Home The Word Brain	My Amedeo FAQ Privacy About	Flying Publisher
	Oliena Studio Stroke and language recovery: 9000+ videos Español • Italiano • Sardu • English | PDF+

Ischemic Heart Disease

Free Subscription Articles published in Can J Cardiol Retrieve available abstracts of 79 articles: HTML format Text format

Single Articles

August 2019
1. FORTUNI F, Crimi G, Angelini F, Leonardi S, et al
   Early Complete Revascularization in Hemodynamically Stable Patients With ST-Segment Elevation Myocardial Infarction and Multivessel Disease.
   Can J Cardiol. 2019;35:1047-1057.
   PubMed     Text format     Abstract available
   
   
   July 2019
2. MOHAMED MO, Rashid M, Farooq S, Siddiqui N, et al
   Acute Myocardial Infarction in Severe Mental Illness: Prevalence, Clinical Outcomes, and Process of Care in U.S. Hospitalizations.
   Can J Cardiol. 2019;35:821-830.
   PubMed     Text format     Abstract available
   
   
   
3. KAUR G, Schulman-Marcus J
   The Challenge of Myocardial Infarction in Patients With Mental Illness.
   Can J Cardiol. 2019;35:797-798.
   PubMed     Text format    
   
   
   June 2019
4. HONG Y, Graham MM, Rosychuk RJ, Southern D, et al
   The Effects of Acute Atmospheric Pressure Changes on the Occurrence of ST-Elevation Myocardial Infarction: A Case-Crossover Study.
   Can J Cardiol. 2019;35:753-760.
   PubMed     Text format     Abstract available
   
   
   April 2019
5. CAO Y, He S, Tao Z, Chen W, et al
   Macrophage-Specific IkappaB Kinase alpha Contributes to Ventricular Remodelling and Dysfunction After Myocardial Infarction.
   Can J Cardiol. 2019;35:490-500.
   PubMed     Text format     Abstract available
   
   
   
6. ZHUANG Y, Li T, Zhuang Y, Li Z, et al
   Involvement of lncR-30245 in Myocardial Infarction-Induced Cardiac Fibrosis Through Peroxisome Proliferator-Activated Receptor-gamma-Mediated Connective Tissue Growth Factor Signalling Pathway.
   Can J Cardiol. 2019;35:480-489.
   PubMed     Text format     Abstract available
   
   
   February 2019
7. SAUNDERS A, Stevenson RS
   Marijuana Lollipop-Induced Myocardial Infarction.
   Can J Cardiol. 2019;35:229.
   PubMed     Text format     Abstract available
   
   
   
8. WONG GC, Welsford M, Ainsworth C, Abuzeid W, et al
   2019 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Guidelines on the Acute Management of ST-Elevation Myocardial Infarction: Focused Update on Regionalization and Reperfusion.
   Can J Cardiol. 2019;35:107-132.
   PubMed     Text format     Abstract available
   
   
   January 2019
9. TEIXEIRA T, Hafyane T, Jerosch-Herold M, Marcotte F, et al
   Myocardial Partition Coefficient of Gadolinium: A Pilot Study in Patients With Acute Myocarditis, Chronic Myocardial Infarction, and in Healthy Volunteers.
   Can J Cardiol. 2019;35:51-60.
   PubMed     Text format     Abstract available
   
   
   December 2018
10. KIKUCHI S, Okada K, Hibi K, Maejima N, et al
    Myocardial Infarction Caused by Accelerated Plaque Formation Related to Myocardial Bridge in a Young Man.
    Can J Cardiol. 2018;34:1687.
    PubMed     Text format     Abstract available
    
    
    
11. JIANG Z, Zhang R, Sun M, Liu Q, et al
    Effect of Clopidogrel vs Ticagrelor on Platelet Aggregation and Inflammation Markers After Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction.
    Can J Cardiol. 2018;34:1606-1612.
    PubMed     Text format     Abstract available
    
    
    
12. BERTIC M, Chue CD, Virani S, Davis MK, et al
    Coronary Vasospasm Following Heart Transplantation: Rapid Progression to Aggressive Cardiac Allograft Vasculopathy.
    Can J Cardiol. 2018;34:1687.
    PubMed     Text format     Abstract available
    
