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  Autoimmune Disorders

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Articles published in J Immunol

Retrieve available abstracts of 218 articles:
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Single Articles


    May 2020
  1. QIU R, Yu X, Wang L, Han Z, et al
    Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity.
    J Immunol. 2020 May 15. pii: jimmunol.2000060. doi: 10.4049/jimmunol.2000060.
    PubMed     Abstract available


    April 2020
  2. THAPA M, Tedesco D, Gumber S, Elrod EJ, et al
    Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease.
    J Immunol. 2020 Apr 24. pii: jimmunol.1900391. doi: 10.4049/jimmunol.1900391.
    PubMed     Abstract available


  3. CHODISETTI SB, Fike AJ, Domeier PP, Schell SL, et al
    Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development.
    J Immunol. 2020 Apr 6. pii: jimmunol.2000170. doi: 10.4049/jimmunol.2000170.
    PubMed     Abstract available


    March 2020
  4. DENG Z, Law CS, Ho FO, Wang KM, et al
    A Defect in Thymic Tolerance Causes T Cell-Mediated Autoimmunity in a Murine Model of COPA Syndrome.
    J Immunol. 2020 Mar 20. pii: jimmunol.2000028. doi: 10.4049/jimmunol.2000028.
    PubMed     Abstract available


  5. HE X, Liu R, Fan T, Huang X, et al
    Treating Autoimmune Diseases by Targeting IL-23 with Gene-Silencing Pyrrole-Imidazole Polyamide.
    J Immunol. 2020 Mar 13. pii: jimmunol.1901215. doi: 10.4049/jimmunol.1901215.
    PubMed     Abstract available


  6. MATSUBARA H, Shimizu Y, Arai M, Yamagata A, et al
    PEPITEM/Cadherin 15 Axis Inhibits T Lymphocyte Infiltration and Glomerulonephritis in a Mouse Model of Systemic Lupus Erythematosus.
    J Immunol. 2020 Mar 13. pii: jimmunol.1900213. doi: 10.4049/jimmunol.1900213.
    PubMed     Abstract available


  7. CHEN J, Martindale JL, Abdelmohsen K, Kumar G, et al
    RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation.
    J Immunol. 2020 Mar 13. pii: jimmunol.1900769. doi: 10.4049/jimmunol.1900769.
    PubMed     Abstract available


    February 2020
  8. BERGOT AS, Buckle I, Cikaluru S, Naranjo JL, et al
    Regulatory T Cells Induced by Single-Peptide Liposome Immunotherapy Suppress Islet-Specific T Cell Responses to Multiple Antigens and Protect from Autoimmune Diabetes.
    J Immunol. 2020 Feb 28. pii: jimmunol.1901128. doi: 10.4049/jimmunol.1901128.
    PubMed     Abstract available


  9. LIU Z, Zhu L, Lu Z, Chen H, et al
    IL-37 Represses the Autoimmunity in Myasthenia Gravis via Directly Targeting Follicular Th and B Cells.
    J Immunol. 2020 Feb 28. pii: jimmunol.1901176. doi: 10.4049/jimmunol.1901176.
    PubMed     Abstract available


  10. WU CY, Hua KF, Chu CL, Yang SR, et al
    Tris DBA Ameliorates Accelerated and Severe Lupus Nephritis in Mice by Activating Regulatory T Cells and Autophagy and Inhibiting the NLRP3 Inflammasome.
    J Immunol. 2020 Feb 14. pii: jimmunol.1801610. doi: 10.4049/jimmunol.1801610.
    PubMed     Abstract available


  11. HUBER JE, Chang Y, Meinl I, Kumpfel T, et al
    Fingolimod Profoundly Reduces Frequencies and Alters Subset Composition of Circulating T Follicular Helper Cells in Multiple Sclerosis Patients.
    J Immunol. 2020 Feb 7. pii: jimmunol.1900955. doi: 10.4049/jimmunol.1900955.
    PubMed     Abstract available


    January 2020
  12. ZHU J, Hay AN, Potter AA, Richwine MW, et al
    Abrogated AID Function Prolongs Survival and Diminishes Renal Pathology in the BXSB Mouse Model of Systemic Lupus Erythematosus.
    J Immunol. 2020 Jan 27. pii: jimmunol.1900501. doi: 10.4049/jimmunol.1900501.
    PubMed     Abstract available


  13. CHEN HY, Wu YF, Chou FC, Wu YH, et al
    Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.
    J Immunol. 2020 Jan 22. pii: jimmunol.1901114. doi: 10.4049/jimmunol.1901114.
    PubMed     Abstract available


  14. KARPUS WJ
    Cytokines and Chemokines in the Pathogenesis of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2020;204:316-326.
    PubMed     Abstract available


  15. ANGIN M, Brignone C, Triebel F
    A LAG-3-Specific Agonist Antibody for the Treatment of T Cell-Induced Autoimmune Diseases.
    J Immunol. 2020 Jan 6. pii: jimmunol.1900823. doi: 10.4049/jimmunol.1900823.
    PubMed     Abstract available


  16. CHODISETTI SB, Fike AJ, Domeier PP, Singh H, et al
    Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity.
    J Immunol. 2020 Jan 3. pii: jimmunol.1901175. doi: 10.4049/jimmunol.1901175.
    PubMed     Abstract available


