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Neoplasms of the CNS

Free Subscription Articles published in Acta Neuropathol Retrieve available abstracts of 65 articles: HTML format

Single Articles

September 2025
1. ARTZI SB, Klausen MN, Harwood DSL, Michaelsen SR, et al
   Spatial transcriptomic analysis reveals lack of response to PD-1 blockade in recurrent glioblastoma.
   Acta Neuropathol. 2025;150:29.
   PubMed     Abstract available
   
   
   
2. NANDAKUMAR S, Mehine M, Kemel Y, Bandlamudi C, et al
   Prospective characterization of germline variants in patients with gliomas and glioneuronal tumors.
   Acta Neuropathol. 2025;150:27.
   PubMed     Abstract available
   
   
   
3. COSTA FD, Alves de Castro JV, Gomes YM, Kulikowski LD, et al
   Pineal region high-grade neuroepithelial tumors with NTRK fusions map to the novel methylation class "diffuse high-grade glioma, IDH-wild type, subtype E".
   Acta Neuropathol. 2025;150:26.
   PubMed    
   
   
   August 2025
4. WEBER KJ, Dettki M, Munzberg M, Zeiner PS, et al
   DNA methylation analysis reveals an epigenetic signature distinctive of high-grade oligodendroglioma.
   Acta Neuropathol. 2025;150:21.
   PubMed     Abstract available
   
   
   
5. MIKKELSEN MK, Li X, Yu K, High AA, et al
   Diffuse leptomeningeal glioneuronal tumor (DLGNT): a comprehensive clinical and molecular analysis.
   Acta Neuropathol. 2025;150:18.
   PubMed     Abstract available
   
   
   
6. KECK MK, Al-Hussaini M, Amayiri N, Yiadom AAB, et al
   PLAG1 fusions define a third subtype of CNS embryonal tumor with PLAG family gene alteration.
   Acta Neuropathol. 2025;150:12.
   PubMed     Abstract available
   
   
   June 2025
7. COTTER JA, Markowitz AL, Castaneda E, Yen CY, et al
   CNS methylation classifiers may misclassify normal developing cerebellar cortex as medulloblastoma.
   Acta Neuropathol. 2025;149:66.
   PubMed    
   
   
   
8. KRECH M, Muench A, Teichmann D, Kuzman P, et al
   Outcome-associated factors in a molecularly defined cohort of central neurocytoma.
   Acta Neuropathol. 2025;149:61.
   PubMed     Abstract available
   
   
   April 2025
9. DWARSHUIS G, Kroon LL, Brandsma D, Noske DP, et al
   Liquid biopsies for the monitoring of gliomas and brain metastases in adults.
   Acta Neuropathol. 2025;149:37.
   PubMed     Abstract available
   
   
   
10. SINGH O, Dampier C, Abdullaev Z, Dazelle K, et al
    Diffuse astrocytoma, AYA-type, frequently MAPK-altered: report of 45 patients.
    Acta Neuropathol. 2025;149:32.
    PubMed     Abstract available
    
    
    March 2025
11. PURKAIT S, Praeger S, Felsberg J, Pauck D, et al
    Strong nuclear expression of HOXB13 is a reliable surrogate marker for DNA methylome profiling to distinguish myxopapillary ependymoma from spinal ependymoma.
    Acta Neuropathol. 2025;149:29.
    PubMed     Abstract available
    
    
    February 2025
12. HINZ F, Friedel D, Korshunov A, Ippen FM, et al
    IDH-mutant astrocytomas with primitive neuronal component have a distinct methylation profile and a higher risk of leptomeningeal spread.
    Acta Neuropathol. 2025;149:12.
    PubMed     Abstract available
    
    
    
13. FRIKER LL, Perwein T, Waha A, Dorner E, et al
    MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma.
    Acta Neuropathol. 2025;149:11.
    PubMed     Abstract available
    
    
    January 2025
14. PAGANI F, Orzan F, Lago S, De Bacco F, et al
    Concurrent RB1 and P53 pathway disruption predisposes to the development of a primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3 transcription.
    Acta Neuropathol. 2025;149:8.
    PubMed     Abstract available
    
    
    
15. MADLENER S, Stepien N, Senfter D, Mayr L, et al
    Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method.
    Acta Neuropathol. 2025;149:5.
    PubMed     Abstract available
    
