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Articles published in J Clin Invest

Retrieve available abstracts of 32 articles:
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Single Articles


    January 2021
  1. DERSH D, Yewdell JW
    Immune MAL2-practice: breast cancer immunoevasion via MHC class I degradation.
    J Clin Invest. 2021;131.
    PubMed     Abstract available


    December 2020
  2. EDWARDS DN, Ngwa VM, Raybuck AL, Wang S, et al
    Selective glutamine metabolism inhibition in tumor cells improves anti-tumor T lymphocyte activity in triple-negative breast cancer.
    J Clin Invest. 2020 Dec 15. pii: 140100. doi: 10.1172/JCI140100.
    PubMed     Abstract available


    September 2020
  3. FANG Y, Wang L, Wan C, Sun Y, et al
    MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation.
    J Clin Invest. 2020 Sep 29. pii: 140837. doi: 10.1172/JCI140837.
    PubMed     Abstract available


  4. SONG K, Cai X, Dong Y, Wu H, et al
    Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
    J Clin Invest. 2020 Sep 22. pii: 129374. doi: 10.1172/JCI129374.
    PubMed     Abstract available


  5. DE HEER EC, Jalving M, Harris AL
    HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer.
    J Clin Invest. 2020 Sep 1. pii: 137552. doi: 10.1172/JCI137552.
    PubMed     Abstract available


    July 2020
  6. NORTHEY JJ, Barrett AS, Acerbi I, Hayward MK, et al
    Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
    J Clin Invest. 2020 Jul 28. pii: 129249. doi: 10.1172/JCI129249.
    PubMed     Abstract available


  7. PAUL MR, Pan TC, Pant DK, Shih NN, et al
    Genomic landscape of metastatic breast cancer identifies preferentially dysregulated pathways and targets.
    J Clin Invest. 2020 Jul 13. pii: 129941. doi: 10.1172/JCI129941.
    PubMed     Abstract available


    June 2020
  8. GARCIA-RECIO S, Thennavan A, East MP, Parker JS, et al
    FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease.
    J Clin Invest. 2020 Jun 23. pii: 130323. doi: 10.1172/JCI130323.
    PubMed     Abstract available


  9. LIU J, Zhang C, Wu H, Sun XX, et al
    Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression.
    J Clin Invest. 2020;130:3253-3269.
    PubMed     Abstract available


    May 2020
  10. LU H, Xie Y, Tran L, Lan J, et al
    Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness.
    J Clin Invest. 2020 May 19. pii: 138577. doi: 10.1172/JCI138577.
    PubMed     Abstract available


  11. ZARRIZI R, Higgs MR, Vossgrone K, Rossing M, et al
    Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability.
    J Clin Invest. 2020 May 7. pii: 127521. doi: 10.1172/JCI127521.
    PubMed     Abstract available


    March 2020
  12. GAGLIANO T, Shah K, Gargani S, Lao L, et al
    PIK3Cdelta expression by fibroblasts promotes triple-negative breast cancer progression.
    J Clin Invest. 2020 Mar 3. pii: 128313. doi: 10.1172/JCI128313.
    PubMed     Abstract available


    January 2020
  13. CHANDLER BC, Moubadder L, Ritter CL, Liu M, et al
    TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination.
    J Clin Invest. 2020 Jan 21. pii: 130435. doi: 10.1172/JCI130435.
    PubMed     Abstract available


    November 2019
  14. RISOM T, Wang X, Liang J, Zhang X, et al
    Deregulating MYC in a model of HER2+ breast cancer mimics human intertumoral heterogeneity.
    J Clin Invest. 2019 Nov 25. pii: 126390. doi: 10.1172/JCI126390.
    PubMed     Abstract available


    July 2019
  15. PRIMAC I, Maquoi E, Blacher S, Heljasvaara R, et al
    Stromal integrin alpha11 regulates PDGFR-beta signaling and promotes breast cancer progression.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    June 2019
  16. KOHRT HE, Houot R, Weiskopf K, Goldstein MJ, et al
    Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer.
    J Clin Invest. 2019;129:2595.
    PubMed    