    
    
13. BRUNHAM LR, Ruel I, Aljenedil S, Riviere JB, et al
    Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Update 2018.
    Can J Cardiol. 2018;34:1553-1563.
    PubMed     Text format     Abstract available
    
    
    November 2018
14. ANDRADE JG, Deyell MW, Wong GC, Macle L, et al
    Antithrombotic Therapy for Atrial Fibrillation and Coronary Disease Demystified.
    Can J Cardiol. 2018;34:1426-1436.
    PubMed     Text format     Abstract available
    
    
    October 2018
15. PATEREK A, Kepska M, Kolodziejczyk J, Leszek P, et al
    Acute Heart Rate-Dependent Hemodynamic Function of the Heart in the Post-Myocardial Infarction Rat Model: Change Over Time.
    Can J Cardiol. 2018;34:1341-1349.
    PubMed     Text format     Abstract available
    
    
    
16. STONE JA, Alter DA
    The Health Economics of Myocardial Infarction: Black Boxes and Black Holes.
    Can J Cardiol. 2018;34:1253-1255.
    PubMed     Text format    
    
    
    August 2018
17. RAPARELLI V, Elharram M, Shimony A, Eisenberg MJ, et al
    Reply to Madias-The Case of Takotsubo and Myocardial Infarction Without Obstructive Coronary Disease.
    Can J Cardiol. 2018;34:1089.
    PubMed     Text format    
    
    
    
18. CHALKIAS A, Pavlopoulos F, Papageorgiou E, Tountas C, et al
    Development and Testing of a Novel Anaesthesia Induction/Ventilation Protocol for Patients With Cardiogenic Shock Complicating Acute Myocardial Infarction.
    Can J Cardiol. 2018;34:1048-1058.
    PubMed     Text format     Abstract available
    
    
    
19. KOUNIS NG, Koniari I, Soufras GD, Chourdakis E, et al
    The Humble Relation of Kounis Syndrome, MINOCA (Myocardial Infarction With Nonobstructive Coronary Arteries) and MACE (Major Adverse Cardiac Events).
    Can J Cardiol. 2018;34:1089.
    PubMed     Text format    
    
    
    July 2018
20. LADDU D, Ozemek C, Lamb B, Hauer T, et al
    Factors Associated With Cardiorespiratory Fitness at Completion of Cardiac Rehabilitation: Identification of Specific Patient Features Requiring Attention.
    Can J Cardiol. 2018;34:925-932.
    PubMed     Text format     Abstract available
    
    
    
21. HORSMAN C, Frederick T
    Poor Compliance With Carrying Nitroglycerin and Aspirin in Patients With Coronary Artery Disease.
    Can J Cardiol. 2018;34:945.
    PubMed     Text format    
    
    
    June 2018
22. ZHU T, Lavi S, Johri AM
    Physicians' Attitudes Towards Anticoagulation for Prevention and Treatment of Left Ventricular Thrombus Following Anterior Myocardial Infarction.
    Can J Cardiol. 2018 Jun 6. pii: S0828-282X(18)30441.
    PubMed     Text format    
    
    
    
23. TRAN DT, Welsh RC, Ohinmaa A, Thanh NX, et al
    Resource Use and Burden of Hospitalization, Outpatient, Physician, and Drug Costs in Short- and Long-term Care After Acute Myocardial Infarction.
    Can J Cardiol. 2018 Jun 5. pii: S0828-282X(18)30403.
    PubMed     Text format     Abstract available
    
    
    
24. ARBEL Y, Ko DT, Yan AT, Cantor WJ, et al
    Long-term Follow-up of the Trial of Routine Angioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI).
    Can J Cardiol. 2018;34:736-743.
    PubMed     Text format     Abstract available
    
    
    
25. COUTURE EL, Huynh T
    Drip-and-Ship vs Watchful Waiting: What Should Be the Optimal Approach After Fibrinolytic Therapy for Myocardial Infarction With ST-Segment Elevation?
    Can J Cardiol. 2018;34:700-702.
    PubMed     Text format    
    
    
    