    December 2019
  17. WAN X, Pei W, Shahzad KA, Zhang L, et al
    Correction: A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide-Autoreactive CD4(+) and CD8(+) T Cells.
    J Immunol. 2019 Dec 23. pii: jimmunol.1901408. doi: 10.4049/jimmunol.1901408.
    PubMed    


  18. YOSHIMURA S, Thome R, Konno S, Mari ER, et al
    IL-9 Controls Central Nervous System Autoimmunity by Suppressing GM-CSF Production.
    J Immunol. 2019 Dec 18. pii: jimmunol.1801113. doi: 10.4049/jimmunol.1801113.
    PubMed     Abstract available


  19. SIMPSON SR, Rego SL, Harvey SE, Liu M, et al
    T Cells Produce IFN-alpha in the TREX1 D18N Model of Lupus-like Autoimmunity.
    J Immunol. 2019 Dec 11. pii: jimmunol.1900220. doi: 10.4049/jimmunol.1900220.
    PubMed     Abstract available


  20. TAHVILDARI M, Dana R
    Low-Dose IL-2 Therapy in Transplantation, Autoimmunity, and Inflammatory Diseases.
    J Immunol. 2019;203:2749-2755.
    PubMed     Abstract available


    November 2019
  21. ANDERSON W, Thorpe J, Long SA, Rawlings DJ, et al
    Efficient CRISPR/Cas9 Disruption of Autoimmune-Associated Genes Reveals Key Signaling Programs in Primary Human T Cells.
    J Immunol. 2019 Nov 13. pii: jimmunol.1900848. doi: 10.4049/jimmunol.1900848.
    PubMed     Abstract available


  22. BOVENSIEPEN CS, Schakat M, Sebode M, Zenouzi R, et al
    TNF-Producing Th1 Cells Are Selectively Expanded in Liver Infiltrates of Patients with Autoimmune Hepatitis.
    J Immunol. 2019 Nov 4. pii: jimmunol.1900124. doi: 10.4049/jimmunol.1900124.
    PubMed     Abstract available


    October 2019
  23. MARTIN K, Touil R, Kolb Y, Cvijetic G, et al
    Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity.
    J Immunol. 2019 Oct 28. pii: jimmunol.1900327. doi: 10.4049/jimmunol.1900327.
    PubMed     Abstract available


  24. ANDREAS N, Potthast M, Geiselhoringer AL, Garg G, et al
    RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells.
    J Immunol. 2019 Oct 2. pii: jimmunol.1801530. doi: 10.4049/jimmunol.1801530.
    PubMed     Abstract available


  25. DROHOMYRECKY PC, Doroshenko ER, Akkermann R, Moshkova M, et al
    Peroxisome Proliferator-Activated Receptor-delta Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2019 Oct 2. pii: jimmunol.1801200. doi: 10.4049/jimmunol.1801200.
    PubMed     Abstract available


    September 2019
  26. SHENG H, Marrero I, Maricic I, Fanchiang SS, et al
    Distinct PLZF(+)CD8alphaalpha(+) Unconventional T Cells Enriched in Liver Use a Cytotoxic Mechanism to Limit Autoimmunity.
    J Immunol. 2019 Sep 25. pii: jimmunol.1900832. doi: 10.4049/jimmunol.1900832.
    PubMed     Abstract available


  27. KAUSHANSKY N, Bakos E, Becker-Herman S, Shachar I, et al
    Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms.
    J Immunol. 2019 Sep 4. pii: jimmunol.1900424. doi: 10.4049/jimmunol.1900424.
    PubMed     Abstract available


    August 2019
  28. COLAMATTEO A, Maggioli E, Azevedo Loiola R, Hamid Sheikh M, et al
    Reduced Annexin A1 Expression Associates with Disease Severity and Inflammation in Multiple Sclerosis Patients.
    J Immunol. 2019 Aug 28. pii: jimmunol.1801683. doi: 10.4049/jimmunol.1801683.
    PubMed     Abstract available


  29. ENGLER JB, Heckmann NF, Jager J, Gold SM, et al
    Pregnancy Enables Expansion of Disease-Specific Regulatory T Cells in an Animal Model of Multiple Sclerosis.
    J Immunol. 2019 Aug 23. pii: jimmunol.1900611. doi: 10.4049/jimmunol.1900611.
    PubMed     Abstract available


  30. FRAUSSEN J, Marquez S, Takata K, Beckers L, et al
    Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD(-)CD27(-) Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients.
    J Immunol. 2019 Aug 7. pii: jimmunol.1801236. doi: 10.4049/jimmunol.1801236.
    PubMed     Abstract available


    July 2019
  31. ZHANG X, Kiapour N, Kapoor S, Khan T, et al
    IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2019 Jul 24. pii: jimmunol.1900311. doi: 10.4049/jimmunol.1900311.
    PubMed     Abstract available


  32. AKIYAMA C, Tsumiyama K, Uchimura C, Honda E, et al
    Conditional Upregulation of IFN-alpha Alone Is Sufficient to Induce Systemic Lupus Erythematosus.
    J Immunol. 2019 Jul 19. pii: jimmunol.1801617. doi: 10.4049/jimmunol.1801617.
    PubMed     Abstract available


