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By B. S. Kamps et al.


  Autoimmune Disorders

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Articles published in J Immunol

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Single Articles


    February 2024
  1. KAGOHASHI K, Sasaki Y, Ozawa K, Tsuchiya T, et al
    Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation.
    J Immunol. 2024 Feb 5:ji2300202. doi: 10.4049/jimmunol.2300202.
    PubMed     Abstract available


  2. DUAN S, Li Q, Wang F, Kuang W, et al
    Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris.
    J Immunol. 2024;212:375-388.
    PubMed     Abstract available


    January 2024
  3. DAR AA, Ortega Y, Aktas S, Wu K, et al
    CRL4b Inhibition Ameliorates Experimental Autoimmune Encephalomyelitis Progression.
    J Immunol. 2024 Jan 24:ji2300754. doi: 10.4049/jimmunol.2300754.
    PubMed     Abstract available


  4. YANDAMURI SS, Filipek B, Lele N, Cohen I, et al
    A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases.
    J Immunol. 2024 Jan 22:ji2300015. doi: 10.4049/jimmunol.2300015.
    PubMed     Abstract available


  5. TOMALA J, Cao SD, Spangler JB
    Engineering Anticytokine Antibodies for Immune Modulation.
    J Immunol. 2024;212:225-234.
    PubMed     Abstract available


  6. HAN K, Xu J, Xie F, Crowther J, et al
    Engineering Strategies to Modulate the Gut Microbiome and Immune System.
    J Immunol. 2024;212:208-215.
    PubMed     Abstract available


  7. KLUG N, Burke J, Scott E
    Rational Engineering of Islet Tolerance via Biomaterial-Mediated Immune Modulation.
    J Immunol. 2024;212:216-224.
    PubMed     Abstract available


    December 2023
  8. FLYNN AL, Gans J, Escobedo J, Zhu C, et al
    RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function.
    J Immunol. 2023;211:1656-1668.
    PubMed     Abstract available


    November 2023
  9. SONI C, Makita S, Eichinger A, Serpas L, et al
    Cutting Edge: TLR2 Signaling in B Cells Promotes Autoreactivity to DNA via IL-6 Secretion.
    J Immunol. 2023;211:1475-1480.
    PubMed     Abstract available


  10. LU Y, Chiang J, Zhang R, Roche PA, et al
    TRAF6 and TRAF2/3 Binding Motifs in CD40 Differentially Regulate B Cell Function in T-Dependent Antibody Responses and Dendritic Cell Function in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 3:ji2300607. doi: 10.4049/jimmunol.2300607.
    PubMed     Abstract available


  11. MONSON N, Smith C, Greenberg H, Plumb P, et al
    VH2+ Antigen-Experienced B Cells in the Cerebrospinal Fluid Are Expanded and Enriched in Pediatric Anti-NMDA Receptor Encephalitis.
    J Immunol. 2023;211:1332-1339.
    PubMed     Abstract available


  12. AKBAR I, Tang R, Baillargeon J, Roy AP, et al
    Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 1:ji2300526. doi: 10.4049/jimmunol.2300526.
    PubMed     Abstract available


    October 2023
  13. RACINE JJ, Misherghi A, Dwyer JR, Maser R, et al
    HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice.
    J Immunol. 2023 Oct 25:ji2300303. doi: 10.4049/jimmunol.2300303.
    PubMed     Abstract available


  14. SOUKOU-WARGALLA S, Kilian C, Velasquez LN, Machicote A, et al
    Tr1 Cells Emerge and Suppress Effector Th17 Cells in Glomerulonephritis.
    J Immunol. 2023 Oct 18:ji2300305. doi: 10.4049/jimmunol.2300305.
    PubMed     Abstract available


  15. JORDAN TJM, Chen J, Li N, Burette S, et al
    The Eotaxin-1/CCR3 Axis and Matrix Metalloproteinase-9 Are Critical in Anti-NC16A IgE-Induced Bullous Pemphigoid.
    J Immunol. 2023;211:1216-1223.
    PubMed     Abstract available


