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  Biliary Tract Diseases

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Articles published in Gut

Retrieve available abstracts of 56 articles:
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Single Articles


    September 2025
  1. MENDONCA PROENCA I, Lera Dos Santos ME, Maluf-Filho F
    Biliary sludge and microlithiasis: are we covering the full spectrum of lithogenic biliary disorders?
    Gut. 2025 Sep 19:gutjnl-2025-336609. doi: 10.1136/gutjnl-2025-336609.
    PubMed    


  2. AHMED W, Haworth E, Sharp L, Dobson C, et al
    Endoscopic Retrograde Cholangiopancreatography (ERCP) services across the UK.
    Gut. 2025 Sep 10:gutjnl-2025-335548. doi: 10.1136/gutjnl-2025-335548.
    PubMed    


    August 2025
  3. MILARDI G, Franceschini B, Camisaschi C, Puccio S, et al
    Immunosuppressive contribution of tumour-infiltrating B cells in human intrahepatic cholangiocarcinoma and their role in chemoimmunotherapy outcome.
    Gut. 2025 Aug 31:gutjnl-2025-334861. doi: 10.1136/gutjnl-2025-334861.
    PubMed     Abstract available


  4. KONINGS B, Balsiger LM, Hreinsson JP, Simren M, et al
    Global prevalence and gastrointestinal symptom burden of individuals with a history of cholecystectomy.
    Gut. 2025 Aug 12:gutjnl-2024-334531. doi: 10.1136/gutjnl-2024-334531.
    PubMed     Abstract available


  5. MERCADO-GOMEZ M, Goikoetxea-Usandizaga N, Gine AE, Merlos Rodrigo MA, et al
    Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential.
    Gut. 2025 Aug 5:gutjnl-2024-333255. doi: 10.1136/gutjnl-2024-333255.
    PubMed     Abstract available


  6. VILLA E
    CNNM4: a ferroptotic vulnerability in cholangiocarcinoma.
    Gut. 2025 Aug 5:gutjnl-2025-335061. doi: 10.1136/gutjnl-2025-335061.
    PubMed    


    July 2025
  7. LIU F, Chen W, Zhang Z, Zeng W, et al
    Targeting Aurora kinase B regulates cholesterol metabolism and enhances chemoimmunotherapy in cholangiocarcinoma.
    Gut. 2025 Jul 31:gutjnl-2025-335291. doi: 10.1136/gutjnl-2025-335291.
    PubMed     Abstract available


  8. BANNON CA, Walters JRF, Wu T, Kay RG, et al
    Insulin-like peptide 5 is released in response to bile acid in the rectum and is associated with diarrhoea severity in patients with bile acid diarrhoea.
    Gut. 2025 Jul 23:gutjnl-2025-335393. doi: 10.1136/gutjnl-2025-335393.
    PubMed     Abstract available


  9. MORALI K, Vicent S
    To be or not to be (a biliary cancer): RAS (signalling) is the question.
    Gut. 2025 Jul 15:gutjnl-2025-335690. doi: 10.1136/gutjnl-2025-335690.
    PubMed    


    June 2025
  10. LOU C, Lan T, Xu S, Hu X, et al
    Heterogeneity and plasticity of cholangiocytes in liver injury: a journey from pathophysiology to therapeutic utility.
    Gut. 2025 Jun 9:gutjnl-2025-334763. doi: 10.1136/gutjnl-2025-334763.
    PubMed     Abstract available


  11. ZHU C, Boucheron N, Al-Rubaye O, Chung BK, et al
    24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting T(H)17 pathogenicity and transdifferentiation.
    Gut. 2025;74:1079-1093.
    PubMed     Abstract available


  12. ZHANG W, Tao L, Wang F, Shao B, et al
    Endoscopic mucosal resection in the pancreatobiliary system under direct cholangiopancreatoscopic guidance.
    Gut. 2025 Jun 6:gutjnl-2025-335707. doi: 10.1136/gutjnl-2025-335707.
    PubMed    


    May 2025
  13. LI P, Lei Q, Yu X, Shen Y, et al
    Commensal Bacteroides T6SS alleviate GI-aGVHD via mediating gut microbiota composition and bile acids metabolism.
    Gut. 2025 May 28:gutjnl-2024-334565. doi: 10.1136/gutjnl-2024-334565.
    PubMed     Abstract available


