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  Breast Cancer

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Articles published in Ann Oncol

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Single Articles


    March 2020
  1. MAVROUDIS D, Saloustros E, Malamos N, Kakolyris S, et al
    Corrigendum to Six versus 12 months of adjuvant trastuzumab in combination with dose-dense chemotherapy for women with HER2-positive breast cancer: a multicenter randomized study by the Hellenic Oncology Research Group (HORG): Annals of Oncology, Volu
    Ann Oncol. 2020;31:444-445.
    PubMed     Text format    


  2. MOSS J, Zick A, Grinshpun A, Carmon E, et al
    Circulating breast-derived DNA allows universal detection and monitoring of localized breast cancer.
    Ann Oncol. 2020;31:395-403.
    PubMed     Text format     Abstract available


  3. BARROSO-SOUSA R, Jain E, Cohen O, Kim D, et al
    Prevalence and mutational determinants of high tumor mutation burden in breast cancer.
    Ann Oncol. 2020;31:387-394.
    PubMed     Text format     Abstract available


  4. MOSELE F, Stefanovska B, Lusque A, Tran Dien A, et al
    Outcome and molecular landscape of patients with PIK3CA-mutated metastatic breast cancer.
    Ann Oncol. 2020;31:377-386.
    PubMed     Text format     Abstract available


    February 2020
  5. BJELIC-RADISIC V, Cardoso F, Cameron D, Brain E, et al
    An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45.
    Ann Oncol. 2020;31:283-288.
    PubMed     Text format     Abstract available


    January 2020
  6. HEIL J, Kuerer HM, Pfob A, Rauch G, et al
    Eliminating the breast cancer surgery paradigm after neoadjuvant systemic therapy: current evidence and future challenges.
    Ann Oncol. 2020;31:61-71.
    PubMed     Text format     Abstract available


    December 2019
  7. BRANDAO M, Caparica R, Eiger D, de Azambuja E, et al
    Biomarkers of response and resistance to PI3K inhibitors in estrogen receptor-positive breast cancer patients and combination therapies involving PI3K inhibitors.
    Ann Oncol. 2019;30.
    PubMed     Text format     Abstract available


  8. VERRET B, Cortes J, Bachelot T, Andre F, et al
    Efficacy of PI3K inhibitors in advanced breast cancer.
    Ann Oncol. 2019;30.
    PubMed     Text format     Abstract available


  9. VASAN N, Toska E, Scaltriti M
    Overview of the relevance of PI3K pathway in HR-positive breast cancer.
    Ann Oncol. 2019;30.
    PubMed     Text format     Abstract available


  10. VASAN N, Toska E, Scaltriti M
    Overview of the relevance of PI3K pathway in HR-positive breast cancer.
    Ann Oncol. 2019;30 Suppl 10:x3-x11.
    PubMed     Text format     Abstract available


  11. BRANDAO M, Caparica R, Eiger D, de Azambuja E, et al
    Biomarkers of response and resistance to PI3K inhibitors in estrogen receptor-positive breast cancer patients and combination therapies involving PI3K inhibitors.
    Ann Oncol. 2019;30 Suppl 10:x27-x42.
    PubMed     Text format     Abstract available


  12. VERRET B, Cortes J, Bachelot T, Andre F, et al
    Efficacy of PI3K inhibitors in advanced breast cancer.
    Ann Oncol. 2019;30 Suppl 10:x12-x20.
    PubMed     Text format     Abstract available


  13. PARK YH, Lee SJ, Cho EY, La Choi Y, et al
    Clinical relevance of TNM staging system according to breast cancer subtypes.
    Ann Oncol. 2019;30:2011.
    PubMed     Text format    


  14. DUBSKY P, Montagna G, Ritter M
    Lymphocyte infiltration predicts survival in chemotherapy-naive, triple-negative breast cancer and identifies patients with intrinsically good prognosis: have we been bringing owls to Athens?
    Ann Oncol. 2019;30:1849-1850.
    PubMed     Text format    


    November 2019
  15. HORTOBAGYI GN, Stemmer SM, Burris HA, Yap YS, et al
    Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer.
    Ann Oncol. 2019;30:1842.
    PubMed     Text format    


  16. FERREIRA AR, Di Meglio A, Pistilli B, Gbenou AS, et al
    Differential impact of endocrine therapy and chemotherapy on quality of life of breast cancer survivors: a prospective patient-reported outcomes analysis.
    Ann Oncol. 2019;30:1784-1795.
    PubMed     Text format     Abstract available