  33. MARTINOV T, Swanson LA, Breed ER, Tucker CG, et al
    Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes.
    J Immunol. 2019 Jul 19. pii: jimmunol.1801535. doi: 10.4049/jimmunol.1801535.
    PubMed     Abstract available


  34. LIN Y, Cui C, Su M, Tian X, et al
    Skint8, a Novel B7 Family-Related Molecule, Negatively Regulates T Cell Responses.
    J Immunol. 2019;203:400-407.
    PubMed     Abstract available


  35. TITOV AA, Baker HV, Brusko TM, Sobel ES, et al
    Metformin Inhibits the Type 1 IFN Response in Human CD4(+) T Cells.
    J Immunol. 2019;203:338-348.
    PubMed     Abstract available


  36. LINDAHL H, Guerreiro-Cacais AO, Bedri SK, Linnerbauer M, et al
    IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.
    J Immunol. 2019 Jul 10. pii: jimmunol.1900400. doi: 10.4049/jimmunol.1900400.
    PubMed     Abstract available


    June 2019
  37. VASQUEZ M, Consuegra-Fernandez M, Aranda F, Jimenez A, et al
    Treatment of Experimental Autoimmune Encephalomyelitis by Sustained Delivery of Low-Dose IFN-alpha.
    J Immunol. 2019 Jun 17. pii: jimmunol.1801462. doi: 10.4049/jimmunol.1801462.
    PubMed     Abstract available


  38. GU BH, Sprouse ML, Madison MC, Hong MJ, et al
    A Novel Animal Model of Emphysema Induced by Anti-Elastin Autoimmunity.
    J Immunol. 2019 Jun 10. pii: jimmunol.1900113. doi: 10.4049/jimmunol.1900113.
    PubMed     Abstract available


    May 2019
  39. PIANCONE F, Saresella M, Marventano I, La Rosa F, et al
    A Deficit of CEACAM-1-Expressing T Lymphocytes Supports Inflammation in Primary Progressive Multiple Sclerosis.
    J Immunol. 2019 May 29. pii: jimmunol.1801625. doi: 10.4049/jimmunol.1801625.
    PubMed     Abstract available


  40. STOCKS BT, Wilson CS, Marshall AF, Hoopes EM, et al
    Regulation of Diabetogenic Immunity by IL15-Activated Regulatory CD8 T Cells in Type 1 Diabetes.
    J Immunol. 2019 May 24. pii: jimmunol.1800976. doi: 10.4049/jimmunol.1800976.
    PubMed     Abstract available


  41. PERPER SJ, Westmoreland SV, Karman J, Twomey R, et al
    Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus.
    J Immunol. 2019 May 20. pii: jimmunol.1900043. doi: 10.4049/jimmunol.1900043.
    PubMed     Abstract available


  42. JAMISON BL, Neef T, Goodspeed A, Bradley B, et al
    Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells.
    J Immunol. 2019 May 20. pii: jimmunol.1900127. doi: 10.4049/jimmunol.1900127.
    PubMed     Abstract available


  43. BUDZINSKI L, Schulz AR, Baumgart S, Burns T, et al
    Osmium-Labeled Microspheres for Bead-Based Assays in Mass Cytometry.
    J Immunol. 2019;202:3103-3112.
    PubMed     Abstract available


  44. FRANKS SE, Getahun A, Cambier JC
    A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation.
    J Immunol. 2019 May 10. pii: jimmunol.1801394. doi: 10.4049/jimmunol.1801394.
    PubMed     Abstract available


  45. CHU T, Ni M, Chen C, Akilesh S, et al
    Cutting Edge: BCAP Promotes Lupus-like Disease and TLR-Mediated Type I IFN Induction in Plasmacytoid Dendritic Cells.
    J Immunol. 2019;202:2529-2534.
    PubMed     Abstract available


    April 2019
  46. MATSUO T, Hashimoto M, Sakaguchi S, Sakaguchi N, et al
    Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation.
    J Immunol. 2019 Apr 24. pii: jimmunol.1801159. doi: 10.4049/jimmunol.1801159.
    PubMed     Abstract available


  47. KEGERREIS BJ, Catalina MD, Geraci NS, Bachali P, et al
    Genomic Identification of Low-Density Granulocytes and Analysis of Their Role in the Pathogenesis of Systemic Lupus Erythematosus.
    J Immunol. 2019 Apr 24. pii: jimmunol.1801512. doi: 10.4049/jimmunol.1801512.
    PubMed     Abstract available


  48. CURRAN CS, Sommers CL, Young HA, Bourcier K, et al
    Report on the 2018 Cancer, Autoimmunity, and Immunology Conference.
    J Immunol. 2019 Apr 15. pii: jimmunol.1900264. doi: 10.4049/jimmunol.1900264.
    PubMed     Abstract available


  49. HASELMAYER P, Camps M, Liu-Bujalski L, Nguyen N, et al
    Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models.
    J Immunol. 2019 Apr 15. pii: jimmunol.1800583. doi: 10.4049/jimmunol.1800583.
    PubMed     Abstract available


