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Articles published in Cancer Res

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Single Articles


    February 2020
  1. KIM HS, Chang CY, Yoon HJ, Kim KS, et al
    Glial TIM-3 modulates immune responses in the brain tumor microenvironment.
    Cancer Res. 2020 Feb 24. pii: 0008-5472.CAN-19-2834.
    PubMed     Text format     Abstract available


    January 2020
  2. WIJAYA J, Vo BT, Liu J, Xu B, et al
    An ABC transporter drives medulloblastoma pathogenesis by regulating Sonic Hedgehog signaling.
    Cancer Res. 2020 Jan 16. pii: 0008-5472.CAN-19-2054.
    PubMed     Text format     Abstract available


    December 2019
  3. CHEN Y, Fang R, Yue C, Chang G, et al
    Wnt-Induced Stabilization of KDM4C Is Required for Wnt/beta-Catenin Target Gene Expression and Glioblastoma Tumorigenesis.
    Cancer Res. 2019 Dec 30. pii: 0008-5472.CAN-19-1229.
    PubMed     Text format     Abstract available


  4. WONG RA, Luo X, Lu M, An Z, et al
    Cooperative blockade of PKCalpha and JAK2 drives apoptosis in glioblastoma.
    Cancer Res. 2019 Dec 5. pii: 0008-5472.CAN-18-2808.
    PubMed     Text format     Abstract available


    November 2019
  5. RANDALL EC, Lopez BGC, Peng S, Regan MS, et al
    Localized metabolomic gradients in patient-derived xenograft models of glioblastoma.
    Cancer Res. 2019 Nov 25. pii: 0008-5472.CAN-19-0638.
    PubMed     Text format     Abstract available


  6. ITO H, Watari K, Shibata T, Miyamoto T, et al
    Bi-directional regulation between NDRG1 and GSK3beta controls tumor growth and is targeted by differentiation inducing factor-1 in glioblastoma.
    Cancer Res. 2019 Nov 13. pii: 0008-5472.CAN-19-0438.
    PubMed     Text format     Abstract available


  7. LONG Y, Tao H, Karachi A, Grippin AJ, et al
    Dysregulation of glutamate transport enhances Treg function that promotes VEGF blockade resistance in glioblastoma.
    Cancer Res. 2019 Nov 13. pii: 0008-5472.CAN-19-1577.
    PubMed     Text format     Abstract available


  8. ZHANG Y, Nguyen TTT, Shang E, Mela A, et al
    MET Inhibition Elicits PGC1alpha-Dependent Metabolic Reprogramming in Glioblastoma.
    Cancer Res. 2019 Nov 6. pii: 0008-5472.CAN-19-1389.
    PubMed     Text format     Abstract available


  9. AN Z, Knobbe-Thomsen CB, Wan X, Fan QW, et al
    Correction: EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma.
    Cancer Res. 2019;79:5681.
    PubMed     Text format    


    October 2019
  10. CHEN J, Ananthanarayanan B, Springer KS, Wolf KJ, et al
    Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion.
    Cancer Res. 2019 Oct 22. pii: 0008-5472.CAN-19-1237.
    PubMed     Text format     Abstract available


  11. MCABEE JH, Rath BH, Valdez K, Young DL, et al
    Radiation drives the evolution of orthotopic xenografts initiated from glioblastoma stem-like cells.
    Cancer Res. 2019 Oct 15. pii: 0008-5472.CAN-19-2452.
    PubMed     Text format     Abstract available


    September 2019
  12. LI F, Yi Y, Miao Y, Long W, et al
    N6-methyladenosine Modulates Nonsense-mediated mRNA Decay in Human Glioblastoma.
    Cancer Res. 2019 Sep 17. pii: 0008-5472.CAN-18-2868.
    PubMed     Text format     Abstract available


  13. JUNG J, Zhang Y, Celiku O, Zhang W, et al
    Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma.
    Cancer Res. 2019 Sep 5. pii: 0008-5472.CAN-19-0198.
    PubMed     Text format     Abstract available


    August 2019
  14. SONG X, Wan X, Huang T, Zeng C, et al
    SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes.
    Cancer Res. 2019 Aug 28. pii: 0008-5472.CAN-19-1504.
    PubMed     Text format     Abstract available


  15. OHKA F, Shinjo K, Deguchi S, Matsui Y, et al
    Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-wild-type Diffuse Astrocytic Gliomas.
    Cancer Res. 2019 Aug 20. pii: 0008-5472.CAN-19-1272.
    PubMed     Text format     Abstract available