    
    November 2024
16. MIKOLAJEWICZ N, Tatari N, Wei J, Savage N, et al
    Functional profiling of murine glioma models highlights targetable immune evasion phenotypes.
    Acta Neuropathol. 2024;148:74.
    PubMed     Abstract available
    
    
    
17. JOTANOVIC J, Boldt HB, Burton M, Andersen MS, et al
    Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors.
    Acta Neuropathol. 2024;148:68.
    PubMed     Abstract available
    
    
    October 2024
18. CHUNG HJ, Rajan S, Wu Z, Ferrone CK, et al
    MYB/MYBL1-altered gliomas frequently harbor truncations and non-productive fusions in the MYB and MYBL1 genes.
    Acta Neuropathol. 2024;148:54.
    PubMed     Abstract available
    
    
    
19. GHISAI SA, van Hijfte L, Vallentgoed WR, Tesileanu CMS, et al
    Epigenetic landscape reorganisation and reactivation of embryonic development genes are associated with malignancy in IDH-mutant astrocytoma.
    Acta Neuropathol. 2024;148:50.
    PubMed     Abstract available
    
    
    September 2024
20. NUECHTERLEIN N, Cimino S, Shelbourn A, Ha V, et al
    HOXD12 defines an age-related aggressive subtype of oligodendroglioma.
    Acta Neuropathol. 2024;148:41.
    PubMed     Abstract available
    
    
    
21. STEGAT L, Eckhardt A, Gocke A, Neyazi S, et al
    Integrated analyses reveal two molecularly and clinically distinct subtypes of H3 K27M-mutant diffuse midline gliomas with prognostic significance.
    Acta Neuropathol. 2024;148:40.
    PubMed     Abstract available
    
    
    
22. SOL N, Kooi EJ, Pages-Gallego M, Brandsma D, et al
    Glioblastoma, IDH-wildtype with primarily leptomeningeal localization diagnosed by nanopore sequencing of cell-free DNA from cerebrospinal fluid.
    Acta Neuropathol. 2024;148:35.
    PubMed    
    
    
    
23. HENCH J, Hultschig C, Bratic Hench I, Sadasivan H, et al
    Rapid brain lymphoma diagnostics through nanopore sequencing of cytology-negative cerebrospinal fluid.
    Acta Neuropathol. 2024;148:36.
    PubMed    
    
    
    August 2024
24. TERANISHI Y, Yurchenko A, Tran S, Sievers P, et al
    Correlation between natural history and multi-omics profiling of meningiomas in NF2-related schwannomatosis suggests role of methylation group and immune microenvironment in tumor growth rate.
    Acta Neuropathol. 2024;148:30.
    PubMed    
    
    
    
25. AN S, McCortney K, Walshon J, Leonard K, et al
    Methylation profiling of plasma cell-free DNA in pediatric brain tumor patients.
    Acta Neuropathol. 2024;148:29.
    PubMed    
    
    
    
26. LECLAIR NK, Lucas CG, Mirchia K, McCortney K, et al
    The RNA-binding protein IGF2BP1 regulates stability of mRNA transcribed from FOXM1 target genes in hypermitotic meningiomas.
    Acta Neuropathol. 2024;148:28.
    PubMed    
    
    
    
27. LE QUANG M, Trinquet A, Siegfried A, de Barros A, et al
    FGFR1 wild-type rosette-forming glioneuronal tumours.
    Acta Neuropathol. 2024;148:26.
    PubMed    
    
    
    
28. ZHANG KY, Parker M, Weber-Levine C, Kalluri A, et al
    ASXL1 inactivation and reduced H3K27me3 across central nervous system tumors.
    Acta Neuropathol. 2024;148:19.
    PubMed    
    
    
    
29. MAAS SLN, Hielscher T, Sievers P, Hovestadt V, et al
    Loss over 5% of chromosome 1p is a clinically relevant and applicable cut-off for increased risk of recurrence in meningioma.
    Acta Neuropathol. 2024;148:17.
    PubMed    
    
    
    July 2024
30. PRIESTERBACH-ACKLEY LP, Cordier F, de Witt Hamer P, Snijders TJ, et al
    Diffuse, IDH-wildtype gliomas in adults with minimal histological change and isolated TERT promoter mutation: not simply CNS WHO grade 4.
    Acta Neuropathol. 2024;148:12.
    PubMed    
    
