.
    J Immunol. 2021 Mar 3. pii: jimmunol.1900357. doi: 10.4049/jimmunol.1900357.
    PubMed     Abstract available


  30. CHEN L, Bai J, Peng D, Gao Y, et al
    SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2alpha to Suppress Th17 Cell Differentiation.
    J Immunol. 2021;206:953-962.
    PubMed     Abstract available


  31. THOMSON AS, Mai SH, Bouma G, Herdman M, et al
    Structure and Functional Characterization of a Humanized Anti-CCL20 Antibody following Exposure to Serum Reveals the Formation of Immune Complex That Leads to Toxicity.
    J Immunol. 2021;206:1067-1076.
    PubMed     Abstract available


    February 2021
  32. SALINAS VH, Stuve O
    Systems Approaches to Unravel T Cell Function and Therapeutic Potential in Autoimmune Disease.
    J Immunol. 2021;206:669-675.
    PubMed     Abstract available


  33. CUNNINGHAM KT, Finlay CM, Mills KHG
    Helminth Imprinting of Hematopoietic Stem Cells Sustains Anti-Inflammatory Trained Innate Immunity That Attenuates Autoimmune Disease.
    J Immunol. 2021 Feb 12. pii: jimmunol.2001225. doi: 10.4049/jimmunol.2001225.
    PubMed     Abstract available


  34. ALLARD-CHAMARD H, Alsufyani F, Kaneko N, Xing K, et al
    CD4(+)CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum.
    J Immunol. 2021;206:524-530.
    PubMed     Abstract available


    January 2021
  35. HUARD A, Do HN, Frank AC, Sirait-Fischer E, et al
    IL-38 Ablation Reduces Local Inflammation and Disease Severity in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2021 Jan 27. pii: jimmunol.2000923. doi: 10.4049/jimmunol.2000923.
    PubMed     Abstract available


  36. BATES NA, Li A, Fan T, Cutcliffe MP, et al
    Gut Commensal Segmented Filamentous Bacteria Fine-Tune T Follicular Regulatory Cells to Modify the Severity of Systemic Autoimmune Arthritis.
    J Immunol. 2021 Jan 18. pii: jimmunol.2000663. doi: 10.4049/jimmunol.2000663.
    PubMed     Abstract available


  37. SIM JH, Ambler WG, Sollohub IF, Howlader MJ, et al
    Immune Cell-Stromal Circuitry in Lupus Photosensitivity.
    J Immunol. 2021;206:302-309.
    PubMed     Abstract available


  38. SUMIYOSHI M, Kotani Y, Ikuta Y, Suzue K, et al
    Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation.
    J Immunol. 2021;206:366-375.
    PubMed     Abstract available


  39. MOCKUS TE, Munie A, Atkinson JR, Segal BM, et al
    Encephalitogenic and Regulatory CD8 T Cells in Multiple Sclerosis and Its Animal Models.
    J Immunol. 2021;206:3-10.
    PubMed     Abstract available


    December 2020
  40. XU Z, Lin CC, Ho S, Vlad G, et al
    Suppression of Experimental Autoimmune Encephalomyelitis by ILT3.Fc.
    J Immunol. 2020 Dec 23. pii: jimmunol.2000265. doi: 10.4049/jimmunol.2000265.
    PubMed     Abstract available


  41. TURNIER JL, Kahlenberg JM
    The Role of Cutaneous Type I IFNs in Autoimmune and Autoinflammatory Diseases.
    J Immunol. 2020;205:2941-2950.
    PubMed     Abstract available


    November 2020
  42. BONAMI RH, Nyhoff LE, McNitt DH, Hulbert C, et al
    T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
    J Immunol. 2020 Nov 16. pii: jimmunol.1900464. doi: 10.4049/jimmunol.1900464.
    PubMed     Abstract available


  43. HAYES ET, Hagan CE, Khoryati L, Gavin MA, et al
    Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function.
    J Immunol. 2020;205:2667-2678.
    PubMed     Abstract available


  44. PINHEIRO DF, Szenes-Nagy AB, Maurano MM, Lietzenmayer M, et al
    Cutting Edge: Tissue Antigen Expression Levels Fine-Tune T Cell Differentiation Decisions In Vivo.
    J Immunol. 2020;205:2577-2582.
    PubMed     Abstract available


  45. SUNGNAK W, Wagner A, Kowalczyk MS, Bod L, et al
    T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity.
    J Immunol. 2020 Nov 9. pii: jimmunol.2000748. doi: 10.4049/jimmunol.2000748.
    PubMed     Abstract available


  46. VAN DER POEL M, Hoepel W, Hamann J, Huitinga I, et al
    IgG Immune Complexes Break Immune Tolerance of Human Microglia.
    J Immunol. 2020;205:2511-2518.
    PubMed     Abstract available


    October 2020
  47. RACINE JJ, Chapman HD, Doty R, Cairns BM, et al
    T Cells from NOD-PerIg Mice Target Both Pancreatic and Neuronal Tissue.
    J Immunol. 2020;205:2026-2038.
    PubMed     Abstract available


  48. TOSSBERG JT, Heinrich RM, Farley VM, Crooke PS 3rd, et al
    Adenosine-to-Inosine RNA Editing of Alu Double-Stranded (ds)RNAs Is Markedly Decreased in Multiple Sclerosis and Unedited Alu dsRNAs Are Potent Activators of Proinflammatory Transcriptional Responses.
    J Immunol. 2020 Oct 12. pii: jimmunol.2000384. doi: 10.4049/jimmunol.2000384.
    PubMed     Abstract available


    September 2020
  49. TAYLOR S, Whitfield M, Barratt J, Didangelos A, et al
    The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix.
    J Immunol. 2020 Sep 11. pii: jimmunol.2000448. doi: 10.4049/jimmunol.2000448.
    PubMed     Abstract available