    January 2019
  17. CUI B, Luo Y, Tian P, Peng F, et al
    Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells.
    J Clin Invest. 2019 Jan 28. pii: 121685. doi: 10.1172/JCI121685.
    PubMed     Abstract available


    November 2018
  18. JOHMURA Y, Maeda I, Suzuki N, Wu W, et al
    Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.
    J Clin Invest. 2018 Nov 12. pii: 121679. doi: 10.1172/JCI121679.
    PubMed     Abstract available


    October 2018
  19. CHERNIKOVA SB, Nguyen RB, Truong JT, Mello SS, et al
    Dynamin impacts homology-directed repair and breast cancer response to chemotherapy.
    J Clin Invest. 2018 Oct 29. pii: 87191. doi: 10.1172/JCI87191.
    PubMed     Abstract available


  20. KUMAR S, Wilkes DW, Samuel N, Blanco MA, et al
    DeltaNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer.
    J Clin Invest. 2018 Oct 8. pii: 99673. doi: 10.1172/JCI99673.
    PubMed     Abstract available


    September 2018
  21. WANG Y, Weng X, Wang L, Hao M, et al
    HIC1 deletion promotes breast cancer progression by activating tumor cell/fibroblast crosstalk.
    J Clin Invest. 2018 Sep 11. pii: 99974. doi: 10.1172/JCI99974.
    PubMed     Abstract available


    August 2018
  22. MABE NW, Fox DB, Lupo R, Decker AE, et al
    Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer.
    J Clin Invest. 2018 Aug 27. pii: 99481. doi: 10.1172/JCI99481.
    PubMed     Abstract available


    April 2018
  23. YU J, Qin B, Moyer AM, Nowsheen S, et al
    DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine.
    J Clin Invest. 2018 Apr 30. pii: 97924. doi: 10.1172/JCI97924.
    PubMed     Abstract available


  24. CHEN Y, Zhang B, Bao L, Jin L, et al
    ZMYND8 acetylation mediates HIF-dependent breast cancer progression and metastasis.
    J Clin Invest. 2018 Apr 9. pii: 95089. doi: 10.1172/JCI95089.
    PubMed     Abstract available


    March 2018
  25. BAO L, Qian Z, Lyng MB, Wang L, et al
    Coexisting genomic aberrations associated with lymph node metastasis in breast cancer.
    J Clin Invest. 2018 Mar 15. pii: 97449. doi: 10.1172/JCI97449.
    PubMed     Abstract available


    February 2018
  26. SIEGEL MB, He X, Hoadley KA, Hoyle A, et al
    Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer.
    J Clin Invest. 2018 Feb 26. pii: 96153. doi: 10.1172/JCI96153.
    PubMed     Abstract available


  27. ZHAO N, Cao J, Xu L, Tang Q, et al
    Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
    J Clin Invest. 2018 Feb 26. pii: 95873. doi: 10.1172/JCI95873.
    PubMed     Abstract available


  28. ULLAH I, Karthik GM, Alkodsi A, Kjallquist U, et al
    Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes.
    J Clin Invest. 2018 Feb 26. pii: 96149. doi: 10.1172/JCI96149.
    PubMed     Abstract available


    December 2017
  29. SUN Q, Lesperance J, Wettersten H, Luterstein E, et al
    Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.
    J Clin Invest. 2017 Dec 11. pii: 93707. doi: 10.1172/JCI93707.
    PubMed     Abstract available


    November 2017
  30. MISHRA P, Tang W, Putluri V, Dorsey TH, et al
    ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming.
    J Clin Invest. 2017 Nov 27. pii: 93815. doi: 10.1172/JCI93815.
    PubMed     Abstract available


  31. WANG S, Liang K, Hu Q, Li P, et al
    JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.
    J Clin Invest. 2017 Nov 13. pii: 91553. doi: 10.1172/JCI91553.
    PubMed     Abstract available


    August 2017
  32. JESCHKE J, Bizet M, Desmedt C, Calonne E, et al
    DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.
    J Clin Invest. 2017;127:3090-3102.
    PubMed     Abstract available


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