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Articles published in Oncogene

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    January 2022
  1. AVALLE L, Raggi L, Monteleone E, Savino A, et al
    STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts.
    Oncogene. 2022 Jan 18. pii: 10.1038/s41388-021-02172.
    PubMed     Abstract available


  2. LIU Y, Ma L, Hua F, Min Z, et al
    Exosomal circCARM1 from spheroids reprograms cell metabolism by regulating PFKFB2 in breast cancer.
    Oncogene. 2022 Jan 13. pii: 10.1038/s41388-021-02061.
    PubMed     Abstract available


  3. SHU L, Chen A, Li L, Yao L, et al
    NRG1 regulates Fra-1 transcription and metastasis of triple-negative breast cancer cells via the c-Myc ubiquitination as manipulated by ERK1/2-mediated Fbxw7 phosphorylation.
    Oncogene. 2022 Jan 7. pii: 10.1038/s41388-021-02142.
    PubMed     Abstract available


    December 2021
  4. ZHANG S, Guo X, Liu X, Zhong Z, et al
    Correction to: Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation.
    Oncogene. 2021 Dec 20. pii: 10.1038/s41388-021-02129.
    PubMed    


  5. CAO X, Geradts J, Dewhirst MW, Lo HW, et al
    Correction: Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
    Oncogene. 2021 Dec 9. pii: 10.1038/s41388-021-02043.
    PubMed    


    November 2021
  6. KONG Y, Zhang Y, Wang H, Kan W, et al
    Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFbeta signaling.
    Oncogene. 2021 Nov 19. pii: 10.1038/s41388-021-02098.
    PubMed     Abstract available


  7. LI Y, Liu HT, Chen X, Wang YW, et al
    Aberrant promoter hypermethylation inhibits RGMA expression and contributes to tumor progression in breast cancer.
    Oncogene. 2021 Nov 9. pii: 10.1038/s41388-021-02083.
    PubMed     Abstract available


  8. RUIZ-TORRES SJ, Bourn JR, Benight NM, Hunt BG, et al
    Macrophage-mediated RON signaling supports breast cancer growth and progression through modulation of IL-35.
    Oncogene. 2021 Nov 6. pii: 10.1038/s41388-021-02091.
    PubMed     Abstract available


  9. YI B, Wang S, Wang X, Liu Z, et al
    CRISPR interference and activation of the microRNA-3662-HBP1 axis control progression of triple-negative breast cancer.
    Oncogene. 2021 Nov 2. pii: 10.1038/s41388-021-02089.
    PubMed     Abstract available


  10. ROUKENS MG, Frederiks CL, Seinstra D, Braccioli L, et al
    Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation.
    Oncogene. 2021;40:6343-6353.
    PubMed     Abstract available


  11. BOLADO-CARRANCIO A, Lee M, Ewing A, Muir M, et al
    ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling.
    Oncogene. 2021;40:6235-6247.
    PubMed     Abstract available


    October 2021
  12. TANG SC, Lion Q, Peulen O, Chariot P, et al
    The E3 ligase COP1 promotes ERalpha signaling and suppresses EMT in breast cancer.
    Oncogene. 2021 Oct 29. pii: 10.1038/s41388-021-02038.
    PubMed     Abstract available


  13. CHERADAME L, Guerrera IC, Gaston J, Schmitt A, et al
    STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway.
    Oncogene. 2021 Oct 8. pii: 10.1038/s41388-021-02037.
    PubMed     Abstract available


  14. BLOCK CJ, Mitchell AV, Wu L, Glassbrook J, et al
    RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA.
    Oncogene. 2021 Oct 4. pii: 10.1038/s41388-021-02030.
    PubMed     Abstract available


    September 2021
  15. LIU Z, Sang X, Wang M, Liu Y, et al
    Melatonin potentiates the cytotoxic effect of Neratinib in HER2(+) breast cancer through promoting endocytosis and lysosomal degradation of HER2.
    Oncogene. 2021 Sep 23. pii: 10.1038/s41388-021-02015.
    PubMed     Abstract available


