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  Breast Cancer

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Articles published in J Biol Chem

Retrieve available abstracts of 48 articles:
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Single Articles


    September 2025
  1. NANDI S, Mondal A, Sarkar I, Akram Ddoza Hazari MW, et al
    The Hypoxia-Induced Chromatin Reader ZMYND8 Drives HIF-Dependent Metabolic Rewiring in Breast Cancer.
    J Biol Chem. 2025 Sep 3:110680. doi: 10.1016/j.jbc.2025.110680.
    PubMed     Abstract available


  2. LI X, Chung YM, Patel M, Sharifi N, et al
    Correction: of HSD3B1 upregulation via LRH1 sustains estrogen receptor signaling and promotes endocrine resistance in breast cancer.
    J Biol Chem. 2025;301:110553.
    PubMed    


  3. ZHAO M, Yuan D, Wei M, Zhang J, et al
    FOXO1- mediated argininosuccinate lyase transcription inhibits ammonia metabolism and breast cancer cell metastasis.
    J Biol Chem. 2025 Sep 2:110677. doi: 10.1016/j.jbc.2025.110677.
    PubMed     Abstract available


    August 2025
  4. YOSHIOKA Y, Nosaka C, Ohishi T, Nakajima M, et al
    Loss of Angulin-1/LSR promotes vasculogenic mimicry and epithelial-mesenchymal transition in breast cancer.
    J Biol Chem. 2025 Aug 27:110635. doi: 10.1016/j.jbc.2025.110635.
    PubMed     Abstract available


  5. SONG H, Peng J, Niu Z, Liu X, et al
    A non-coding RNA circGNAI2 suppresses triple-negative breast cancer progression by sponging miR-454-3p to inhibit the VGLL4-STAT3 signaling.
    J Biol Chem. 2025 Aug 8:110577. doi: 10.1016/j.jbc.2025.110577.
    PubMed     Abstract available


  6. EL-SAWY L, Rubin JR, Broses L, Patsalis C, et al
    The molecular mechanism of ambrosin induced cytotoxicity of human breast cancer and bladder cancer cells.
    J Biol Chem. 2025 Aug 1:110531. doi: 10.1016/j.jbc.2025.110531.
    PubMed     Abstract available


    July 2025
  7. SCHUMACHER TJ, Gardner ZS, Rumbley J, Ronayne CT, et al
    Development of novel mitochondrial pyruvate carrier inhibitors for breast cancer treatment.
    J Biol Chem. 2025 Jul 16:110486. doi: 10.1016/j.jbc.2025.110486.
    PubMed     Abstract available


  8. PANDEY A, Jithin B, Mutnuru SA, Samaiya A, et al
    Identification of SRSF9 through pooled shRNA screening links BNIP3 splicing to autophagy and metabolic reprogramming in breast cancer.
    J Biol Chem. 2025 Jul 15:110482. doi: 10.1016/j.jbc.2025.110482.
    PubMed     Abstract available


  9. WOYCIEHOWSKY M, Larson P, Stephan AR, Dandridge SL, et al
    Systematic characterization of zinc in a series of breast cancer cell lines reveals significant changes in zinc homeostasis.
    J Biol Chem. 2025 Jul 2:110442. doi: 10.1016/j.jbc.2025.110442.
    PubMed     Abstract available


  10. KHARAT SS, Mishra AP, Sengodan SK, Dierman D, et al
    5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells.
    J Biol Chem. 2025;301:110393.
    PubMed     Abstract available


  11. SHI S, Li X, Alderman C, Wick L, et al
    Cryo-EM structures reveal the PP2A-B55alpha and Eya3 interaction that can be disrupted by a peptide inhibitor.
    J Biol Chem. 2025;301:110287.
    PubMed     Abstract available


  12. HAN AL, Vinod Paul K, Rao S, Brechbuhl HM, et al
    Estradiol (E2) concentration shapes the chromatin binding landscape of estrogen receptor alpha.
    J Biol Chem. 2025;301:108499.
    PubMed     Abstract available


    June 2025
  13. TANIHARA T, Yoshida Y, Ogino T, Terada Y, et al
    Microcurrent stimulation induces cell death in p53-mutant and 5-FU-resistant breast cancer.
    J Biol Chem. 2025 Jun 24:110414. doi: 10.1016/j.jbc.2025.110414.
    PubMed     Abstract available


  14. LI X, Chung YM, Patel M, Sharifi N, et al
    HSD3B1 Upregulation via LRH1 Sustains Estrogen Receptor Signaling and Promotes Endocrine Resistance in Breast Cancer.
    J Biol Chem. 2025 Jun 20:110405. doi: 10.1016/j.jbc.2025.110405.
    PubMed     Abstract available


  15. SHOARI A, Coban MA, Hockla A, Rezhdo A, et al
    Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions.
    J Biol Chem. 2025;301:110258.
    PubMed     Abstract available


    May 2025
  16. QIU Y, Luan G, Liu Y, He Y, et al
    The transcriptional regulator Sin3a activates CD44 and promotes collective luminal breast cancer cell migration.
    J Biol Chem. 2025 May 21:110264. doi: 10.1016/j.jbc.2025.110264.
    PubMed     Abstract available