26. HADDAD K, Tanguay JF, Potter BJ, Matteau A, et al
    Longer Inflation Duration and Predilation-Sizing-Postdilation Improve Bioresorbable Scaffold Outcomes in a Long-term All-Comers Canadian Registry.
    Can J Cardiol. 2018;34:752-758.
    PubMed     Text format     Abstract available
    
    
    
27. BANACK HR, Harper S, Kaufman JS
    Accounting for Selection Bias in Studies of Acute Cardiac Events.
    Can J Cardiol. 2018;34:709-716.
    PubMed     Text format     Abstract available
    
    
    
28. PESTANA G, Ribeiro V, Sousa C, Cruz C, et al
    Percutaneous Closure of a Fistulous Giant Coronary Aneurysm.
    Can J Cardiol. 2018;34:812.
    PubMed     Text format     Abstract available
    
    
    May 2018
29. RUEL I, Brisson D, Aljenedil S, Awan Z, et al
    Simplified Canadian Definition for Familial Hypercholesterolemia.
    Can J Cardiol. 2018 May 19. pii: S0828-282X(18)30383.
    PubMed     Text format     Abstract available
    
    
    
30. GUANDALINI GS, Bangalore S
    The Potential Effects of New Stent Platforms for Coronary Revascularization in Patients With Diabetes.
    Can J Cardiol. 2018;34:653-664.
    PubMed     Text format     Abstract available
    
    
    April 2018
31. MADIAS JE
    Myocardial Infarction With Nonobstructive Coronary Artery Disease in Patients Younger than 55 Years Old: How Many of Them Had Takotsubo Syndrome?
    Can J Cardiol. 2018 Apr 6. pii: S0828-282X(18)30259.
    PubMed     Text format    
    
    
    
32. TAN NS, Dorian P
    Out-of-Hospital Cardiac Arrest in the Presence of Ischemic Heart Disease: What Is the Long-term Arrhythmic Risk After Revascularization?
    Can J Cardiol. 2018 Apr 6. pii: S0828-282X(18)30252.
    PubMed     Text format     Abstract available
    
    
    
33. RAPARELLI V, Elharram M, Shimony A, Eisenberg MJ, et al
    Myocardial Infarction With No Obstructive Coronary Artery Disease: Angiographic and Clinical Insights in Patients With Premature Presentation.
    Can J Cardiol. 2018;34:468-476.
    PubMed     Text format     Abstract available
    
    
    
34. GARUBA HA, Erthal F, Stadnick E, Alzahrani A, et al
    Optimizing Risk Stratification and Noninvasive Diagnosis of Ischemic Heart Disease in Women.
    Can J Cardiol. 2018;34:400-412.
    PubMed     Text format     Abstract available
    
    
    
35. HESSIAN R, Jabagi H, Ngu JMC, Rubens FD, et al
    Coronary Surgery in Women and the Challenges We Face.
    Can J Cardiol. 2018;34:413-421.
    PubMed     Text format     Abstract available
    
    
    
36. PARVAND M, Rayner-Hartley E, Sedlak T
    Recent Developments in Sex-Related Differences in Presentation, Prognosis, and Management of Coronary Artery Disease.
    Can J Cardiol. 2018;34:390-399.
    PubMed     Text format     Abstract available
    
    
    
37. KURMANN RD, Mankad R
    Atherosclerotic Heart Disease in Women With Autoimmune Rheumatologic Inflammatory Conditions.
    Can J Cardiol. 2018;34:381-389.
    PubMed     Text format     Abstract available
    
    
    
38. SRIVARATHARAJAH K, Abramson BL
    Women and Peripheral Arterial Disease: A Review of Sex Differences in Epidemiology, Clinical Manifestations, and Outcomes.
    Can J Cardiol. 2018;34:356-361.
    PubMed     Text format     Abstract available
    
    
    
39. PARRY M, Bjornnes AK, Victor JC, Ayala AP, et al
    Self-Management Interventions for Women With Cardiac Pain: A Systematic Review and Meta-analysis.
    Can J Cardiol. 2018;34:458-467.
    PubMed     Text format     Abstract available
    
    
    
40. GHISI GLM, Chaves GSDS, Bennett A, Lavie CJ, et al
    The Paucity of Data Addressing the Effects of Cardiac Rehabilitation on Mortality and Morbidity in Women.
    Can J Cardiol. 2018;34:502.
    PubMed     Text format    
    