  17. BARTLETT JMS, Sgroi DC, Treuner K, Zhang Y, et al
    Breast Cancer Index and prediction of benefit from extended endocrine therapy in breast cancer patients treated in the Adjuvant Tamoxifen-To Offer More? (aTTom) trial.
    Ann Oncol. 2019;30:1776-1783.
    PubMed     Text format     Abstract available


    October 2019
  18. DUBSKY P, Montagna G, Ritter M
    Lymphocyte infiltration predicts survival in chemotherapy-naive, triple negative breast cancer, and identifies patients with intrinsically good prognosis: Have we been bringing owls to Athens?
    Ann Oncol. 2019 Oct 18. pii: 5593649. doi: 10.1093.
    PubMed     Text format    


  19. FERREIRA AR, Di Meglio A, Pistilli B, Gbenou AS, et al
    Differential impact of endocrine therapy and chemotherapy on quality of life of breast cancer survivors: a prospective patient-reported outcomes analysis.
    Ann Oncol. 2019 Oct 8. pii: 5583691. doi: 10.1093.
    PubMed     Text format     Abstract available


  20. CARDOSO F, Kyriakides S, Ohno S, Penault-Llorca F, et al
    Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Ann Oncol. 2019;30:1674.
    PubMed     Text format    


  21. BURSTEIN HJ, Curigliano G, Loibl S, Dubsky P, et al
    Estimating the benefits of therapy for early-stage breast cancer: the St. Gallen International Consensus Guidelines for the primary therapy of early breast cancer 2019.
    Ann Oncol. 2019;30:1541-1557.
    PubMed     Text format     Abstract available


  22. ARNEDOS M, Gligorov J
    St Gallen International Consensus Guidelines in early breast cancer: experts to prevent patients' overtreatment and breaking the bank?
    Ann Oncol. 2019;30:1533-1535.
    PubMed     Text format    


    August 2019
  23. BARTLETT JMS, Sgroi DC, Treuner K, Zhang Y, et al
    Breast Cancer Index and Prediction of Benefit from Extended Endocrine Therapy in Breast Cancer Patients Treated in the Adjuvant Tamoxifen - To Offer More? (aTTom) Trial.
    Ann Oncol. 2019 Aug 28. pii: 5555808. doi: 10.1093.
    PubMed     Text format     Abstract available


  24. ARNEDOS M, Gligorov J
    St Gallen international consensus guidelines in early breast cancer: Experts to prevent patients' overtreatment and breaking the bank?
    Ann Oncol. 2019 Aug 27. pii: 5555359. doi: 10.1093.
    PubMed     Text format    


  25. PARK YH, Lee SJ, Cho EY, La Choi Y, et al
    Clinical relevance of TNM staging system according to breast cancer subtypes.
    Ann Oncol. 2019 Aug 13. pii: 5549411. doi: 10.1093.
    PubMed     Text format    


  26. HORTOBAGYI GN, Stemmer SM, Burris HA, Yap YS, et al
    Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer.
    Ann Oncol. 2019 Aug 13. pii: 5548997. doi: 10.1093.
    PubMed     Text format    


  27. SRINIVASALU VK, Susan A, Philip A, Jose WM, et al
    147P Clinical significance of BCL-2 with basal and non-basal triple negative breast cancer (TNBC).
    Ann Oncol. 2019 Aug 2. pii: 5543073. doi: 10.1093.
    PubMed     Text format    


  28. BURSTEIN HJ, Curigliano G, Loibl S, Dubsky P, et al
    Estimating the Benefits of Therapy for Early Stage Breast Cancer The St Gallen International Consensus Guidelines for the Primary Therapy of Early Breast Cancer 2019.
    Ann Oncol. 2019 Aug 2. pii: 5543097. doi: 10.1093.
    PubMed     Text format     Abstract available


  29. SRINIVASALU VK, Susan A, Jose WM, Philip A, et al
    41P Prognostic significance of BCL-2 expression in triple negative breast cancer (TNBC).
    Ann Oncol. 2019 Aug 2. pii: 5543072. doi: 10.1093.
    PubMed     Text format    


