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  Breast Cancer

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Articles published in J Biol Chem

Retrieve available abstracts of 47 articles:
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Single Articles


    July 2020
  1. LI K, Liu T, Chen J, Ni H, et al
    Survivin in breast cancer-derived exosomes activates fibroblasts by upregulating SOD1, whose feedback promotes cancer proliferation and metastasis.
    J Biol Chem. 2020 Jul 24. pii: RA120.013805. doi: 10.1074/jbc.RA120.013805.
    PubMed     Abstract available


  2. ZHANG P, Yang Y, Qian K, Li L, et al
    A novel tumor suppressor ZBTB1 regulates tamoxifen resistance and aerobic glycolysis through suppressing HER2 expression in breast cancer.
    J Biol Chem. 2020 Jul 20. pii: RA119.010759. doi: 10.1074/jbc.RA119.010759.
    PubMed     Abstract available


    June 2020

  3. Expression of Concern: Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
    J Biol Chem. 2020;295:8886.
    PubMed    



  4. Expression of Concern: Bone marrow stromal cell-derived growth inhibitor inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis.
    J Biol Chem. 2020;295:8876.
    PubMed    


  5. SEACHRIST DD, Hannigan MM, Ingles NN, Webb BM, et al
    --The transcriptional repressor BCL11A promotes breast cancer metastasis.
    J Biol Chem. 2020 Jun 23. pii: RA120.014018. doi: 10.1074/jbc.RA120.014018.
    PubMed     Abstract available


    May 2020
  6. GASPARYAN M, Lo MC, Jiang H, Lin CC, et al
    Combined P53/PTEN deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer.
    J Biol Chem. 2020 May 28. pii: RA119.010710. doi: 10.1074/jbc.RA119.010710.
    PubMed     Abstract available


  7. SWEENEY C
    Targeting the polyamine pathway-"a means" to overcome chemoresistance in triple-negative breast cancer.
    J Biol Chem. 2020;295:6278-6279.
    PubMed     Abstract available


    March 2020
  8. GECK RC, Foley JR, Murray Stewart T, Asara JM, et al
    Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
    J Biol Chem. 2020 Mar 5. pii: RA119.012376. doi: 10.1074/jbc.RA119.012376.
    PubMed     Abstract available


    January 2020
  9. FARRINGTON CC, Yuan E, Mazhar S, Izadmehr S, et al
    Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers.
    J Biol Chem. 2020;295:757-770.
    PubMed     Abstract available


  10. SUBBARAMAIAH K, Hudis C, Chang SH, Hla T, et al
    Withdrawal: EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells: Evidence of a BRCA1 and p300 exchange.
    J Biol Chem. 2020;295:295.
    PubMed    


    November 2019
  11. NIU J, Shi Y, Tan G, Yang CH, et al
    Withdrawal: DNA damage induces NF-kappaB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion.
    J Biol Chem. 2019;294:18015.
    PubMed    


    October 2019
  12. MISHRA J, Simonsen R, Kumar N
    Intestinal breast cancer resistance protein (BCRP) requires Janus kinase 3 activity for drug efflux and barrier functions in obesity.
    J Biol Chem. 2019 Oct 25. pii: RA119.007758. doi: 10.1074/jbc.RA119.007758.
    PubMed     Abstract available


  13. WU Y, Qin J, Li F, Yang C, et al
    USP3 promotes breast cancer cell proliferation by deubiquitinating KLF5.
    J Biol Chem. 2019 Oct 17. pii: RA119.009102. doi: 10.1074/jbc.RA119.009102.
    PubMed     Abstract available


    August 2019
  14. SOMYAJIT K, Subramanya S, Nagaraju G
    Correction: Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: Implications for Fanconi anemia and breast cancer susceptibility.
    J Biol Chem. 2019;294:13198.
    PubMed    


    July 2019
  15. DAS K, Paul S, Singh A, Ghosh A, et al
    Triple negative breast cancer-derived microvesicles transfer microRNA221 to the recipient cells and thereby promote epithelial-to-mesenchymal transition.
    J Biol Chem. 2019 Jul 24. pii: RA119.008619. doi: 10.1074/jbc.RA119.008619.
    PubMed     Abstract available


    June 2019
  16. MCGUIRE CM, Collins MP, Sun-Wada G, Wada Y, et al
    Isoform-specific gene disruptions reveal a role for the V-ATPase subunit a4 isoform in the invasiveness of 4T1-12B breast cancer cells.
    J Biol Chem. 2019 Jun 5. pii: RA119.007713. doi: 10.1074/jbc.RA119.007713.
    PubMed     Abstract available