    
    March 2018
41. GEBHARD CE, Gebhard C, Maafi F, Bertrand MJ, et al
    Hockey Games and the Incidence of ST-Elevation Myocardial Infarction.
    Can J Cardiol. 2018 Mar 20. pii: S0828-282X(18)30003.
    PubMed     Text format     Abstract available
    
    
    
42. FAUBERT C, Heckman G, McKelvie R
    Management of Non-ST-Elevation Myocardial Infarction in Elderly Patients: Time to Consider Frailty and Quality of Life.
    Can J Cardiol. 2018;34:241-243.
    PubMed     Text format    
    
    
    
43. LIU Y, Baranchuk A
    Going Beyond Left Anterior Descending Artery Occlusion: Recognizing the Variable Clinical Associations of the de Winter Pattern on Electrocardiography.
    Can J Cardiol. 2018;34:343.
    PubMed     Text format    
    
    
    
44. POTTER BJ, Matteau A, Noiseux N, Mansour S, et al
    High Stakes: CTO-PCI in the Post-CABG Patient.
    Can J Cardiol. 2018;34:238-240.
    PubMed     Text format    
    
    
    
45. ACHKOUTY G, Amabile N, Zannis K, Veugeois A, et al
    Transcatheter Aortic Valve Replacement for Severe Aortic Regurgitation With Acute Refractory Cardiogenic Shock.
    Can J Cardiol. 2018;34:342.
    PubMed     Text format     Abstract available
    
    
    
46. AZZALINI L, Mitomo S, Hachinohe D, Regazzoli D, et al
    Zero-Contrast Percutaneous Coronary Intervention Guided by Dextran-Based Optical Coherence Tomography.
    Can J Cardiol. 2018;34:342.
    PubMed     Text format     Abstract available
    
    
    
47. CHANDRASEKHAR J, Baber U, Sartori S, Aquino M, et al
    Associations Between Complex PCI and Prasugrel or Clopidogrel Use in Patients With Acute Coronary Syndrome Who Undergo PCI: From the PROMETHEUS Study.
    Can J Cardiol. 2018;34:319-329.
    PubMed     Text format     Abstract available
    
    
    
48. MEHTA SR, Bainey KR, Cantor WJ, Lordkipanidze M, et al
    2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy.
    Can J Cardiol. 2018;34:214-233.
    PubMed     Text format     Abstract available
    
    
    
49. DUCEPPE E, Yusuf S, Tandon V, Rodseth R, et al
    Design of a Randomized Placebo-Controlled Trial to Assess Dabigatran and Omeprazole in Patients with Myocardial Injury after Noncardiac Surgery (MANAGE).
    Can J Cardiol. 2018;34:295-302.
    PubMed     Text format     Abstract available
    
    
    
50. ROA-GARRIDO J, Gomez-Menchero AE, El Amrawy AM, Cardenal-Piris R, et al
    Optical Coherence Tomography Image of Coronary Spasm in a Bioresorbable Vascular Scaffold.
    Can J Cardiol. 2018;34:343.
    PubMed     Text format    
    
    
    
51. AZZALINI L, Ojeda S, Karatasakis A, Maeremans J, et al
    Long-Term Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Patients Who Have Undergone Coronary Artery Bypass Grafting vs Those Who Have Not.
    Can J Cardiol. 2018;34:310-318.
    PubMed     Text format     Abstract available
    
    
    February 2018
52. MIRANDA DF, Lobo AS, Walsh B, Sandoval Y, et al
    New Insights Into the Use of the 12-Lead Electrocardiogram for Diagnosing Acute Myocardial Infarction in the Emergency Department.
    Can J Cardiol. 2018;34:132-145.
    PubMed     Text format     Abstract available
    
    
    
53. ANDRUCHOW JE, Kavsak PA, McRae AD
    Contemporary Emergency Department Management of Patients with Chest Pain: A Concise Review and Guide for the High-Sensitivity Troponin Era.
    Can J Cardiol. 2018;34:98-108.
    PubMed     Text format     Abstract available
    
    
    