  50. BOXBERGER N, Hecker M, Zettl UK
    Dysregulation of Inflammasome Priming and Activation by MicroRNAs in Human Immune-Mediated Diseases.
    J Immunol. 2019;202:2177-2187.
    PubMed     Abstract available


  51. KOERS J, Derksen NIL, Ooijevaar-de Heer P, Nota B, et al
    Biased N-Glycosylation Site Distribution and Acquisition across the Antibody V Region during B Cell Maturation.
    J Immunol. 2019;202:2220-2228.
    PubMed     Abstract available


  52. MCLACHLAN SM, Aliesky HA, Rapoport B
    Nanoparticles Bearing TSH Receptor Protein and a Tolerogenic Molecule Do Not Induce Immune Tolerance but Exacerbate Thyroid Autoimmunity in hTSHR/NOD.H2(h4) Mice.
    J Immunol. 2019 Apr 3. pii: jimmunol.1900038. doi: 10.4049/jimmunol.1900038.
    PubMed     Abstract available


  53. BROWN MA, Su MA
    An Inconvenient Variable: Sex Hormones and Their Impact on T Cell Responses.
    J Immunol. 2019;202:1927-1933.
    PubMed     Abstract available


  54. AMROUCHE K, Pers JO, Jamin C
    Glatiramer Acetate Stimulates Regulatory B Cell Functions.
    J Immunol. 2019;202:1970-1980.
    PubMed     Abstract available


    March 2019
  55. HAO F, Tian M, Feng Y, Quan C, et al
    Correction: Abrogation of Lupus Nephritis in Somatic Hypermutation-Deficient B6.MRL-Fas(lpr)/J Mice.
    J Immunol. 2019 Mar 27. pii: jimmunol.1900198. doi: 10.4049/jimmunol.1900198.
    PubMed    


  56. MOUNTZ JD, Hsu HC, Ballesteros-Tato A
    Dysregulation of T Follicular Helper Cells in Lupus.
    J Immunol. 2019;202:1649-1658.
    PubMed     Abstract available


  57. RAHAMAN O, Bhattacharya R, Liu CSC, Raychaudhuri D, et al
    Cutting Edge: Dysregulated Endocannabinoid-Rheostat for Plasmacytoid Dendritic Cell Activation in a Systemic Lupus Endophenotype.
    J Immunol. 2019;202:1674-1679.
    PubMed     Abstract available


  58. STATHOPOULOS P, Chastre A, Waters P, Irani S, et al
    Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.
    J Immunol. 2019 Mar 1. pii: jimmunol.1801295. doi: 10.4049/jimmunol.1801295.
    PubMed     Abstract available


  59. GLATIGNY S, Hollbacher B, Motley SJ, Tan C, et al
    Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
    J Immunol. 2019;202:1373-1382.
    PubMed     Abstract available


    February 2019
  60. REYNOLDS CJ, Chong DLW, Li Y, Black SL, et al
    Bioluminescent Reporting of In Vivo IFN-gamma Immune Responses during Infection and Autoimmunity.
    J Immunol. 2019 Feb 27. pii: jimmunol.1801453. doi: 10.4049/jimmunol.1801453.
    PubMed     Abstract available


  61. LI R, Rezk A, Ghadiri M, Luessi F, et al
    Correction: Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis.
    J Immunol. 2019 Feb 15. pii: jimmunol.1900114. doi: 10.4049/jimmunol.1900114.
    PubMed    


  62. KHADER SA, Thirunavukkarasu S
    The Tale of IL-12 and IL-23: A Paradigm Shift.
    J Immunol. 2019;202:629-630.
    PubMed    


  63. BONEGIO RG, Lin JD, Beaudette-Zlatanova B, York MR, et al
    Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcgammaRIIA-Dependent but TLR-Independent Response.
    J Immunol. 2019;202:675-683.
    PubMed     Abstract available


  64. LOWNIK JC, Wimberly JL, Conrad DH, Martin RK, et al
    B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis.
    J Immunol. 2019;202:664-674.
    PubMed     Abstract available


  65. HE Z, Zhang J, Du Q, Xu J, et al
    SRC3 Is a Cofactor for RORgammat in Th17 Differentiation but Not Thymocyte Development.
    J Immunol. 2019;202:760-769.
    PubMed     Abstract available


    January 2019
  66. KIM D, Le HT, Nguyen QT, Kim S, et al
    Cutting Edge: IL-27 Attenuates Autoimmune Neuroinflammation via Regulatory T Cell/Lag3-Dependent but IL-10-Independent Mechanisms In Vivo.
    J Immunol. 2019 Jan 30. pii: jimmunol.1800898. doi: 10.4049/jimmunol.1800898.
    PubMed     Abstract available


  67. OUYANG S, Zeng Q, Tang N, Guo H, et al
    Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.
    J Immunol. 2019 Jan 28. pii: jimmunol.1701204. doi: 10.4049/jimmunol.1701204.
    PubMed     Abstract available


  68. DI DALMAZI G, Chalan P, Caturegli P
    MYMD-1, a Novel Immunometabolic Regulator, Ameliorates Autoimmune Thyroiditis via Suppression of Th1 Responses and TNF-alpha Release.
    J Immunol. 2019 Jan 23. pii: jimmunol.1801238. doi: 10.4049/jimmunol.1801238.
    PubMed     Abstract available