  16. GILLES A, Hu L, Virdis F, Sant'Angelo DB, et al
    The MHC Class II Antigen-Processing and Presentation Pathway Is Dysregulated in Type 1 Diabetes.
    J Immunol. 2023 Oct 9:ji2300213. doi: 10.4049/jimmunol.2300213.
    PubMed     Abstract available


  17. MOK MY, Luo CY, Huang FP, Kong WY, et al
    IL-33 Orchestrated the Interaction and Immunoregulatory Functions of Alternatively Activated Macrophages and Regulatory T Cells In Vitro.
    J Immunol. 2023;211:1134-1143.
    PubMed     Abstract available


    September 2023
  18. NEW JS, Dizon BLP, King RG, Greenspan NS, et al
    B-1 B Cell-Derived Natural Antibodies against N-Acetyl-d-Glucosamine Suppress Autoimmune Diabetes Pathogenesis.
    J Immunol. 2023 Sep 25:ji2300264. doi: 10.4049/jimmunol.2300264.
    PubMed     Abstract available


  19. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Correction: Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
    J Immunol. 2023 Sep 11:ji2300549. doi: 10.4049/jimmunol.2300549.
    PubMed     Abstract available


  20. PARK YP, Roach T, Soh S, Zeumer-Spataro L, et al
    Molecular Mechanisms of Lupus Susceptibility Allele PBX1D.
    J Immunol. 2023;211:727-734.
    PubMed     Abstract available


    August 2023
  21. WILHELM CR, Upadhye MA, Eschbacher KL, Karandikar NJ, et al
    Proteolipid Protein-Induced Mouse Model of Multiple Sclerosis Requires B Cell-Mediated Antigen Presentation.
    J Immunol. 2023 Aug 7:ji2200721. doi: 10.4049/jimmunol.2200721.
    PubMed     Abstract available


    July 2023
  22. MATSUYAMA S, Yamamoto R, Murakami K, Takahashi N, et al
    GM-CSF Promotes the Survival of Peripheral-Derived Myeloid Cells in the Central Nervous System for Pain-Induced Relapse of Neuroinflammation.
    J Immunol. 2023;211:34-42.
    PubMed     Abstract available


    June 2023
  23. JAIN RW, Elliott DA, Yong VW
    Single Cell Analysis of High-Parameter Histology Images Using Histoflow Cytometry.
    J Immunol. 2023;210:2038-2049.
    PubMed     Abstract available


  24. SHEININ M, Mondal S, Roy A, Gorai S, et al
    Suppression of Experimental Autoimmune Encephalomyelitis in Mice by beta-Hydroxy beta-Methylbutyrate, a Body-Building Supplement in Humans.
    J Immunol. 2023 Jun 14:ji2200267. doi: 10.4049/jimmunol.2200267.
    PubMed     Abstract available


  25. ZHANG W, Mackay CR, Gershwin ME
    Immunomodulatory Effects of Microbiota-Derived Short-Chain Fatty Acids in Autoimmune Liver Diseases.
    J Immunol. 2023;210:1629-1639.
    PubMed     Abstract available


  26. SINGH SP, Parween F, Edara N, Zhang HH, et al
    Human CCR6+ Th Cells Show Both an Extended Stable Gradient of Th17 Activity and Imprinted Plasticity.
    J Immunol. 2023;210:1700-1716.
    PubMed     Abstract available


  27. BUZZELLI AA, McWilliams IL, Shin B, Bryars MT, et al
    Intrinsic STAT4 Expression Controls Effector CD4 T Cell Migration and Th17 Pathogenicity.
    J Immunol. 2023;210:1667-1676.
    PubMed     Abstract available


    May 2023
  28. RENSHAW L, Kim P, Crici M, Fazelinia H, et al
    The Ubiquitin Ligase Itch Skews Light Zone Selection in Germinal Centers.
    J Immunol. 2023;210:1473-1481.
    PubMed     Abstract available