54. BOYD JC, Cox JL, Hassan A, Lutchmedial S, et al
    Where you Live in Nova Scotia Can Significantly Impact Your Access to Lifesaving Cardiac Care: Access to Invasive Care Influences Survival.
    Can J Cardiol. 2018;34:202-208.
    PubMed     Text format     Abstract available
    
    
    
55. RANDHAWA VK, Grunau BE, Debicki DB, Zhou J, et al
    Cardiac Intensive Care Unit Management of Patients After Cardiac Arrest: Now the Real Work Begins.
    Can J Cardiol. 2018;34:156-167.
    PubMed     Text format     Abstract available
    
    
    
56. PROBST MA, Noseworthy PA, Brito JP, Hess EP, et al
    Shared Decision-Making as the Future of Emergency Cardiology.
    Can J Cardiol. 2018;34:117-124.
    PubMed     Text format     Abstract available
    
    
    
57. KAVSAK PA, Worster A, Oliver R, Clark L, et al
    Variability Between Reagent Lots for High-Sensitivity Cardiac Troponin I May Affect Performance of Early Rule Out Strategies.
    Can J Cardiol. 2018;34:209.
    PubMed     Text format    
    
    
    January 2018
58. BASTIANY A, Matteau A, Mansour S, Daneault B, et al
    LVT Prophylaxis After Anterior ST-Elevation Myocardial Infarction: A Response to Marquis-Gravel et al.
    Can J Cardiol. 2018;34:93.
    PubMed     Text format    
    
    
    
59. MARQUIS-GRAVEL G, Ghersi I, Boivin-Proulx LA, Verreault-Julien L, et al
    The Ongoing Quest for Optimal Thrombus Prevention After ST-Elevation Myocardial Infarction in the Modern Era.
    Can J Cardiol. 2018;34:93.
    PubMed     Text format    
    
    
    
60. ACHKOUTY G, Dillinger JG, Sideris G, Manzo-Silberman S, et al
    Microcatheter-Facilitated Primary Angioplasty in ST-Segment Elevation Myocardial Infarction.
    Can J Cardiol. 2018;34:23-30.
    PubMed     Text format     Abstract available
    
    
    
61. FRIGERI M, Meyer P, Banfi C, Giraud R, et al
    Immune Checkpoint Inhibitor-Associated Myocarditis: A New Challenge for Cardiologists.
    Can J Cardiol. 2018;34:92.
    PubMed     Text format     Abstract available
    
    
    
62. ARBEL Y, Bennell MC, Goodman SG, Wijeysundera HC, et al
    Cost-Effectiveness of Different Durations of Dual-Antiplatelet Use After Percutaneous Coronary Intervention.
    Can J Cardiol. 2018;34:31-37.
    PubMed     Text format     Abstract available
    
    
    December 2017
63. SARASWAT A, Rahman A, Singh K
    An Invasive vs a Conservative Approach in Elderly Patients with Non-ST-Segment Elevation Myocardial Infarction: Systematic Review and Meta-Analysis.
    Can J Cardiol. 2017 Dec 5. pii: S0828-282X(17)31182.
    PubMed     Text format     Abstract available
    
    
    
64. JEYARAMAN MM, Rabbani R, Copstein L, Sulaiman W, et al
    Autologous Bone Marrow Stem Cell Therapy in Patients With ST-Elevation Myocardial Infarction: A Systematic Review and Meta-analysis.
    Can J Cardiol. 2017;33:1611-1623.
    PubMed     Text format     Abstract available
    
    
    
65. ALZAYER H, Bossard M, Ahsan S, Tsang M, et al
    A Case of Spontaneous Coronary Artery Dissection Complicated by Free Wall Rupture.
    Can J Cardiol. 2017;33:1736.
    PubMed     Text format     Abstract available
    
    
    
66. GRAND'MAISON S, Pilote L, Schlosser K, Stewart DJ, et al
    Clinical Features and Outcomes of Acute Coronary Syndrome in Women With Previous Pregnancy Complications.
    Can J Cardiol. 2017;33:1683-1692.
    PubMed     Text format     Abstract available
    
    
    
