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Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Chronic Heart Failure

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17.03.2025

3 Am J Cardiol
1 Cardiovasc Res
1 Circ Heart Fail
2 Circulation
3 Eur Heart J
6 Eur J Heart Fail
5 Int J Cardiol
3 J Am Coll Cardiol
3 J Card Fail
1 J Mol Cell Cardiol
1 PLoS One
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Cardiol

  1. SHEN Q, Clark L, Diaz F, Pierce J, et al
    Multidimensional Risk Factors for Heart Failure in Hispanic Adults: Findings from the All of Us Research Program.
    Am J Cardiol. 2025 Mar 11:S0002-9149(25)00147.
    PubMed         Abstract available

  2. MUHAMMAD AN, Neppala S, Chigurupati HD, Ali A, et al
    Trends in Cardiac Arrest Among Heart Failure Patients Aged 25 and Older in the United States: Insights from the CDC WONDER Database: Cardiac Arrest Mortality Trends in Heart Failure.
    Am J Cardiol. 2025 Mar 9:S0002-9149(25)00137.
    PubMed        

  3. DE SCHUTTER S, Van Damme E, Van Hout G, Pype LL, et al
    Impact of Exercise on Atrial Functional Mitral Regurgitation and its Ddeterminants. An Exercise Echocardiographic Study.
    Am J Cardiol. 2025 Jan 10:S0002-9149(25)00001.
    PubMed         Abstract available


    Cardiovasc Res

  4. DAVIDSON SM, Andreadou I, Antoniades C, Bartunek J, et al
    Opportunities and challenges for the use of human samples in translational cardiovascular research: a scientific statement of the ESC Working Group on Cellular Biology of the Heart, the ESC Working Group on Cardiovascular Surgery, the ESC Council on B
    Cardiovasc Res. 2025 Mar 14:cvaf023. doi: 10.1093.
    PubMed         Abstract available


    Circ Heart Fail

  5. SHAH SJ, Bonderman D, Borlaug BA, Cleland JGF, et al
    Macitentan for Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Pulmonary Vascular Disease: Results of the SERENADE Randomized Clinical Trial and Open-Label Extension Study.
    Circ Heart Fail. 2025;18:e011381.
    PubMed         Abstract available


    Circulation

  6. FILIPP M, Ge ZD, DeBerge M, Lantz C, et al
    Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.
    Circulation. 2025 Mar 12. doi: 10.1161/CIRCULATIONAHA.124.070248.
    PubMed         Abstract available

  7. DAI H, Lu X, Zhou X
    Letter by Dai et al Regarding Article, "Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction".
    Circulation. 2025;151:e686.
    PubMed        


    Eur Heart J

  8. CREA F
    Focus on amyloidosis, peripartum cardiomyopathy, and heart failure prediction by artificial intelligence applied to ECG.
    Eur Heart J. 2025;46:987-990.
    PubMed        

  9. SLIWA K, Jackson A, Viljoen C, Damasceno A, et al
    Pregnancies in women after peri-partum cardiomyopathy: the global European Society of Cardiology EuroObservational Research Programme Peri-Partum Cardiomyopathy Registry.
    Eur Heart J. 2025;46:1031-1040.
    PubMed         Abstract available

  10. GONZALEZ-LOPEZ E, Maurer MS, Garcia-Pavia P
    Transthyretin amyloid cardiomyopathy: a paradigm for advancing precision medicine.
    Eur Heart J. 2025;46:999-1013.
    PubMed         Abstract available


    Eur J Heart Fail

  11. VOLTERRANI M, Halasz G, Adamopoulos S, Agostoni PG, et al
    Quality of life in heart failure. The heart of the matter. A scientific statement of the Heart Failure Association and the European Association of Preventive Cardiology of the European Society of Cardiology.
    Eur J Heart Fail. 2025 Mar 12. doi: 10.1002/ejhf.3440.
    PubMed         Abstract available

  12. VOORRIPS SN, Palm CL, Saucedo-Orozco H, Mahmoud B, et al
    Myocardial ketone body oxidation contributes to empagliflozin-induced improvements in cardiac contractility in murine heart failure.
    Eur J Heart Fail. 2025 Mar 11. doi: 10.1002/ejhf.3633.
    PubMed         Abstract available

  13. INCIARDI RM, Steven D, Savarese G
    The role of kidney disease progression in heart failure prognosis: Bridging the evidence gap for optimal management.
    Eur J Heart Fail. 2025 Mar 11. doi: 10.1002/ejhf.3643.
    PubMed        

  14. GHIGO A, Ameri P, Asnani A, Bertero E, et al
    Update on preclinical models of cancer therapy-related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio-Oncology, and the ESC Working Group on Cellula
    Eur J Heart Fail. 2025 Mar 11. doi: 10.1002/ejhf.3636.
    PubMed         Abstract available