  16. VAFAIZADEH V, Buechel D, Rubinstein N, Kalathur RKR, et al
    The interactions of Bcl9/Bcl9L with beta-catenin and Pygopus promote breast cancer growth, invasion, and metastasis.
    Oncogene. 2021 Sep 20. pii: 10.1038/s41388-021-02016.
    PubMed     Abstract available


  17. PALMA FR, Ratti BA, Paviani V, Coelho DR, et al
    AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism.
    Oncogene. 2021;40:5455-5467.
    PubMed     Abstract available


    August 2021
  18. SUN J, Gaidosh G, Xu Y, Mookhtiar A, et al
    RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells.
    Oncogene. 2021 Aug 9. pii: 10.1038/s41388-021-01985.
    PubMed     Abstract available


  19. ZHANG F, Li P, Liu S, Yang M, et al
    beta-Catenin-CCL2 feedback loop mediates crosstalk between cancer cells and macrophages that regulates breast cancer stem cells.
    Oncogene. 2021 Aug 3. pii: 10.1038/s41388-021-01986.
    PubMed     Abstract available


  20. YAN Y, Narayan A, Cho S, Cheng Z, et al
    CRYbetaB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer.
    Oncogene. 2021 Aug 2. pii: 10.1038/s41388-021-01975.
    PubMed     Abstract available


  21. MAJHI PD, Griner NB, Mayfield JA, Compton S, et al
    Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome.
    Oncogene. 2021;40:5026-5037.
    PubMed     Abstract available


    July 2021
  22. ZHANG S, Guo X, Liu X, Zhong Z, et al
    Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation.
    Oncogene. 2021 Jul 30. pii: 10.1038/s41388-021-01970.
    PubMed     Abstract available


  23. WHATELY KM, Voronkova MA, Maskey A, Gandhi J, et al
    Nuclear Aurora-A kinase-induced hypoxia signaling drives early dissemination and metastasis in breast cancer: implications for detection of metastatic tumors.
    Oncogene. 2021 Jul 29. pii: 10.1038/s41388-021-01969.
    PubMed     Abstract available


  24. SETO-TETSUO F, Arioka M, Miura K, Inoue T, et al
    DIF-1 inhibits growth and metastasis of triple-negative breast cancer through AMPK-mediated inhibition of the mTORC1-S6K signaling pathway.
    Oncogene. 2021 Jul 24. pii: 10.1038/s41388-021-01958.
    PubMed     Abstract available


  25. ZHANG Y, Shi G, Zhang H, Xiong Q, et al
    Dexamethasone enhances the lung metastasis of breast cancer via a PI3K-SGK1-CTGF pathway.
    Oncogene. 2021 Jul 16. pii: 10.1038/s41388-021-01944.
    PubMed     Abstract available


  26. CLEMENTS ME, Holtslander L, Edwards C, Todd V, et al
    HDAC inhibitors induce LIFR expression and promote a dormancy phenotype in breast cancer.
    Oncogene. 2021 Jul 10. pii: 10.1038/s41388-021-01931.
    PubMed     Abstract available


  27. YU P, Zhu X, Zhu JL, Han YB, et al
    The Chk2-PKM2 axis promotes metabolic control of vasculogenic mimicry formation in p53-mutated triple-negative breast cancer.
    Oncogene. 2021 Jul 9. pii: 10.1038/s41388-021-01933.
    PubMed     Abstract available


  28. HAMALIAN S, Guth R, Runa F, Sanchez F, et al
    A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling markers.
    Oncogene. 2021 Jul 8. pii: 10.1038/s41388-021-01906.
    PubMed     Abstract available


  29. ZHANG J, Liu Y, Tan J, Zhang Y, et al
    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC.
    Oncogene. 2021;40:4783-4795.
    PubMed     Abstract available


  30. ZHAO Z, Guo Y, Liu Y, Sun L, et al
    Individualized lncRNA differential expression profile reveals heterogeneity of breast cancer.
    Oncogene. 2021;40:4604-4614.
    PubMed     Abstract available


  31. LIU X, Li L, Si F, Huang L, et al
    NK and NKT cells have distinct properties and functions in cancer.
    Oncogene. 2021;40:4521-4537.
    PubMed     Abstract available