67. LIU HL, Wei YJ, Ding P, Zhang J, et al
    Antiplatelet Effect of Different Loading Doses of Ticagrelor in Patients With Non-ST-Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: The APELOT Trial.
    Can J Cardiol. 2017;33:1675-1682.
    PubMed     Text format     Abstract available
    
    
    
68. ABOUKHOUDIR F, Barnay P, Miramont V, Pansieri M, et al
    Delayed Formation of a Massive Atrial Hematoma After Coronary Intervention Manifesting With an Isolated Cough: Multimodality Imaging and Outcome.
    Can J Cardiol. 2017;33:1736.
    PubMed     Text format     Abstract available
    
    
    
69. YBARRA LF, Dautov R, Gibrat C, Dandona S, et al
    Midterm Angina-Related Quality of Life Benefits After Percutaneous Coronary Intervention of Chronic Total Occlusions.
    Can J Cardiol. 2017;33:1668-1674.
    PubMed     Text format     Abstract available
    
    
    November 2017
70. ZELT JGE, Liu PP, Erthal F, deKemp RA, et al
    N-Terminal Pro B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin T Levels Are Related to the Extent of Hibernating Myocardium in Patients With Ischemic Heart Failure.
    Can J Cardiol. 2017;33:1478-1488.
    PubMed     Text format     Abstract available
    
    
    October 2017
71. TRAN DT, Welsh RC, Ohinmaa A, Thanh NX, et al
    Quality of Acute Myocardial Infarction Care in Canada: A 10-Year Review of 30-Day In-Hospital Mortality and 30-Day Hospital Readmission.
    Can J Cardiol. 2017;33:1319-1326.
    PubMed     Text format     Abstract available
    
    
    
72. PAQUETTE M, Dufour R, Baass A
    Scavenger Receptor LOX1 Genotype Predicts Coronary Artery Disease in Patients With Familial Hypercholesterolemia.
    Can J Cardiol. 2017;33:1312-1318.
    PubMed     Text format     Abstract available
    
    
    
73. BASTIANY A, Grenier ME, Matteau A, Mansour S, et al
    Prevention of Left Ventricular Thrombus Formation and Systemic Embolism After Anterior Myocardial Infarction: A Systematic Literature Review.
    Can J Cardiol. 2017;33:1229-1236.
    PubMed     Text format     Abstract available
    
    
    
74. AZZALINI L, Candilio L, McCullough PA, Colombo A, et al
    Current Risk of Contrast-Induced Acute Kidney Injury After Coronary Angiography and Intervention: A Reappraisal of the Literature.
    Can J Cardiol. 2017;33:1225-1228.
    PubMed     Text format     Abstract available
    
    
    
75. BEYER C, Plank F, Friedrich G, Wildauer M, et al
    Effects of Hyperthyroidism on Coronary Artery Disease: A Computed Tomography Angiography Study.
    Can J Cardiol. 2017;33:1327-1334.
    PubMed     Text format     Abstract available
    
    
    
76. SISKIN M, Rao S, Rapkiewicz A, Bangalore S, et al
    A Case of Cardiogenic Shock Secondary to Complement-Mediated Myopericarditis From Influenza B Infection.
    Can J Cardiol. 2017;33:1335.
    PubMed     Text format     Abstract available
    
    
    September 2017
77. GOTTSCHALK BH, Fujii S, Jones PM, Chu MWA, et al
    Atypical Chest Pain and a Blood Blister: More Than Meets the Eye.
    Can J Cardiol. 2017;33:1206.
    PubMed     Text format    
    
    
    August 2017
78. MINTZ GS
    The Curious Incident of Spotty Calcium in Unstable Atherosclerotic Plaque.
    Can J Cardiol. 2017;33:956-958.
    PubMed     Text format    
    
    
    July 2017
79. FRANCAVIGLIA B, Capranzano P, Capodanno D, Barbanti M, et al
    Late Self-Apposition With One-Year Persisting Uncoverage of Malapposed Bioresorbable Polymeric Struts.
    Can J Cardiol. 2017;33:951.
    PubMed     Text format    
    
    

Thank you for your interest in scientific medicine.

AMEDEO Ischemic Heart Disease is free of charge. This policy is made possible thanks to a media sponsorship by Boehringer Ingelheim. Design: