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Brief Communication: Biomarkers as endpoints in cardiovascular clinical trials
-Report from the Cardiovascular Sciences Research Consortium.
Am Heart J. 2026 Jun 18:107511. doi: 10.1016/j.ahj.2026.107511.
PubMed
Combined Effect of Cardiovascular Fitness and Hemodynamic Response to Exercise on
Mortality.
Am J Cardiol. 2026 Jun 12:S0002-9149(26)00395.
PubMed
Abstract available
Cardiovascular Disease as a Multisystem Disorder: Integrating Inflammation,
Metabolism, and Organ Crosstalk.
Angiology. 2026 Jun 17:33197261457709. doi: 10.1177/00033197261457709.
PubMed
Abstract available
P2Y12 inhibitor monotherapy vs. DAPT soon after PCI for ACS increased a composite
of death or ischemic events at 30 d but not at 1 y.
Ann Intern Med. 2026;179:JC66.
PubMed
Abstract available
The interplay of genetics and modifiable risk in atherosclerosis.
Atherosclerosis. 2026;417:120727.
PubMed
Abstract available
Coronary macrovascular and microvascular involvement and their association with
distinct circulating microRNA patterns: The ANFIBIO Study.
Atherosclerosis. 2026;417:120778.
PubMed
Abstract available
Long-term prognostic impact of optical coherence tomography detected plaque
rupture in nonculprit coronary segments.
Atherosclerosis. 2026;417:120681.
PubMed
Abstract available
Standard modifiable cardiovascular risk factors and acute coronary syndrome free
survival.
Atherosclerosis. 2026;417:120616.
PubMed
Abstract available
Identification of near-infrared spectroscopy-defined lipid content within or
adjacent to calcified coronary plaques using optical coherence tomography.
Atherosclerosis. 2026;417:120786.
PubMed
Abstract available
Urinary orosomucoid and the risk of cardiovascular events and all-cause mortality
in the general population. The Tromso Study 2007-2021.
Atherosclerosis. 2026;417:120776.
PubMed
Abstract available
Polygenic risk scores reveal shared polygenic risk across five common
cardiovascular diseases.
Atherosclerosis. 2026;417:120763.
PubMed
Abstract available
Inflammation may explain part of atherosclerotic cardiovascular disease risk
conferred by elevated remnant lipoproteins: a cohort and Mendelian randomization
study.
Atherosclerosis. 2026;417:120772.
PubMed
Abstract available
Lipoprotein(a) cascade screening in coronary artery disease.
Atherosclerosis. 2026;417:120759.
PubMed
Abstract available
Platelet Fc?RIIa Expression Refines Clinical Risk Assessment After Myocardial
Infarction.
Catheter Cardiovasc Interv. 2026 Jun 16. doi: 10.1002/ccd.70691.
PubMed
Abstract available
Diagnostic Yield and Safety of Invasive Coronary Function Testing After Radial
Versus Femoral Access.
Circ Cardiovasc Interv. 2026;19:e016450.
PubMed
Abstract available
Clopidogrel Versus Aspirin Monotherapy Beyond 1 Year After PCI: The Final 5-Year
Results of the STOPDAPT-2 ACS and STOPDAPT-2 Total Cohort.
Circ Cardiovasc Interv. 2026 Mar 18:e016280.
PubMed
Abstract available
uPAR/suPAR Signaling and Organ Crosstalk in Cardiovascular-Kidney-Metabolic
Syndrome.
Circ Res. 2026;139:e328563.
PubMed
Abstract available
A Genome-First Study of Familial Hypercholesterolemia Comparing African and
European Ancestry Individuals.
Circulation. 2026 May 29. doi: 10.1161/CIRCULATIONAHA.126.080694.
PubMed
Abstract available
Defining Cardiovascular Endpoints in Oncology Trials: Challenges and
Opportunities: A Scientific Statement From the American Heart Association.
Circulation. 2026 Jun 15. doi: 10.1161/CIR.0000000000001417.
PubMed
Abstract available
Disparities in Cardiovascular Medicine: Evidence Is Not Enough, Policy Change Is
Essential.