  69. DORRIS ER, Tazzyman SJ, Moylett J, Ramamoorthi N, et al
    The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation.
    J Immunol. 2019 Jan 18. pii: jimmunol.1801155. doi: 10.4049/jimmunol.1801155.
    PubMed     Abstract available


  70. QUAGLIA S, Ferrara F, De Leo L, Ziberna F, et al
    A Functional Idiotype/Anti-Idiotype Network Is Active in Genetically Gluten-Intolerant Individuals Negative for Both Celiac Disease-Related Intestinal Damage and Serum Autoantibodies.
    J Immunol. 2019 Jan 11. pii: jimmunol.1800819. doi: 10.4049/jimmunol.1800819.
    PubMed     Abstract available


  71. NIKITIN PA, Rose EL, Byun TS, Parry GC, et al
    C1s Inhibition by BIVV009 (Sutimlimab) Prevents Complement-Enhanced Activation of Autoimmune Human B Cells In Vitro.
    J Immunol. 2019 Jan 11. pii: jimmunol.1800998. doi: 10.4049/jimmunol.1800998.
    PubMed     Abstract available


  72. NIKOOPOUR E, Lin CM, Sheskey S, Heckenlively JR, et al
    Immune Cell Infiltration into the Eye Is Controlled by IL-10 in Recoverin-Induced Autoimmune Retinopathy.
    J Immunol. 2019 Jan 11. pii: jimmunol.1800574. doi: 10.4049/jimmunol.1800574.
    PubMed     Abstract available


  73. SKON-HEGG C, Zhang J, Wu X, Sagolla M, et al
    LACC1 Regulates TNF and IL-17 in Mouse Models of Arthritis and Inflammation.
    J Immunol. 2019;202:183-193.
    PubMed     Abstract available


    December 2018
  74. ARMBRUST T, Millis MP, Alvarez ML, Saremi A, et al
    CXCL4L1 Promoter Polymorphisms Are Associated with Improved Renal Function in Type 1 Diabetes.
    J Immunol. 2018 Dec 28. pii: jimmunol.1801086. doi: 10.4049/jimmunol.1801086.
    PubMed     Abstract available


  75. CAI Y, Yang C, Yu X, Qian J, et al
    Deficiency of beta-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.
    J Immunol. 2018 Dec 12. pii: jimmunol.1800261. doi: 10.4049/jimmunol.1800261.
    PubMed     Abstract available


  76. CLANCY RM, Halushka M, Rasmussen SE, Lhakhang T, et al
    Siglec-1 Macrophages and the Contribution of IFN to the Development of Autoimmune Congenital Heart Block.
    J Immunol. 2018 Dec 5. pii: jimmunol.1800357. doi: 10.4049/jimmunol.1800357.
    PubMed     Abstract available


  77. BISWAS PS
    IL-17 in Renal Immunity and Autoimmunity.
    J Immunol. 2018;201:3153-3159.
    PubMed     Abstract available


    November 2018
  78. JAMES EA, Gillette L, Durinovic-Bello I, Speake C, et al
    DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.
    J Immunol. 2018 Nov 19. pii: jimmunol.1800723. doi: 10.4049/jimmunol.1800723.
    PubMed     Abstract available


    October 2018
  79. HABIBULLAH M, Porter JA, Kluger N, Ranki A, et al
    Calcium-Sensing Receptor Autoantibodies in Patients with Autoimmune Polyendocrine Syndrome Type 1: Epitopes, Specificity, Functional Affinity, IgG Subclass, and Effects on Receptor Activity.
    J Immunol. 2018 Oct 31. pii: jimmunol.1701527. doi: 10.4049/jimmunol.1701527.
    PubMed     Abstract available


  80. DU SW, Jacobs HM, Arkatkar T, Rawlings DJ, et al
    Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells.
    J Immunol. 2018 Oct 29. pii: jimmunol.1800393. doi: 10.4049/jimmunol.1800393.
    PubMed     Abstract available


  81. LIN Q, Ohtsuji M, Amano H, Tsurui H, et al
    FcgammaRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus-Prone Yaa Mice.
    J Immunol. 2018 Oct 29. pii: jimmunol.1701487. doi: 10.4049/jimmunol.1701487.
    PubMed     Abstract available


  82. GARNIER L, Laffont S, Lelu K, Yogev N, et al
    Estrogen Signaling in Bystander Foxp3(neg) CD4(+) T Cells Suppresses Cognate Th17 Differentiation in Trans and Protects from Central Nervous System Autoimmunity.
    J Immunol. 2018 Oct 24. pii: jimmunol.1800417. doi: 10.4049/jimmunol.1800417.
    PubMed     Abstract available


  83. KAP YS, Bus-Spoor C, van Driel N, Dubbelaar ML, et al
    Targeted Diet Modification Reduces Multiple Sclerosis-like Disease in Adult Marmoset Monkeys from an Outbred Colony.
    J Immunol. 2018 Oct 19. pii: jimmunol.1800822. doi: 10.4049/jimmunol.1800822.
    PubMed     Abstract available