  50. BARIK S, Cattin-Roy AN, Ukah TK, Miller MM, et al
    Type II Cytokines Fine-Tune Thymic T Cell Selection to Offset Murine Central Nervous System Autoimmunity.
    J Immunol. 2020 Sep 11. pii: jimmunol.2000614. doi: 10.4049/jimmunol.2000614.
    PubMed     Abstract available


  51. FREUDENHAMMER M, Voll RE, Binder SC, Keller B, et al
    Naive- and Memory-like CD21(low) B Cell Subsets Share Core Phenotypic and Signaling Characteristics in Systemic Autoimmune Disorders.
    J Immunol. 2020 Sep 9. pii: jimmunol.2000343. doi: 10.4049/jimmunol.2000343.
    PubMed     Abstract available


  52. DURIGUTTO P, Macor P, Pozzi N, Agostinis C, et al
    Complement Activation and Thrombin Generation by MBL Bound to beta2-Glycoprotein I.
    J Immunol. 2020;205:1385-1392.
    PubMed     Abstract available


    August 2020
  53. LI M, Yang C, Wang Y, Song W, et al
    The Expression of P2X7 Receptor on Th1, Th17, and Regulatory T Cells in Patients with Systemic Lupus Erythematosus or Rheumatoid Arthritis and Its Correlations with Active Disease.
    J Immunol. 2020 Aug 31. pii: jimmunol.2000222. doi: 10.4049/jimmunol.2000222.
    PubMed     Abstract available


  54. YE C, Low BE, Wiles MV, Brusko TM, et al
    CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice.
    J Immunol. 2020 Aug 31. pii: jimmunol.2000148. doi: 10.4049/jimmunol.2000148.
    PubMed     Abstract available


  55. ACHARYA M, Raso F, Sagadiev S, Gilbertson E, et al
    B Cell alphav Integrins Regulate TLR-Driven Autoimmunity.
    J Immunol. 2020 Aug 28. pii: jimmunol.1901056. doi: 10.4049/jimmunol.1901056.
    PubMed     Abstract available


  56. FINLAY CM, Cunningham KT, Doyle B, Mills KHG, et al
    IL-33-Stimulated Murine Mast Cells Polarize Alternatively Activated Macrophages, Which Suppress T Cells That Mediate Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2020 Aug 28. pii: jimmunol.1901321. doi: 10.4049/jimmunol.1901321.
    PubMed     Abstract available


  57. ZHANG X, Ciesielski M, Fenstermaker RA, Kaminski HJ, et al
    The Presence of Survivin on B Cells from Myasthenia Gravis Patients and the Potential of an Antibody to a Modified Survivin Peptide to Alleviate Weakness in an Animal Model.
    J Immunol. 2020 Aug 24. pii: jimmunol.2000482. doi: 10.4049/jimmunol.2000482.
    PubMed     Abstract available


    July 2020
  58. TUCKER CG, Mitchell JS, Martinov T, Burbach BJ, et al
    Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity.
    J Immunol. 2020 Jul 31. pii: jimmunol.2000007. doi: 10.4049/jimmunol.2000007.
    PubMed     Abstract available


  59. HONG H, Gao M, Wu Q, Yang P, et al
    IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice.
    J Immunol. 2020;205:346-358.
    PubMed     Abstract available


  60. CLARKE J, Yaqubi M, Futhey NC, Sedaghat S, et al
    Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells.
    J Immunol. 2020;205:398-406.
    PubMed     Abstract available


  61. RIJVERS L, Melief MJ, van Langelaar J, van der Vuurst de Vries RM, et al
    The Role of Autoimmunity-Related Gene CLEC16A in the B Cell Receptor-Mediated HLA Class II Pathway.
    J Immunol. 2020 Jul 8. pii: jimmunol.1901409. doi: 10.4049/jimmunol.1901409.
    PubMed     Abstract available


  62. STARK AK, Davenport ECM, Patton DT, Scudamore CL, et al
    Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation.
    J Immunol. 2020;205:78-89.
    PubMed     Abstract available


    June 2020
  63. LI Z, He C, Zhang J, Zhang H, et al
    P2Y6 Deficiency Enhances Dendritic Cell-Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2020 Jun 17. pii: jimmunol.1900916. doi: 10.4049/jimmunol.1900916.
    PubMed     Abstract available


  64. VANARSA K, Henderson J, Soomro S, Qin L, et al
    Upregulation of Proinflammatory Bradykinin Peptides in Systemic Lupus Erythematosus and Rheumatoid Arthritis.
    J Immunol. 2020 Jun 15. pii: jimmunol.1801167. doi: 10.4049/jimmunol.1801167.
    PubMed     Abstract available


  65. BOYDEN AW, Brate AA, Stephens LM, Karandikar NJ, et al
    Immune Autoregulatory CD8 T Cells Require IFN-gamma Responsiveness to Optimally Suppress Central Nervous System Autoimmunity.
    J Immunol. 2020 Jun 12. pii: jimmunol.2000211. doi: 10.4049/jimmunol.2000211.
    PubMed     Abstract available


  66. WU CY, Hua KF, Hsu WH, Suzuki Y, et al
    IgA Nephropathy Benefits from Compound K Treatment by Inhibiting NF-kappaB/NLRP3 Inflammasome and Enhancing Autophagy and SIRT1.
    J Immunol. 2020 Jun 1. pii: jimmunol.1900284. doi: 10.4049/jimmunol.1900284.
    PubMed     Abstract available


    May 2020
  67. QIU R, Yu X, Wang L, Han Z, et al
    Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity.
    J Immunol. 2020 May 15. pii: jimmunol.2000060. doi: 10.4049/jimmunol.2000060.
    PubMed     Abstract available


  68. BATRA L, Shrestha P, Zhao H, Woodward KB, et al
    Localized Immunomodulation with PD-L1 Results in Sustained Survival and Function of Allogeneic Islets without Chronic Immunosuppression.
    J Immunol. 2020;204:2840-2851.
    PubMed     Abstract available