    June 2021
  32. QIU Y, Yang Y, Yang R, Liu C, et al
    Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer.
    Oncogene. 2021 Jun 25. pii: 10.1038/s41388-021-01896.
    PubMed     Abstract available


  33. BI X, Lou P, Song Y, Sheng X, et al
    Msi1 promotes breast cancer metastasis by regulating invadopodia-mediated extracellular matrix degradation via the Timp3-Mmp9 pathway.
    Oncogene. 2021 Jun 21. pii: 10.1038/s41388-021-01873.
    PubMed     Abstract available


  34. SHARIATI M, Evans KW, Zheng X, Bristow CA, et al
    Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations.
    Oncogene. 2021 Jun 9. pii: 10.1038/s41388-021-01819.
    PubMed     Abstract available


  35. TRUONG TH, Benner EA, Hagen KM, Temiz NA, et al
    PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER(+) breast cancer.
    Oncogene. 2021 Jun 8. pii: 10.1038/s41388-021-01871.
    PubMed     Abstract available


  36. QIAO Y, Jin T, Guan S, Cheng S, et al
    Long non-coding RNA Lnc-408 promotes invasion and metastasis of breast cancer cell by regulating LIMK1.
    Oncogene. 2021 Jun 2. pii: 10.1038/s41388-021-01845.
    PubMed     Abstract available


  37. PROKAKIS E, Dyas A, Grun R, Fritzsche S, et al
    USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response.
    Oncogene. 2021;40:4004-4018.
    PubMed     Abstract available


    May 2021
  38. LODILLINSKY C, Fuhrmann L, Irondelle M, Pylypenko O, et al
    Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
    Oncogene. 2021 May 19. pii: 10.1038/s41388-021-01826.
    PubMed     Abstract available


  39. XU Q, Zhang J, Telfer BA, Zhang H, et al
    The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion.
    Oncogene. 2021 May 12. pii: 10.1038/s41388-021-01798.
    PubMed     Abstract available


  40. LAGER TW, Conner C, Keating CR, Warshaw JN, et al
    Cell surface GRP78 and Dermcidin cooperate to regulate breast cancer cell migration through Wnt signaling.
    Oncogene. 2021 May 12. pii: 10.1038/s41388-021-01821.
    PubMed     Abstract available


  41. WILLIAMS CB, Phelps-Polirer K, Dingle IP, Williams CJ, et al
    Correction: HUNK phosphorylates EGFR to regulate breast cancer metastasis.
    Oncogene. 2021 May 6. pii: 10.1038/s41388-021-01797.
    PubMed    


  42. STEBBING J, Zhang H, Xu Y, Lit LC, et al
    Correction: KSR1 regulates BRCA1 degradation and inhibits breast cancer growth.
    Oncogene. 2021 May 4. pii: 10.1038/s41388-021-01794.
    PubMed    


    April 2021
  43. LIU L, Zhang X, Ding H, Liu X, et al
    Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS.
    Oncogene. 2021 Apr 29. pii: 10.1038/s41388-021-01785.
    PubMed     Abstract available


  44. STEBBING J, Zhang H, Xu Y, Lit LC, et al
    Correction to: KSR1 regulates BRCA1 degradation and inhibits breast cancer growth.
    Oncogene. 2021 Apr 22. pii: 10.1038/s41388-021-01759.
    PubMed    


  45. TRAPHAGEN NA, Hosford SR, Jiang A, Marotti JD, et al
    High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer.
    Oncogene. 2021 Apr 19. pii: 10.1038/s41388-021-01782.
    PubMed     Abstract available


  46. KIM ES, Nam SM, Song HK, Lee S, et al
    CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity.
    Oncogene. 2021 Apr 8. pii: 10.1038/s41388-021-01758.
    PubMed     Abstract available


  47. MAI J, Peng XD, Tang J, Du T, et al
    AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation.
    Oncogene. 2021;40:2422-2436.
    PubMed     Abstract available


    March 2021
  48. LIANG Y, Song X, Li Y, Su P, et al
    Correction: circKDM4C suppresses tumor progression and attenuates doxorubicin resistance by regulating miR-548p/PBLD axis in breast cancer.
    Oncogene. 2021 Mar 25. pii: 10.1038/s41388-021-01750.
    PubMed    


