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  Biliary Tract Diseases

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Articles published in J Hepatol

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Single Articles


    December 2025
  1. GENOVESI V, Salani F, Rimini M, Rizzato MD, et al
    Molecular profiling and matched targeted treatment in cholangiocarcinoma: results from the Italian dataset (ANITA).
    J Hepatol. 2025 Dec 26:S0168-8278(25)02735-7. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  2. TRAMPERT DC
    Viral infection as a trigger for primary sclerosing cholangitis in genetically susceptible individuals.
    J Hepatol. 2025 Dec 11:S0168-8278(25)02632-7. doi: 10.1016/j.jhep.2025.
    PubMed    


  3. KEITEL V, Kreissl MC, Goetze T, Droge C, et al
    CAR T-cell therapy induces remission in multiorgan IgG4-related disease with hepatobiliary involvement.
    J Hepatol. 2025 Dec 8:S0168-8278(25)02711-4. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    November 2025
  4. YOON J, Lee CK, Kim JW, Kang B, et al
    Open-label, single-arm, phase 2 trial to investigate the efficacy of sitravatinib plus tislelizumab combination as a second-line treatment for advanced biliary tract cancer.
    J Hepatol. 2025 Nov 24:S0168-8278(25)02626-1. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  5. RODRIGUES PM, Banales JM
    RePARylating biliary tumours to improve the efficacy of chemoimmunotherapy.
    J Hepatol. 2025 Nov 7:S0168-8278(25)02611-X. doi: 10.1016/j.jhep.2025.
    PubMed    


  6. FRANCIS H, Glaser S, Ueno Y, Lesage G, et al
    Corrigendum to 'cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway' (J Hepatol 41 [2004] 528-537).
    J Hepatol. 2025 Nov 7:S0168-8278(25)02563-2. doi: 10.1016/j.jhep.2025.
    PubMed    


  7. ASSIS DN, Hov JR
    Phase 2 Clinical Trials in Primary Sclerosing Cholangitis: Making the Most of Every Opportunity?
    J Hepatol. 2025 Nov 4:S0168-8278(25)02605-4. doi: 10.1016/j.jhep.2025.
    PubMed    


    October 2025
  8. MERZ V
    Two lenses, same picture: interpreting nal-IRI in biliary tract cancer.
    J Hepatol. 2025 Oct 17:S0168-8278(25)02560-7. doi: 10.1016/j.jhep.2025.
    PubMed    


  9. WONG YJ, Lam L, Soret PA, Lemoinne S, et al
    Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis.
    J Hepatol. 2025 Oct 3:S0168-8278(25)02519-X. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  10. CUI T, Sun L, Guo X, Cheng C, et al
    Tumor-derived CD109 orchestrates reprogramming of tumor-associated macrophages to dampen immune response.
    J Hepatol. 2025;83:946-958.
    PubMed     Abstract available


    September 2025
  11. GALANAKIS V, Gribben C, Munteanu A, Cagna M, et al
    Transcriptomic and epigenetic mechanisms controlling cholangiocytes transdifferentiation into hepatocytes.
    J Hepatol. 2025 Sep 29:S0168-8278(25)02516-4. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  12. YU M, Xie P, Yu Q, Zhao Y, et al
    PARG inhibition halts cholangiocarcinoma progression via the Hippo pathway and enhances response to chemotherapy and immunotherapy.
    J Hepatol. 2025 Sep 26:S0168-8278(25)02500-0. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  13. HIRSCHFIELD GM, Kowdley KV, Trivedi PJ, Eksteen B, et al
    Phase II INTEGRIS-PSC trial of bexotegrast, an alphavbeta6/alphavbeta1 integrin inhibitor, in primary sclerosing cholangitis.
    J Hepatol. 2025 Sep 26:S0168-8278(25)02498-5. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  14. MARONI L, Marzioni M
    Reply to "Time to standardize preoperative EUS for lymph node staging in resectable extrahepatic cholangiocarcinoma".
    J Hepatol. 2025 Sep 18:S0168-8278(25)02481-X. doi: 10.1016/j.jhep.2025.
    PubMed    