    July 2019
  30. LOI S
    The ESMO clinical practise guidelines for early breast cancer: diagnosis, treatment and follow-up: on the winding road to personalized medicine.
    Ann Oncol. 2019 Jul 9. pii: 5530161. doi: 10.1093.
    PubMed     Text format    


  31. CURIGLIANO G, Burstein HJ, P Winer E, Gnant M, et al
    Corrections to "De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017".
    Ann Oncol. 2019;30:1181.
    PubMed     Text format    


  32. LOIBL S, Majewski I, Guarneri V, Nekljudova V, et al
    Corrections to "PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab".
    Ann Oncol. 2019;30:1180.
    PubMed     Text format    


  33. CORTES J, Calvo V, Ramirez-Merino N, O'Shaughnessy J, et al
    Corrections to "Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis".
    Ann Oncol. 2019;30:1179.
    PubMed     Text format    


  34. PASCUAL J, Turner NC
    Targeting the PI3-kinase pathway in triple-negative breast cancer.
    Ann Oncol. 2019;30:1051-1060.
    PubMed     Text format     Abstract available


  35. MATIKAS A, Foukakis T, Swain S, Bergh J, et al
    Avoiding over- and undertreatment in patients with resected node-positive breast cancer with the use of gene expression signatures: are we there yet?
    Ann Oncol. 2019;30:1044-1050.
    PubMed     Text format     Abstract available


  36. FOULKES WD, Polak P
    Journey's end: the quest for BRCA-like hereditary breast cancer genes is nearly over.
    Ann Oncol. 2019;30:1023-1025.
    PubMed     Text format    


    June 2019
  37. CARDOSO F, Kyriakides S, Ohno S, Penault-Llorca F, et al
    Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Ann Oncol. 2019 Jun 24. pii: 5522519. doi: 10.1093.
    PubMed     Text format    


  38. CARDOSO F, Kyriakides S, Ohno S, Penault-Llorca F, et al
    Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Ann Oncol. 2019 Jun 4. pii: 5499075. doi: 10.1093.
    PubMed     Text format    


    May 2019
  39. OLIVEIRA M, Saura C, Nuciforo P, Calvo I, et al
    FAIRLANE, a double-blind placebo-controlled randomized phase II trial of neoadjuvant ipatasertib plus paclitaxel for early triple-negative breast cancer.
    Ann Oncol. 2019 May 30. pii: 5506637. doi: 10.1093.
    PubMed     Text format     Abstract available


  40. LOIBL S, Untch M, Burchardi N, Huober J, et al
    A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple negative breast cancer - clinical results and biomarker analysis of GeparNuevo study.
    Ann Oncol. 2019 May 16. pii: 5490226. doi: 10.1093.
    PubMed     Text format     Abstract available


  41. FOULKES WD, Polak P
    Journey's End: the quest for BRCA-like hereditary breast cancer genes is nearly over.
    Ann Oncol. 2019 May 15. pii: 5489599. doi: 10.1093.
    PubMed     Text format    


  42. MALVEZZI M, Carioli G, Bertuccio P, Boffetta P, et al
    Reply to the Letter to the Editor: "European cancer mortality predictions for the year 2019 with focus on breast cancer, by Malvezzi M et al." by J. Marsden, H. Hamoda, On behalf of the British Menopause Society Medical Advisory Council.
    Ann Oncol. 2019 May 9. pii: 5487409. doi: 10.1093.
    PubMed     Text format    


  43. MARSDEN J, Hamoda H
    European cancer mortality predictions for the year 2019 with focus on breast cancer, by Malvezzi M et al. (Ann Oncol 2019; 30: doi.org/10.1093/annonc/mdz051).
    Ann Oncol. 2019 May 9. pii: 5482565. doi: 10.1093.
    PubMed     Text format    


  44. PASCUAL J, Turner NC
    Targeting the PI3-kinase pathway in triple negative breast cancer.
    Ann Oncol. 2019 May 3. pii: 5485241. doi: 10.1093.
    PubMed     Text format     Abstract available


  45. MALVEZZI M, Carioli G, Bertuccio P, Boffetta P, et al
    European cancer mortality predictions for the year 2019 with focus on breast cancer.
    Ann Oncol. 2019;30:781-787.
    PubMed     Text format     Abstract available


  46. TURNER NC, Alarcon E, Armstrong AC, Philco M, et al
    BEECH: a dose-finding run-in followed by a randomised phase II study assessing the efficacy of AKT inhibitor capivasertib (AZD5363) combined with paclitaxel in patients with estrogen receptor-positive advanced or metastatic breast cancer, and in a PIK
    Ann Oncol. 2019;30:774-780.
    PubMed     Text format     Abstract available