  49. WANG X, Feng M, Xiao T, Guo B, et al
    BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.
    Oncogene. 2021 Mar 25. pii: 10.1038/s41388-021-01756.
    PubMed     Abstract available


  50. HUTCHINSON SA, Websdale A, Cioccoloni G, Roberg-Larsen H, et al
    Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer.
    Oncogene. 2021 Mar 19. pii: 10.1038/s41388-021-01720.
    PubMed     Abstract available


  51. WANG YH, Chan YT, Hung TH, Hung JT, et al
    Transmembrane and coiled-coil domain family 3 (TMCC3) regulates breast cancer stem cell and AKT activation.
    Oncogene. 2021 Mar 19. pii: 10.1038/s41388-021-01729.
    PubMed     Abstract available


  52. MARTINEZ-ORDONEZ A, Seoane S, Avila L, Eiro N, et al
    POU1F1 transcription factor induces metabolic reprogramming and breast cancer progression via LDHA regulation.
    Oncogene. 2021 Mar 13. pii: 10.1038/s41388-021-01740.
    PubMed     Abstract available


  53. CHEN T, Wang X, Li C, Zhang H, et al
    CircHIF1A regulated by FUS accelerates triple-negative breast cancer progression by modulating NFIB expression and translocation.
    Oncogene. 2021 Mar 13. pii: 10.1038/s41388-021-01739.
    PubMed     Abstract available


  54. KIM H, Son S, Ko Y, Shin I, et al
    CTGF regulates cell proliferation, migration, and glucose metabolism through activation of FAK signaling in triple-negative breast cancer.
    Oncogene. 2021 Mar 10. pii: 10.1038/s41388-021-01731.
    PubMed     Abstract available


  55. BERDIEL-ACER M, Maia A, Hristova Z, Borgoni S, et al
    Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts.
    Oncogene. 2021 Mar 10. pii: 10.1038/s41388-021-01719.
    PubMed     Abstract available


  56. JALALIRAD M, Haddad TC, Salisbury JL, Radisky D, et al
    Aurora-A kinase oncogenic signaling mediates TGF-beta-induced triple-negative breast cancer plasticity and chemoresistance.
    Oncogene. 2021 Mar 5. pii: 10.1038/s41388-021-01711.
    PubMed     Abstract available


  57. REINSBOROUGH CW, Ipas H, Abell NS, Gouws EB, et al
    BCDIN3D RNA methyltransferase stimulates Aldolase C expression and glycolysis through let-7 microRNA in breast cancer cells.
    Oncogene. 2021 Mar 4. pii: 10.1038/s41388-021-01702.
    PubMed     Abstract available


  58. SIRKISOON SR, Carpenter RL, Rimkus T, Doheny D, et al
    Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.
    Oncogene. 2021 Mar 2. pii: 10.1038/s41388-020-01620.
    PubMed    


  59. GE LP, Jin X, Yang YS, Liu XY, et al
    Tektin4 loss promotes triple-negative breast cancer metastasis through HDAC6-mediated tubulin deacetylation and increases sensitivity to HDAC6 inhibitor.
    Oncogene. 2021 Mar 2. pii: 10.1038/s41388-021-01655.
    PubMed     Abstract available


  60. VARONE E, Decio A, Chernorudskiy A, Minoli L, et al
    The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions.
    Oncogene. 2021;40:1721-1736.
    PubMed     Abstract available


  61. AHMED SF, Buetow L, Gabrielsen M, Lilla S, et al
    E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK-CBL-CIN85 axis.
    Oncogene. 2021;40:2149-2164.
    PubMed     Abstract available


  62. LIN CC, Yang WH, Lin YT, Tang X, et al
    DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway.
    Oncogene. 2021;40:2018-2034.
    PubMed     Abstract available


  63. YE Z, Wang D, Lu Y, He Y, et al
    Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZbeta.
    Oncogene. 2021;40:1775-1791.
    PubMed     Abstract available


    February 2021
  64. WU R, Li K, Yuan M, Luo KQ, et al
    Nerve growth factor receptor increases the tumor growth and metastatic potential of triple-negative breast cancer cells.
    Oncogene. 2021 Feb 24. pii: 10.1038/s41388-021-01691.
    PubMed     Abstract available