  15. SUN D, Wang D, Jia L, Wang P, et al
    S1P/S1PR4 Promotes the Differentiation of CD8(+) tissue-resident memory T Cells Aggravating Bile Duct Injury in Biliary Atresia.
    J Hepatol. 2025 Sep 5:S0168-8278(25)02472-9. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    August 2025
  16. DIXON ED, Claudel T, Nardo AD, Riva A, et al
    Erratum to 'Inhibition of ATGL alleviates MASH via impaired PPARa signalling that favours hydrophilic bile acid composition in mice' [J Hepatol 82 (2025) 658-675].
    J Hepatol. 2025 Aug 30:S0168-8278(25)02438-9. doi: 10.1016/j.jhep.2025.
    PubMed    


  17. SCHWINGE D, Schramm C
    Tregs going acid - how cholestasis impairs regulatory T cell function.
    J Hepatol. 2025 Aug 29:S0168-8278(25)02441-9. doi: 10.1016/j.jhep.2025.
    PubMed    


  18. CHAN SL, Lamarca A, Hsu C, Moreno V, et al
    New targets and new drugs for hepatobiliary cancers.
    J Hepatol. 2025 Aug 25:S0168-8278(25)02455-9. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  19. DEL ZOMPO F, Crouchet E, Ostyn T, Nehme Z, et al
    Claudin-1 is a mediator and therapeutic target in primary sclerosing cholangitis.
    J Hepatol. 2025 Aug 20:S0168-8278(25)02440-7. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  20. TRAMPERT DC
    From parts to portal: Recapitulating hepatobiliary microarchitecture using multicellular organoids.
    J Hepatol. 2025 Aug 20:S0168-8278(25)02346-3. doi: 10.1016/j.jhep.2025.
    PubMed    


  21. JEONG H, Oh JH, Ahn HS, Ryoo BY, et al
    Proteogenomic profiling predicts outcomes of adjuvant chemotherapy in extrahepatic cholangiocarcinoma.
    J Hepatol. 2025 Aug 11:S0168-8278(25)02402-X. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  22. ZHANG R, Su L, Fu M, Wang Z, et al
    Corrigendum to: 'CD177(+) cells produce neutrophil extracellular traps that promote biliary atresia' (J Hepatol [2022] 77:1299-1310).
    J Hepatol. 2025 Aug 4:S0168-8278(25)02281-0. doi: 10.1016/j.jhep.2025.
    PubMed    


  23. HE J, Zhang M, Shi Y, Ji Z, et al
    Targeting xanthine oxidoreductase reverses resistance to EGFR tyrosine kinase inhibitors in intrahepatic cholangiocarcinoma.
    J Hepatol. 2025 Aug 2:S0168-8278(25)02382-7. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    July 2025
  24. PU X, Liu Y, Lyu Z, Zhou Y, et al
    B cells drive CCR5(+)CD4(+) tissue-resident memory T cell cytotoxicity via IL-15Ralpha-IL-15 signaling in primary biliary cholangitis.
    J Hepatol. 2025 Jul 17:S0168-8278(25)02340-2. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  25. LIU H, Wang J, Yao Y, Xia T, et al
    Restoration of N-glycosylation via leucine-activated leucyl-tRNA synthetase 1 overcomes chemoresistance in intrahepatic cholangiocarcinoma.
    J Hepatol. 2025 Jul 17:S0168-8278(25)02344-X. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  26. DE JONG DM, Lammers WJ, van Driel LMJW
    Time to standardize preoperative EUS for lymph node staging in resectable extrahepatic cholangiocarcinoma.
    J Hepatol. 2025 Jul 9:S0168-8278(25)02332-3. doi: 10.1016/j.jhep.2025.
    PubMed    


  27. VOGEL A, Saborowski A
    Chasing shadows: navigating surrogate endpoints in biliary tract cancer.
    J Hepatol. 2025 Jul 8:S0168-8278(25)02325-6. doi: 10.1016/j.jhep.2025.
    PubMed    


    June 2025
  28. BEUERS U, Banales JM, Karpen S, Keitel V, et al
    History and prospects of bile acid therapies.
    J Hepatol. 2025 Jun 20:S0168-8278(25)02277-9. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  29. KUDIRA R, Yang ZF, Osuji I, Damen MSMA, et al
    Bile acids engage the SIPR-STAT3 signaling axis to modulate regulatory T cell responses in fibrosing cholangiopathies.
    J Hepatol. 2025 Jun 20:S0168-8278(25)02271-8. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  30. RODRIGUEZ N, Katzenstein C, O'Kula S, Kushner T, et al
    Use of maralixibat in severe and recurrent intrahepatic cholestasis of pregnancy with concurrent benign recurrent intrahepatic cholestasis (BRIC).
    J Hepatol. 2025 Jun 18:S0168-8278(25)02249-4. doi: 10.1016/j.jhep.2025.
    PubMed    