    April 2023
  29. GREILACH SA, McIntyre LL, Nguyen QH, Silva J, et al
    Presentation of Human Neural Stem Cell Antigens Drives Regulatory T Cell Induction.
    J Immunol. 2023 Apr 21:ji2200798. doi: 10.4049/jimmunol.2200798.
    PubMed     Abstract available


  30. LEE PY, Cron RQ
    The Multifaceted Immunology of Cytokine Storm Syndrome.
    J Immunol. 2023;210:1015-1024.
    PubMed     Abstract available


  31. THOMPSON JW, Hu R, Huffaker TB, Ramstead AG, et al
    MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation.
    J Immunol. 2023;210:926-934.
    PubMed     Abstract available


    March 2023
  32. MOREEWS M, Mathieu AL, Pouxvielh K, Reuschle Q, et al
    mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.
    J Immunol. 2023 Mar 24:ji2200818. doi: 10.4049/jimmunol.2200818.
    PubMed     Abstract available


  33. MANJILI MH
    The Adaptation Model of Immunity: Signal IV Matters Most in Determining the Functional Outcomes of Immune Responses.
    J Immunol. 2023;210:521-530.
    PubMed     Abstract available


    February 2023
  34. ABBOUD G, Choi SC, Zhang X, Park YP, et al
    Glucose Requirement of Antigen-Specific Autoreactive B Cells and CD4+ T Cells.
    J Immunol. 2023;210:377-388.
    PubMed     Abstract available


  35. CIECKO AE, Wang Y, Harleston S, Drewek A, et al
    Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes.
    J Immunol. 2023 Feb 10:ji2200712. doi: 10.4049/jimmunol.2200712.
    PubMed     Abstract available


  36. SUBRAMANIAN K, Paul S, Libby A, Patterson J, et al
    HERV1-env Induces Unfolded Protein Response Activation in Autoimmune Liver Disease: A Potential Mechanism for Regulatory T Cell Dysfunction.
    J Immunol. 2023 Feb 1:ji2100186. doi: 10.4049/jimmunol.2100186.
    PubMed     Abstract available


    January 2023
  37. KIM D, Rai NK, Burrows A, Kim S, et al
    IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity.
    J Immunol. 2023 Jan 25:ji2200746. doi: 10.4049/jimmunol.2200746.
    PubMed     Abstract available


  38. RAPARIA C, Quach TD, Zeumer-Spataro L, Choi SC, et al
    Combination CTLA4Ig and Anti-CD40 Ligand Treatment Modifies T and B Cell Metabolic Profiles and Promotes B Cell Receptor Remodeling in a Mouse Model of Systemic Lupus Erythematosus.
    J Immunol. 2023 Jan 16:ji2100792. doi: 10.4049/jimmunol.2100792.
    PubMed     Abstract available


  39. HODGSON R, Crockford TL, Bhandari A, Kepple JD, et al
    Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-Like Autoimmunity.
    J Immunol. 2023 Jan 11:ji2200212. doi: 10.4049/jimmunol.2200212.
    PubMed     Abstract available


    December 2022
  40. LU Y, Xu M, Dorrier CE, Zhang R, et al
    CD40 Drives Central Nervous System Autoimmune Disease by Inducing Complementary Effector Programs via B Cells and Dendritic Cells.
    J Immunol. 2022;209:2083-2092.
    PubMed     Abstract available


  41. EMRALINO FL, Satoh S, Sakai N, Takami M, et al
    Double-Stranded RNA Induces Mortality in an MDA5-Mediated Type I Interferonopathy Model.
    J Immunol. 2022;209:2093-2103.
    PubMed     Abstract available


    November 2022
  42. WU Y, Chen D, Hu Y, Zhang S, et al
    Ring Finger Protein 215 Negatively Regulates Type I IFN Production via Blocking NF-kappaB p65 Activation.
    J Immunol. 2022;209:2012-2021.
    PubMed     Abstract available