  65. BUTTI R, Nimma R, Kundu G, Bulbule A, et al
    Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression.
    Oncogene. 2021 Feb 18. pii: 10.1038/s41388-021-01663.
    PubMed     Abstract available


  66. WANG G, Wang J, Chang A, Cheng D, et al
    Correction to: Her2 promotes early dissemination of breast cancer by suppressing the p38 pathway through Skp2-mediated proteasomal degradation of Tpl2.
    Oncogene. 2021 Feb 10. pii: 10.1038/s41388-021-01652.
    PubMed    


  67. KUNG CP, Cottrell KA, Ryu S, Bramel ER, et al
    Correction to: Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer.
    Oncogene. 2021 Feb 9. pii: 10.1038/s41388-021-01669.
    PubMed    


  68. PAN JK, Lin CH, Kuo YL, Ger LP, et al
    MiR-211 determines brain metastasis specificity through SOX11/NGN2 axis in triple-negative breast cancer.
    Oncogene. 2021 Feb 3. pii: 10.1038/s41388-021-01654.
    PubMed     Abstract available


  69. CHEN D, Parker TM, Bhat-Nakshatri P, Chu X, et al
    Nonlinear relationship between chromatin accessibility and estradiol-regulated gene expression.
    Oncogene. 2021;40:1332-1346.
    PubMed     Abstract available


  70. AL-AKHRASS H, Conway JRW, Poulsen ASA, Paatero I, et al
    A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance.
    Oncogene. 2021;40:1300-1317.
    PubMed     Abstract available


  71. GU G, Tian L, Herzog SK, Rechoum Y, et al
    Hormonal modulation of ESR1 mutant metastasis.
    Oncogene. 2021;40:997-1011.
    PubMed     Abstract available


    January 2021
  72. ABRIL YLN, Fernandez IR, Hong JY, Chiang YL, et al
    Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer.
    Oncogene. 2021 Jan 21. pii: 10.1038/s41388-020-01637.
    PubMed     Abstract available


  73. ZHU P, He F, Hou Y, Tu G, et al
    A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability.
    Oncogene. 2021 Jan 19. pii: 10.1038/s41388-020-01638.
    PubMed     Abstract available


  74. ZHANG H, Wong CCL, Wei H, Gilkes DM, et al
    Correction: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs.
    Oncogene. 2021 Jan 15. pii: 10.1038/s41388-020-01618.
    PubMed    


  75. VARESLIJA D, Ward E, Purcell SP, Cosgrove NS, et al
    Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype.
    Oncogene. 2021 Jan 8. pii: 10.1038/s41388-020-01606.
    PubMed     Abstract available


  76. PANTANO F, Croset M, Driouch K, Bednarz-Knoll N, et al
    Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions.
    Oncogene. 2021 Jan 8. pii: 10.1038/s41388-020-01603.
    PubMed     Abstract available


  77. YOUSEFI H, Vatanmakanian M, Mahdiannasser M, Mashouri L, et al
    Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance.
    Oncogene. 2021 Jan 8. pii: 10.1038/s41388-020-01588.
    PubMed     Abstract available


  78. TIEDE S, Kalathur RKR, Luond F, von Allmen L, et al
    Multi-color clonal tracking reveals intra-stage proliferative heterogeneity during mammary tumor progression.
    Oncogene. 2021;40:12-27.
    PubMed     Abstract available


    December 2020
  79. KONG D, Zhou H, Neelakantan D, Hughes CJ, et al
    VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk.
    Oncogene. 2020 Dec 9. pii: 10.1038/s41388-020-01539.
    PubMed     Abstract available


  80. HAN J, Qu H, Han M, Ding Y, et al
    MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer.
    Oncogene. 2020 Dec 3. pii: 10.1038/s41388-020-01574.
    PubMed     Abstract available


  81. SONG Y, Zeng S, Zheng G, Chen D, et al
    FOXO3a-driven miRNA signatures suppresses VEGF-A/NRP1 signaling and breast cancer metastasis.
    Oncogene. 2020 Dec 1. pii: 10.1038/s41388-020-01562.
    PubMed     Abstract available