  31. TRAMPERT DC
    Bile acid species as hepatic T lymphocyte response modulators - when bile acids interfere with tumor growth.
    J Hepatol. 2025 Jun 5:S0168-8278(25)00249-1. doi: 10.1016/j.jhep.2025.
    PubMed    


  32. CASTET F, Fabregat-Franco C, Bridgewater J, Kim JW, et al
    Association of candidate surrogate endpoints with overall survival in advanced biliary tract cancer.
    J Hepatol. 2025 Jun 3:S0168-8278(25)02251-2. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    May 2025
  33. GHALLAB A, Mandorfer M, Stirnimann G, Geyer J, et al
    Enteronephrohepatic Circulation of Bile Acids and Therapeutic Potential of Systemic Bile Acid Transporter Inhibitors.
    J Hepatol. 2025 May 23:S0168-8278(25)02207-X. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  34. OH DY, He AR, Qin S, Chen LT, et al
    Durvalumab plus chemotherapy in advanced biliary tract cancer: 3-year overall survival update from the phase III TOPAZ-1 study.
    J Hepatol. 2025 May 15:S0168-8278(25)02201-9. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  35. NIU M, Ding WX
    Overcoming drug resistance by harnessing mitochondrial divisome for treating cholangiocarcinoma.
    J Hepatol. 2025 May 9:S0168-8278(25)02197-X. doi: 10.1016/j.jhep.2025.
    PubMed    


  36. LEVY C, Abouda GF, Bilir BM, Bonder A, et al
    Safety and efficacy of elafibranor in primary sclerosing cholangitis: The ELMWOOD phase II randomized-controlled trial.
    J Hepatol. 2025 May 8:S0168-8278(25)00252-1. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  37. OLAIZOLA I, Odriozola-Gimeno M, Olaizola P, Caballero-Camino FJ, et al
    New platinum derivatives selectively cause double-strand DNA breaks and death in naive and cisplatin-resistant cholangiocarcinomas.
    J Hepatol. 2025 May 3:S0168-8278(25)00293-4. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    April 2025

  38. EASL Clinical Practice Guidelines on the management of extrahepatic cholangiocarcinoma.
    J Hepatol. 2025 Apr 30:S0168-8278(25)00162-X. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  39. LV GY, Mu WT, Cao YN, Sun XD, et al
    Cisplatin-induced Disruption of Mitochondrial Divisome Leads to Enhanced Cisplatin Resistance in Cholangiocarcinoma.
    J Hepatol. 2025 Apr 4:S0168-8278(25)00219-3. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    March 2025
  40. YOO C, Ueno M, Klumpen HJ, Kelley RK, et al
    Health-related quality of life in participants with advanced biliary tract cancer from the randomized phase III KEYNOTE-966 study.
    J Hepatol. 2025 Mar 26:S0168-8278(25)00207-7. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  41. YOO C, Saborowski A, Hyung J, Wenzel P, et al
    Liposomal irinotecan for previously treated patients with biliary tract cancer: A pooled analysis of NIFTY and NALIRICC trials.
    J Hepatol. 2025 Mar 25:S0168-8278(25)00169-2. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  42. GHALLAB A, Gonzalez D, Strangberg E, Hofmann U, et al
    Erratum to: 'Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis' [J Hepatol (2024) 80:268-281].
    J Hepatol. 2025 Mar 15:S0168-8278(25)00140-0. doi: 10.1016/j.jhep.2025.
    PubMed    


  43. KOLEV M, Moller B, Berzigotti A, Semmo N, et al
    Upadacitinib for refractory Primary Biliary Cholangitis.
    J Hepatol. 2025 Mar 12:S0168-8278(25)00159-X. doi: 10.1016/j.jhep.2025.
    PubMed    


