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By B. S. Kamps et al.


  Breast Cancer

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Articles published in Clin Cancer Res

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Single Articles


    June 2024
  1. JANK P, Karn T, van Mackelenbergh M, Lindner J, et al
    An analysis of PIK3CA hotspot mutations and response to neoadjuvant therapy in breast cancer patients from four prospective clinical trials.
    Clin Cancer Res. 2024 Jun 5. doi: 10.1158/1078-0432.CCR-24-0459.
    PubMed     Abstract available


  2. ZHANG Q, Cai Z, Gerratana L, Davis AA, et al
    Early evaluation of risk stratification and clinical outcomes for patients with advanced breast cancer through combined monitoring of baseline circulating tumor cells and DNA.
    Clin Cancer Res. 2024 Jun 3. doi: 10.1158/1078-0432.CCR-24-0535.
    PubMed     Abstract available


  3. MAKHLIN I, Demissei BG, D'Agostino R, Hundley WG, et al
    Statins Do Not Significantly Affect Oxidative Nitrosative Stress Biomarkers in the PREVENT Randomized Clinical Trial.
    Clin Cancer Res. 2024;30:2370-2376.
    PubMed     Abstract available


    May 2024
  4. GOUGH SM, Flanagan JJ, Teh J, Andreoli M, et al
    Oral estrogen receptor PROTAC(R) vepdegestrant (ARV-471) is highly efficacious as monotherapy and in combination with CDK4/6 or PI3K/mTOR pathway inhibitors in preclinical ER+ breast cancer models.
    Clin Cancer Res. 2024 May 31. doi: 10.1158/1078-0432.CCR-23-3465.
    PubMed     Abstract available


  5. CHEUNG A, Chenoweth AM, Johansson A, Laddach R, et al
    Anti-EGFR antibody-drug conjugate carrying an inhibitor targeting CDK restricts triple-negative breast cancer growth.
    Clin Cancer Res. 2024 May 21. doi: 10.1158/1078-0432.CCR-23-3110.
    PubMed     Abstract available


  6. HADDAD TC, Suman VJ, Giridhar KV, Sideras K, et al
    Anastrozole dose escalation for optimal estrogen suppression in postmenopausal early-stage breast cancer: A prospective trial.
    Clin Cancer Res. 2024 May 16. doi: 10.1158/1078-0432.CCR-24-0341.
    PubMed     Abstract available


  7. WANDER SA, Bardia A
    Cracking the Genomic Code of CDK4/6 Inhibitor Resistance.
    Clin Cancer Res. 2024;30:2008-2010.
    PubMed     Abstract available


  8. BARDIA A, Sun S, Thimmiah N, Coates JT, et al
    Antibody Drug Conjugate Sacituzumab Govitecan Enables A Sequential TOP1/PARP Inhibitor Cancer Therapy Strategy in Breast Cancer Patients.
    Clin Cancer Res. 2024 May 6. doi: 10.1158/1078-0432.CCR-24-0428.
    PubMed     Abstract available


    April 2024
  9. BOTTOSSO M, Miglietta F, Vernaci GM, Giarratano T, et al
    Gene-expression assays to tailor adjuvant endocrine therapy for HR+/HER2- breast cancer.
    Clin Cancer Res. 2024 Apr 24. doi: 10.1158/1078-0432.CCR-23-4020.
    PubMed     Abstract available


  10. IWASE T, Cohen EN, Gao H, Alexander A, et al
    Maintenance pembrolizumab therapy in patients with metastatic HER2-negative breast cancer with prior response to chemotherapy.
    Clin Cancer Res. 2024 Apr 17. doi: 10.1158/1078-0432.CCR-23-2947.
    PubMed     Abstract available


  11. MOYER CL, Lanier A, Qian J, Coleman D, et al
    IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy.
    Clin Cancer Res. 2024 Apr 5. doi: 10.1158/1078-0432.CCR-23-3839.
    PubMed     Abstract available