  16. LI X, Martinez-Ledesma E, Zhang C, Gao F, et al
    Tie2-FGFR1 interaction induces adaptive PI3K inhibitor resistance by upregulating Aurora A/PLK1/CDK1 signaling in glioblastoma.
    Cancer Res. 2019 Aug 15. pii: 0008-5472.CAN-19-0325.
    PubMed     Text format     Abstract available


  17. ZHANG Y, Pusch S, Innes J, Sidlauskas K, et al
    Mutant IDH sensitizes gliomas to endoplasmic reticulum stress and triggers apoptosis by MicroRNA183-mediated inhibition of Semaphorin 3E.
    Cancer Res. 2019 Aug 7. pii: 0008-5472.CAN-19-0054.
    PubMed     Text format     Abstract available


    July 2019
  18. STEPHEN ZR, Chiarelli P, Revia RA, Wang K, et al
    Time-resolved MRI assessment of convection-enhanced delivery by targeted and non-targeted nanoparticles in a human glioblastoma mouse model.
    Cancer Res. 2019 Jul 22. pii: 0008-5472.CAN-18-2998.
    PubMed     Text format     Abstract available


  19. HARA T, Verma IM
    Modeling Gliomas Using Two Recombinases.
    Cancer Res. 2019 Jul 17. pii: 0008-5472.CAN-19-0717.
    PubMed     Text format     Abstract available


  20. SACHDEVA R, Wu M, Smiljanic S, Kaskun O, et al
    ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma.
    Cancer Res. 2019 Jul 10. pii: 0008-5472.CAN-18-1357.
    PubMed     Text format     Abstract available


    June 2019
  21. PELUFFO G, Subedee A, Harper NW, Kingston N, et al
    EN1 is a transcriptional dependency in triple-negative breast cancer associated with brain metastasis.
    Cancer Res. 2019 Jun 25. pii: 0008-5472.CAN-18-3264.
    PubMed     Text format     Abstract available


  22. KONCAR RF, Dey BR, Stanton AJ, Agrawal N, et al
    Identification of novel RAS signaling therapeutic vulnerabilities in Diffuse Intrinsic Pontine Gliomas.
    Cancer Res. 2019 Jun 14. pii: 0008-5472.CAN-18-3521.
    PubMed     Text format     Abstract available


  23. AMIRY-MOGHADDAM M
    AQP4 and the Fate of Gliomas.
    Cancer Res. 2019;79:2810-2811.
    PubMed     Text format     Abstract available


    May 2019
  24. TODOROVA PK, Fletcher-Sananikone E, Mukherjee B, Kollipara R, et al
    Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high grade gliomas.
    Cancer Res. 2019 May 14. pii: 0008-5472.CAN-19-0680.
    PubMed     Text format     Abstract available


  25. AMOOZGAR Z, Jain RK, Duda DG
    Role of Apelin in Glioblastoma Vascularization and Invasion after Anti-VEGF Therapy: What Is the Impact on the Immune System?
    Cancer Res. 2019;79:2104-2106.
    PubMed     Text format     Abstract available


  26. WANG J, Merino DM, Light N, Murphy BL, et al
    Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma.
    Cancer Res. 2019;79:2208-2219.
    PubMed     Text format     Abstract available


    April 2019
  27. HANSEN LJ, Sun R, Yang R, Singh SX, et al
    MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation.
    Cancer Res. 2019 Apr 30. pii: 0008-5472.CAN-18-1010.
    PubMed     Text format     Abstract available


  28. LIU Y, Ji W, Shergalis A, Xu J, et al
    Activation of the unfolded protein response via inhibition of protein disulfide isomerase decreases the capacity for DNA repair to sensitize glioblastoma to radiotherapy.
    Cancer Res. 2019 Apr 17. pii: 0008-5472.CAN-18-2540.
    PubMed     Text format     Abstract available


  29. JIANG Y, Song Y, Wang R, Hu T, et al
    NFAT1-mediated regulation of NDEL1 promotes growth and invasion of glioma stem-like cells.
    Cancer Res. 2019 Apr 2. pii: 0008-5472.CAN-18-3297.
    PubMed     Text format     Abstract available


  30. VOCE DJ, Bernal GM, Wu L, Crawley CD, et al
    Temozolomide treatment induces lncRNA MALAT1 in an NF-small ka, CyrillicB and p53 co-dependent manner in glioblastoma.
    Cancer Res. 2019 Apr 2. pii: 0008-5472.CAN-18-2170.
    PubMed     Text format     Abstract available


    March 2019
  31. XIA S, Ma D, Liu S, Lal B, et al
    Extracellular matrix protein tenascin C increases phagocytosis mediated by CD47 loss of function in glioblastoma.
    Cancer Res. 2019 Mar 21. pii: 0008-5472.CAN-18-3125.
    PubMed     Text format     Abstract available