    September 2018
  84. YUAN Q, Li Y, Li J, Bian X, et al
    WDFY4 Involved in Symptoms of Systemic Lupus Erythematosus by Modulating B Cell Fate via Noncanonical Autophagy.
    J Immunol. 2018 Sep 26. pii: jimmunol.1800399. doi: 10.4049/jimmunol.1800399.
    PubMed     Abstract available


  85. HAMILTON JA, Wu Q, Yang P, Luo B, et al
    Cutting Edge: Intracellular IFN-beta and Distinct Type I IFN Expression Patterns in Circulating Systemic Lupus Erythematosus B Cells.
    J Immunol. 2018 Sep 10. pii: jimmunol.1800791. doi: 10.4049/jimmunol.1800791.
    PubMed     Abstract available


    August 2018
  86. NAPIER RJ, Lee EJ, Vance EE, Snow PE, et al
    Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis.
    J Immunol. 2018 Aug 27. pii: jimmunol.1700507. doi: 10.4049/jimmunol.1700507.
    PubMed     Abstract available


  87. PRESA M, Racine JJ, Dwyer JR, Lamont DJ, et al
    A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8(+) T Cells in NOD Mice.
    J Immunol. 2018 Aug 20. pii: jimmunol.1800465. doi: 10.4049/jimmunol.1800465.
    PubMed     Abstract available


  88. SPANGLER JB, Trotta E, Tomala J, Peck A, et al
    Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy.
    J Immunol. 2018 Aug 13. pii: jimmunol.1800578. doi: 10.4049/jimmunol.1800578.
    PubMed     Abstract available


    July 2018
  89. IHANTOLA EL, Viisanen T, Gazali AM, Nanto-Salonen K, et al
    Effector T Cell Resistance to Suppression and STAT3 Signaling during the Development of Human Type 1 Diabetes.
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    PubMed     Abstract available


  90. WAN X, Pei W, Shahzad KA, Zhang L, et al
    A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide-Autoreactive CD4(+) and CD8(+) T Cells.
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    PubMed     Abstract available


  91. GALICIA G, Lee DSW, Ramaglia V, Ward LA, et al
    Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda(-/-) and Ung(-/-) Mice.
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    PubMed     Abstract available


    June 2018
  92. OSSART J, Moreau A, Autrusseau E, Menoret S, et al
    Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy-Candiasis-Ectodermal Dystrophy-like Autoimmune Disease.
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    PubMed     Abstract available


  93. FELTON JL, Maseda D, Bonami RH, Hulbert C, et al
    Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes.
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    PubMed     Abstract available


  94. KATSUYAMA E, Yan M, Watanabe KS, Narazaki M, et al
    Correction: Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells.
    J Immunol. 2018 Jun 25. pii: jimmunol.1800810. doi: 10.4049/jimmunol.1800810.
    PubMed    


  95. JAYACHANDRAN N, Mejia EM, Sheikholeslami K, Sher AA, et al
    TAPP Adaptors Control B Cell Metabolism by Modulating the Phosphatidylinositol 3-Kinase Signaling Pathway: A Novel Regulatory Circuit Preventing Autoimmunity.
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    PubMed     Abstract available


  96. WOLF SJ, Theros J, Reed TJ, Liu J, et al
    TLR7-Mediated Lupus Nephritis Is Independent of Type I IFN Signaling.
    J Immunol. 2018 Jun 8. pii: jimmunol.1701588. doi: 10.4049/jimmunol.1701588.
    PubMed     Abstract available


  97. MONTEITH AJ, Vincent HA, Kang S, Li P, et al
    mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a.
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    PubMed     Abstract available


  98. SATO K, Honda SI, Shibuya A, Shibuya K, et al
    Cutting Edge: Identification of Marginal Reticular Cells as Phagocytes of Apoptotic B Cells in Germinal Centers.
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    PubMed     Abstract available


    May 2018
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    TCF-1 Inhibits IL-17 Gene Expression To Restrain Th17 Immunity in a Stage-Specific Manner.
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    PubMed     Abstract available


  100. GESTERMANN N, Di Domizio J, Lande R, Demaria O, et al
    Netting Neutrophils Activate Autoreactive B Cells in Lupus.
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    PubMed     Abstract available


  101. FERNANDO R, Grisolia ABD, Lu Y, Atkins S, et al
    Slit2 Modulates the Inflammatory Phenotype of Orbit-Infiltrating Fibrocytes in Graves' Disease.
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    PubMed     Abstract available


  102. VALENTINE KM, Davini D, Lawrence TJ, Mullins GN, et al
    CD8 Follicular T Cells Promote B Cell Antibody Class Switch in Autoimmune Disease.
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    PubMed     Abstract available


  103. HAO F, Tian M, Feng Y, Quan C, et al
    Abrogation of Lupus Nephritis in Somatic Hypermutation-Deficient MRL/lpr Mice.
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    PubMed     Abstract available


  104. CHOI SC, Xu Z, Li W, Yang H, et al
    Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4(+) T Cell Polarization.
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    PubMed     Abstract available


    April 2018
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    Vasoactive Intestinal Peptide Ameliorates Acute Myocarditis and Atherosclerosis by Regulating Inflammatory and Autoimmune Responses.
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    PubMed     Abstract available