    February 2025
  44. TRAMPERT DC
    B cell-depleting anti-CD19 monoclonal antibody holds promise for treating IgG4-related cholangitis.
    J Hepatol. 2025 Feb 27:S0168-8278(25)00070-4. doi: 10.1016/j.jhep.2025.
    PubMed    


  45. KNOX JJ, McNamara MG, Bazin IS, Oh DY, et al
    A phase III randomised study of first-line NUC-1031/cisplatin vs. gemcitabine/cisplatin in advanced biliary tract cancer.
    J Hepatol. 2025 Feb 18:S0168-8278(25)00085-6. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  46. HWANG S, Woo S, Kim C, Chon HJ, et al
    Reply to: Correspondence on 'Concordance of ctDNA and tissue genomic profiling in advanced biliary tract cancer'.
    J Hepatol. 2025 Feb 12:S0168-8278(25)00082-0. doi: 10.1016/j.jhep.2025.
    PubMed    


  47. YOO C
    Response to Zhang et al.: Evaluating Clinical Utility of CT DNA Monitoring for Recurrence Prediction in Resected Extrahepatic Cholangiocarcinoma.
    J Hepatol. 2025 Feb 12:S0168-8278(25)00081-9. doi: 10.1016/j.jhep.2025.
    PubMed    


  48. XUE X, Liu R, Cai Y, Gong L, et al
    Hyodeoxycholic acid ameliorates cholestatic liver fibrosis by facilitating m(6)A-regulated expression of a novel anti-fibrotic target ETV4.
    J Hepatol. 2025 Feb 4:S0168-8278(25)00055-8. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    January 2025
  49. NYHOLM I, Hukkinen M, Lohi J, Sjoblom N, et al
    Accumulation of altered serum bile acids predicts liver injury after portoenterostomy in biliary atresia.
    J Hepatol. 2025 Jan 29:S0168-8278(25)00062-5. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


  50. CHUNG T, Oh S, Won J, Park J, et al
    Genomic and transcriptomic signatures of sequential carcinogenesis from papillary neoplasm to biliary tract cancer.
    J Hepatol. 2025 Jan 18:S0168-8278(25)00013-3. doi: 10.1016/j.jhep.2025.
    PubMed     Abstract available


    December 2024
  51. ZHANG Y, Wang K, Song Z
    Evaluating Clinical Utility of CT DNA Monitoring for Recurrence Prediction in Resected Extrahepatic Cholangiocarcinoma.
    J Hepatol. 2024 Dec 9:S0168-8278(24)02742-9. doi: 10.1016/j.jhep.2024.
    PubMed    


    November 2024
  52. WANG K, Chen Y, Li Y
    Evaluating Concordance and Clinical Utility of ctDNA Profiling in Advanced Biliary Tract Cancer.
    J Hepatol. 2024 Nov 15:S0168-8278(24)02715-6. doi: 10.1016/j.jhep.2024.
    PubMed    


  53. LUO P, Lin A, Miao K
    Balancing strengths and limitations of ctDNA in advanced biliary tract cancer genomic profiling.
    J Hepatol. 2024 Nov 15:S0168-8278(24)02716-8. doi: 10.1016/j.jhep.2024.
    PubMed    


  54. LIU Y, Wei Y, Chen X, Huang S, et al
    Genetic study of intrahepatic cholestasis of pregnancy in Chinese women unveils East Asian etiology linked to historic HBV epidemic.
    J Hepatol. 2024 Nov 13:S0168-8278(24)02708-9. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  55. HENGSTLER JG, Vartak N
    Activating hepatobiliary water channels for gallstone prevention in complicated gallstone disease.
    J Hepatol. 2024 Nov 12:S0168-8278(24)02704-1. doi: 10.1016/j.jhep.2024.
    PubMed    


  56. YOO C, Jeong H, Jeong JH, Kim KP, et al
    Circulating tumor DNA status and dynamics predict recurrence in patients with resected extrahepatic cholangiocarcinoma.
    J Hepatol. 2024 Nov 10:S0168-8278(24)02666-7. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


    October 2024
  57. HWANG S, Woo S, Kang B, Kang H, et al
    Concordance of ctDNA and tissue genomic profiling in advanced biliary tract cancer.
    J Hepatol. 2024 Oct 21:S0168-8278(24)02641-2. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  58. TALANIAN M, Almeqdadi M, Chen HH
    From dark bile to bright insight: A liver biopsy with advanced fibrosis and severe cholestasis.
    J Hepatol. 2024;81:e147-e150.
    PubMed    