    
    
31. SIEVERS P, Bielle F, Gobel K, Schrimpf D, et al
    Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations.
    Acta Neuropathol. 2024;148:7.
    PubMed    
    
    
    
32. RICHARDSON TE, Walker JM, Hambardzumyan D, Brem S, et al
    Genetic and epigenetic instability as an underlying driver of progression and aggressive behavior in IDH-mutant astrocytoma.
    Acta Neuropathol. 2024;148:5.
    PubMed     Abstract available
    
    
    June 2024
33. OKONECHNIKOV K, Schrimpf D, Koster J, Sievers P, et al
    Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations.
    Acta Neuropathol. 2024;147:95.
    PubMed     Abstract available
    
    
    May 2024
34. LIN AL, Rudneva VA, Richards AL, Zhang Y, et al
    Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory behavior in pituitary neuroendocrine tumors.
    Acta Neuropathol. 2024;147:85.
    PubMed     Abstract available
    
    
    
35. SCHULLER U, Gocke A, Godbole S, Delbridge C, et al
    Anaplastic histology and distinct molecular features in a small series of spinal cord ependymomas.
    Acta Neuropathol. 2024;147:83.
    PubMed    
    
    
    April 2024
36. NASSIRI F, Ajisebutu A, Patil V, Mamatjan Y, et al
    Metabologenomic characterization uncovers a clinically aggressive IDH mutant glioma subtype.
    Acta Neuropathol. 2024;147:68.
    PubMed     Abstract available
    
    
    March 2024
37. REDMER T, Schumann E, Peters K, Weidemeier ME, et al
    Correction to: MET receptor serves as a promising target in melanoma brain metastases.
    Acta Neuropathol. 2024;147:63.
    PubMed    
    
    
    
38. ZAKIMI N, Nguyen MP, Raleigh DR
    Gene transcript fusions are associated with clinical outcomes and molecular groups of meningiomas.
    Acta Neuropathol. 2024;147:57.
    PubMed    
    
    
    February 2024
39. REDMER T, Schumann E, Peters K, Weidemeier ME, et al
    MET receptor serves as a promising target in melanoma brain metastases.
    Acta Neuropathol. 2024;147:44.
    PubMed     Abstract available
    
    
    
40. HARMANCI AS, Boudreau B, Lau S, Hosseingholi Nouri S, et al
    Aggressive human MenG C meningiomas have a molecular counterpart in canines.
    Acta Neuropathol. 2024;147:42.
    PubMed    
    
    
    
41. ZAKIMI N, Mazcko CN, Toedebusch C, Tawa G, et al
    Canine meningiomas are comprised of 3 DNA methylation groups that resemble the molecular characteristics of human meningiomas.
    Acta Neuropathol. 2024;147:43.
    PubMed    
    
    
    
42. RAHMANZADE R, Sahm F
    Reply: pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion.
    Acta Neuropathol. 2024;147:35.
    PubMed    
    
    
    
43. VASILJEVIC A
    Pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion. Scientific commentary on 'Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate diffe
    Acta Neuropathol. 2024;147:34.
    PubMed    
    
    
    January 2024
44. NEYAZI S, Yamazawa E, Hack K, Tanaka S, et al
    Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation.
    Acta Neuropathol. 2024;147:22.
    PubMed     Abstract available
    
    
    
45. DREXLER R, Khatri R, Schuller U, Eckhardt A, et al
    Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma.
    Acta Neuropathol. 2024;147:21.
    PubMed     Abstract available
    
    
    
46. DOTTERMUSCH M, Ryba A, Ricklefs FL, Flitsch J, et al
    Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features.
    Acta Neuropathol. 2024;147:16.
    PubMed     Abstract available
    
    
    December 2023
47. HADAD S, Gupta R, Oberheim Bush NA, Taylor JW, et al
    "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
    Acta Neuropathol. 2023;147:3.
    PubMed     Abstract available
    
    
    
48. AUFFRET L, Ajlil Y, Tauziede-Espariat A, Kergrohen T, et al
    A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation.
    Acta Neuropathol. 2023;147:2.
    PubMed     Abstract available
    
    
    
49. HICKMAN RA, Gedvilaite E, Ptashkin R, Reiner AS, et al
    CDKN2A/B mutations and allele-specific alterations stratify survival outcomes in IDH-mutant astrocytomas.
    Acta Neuropathol. 2023;146:845-847.
    PubMed    
    