  47. BACHELOT T, Ciruelos E, Schneeweiss A, Puglisi F, et al
    Preliminary safety and efficacy of first-line pertuzumab combined with trastuzumab and taxane therapy for HER2-positive locally recurrent or metastatic breast cancer (PERUSE).
    Ann Oncol. 2019;30:766-773.
    PubMed     Text format     Abstract available


    April 2019
  48. DE AZAMBUJA E, Piccart-Gebhart M
    ER+/HER2+ breast cancer: are we really de-escalating?
    Ann Oncol. 2019 Apr 16. pii: 5472336. doi: 10.1093.
    PubMed     Text format    


  49. MATIKAS A, Foukakis T, Swain S, Bergh J, et al
    Avoiding over- and undertreatment in patients with resected node-positive breast cancer with the use of gene expression signatures: are we there yet?
    Ann Oncol. 2019 Apr 9. pii: 5435960. doi: 10.1093.
    PubMed     Text format     Abstract available


  50. MARRA A, Curigliano G
    T cell Bispecific Antibodies to Bypass MHC Class I Loss in Breast Cancer.
    Ann Oncol. 2019 Apr 2. pii: 5425459. doi: 10.1093.
    PubMed     Text format    


  51. DELALOGE S, Cella D, Ye Y, Buyse M, et al
    Effects of neratinib on health-related quality of life in women with HER2-positive early-stage breast cancer: longitudinal analyses from the randomized phase III ExteNET trial.
    Ann Oncol. 2019;30:567-574.
    PubMed     Text format     Abstract available


  52. ROBSON ME, Tung N, Conte P, Im SA, et al
    OlympiAD final overall survival and tolerability results: Olaparib versus chemotherapy treatment of physician's choice in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer.
    Ann Oncol. 2019;30:558-566.
    PubMed     Text format     Abstract available


    March 2019
  53. DIOSSY M, Reiniger L, Sztupinszki Z, Krzystanek M, et al
    Corrigendum to: Breast cancer brain metastases show increased levels of genomic aberration-based homologous recombination deficiency scores relative to their corresponding primary tumors.
    Ann Oncol. 2019 Mar 30. pii: 5423828. doi: 10.1093.
    PubMed     Text format    


  54. MESSAOUDENE M, Mourikis TP, Michels J, Fu Y, et al
    T cell Bispecific Antibodies in Node-Positive Breast Cancer: Novel Therapeutic Avenue for MHC class I Loss Variants.
    Ann Oncol. 2019 Mar 29. pii: 5423181. doi: 10.1093.
    PubMed     Text format     Abstract available


  55. VEERARAGHAVAN J, De Angelis C, Mao R, Wang T, et al
    A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2+ breast cancer.
    Ann Oncol. 2019 Mar 23. pii: 5418530. doi: 10.1093.
    PubMed     Text format     Abstract available


  56. MALVEZZI M, Carioli G, Bertuccio P, Boffetta P, et al
    European cancer mortality predictions for the year 2019 with focus on breast cancer.
    Ann Oncol. 2019 Mar 19. pii: 5382368. doi: 10.1093.
    PubMed     Text format     Abstract available


  57. HREBIEN S, Citi V, Garcia-Murillas I, Cutts R, et al
    Early ctDNA dynamics as a surrogate for progression free survival in advanced breast cancer in the BEECH trial.
    Ann Oncol. 2019 Mar 12. pii: 5376514. doi: 10.1093.
    PubMed     Text format     Abstract available


  58. TURNER NC, Alarcon E, Armstrong AC, Philco M, et al
    BEECH: A dose-finding run-in followed by a randomised phase 2 study assessing the efficacy of AKT inhibitor capivasertib (AZD5363) combined with paclitaxel in patients with oestrogen receptor-positive advanced or metastatic breast cancer, and in a PIK
    Ann Oncol. 2019 Mar 12. pii: 5376517. doi: 10.1093.
    PubMed     Text format     Abstract available


    February 2019
  59. BACHELOT T, Ciruelos E, Schneeweiss A, Puglisi F, et al
    Preliminary safety and efficacy of first-line pertuzumab combined with trastuzumab and taxane therapy for HER2-positive locally recurrent or metastatic breast cancer (PERUSE).
    Ann Oncol. 2019 Feb 23. pii: 5364015. doi: 10.1093.
    PubMed     Text format     Abstract available