  106. SCHLOSS J, Ali R, Racine JJ, Chapman HD, et al
    HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.
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    PubMed     Abstract available


  107. NYHOFF LE, Clark ES, Barron BL, Bonami RH, et al
    Bruton's Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages.
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    PubMed     Abstract available


    March 2018
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    Downregulation of CD3zeta in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype.
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    PubMed     Abstract available


  109. BELIKAN P, Buhler U, Wolf C, Pramanik GK, et al
    CCR7 on CD4(+) T Cells Plays a Crucial Role in the Induction of Experimental Autoimmune Encephalomyelitis.
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    PubMed     Abstract available


  110. JOAO C, Negi VS, Kazatchkine MD, Bayry J, et al
    Passive Serum Therapy to Immunomodulation by IVIG: A Fascinating Journey of Antibodies.
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  111. PODOJIL JR, Hecht I, Chiang MY, Vaknin I, et al
    ILDR2-Fc Is a Novel Regulator of Immune Homeostasis and Inducer of Antigen-Specific Immune Tolerance.
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  112. SPIRIG R, Campbell IK, Koernig S, Chen CG, et al
    rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcgammaRs.
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    PubMed     Abstract available


  113. O'DONNELL JA, Lehman J, Roderick JE, Martinez-Marin D, et al
    Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
    J Immunol. 2018 Mar 12. pii: jimmunol.1800240. doi: 10.4049/jimmunol.1800240.
    PubMed    


  114. SAGE PT, Schildberg FA, Sobel RA, Kuchroo VK, et al
    Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function.
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    PubMed     Abstract available


  115. DIXON KO, Schorer M, Nevin J, Etminan Y, et al
    Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity.
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    PubMed     Abstract available


    February 2018
  116. ZHANG R, Sage PT, Finn K, Huynh A, et al
    Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.
    J Immunol. 2018 Feb 23. pii: jimmunol.1800150. doi: 10.4049/jimmunol.1800150.
    PubMed    


  117. SAPIR Y, Vitenshtein A, Barsheshet Y, Zohar Y, et al
    Correction: A Fusion Protein Encoding the Second Extracellular Domain of CCR5 Arrests Chemokine-Induced Cosignaling and Effectively Suppresses Ongoing Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2018 Feb 21. pii: jimmunol.1800166. doi: 10.4049/jimmunol.1800166.
    PubMed    


    January 2018
  118. SMITH CJ, Allard DE, Wang Y, Howard JF Jr., et al
    IL-10 Paradoxically Promotes Autoimmune Neuropathy through S1PR1-Dependent CD4(+) T Cell Migration.
    J Immunol. 2018 Jan 24. pii: jimmunol.1701280. doi: 10.4049/jimmunol.1701280.
    PubMed     Abstract available



  119. Correction: NFAT1 Regulates Systemic Autoimmunity through the Modulation of a Dendritic Cell Property.
    J Immunol. 2018;200:880.
    PubMed    


  120. CORRADETTI C, Jog NR, Cesaroni M, Madaio M, et al
    Estrogen Receptor alpha Signaling Exacerbates Immune-Mediated Nephropathies through Alteration of Metabolic Activity.
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  121. ISEKA FM, Goetz BT, Mushtaq I, An W, et al
    Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function.
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  122. GUPTA S, Chan DW, Zaal KJ, Kaplan MJ, et al
    A High-Throughput Real-Time Imaging Technique To Quantify NETosis and Distinguish Mechanisms of Cell Death in Human Neutrophils.
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  123. YANG C, Lai W, Zhou J, Zheng X, et al
    Betaine Ameliorates Experimental Autoimmune Encephalomyelitis by Inhibiting Dendritic Cell-Derived IL-6 Production and Th17 Differentiation.
    J Immunol. 2018 Jan 12. pii: jimmunol.1700920. doi: 10.4049/jimmunol.1700920.
    PubMed     Abstract available


  124. BURRACK AL, Landry LG, Siebert J, Coulombe M, et al
    Simultaneous Recognition of Allogeneic MHC and Cognate Autoantigen by Autoreactive T Cells in Transplant Rejection.
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    PubMed     Abstract available


  125. JEONG HJ, Lee HJ, Ko JH, Cho BJ, et al
    Myeloid-Derived Suppressor Cells Mediate Inflammation Resolution in Humans and Mice with Autoimmune Uveoretinitis.
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    PubMed     Abstract available


  126. WILLING A, Jager J, Reinhardt S, Kursawe N, et al
    Production of IL-17 by MAIT Cells Is Increased in Multiple Sclerosis and Is Associated with IL-7 Receptor Expression.
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    PubMed     Abstract available


  127. MAJRI SS, Fritz JM, Villarino AV, Zheng L, et al
    STAT5B: A Differential Regulator of the Life and Death of CD4(+) Effector Memory T Cells.
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    December 2017
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    GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction.
    J Immunol. 2017 Dec 29. pii: jimmunol.1701484. doi: 10.4049/jimmunol.1701484.
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  129. SPROUSE ML, Shevchenko I, Scavuzzo MA, Joseph F, et al
    Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.
    J Immunol. 2017 Dec 27. pii: jimmunol.1700156. doi: 10.4049/jimmunol.1700156.
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  130. JUCHEM KW, Sacirbegovic F, Zhang C, Sharpe AH, et al
    PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-versus-Host Disease.
    J Immunol. 2017 Dec 6. pii: jimmunol.1701076. doi: 10.4049/jimmunol.1701076.
    PubMed     Abstract available