    
    
50. RAHMANZADE R, Pfaff E, Banan R, Sievers P, et al
    Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.
    Acta Neuropathol. 2023;146:853-856.
    PubMed    
    
    
    October 2023
51. MAAS SLN, Sievers P, Weber DC, Weller M, et al
    Independent prognostic impact of DNA methylation class and chromosome 1p loss in WHO grade 2 and 3 meningioma undergoing adjuvant high-dose radiotherapy: comprehensive molecular analysis of EORTC 22042-26042.
    Acta Neuropathol. 2023 Oct 19. doi: 10.1007/s00401-023-02642.
    PubMed    
    
    
    
52. ROBERTS HJ, Ji S, Picca A, Sanson M, et al
    Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations.
    Acta Neuropathol. 2023 Oct 18. doi: 10.1007/s00401-023-02640.
    PubMed    
    
    
    
53. PICARD D, Felsberg J, Langini M, Stachura P, et al
    Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma.
    Acta Neuropathol. 2023;146:551-564.
    PubMed     Abstract available
    
    
    September 2023
54. BOETTO J, Plu I, Ducos Y, Blouin A, et al
    Normal meninges harbor oncogenic somatic mutations in meningioma-driver genes.
    Acta Neuropathol. 2023 Sep 26. doi: 10.1007/s00401-023-02635.
    PubMed    
    
    
    
55. TRAN QT, Upadhyaya SA, Billups CA, Onar-Thomas A, et al
    DNA-methylation subgroups carry no prognostic significance in ATRT-SHH patients in clinical trial cohorts.
    Acta Neuropathol. 2023;146:543-545.
    PubMed    
    
    
    
56. JOHANN PD, Altendorf L, Efremova EM, Holsten T, et al
    Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.
    Acta Neuropathol. 2023;146:527-541.
    PubMed     Abstract available
    
    
    August 2023
57. WIRSCHING HG, Felsberg J, Prummer M, Moisoiu V, et al
    Spatial immune profiling of glioblastoma identifies an inflammatory, perivascular phenotype associated with longer survival.
    Acta Neuropathol. 2023 Aug 13. doi: 10.1007/s00401-023-02617.
    PubMed    
    
    
    July 2023
58. WILLIAMS EA, Brastianos PK, Wakimoto H, Zolal A, et al
    A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4.
    Acta Neuropathol. 2023 Jul 31. doi: 10.1007/s00401-023-02609.
    PubMed     Abstract available
    
    
    June 2023
59. MEDICI G, Freudenmann LK, Velz J, Wang SS, et al
    A T-cell antigen atlas for meningioma: novel options for immunotherapy.
    Acta Neuropathol. 2023 Jun 27. doi: 10.1007/s00401-023-02605.
    PubMed     Abstract available
    
    
    
60. MADLENER S, Furtner J, Stepien N, Senfter D, et al
    Clinical applicability of miR517a detection in liquid biopsies of ETMR patients.
    Acta Neuropathol. 2023;145:843-846.
    PubMed    
    
    
    May 2023
61. WANG JZ, Patil V, Liu J, Dogan H, et al
    Correction: Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas.
    Acta Neuropathol. 2023 May 12. doi: 10.1007/s00401-023-02584.
    PubMed    
    
    
    April 2023
62. KORSHUNOV A, Okonechnikov K, Schrimpf D, Tonn S, et al
    Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes.
    Acta Neuropathol. 2023 Apr 24. doi: 10.1007/s00401-023-02575.
    PubMed     Abstract available
    
    
    
63. WANG JZ, Patil V, Liu J, Dogan H, et al
    Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas.
    Acta Neuropathol. 2023 Apr 24. doi: 10.1007/s00401-023-02571.
    PubMed     Abstract available
    
    
    
64. GODDARD J, Castle J, Southworth E, Fletcher A, et al
    Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification.
    Acta Neuropathol. 2023 Apr 4. doi: 10.1007/s00401-023-02566.
    PubMed     Abstract available
    
    
    March 2023
65. BOGUMIL H, Sill M, Schrimpf D, Ismer B, et al
    Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.
    Acta Neuropathol. 2023 Mar 18. doi: 10.1007/s00401-023-02558.
    PubMed     Abstract available
    
    

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