  17. STONE JK, Kim JH, Vukadin L, Richard A, et al
    Hypoxia induces cancer cell-specific chromatin interactions and increases MALAT1 expression in breast cancer cells.
    J Biol Chem. 2019 Jun 5. pii: RA118.006889. doi: 10.1074/jbc.RA118.006889.
    PubMed     Abstract available


    April 2019
  18. REIS LMD, Adamoski D, Oliveira Souza RO, Rodrigues Ascencao CF, et al
    Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition-resistant triple-negative breast cancer cells.
    J Biol Chem. 2019 Apr 30. pii: RA119.008180. doi: 10.1074/jbc.RA119.008180.
    PubMed     Abstract available


  19. FERNANDES VC, Golubeva VA, Di Pietro G, Shields C, et al
    Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation.
    J Biol Chem. 2019;294:5980-5992.
    PubMed     Abstract available


  20. CHEN MK, Du Y, Sun L, Hsu JL, et al
    H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bounded retrograde trafficking mechanism.
    J Biol Chem. 2019 Apr 8. pii: RA118.005953. doi: 10.1074/jbc.RA118.005953.
    PubMed     Abstract available


  21. EISA NH, Jilani Y, Kainth K, Redd P, et al
    The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis.
    J Biol Chem. 2019;294:5246-5260.
    PubMed     Abstract available


    March 2019
  22. BORINI ETICHETTI C, Di Benedetto C, Rossi C, Baglioni MV, et al
    Isoprenylcysteine carboxy methyltransferase (ICMT) is associated with tumor aggressiveness and its expression is controlled by the p53 tumor suppressor.
    J Biol Chem. 2019;294:5060-5073.
    PubMed     Abstract available


  23. BROER A, Gauthier-Coles G, Rahimi F, van Geldermalsen M, et al
    Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells.
    J Biol Chem. 2019;294:4012-4026.
    PubMed     Abstract available


  24. BRAGANZA A, Quesnelle K, Bickta J, Reyes C, et al
    Myoglobin induces mitochondrial fusion thereby inhibiting breast cancer cell proliferation.
    J Biol Chem. 2019 Mar 14. pii: RA118.006673. doi: 10.1074/jbc.RA118.006673.
    PubMed     Abstract available


  25. DAS A, Narayanam MK, Paul S, Mukherjee P, et al
    A novel triazole NMK-T-057 induces autophagic cell death in breast cancer cells by inhibiting gamma-secretase-mediated activation of Notch-signaling.
    J Biol Chem. 2019 Mar 1. pii: RA119.007671. doi: 10.1074/jbc.RA119.007671.
    PubMed     Abstract available


    February 2019
  26. CUESTA R, Berman AY, Alayev A, Holz MK, et al
    Estrogen receptor alpha promotes protein synthesis by fine-tuning the expression of the eukaryotic translation initiation factor 3 subunit f (eIF3f).
    J Biol Chem. 2019;294:2267-2278.
    PubMed     Abstract available


    January 2019
  27. TUROWEC JP, Lau EWT, Wang X, Brown KR, et al
    Functional genomic characterization of a synthetic anti-HER3 antibody reveals a role for ubiquitination by RNF41 in the anti-proliferative response.
    J Biol Chem. 2019;294:1396-1409.
    PubMed     Abstract available


    December 2018
  28. AGGARWAL S, Gabrovsek L, Langeberg LK, Golkowski M, et al
    Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility.
    J Biol Chem. 2018 Dec 31. pii: RA118.006741. doi: 10.1074/jbc.RA118.006741.
    PubMed     Abstract available


    November 2018
  29. GAYLE SS, Sahni JM, Webb BM, Weber-Bonk KL, et al
    Targeting BCL-xL improves the efficacy of bromodomain and extra-terminal protein inhibitors in triple-negative breast cancer by eliciting the death of senescent cells.
    J Biol Chem. 2018 Nov 27. pii: RA118.004712. doi: 10.1074/jbc.RA118.004712.
    PubMed     Abstract available


  30. JEONG J, Choi J, Kim W, Dann P, et al
    Inhibition of ezrin causes PKCalpha-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells.
    J Biol Chem. 2018 Nov 21. pii: RA118.004143. doi: 10.1074/jbc.RA118.004143.
    PubMed     Abstract available


  31. LI Z, Lim SK, Liang X, Lim YP, et al
    The transcriptional coactivator WBP2 primes triple-negative breast cancer cells for responses to Wnt signaling via the JNK/Jun kinase pathway.
    J Biol Chem. 2018 Nov 15. pii: RA118.005796. doi: 10.1074/jbc.RA118.005796.
    PubMed     Abstract available