  43. MATTER AL, Liggitt D, Goverman JM
    B Cells Drive MHC Class I-Restricted CD4 T Cells to Induce Spontaneous Central Nervous System Autoimmunity.
    J Immunol. 2022;209:1880-1891.
    PubMed     Abstract available


  44. WU Y, Chen D, Hu Y, Zhang S, et al
    Ring Finger Protein 215 Negatively Regulates Type I IFN Production via Blocking NF-kappaB p65 Activation.
    J Immunol. 2022;209:2012-2021.
    PubMed     Abstract available


  45. MURATA R, Kinoshita S, Matsuda K, Kawaguchi A, et al
    G307S DNAM-1 Mutation Exacerbates Autoimmune Encephalomyelitis via Enhancing CD4(+) T Cell Activation.
    J Immunol. 2022 Nov 2. pii: jimmunol.2200608. doi: 10.4049/jimmunol.2200608.
    PubMed     Abstract available


  46. MURATA R, Kinoshita S, Matsuda K, Kawaguchi A, et al
    G307S DNAM-1 Mutation Exacerbates Autoimmune Encephalomyelitis via Enhancing CD4+ T Cell Activation.
    J Immunol. 2022 Nov 2:ji2200608. doi: 10.4049/jimmunol.2200608.
    PubMed     Abstract available


    October 2022
  47. LU Y, Xu M, Dorrier CE, Zhang R, et al
    CD40 Drives Central Nervous System Autoimmune Disease by Inducing Complementary Effector Programs via B Cells and Dendritic Cells.
    J Immunol. 2022 Oct 12. pii: jimmunol.2200439. doi: 10.4049/jimmunol.2200439.
    PubMed     Abstract available


  48. MATTER AL, Liggitt D, Goverman JM
    B Cells Drive MHC Class I-Restricted CD4 T Cells to Induce Spontaneous Central Nervous System Autoimmunity.
    J Immunol. 2022 Oct 7. pii: jimmunol.2200494. doi: 10.4049/jimmunol.2200494.
    PubMed     Abstract available


  49. SONG J, Anderson W, Hu A, Obata-Ninomiya K, et al
    CBLB Deficiency in Human CD4(+) T Cells Results in Resistance to T Regulatory Suppression through Multiple Mechanisms.
    J Immunol. 2022;209:1260-1271.
    PubMed     Abstract available


    September 2022
  50. PARHAM KA, Tan XXS, Morelli DM, Chowdhury L, et al
    Pre-Germinal Center Interactions with T Cells Are Natural Checkpoints to Limit Autoimmune B Cell Responses.
    J Immunol. 2022 Sep 19. pii: jimmunol.2200534. doi: 10.4049/jimmunol.2200534.
    PubMed     Abstract available


  51. ZHANG Q, Liu Y, Liao J, Wu R, et al
    Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus.
    J Immunol. 2022 Sep 9. pii: jimmunol.2200307. doi: 10.4049/jimmunol.2200307.
    PubMed     Abstract available


  52. GAO M, Liu S, Chatham WW, Mountz JD, et al
    IL-4-Induced Quiescence of Resting Naive B Cells Is Disrupted in Systemic Lupus Erythematosus.
    J Immunol. 2022 Sep 7. pii: jimmunol.2200409. doi: 10.4049/jimmunol.2200409.
    PubMed     Abstract available


    August 2022
  53. WOODS J, Pemberton SE, Largent AD, Chiang K, et al
    Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction.
    J Immunol. 2022 Aug 22. pii: jimmunol.2100920. doi: 10.4049/jimmunol.2100920.
    PubMed     Abstract available


  54. TAYLOR TC, Li Y, Li DD, Majumder S, et al
    Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense.
    J Immunol. 2022 Aug 8. pii: jimmunol.2200132. doi: 10.4049/jimmunol.2200132.
    PubMed     Abstract available