  69. SKOPELJA-GARDNER S, Colonna L, Hermanson P, Sun X, et al
    Complement Deficiencies Result in Surrogate Pathways of Complement Activation in Novel Polygenic Lupus-like Models of Kidney Injury.
    J Immunol. 2020;204:2627-2640.
    PubMed     Abstract available


  70. EICHMANN M, Baptista R, Ellis RJ, Heck S, et al
    Costimulation Blockade Disrupts CD4(+) T Cell Memory Pathways and Uncouples Their Link to Decline in beta-Cell Function in Type 1 Diabetes.
    J Immunol. 2020 May 13. pii: jimmunol.1901439. doi: 10.4049/jimmunol.1901439.
    PubMed     Abstract available


    April 2020
  71. THAPA M, Tedesco D, Gumber S, Elrod EJ, et al
    Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease.
    J Immunol. 2020 Apr 24. pii: jimmunol.1900391. doi: 10.4049/jimmunol.1900391.
    PubMed     Abstract available


  72. FODA BM, Ciecko AE, Serreze DV, Ridgway WM, et al
    The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137(+) FOXP3(+) Regulatory CD4 T Cells.
    J Immunol. 2020 Apr 15. pii: jimmunol.1900485. doi: 10.4049/jimmunol.1900485.
    PubMed     Abstract available


  73. CHODISETTI SB, Fike AJ, Domeier PP, Schell SL, et al
    Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development.
    J Immunol. 2020 Apr 6. pii: jimmunol.2000170. doi: 10.4049/jimmunol.2000170.
    PubMed     Abstract available


    March 2020
  74. IHANTOLA EL, Ilmonen H, Kailaanmaki A, Rytkonen-Nissinen M, et al
    Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules.
    J Immunol. 2020 Mar 30. pii: jimmunol.1901079. doi: 10.4049/jimmunol.1901079.
    PubMed     Abstract available


  75. DENG Z, Law CS, Ho FO, Wang KM, et al
    A Defect in Thymic Tolerance Causes T Cell-Mediated Autoimmunity in a Murine Model of COPA Syndrome.
    J Immunol. 2020 Mar 20. pii: jimmunol.2000028. doi: 10.4049/jimmunol.2000028.
    PubMed     Abstract available


  76. HE X, Liu R, Fan T, Huang X, et al
    Treating Autoimmune Diseases by Targeting IL-23 with Gene-Silencing Pyrrole-Imidazole Polyamide.
    J Immunol. 2020 Mar 13. pii: jimmunol.1901215. doi: 10.4049/jimmunol.1901215.
    PubMed     Abstract available


  77. MATSUBARA H, Shimizu Y, Arai M, Yamagata A, et al
    PEPITEM/Cadherin 15 Axis Inhibits T Lymphocyte Infiltration and Glomerulonephritis in a Mouse Model of Systemic Lupus Erythematosus.
    J Immunol. 2020 Mar 13. pii: jimmunol.1900213. doi: 10.4049/jimmunol.1900213.
    PubMed     Abstract available


  78. CHEN J, Martindale JL, Abdelmohsen K, Kumar G, et al
    RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation.
    J Immunol. 2020 Mar 13. pii: jimmunol.1900769. doi: 10.4049/jimmunol.1900769.
    PubMed     Abstract available


    February 2020
  79. BERGOT AS, Buckle I, Cikaluru S, Naranjo JL, et al
    Regulatory T Cells Induced by Single-Peptide Liposome Immunotherapy Suppress Islet-Specific T Cell Responses to Multiple Antigens and Protect from Autoimmune Diabetes.
    J Immunol. 2020 Feb 28. pii: jimmunol.1901128. doi: 10.4049/jimmunol.1901128.
    PubMed     Abstract available


  80. LIU Z, Zhu L, Lu Z, Chen H, et al
    IL-37 Represses the Autoimmunity in Myasthenia Gravis via Directly Targeting Follicular Th and B Cells.
    J Immunol. 2020 Feb 28. pii: jimmunol.1901176. doi: 10.4049/jimmunol.1901176.
    PubMed     Abstract available


  81. FERNANDO R, Atkins SJ, Smith TJ
    Slit2 May Underlie Divergent Induction by Thyrotropin of IL-23 and IL-12 in Human Fibrocytes.
    J Immunol. 2020 Feb 21. pii: jimmunol.1900434. doi: 10.4049/jimmunol.1900434.
    PubMed     Abstract available


  82. WU CY, Hua KF, Chu CL, Yang SR, et al
    Tris DBA Ameliorates Accelerated and Severe Lupus Nephritis in Mice by Activating Regulatory T Cells and Autophagy and Inhibiting the NLRP3 Inflammasome.
    J Immunol. 2020 Feb 14. pii: jimmunol.1801610. doi: 10.4049/jimmunol.1801610.
    PubMed     Abstract available


  83. HUBER JE, Chang Y, Meinl I, Kumpfel T, et al
    Fingolimod Profoundly Reduces Frequencies and Alters Subset Composition of Circulating T Follicular Helper Cells in Multiple Sclerosis Patients.
    J Immunol. 2020 Feb 7. pii: jimmunol.1900955. doi: 10.4049/jimmunol.1900955.
    PubMed     Abstract available


    January 2020
  84. ZHU J, Hay AN, Potter AA, Richwine MW, et al
    Abrogated AID Function Prolongs Survival and Diminishes Renal Pathology in the BXSB Mouse Model of Systemic Lupus Erythematosus.
    J Immunol. 2020 Jan 27. pii: jimmunol.1900501. doi: 10.4049/jimmunol.1900501.
    PubMed     Abstract available


  85. CHEN HY, Wu YF, Chou FC, Wu YH, et al
    Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.
    J Immunol. 2020 Jan 22. pii: jimmunol.1901114. doi: 10.4049/jimmunol.1901114.
    PubMed     Abstract available


  86. KARPUS WJ
    Cytokines and Chemokines in the Pathogenesis of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2020;204:316-326.
    PubMed     Abstract available