  32. BRIXIUS-ANDERKO S, Scott EE
    Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design.
    J Biol Chem. 2018 Nov 13. pii: RA118.006214. doi: 10.1074/jbc.RA118.006214.
    PubMed     Abstract available


  33. SUBBARAMAIAH K, Iyengar NM, Morrow M, Elemento O, et al
    Prostaglandin E2down-regulates sirtuin 1 (SIRT1) leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.
    J Biol Chem. 2018 Nov 8. pii: RA118.005866. doi: 10.1074/jbc.RA118.005866.
    PubMed     Abstract available


    October 2018
  34. GODBOLE M, Togar T, Patel K, Dharavath B, et al
    Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells.
    J Biol Chem. 2018 Oct 18. pii: RA118.002894. doi: 10.1074/jbc.RA118.002894.
    PubMed     Abstract available


    August 2018
  35. TEGOWSKI M, Fan C, Baldwin AS
    Thioridazine inhibits self-renewal in breast cancer cells via DRD2-dependent STAT3 inhibition, but induces a G1 arrest independent of DRD2.
    J Biol Chem. 2018 Aug 21. pii: RA118.003719. doi: 10.1074/jbc.RA118.003719.
    PubMed     Abstract available


    May 2018
  36. YAN T, Zhang A, Shi F, Chang F, et al
    Integrin alphavbeta3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
    J Biol Chem. 2018 May 11. pii: RA117.000327. doi: 10.1074/jbc.RA117.000327.
    PubMed     Abstract available


    April 2018
  37. KARTHIK IP, Desai P, Sukumar S, Dimitrijevic A, et al
    E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases.
    J Biol Chem. 2018;293:5624-5635.
    PubMed     Abstract available


    March 2018
  38. ITOU J, Li W, Ito S, Tanaka S, et al
    Sal-like 4 protein levels in breast cancer cells are post-translationally down-regulated by tripartite motif containing 21.
    J Biol Chem. 2018 Mar 6. pii: RA117.000245. doi: 10.1074/jbc.RA117.000245.
    PubMed     Abstract available


    February 2018
  39. MAPES J, Anandan L, Li Q, Neff A, et al
    Aberrantly high expression of the CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in mammary epithelium leads to breast tumorigenesis.
    J Biol Chem. 2018;293:2850-2864.
    PubMed     Abstract available


  40. SUN X, Gupta K, Wu B, Zhang D, et al
    Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice.
    J Biol Chem. 2018;293:2841-2849.
    PubMed     Abstract available


  41. MOODY RR, Lo MC, Meagher JL, Lin CC, et al
    Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.
    J Biol Chem. 2018;293:2125-2136.
    PubMed     Abstract available


    December 2017
  42. CARDEN T, Singh B, Mooga V, Bajpai P, et al
    Epigenetic modification of miR-663 controls mitochondria-to-nucleus retrograde signaling and tumor progression.
    J Biol Chem. 2017;292:20694-20706.
    PubMed     Abstract available


  43. WANG D, Liu C, Wang J, Jia Y, et al
    Protein C receptor stimulates multiple signaling pathways in breast cancer cells.
    J Biol Chem. 2017 Dec 7. pii: M117.814046. doi: 10.1074/jbc.M117.814046.
    PubMed     Abstract available


    November 2017
  44. NADANAKA S, Kinouchi H, Kitagawa H
    Chondroitin sulfates-mediated N-cadherin/beta-catenin signaling is associated with basal-like breast cancer cell invasion.
    J Biol Chem. 2017 Nov 28. pii: M117.814509. doi: 10.1074/jbc.M117.814509.
    PubMed     Abstract available


  45. MCFALL T, McKnight B, Rosati R, Kim S, et al
    Progesterone Receptor A Promotes Invasiveness and Metastasis of Luminal Breast Cancer by Suppressing Regulation of Critical Micro RNAs by Estrogen.
    J Biol Chem. 2017 Nov 21. pii: jbc.M117.812438. doi: 10.1074/jbc.M117.812438.
    PubMed     Abstract available


  46. WOODCOCK CC, Huang Y, Woodcock SR, Salvatore SR, et al
    Nitro-fatty acid inhibition of triple negative breast cancer cell viability, migration, invasion and tumor growth.
    J Biol Chem. 2017 Nov 20. pii: jbc.M117.814368. doi: 10.1074/jbc.M117.814368.
    PubMed     Abstract available


    October 2017
  47. DELIGIO JT, Lin G, Chalfant CE, Park MA, et al
    Splice variants of cytosolic polyadenylation element-binding protein 2 (CPEB2) differentially regulate pathways linked to cancer metastasis.
    J Biol Chem. 2017;292:17909-17918.
    PubMed     Abstract available


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