  59. YOUNOSSI ZM, Kremer AE, Swain MG, Jones D, et al
    Assessment of fatigue and its impact in chronic liver disease.
    J Hepatol. 2024;81:726-742.
    PubMed     Abstract available


    September 2024
  60. DIXON ED, Claudel T, Nardo AD, Riva A, et al
    Inhibition of ATGL alleviates MASH via impaired PPARalpha signalling that favours hydrophilic bile acid composition in mice.
    J Hepatol. 2024 Sep 30:S0168-8278(24)02577-7. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  61. FUCHS CD, Simbrunner B, Baumgartner M, Campell C, et al
    Bile acid metabolism and signaling in liver disease.
    J Hepatol. 2024 Sep 28:S0168-8278(24)02572-8. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  62. HUO X, Yu Z, Zhao F, Chen Y, et al
    Hepatocyte Aquaporin 8-mediated Water Transport Facilitates Bile Dilution and Prevents Gallstone Formation in Mice.
    J Hepatol. 2024 Sep 24:S0168-8278(24)02563-7. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  63. HENRY L, Younossi ZM
    Fatigue and Patient Reported Outcomes (PROs) in Primary Sclerosing Cholangitis.
    J Hepatol. 2024 Sep 17:S0168-8278(24)02547-9. doi: 10.1016/j.jhep.2024.
    PubMed    


    August 2024
  64. RAVANBAKHSH N, Genyk Y, Cheng A, Vats D, et al
    Biliary Cirrhosis associated with WDR19-Related Ciliopathy in Siblings.
    J Hepatol. 2024 Aug 18:S0168-8278(24)02475-9. doi: 10.1016/j.jhep.2024.
    PubMed    


    July 2024
  65. HUANG P, Wei G, Kirkpatrick JD, Lin Y, et al
    Transposon-based oncogene integration in Abcb4(Mdr2)-/- mice recapitulates high susceptibility to cholangiocarcinoma in primary sclerosing cholangitis.
    J Hepatol. 2024 Jul 30:S0168-8278(24)02423-1. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  66. JOHANNES H, Laura B, Bernd L, Anne T, et al
    Fatigue is a symptom of clinical importance in patients with Primary Sclerosing Cholangitis (SOMA.LIV).
    J Hepatol. 2024 Jul 29:S0168-8278(24)02421-8. doi: 10.1016/j.jhep.2024.
    PubMed    


    June 2024
  67. ESSER H, Kilpatrick AM, Man TY, Aird R, et al
    Primary cilia as a targetable node between biliary injury, senescence and regeneration in liver transplantation.
    J Hepatol. 2024 Jun 13:S0168-8278(24)02302-X. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  68. WU XN, Wang MZ, Zhang N, Zhang W, et al
    Sex-determining region Y gene promotes liver fibrosis and accounts for sexual dimorphism in its pathophysiology.
    J Hepatol. 2024;80:928-940.
    PubMed     Abstract available


    May 2024
  69. MONTANO-LOZA AJ, Lytvyak E, Hirschfield G, Hansen BE, et al
    Prognostic Scores for Ursodeoxycholic Acid-Treated Patients Predict Graft Loss and Mortality in Recurrent Primary Biliary Cholangitis after Liver Transplantation.
    J Hepatol. 2024 May 29:S0168-8278(24)00345-3. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available



  70. EASL Clinical Practice Guidelines on genetic cholestatic liver diseases.
    J Hepatol. 2024 May 29:S0168-8278(24)00274-5. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  71. REVIEJO M, Lozano E, Marin JJG
    Impact of alternative splicing on cholangiocarcinoma progression through metabolic rewiring-induced epigenetic events.
    J Hepatol. 2024 May 27:S0168-8278(24)00365-9. doi: 10.1016/j.jhep.2024.
    PubMed    


  72. KRAUSE J, Schramm C
    Multi-omics characterization of healthy and PSC human liver - what we knew and what we have learned.
    J Hepatol. 2024;80:681-683.
    PubMed    


  73. ANDREWS TS, Nakib D, Perciani CT, Ma XZ, et al
    Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liver.
    J Hepatol. 2024;80:730-743.
    PubMed     Abstract available