  12. HAN YJ, Liu S, Hardeman A, Rajagopal PS, et al
    The VEGF-Hypoxia Signature is Upregulated in Basal like Breast Tumors from Women of African Ancestry and Associated with Poor Outcomes in Breast Cancer.
    Clin Cancer Res. 2024 Apr 2. doi: 10.1158/1078-0432.CCR-23-1526.
    PubMed     Abstract available


  13. CONNOLLY RM, Wang V, Hyman DM, Grivas P, et al
    Trastuzumab and Pertuzumab in Patients with Non-Breast/Gastroesophageal HER2-Amplified Tumors: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol J.
    Clin Cancer Res. 2024;30:1273-1280.
    PubMed     Abstract available


    March 2024
  14. MAGBANUA MJM, Ahmed Z, Sayaman RW, Brown Swigart L, et al
    Cell-free DNA concentration as a biomarker of response and recurrence in HER2-negative breast cancer receiving neoadjuvant chemotherapy.
    Clin Cancer Res. 2024 Mar 12. doi: 10.1158/1078-0432.CCR-23-2928.
    PubMed     Abstract available


  15. MARTIN M, Yoder R, Salgado R, Del Monte-Millan M, et al
    Tumor-infiltrating lymphocytes refine outcomes in triple-negative breast cancer treated with anthracycline-free neoadjuvant chemotherapy.
    Clin Cancer Res. 2024 Mar 11. doi: 10.1158/1078-0432.CCR-24-0106.
    PubMed     Abstract available


    February 2024
  16. GUARDUCCI C, Nardone A, Russo D, Nagy Z, et al
    Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer.
    Clin Cancer Res. 2024 Feb 21. doi: 10.1158/1078-0432.CCR-23-2975.
    PubMed     Abstract available


  17. MAMOUNAS EP, Bandos H, Rastogi P, Zhang Y, et al
    Breast Cancer Index and Prediction of Extended Aromatase Inhibitor Therapy Benefit in Hormone Receptor-positive Breast Cancer from the NRG Oncology/NSABP B-42 Trial.
    Clin Cancer Res. 2024 Feb 20. doi: 10.1158/1078-0432.CCR-23-1977.
    PubMed     Abstract available


  18. BARTLETT JMS, Xu K, Wong J, Pond G, et al
    Validation of the prognostic performance of Breast Cancer Index (BCI) in hormone receptor-positive (HR+) postmenopausal breast cancer patients in the TEAM trial.
    Clin Cancer Res. 2024 Feb 12. doi: 10.1158/1078-0432.CCR-23-2436.
    PubMed     Abstract available


    January 2024
  19. TAN TJ, Sammons S, Im YH, She L, et al
    Phase II DORA Study of Olaparib with or without Durvalumab as a Chemotherapy-Free Maintenance Strategy in Platinum-Pretreated Advanced Triple-Negative Breast Cancer.
    Clin Cancer Res. 2024 Jan 18. doi: 10.1158/1078-0432.CCR-23-2513.
    PubMed     Abstract available


    December 2023
  20. MCTIERNAN A
    Diet Matters in Breast Cancer Prognosis: Clinical Trial Evidence and Questions.
    Clin Cancer Res. 2023 Dec 20. doi: 10.1158/1078-0432.CCR-23-3195.
    PubMed     Abstract available


  21. ALBAIN KS, Yau C, Petricoin EF, Wolf DM, et al
    Neoadjuvant trebananib plus paclitaxel-based chemotherapy for stage II/III breast cancer in the adaptively randomized I-SPY2 trial - Efficacy and biomarker discovery.
    Clin Cancer Res. 2023 Dec 18. doi: 10.1158/1078-0432.CCR-22-2256.
    PubMed     Abstract available


  22. CALVO V, Zheng W, Adam-Artigues A, Staschke KA, et al
    A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response-Dependent Survival of Quiescent Cancer Cells.
    Clin Cancer Res. 2023;29:5155-5172.
    PubMed     Abstract available


  23. COAKLEY M, Villacampa G, Sritharan P, Swift C, et al
    Comparison of circulating tumor DNA assays for Molecular Residual Disease detection in early-stage triple negative breast cancer.
    Clin Cancer Res. 2023 Dec 11. doi: 10.1158/1078-0432.CCR-23-2326.
    PubMed     Abstract available