  55. ZOU YR, Davidson A
    Nucleic Acid Sensing and Systemic Lupus Erythematosus: The Danger of Self.
    J Immunol. 2022;209:431-433.
    PubMed    


    July 2022
  56. CAO R, Li Z, Wu C, Ji S, et al
    Identification of a Small Molecule with Strong Anti-Inflammatory Activity in Experimental Autoimmune Encephalomyelitis and Sepsis through Blocking Gasdermin D Activation.
    J Immunol. 2022 Jul 29. pii: jimmunol.2100977. doi: 10.4049/jimmunol.2100977.
    PubMed     Abstract available


    June 2022
  57. CHANG J, Bouchard A, Bouklouch Y, Panneton V, et al
    ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation.
    J Immunol. 2022 Jun 27. pii: jimmunol.2100897. doi: 10.4049/jimmunol.2100897.
    PubMed     Abstract available


  58. DWYER JR, Racine JJ, Chapman HD, Quinlan A, et al
    Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells.
    J Immunol. 2022 Jun 27. pii: jimmunol.2100558. doi: 10.4049/jimmunol.2100558.
    PubMed     Abstract available


  59. KIAPOUR N, Wu B, Wang Y, Seyedsadr M, et al
    Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells.
    J Immunol. 2022 Jun 24. pii: jimmunol.2100176. doi: 10.4049/jimmunol.2100176.
    PubMed     Abstract available


  60. PODOJIL JR, Genardi S, Chiang MY, Kakade S, et al
    Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic beta Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice.
    J Immunol. 2022 Jun 20. pii: jimmunol.2200208. doi: 10.4049/jimmunol.2200208.
    PubMed     Abstract available


  61. MEIER LA, Faragher JL, Osinski V, Auger JL, et al
    CD47 Promotes Autoimmune Valvular Carditis by Impairing Macrophage Efferocytosis and Enhancing Cytokine Production.
    J Immunol. 2022;208:2643-2651.
    PubMed     Abstract available


  62. WONG KL, Li Z, Ma F, Wang D, et al
    SM03, an Anti-CD22 Antibody, Converts Cis-to-Trans Ligand Binding of CD22 against alpha2,6-Linked Sialic Acid Glycans and Immunomodulates Systemic Autoimmune Diseases.
    J Immunol. 2022 Jun 10. pii: jimmunol.2100820. doi: 10.4049/jimmunol.2100820.
    PubMed     Abstract available


    May 2022
  63. AKAMA-GARREN EH, Carroll MC
    Lupus Susceptibility Loci Predispose Mice to Clonal Lymphocytic Responses and Myeloid Expansion.
    J Immunol. 2022;208:2403-2424.
    PubMed     Abstract available


    April 2022
  64. KUMAR P, Balakrishnan S, Surendra Lele S, Setty S, et al
    Restoration of Follicular T-Regulatory/Helper Cell Balance by OX40L-JAG1 Cotreatment Suppresses Lupus Nephritis in NZBWF1/j Mice.
    J Immunol. 2022 Apr 25. pii: jimmunol.2200057. doi: 10.4049/jimmunol.2200057.
    PubMed     Abstract available


    March 2022
  65. BEN NASR M, Robbins D, Parone P, Usuelli V, et al
    Pharmacologically Enhanced Regulatory Hematopoietic Stem Cells Revert Experimental Autoimmune Diabetes and Mitigate Other Autoimmune Disorders.
    J Immunol. 2022 Mar 23. pii: jimmunol.2100949. doi: 10.4049/jimmunol.2100949.
    PubMed     Abstract available


  66. RICKASSEL C, Gnirck AC, Shaikh N, Adamiak V, et al
    Conventional NK Cells and Type 1 Innate Lymphoid Cells Do Not Influence Pathogenesis of Experimental Glomerulonephritis.
    J Immunol. 2022 Mar 16. pii: jimmunol.2101012. doi: 10.4049/jimmunol.2101012.
    PubMed     Abstract available