  87. ANGIN M, Brignone C, Triebel F
    A LAG-3-Specific Agonist Antibody for the Treatment of T Cell-Induced Autoimmune Diseases.
    J Immunol. 2020 Jan 6. pii: jimmunol.1900823. doi: 10.4049/jimmunol.1900823.
    PubMed     Abstract available


  88. CHODISETTI SB, Fike AJ, Domeier PP, Singh H, et al
    Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity.
    J Immunol. 2020 Jan 3. pii: jimmunol.1901175. doi: 10.4049/jimmunol.1901175.
    PubMed     Abstract available


  89. MAHAJAN S, Mellins ED, Faccio R
    Diacylglycerol Kinase zeta Regulates Macrophage Responses in Juvenile Arthritis and Cytokine Storm Syndrome Mouse Models.
    J Immunol. 2020;204:137-146.
    PubMed     Abstract available


    December 2019
  90. WAN X, Pei W, Shahzad KA, Zhang L, et al
    Correction: A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide-Autoreactive CD4(+) and CD8(+) T Cells.
    J Immunol. 2019 Dec 23. pii: jimmunol.1901408. doi: 10.4049/jimmunol.1901408.
    PubMed    


  91. YOSHIMURA S, Thome R, Konno S, Mari ER, et al
    IL-9 Controls Central Nervous System Autoimmunity by Suppressing GM-CSF Production.
    J Immunol. 2019 Dec 18. pii: jimmunol.1801113. doi: 10.4049/jimmunol.1801113.
    PubMed     Abstract available


  92. SIMPSON SR, Rego SL, Harvey SE, Liu M, et al
    T Cells Produce IFN-alpha in the TREX1 D18N Model of Lupus-like Autoimmunity.
    J Immunol. 2019 Dec 11. pii: jimmunol.1900220. doi: 10.4049/jimmunol.1900220.
    PubMed     Abstract available


  93. TAHVILDARI M, Dana R
    Low-Dose IL-2 Therapy in Transplantation, Autoimmunity, and Inflammatory Diseases.
    J Immunol. 2019;203:2749-2755.
    PubMed     Abstract available


    November 2019
  94. ANDERSON W, Thorpe J, Long SA, Rawlings DJ, et al
    Efficient CRISPR/Cas9 Disruption of Autoimmune-Associated Genes Reveals Key Signaling Programs in Primary Human T Cells.
    J Immunol. 2019 Nov 13. pii: jimmunol.1900848. doi: 10.4049/jimmunol.1900848.
    PubMed     Abstract available


  95. BOVENSIEPEN CS, Schakat M, Sebode M, Zenouzi R, et al
    TNF-Producing Th1 Cells Are Selectively Expanded in Liver Infiltrates of Patients with Autoimmune Hepatitis.
    J Immunol. 2019 Nov 4. pii: jimmunol.1900124. doi: 10.4049/jimmunol.1900124.
    PubMed     Abstract available


    October 2019
  96. MARTIN K, Touil R, Kolb Y, Cvijetic G, et al
    Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity.
    J Immunol. 2019 Oct 28. pii: jimmunol.1900327. doi: 10.4049/jimmunol.1900327.
    PubMed     Abstract available


  97. ANDREAS N, Potthast M, Geiselhoringer AL, Garg G, et al
    RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells.
    J Immunol. 2019 Oct 2. pii: jimmunol.1801530. doi: 10.4049/jimmunol.1801530.
    PubMed     Abstract available


  98. DROHOMYRECKY PC, Doroshenko ER, Akkermann R, Moshkova M, et al
    Peroxisome Proliferator-Activated Receptor-delta Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2019 Oct 2. pii: jimmunol.1801200. doi: 10.4049/jimmunol.1801200.
    PubMed     Abstract available


    September 2019
  99. SHENG H, Marrero I, Maricic I, Fanchiang SS, et al
    Distinct PLZF(+)CD8alphaalpha(+) Unconventional T Cells Enriched in Liver Use a Cytotoxic Mechanism to Limit Autoimmunity.
    J Immunol. 2019 Sep 25. pii: jimmunol.1900832. doi: 10.4049/jimmunol.1900832.
    PubMed     Abstract available


  100. KAUSHANSKY N, Bakos E, Becker-Herman S, Shachar I, et al
    Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms.
    J Immunol. 2019 Sep 4. pii: jimmunol.1900424. doi: 10.4049/jimmunol.1900424.
    PubMed     Abstract available


    August 2019
  101. COLAMATTEO A, Maggioli E, Azevedo Loiola R, Hamid Sheikh M, et al
    Reduced Annexin A1 Expression Associates with Disease Severity and Inflammation in Multiple Sclerosis Patients.
    J Immunol. 2019 Aug 28. pii: jimmunol.1801683. doi: 10.4049/jimmunol.1801683.
    PubMed     Abstract available


  102. ENGLER JB, Heckmann NF, Jager J, Gold SM, et al
    Pregnancy Enables Expansion of Disease-Specific Regulatory T Cells in an Animal Model of Multiple Sclerosis.
    J Immunol. 2019 Aug 23. pii: jimmunol.1900611. doi: 10.4049/jimmunol.1900611.
    PubMed     Abstract available


  103. FRAUSSEN J, Marquez S, Takata K, Beckers L, et al
    Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD(-)CD27(-) Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients.
    J Immunol. 2019 Aug 7. pii: jimmunol.1801236. doi: 10.4049/jimmunol.1801236.
    PubMed     Abstract available


    July 2019
  104. ZHANG X, Kiapour N, Kapoor S, Khan T, et al
    IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2019 Jul 24. pii: jimmunol.1900311. doi: 10.4049/jimmunol.1900311.
    PubMed     Abstract available


  105. AKIYAMA C, Tsumiyama K, Uchimura C, Honda E, et al
    Conditional Upregulation of IFN-alpha Alone Is Sufficient to Induce Systemic Lupus Erythematosus.
    J Immunol. 2019 Jul 19. pii: jimmunol.1801617. doi: 10.4049/jimmunol.1801617.
    PubMed     Abstract available