  24. SCHMID P, Turner NC, Barrios CH, Isakoff SJ, et al
    First-Line Ipatasertib, Atezolizumab, and Taxane Triplet for Metastatic Triple-Negative Breast Cancer: Clinical and Biomarker Results.
    Clin Cancer Res. 2023 Dec 7. doi: 10.1158/1078-0432.CCR-23-2084.
    PubMed     Abstract available


  25. KIM H, Whitman AA, Wisniewska K, Kakati RT, et al
    Tamoxifen Response at Single-Cell Resolution in Estrogen Receptor-Positive Primary Human Breast Tumors.
    Clin Cancer Res. 2023;29:4894-4907.
    PubMed     Abstract available


    November 2023
  26. CESCON DW, Hilton J, Morales Murilo S, Layman RM, et al
    A Phase I/II Study of GSK525762 Combined With Fulvestrant in Patients With Hormone Receptor-Positive/HER2-Negative (HR+/HER2-) Advanced or Metastatic Breast Cancer.
    Clin Cancer Res. 2023 Nov 22. doi: 10.1158/1078-0432.CCR-23-0133.
    PubMed     Abstract available


  27. PRAT A, Solovieff N, Andre F, O'Shaughnessy J, et al
    Intrinsic subtype and overall survival of patients with advanced HR+/HER2- breast cancer treated with ribociclib and ET: correlative analysis of MONALEESA-2, -3, -7.
    Clin Cancer Res. 2023 Nov 8. doi: 10.1158/1078-0432.CCR-23-0561.
    PubMed     Abstract available


  28. WILDIERS H, Armstrong A, Cuypere E, Dalenc F, et al
    Paclitaxel plus Eftilagimod Alpha, a Soluble LAG-3 Protein, in Metastatic, HR+ Breast Cancer: Results from AIPAC, a Randomized, Placebo Controlled Phase 2b Trial.
    Clin Cancer Res. 2023 Nov 8. doi: 10.1158/1078-0432.CCR-23-1173.
    PubMed     Abstract available


  29. JHAVERI KL, Bellet-Ezquerra M, Turner NC, Loi S, et al
    Phase Ia/b Study of Giredestrant +/-Palbociclib and +/-Luteinizing Hormone-releasing Hormone Agonists in Estrogen Receptor-positive, HER2-negative, Locally Advanced/Metastatic Breast Cancer.
    Clin Cancer Res. 2023 Nov 3. doi: 10.1158/1078-0432.CCR-23-1796.
    PubMed     Abstract available


  30. ROLFO C, Del Re M, Russo A
    Empower the Potential of Trastuzumab Deruxtecan with Novel Combinations.
    Clin Cancer Res. 2023;29:4317-4319.
    PubMed     Abstract available


    October 2023
  31. TOLANEY SM, Goel S, Nadal J, Denys H, et al
    Overall survival and exploratory biomarker analyses of abemaciclib plus trastuzumab with or without fulvestrant vs trastuzumab plus chemotherapy in HR+, HER2+ metastatic breast cancer patients.
    Clin Cancer Res. 2023 Oct 31. doi: 10.1158/1078-0432.CCR-23-1209.
    PubMed     Abstract available


  32. CONFORTI F, Pala L, De Pas T, Zattarin E, et al
    Fine-Tuning Adjuvant Endocrine Therapy for Early-Stage Breast Cancer: An Expert Consensus on Open Issues for Future Research.
    Clin Cancer Res. 2023 Oct 31. doi: 10.1158/1078-0432.CCR-23-1836.
    PubMed     Abstract available


  33. GOETZ MP, Hamilton EP, Campone M, Hurvitz SA, et al
    Landscape of baseline and acquired genomic alterations in circulating tumor DNA with abemaciclib alone or with endocrine therapy in advanced breast cancer.
    Clin Cancer Res. 2023 Oct 27. doi: 10.1158/1078-0432.CCR-22-3573.
    PubMed     Abstract available