  67. YUZEFPOLSKIY Y, Morawski P, Fahning M, Speake C, et al
    Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine-Induced Immune Responses in Multiple Sclerosis Patients.
    J Immunol. 2022 Mar 14. pii: jimmunol.2101142. doi: 10.4049/jimmunol.2101142.
    PubMed     Abstract available


  68. LV J, Han M, Xiang Z, Gong R, et al
    Chlorzoxazone Alleviates Experimental Autoimmune Encephalomyelitis via Inhibiting IL-6 Secretion of Dendritic Cells.
    J Immunol. 2022 Mar 11. pii: jimmunol.2100169. doi: 10.4049/jimmunol.2100169.
    PubMed     Abstract available


  69. CHYUAN IT, Chu CL, Hsu CL, Pan MH, et al
    T Cell-Specific Deletion of TRAIL Receptor Reveals Its Critical Role for Regulating Pathologic T Cell Activation and Disease Induction in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2022 Mar 9. pii: jimmunol.2100788. doi: 10.4049/jimmunol.2100788.
    PubMed     Abstract available


  70. KAWANO S, Mitoma H, Inokuchi S, Yamauchi Y, et al
    TNFR2 Signaling Enhances Suppressive Abilities of Human Circulating T Follicular Regulatory Cells.
    J Immunol. 2022;208:1057-1065.
    PubMed     Abstract available


  71. SUN D, Chan N, Shao H, Born WK, et al
    gammadelta T Cells Activated in Different Inflammatory Environments Are Functionally Distinct.
    J Immunol. 2022;208:1224-1231.
    PubMed     Abstract available


    February 2022
  72. MANIVASAGAM S, Williams JL, Vollmer LL, Bollman B, et al
    Targeting IFN-lambda Signaling Promotes Recovery from Central Nervous System Autoimmunity.
    J Immunol. 2022 Feb 18. pii: jimmunol.2101041. doi: 10.4049/jimmunol.2101041.
    PubMed     Abstract available


  73. KIM S, Boehme L, Nel L, Casian A, et al
    Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell-like Differentiation in Patients with Granulomatosis with Polyangiitis.
    J Immunol. 2022;208:807-818.
    PubMed     Abstract available


  74. JIANG R, Qin Y, Wang Y, Xu X, et al
    Dynamic Number and Function of IL-10-Producing Regulatory B Cells in the Immune Microenvironment at Distinct Stages of Type 1 Diabetes.
    J Immunol. 2022 Feb 9. pii: jimmunol.2100357. doi: 10.4049/jimmunol.2100357.
    PubMed     Abstract available


  75. NOMURA H, Wada N, Takahashi H, Kase Y, et al
    IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse.
    J Immunol. 2022;208:582-593.
    PubMed     Abstract available


    January 2022
  76. JORGE AM, Lao T, Kim R, Licciardi S, et al
    SCARF1-Induced Efferocytosis Plays an Immunomodulatory Role in Humans, and Autoantibodies Targeting SCARF1 Are Produced in Patients with Systemic Lupus Erythematosus.
    J Immunol. 2022 Jan 26. pii: jimmunol.2100532. doi: 10.4049/jimmunol.2100532.
    PubMed     Abstract available


  77. LOMBARD-VADNAIS F, Collin R, Daudelin JF, Chabot-Roy G, et al
    The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes.
    J Immunol. 2022 Jan 17. pii: jimmunol.2100456. doi: 10.4049/jimmunol.2100456.
    PubMed     Abstract available


  78. JONES BE, Maerz MD, Bahnson HT, Somasundaram A, et al
    Fewer LAG-3(+) T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes.
    J Immunol. 2022 Jan 12. pii: jimmunol.2100850. doi: 10.4049/jimmunol.2100850.
    PubMed     Abstract available


    December 2021
  79. MERLO LMF, Peng W, DuHadaway JB, Montgomery JD, et al
    The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism.
    J Immunol. 2021 Dec 29. pii: jimmunol.2100705. doi: 10.4049/jimmunol.2100705.
    PubMed     Abstract available