  131. O'DONNELL JA, Lehman J, Roderick JE, Martinez-Marin D, et al
    Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
    J Immunol. 2017 Dec 6. pii: jimmunol.1701229. doi: 10.4049/jimmunol.1701229.
    PubMed     Abstract available


  132. SUNDBLAD V, Morosi LG, Geffner JR, Rabinovich GA, et al
    Galectin-1: A Jack-of-All-Trades in the Resolution of Acute and Chronic Inflammation.
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    November 2017
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    A Novel Pkhd1 Mutation Interacts with the Nonobese 1Diabetic Genetic Background To Cause Autoimmune Cholangitis.
    J Immunol. 2017 Nov 20. pii: ji1701087. doi: 10.4049/jimmunol.1701087.
    PubMed     Abstract available


  134. BURG AR, Das S, Padgett LE, Koenig ZE, et al
    Superoxide Production by NADPH Oxidase Intensifies Macrophage Antiviral Responses during Diabetogenic Coxsackievirus Infection.
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    PubMed     Abstract available


  135. SATOOKA H, Nagakubo D, Sato T, Hirata T, et al
    The ERM Protein Moesin Regulates CD8(+) Regulatory T Cell Homeostasis and Self-Tolerance.
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  136. YANG M, Haase C, Viljanen J, Xu B, et al
    Cutting Edge: Processing of Oxidized Peptides in Macrophages Regulates T Cell Activation and Development of Autoimmune Arthritis.
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  137. WHITENER RL, Gallo Knight L, Li J, Knapp S, et al
    The Type 1 Diabetes-Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice.
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  138. MACCUISH AC, Irvine WJ, Barnes EW, Duncan LJP, et al
    Pillars Article: Antibodies to Pancreatic Islet Cells in Insulin-dependent Diabetics with Coexistent Autoimmune Disease. Lancet. 1974. 304: 1529-1531.
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  139. BOTTAZZO GF, Florin-Christensen A, Doniach D
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  140. BUCKNER JH, Greenbaum CJ
    Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.
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  141. ZHANG R, Sage PT, Finn K, Huynh A, et al
    B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.
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    October 2017
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    Broad Susceptibility of Nucleolar Proteins and Autoantigens to Complement C1 Protease Degradation.
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  143. SERRE L, Girard M, Ramadan A, Menut P, et al
    Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis.
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    PubMed     Abstract available


  144. POLLARD KM, Escalante GM, Huang H, Haraldsson KM, et al
    Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.
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    PubMed     Abstract available


  145. WANG Q, Racine JJ, Ratiu JJ, Wang S, et al
    Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy.
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  146. WEBB LM, Amici SA, Jablonski KA, Savardekar H, et al
    Correction: PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
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    PubMed    


  147. KAMEKURA R, Takano K, Yamamoto M, Kawata K, et al
    Cutting Edge: A Critical Role of Lesional T Follicular Helper Cells in the Pathogenesis of IgG4-Related Disease.
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  148. HAMILTON JA, Wu Q, Yang P, Luo B, et al
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    NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease.
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  150. MADIREDDI S, Eun SY, Mehta AK, Birta A, et al
    Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.
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  151. CHEN Y, Hu F, Dong X, Zhao M, et al
    SHIP-1 Deficiency in AID+ B Cells Leads to the Impaired Function of B10 Cells with Spontaneous Autoimmunity.
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  152. LOWNIK JC, Luker AJ, Damle SR, Cooley LF, et al
    ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses.
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    September 2017
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    NFAT1 Regulates Systemic Autoimmunity through the Modulation of a Dendritic Cell Property.
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    Pathogenic Role for gammadelta T Cells in Autoimmune Anti-Myeloperoxidase Glomerulonephritis.
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  155. HOSOKAWA T, Kimura T, Nada S, Okuno T, et al
    Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.
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    August 2017
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    Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity.
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  158. LEE T, Sprouse ML, Banerjee P, Bettini M, et al
    Ectopic Expression of Self-Antigen Drives Regulatory T Cell Development and Not Deletion of Autoimmune T Cells.
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    Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.
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    A Novel Subset of Anti-Inflammatory CD138+ Macrophages Is Deficient in Mice with Experimental Lupus.
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    The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
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    July 2017
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    Autoimmunity to Vimentin Is Associated with Outcomes of Patients with Idiopathic Pulmonary Fibrosis.
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    Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology.
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    Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity.
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    The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
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    Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to beta Cell Antigens Are Focused on a Unique Set of Epitopes.
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    TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy.
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    Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity.
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    IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus.
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    Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
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    A Novel alpha9 Integrin Ligand, XCL1/Lymphotactin, Is Involved in the Development of Murine Models of Autoimmune Diseases.
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    Cutting Edge: Origins, Recruitment, and Regulation of CD11c+ Cells in Inflamed Islets of Autoimmune Diabetes Mice.
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    Cutting Edge: Dual TCRalpha Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation.
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    Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes.
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    February 2017
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