  34. CONTE B, Boni L, Bisagni G, Durando A, et al
    SNPs of aromatase predict long-term survival and aromatase inhibitor toxicity in patients with early breast cancer: a biomarker analysis of the GIM4 and GIM5 trials.
    Clin Cancer Res. 2023 Oct 27. doi: 10.1158/1078-0432.CCR-23-1568.
    PubMed     Abstract available


  35. WILKERSON AD, Parthasarathy PB, Stabellini N, Mitchell C, et al
    Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer.
    Clin Cancer Res. 2023 Oct 26. doi: 10.1158/1078-0432.CCR-23-1349.
    PubMed     Abstract available


  36. BERRINO F, Villarini A, Gargano G, Krogh V, et al
    The effect of Diet on Breast Cancer recurrence: the DIANA-5 randomized trial.
    Clin Cancer Res. 2023 Oct 17. doi: 10.1158/1078-0432.CCR-23-1615.
    PubMed     Abstract available


  37. HUANG H, Yao Y, Shen L, Jiang J, et al
    CD24hiCD27+Bregs within metastatic lymph nodes promote multi-drug resistance in breast cancer.
    Clin Cancer Res. 2023 Oct 13. doi: 10.1158/1078-0432.CCR-23-1759.
    PubMed     Abstract available


  38. HUPPERT LA, Rugo HS
    Can We De-escalate Therapy for HER2-Positive Metastatic Breast Cancer?
    Clin Cancer Res. 2023 Oct 2. doi: 10.1158/1078-0432.CCR-23-1909.
    PubMed     Abstract available


    September 2023
  39. RING A, Kilburn LS, Pearson A, Moretti L, et al
    Olaparib and celarasertib (AZD6738) in patients with triple negative advanced breast cancer: results from Cohort E of the plasmaMATCH trial (CRUK/15/010).
    Clin Cancer Res. 2023 Sep 29. doi: 10.1158/1078-0432.CCR-23-1696.
    PubMed     Abstract available


  40. JOAQUIN GARCIA A, Rediti M, Venet D, Majjaj S, et al
    Differential benefit of metronomic chemotherapy among triple negative breast cancer subtypes treated in the IBCSG Trial 22-00.
    Clin Cancer Res. 2023 Sep 21. doi: 10.1158/1078-0432.CCR-23-1267.
    PubMed     Abstract available


  41. CAO X, Muller KE, Chamberlin MD, Gui J, et al
    Near-infrared spectral tomography for predicting residual cancer burden during early stage neoadjuvant chemotherapy for breast cancer.
    Clin Cancer Res. 2023 Sep 21. doi: 10.1158/1078-0432.CCR-23-1593.
    PubMed     Abstract available


  42. LINK T, Blohmer JU, Schmitt WD, Kuhlmann JD, et al
    RANK expression as an independent predictor for response to neoadjuvant chemotherapy in luminal-like breast cancer - a translational insight from the GeparX trial.
    Clin Cancer Res. 2023 Sep 19. doi: 10.1158/1078-0432.CCR-23-1801.
    PubMed     Abstract available


  43. CROSBY EJ, Hartman ZC, Lyerly HK
    Beyond Neoantigens: Antigens Derived from Tumor Drivers as Cancer Vaccine Targets.
    Clin Cancer Res. 2023;29:3256-3258.
    PubMed     Abstract available


    August 2023
  44. GAO JJ, Osgood CL, Feng Z, Bloomquist EW, et al
    FDA Approval Summary: Ribociclib Indicated for Male Patients with Hormone Receptor-Positive, HER2-Negative Advanced or Metastatic Breast Cancer.
    Clin Cancer Res. 2023 Aug 18:CCR-23-1133. doi: 10.1158/1078-0432.CCR-23-1133.
    PubMed     Abstract available


  45. TEW BY, Kalfa AJ, Yang Z, Hurth KM, et al
    ATM-inhibitor AZD1390 is a radiosensitizer for breast cancer CNS metastasis.
    Clin Cancer Res. 2023 Aug 16:CCR-23-0290. doi: 10.1158/1078-0432.CCR-23-0290.
    PubMed     Abstract available