  60. GUARNERI V, Dieci MV, Bisagni G, Frassoldati A, et al
    De-escalated therapy for HR+/HER2+ breast cancer patients with Ki67 response after 2 weeks letrozole: results of the PerELISA neoadjuvant study.
    Ann Oncol. 2019 Feb 18. pii: 5332974. doi: 10.1093.
    PubMed     Text format     Abstract available


  61. TELLI ML, Vinayak S
    Future of checkpoint blockade in triple-negative breast cancer: combination strategies to lead the way.
    Ann Oncol. 2019 Feb 7. pii: 5308591. doi: 10.1093.
    PubMed     Text format    


  62. YAP YS, Ho D, Ng RC, Chan CH, et al
    27PDetection of genomic alterations in breast cancer (BC) patients with paired plasma and tumour specimens.
    Ann Oncol. 2019;30.
    PubMed     Text format    


  63. SON S, Kim H, Shin I
    23PMatricellular protein CCN3/NOV regulates tumorigenesis in triple-negative breast cancer.
    Ann Oncol. 2019;30.
    PubMed     Text format    


  64. KIM H, Son S
    22PTherapeutic potential of connective tissue growth factor (CTGF) in triple-negative breast cancer.
    Ann Oncol. 2019;30.
    PubMed     Text format    


  65. LUEN SJ, Salgado R, Dieci MV, Vingiani A, et al
    Prognostic implications of residual disease tumor-infiltrating lymphocytes and residual cancer burden in triple-negative breast cancer patients after neoadjuvant chemotherapy.
    Ann Oncol. 2019;30:236-242.
    PubMed     Text format     Abstract available


    January 2019
  66. CONDORELLI R, Mosele F, Verret B, Bachelot T, et al
    Genomic alterations in breast cancer: Level of evidence for actionability according to ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).
    Ann Oncol. 2019 Jan 31. pii: 5305018. doi: 10.1093.
    PubMed     Text format     Abstract available


  67. ROBSON ME, Tung N, Conte P, Im SA, et al
    OlympiAD final overall survival and tolerability results: Olaparib versus chemotherapy treatment of physician's choice in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer.
    Ann Oncol. 2019 Jan 23. pii: 5299440. doi: 10.1093.
    PubMed     Text format     Abstract available


  68. DELALOGE S, Cella D, Ye Y, Buyse M, et al
    Effects of Neratinib on Health-Related Quality-of-Life in Women with HER2-Positive Early-Stage Breast Cancer: Longitudinal Analyses from the Randomized Phase III ExteNET Trial.
    Ann Oncol. 2019 Jan 23. pii: 5299438. doi: 10.1093.
    PubMed     Text format     Abstract available


  69. DIECI MV, Conte P, Bisagni G, Brandes AA, et al
    Association of tumor-infiltrating lymphocytes with distant disease-free survival in the ShortHER randomized adjuvant trial for patients with early HER2+ breast cancer.
    Ann Oncol. 2019 Jan 17. pii: 5290085. doi: 10.1093.
    PubMed     Text format     Abstract available


  70. CORTES J, Calvo V, Ramirez-Merino N, O'Shaughnessy J, et al
    Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis.
    Ann Oncol. 2019 Jan 9. pii: 5281258. doi: 10.1093.
    PubMed     Text format    


  71. BASELGA J, Manikhas A, Cortes J, Llombart A, et al
    Phase III trial of nonpegylated liposomal doxorubicin in combination with trastuzumab and paclitaxel in HER2-positive metastatic breast cancer.
    Ann Oncol. 2019 Jan 9. pii: 5281256. doi: 10.1093.
    PubMed     Text format    


  72. LOIBL S, Majewski I, Guarneri V, Nekljudova V, et al
    PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab.
    Ann Oncol. 2019 Jan 9. pii: 5281259. doi: 10.1093.
    PubMed     Text format    


  73. SWAIN SM, Schneeweiss A, Gianni L, Gao JJ, et al
    Incidence and management of diarrhea in patients with HER2-positive breast cancer treated with pertuzumab.
    Ann Oncol. 2019 Jan 9. pii: 5281263. doi: 10.1093.
    PubMed     Text format    