  106. MARTINOV T, Swanson LA, Breed ER, Tucker CG, et al
    Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes.
    J Immunol. 2019 Jul 19. pii: jimmunol.1801535. doi: 10.4049/jimmunol.1801535.
    PubMed     Abstract available


  107. LIN Y, Cui C, Su M, Tian X, et al
    Skint8, a Novel B7 Family-Related Molecule, Negatively Regulates T Cell Responses.
    J Immunol. 2019;203:400-407.
    PubMed     Abstract available


  108. TITOV AA, Baker HV, Brusko TM, Sobel ES, et al
    Metformin Inhibits the Type 1 IFN Response in Human CD4(+) T Cells.
    J Immunol. 2019;203:338-348.
    PubMed     Abstract available


  109. LINDAHL H, Guerreiro-Cacais AO, Bedri SK, Linnerbauer M, et al
    IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.
    J Immunol. 2019 Jul 10. pii: jimmunol.1900400. doi: 10.4049/jimmunol.1900400.
    PubMed     Abstract available


    June 2019
  110. VASQUEZ M, Consuegra-Fernandez M, Aranda F, Jimenez A, et al
    Treatment of Experimental Autoimmune Encephalomyelitis by Sustained Delivery of Low-Dose IFN-alpha.
    J Immunol. 2019 Jun 17. pii: jimmunol.1801462. doi: 10.4049/jimmunol.1801462.
    PubMed     Abstract available


  111. GU BH, Sprouse ML, Madison MC, Hong MJ, et al
    A Novel Animal Model of Emphysema Induced by Anti-Elastin Autoimmunity.
    J Immunol. 2019 Jun 10. pii: jimmunol.1900113. doi: 10.4049/jimmunol.1900113.
    PubMed     Abstract available


    May 2019
  112. PIANCONE F, Saresella M, Marventano I, La Rosa F, et al
    A Deficit of CEACAM-1-Expressing T Lymphocytes Supports Inflammation in Primary Progressive Multiple Sclerosis.
    J Immunol. 2019 May 29. pii: jimmunol.1801625. doi: 10.4049/jimmunol.1801625.
    PubMed     Abstract available


  113. STOCKS BT, Wilson CS, Marshall AF, Hoopes EM, et al
    Regulation of Diabetogenic Immunity by IL15-Activated Regulatory CD8 T Cells in Type 1 Diabetes.
    J Immunol. 2019 May 24. pii: jimmunol.1800976. doi: 10.4049/jimmunol.1800976.
    PubMed     Abstract available


  114. PERPER SJ, Westmoreland SV, Karman J, Twomey R, et al
    Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus.
    J Immunol. 2019 May 20. pii: jimmunol.1900043. doi: 10.4049/jimmunol.1900043.
    PubMed     Abstract available


  115. JAMISON BL, Neef T, Goodspeed A, Bradley B, et al
    Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells.
    J Immunol. 2019 May 20. pii: jimmunol.1900127. doi: 10.4049/jimmunol.1900127.
    PubMed     Abstract available


  116. BUDZINSKI L, Schulz AR, Baumgart S, Burns T, et al
    Osmium-Labeled Microspheres for Bead-Based Assays in Mass Cytometry.
    J Immunol. 2019;202:3103-3112.
    PubMed     Abstract available


  117. FRANKS SE, Getahun A, Cambier JC
    A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation.
    J Immunol. 2019 May 10. pii: jimmunol.1801394. doi: 10.4049/jimmunol.1801394.
    PubMed     Abstract available


  118. CHU T, Ni M, Chen C, Akilesh S, et al
    Cutting Edge: BCAP Promotes Lupus-like Disease and TLR-Mediated Type I IFN Induction in Plasmacytoid Dendritic Cells.
    J Immunol. 2019;202:2529-2534.
    PubMed     Abstract available


    April 2019
  119. MATSUO T, Hashimoto M, Sakaguchi S, Sakaguchi N, et al
    Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation.
    J Immunol. 2019 Apr 24. pii: jimmunol.1801159. doi: 10.4049/jimmunol.1801159.
    PubMed     Abstract available


  120. KEGERREIS BJ, Catalina MD, Geraci NS, Bachali P, et al
    Genomic Identification of Low-Density Granulocytes and Analysis of Their Role in the Pathogenesis of Systemic Lupus Erythematosus.
    J Immunol. 2019 Apr 24. pii: jimmunol.1801512. doi: 10.4049/jimmunol.1801512.
    PubMed     Abstract available


  121. CURRAN CS, Sommers CL, Young HA, Bourcier K, et al
    Report on the 2018 Cancer, Autoimmunity, and Immunology Conference.
    J Immunol. 2019 Apr 15. pii: jimmunol.1900264. doi: 10.4049/jimmunol.1900264.
    PubMed     Abstract available


  122. HASELMAYER P, Camps M, Liu-Bujalski L, Nguyen N, et al
    Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models.
    J Immunol. 2019 Apr 15. pii: jimmunol.1800583. doi: 10.4049/jimmunol.1800583.
    PubMed     Abstract available


  123. BOXBERGER N, Hecker M, Zettl UK
    Dysregulation of Inflammasome Priming and Activation by MicroRNAs in Human Immune-Mediated Diseases.
    J Immunol. 2019;202:2177-2187.
    PubMed     Abstract available


  124. KOERS J, Derksen NIL, Ooijevaar-de Heer P, Nota B, et al
    Biased N-Glycosylation Site Distribution and Acquisition across the Antibody V Region during B Cell Maturation.
    J Immunol. 2019;202:2220-2228.
    PubMed     Abstract available


  125. MCLACHLAN SM, Aliesky HA, Rapoport B
    Nanoparticles Bearing TSH Receptor Protein and a Tolerogenic Molecule Do Not Induce Immune Tolerance but Exacerbate Thyroid Autoimmunity in hTSHR/NOD.H2(h4) Mice.
    J Immunol. 2019 Apr 3. pii: jimmunol.1900038. doi: 10.4049/jimmunol.1900038.
    PubMed     Abstract available