  46. TOVEY H, Sipos O, Parker JS, Hoadley KA, et al
    Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727).
    Clin Cancer Res. 2023 Aug 14:OF1-OF15. doi: 10.1158/1078-0432.CCR-23-0370.
    PubMed     Abstract available


  47. DEGNIM AC, Siontis BL, Ahmed SK, Hoskin TL, et al
    Trimodality Therapy Improves Disease Control in Radiation-Associated Angiosarcoma of the Breast.
    Clin Cancer Res. 2023;29:2885-2893.
    PubMed     Abstract available


    July 2023
  48. PASCUAL J, Gil-Gil M, Proszek P, Zielinski C, et al
    Baseline mutations and ctDNA dynamics as prognostic and predictive factors in ER-positive/HER2-negative metastatic breast cancer patients.
    Clin Cancer Res. 2023 Jul 25:CCR-23-0956. doi: 10.1158/1078-0432.CCR-23-0956.
    PubMed     Abstract available


  49. MEDFORD AJ, Moy B, Spring LM, Hurvitz SA, et al
    Molecular Residual Disease in Breast Cancer: Detection and Therapeutic Interception.
    Clin Cancer Res. 2023 Jul 21:CCR-23-0757. doi: 10.1158/1078-0432.CCR-23-0757.
    PubMed     Abstract available


  50. LEFRERE H, Moore K, Floris G, Sanders J, et al
    Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features.
    Clin Cancer Res. 2023 Jul 14:CCR-22-3645. doi: 10.1158/1078-0432.CCR-22-3645.
    PubMed     Abstract available


  51. TRAPHAGEN NA, Schwartz GN, Tau S, Roberts AM, et al
    Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer.
    Clin Cancer Res. 2023 Jul 13:CCR-23-0488. doi: 10.1158/1078-0432.CCR-23-0488.
    PubMed     Abstract available


  52. STOLAROVA L, Kleiblova P, Zemankova P, Stastna B, et al
    ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk.
    Clin Cancer Res. 2023 Jul 13:OF1-OF14. doi: 10.1158/1078-0432.CCR-23-0212.
    PubMed     Abstract available


  53. WILLIAMS TM, Schneeweiss A, Jackisch C, Shen C, et al
    Caveolin gene expression predicts clinical outcomes for early-stage HER2-negative breast cancer treated with paclitaxel-based chemotherapy in the GeparSepto trial.
    Clin Cancer Res. 2023 Jul 11:CCR-23-0362. doi: 10.1158/1078-0432.CCR-23-0362.
    PubMed     Abstract available


  54. MIGLIETTA F, Ragazzi M, Fernandes B, Griguolo G, et al
    A prognostic model based on residual cancer burden and tumor-infiltrating lymphocytes on residual disease after neoadjuvant therapy in HER2+ breast cancer.
    Clin Cancer Res. 2023 Jul 7:CCR-23-0480. doi: 10.1158/1078-0432.CCR-23-0480.
    PubMed     Abstract available


  55. RAGHAV KPS, Moasser MM
    Molecular Pathways and Mechanisms of HER2 in Cancer Therapy.
    Clin Cancer Res. 2023;29:2351-2361.
    PubMed     Abstract available


  56. MARON SB, Chatila W, Walch H, Chou JF, et al
    Determinants of survival in HER2+ metastatic esophagogastric cancer.
    Clin Cancer Res. 2023 Jul 5:CCR-22-3769. doi: 10.1158/1078-0432.CCR-22-3769.
    PubMed     Abstract available


    June 2023
  57. SHAGISULTANOVA E, Gradishar W, Brown-Glabberman U, Chalasani P, et al
    Safety and efficacy of tucatinib, letrozole and palbociclib in patients with previously treated HR+/HER2+ breast cancer.
    Clin Cancer Res. 2023 Jun 26:CCR-23-0117. doi: 10.1158/1078-0432.CCR-23-0117.
    PubMed     Abstract available


  58. CASAK SJ, Horiba MN, Yuan M, Cheng J, et al
    FDA Approval Summary: Tucatinib with trastuzumab for advanced unresectable or metastatic, chemotherapy refractory, HER2 positive RAS wild type colorectal cancer.
    Clin Cancer Res. 2023 Jun 15:CCR-23-1041. doi: 10.1158/1078-0432.CCR-23-1041.
    PubMed     Abstract available