  74. CURIGLIANO G, Burstein HJ, P Winer E, Gnant M, et al
    De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017.
    Ann Oncol. 2019 Jan 9. pii: 5281261. doi: 10.1093.
    PubMed     Text format    


  75. WU Y, Amonkar MM, Sherrill BH, O'Shaughnessy J, et al
    Impact of lapatinib plus trastuzumab versus single-agent lapatinib on quality of life of patients with trastuzumab-refractory HER2+ metastatic breast cancer.
    Ann Oncol. 2019 Jan 9. pii: 5281255. doi: 10.1093.
    PubMed     Text format    


    December 2018
  76. LUEN SJ, Salgado R, Dieci MV, Vingiani A, et al
    Prognostic implications of residual disease tumor-infiltrating lymphocytes and residual cancer burden in triple negative breast cancer patients after neo-adjuvant chemotherapy.
    Ann Oncol. 2018 Dec 27. pii: 5262220. doi: 10.1093.
    PubMed     Text format     Abstract available


    November 2018
  77. ADAMS S, Schmid P, Rugo HS, Winer EP, et al
    Pembrolizumab Monotherapy for Previously Treated Metastatic Triple-Negative Breast Cancer: Cohort A of the Phase 2 KEYNOTE-086 Study.
    Ann Oncol. 2018 Nov 26. pii: 5209693. doi: 10.1093.
    PubMed     Text format     Abstract available


  78. ADAMS S, Loi S, Toppmeyer D, Cescon DW, et al
    Title: Pembrolizumab Monotherapy for Previously Untreated, PD-L1-Positive, Metastatic Triple-Negative Breast Cancer: Cohort B of the Phase 2 KEYNOTE-086 Study.
    Ann Oncol. 2018 Nov 26. pii: 5209695. doi: 10.1093.
    PubMed     Text format     Abstract available


  79. EVRON E, Ben-David AM, Goldberg H, Fried G, et al
    Prophylactic Irradiation to the Contralateral Breast for BRCA Mutation Carriers with Early Stage Breast Cancer.
    Ann Oncol. 2018 Nov 23. pii: 5200725. doi: 10.1093.
    PubMed     Text format     Abstract available


  80. SOKOL ES, Feng YX, Jin DX, Basudan A, et al
    Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer.
    Ann Oncol. 2018 Nov 13. pii: 5181087. doi: 10.1093.
    PubMed     Text format     Abstract available


  81. FOUKAKIS T
    Carboplatin in the neoadjuvant treatment of triple-negative breast cancer - ready for prime time?
    Ann Oncol. 2018 Nov 5. pii: 5160131. doi: 10.1093.
    PubMed     Text format    


    October 2018
  82. MATHEW A, Erqou S
    Can Estrogen Receptor Status Predict for Shorter Duration of Adjuvant Trastuzumab in Early-Stage Breast Cancer?
    Ann Oncol. 2018 Oct 24. pii: 5144112. doi: 10.1093.
    PubMed     Text format    


  83. MATIKAS A, Foukakis T, Moebus V, Greil R, et al
    Dose tailoring of adjuvant chemotherapy for breast cancer based on hematologic toxicities: Further results from the prospective PANTHER study with focus on obese patients.
    Ann Oncol. 2018 Oct 24. pii: 5144113. doi: 10.1093.
    PubMed     Text format     Abstract available


  84. KOK M, Winer E, Loi S
    Passion for Immune checkpoint blockade in triple negative breast cancer? Comment on the IMpassion130 study.
    Ann Oncol. 2018 Oct 23. pii: 5142540. doi: 10.1093.
    PubMed     Text format    


  85. COTTU P, D'Hondt V, Dureau S, Lerebours F, et al
    Letrozole and palbociclib versus chemotherapy as neoadjuvant therapy of high-risk luminal breast cancer.
    Ann Oncol. 2018 Oct 11. pii: 5126820. doi: 10.1093.
    PubMed     Text format     Abstract available


  86. BRANDAO M, Ignatiadis M
    CDK4/6 inhibitors as neoadjuvant treatment in breast cancer - what can we learn?
    Ann Oncol. 2018 Oct 10. pii: 5126228. doi: 10.1093.
    PubMed     Text format    


    September 2018
  87. SZEKELY B, Bossuyt V, Li X, Wali VB, et al
    Immunological differences between primary and metastatic breast cancer.
    Ann Oncol. 2018 Sep 10. pii: 5094494. doi: 10.1093.
    PubMed     Text format     Abstract available