  126. BROWN MA, Su MA
    An Inconvenient Variable: Sex Hormones and Their Impact on T Cell Responses.
    J Immunol. 2019;202:1927-1933.
    PubMed     Abstract available


  127. AMROUCHE K, Pers JO, Jamin C
    Glatiramer Acetate Stimulates Regulatory B Cell Functions.
    J Immunol. 2019;202:1970-1980.
    PubMed     Abstract available


    March 2019
  128. HAO F, Tian M, Feng Y, Quan C, et al
    Correction: Abrogation of Lupus Nephritis in Somatic Hypermutation-Deficient B6.MRL-Fas(lpr)/J Mice.
    J Immunol. 2019 Mar 27. pii: jimmunol.1900198. doi: 10.4049/jimmunol.1900198.
    PubMed    


  129. MOUNTZ JD, Hsu HC, Ballesteros-Tato A
    Dysregulation of T Follicular Helper Cells in Lupus.
    J Immunol. 2019;202:1649-1658.
    PubMed     Abstract available


  130. RAHAMAN O, Bhattacharya R, Liu CSC, Raychaudhuri D, et al
    Cutting Edge: Dysregulated Endocannabinoid-Rheostat for Plasmacytoid Dendritic Cell Activation in a Systemic Lupus Endophenotype.
    J Immunol. 2019;202:1674-1679.
    PubMed     Abstract available


  131. STATHOPOULOS P, Chastre A, Waters P, Irani S, et al
    Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.
    J Immunol. 2019 Mar 1. pii: jimmunol.1801295. doi: 10.4049/jimmunol.1801295.
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  132. GLATIGNY S, Hollbacher B, Motley SJ, Tan C, et al
    Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
    J Immunol. 2019;202:1373-1382.
    PubMed     Abstract available


    February 2019
  133. REYNOLDS CJ, Chong DLW, Li Y, Black SL, et al
    Bioluminescent Reporting of In Vivo IFN-gamma Immune Responses during Infection and Autoimmunity.
    J Immunol. 2019 Feb 27. pii: jimmunol.1801453. doi: 10.4049/jimmunol.1801453.
    PubMed     Abstract available


  134. LI R, Rezk A, Ghadiri M, Luessi F, et al
    Correction: Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis.
    J Immunol. 2019 Feb 15. pii: jimmunol.1900114. doi: 10.4049/jimmunol.1900114.
    PubMed    


  135. KHADER SA, Thirunavukkarasu S
    The Tale of IL-12 and IL-23: A Paradigm Shift.
    J Immunol. 2019;202:629-630.
    PubMed    


  136. BONEGIO RG, Lin JD, Beaudette-Zlatanova B, York MR, et al
    Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcgammaRIIA-Dependent but TLR-Independent Response.
    J Immunol. 2019;202:675-683.
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  137. LOWNIK JC, Wimberly JL, Conrad DH, Martin RK, et al
    B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis.
    J Immunol. 2019;202:664-674.
    PubMed     Abstract available


  138. HE Z, Zhang J, Du Q, Xu J, et al
    SRC3 Is a Cofactor for RORgammat in Th17 Differentiation but Not Thymocyte Development.
    J Immunol. 2019;202:760-769.
    PubMed     Abstract available


    January 2019
  139. KIM D, Le HT, Nguyen QT, Kim S, et al
    Cutting Edge: IL-27 Attenuates Autoimmune Neuroinflammation via Regulatory T Cell/Lag3-Dependent but IL-10-Independent Mechanisms In Vivo.
    J Immunol. 2019 Jan 30. pii: jimmunol.1800898. doi: 10.4049/jimmunol.1800898.
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  140. OUYANG S, Zeng Q, Tang N, Guo H, et al
    Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.
    J Immunol. 2019 Jan 28. pii: jimmunol.1701204. doi: 10.4049/jimmunol.1701204.
    PubMed     Abstract available


  141. DI DALMAZI G, Chalan P, Caturegli P
    MYMD-1, a Novel Immunometabolic Regulator, Ameliorates Autoimmune Thyroiditis via Suppression of Th1 Responses and TNF-alpha Release.
    J Immunol. 2019 Jan 23. pii: jimmunol.1801238. doi: 10.4049/jimmunol.1801238.
    PubMed     Abstract available


  142. DORRIS ER, Tazzyman SJ, Moylett J, Ramamoorthi N, et al
    The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation.
    J Immunol. 2019 Jan 18. pii: jimmunol.1801155. doi: 10.4049/jimmunol.1801155.
    PubMed     Abstract available


  143. QUAGLIA S, Ferrara F, De Leo L, Ziberna F, et al
    A Functional Idiotype/Anti-Idiotype Network Is Active in Genetically Gluten-Intolerant Individuals Negative for Both Celiac Disease-Related Intestinal Damage and Serum Autoantibodies.
    J Immunol. 2019 Jan 11. pii: jimmunol.1800819. doi: 10.4049/jimmunol.1800819.
    PubMed     Abstract available


  144. NIKITIN PA, Rose EL, Byun TS, Parry GC, et al
    C1s Inhibition by BIVV009 (Sutimlimab) Prevents Complement-Enhanced Activation of Autoimmune Human B Cells In Vitro.
    J Immunol. 2019 Jan 11. pii: jimmunol.1800998. doi: 10.4049/jimmunol.1800998.
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  145. NIKOOPOUR E, Lin CM, Sheskey S, Heckenlively JR, et al
    Immune Cell Infiltration into the Eye Is Controlled by IL-10 in Recoverin-Induced Autoimmune Retinopathy.
    J Immunol. 2019 Jan 11. pii: jimmunol.1800574. doi: 10.4049/jimmunol.1800574.
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  146. SKON-HEGG C, Zhang J, Wu X, Sagolla M, et al
    LACC1 Regulates TNF and IL-17 in Mouse Models of Arthritis and Inflammation.
    J Immunol. 2019;202:183-193.
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    December 2018
  147. ARMBRUST T, Millis MP, Alvarez ML, Saremi A, et al
    CXCL4L1 Promoter Polymorphisms Are Associated with Improved Renal Function in Type 1 Diabetes.
    J Immunol. 2018 Dec 28. pii: jimmunol.1801086. doi: 10.4049/jimmunol.1801086.
    PubMed     Abstract available