  17. HANG Q, Li W, Guo J, Zuo S, et al
    Inhibitory effects of beta-galactoside alpha2,6-sialyltransferase 1 on the Hippo pathway in breast cancer cells.
    J Biol Chem. 2025 May 21:110266. doi: 10.1016/j.jbc.2025.110266.
    PubMed     Abstract available


  18. MAJMUDAR PR, Keri RA
    The neural stem cell gene PAFAH1B1 controls cell cycle progression, DNA integrity, and paclitaxel sensitivity of triple-negative breast cancer cells.
    J Biol Chem. 2025 May 14:110235. doi: 10.1016/j.jbc.2025.110235.
    PubMed     Abstract available


  19. ZHANG X, Zhuang M, Zhang H, Zhu Y, et al
    Melatonin-mediated cGAS-STING signal in senescent macrophages promote TNBC chemotherapy resistance and drive the SASP.
    J Biol Chem. 2025;301:108438.
    PubMed     Abstract available


    April 2025
  20. LINSTRA R, Stappenbelt C, Bakker FJ, Everts M, et al
    MYC controls STING levels to downregulate inflammatory signaling in breast cancer cells upon DNA damage.
    J Biol Chem. 2025 Apr 29:108560. doi: 10.1016/j.jbc.2025.108560.
    PubMed     Abstract available


  21. -M FAN TW, Yan J, Goncalves CFL, Islam JMM, et al
    Patient-derived organotypic tissue cultures as a platform to evaluate metabolic reprogramming in breast cancer patients.
    J Biol Chem. 2025 Apr 8:108495. doi: 10.1016/j.jbc.2025.108495.
    PubMed     Abstract available


  22. FAN TC, Yeo HL, Hung TH, Chang NC, et al
    ST3GAL1 regulates cancer cell migration through crosstalk between EGFR and neuropilin-1 signaling.
    J Biol Chem. 2025;301:108368.
    PubMed     Abstract available


    March 2025
  23. HU Y, Bian J, Chen W, Shi J, et al
    Androgen receptor-induced lncRNA SOX2-OT promotes triple-negative breast cancer tumorigenesis via targeting miR-320a-5p/CCR5 axis.
    J Biol Chem. 2025 Mar 19:108428. doi: 10.1016/j.jbc.2025.108428.
    PubMed     Abstract available


  24. SENDANAYAKE LR, Pokhrel R, Holub JM
    Surveying helix 12 dynamics within constitutively active estrogen receptors using bipartite tetracysteine display.
    J Biol Chem. 2025;301:108231.
    PubMed     Abstract available


    February 2025
  25. SONG X, Liu S, Zeng Y, Cai Y, et al
    BANCR-Containing Extracellular Vesicles Enhance Breast Cancer Resistance.
    J Biol Chem. 2025 Feb 11:108304. doi: 10.1016/j.jbc.2025.108304.
    PubMed     Abstract available


  26. BOBBITT JR, Cuellar-Vite L, Weber-Bonk KL, Yancey MR, et al
    Targeting the mitotic kinase NEK2 enhances CDK4/6 inhibitor efficacy by potentiating genome instability.
    J Biol Chem. 2025;301:108196.
    PubMed     Abstract available


    January 2025
  27. BAGCHI A, Bhattacharya A, Bera A, Basak D, et al
    PDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer.
    J Biol Chem. 2025 Jan 27:108239. doi: 10.1016/j.jbc.2025.108239.
    PubMed     Abstract available


  28. PAUL S, Chatterjee A, Das K, Ray A, et al
    Thrombin confers chemotherapeutic resistance by promoting transcriptional induction and post-translational stabilization of pro-survival MCL1 in TNBC.
    J Biol Chem. 2025;301:108025.
    PubMed     Abstract available


  29. MCDERMOTT N, O'Shea S, Rieger L, Cox OT, et al
    beta(1)-integrin controls IGF-1R internalization and intracellular signaling.
    J Biol Chem. 2025;301:108021.
    PubMed     Abstract available


    December 2024
  30. YU S, Si Y, Xu M, Wang Y, et al
    Downregulation of the splicing regulator NSRP1 confers resistance to CDK4/6 inhibitors via activation of interferon signaling in breast cancer.
    J Biol Chem. 2024 Dec 10:108070. doi: 10.1016/j.jbc.2024.108070.
    PubMed     Abstract available


  31. LETSON J, Ren G, Zheng X, Sweef O, et al
    Reduced S-nitrosylation of TGFbeta1 elevates its binding affinity toward the receptor and promotes fibrogenic signaling in the breast.
    J Biol Chem. 2024;300:108011.
    PubMed     Abstract available


  32. PAN KW, Chen HC
    Perinuclear assembly of vimentin intermediate filaments induces cancer cell nuclear dysmorphia.
    J Biol Chem. 2024;300:107981.
    PubMed     Abstract available


    November 2024
  33. MASSEY S, Kongchan N, Gao Y, Chaudhury A, et al
    PKC-mediated phosphorylation governs the stability and function of CELF1 as a driver of EMT in breast epithelial cells.
    J Biol Chem. 2024;300:107826.
    PubMed     Abstract available