    November 2020
  82. ATTALLA S, Taifour T, Bui T, Muller W, et al
    Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo.
    Oncogene. 2020 Nov 24. pii: 10.1038/s41388-020-01560.
    PubMed     Abstract available


  83. GUAN X, Deng H, Choi UL, Li Z, et al
    EZH2 overexpression dampens tumor-suppressive signals via an EGR1 silencer to drive breast tumorigenesis.
    Oncogene. 2020;39:7127-7141.
    PubMed     Abstract available


    October 2020
  84. ABDULLAH A, Akhand SS, Paez JSP, Brown W, et al
    Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer.
    Oncogene. 2020 Oct 30. pii: 10.1038/s41388-020-01530.
    PubMed     Abstract available


  85. KUNG CP, Cottrell KA, Ryu S, Bramel ER, et al
    Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer.
    Oncogene. 2020 Oct 27. pii: 10.1038/s41388-020-01515.
    PubMed     Abstract available


  86. ZHENG X, Lu S, He Z, Huang H, et al
    MCU-dependent negative sorting of miR-4488 to extracellular vesicles enhances angiogenesis and promotes breast cancer metastatic colonization.
    Oncogene. 2020 Oct 16. pii: 10.1038/s41388-020-01514.
    PubMed     Abstract available


  87. LI Y, Li L, Qin J, Wu J, et al
    OSR1 phosphorylates the Smad2/3 linker region and induces TGF-beta1 autocrine to promote EMT and metastasis in breast cancer.
    Oncogene. 2020 Oct 13. pii: 10.1038/s41388-020-01499.
    PubMed     Abstract available


  88. ZHANG L, Qin Y, Wu G, Wang J, et al
    PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1.
    Oncogene. 2020 Oct 9. pii: 10.1038/s41388-020-01494.
    PubMed     Abstract available


  89. CHEN H, Libring S, Ruddraraju KV, Miao J, et al
    SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer.
    Oncogene. 2020 Oct 8. pii: 10.1038/s41388-020-01488.
    PubMed     Abstract available


  90. WANG S, Somisetty VS, Bai B, Chernukhin I, et al
    The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen.
    Oncogene. 2020;39:6300-6312.
    PubMed     Abstract available


    September 2020
  91. WANG G, Wang J, Chang A, Cheng D, et al
    Her2 promotes early dissemination of breast cancer by suppressing the p38 pathway through Skp2-mediated proteasomal degradation of Tpl2.
    Oncogene. 2020 Sep 28. pii: 10.1038/s41388-020-01481.
    PubMed     Abstract available


  92. ZHU J, Li X, Su P, Xue M, et al
    The ubiquitin ligase RNF181 stabilizes ERalpha and modulates breast cancer progression.
    Oncogene. 2020 Sep 24. pii: 10.1038/s41388-020-01464.
    PubMed     Abstract available


  93. LI LY, Chen XS, Wang KS, Guan YD, et al
    RSK2 protects human breast cancer cells under endoplasmic reticulum stress through activating AMPKalpha2-mediated autophagy.
    Oncogene. 2020 Sep 21. pii: 10.1038/s41388-020-01447.
    PubMed     Abstract available


    August 2020
  94. WANG M, Long K, Li E, Li L, et al
    DNA polymerase beta modulates cancer progression via enhancing CDH13 expression by promoter demethylation.
    Oncogene. 2020;39:5507-5519.
    PubMed     Abstract available


    July 2020
  95. CHAI TF, Manu KA, Casey PJ, Wang M, et al
    Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal.
    Oncogene. 2020;39:5373-5389.
    PubMed     Abstract available


    June 2020
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    Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities.
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    April 2020
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  100. JEANNOT E, Darrigues L, Michel M, Stern MH, et al
    A single droplet digital PCR for ESR1 activating mutations detection in plasma.
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    March 2020
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    C3a elicits unique migratory responses in immature low-density neutrophils.
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    CCR2 signaling in breast carcinoma cells promotes tumor growth and invasion by promoting CCL2 and suppressing CD154 effects on the angiogenic and immune microenvironments.
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    February 2020
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    Initiation of human mammary cell tumorigenesis by mutant KRAS requires YAP inactivation.
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