    April 2024
  74. YANG L, Niu K, Wang J, Shen W, et al
    Nucleolin lactylation contributes to intrahepatic cholangiocarcinoma pathogenesis via RNA splicing regulation of MADD.
    J Hepatol. 2024 Apr 26:S0168-8278(24)00278-2. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


    March 2024
  75. LEMAIGRE FP
    Planar cell polarity is crucial for proper morphogenesis of the bile ducts.
    J Hepatol. 2024 Mar 26:S0168-8278(24)00217-4. doi: 10.1016/j.jhep.2024.
    PubMed    


  76. XU L, Zhang Y, Lin Z, Deng X, et al
    FASN-mediated fatty acid biosynthesis remodels immune environment in Clonorchis sinensis infection-related intrahepatic cholangiocarcinoma.
    J Hepatol. 2024 Mar 18:S0168-8278(24)00199-5. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  77. RAAB M, Christodoulou E, Krishnankutty R, Gradinaru A, et al
    Van Gogh-like 2 is essential for the architectural patterning of the mammalian biliary tree.
    J Hepatol. 2024 Mar 7:S0168-8278(24)00149-1. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  78. LIM YZ, Zhu M, Wang Y, Sharma T, et al
    Pkd1l1-deficiency drives biliary atresia through ciliary dysfunction in biliary epithelial cells.
    J Hepatol. 2024 Mar 7:S0168-8278(24)00151-X. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


  79. TOMLINSON JL, Li B, Yang J, Loeuillard E, et al
    Syngeneic Murine Models with Distinct Immune Microenvironments Represent Subsets of Human Intrahepatic Cholangiocarcinoma.
    J Hepatol. 2024 Mar 6:S0168-8278(24)00127-2. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


    February 2024
  80. YANG Y, Wang J, Wan J, Cheng Q, et al
    PTEN Deficiency Induces an Extrahepatic Cholangitis-Cholangiocarcinoma Continuum via Aurora kinase A in Mice.
    J Hepatol. 2024 Feb 28:S0168-8278(24)00138-7. doi: 10.1016/j.jhep.2024.
    PubMed     Abstract available


    January 2024
  81. FAN X, Yang F, Zhou L, Yang L, et al
    Mycophenolate mofetil for the induction of remission in primary biliary cholangitis with predominant features of autoimmune hepatitis.
    J Hepatol. 2024 Jan 31:S0168-8278(24)00097-7. doi: 10.1016/j.jhep.2024.
    PubMed    


  82. TANG R, Li Y, Chen R, Ma X, et al
    Reply to "ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort".
    J Hepatol. 2024 Jan 30:S0168-8278(24)00058-8. doi: 10.1016/j.jhep.2024.
    PubMed    


  83. NAYAGAM JS, Miquel R, Thompson RJ, Joshi D, et al
    Genetic cholestasis in children and adults.
    J Hepatol. 2024 Jan 30:S0168-8278(23)05305-9. doi: 10.1016/j.jhep.2023.
    PubMed    


  84. TRAMPERT DC, Beuers U
    A beneficial response of fetal wound healing gone bad in the bile duct: The overarching cause of biliary atresia?
    J Hepatol. 2024 Jan 4:S0168-8278(23)05372-2. doi: 10.1016/j.jhep.2023.
    PubMed    


  85. ZHENG C, Wang L, Zou T, Lian S, et al
    Ileitis promotes MASLD progression via bile acid modulation and enhanced TGR5 signaling in ileal CD8+ T cells.
    J Hepatol. 2024 Jan 3:S0168-8278(24)00004-7. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


    November 2023
  86. KRUK B, Liebe R, Weber SN, Milkiewicz P, et al
    ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort.
    J Hepatol. 2023 Nov 28:S0168-8278(23)05290-X. doi: 10.1016/j.jhep.2023.
    PubMed    


  87. FICKERT P
    Detour of bile acids routes as therapeutic roadmap for cholemic nephropathy.
    J Hepatol. 2023 Nov 25:S0168-8278(23)05283-2. doi: 10.1016/j.jhep.2023.
    PubMed    