  15. KARAKASIS P, Lefkou E, Pamporis K, Farmakis D, et al
    Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta-analysis.
    Eur J Heart Fail. 2025 Mar 10. doi: 10.1002/ejhf.3637.
    PubMed         Abstract available

  16. SENNI M, Paruchuru P, Shi V, Bohm M, et al
    Safety and tolerability of sacubitril/valsartan in chronic heart failure and reduced ejection fraction: Results from the open-label extension of the PARADIGM-HF study.
    Eur J Heart Fail. 2025 Mar 9. doi: 10.1002/ejhf.3634.
    PubMed        


    Int J Cardiol

  17. KANI R, Miyamoto Y, Saito T, Watanabe A, et al
    Racial and regional differences in efficacy of sodium-glucose cotransporter 2 inhibitors on cardiorenal outcomes: A systematic review and meta-analysis.
    Int J Cardiol. 2025;426:133079.
    PubMed         Abstract available

  18. GAO S, Li D, Qiao B, Gong Y, et al
    Association of elevated levels of soluble transferrin receptor with left ventricular remodeling and mortality in patients with heart failure: Evidence from observational and genetic investigations.
    Int J Cardiol. 2025 Mar 6:133133. doi: 10.1016/j.ijcard.2025.133133.
    PubMed         Abstract available

  19. STRACQUALURSI M, Nemola G, Santangelo G, Moscardelli S, et al
    Monitoring SGLT2 inhibition effectiveness on pulmonary systolic pressure in heart failure with reduced ejection fraction.
    Int J Cardiol. 2025;428:133136.
    PubMed         Abstract available

  20. PANCALDI E, Adamo M, Pagnesi M, Russo G, et al
    Right heart failure and mortality in patients undergoing transcatheter tricuspid valve interventions.
    Int J Cardiol. 2025 Mar 9:133137. doi: 10.1016/j.ijcard.2025.133137.
    PubMed         Abstract available

  21. PALM CL, de Wit S, Gorter TM, Rienstra M, et al
    Beyond the gut: Systemic levels of short-chain fatty acids are altered in patients with heart failure.
    Int J Cardiol. 2025;428:133124.
    PubMed         Abstract available


    J Am Coll Cardiol

  22. PACKER M
    Do Potassium Binders Block Both the Benefits and the Risks of Mineralocorticoid Receptor Antagonists in Heart Failure?: The Four Anti-Aldosterone Myths.
    J Am Coll Cardiol. 2025;85:985-987.
    PubMed        

  23. TANG WZ, Cai QY, Pan YR, Liu TH, et al
    The Impact of Patiromer on Heart Failure Treatment With Angiotensin Inhibitors and MRAs.
    J Am Coll Cardiol. 2025;85:e113.
    PubMed        

  24. PITT B, Budden J, Anker SD, Butler J, et al
    Reply: The Impact of Patiromer on Heart Failure Treatment With Angiotensin Inhibitors and MRAs.
    J Am Coll Cardiol. 2025;85:e115.
    PubMed        


    J Card Fail

  25. PLATZ E, McDowell K, Gupta DK, Claggett B, et al
    Pulmonary congestion on lung ultrasound in ambulatory patients with heart failure and preserved ejection fraction.
    J Card Fail. 2025 Mar 5:S1071-9164(25)00099.
    PubMed         Abstract available

  26. GOLBUS JR, Martyn T
    Weighing the Benefits of Wearable Devices in Heart Failure Trials.
    J Card Fail. 2025 Mar 7:S1071-9164(25)00107.
    PubMed        

  27. VAN ESSEN BJ, Tromp J, Gevaert AB, de Jong TV, et al
    Activation of neutrophil extracellular trap formation in patients with heart failure and a preserved ejection fraction.
    J Card Fail. 2025 Mar 11:S1071-9164(25)00110.
    PubMed         Abstract available


    J Mol Cell Cardiol

  28. CHEN Z, Zhong M, Lin Y, Zhang W, et al
    METTL7B-induced histone lactylation prevents heart failure by ameliorating cardiac remodelling.
    J Mol Cell Cardiol. 2025 Mar 9:S0022-2828(25)00046.
    PubMed         Abstract available


    PLoS One

  29. SADAT-EBRAHIMI SR, Rezabakhsh A, Aslanabadi N, Asadi M, et al
    Correction: Novel diagnostic potential of miR-1 in patients with acute heart failure.
    PLoS One. 2025;20:e0320341.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  30. ZAGLIA T, Campo A, Moro N, Di Mauro V, et al
    Enhancement of mitochondrial calcium uptake is cardioprotective against maladaptive hypertrophy by retrograde signaling uptuning Akt.
    Proc Natl Acad Sci U S A. 2025;122:e2402639122.
    PubMed         Abstract available


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