Retrieve available abstracts of 57 articles: HTML format
Single Articles
April 2025
DWARSHUIS G, Kroon LL, Brandsma D, Noske DP, et al Liquid biopsies for the monitoring of gliomas and brain metastases in adults.
Acta Neuropathol. 2025;149:37. PubMedAbstract available
SINGH O, Dampier C, Abdullaev Z, Dazelle K, et al Diffuse astrocytoma, AYA-type, frequently MAPK-altered: report of 45 patients.
Acta Neuropathol. 2025;149:32. PubMedAbstract available
March 2025
PURKAIT S, Praeger S, Felsberg J, Pauck D, et al Strong nuclear expression of HOXB13 is a reliable surrogate marker for DNA
methylome profiling to distinguish myxopapillary ependymoma from spinal
ependymoma.
Acta Neuropathol. 2025;149:29. PubMedAbstract available
February 2025
HINZ F, Friedel D, Korshunov A, Ippen FM, et al IDH-mutant astrocytomas with primitive neuronal component have a distinct
methylation profile and a higher risk of leptomeningeal spread.
Acta Neuropathol. 2025;149:12. PubMedAbstract available
FRIKER LL, Perwein T, Waha A, Dorner E, et al MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening
method for DNA mismatch repair deficiency syndromes in pediatric high-grade
glioma.
Acta Neuropathol. 2025;149:11. PubMedAbstract available
January 2025
PAGANI F, Orzan F, Lago S, De Bacco F, et al Concurrent RB1 and P53 pathway disruption predisposes to the development of a
primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3
transcription.
Acta Neuropathol. 2025;149:8. PubMedAbstract available
MADLENER S, Stepien N, Senfter D, Mayr L, et al Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients
as diagnostic and monitoring biomarker: impact of tumor localization and sampling
method.
Acta Neuropathol. 2025;149:5. PubMedAbstract available
November 2024
MIKOLAJEWICZ N, Tatari N, Wei J, Savage N, et al Functional profiling of murine glioma models highlights targetable immune evasion
phenotypes.
Acta Neuropathol. 2024;148:74. PubMedAbstract available
JOTANOVIC J, Boldt HB, Burton M, Andersen MS, et al Genome-wide methylation profiling differentiates benign from aggressive and
metastatic pituitary neuroendocrine tumors.
Acta Neuropathol. 2024;148:68. PubMedAbstract available
October 2024
CHUNG HJ, Rajan S, Wu Z, Ferrone CK, et al MYB/MYBL1-altered gliomas frequently harbor truncations and non-productive
fusions in the MYB and MYBL1 genes.
Acta Neuropathol. 2024;148:54. PubMedAbstract available
GHISAI SA, van Hijfte L, Vallentgoed WR, Tesileanu CMS, et al Epigenetic landscape reorganisation and reactivation of embryonic development
genes are associated with malignancy in IDH-mutant astrocytoma.
Acta Neuropathol. 2024;148:50. PubMedAbstract available
September 2024
NUECHTERLEIN N, Cimino S, Shelbourn A, Ha V, et al HOXD12 defines an age-related aggressive subtype of oligodendroglioma.
Acta Neuropathol. 2024;148:41. PubMedAbstract available
STEGAT L, Eckhardt A, Gocke A, Neyazi S, et al Integrated analyses reveal two molecularly and clinically distinct subtypes of H3
K27M-mutant diffuse midline gliomas with prognostic significance.
Acta Neuropathol. 2024;148:40. PubMedAbstract available
SOL N, Kooi EJ, Pages-Gallego M, Brandsma D, et al Glioblastoma, IDH-wildtype with primarily leptomeningeal localization diagnosed
by nanopore sequencing of cell-free DNA from cerebrospinal fluid.
Acta Neuropathol. 2024;148:35. PubMed
HENCH J, Hultschig C, Bratic Hench I, Sadasivan H, et al Rapid brain lymphoma diagnostics through nanopore sequencing of cytology-negative
cerebrospinal fluid.
Acta Neuropathol. 2024;148:36. PubMed
August 2024
TERANISHI Y, Yurchenko A, Tran S, Sievers P, et al Correlation between natural history and multi-omics profiling of meningiomas in
NF2-related schwannomatosis suggests role of methylation group and immune
microenvironment in tumor growth rate.
Acta Neuropathol. 2024;148:30. PubMed
AN S, McCortney K, Walshon J, Leonard K, et al Methylation profiling of plasma cell-free DNA in pediatric brain tumor patients.
Acta Neuropathol. 2024;148:29. PubMed
LECLAIR NK, Lucas CG, Mirchia K, McCortney K, et al The RNA-binding protein IGF2BP1 regulates stability of mRNA transcribed from
FOXM1 target genes in hypermitotic meningiomas.
Acta Neuropathol. 2024;148:28. PubMed
LE QUANG M, Trinquet A, Siegfried A, de Barros A, et al FGFR1 wild-type rosette-forming glioneuronal tumours.