  14. ROSNER T, Rupp C, Lechler C, Bauer U, et al
    Activation of RAS/MEK/ERK signalling drives biliary differentiation in primary liver cancer.
    Gut. 2025 May 12:gutjnl-2024-333238. doi: 10.1136/gutjnl-2024-333238.
    PubMed     Abstract available


  15. HE Y, Kostallari E
    When getting reactive becomes the nORM: the emerging roles of proinflammatory cholangiokines.
    Gut. 2025 May 7:gutjnl-2025-335426. doi: 10.1136/gutjnl-2025-335426.
    PubMed    


    April 2025
  16. LIU H, Yin G, Franco Leonardi B, Lan T, et al
    Reactive cholangiocyte-derived ORM2 drives a pathogenic modulation of the injured biliary niche through macrophage reprogramming.
    Gut. 2025 Apr 8:gutjnl-2024-334425. doi: 10.1136/gutjnl-2024-334425.
    PubMed     Abstract available


  17. ZHURAVLEVA E, Lewinska M, O'Rourke CJ, Pea A, et al
    Mutational signatures define immune and Wnt-associated subtypes of ampullary carcinoma.
    Gut. 2025;74:804-814.
    PubMed     Abstract available


    March 2025
  18. TAN L, Wu WKK
    24-Nor-ursodeoxycholic acid: a novel treatment targeting T-cell-mediated immune dysregulation in primary sclerosing cholangitis and beyond.
    Gut. 2025 Mar 26:gutjnl-2025-334966. doi: 10.1136/gutjnl-2025-334966.
    PubMed    


    February 2025
  19. BANG JY, Faraj Agha M, Hawes R, Varadarajulu S, et al
    Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction.
    Gut. 2025 Feb 26:gutjnl-2025-334979. doi: 10.1136/gutjnl-2025-334979.
    PubMed    


    December 2024
  20. LIM Y, Kang S, Shah A, Holtmann G, et al
    Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?
    Gut. 2024 Dec 20:gutjnl-2024-334069. doi: 10.1136/gutjnl-2024-334069.
    PubMed    


  21. HOLLENBACH M, Heise C, Abou-Ali E, Gulla A, et al
    Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis.
    Gut. 2024 Dec 12:gutjnl-2022-327996. doi: 10.1136/gutjnl-2022-327996.
    PubMed     Abstract available


  22. DESERT R, Goyal L, Baumert TF
    Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment.
    Gut. 2024 Dec 6:gutjnl-2024-333632. doi: 10.1136/gutjnl-2024-333632.
    PubMed    


    October 2024
  23. ONNEKINK AM, Gorris M, Bekkali NL, Bos P, et al
    Endoscopic sphincterotomy to prevent post-ERCP pancreatitis after self-expandable metal stent placement for distal malignant biliary obstruction (SPHINX): a multicentre, randomised controlled trial.
    Gut. 2024 Oct 10:gutjnl-2024-332695. doi: 10.1136/gutjnl-2024-332695.
    PubMed     Abstract available


    September 2024
  24. ELURBIDE J, Colyn L, Latasa MU, Uriarte I, et al
    Identification of PRMT5 as a therapeutic target in cholangiocarcinoma.
    Gut. 2024 Sep 11:gutjnl-2024-332998. doi: 10.1136/gutjnl-2024-332998.
    PubMed     Abstract available


  25. COTE GA, Elmunzer BJ, Nitchie H, Kwon RS, et al
    Sphincterotomy for biliary sphincter of Oddi disorder and idiopathic acute recurrent pancreatitis: the RESPOnD longitudinal cohort.
    Gut. 2024 Sep 7:gutjnl-2024-332686. doi: 10.1136/gutjnl-2024-332686.
    PubMed     Abstract available


    August 2024
  26. SHI C, Hong J, Bai B, Li S, et al
    Morphological consistency between EUS and ERCP in diagnosing biliary sludge and microlithiasis.
    Gut. 2024 Aug 22:gutjnl-2024-332971. doi: 10.1136/gutjnl-2024-332971.
    PubMed    


  27. KHAN SA, Rushbrook SM, Kendall TJ, Zen Y, et al
    Guidelines Development Group for the British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma.
    Gut. 2024 Aug 19:gutjnl-2024-333359. doi: 10.1136/gutjnl-2024-333359.
    PubMed    


    July 2024
  28. HOV JR
    Sclerosing cholangitis and inflammatory bowel disease: a paradoxical relationship?
    Gut. 2024 Jul 17:gutjnl-2024-332835. doi: 10.1136/gutjnl-2024-332835.
    PubMed    