    October 2024
  34. OROBATOR ON, Mertens RT, Obisesan OA, Awuah SG, et al
    Energy and endoplasmic reticulum stress induction by gold(III) dithiocarbamate and 2-deoxyglucose synergistically trigger cell death in breast cancer.
    J Biol Chem. 2024 Oct 29:107949. doi: 10.1016/j.jbc.2024.107949.
    PubMed     Abstract available


  35. SAUNDERS H, Holloran S, Trinca G, Artigues A, et al
    Site specific O-GlcNAcylation of progesterone receptor (PR) supports PR attenuation of interferon stimulated genes (ISGs) and tumor growth in breast cancer.
    J Biol Chem. 2024 Oct 10:107886. doi: 10.1016/j.jbc.2024.107886.
    PubMed     Abstract available


  36. ROTENBERG N, Feldman M, Shirian J, Hockla A, et al
    Engineered TIMP2 with narrow MMP-9 specificity is an effective inhibitor of invasion and proliferation of triple negative breast cancer cells.
    J Biol Chem. 2024 Oct 9:107867. doi: 10.1016/j.jbc.2024.107867.
    PubMed     Abstract available


  37. THI K, Del Toro K, Licon-Munoz Y, Sayaman RW, et al
    Comprehensive identification, isolation, and culture of human breast cell types.
    J Biol Chem. 2024;300:107637.
    PubMed     Abstract available


    September 2024
  38. BERNA-ERRO A, Lopez JJ, Jardin I, Sanchez-Collado J, et al
    Differential functional role of Orai1 variants in constitutive Ca(2+) entry and calcification in luminal breast cancer cells.
    J Biol Chem. 2024 Sep 18:107786. doi: 10.1016/j.jbc.2024.107786.
    PubMed     Abstract available


  39. ZHANG J, Chen Y, Gong X, Yang Y, et al
    GATA factor TRPS1, a new DNA repair protein, cooperates with reversible PARylation to promote chemoresistance in breast cancer patients.
    J Biol Chem. 2024 Sep 12:107780. doi: 10.1016/j.jbc.2024.107780.
    PubMed     Abstract available


  40. CHEN X, Li D, Su Q, Ling X, et al
    SENP3 mediates the deSUMOylation and degradation of YAP1 to regulate the progression of triple-negative breast cancer.
    J Biol Chem. 2024 Sep 11:107764. doi: 10.1016/j.jbc.2024.107764.
    PubMed     Abstract available


  41. QIAN T, Bai F, Zhang S, Xu Y, et al
    USP11 deubiquitinates E-cadherin and maintains luminal fate of mammary tumor cells to suppress breast cancer.
    J Biol Chem. 2024 Sep 11:107768. doi: 10.1016/j.jbc.2024.107768.
    PubMed     Abstract available


    August 2024
  42. TANG K, Yin T, Deng B, Wang M, et al
    USP7 deubiquitinates epigenetic reader ZMYND8 to promote breast cancer cell migration and invasion.
    J Biol Chem. 2024 Aug 9:107672. doi: 10.1016/j.jbc.2024.107672.
    PubMed     Abstract available


    July 2024
  43. PERRON T, Boissan M, Bieche I, Courtois L, et al
    CYYR1 promotes the degradation of the E3 ubiquitin ligase WWP1 and is associated with favorable prognosis in breast cancer.
    J Biol Chem. 2024 Jul 24:107601. doi: 10.1016/j.jbc.2024.107601.
    PubMed     Abstract available


    June 2024
  44. GUO Q, Zhao J, Li Y, Zhang C, et al
    CK2-HTATSF1-TOPBP1 signaling axis modulates tumor chemotherapy response.
    J Biol Chem. 2024;300:107377.
    PubMed     Abstract available


    May 2024
  45. PANDEY A, Kakani P, Shukla S
    CTCF and BORIS-mediated Autophagy regulation via Alternative splicing of BNIP3L in Breast Cancer.
    J Biol Chem. 2024 May 27:107416. doi: 10.1016/j.jbc.2024.107416.
    PubMed     Abstract available


  46. DUAN L, Tadi MJ, O'Hara KM, Maki CG, et al
    Novel markers of MCL1 inhibitor sensitivity in triple negative breast cancer cells.
    J Biol Chem. 2024 May 16:107375. doi: 10.1016/j.jbc.2024.107375.
    PubMed     Abstract available


    April 2024
  47. YANG P, Li Y, Hou J, Wu D, et al
    Blockade of a novel MAP4K4-LATS2-SASH1-YAP1 cascade inhibits tumorigenesis and metastasis in luminal breast cancer.
    J Biol Chem. 2024 Apr 22:107309. doi: 10.1016/j.jbc.2024.107309.
    PubMed     Abstract available


  48. GOEL HL, Karner ER, Kumar A, Mukhopadhyay D, et al
    YAP/TAZ-mediated regulation of laminin 332 is enabled by beta4 integrin repression of ZEB1 to promote ferroptosis resistance.
    J Biol Chem. 2024;300:107202.
    PubMed     Abstract available


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