    August 2018
  88. CHEN X, Li Y, Ouyang T, Li J, et al
    Associations between RAD51D germline mutations and breast cancer risk and survival in BRCA1/2-negative breast cancers.
    Ann Oncol. 2018 Aug 27. pii: 5079839. doi: 10.1093.
    PubMed     Text format     Abstract available


  89. ETTL J, Quek RGW, Lee KH, Rugo HS, et al
    Quality of life with talazoparib versus physician's choice of chemotherapy in patients with advanced breast cancer and germline BRCA1/2 mutation: patient-reported outcomes from the EMBRACA phase III trial.
    Ann Oncol. 2018 Aug 15. pii: 5074207. doi: 10.1093.
    PubMed     Text format     Abstract available


    July 2018
  90. CARDOSO F, Senkus E, Costa A, Papadopoulos E, et al
    4th ESO-ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4).
    Ann Oncol. 2018 Jul 19. pii: 5055519. doi: 10.1093.
    PubMed     Text format    


  91. ROBSON M
    Selecting patients with triple negative breast cancer for platinum-based therapy: we still haven't found what we're looking for.
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    June 2018
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    Different menopausal hormone regimens and risk of breast cancer.
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    Biomarker assessment of the CBCSG006 trial: A randomized phase III trial of cisplatin plus gemcitabine compared with paclitaxel plus gemcitabine as first-line therapy for patients with metastatic triple-negative breast cancer.
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    Trastuzumab versus observation for HER2 non amplified early breast cancer with Circulating Tumor Cells (EORTC 90091-10093, BIG 1-12, Treat CTC): A randomized phase 2 trial.
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    Palbociclib as single agent or in combination with the endocrine therapy received before disease progression for estrogen receptor-positive, HER2-negative metastatic breast cancer: TREnd trial.
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    May 2018
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    De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017.
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    Combined pathologic-genomic algorithm for early-stage breast cancer improves cost-effective use of the 21-gene recurrence score assay.
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    Should de-escalation of bone-targeting agents be standard of care for patients with bone metastases from breast cancer? A systematic review and meta-analysis.
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    April 2018
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    Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer.
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    PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab.
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  104. GEFFEN DB
    Should decisions on adding adjuvant chemotherapy in early stage ER positive breast cancer be based on gene expression testing or clinicopathologic factors or both?
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  105. CRUZ C, Castroviejo-Bermejo M, Gutierrez-Enriquez S, Llop-Guevara A, et al
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    February 2018
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    Open-label randomised phase III trial of vinflunine versus an alkylating agent in patients with heavily pretreated metastatic breast cancer.
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    Randomised phase III trial of vinflunine plus capecitabine versus capecitabine alone in patients with advanced breast cancer previously treated with an anthracycline and resistant to taxane.
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    January 2018
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    N0332 phase 2 trial of weekly irinotecan hydrochloride and docetaxel in refractory metastatic breast cancer: a North Central Cancer Treatment Group (NCCTG) Trial.
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    Unravelling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis.
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    Recurrent hyperactive ESR1 fusion proteins in endocrine therapy resistant breast cancer.
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    Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer.
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    Clinical Considerations of the Role of Palbociclib in the Management of Advanced Breast Cancer Patients With and Without Visceral Metastases.
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    Impact of homologous recombination deficiency biomarkers on outcomes in patients with triple-negative breast cancer treated with doxorubicin-based adjuvant chemotherapy (SWOG S9313).
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    BRCA 1 and 2 mutation status: the elephant in the room during oncofertility counseling for young breast cancer patients.
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    November 2017
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    Male Breast Cancer: Pink Ribbon Blues.
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    October 2017
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    September 2017
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    Stromal lymphocyte infiltration after neoadjuvant chemotherapy is associated with aggressive residual disease and lower disease-free survival in HER2-positive breast cancer.
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    Genomic alterations and radioresistance in breast cancer: an analysis of the ProfiLER protocol.
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    Stromal inflammation, necrosis and HER2 overexpression in ductal carcinoma in situ of the breast: another causality dilemma?
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    August 2017
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    Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer.
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    February 2017
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    The prevalence and clinical relevance of tumor-infiltrating lymphocytes (TILs) in ductal carcinoma in situ of the breast.
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    Characterizing CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy.
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