    June 2024
  29. KEGGENHOFF FL, Castven D, Becker D, Stojkovic S, et al
    PARP-1 selectively impairs KRAS-driven phenotypic and molecular features in intrahepatic cholangiocarcinoma.
    Gut. 2024 Jun 10:gutjnl-2023-331237. doi: 10.1136/gutjnl-2023-331237.
    PubMed     Abstract available


  30. BEDKE T, Stumme F, Tomczak M, Steglich B, et al
    Protective function of sclerosing cholangitis on IBD.
    Gut. 2024 Jun 5:gutjnl-2023-330856. doi: 10.1136/gutjnl-2023-330856.
    PubMed     Abstract available


    May 2024
  31. HE H, Chen S, Yu Y, Fan Z, et al
    Comprehensive single-cell analysis deciphered microenvironmental dynamics and immune regulator olfactomedin 4 in pathogenesis of gallbladder cancer.
    Gut. 2024 May 6:gutjnl-2023-331773. doi: 10.1136/gutjnl-2023-331773.
    PubMed     Abstract available


    April 2024

  32. Correction: Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers.
    Gut. 2024 Apr 23:gutjnl-2016-312278corr1. doi: 10.1136/gutjnl-2016-312278.
    PubMed    


  33. FABRIS L, Pol J
    Mast cells and histamine in cholangiocarcinoma: exploring overlooked avenues for enhanced patient management.
    Gut. 2024 Apr 18:gutjnl-2024-332288. doi: 10.1136/gutjnl-2024-332288.
    PubMed    


  34. BANG JY, Arnoletti JP, Wagner A, Varadarajulu S, et al
    EUS-guided gallbladder drainage in acute cholecystitis: response to letter to the editor.
    Gut. 2024 Apr 12:gutjnl-2024-332342. doi: 10.1136/gutjnl-2024-332342.
    PubMed    


    March 2024
  35. HAYLER R, Tuft C, Fisher O
    Head of pancreas mass with biliary obstruction: an unusual cause.
    Gut. 2024 Mar 22:gutjnl-2024-332268. doi: 10.1136/gutjnl-2024-332268.
    PubMed    


  36. LARGHI A, van Wanrooij RLJ, Bronswijk M, Vanella G, et al
    Cholecystectomy following EUS-guided gallbladder drainage in patients with acute cholecystitis at high surgical risk: friend or foe?
    Gut. 2024 Mar 22:gutjnl-2024-332273. doi: 10.1136/gutjnl-2024-332273.
    PubMed    


  37. SHI A, Liu Z, Fan Z, Li K, et al
    Function of mast cell and bile-cholangiocarcinoma interplay in cholangiocarcinoma microenvironment.
    Gut. 2024 Mar 8:gutjnl-2023-331715. doi: 10.1136/gutjnl-2023-331715.
    PubMed     Abstract available


    January 2024
  38. TOTH R, Brindley PJ, Vaquero J
    Enhancing the opportunities for cholangiocarcinoma precision therapy.
    Gut. 2024 Jan 16:gutjnl-2023-331480. doi: 10.1136/gutjnl-2023-331480.
    PubMed    


    December 2023
  39. HANNEMANN A, Mayerle J, Beyer G
    Response to: Correspondence on 'Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: still needed further discussion' by Wang et al.
    Gut. 2023 Dec 2:gutjnl-2023-331525. doi: 10.1136/gutjnl-2023-331525.
    PubMed    


    November 2023
  40. BANG JY, Arnoletti JP, Wagner A, Varadarajulu S, et al
    EUS-guided gallbladder drainage in acute cholecystitis: long-term problems with surgical approach.
    Gut. 2023 Nov 24:gutjnl-2023-331245. doi: 10.1136/gutjnl-2023-331245.
    PubMed    


  41. HONG JH, Yong CH, Heng HL, Chan JY, et al
    Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies.
    Gut. 2023 Nov 24:gutjnl-2023-330483. doi: 10.1136/gutjnl-2023-330483.
    PubMed     Abstract available


  42. FRITZSCHE JA, Smit E, Ponsioen CY, Voermans RP, et al
    Time to focus on the real potential benefit of endobiliary radiofrequency ablation: stent patency in patients with cholangiocarcinoma.
    Gut. 2023 Nov 21:gutjnl-2023-331359. doi: 10.1136/gutjnl-2023-331359.
    PubMed    