  59. KABRAJI S, Lin NU
    Keeping it in the family: HER3 as a target in brain metastases.
    Clin Cancer Res. 2023 Jun 12:CCR-23-1107. doi: 10.1158/1078-0432.CCR-23-1107.
    PubMed     Abstract available


  60. RAO X, Chen Y, Beyrer J, Nash Smyth E, et al
    Clinical and Genomic Characteristics of Patients with HR+, HER2- Metastatic Breast Cancer Following Progression on a CDK4 and 6 Inhibitor.
    Clin Cancer Res. 2023 Jun 8:CCR-22-3843. doi: 10.1158/1078-0432.CCR-22-3843.
    PubMed     Abstract available


  61. HENSING WL, Gerratana L, Clifton K, Medford AJ, et al
    Genetic alterations detected by circulating tumor DNA in HER2-low metastatic breast cancer.
    Clin Cancer Res. 2023 Jun 2:CCR-22-3785. doi: 10.1158/1078-0432.CCR-22-3785.
    PubMed     Abstract available


  62. CHANDARLAPATY S, Dickler MN, Perez Fidalgo JA, Villanueva-Vazquez R, et al
    An open-label phase I study of GDC-0927 in postmenopausal women with locally advanced or metastatic estrogen receptor positive breast cancer.
    Clin Cancer Res. 2023 Jun 1:CCR-23-0011. doi: 10.1158/1078-0432.CCR-23-0011.
    PubMed     Abstract available


  63. SCHWARTZ GN, Kaufman PA, Giridhar KV, Marotti JD, et al
    Alternating 17beta-Estradiol and Aromatase Inhibitor Therapies Is Efficacious in Postmenopausal Women with Advanced Endocrine-Resistant ER+ Breast Cancer.
    Clin Cancer Res. 2023 Jun 1:OF1-OF7. doi: 10.1158/1078-0432.CCR-23-0112.
    PubMed     Abstract available


    May 2023
  64. VEERARAGHAVAN J, Gutierrez C, De Angelis C, Davis R, et al
    A multiparameter molecular classifier to predict response to neoadjuvant lapatinib plus trastuzumab without chemotherapy in HER2+ breast cancer.
    Clin Cancer Res. 2023 May 17:CCR-22-3753. doi: 10.1158/1078-0432.CCR-22-3753.
    PubMed     Abstract available


  65. SCHWARTZ GN, Kaufman PA, Giridhar KV, Marotti JD, et al
    Alternating 17beta-estradiol and aromatase inhibitor therapies is efficacious in post-menopausal women with advanced endocrine-resistant ER+ breast cancer.
    Clin Cancer Res. 2023 May 15:CCR-23-0112. doi: 10.1158/1078-0432.CCR-23-0112.
    PubMed     Abstract available


  66. STENMARK TULLBERG A, Sjostrom M, Nimeus E, Killander F, et al
    Integrating Tumor-Intrinsic and Immunologic Factors to Identify Immunogenic Breast Cancers from a Low-Risk Cohort: Results from the Randomized SweBCG91RT Trial.
    Clin Cancer Res. 2023;29:1783-1793.
    PubMed     Abstract available


  67. RASSY E, Garberis I, Tran-Dien A, Job B, et al
    Comparative Genomic Profiling of Second Breast Cancers following First Ipsilateral Hormone Receptor-Positive Breast Cancers.
    Clin Cancer Res. 2023;29:1822-1831.
    PubMed     Abstract available


    April 2023
  68. GIBSON CJ, Fell GG, Sella T, Sperling AS, et al
    Clonal Hematopoiesis in Young Women Treated for Breast Cancer.
    Clin Cancer Res. 2023 Apr 28:CCR-23-0050. doi: 10.1158/1078-0432.CCR-23-0050.
    PubMed     Abstract available