Acta Neuropathol. 2024;148:26. PubMed
ZHANG KY, Parker M, Weber-Levine C, Kalluri A, et al ASXL1 inactivation and reduced H3K27me3 across central nervous system tumors.
Acta Neuropathol. 2024;148:19. PubMed
MAAS SLN, Hielscher T, Sievers P, Hovestadt V, et al Loss over 5% of chromosome 1p is a clinically relevant and applicable cut-off for
increased risk of recurrence in meningioma.
Acta Neuropathol. 2024;148:17. PubMed
July 2024
PRIESTERBACH-ACKLEY LP, Cordier F, de Witt Hamer P, Snijders TJ, et al Diffuse, IDH-wildtype gliomas in adults with minimal histological change and
isolated TERT promoter mutation: not simply CNS WHO grade 4.
Acta Neuropathol. 2024;148:12. PubMed
SIEVERS P, Bielle F, Gobel K, Schrimpf D, et al Identification of a putative molecular subtype of adult-type diffuse astrocytoma
with recurrent MAPK pathway alterations.
Acta Neuropathol. 2024;148:7. PubMed
RICHARDSON TE, Walker JM, Hambardzumyan D, Brem S, et al Genetic and epigenetic instability as an underlying driver of progression and
aggressive behavior in IDH-mutant astrocytoma.
Acta Neuropathol. 2024;148:5. PubMedAbstract available
June 2024
OKONECHNIKOV K, Schrimpf D, Koster J, Sievers P, et al Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas
are associated with a predominance in proliferating and progenitor-like cell
subpopulations.
Acta Neuropathol. 2024;147:95. PubMedAbstract available
May 2024
LIN AL, Rudneva VA, Richards AL, Zhang Y, et al Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory
behavior in pituitary neuroendocrine tumors.
Acta Neuropathol. 2024;147:85. PubMedAbstract available
SCHULLER U, Gocke A, Godbole S, Delbridge C, et al Anaplastic histology and distinct molecular features in a small series of spinal
cord ependymomas.
Acta Neuropathol. 2024;147:83. PubMed
April 2024
NASSIRI F, Ajisebutu A, Patil V, Mamatjan Y, et al Metabologenomic characterization uncovers a clinically aggressive IDH mutant
glioma subtype.
Acta Neuropathol. 2024;147:68. PubMedAbstract available
March 2024
REDMER T, Schumann E, Peters K, Weidemeier ME, et al Correction to: MET receptor serves as a promising target in melanoma brain
metastases.
Acta Neuropathol. 2024;147:63. PubMed
ZAKIMI N, Nguyen MP, Raleigh DR Gene transcript fusions are associated with clinical outcomes and molecular
groups of meningiomas.
Acta Neuropathol. 2024;147:57. PubMed
February 2024
REDMER T, Schumann E, Peters K, Weidemeier ME, et al MET receptor serves as a promising target in melanoma brain metastases.
Acta Neuropathol. 2024;147:44. PubMedAbstract available
HARMANCI AS, Boudreau B, Lau S, Hosseingholi Nouri S, et al Aggressive human MenG C meningiomas have a molecular counterpart in canines.
Acta Neuropathol. 2024;147:42. PubMed
ZAKIMI N, Mazcko CN, Toedebusch C, Tawa G, et al Canine meningiomas are comprised of 3 DNA methylation groups that resemble the
molecular characteristics of human meningiomas.
Acta Neuropathol. 2024;147:43. PubMed
RAHMANZADE R, Sahm F Reply: pineal parenchymal tumors of intermediate differentiation: in need of a
stringent definition to avoid confusion.
Acta Neuropathol. 2024;147:35. PubMed
VASILJEVIC A Pineal parenchymal tumors of intermediate differentiation: in need of a stringent
definition to avoid confusion. Scientific commentary on 'Genetical and
epigenetical profiling identifies two subgroups of pineal parenchymal tumors of
intermediate diffe
Acta Neuropathol. 2024;147:34. PubMed
January 2024
NEYAZI S, Yamazawa E, Hack K, Tanaka S, et al Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies
clinically relevant subtypes enriched for tumors with and without NF2 mutation.
Acta Neuropathol. 2024;147:22. PubMedAbstract available
DREXLER R, Khatri R, Schuller U, Eckhardt A, et al Temporal change of DNA methylation subclasses between matched newly diagnosed and
recurrent glioblastoma.
Acta Neuropathol. 2024;147:21. PubMedAbstract available
DOTTERMUSCH M, Ryba A, Ricklefs FL, Flitsch J, et al Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct
clinicopathological and molecular features.
Acta Neuropathol. 2024;147:16. PubMedAbstract available
December 2023
HADAD S, Gupta R, Oberheim Bush NA, Taylor JW, et al "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct
glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
Acta Neuropathol. 2023;147:3. PubMedAbstract available
AUFFRET L, Ajlil Y, Tauziede-Espariat A, Kergrohen T, et al A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a
clinico-radiological and histomolecular characterisation.