  88. DIPERI TP, Zhao M, Evans KW, Varadarajan K, et al
    Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinoma.
    J Hepatol. 2023 Nov 14:S0168-8278(23)05274-1. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  89. VAN MUNSTER KN, Bergquist A, Ponsioen CY
    Inflammatory bowel disease and primary sclerosing cholangitis: One disease or two?
    J Hepatol. 2023 Nov 6:S0168-8278(23)05158-9. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  90. GHALLAB A, Gonzalez D, Strangberg E, Hofmann U, et al
    Inhibition of the Renal Apical Sodium Dependent Bile Acid Transporter Prevents Cholemic Nephropathy in Mice with Obstructive Cholestasis.
    J Hepatol. 2023 Nov 6:S0168-8278(23)05235-2. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


    October 2023
  91. DE JONG IEM, Theise ND, Wells RG
    The space of Mall confirmed in humans: a response to "Portal venous branches as an anatomic railroad for a gut-bile duct axis".
    J Hepatol. 2023 Oct 9:S0168-8278(23)05155-3. doi: 10.1016/j.jhep.2023.
    PubMed    


  92. TRUSSONI CE, LaRusso NF
    Macrophages make a difference in cholestatic liver diseases - but how?
    J Hepatol. 2023 Oct 9:S0168-8278(23)05149-8. doi: 10.1016/j.jhep.2023.
    PubMed    


  93. MALAKAR S, Mishra P, Paturu R, Verma R, et al
    Primary sclerosing cholangitis with high immunoglobulin-G4.
    J Hepatol. 2023 Oct 7:S0168-8278(23)05153-X. doi: 10.1016/j.jhep.2023.
    PubMed    


    September 2023

  94. Corrigendum to "EASL-ILCA clinical practice guidelines on the management of intrahepatic cholangiocarcinoma" [J Hepatol (79) (2023) 181-208].
    J Hepatol. 2023 Sep 23:S0168-8278(23)05092-4. doi: 10.1016/j.jhep.2023.
    PubMed    



  95. Corrigendum to "EASL clinical practice guidelines on sclerosing cholangitis" [J Hepatol (77) 761-806].
    J Hepatol. 2023 Sep 19:S0168-8278(23)05091-2. doi: 10.1016/j.jhep.2023.
    PubMed    


  96. ABERG F, Sallinen V, Tuominen S, Adam R, et al
    Cyclosporine vs. tacrolimus after liver transplantation for primary sclerosing cholangitis - a propensity-score matched intention-to-treat analysis.
    J Hepatol. 2023 Sep 16:S0168-8278(23)05100-0. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


    August 2023
  97. CHEN R, Huang B, Lian M, Wei Y, et al
    A+T rich interaction domain protein 3a (Arid3a) impairs Mertk-mediated efferocytosis in cholestasis.
    J Hepatol. 2023 Aug 31:S0168-8278(23)05069-9. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  98. LIMOUSIN W, Laurent-Puig P, Ziol M, Ganne-Carrie N, et al
    Molecular-based targeted therapies in patients with hepatocellular carcinoma and hepato-cholangiocarcinoma refractory to atezolizumab/bevacizumab.
    J Hepatol. 2023 Aug 28:S0168-8278(23)05070-5. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  99. DE JONG IEM, Hunt ML, Chen D, Du Y, et al
    A fetal wound healing program after intrauterine bile duct injury may contribute to biliary atresia.
    J Hepatol. 2023 Aug 21:S0168-8278(23)05060-2. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  100. KERSTEN R, Trampert DC, Herta T, Hubers LM, et al
    IgG4-related cholangitis - a mimicker of fibrosing and malignant cholangiopathies.
    J Hepatol. 2023 Aug 18:S0168-8278(23)05058-4. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  101. GLESSNER JT, Ningappa MB, Ngo KA, Zahid M, et al
    Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes.
    J Hepatol. 2023 Aug 10:S0168-8278(23)05040-7. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  102. ROMA K, Mohammed S, Sieck B, Naik K, et al
    Kratom-induced acute liver injury: A case study and the importance of herbal supplement regulation.
    J Hepatol. 2023;79:581-584.
    PubMed     Abstract available


    July 2023
  103. DE MARTIN E, Laurent-Bellue A, Routier E, Samuel D, et al
    Acute cholestatic hepatitis in a patient with metastatic melanoma.
    J Hepatol. 2023;79:e13-e15.
    PubMed    