  69. DISIS ML, Dang Y, Coveler AL, Childs JS, et al
    A Phase I/II trial of HER-2/neu vaccine primed autologous T-cell infusions in patients with treatment refractory HER-2/neu overexpressing breast cancer.
    Clin Cancer Res. 2023 Apr 24:CCR-22-3578. doi: 10.1158/1078-0432.CCR-22-3578.
    PubMed     Abstract available


  70. CLARK AS, Hong F, Finn RS, DeMichele AM, et al
    Phase II Study of Palbociclib (PD-0332991) in CCND1, 2, or 3 Amplification: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1B.
    Clin Cancer Res. 2023;29:1477-1483.
    PubMed     Abstract available


  71. TOMASICH E, Steindl A, Paiato C, Hatziioannou T, et al
    Frequent overexpression of HER3 in brain metastases from breast and lung cancer.
    Clin Cancer Res. 2023 Apr 10:CCR-23-0020. doi: 10.1158/1078-0432.CCR-23-0020.
    PubMed     Abstract available


  72. FASCHING PA, Szeto C, Denkert C, Benz S, et al
    Inferred immune-cell activity is an independent predictor of HER2 negative breast cancer prognosis and response to paclitaxel-based therapy in the GeparSepto trial.
    Clin Cancer Res. 2023 Apr 4:CCR-22-2213. doi: 10.1158/1078-0432.CCR-22-2213.
    PubMed     Abstract available


    March 2023
  73. LINDEN HM, Mankoff DA
    Can Molecular Imaging Find a Path to Navigate Evolving Breast Cancer Treatments?
    Clin Cancer Res. 2023 Mar 29:CCR-23-0393. doi: 10.1158/1078-0432.CCR-23-0393.
    PubMed     Abstract available


  74. TAU S, Miller TW
    Alpelisib Efficacy without Cherry-PI3King Mutations.
    Clin Cancer Res. 2023;29:989-990.
    PubMed     Abstract available


  75. SIVAKUMAR S, Jin DX, Rathod R, Ross J, et al
    Genetic Heterogeneity and Tissue-specific Patterns of Tumors with Multiple PIK3CA Mutations.
    Clin Cancer Res. 2023;29:1125-1136.
    PubMed     Abstract available


  76. RUGO HS, Raskina K, Schrock AB, Madison RW, et al
    Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma.
    Clin Cancer Res. 2023;29:1056-1067.
    PubMed     Abstract available


    February 2023
  77. GRAESER M, Gluz O, Biehl C, Ulbrich-Gebauer D, et al
    Impact of RNA Signatures on pCR and Survival after 12-Week Neoadjuvant Pertuzumab plus Trastuzumab with or without Paclitaxel in the WSG-ADAPT HER2+/HR- Trial.
    Clin Cancer Res. 2023;29:805-814.
    PubMed     Abstract available


  78. GUERRERO-ZOTANO A, Belli S, Zielinski C, Gil-Gil M, et al
    CCNE1 and PLK1 mediates resistance to palbociclib in HR+/HER2- metastatic breast cancer.
    Clin Cancer Res. 2023 Feb 7:CCR-22-2206. doi: 10.1158/1078-0432.CCR-22-2206.
    PubMed     Abstract available


  79. IQBAL R, Yaqub M, Bektas HO, Oprea-Lager DE, et al
    [18F]FDG and [18F]FES PET/CT Imaging as a Biomarker for Therapy Effect in Patients with Metastatic ER+ Breast Cancer Undergoing Treatment with Rintodestrant.
    Clin Cancer Res. 2023 Feb 3:CCR-22-2720. doi: 10.1158/1078-0432.CCR-22-2720.
    PubMed     Abstract available


  80. DENKERT C, Lambertini C, Fasching PA, Pogue-Geile KL, et al
    Biomarker Data From the Phase III KATHERINE Study of Adjuvant T-DM1 Versus Trastuzumab for Residual Invasive Disease After Neoadjuvant Therapy for HER2-Positive Breast Cancer.
    Clin Cancer Res. 2023 Feb 2:CCR-22-1989. doi: 10.1158/1078-0432.CCR-22-1989.
    PubMed     Abstract available


    January 2023
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    December 2022
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