  80. RENNA V, Surova E, Khadour A, Datta M, et al
    Defective Allelic Exclusion by IgD in the Absence of Autoantigen.
    J Immunol. 2021 Dec 20. pii: jimmunol.2100726. doi: 10.4049/jimmunol.2100726.
    PubMed     Abstract available


  81. MONTEITH AJ, Miller JM, Williams JM, Voss K, et al
    Altered Mitochondrial Homeostasis during Systemic Lupus Erythematosus Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating Staphylococcus aureus.
    J Immunol. 2021 Dec 20. pii: jimmunol.2100752. doi: 10.4049/jimmunol.2100752.
    PubMed     Abstract available


  82. INOUE M, Nakahama T, Yamasaki R, Shibuya T, et al
    An Aicardi-Goutieres Syndrome-Causative Point Mutation in Adar1 Gene Invokes Multiorgan Inflammation and Late-Onset Encephalopathy in Mice.
    J Immunol. 2021;207:3016-3027.
    PubMed     Abstract available


  83. CZEH M, Stable S, Kramer S, Tepe L, et al
    DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.
    J Immunol. 2021 Dec 13. pii: jimmunol.2100624. doi: 10.4049/jimmunol.2100624.
    PubMed     Abstract available


    November 2021
  84. WHITTINGTON KB, Prislovsky A, Beaty J, Albritton L, et al
    CD8(+) T Cells Expressing an HLA-DR1 Chimeric Antigen Receptor Target Autoimmune CD4(+) T Cells in an Antigen-Specific Manner and Inhibit the Development of Autoimmune Arthritis.
    J Immunol. 2021 Nov 24. pii: jimmunol.2100643. doi: 10.4049/jimmunol.2100643.
    PubMed     Abstract available