  104. D'ARTISTA L, Moschopoulou AA, Barozzi I, Craig AJ, et al
    MYC determines lineage commitment in KRAS-driven primary liver cancer development.
    J Hepatol. 2023;79:141-149.
    PubMed     Abstract available


    June 2023
  105. ROMEO M, Dallio M, Federico A
    Multidrug Resistance Protein 6 (ABCC6/MRP6) loss of function causing Pseudoxanthoma elasticum (PXE) is associated with Low-Phospholipid Associated Cholelithiasis (LPAC) features: is it time to reconsider the MRP6 role in bile secretion and LPAC geneti
    J Hepatol. 2023 Jun 29:S0168-8278(23)04936-X. doi: 10.1016/j.jhep.2023.
    PubMed    


  106. ARINO S, Aguilar-Bravo B, Coll M, Lee WY, et al
    Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease.
    J Hepatol. 2023 Jun 20:S0168-8278(23)00423-3. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  107. ALMAAS R, Atneosen-Asegg M, Ytre-Arne ME, Melheim M, et al
    Aagenaes syndrome/lymphedema cholestasis syndrome 1 is caused by a founder variant in the 5'-untranslated region of UNC45A.
    J Hepatol. 2023 Jun 14:S0168-8278(23)00410-5. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  108. BRAADLAND PR, Bergquist A, Kummen M, Bossen L, et al
    Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation.
    J Hepatol. 2023 Jun 14:S0168-8278(23)00415-4. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  109. LATTANZI B, Covotta F, Cardinale V
    The Potential Role Of Endoscopy Ultrasound In Primary Sclerosing Cholangitis.
    J Hepatol. 2023 Jun 9:S0168-8278(23)00404-X. doi: 10.1016/j.jhep.2023.
    PubMed    


    May 2023
  110. TOMLINSON JL, Valle JW, Ilyas SI
    Immunobiology of Cholangiocarcinoma.
    J Hepatol. 2023 May 16:S0168-8278(23)00338-0. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  111. BOLDUAN F, Geisel D, Pahl S, Wree A, et al
    Painless jaundice with segmental obstructive cholestasis.
    J Hepatol. 2023 May 9:S0168-8278(23)00209-X. doi: 10.1016/j.jhep.2023.
    PubMed    


    April 2023
  112. GRADY J, Clifford C, Treadwell MC, Parikh ND, et al
    The Use of Fenofibrate for Intrahepatic Cholestasis of Pregnancy.
    J Hepatol. 2023 Apr 19:S0168-8278(23)00237-4. doi: 10.1016/j.jhep.2023.
    PubMed    


  113. DANA J, Debray D, Vilgrain V
    Reply to: "The effects of CFTR modulator therapies on liver stiffness and bile flow: a single centre experience".
    J Hepatol. 2023 Apr 10:S0168-8278(23)00222-2. doi: 10.1016/j.jhep.2023.
    PubMed    


  114. FICKERT P, Lin AC, Ritschl H, Hammer N, et al
    Portal venous branches as an anatomic railroad for a gut-bile duct-axis.
    J Hepatol. 2023 Apr 10:S0168-8278(23)00221-0. doi: 10.1016/j.jhep.2023.
    PubMed    


    March 2023

  115. EASL-ILCA Clinical Practice Guidelines on Intrahepatic Cholangiocarcinoma.
    J Hepatol. 2023 Mar 22:S0168-8278(23)00185-X. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  116. RICCIUTO A, Kamath BM, Hirschfield GM, Trivedi PJ, et al
    Primary sclerosing cholangitis and overlap features of autoimmune hepatitis: a coming of age or an age-ist problem?
    J Hepatol. 2023 Mar 2:S0168-8278(23)00162-9. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


  117. LAPITZ A, Azkargorta M, Milkiewicz P, Olaizola P, et al
    Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis and prognostication of cholangiocarcinoma.
    J Hepatol. 2023 Mar 1:S0168-8278(23)00159-9. doi: 10.1016/j.jhep.2023.
    PubMed     Abstract available


    February 2023
  118. DUWE L, Munoz-Garrido P, Lewinska M, Lafuente-Barquero J, et al
    MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells.
    J Hepatol. 2023;78:364-375.
    PubMed     Abstract available


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