Circulation. 2026;153:1877-1878.
PubMed
Sisyphean Task of Cardiovascular Prevention: Real Gains, Unequal Progress.
Circulation. 2026;153:1879-1881.
PubMed
Pharmacoequity and the Promise of GLP-1 Therapies in Cardiovascular Disease.
Circulation. 2026;153:1884-1886.
PubMed
The Cardiovascular Cost of Medicaid Cuts Under H.R. 1.
Circulation. 2026;153:1882-1883.
PubMed
Sirolimus-Eluting Balloon With Provisional Stenting Versus Systematic
Drug-Eluting Stent Implantation to Treat De Novo Coronary Lesions: A Randomized,
Open-Label, Noninferiority Trial.
Circulation. 2026 Jun 15. doi: 10.1161/CIRCULATIONAHA.126.079033.
PubMed
Abstract available
Impact of Cardiovascular Specialty Care Based on the Humanistic Concept on
Medication Adherence, Glycolipid Metabolism Parameters, and Quality of Life in
High-Risk Cardiovascular Patients With Lipid Management.
Clin Cardiol. 2026;49:e70290.
PubMed
Abstract available
Improved Prediction of Cardiovascular Events Using Serial Cardio-Ankle Vascular
Index (CAVI) Measurements: A 10-Year Prospective Cohort Study.
Clin Cardiol. 2026;49:e70382.
PubMed
Abstract available
Moderate Intensity Statins Plus Ezetimibe Combination Therapy Versus High
Intensity Statins Monotherapy After Percutaneous Coronary Intervention: A
Systematic Review and Meta-Analysis.
Clin Cardiol. 2026;49:e70369.
PubMed
Abstract available
Clinical and Angiographic Predictors of No-Reflow and Its Impact on Outcomes in
ST-Elevation Myocardial Infarction: A Retrospective Study.
Clin Cardiol. 2026;49:e70374.
PubMed
Abstract available
Association Between Comprehensive Health Assessment and Cardiac Mortality and
All-Cause Mortality in Patients With Coronary Heart Disease.
Clin Cardiol. 2026;49:e70378.
PubMed
Abstract available
Uric Acid and Uric Acid Index in Predicting Coronary Artery Disease,
Cerebrovascular Events, and Mortality: A Sex-Stratified Cohort Study.
Clin Cardiol. 2026;49:e70376.
PubMed
Abstract available
Impact of Chronic Kidney Disease Severity on Clinical Outcomes After Drug-Eluting
Stent Implantation: A Propensity Score-Matched Analysis.
Clin Cardiol. 2026;49:e70387.
PubMed
Abstract available
Great debate: the new risk factor-weighted clinical likelihood model is useful to
estimate the initial pre-test probability of obstructive coronary artery disease
in individuals with suspected chronic coronary syndromes.
Eur Heart J. 2026;47:2777-2792.
PubMed
Abstract available
Presence and type of bystanders on delay time in acute myocardial infarction: a
transcultural cross-sectional clinical study with 907 patients in Shanghai and
Munich.
Heart. 2026 Jun 18:heartjnl-2025-327595. doi: 10.1136/heartjnl-2025-327595.
PubMed
Abstract available
Prognosis of patients with ST-elevation myocardial infarction presenting to the
emergency department without chest pain: a retrospective nationwide cohort study.
Heart. 2026 Jun 18:heartjnl-2025-327601. doi: 10.1136/heartjnl-2025-327601.
PubMed
Abstract available
Validation of the European Society of Cardiology 0/1-hour algorithm for chest
pain triage in Asian emergency departments: a multinational stepped-wedge
cluster-randomised trial.
Heart. 2026;112:721-727.
PubMed
Abstract available
Brachial Artery Pulse Pressure: Perspectives on Pathophysiology in Women Without
Obstructive Coronary Disease.
Hypertension. 2026;83:e26833.
PubMed
Plaque characteristics and clinical outcomes of non-culprit long lesions in
patients with acute myocardial infarction.