Acta Neuropathol. 2023;147:2. PubMedAbstract available
HICKMAN RA, Gedvilaite E, Ptashkin R, Reiner AS, et al CDKN2A/B mutations and allele-specific alterations stratify survival outcomes in
IDH-mutant astrocytomas.
Acta Neuropathol. 2023;146:845-847. PubMed
RAHMANZADE R, Pfaff E, Banan R, Sievers P, et al Genetical and epigenetical profiling identifies two subgroups of pineal
parenchymal tumors of intermediate differentiation (PPTID) with distinct
molecular, histological and clinical characteristics.
Acta Neuropathol. 2023;146:853-856. PubMed
October 2023
MAAS SLN, Sievers P, Weber DC, Weller M, et al Independent prognostic impact of DNA methylation class and chromosome 1p loss in
WHO grade 2 and 3 meningioma undergoing adjuvant high-dose radiotherapy:
comprehensive molecular analysis of EORTC 22042-26042.
Acta Neuropathol. 2023 Oct 19. doi: 10.1007/s00401-023-02642. PubMed
ROBERTS HJ, Ji S, Picca A, Sanson M, et al Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline
glioma long-term survivors reveal a distinct group of tumors with MAPK pathway
alterations.
Acta Neuropathol. 2023 Oct 18. doi: 10.1007/s00401-023-02640. PubMed
PICARD D, Felsberg J, Langini M, Stachura P, et al Integrative multi-omics reveals two biologically distinct groups of pilocytic
astrocytoma.
Acta Neuropathol. 2023;146:551-564. PubMedAbstract available
September 2023
BOETTO J, Plu I, Ducos Y, Blouin A, et al Normal meninges harbor oncogenic somatic mutations in meningioma-driver genes.
Acta Neuropathol. 2023 Sep 26. doi: 10.1007/s00401-023-02635. PubMed
TRAN QT, Upadhyaya SA, Billups CA, Onar-Thomas A, et al DNA-methylation subgroups carry no prognostic significance in ATRT-SHH patients
in clinical trial cohorts.
Acta Neuropathol. 2023;146:543-545. PubMed
JOHANN PD, Altendorf L, Efremova EM, Holsten T, et al Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of
progression on histology, epigenetics, copy number profiling, and
transcriptomics.
Acta Neuropathol. 2023;146:527-541. PubMedAbstract available
August 2023
WIRSCHING HG, Felsberg J, Prummer M, Moisoiu V, et al Spatial immune profiling of glioblastoma identifies an inflammatory, perivascular
phenotype associated with longer survival.
Acta Neuropathol. 2023 Aug 13. doi: 10.1007/s00401-023-02617. PubMed
July 2023
WILLIAMS EA, Brastianos PK, Wakimoto H, Zolal A, et al A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse
high-grade gliomas, CNS WHO grade 4.
Acta Neuropathol. 2023 Jul 31. doi: 10.1007/s00401-023-02609. PubMedAbstract available
June 2023
MEDICI G, Freudenmann LK, Velz J, Wang SS, et al A T-cell antigen atlas for meningioma: novel options for immunotherapy.
Acta Neuropathol. 2023 Jun 27. doi: 10.1007/s00401-023-02605. PubMedAbstract available
MADLENER S, Furtner J, Stepien N, Senfter D, et al Clinical applicability of miR517a detection in liquid biopsies of ETMR patients.
Acta Neuropathol. 2023;145:843-846. PubMed
May 2023
WANG JZ, Patil V, Liu J, Dogan H, et al Correction: Increased mRNA expression of CDKN2A is a transcriptomic marker of
clinically aggressive meningiomas.
Acta Neuropathol. 2023 May 12. doi: 10.1007/s00401-023-02584. PubMed
April 2023
KORSHUNOV A, Okonechnikov K, Schrimpf D, Tonn S, et al Transcriptome analysis stratifies second-generation non-WNT/non-SHH
medulloblastoma subgroups into clinically tractable subtypes.
Acta Neuropathol. 2023 Apr 24. doi: 10.1007/s00401-023-02575. PubMedAbstract available
WANG JZ, Patil V, Liu J, Dogan H, et al Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically
aggressive meningiomas.
Acta Neuropathol. 2023 Apr 24. doi: 10.1007/s00401-023-02571. PubMedAbstract available
GODDARD J, Castle J, Southworth E, Fletcher A, et al Molecular characterisation defines clinically-actionable heterogeneity within
Group 4 medulloblastoma and improves disease risk-stratification.
Acta Neuropathol. 2023 Apr 4. doi: 10.1007/s00401-023-02566. PubMedAbstract available
March 2023
BOGUMIL H, Sill M, Schrimpf D, Ismer B, et al Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features
(GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene
fusions.
Acta Neuropathol. 2023 Mar 18. doi: 10.1007/s00401-023-02558. PubMedAbstract available