  85. O'CONNELL P, Blake MK, Godbehere S, Aldhamen YA, et al
    Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis.
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  86. LEE J, Cullum E, Stoltz K, Bachmann N, et al
    Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68.
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  87. HU Y, Chen G, Huang J, Li Z, et al
    The Calcium Channel Inhibitor Nimodipine Shapes the Uveitogenic T Cells and Protects Mice from Experimental Autoimmune Uveitis through the p38-MAPK Signaling Pathway.
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  88. ALLENSPACH EJ, Shubin NJ, Cerosaletti K, Mikacenic C, et al
    The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.
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  89. CHUNG H, Komada T, Lau A, Chappellaz M, et al
    AIM2 Suppresses Inflammation and Epithelial Cell Proliferation during Glomerulonephritis.
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  90. TSE BCY, Ireland RA, Lee JY, Marsh-Wakefield F, et al
    Exposure to Systemic Immunosuppressive Ultraviolet Radiation Alters T Cell Recirculation through Sphingosine-1-Phosphate.
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    October 2021
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    B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-lambda in Systemic Lupus Erythematosus.
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  92. WELIWITIGODA A, Palle P, Gessner M, Hubbard NW, et al
    Cutting Edge: DOCK8 Regulates a Subset of Dendritic Cells That Is Critical for the Development of Experimental Autoimmune Encephalomyelitis.
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  93. LI M, Itoh A, Xi J, Yu C, et al
    Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides.
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    September 2021
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    Cutting Edge: A Threshold of B Cell Costimulatory Signals Is Required for Spontaneous Germinal Center Formation in Autoimmunity.
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  95. ARAKAWA A, Reeves E, Vollmer S, Arakawa Y, et al
    ERAP1 Controls the Autoimmune Response against Melanocytes in Psoriasis by Generating the Melanocyte Autoantigen and Regulating Its Amount for HLA-C*06:02 Presentation.
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  96. MANDEL-BREHM C, Fichtner ML, Jiang R, Winton VJ, et al
    Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes.
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  97. CIECKO AE, Schauder DM, Foda B, Petrova G, et al
    Self-Renewing Islet TCF1(+) CD8 T Cells Undergo IL-27-Controlled Differentiation to Become TCF1(-) Terminal Effectors during the Progression of Type 1 Diabetes.
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  98. ZHOU M, Dascani P, Ding C, Kos JT, et al
    Integrin CD11b Negatively Regulates B Cell Receptor Signaling to Shape Humoral Response during Immunization and Autoimmunity.
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    August 2021
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    CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein-Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response.
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    Activation of Transcription Factor 4 in Dendritic Cells Controls Th1/Th17 Responses and Autoimmune Neuroinflammation.
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  102. PERRY DJ, Peters LD, Lakshmi PS, Zhang L, et al
    Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4(+) T Cell Activation.
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    July 2021
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    Defining the Glycosaminoglycan Interactions of Complement Factor H-Related Protein 5.
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    June 2021
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    Meningeal B Cell Clusters Correlate with Submeningeal Pathology in a Natural Model of Multiple Sclerosis.
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  107. NEEDHAM EJ, Stoevesandt O, Thelin EP, Zetterberg H, et al
    Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury.
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  108. ZHANG J, Bouch RJ, Blekhman MG, He Z, et al
    USP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity.
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    Timing Effect of Adenosine-Directed Immunomodulation on Mouse Experimental Autoimmune Uveitis.
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    Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.
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    Targeting of Deciduous Tooth Pulp Stem Cell-Derived Extracellular Vesicles on Telomerase-Mediated Stem Cell Niche and Immune Regulation in Systemic Lupus Erythematosus.
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    May 2021
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    Context-Dependent miR-21 Regulation of TLR7-Mediated Autoimmune and Foreign Antigen-Driven Antibody-Forming Cell and Germinal Center Responses.
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  113. CHALAN P, Thomas N, Caturegli P
    Th17 Cells Contribute to the Pathology of Autoimmune Hypophysitis.
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  114. CAI H, Liu X, Zhang F, Han QY, et al
    G3BP1 Inhibition Alleviates Intracellular Nucleic Acid-Induced Autoimmune Responses.
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    Identification of a Long Noncoding RNA TRAF3IP2-AS1 as Key Regulator of IL-17 Signaling through the SRSF10-IRF1-Act1 Axis in Autoimmune Diseases.
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    Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation.
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    April 2021
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    Characterization of a TNFR2-Selective Agonistic TNF-alpha Mutant and Its Derivatives as an Optimal Regulatory T Cell Expander.
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  119. PAN W, Nagpal K, Suarez-Fueyo A, Ferretti A, et al
    The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway.
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  120. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
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  121. JOHNSON BM, Uchimura T, Gallovic MD, Thamilarasan M, et al
    STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways.
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  122. LANGRISH CL, Bradshaw JM, Francesco MR, Owens TD, et al
    Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.
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    Nrf2 through Aryl Hydrocarbon Receptor Regulates IL-22 Response in CD4(+) T Cells.
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    TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus.
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    March 2021
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    A Functionally Distinct CXCR3(+)/IFN-gamma(+)/IL-10(+) Subset Defines Disease-Suppressive Myelin-Specific CD8 T Cells.
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    Insulin Receptor-Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice.
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  127. CHEN L, Bai J, Peng D, Gao Y, et al
    SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2alpha to Suppress Th17 Cell Differentiation.
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    Structure and Functional Characterization of a Humanized Anti-CCL20 Antibody following Exposure to Serum Reveals the Formation of Immune Complex That Leads to Toxicity.
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    February 2021
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    CD4(+)CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum.
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    January 2021
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    Immune Cell-Stromal Circuitry in Lupus Photosensitivity.
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  131. SUMIYOSHI M, Kotani Y, Ikuta Y, Suzue K, et al
    Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation.
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    November 2020
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    T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
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  133. HAYES ET, Hagan CE, Khoryati L, Gavin MA, et al
    Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function.
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