  148. CAI Y, Yang C, Yu X, Qian J, et al
    Deficiency of beta-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.
    J Immunol. 2018 Dec 12. pii: jimmunol.1800261. doi: 10.4049/jimmunol.1800261.
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  149. CLANCY RM, Halushka M, Rasmussen SE, Lhakhang T, et al
    Siglec-1 Macrophages and the Contribution of IFN to the Development of Autoimmune Congenital Heart Block.
    J Immunol. 2018 Dec 5. pii: jimmunol.1800357. doi: 10.4049/jimmunol.1800357.
    PubMed     Abstract available


  150. BISWAS PS
    IL-17 in Renal Immunity and Autoimmunity.
    J Immunol. 2018;201:3153-3159.
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    November 2018
  151. JAMES EA, Gillette L, Durinovic-Bello I, Speake C, et al
    DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.
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    PubMed     Abstract available


    October 2018
  152. HABIBULLAH M, Porter JA, Kluger N, Ranki A, et al
    Calcium-Sensing Receptor Autoantibodies in Patients with Autoimmune Polyendocrine Syndrome Type 1: Epitopes, Specificity, Functional Affinity, IgG Subclass, and Effects on Receptor Activity.
    J Immunol. 2018 Oct 31. pii: jimmunol.1701527. doi: 10.4049/jimmunol.1701527.
    PubMed     Abstract available


  153. DU SW, Jacobs HM, Arkatkar T, Rawlings DJ, et al
    Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells.
    J Immunol. 2018 Oct 29. pii: jimmunol.1800393. doi: 10.4049/jimmunol.1800393.
    PubMed     Abstract available


  154. LIN Q, Ohtsuji M, Amano H, Tsurui H, et al
    FcgammaRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus-Prone Yaa Mice.
    J Immunol. 2018 Oct 29. pii: jimmunol.1701487. doi: 10.4049/jimmunol.1701487.
    PubMed     Abstract available


  155. GARNIER L, Laffont S, Lelu K, Yogev N, et al
    Estrogen Signaling in Bystander Foxp3(neg) CD4(+) T Cells Suppresses Cognate Th17 Differentiation in Trans and Protects from Central Nervous System Autoimmunity.
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    PubMed     Abstract available


  156. KAP YS, Bus-Spoor C, van Driel N, Dubbelaar ML, et al
    Targeted Diet Modification Reduces Multiple Sclerosis-like Disease in Adult Marmoset Monkeys from an Outbred Colony.
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    PubMed     Abstract available


    September 2018
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    WDFY4 Involved in Symptoms of Systemic Lupus Erythematosus by Modulating B Cell Fate via Noncanonical Autophagy.
    J Immunol. 2018 Sep 26. pii: jimmunol.1800399. doi: 10.4049/jimmunol.1800399.
    PubMed     Abstract available


  158. HAMILTON JA, Wu Q, Yang P, Luo B, et al
    Cutting Edge: Intracellular IFN-beta and Distinct Type I IFN Expression Patterns in Circulating Systemic Lupus Erythematosus B Cells.
    J Immunol. 2018 Sep 10. pii: jimmunol.1800791. doi: 10.4049/jimmunol.1800791.
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    August 2018
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    Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis.
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  160. PRESA M, Racine JJ, Dwyer JR, Lamont DJ, et al
    A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8(+) T Cells in NOD Mice.
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    PubMed     Abstract available


  161. SPANGLER JB, Trotta E, Tomala J, Peck A, et al
    Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy.
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    July 2018
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    Effector T Cell Resistance to Suppression and STAT3 Signaling during the Development of Human Type 1 Diabetes.
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  163. WAN X, Pei W, Shahzad KA, Zhang L, et al
    A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide-Autoreactive CD4(+) and CD8(+) T Cells.
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  164. GALICIA G, Lee DSW, Ramaglia V, Ward LA, et al
    Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda(-/-) and Ung(-/-) Mice.
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    June 2018
  165. OSSART J, Moreau A, Autrusseau E, Menoret S, et al
    Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy-Candiasis-Ectodermal Dystrophy-like Autoimmune Disease.
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    Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes.
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  167. KATSUYAMA E, Yan M, Watanabe KS, Narazaki M, et al
    Correction: Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells.
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    PubMed    


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    TAPP Adaptors Control B Cell Metabolism by Modulating the Phosphatidylinositol 3-Kinase Signaling Pathway: A Novel Regulatory Circuit Preventing Autoimmunity.
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    PubMed     Abstract available


  169. WOLF SJ, Theros J, Reed TJ, Liu J, et al
    TLR7-Mediated Lupus Nephritis Is Independent of Type I IFN Signaling.
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    PubMed     Abstract available