  43. CHEN L, Qiu W, Sun X, Gao M, et al
    Novel insights into causal effects of serum lipids and lipid-modifying targets on cholelithiasis.
    Gut. 2023 Nov 9:gutjnl-2023-330784. doi: 10.1136/gutjnl-2023-330784.
    PubMed     Abstract available


  44. NAKAGAMI S, Morita T, Yazumi S
    Rare cause of obstructive jaundice.
    Gut. 2023 Nov 6:gutjnl-2023-330496. doi: 10.1136/gutjnl-2023-330496.
    PubMed    


    October 2023
  45. ARECHEDERRA M, Casadei Gardini A, Raggi C
    More than shots in the dark: improving patient stratification to move closer to personalised therapies in intrahepatic cholangiocarcinoma.
    Gut. 2023 Oct 27:gutjnl-2023-331119. doi: 10.1136/gutjnl-2023-331119.
    PubMed    


  46. WANG F, Peng L, Liu Y
    Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: still needed further discussion.
    Gut. 2023 Oct 10:gutjnl-2023-331163. doi: 10.1136/gutjnl-2023-331163.
    PubMed    


  47. LI JS, Fang J, Li ZS
    Endoluminal radiofrequency ablation prior to stenting for malignant biliary obstruction: really time to say goodbye?
    Gut. 2023 Oct 5:gutjnl-2023-331070. doi: 10.1136/gutjnl-2023-331070.
    PubMed    


  48. ZECHER BF, Ellinghaus D, Schloer S, Niehrs A, et al
    HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.
    Gut. 2023 Oct 3:gutjnl-2023-329524. doi: 10.1136/gutjnl-2023-329524.
    PubMed     Abstract available


    September 2023
  49. RUSHBROOK SM, Kendall TJ, Zen Y, Albazaz R, et al
    British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma.
    Gut. 2023 Sep 28:gutjnl-2023-330029. doi: 10.1136/gutjnl-2023-330029.
    PubMed     Abstract available


  50. O'ROURKE CJ, Salati M, Rae C, Carpino G, et al
    Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy.
    Gut. 2023 Sep 27:gutjnl-2023-330748. doi: 10.1136/gutjnl-2023-330748.
    PubMed     Abstract available


    August 2023
  51. JAROSOVA J, Zarivnijova L, Cibulkova I, Mares J, et al
    Endoluminal radiofrequency ablation in patients with malignant biliary obstruction: a randomised trial.
    Gut. 2023 Aug 31:gutjnl-2023-329700. doi: 10.1136/gutjnl-2023-329700.
    PubMed     Abstract available


    July 2023
  52. HE X, Gao N, Lv F, Wu F, et al
    Temporal trend of mortality in patients with cirrhosis with primary biliary cholangitis and primary sclerosing cholangitis during the COVID-19 pandemic.
    Gut. 2023 Jul 24:gutjnl-2023-330271. doi: 10.1136/gutjnl-2023-330271.
    PubMed    


    April 2023
  53. LEWINSKA M, Karhus ML, Ellegaard AG, Romero-Gomez M, et al
    Serum lipidome unravels a diagnostic potential in bile acid diarrhoea.
    Gut. 2023 Apr 18:gutjnl-2022-329213. doi: 10.1136/gutjnl-2022-329213.
    PubMed     Abstract available


  54. ZORNIAK M, Sirtl S, Beyer G, Mahajan UM, et al
    Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis.
    Gut. 2023 Apr 18:gutjnl-2022-327955. doi: 10.1136/gutjnl-2022-327955.
    PubMed     Abstract available


    February 2023
  55. HALLENSLEBEN ND, Stassen PMC, Schepers NJ, Besselink MG, et al
    Patient selection for urgent endoscopic retrograde cholangio-pancreatography by endoscopic ultrasound in predicted severe acute biliary pancreatitis (APEC-2): a multicentre prospective study.
    Gut. 2023 Feb 27:gutjnl-2022-328258. doi: 10.1136/gutjnl-2022-328258.
    PubMed     Abstract available


  56. BEYER G, Kasprowicz F, Hannemann A, Aghdassi A, et al
    Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: a population-based, cross-sectional cohort study.
    Gut. 2023 Feb 24:gutjnl-2021-326106. doi: 10.1136/gutjnl-2021-326106.
    PubMed     Abstract available


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