Int J Cardiol. 2026 Jun 17:134627. doi: 10.1016/j.ijcard.2026.134627.
PubMed
Abstract available
Temporal trends in retrograde crossing of epicardial collaterals in chronic total
occlusion percutaneous coronary intervention.
Int J Cardiol. 2026;459:134586.
PubMed
Abstract available
Transforming post-STEMI care: The IMPACS study design and baseline patient
profile.
Int J Cardiol. 2026;459:134573.
PubMed
Abstract available
Ostial vs proximal stenting in LAD stenosis: A comparative study.
Int J Cardiol. 2026;459:134575.
PubMed
Abstract available
Resistance Training, Aerobic Activity, Television Viewing, and Risk of Major
Cardiovascular Events in U.S. Women.
J Am Coll Cardiol. 2026 May 25:S0735-1097(26)06355.
PubMed
Abstract available
Treatment of Cardiometabolic Risk Factors Among U.S. Adults With
Cardiovascular-Kidney-Metabolic Syndrome.
J Am Coll Cardiol. 2026 Jun 17:S0735-1097(26)06350.
PubMed
Abstract available
Hypertension at an Inflection Point: Aggressive Targets Meet Novel Mechanisms for
Cardiovascular Prevention.
J Am Coll Cardiol. 2026 Jun 5:S0735-1097(26)06489.
PubMed
Abstract available
Interruption of Early Cardiovascular Risk Pathways With GLP-1-Based Therapy for
Obesity.
J Am Coll Cardiol. 2026 Jun 9:S0735-1097(26)06566.
PubMed
Excess Cardiovascular Mortality Among Black Americans, 2000-2024: A JACC Progress
Report.
J Am Coll Cardiol. 2026 Jun 19:S0735-1097(26)06569.
PubMed
Time is muscle, context is key: Re-evaluating the urgency of aVR ST elevation.
J Electrocardiol. 2026;97:154357.
PubMed
Abstract available
Can an artificial intelligence electrocardiogram algorithm improve diagnostic
accuracy for acute coronary occlusion in the difficult subset of canceled
catheterization lab activations?
J Electrocardiol. 2026;97:154255.
PubMed
Abstract available
Long-term survival after percutaneous coronary intervention or coronary artery
bypass grafting in patients with diabetes and multivessel disease.
J Thorac Cardiovasc Surg. 2026 Jun 12:S0022-5223(26)01066.
PubMed
Abstract available
Correction to: Puerarin alleviates myocardial ischemia-reperfusion injury by
enhancing FUNDC1-mediated mitophagy.
Mol Cell Biochem. 2026 Jun 19. doi: 10.1007/s11010-026-05596.
PubMed
Intravascular Ultrasound-Guided or Angiography-Guided Complex High-Risk PCI.
N Engl J Med. 2026;394:2200-2211.
PubMed
Abstract available
Retraction: Analysis of disease burden and future trends of ischemic heart
disease in China and globally, 1990-2023.
PLoS One. 2026;21:e0351803.
PubMed
Understanding participants' experiences of a behaviour change intervention within
cardiac rehabilitation: A nested process evaluation within the STRENGTH
randomised controlled trial.
PLoS One. 2026;21:e0351117.
PubMed
Abstract available
The ARGO dataset: Annotated and delineated intracardiac electrograms of
post-ischemic ventricular tachycardia.
PLoS One. 2026;21:e0350993.
PubMed
Abstract available
Arterial calcification as an imaging biomarker of the risk of stroke, dementia,
and cognitive decline.
Prog Cardiovasc Dis. 2026;95:119-128.
PubMed
Abstract available
Incremental prognostic value of coronary CTA after treadmill testing in
noncardiac surgery candidates: Results from a multicenter prospective cohort.
Prog Cardiovasc Dis. 2026;95:66-73.
PubMed
Abstract available
Revascularization of patients with chronic total occlusion and left ventricular
systolic dysfunction.
Prog Cardiovasc Dis. 2026;95:92-106.
PubMed
Abstract available
Thank you for your interest in scientific medicine.