  170. MONTEITH AJ, Vincent HA, Kang S, Li P, et al
    mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a.
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  171. SATO K, Honda SI, Shibuya A, Shibuya K, et al
    Cutting Edge: Identification of Marginal Reticular Cells as Phagocytes of Apoptotic B Cells in Germinal Centers.
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  174. FERNANDO R, Grisolia ABD, Lu Y, Atkins S, et al
    Slit2 Modulates the Inflammatory Phenotype of Orbit-Infiltrating Fibrocytes in Graves' Disease.
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  175. VALENTINE KM, Davini D, Lawrence TJ, Mullins GN, et al
    CD8 Follicular T Cells Promote B Cell Antibody Class Switch in Autoimmune Disease.
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  176. HAO F, Tian M, Feng Y, Quan C, et al
    Abrogation of Lupus Nephritis in Somatic Hypermutation-Deficient MRL/lpr Mice.
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  177. CHOI SC, Xu Z, Li W, Yang H, et al
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    Vasoactive Intestinal Peptide Ameliorates Acute Myocarditis and Atherosclerosis by Regulating Inflammatory and Autoimmune Responses.
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  179. SCHLOSS J, Ali R, Racine JJ, Chapman HD, et al
    HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.
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  180. NYHOFF LE, Clark ES, Barron BL, Bonami RH, et al
    Bruton's Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages.
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    Downregulation of CD3zeta in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype.
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  182. BELIKAN P, Buhler U, Wolf C, Pramanik GK, et al
    CCR7 on CD4(+) T Cells Plays a Crucial Role in the Induction of Experimental Autoimmune Encephalomyelitis.
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  183. JOAO C, Negi VS, Kazatchkine MD, Bayry J, et al
    Passive Serum Therapy to Immunomodulation by IVIG: A Fascinating Journey of Antibodies.
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  186. O'DONNELL JA, Lehman J, Roderick JE, Martinez-Marin D, et al
    Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
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    PubMed    


  187. SAGE PT, Schildberg FA, Sobel RA, Kuchroo VK, et al
    Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function.
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  188. DIXON KO, Schorer M, Nevin J, Etminan Y, et al
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    February 2018
  189. ZHANG R, Sage PT, Finn K, Huynh A, et al
    Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.
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    PubMed    


  190. SAPIR Y, Vitenshtein A, Barsheshet Y, Zohar Y, et al
    Correction: A Fusion Protein Encoding the Second Extracellular Domain of CCR5 Arrests Chemokine-Induced Cosignaling and Effectively Suppresses Ongoing Experimental Autoimmune Encephalomyelitis.
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    PubMed    


    January 2018
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    IL-10 Paradoxically Promotes Autoimmune Neuropathy through S1PR1-Dependent CD4(+) T Cell Migration.
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    PubMed     Abstract available



  192. Correction: NFAT1 Regulates Systemic Autoimmunity through the Modulation of a Dendritic Cell Property.
    J Immunol. 2018;200:880.
    PubMed    


  193. CORRADETTI C, Jog NR, Cesaroni M, Madaio M, et al
    Estrogen Receptor alpha Signaling Exacerbates Immune-Mediated Nephropathies through Alteration of Metabolic Activity.
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  194. ISEKA FM, Goetz BT, Mushtaq I, An W, et al
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  195. GUPTA S, Chan DW, Zaal KJ, Kaplan MJ, et al
    A High-Throughput Real-Time Imaging Technique To Quantify NETosis and Distinguish Mechanisms of Cell Death in Human Neutrophils.
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  196. YANG C, Lai W, Zhou J, Zheng X, et al
    Betaine Ameliorates Experimental Autoimmune Encephalomyelitis by Inhibiting Dendritic Cell-Derived IL-6 Production and Th17 Differentiation.
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  197. BURRACK AL, Landry LG, Siebert J, Coulombe M, et al
    Simultaneous Recognition of Allogeneic MHC and Cognate Autoantigen by Autoreactive T Cells in Transplant Rejection.
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  198. JEONG HJ, Lee HJ, Ko JH, Cho BJ, et al
    Myeloid-Derived Suppressor Cells Mediate Inflammation Resolution in Humans and Mice with Autoimmune Uveoretinitis.
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  199. WILLING A, Jager J, Reinhardt S, Kursawe N, et al
    Production of IL-17 by MAIT Cells Is Increased in Multiple Sclerosis and Is Associated with IL-7 Receptor Expression.
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  200. MAJRI SS, Fritz JM, Villarino AV, Zheng L, et al
    STAT5B: A Differential Regulator of the Life and Death of CD4(+) Effector Memory T Cells.
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    GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction.
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  202. SPROUSE ML, Shevchenko I, Scavuzzo MA, Joseph F, et al
    Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.
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  203. JUCHEM KW, Sacirbegovic F, Zhang C, Sharpe AH, et al
    PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-versus-Host Disease.
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  204. O'DONNELL JA, Lehman J, Roderick JE, Martinez-Marin D, et al
    Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
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  205. SUNDBLAD V, Morosi LG, Geffner JR, Rabinovich GA, et al
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    A Novel Pkhd1 Mutation Interacts with the Nonobese 1Diabetic Genetic Background To Cause Autoimmune Cholangitis.
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  207. BURG AR, Das S, Padgett LE, Koenig ZE, et al
    Superoxide Production by NADPH Oxidase Intensifies Macrophage Antiviral Responses during Diabetogenic Coxsackievirus Infection.
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  208. SATOOKA H, Nagakubo D, Sato T, Hirata T, et al
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  210. WHITENER RL, Gallo Knight L, Li J, Knapp S, et al
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  211. MACCUISH AC, Irvine WJ, Barnes EW, Duncan LJP, et al
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  214. ZHANG R, Sage PT, Finn K, Huynh A, et al
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    Broad Susceptibility of Nucleolar Proteins and Autoantigens to Complement C1 Protease Degradation.
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  216. SERRE L, Girard M, Ramadan A, Menut P, et al
    Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis.
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  217. POLLARD KM, Escalante GM, Huang H, Haraldsson KM, et al
    Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.
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  218. WANG Q, Racine JJ, Ratiu JJ, Wang S, et al
    Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy.
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  219. WEBB LM, Amici SA, Jablonski KA, Savardekar H, et al
    Correction: PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
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  220. KAMEKURA R, Takano K, Yamamoto M, Kawata K, et al
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  223. MADIREDDI S, Eun SY, Mehta AK, Birta A, et al
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  224. CHEN Y, Hu F, Dong X, Zhao M, et al
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  225. LOWNIK JC, Luker AJ, Damle SR, Cooley LF, et al
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  231. LEE T, Sprouse ML, Banerjee P, Bettini M, et al
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    Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.
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    Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology.
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    Cutting Edge: Dual TCRalpha Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation.
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