  32. WOOLMAN M, Kuzan-Fischer CM, Ferry I, Kiyota T, et al
    Picosecond infrared laser desorption mass spectrometry identifies medulloblastoma subgroups on intrasurgical timescales.
    Cancer Res. 2019 Mar 19. pii: 0008-5472.CAN-18-3411.
    PubMed     Text format     Abstract available


  33. SIMONE L, Pisani F, Mola MG, De Bellis M, et al
    AQP4 aggregation state is a determinant for glioma cell fate.
    Cancer Res. 2019 Mar 15. pii: 0008-5472.CAN-18-2015.
    PubMed     Text format     Abstract available


  34. HOFFMAN M, Gillmor A, Kunz DJ, Johnston MJ, et al
    Intratumoral genetic and functional heterogeneity in pediatric glioblastoma.
    Cancer Res. 2019 Mar 15. pii: 0008-5472.CAN-18-3441.
    PubMed     Text format     Abstract available


  35. XIAO W, Zhang R, Sohrabi A, Ehsanipour A, et al
    Correction: Brain-Mimetic 3D Culture Platforms Allow Investigation of Cooperative Effects of Extracellular Matrix Features on Therapeutic Resistance in Glioblastoma.
    Cancer Res. 2019;79:1260.
    PubMed     Text format    


  36. LATHIA JD
    Drak, Drak, Goose: A New Signaling Axis in Glioblastoma.
    Cancer Res. 2019;79:1036-1037.
    PubMed     Text format     Abstract available


  37. TAO R, Murad N, Xu Z, Zhang P, et al
    MYC drives Group 3 medulloblastoma through transformation of Sox2+ astrocyte progenitor cells.
    Cancer Res. 2019 Mar 12. pii: 0008-5472.CAN-18-1787.
    PubMed     Text format     Abstract available


  38. BECKMANN PJ, Larson JD, Larsson AT, Ostergaard JP, et al
    Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
    Cancer Res. 2019;79:905-917.
    PubMed     Text format     Abstract available


    February 2019
  39. VISA A, Sallan MC, Maiques O, Alza L, et al
    T-type Cav3.1 channels mediate progression and chemotherapeutic resistance in glioblastoma.
    Cancer Res. 2019 Feb 12. pii: 0008-5472.CAN-18-1924.
    PubMed     Text format     Abstract available


  40. MASTRELLA G, Hou M, Li M, Stoecklein VM, et al
    Targeting APLN/APLNR improves anti-angiogenic efficiency and blunts pro-invasive side effects of VEGFA/VEGFR2-blockade in glioblastoma.
    Cancer Res. 2019 Feb 4. pii: 0008-5472.CAN-18-0881.
    PubMed     Text format     Abstract available


  41. ATKINS I, Kinnersley B, Ostrom QT, Labreche K, et al
    Transcriptome-wide association study identifies new candidate susceptibility genes for glioma.
    Cancer Res. 2019 Feb 1. pii: 0008-5472.CAN-18-2888.
    PubMed     Text format     Abstract available


    January 2019
  42. PARK HK, Hong JH, Oh YT, Kim SS, et al
    Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells.
    Cancer Res. 2019 Jan 25. pii: 0008-5472.CAN-18-2558.
    PubMed     Text format     Abstract available


  43. DORON H, Pukrop T, Erez N
    A Blazing Landscape: Neuroinflammation Shapes Brain Metastasis.
    Cancer Res. 2019 Jan 24. pii: 0008-5472.CAN-18-1805.
    PubMed     Text format     Abstract available


  44. GOBIN M, Nazarov PV, Warta R, Timmer M, et al
    A DNA repair and cell cycle gene expression signature in primary and recurrent glioblastoma: prognostic value and clinical implications.
    Cancer Res. 2019 Jan 23. pii: 0008-5472.CAN-18-2076.
    PubMed     Text format     Abstract available


  45. SUN T, Patil R, Galstyan A, Klymyshyn D, et al
    Blockade of a laminin-411 - Notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment crosstalk.
    Cancer Res. 2019 Jan 18. pii: 0008-5472.CAN-18-2725.
    PubMed     Text format     Abstract available


    November 2018
  46. MORGAN MA, Canman CE
    Replication Stress: An Achilles' Heel of Glioma Cancer Stem-like Cells.
    Cancer Res. 2018 Nov 29. pii: 0008-5472.CAN-18-2439.
    PubMed     Text format     Abstract available


  47. MA L, Lin K, Chang G, Chen Y, et al
    Aberrant activation of beta-catenin signaling drives glioma tumorigenesis via USP1-mediated stabilization of EZH2.
    Cancer Res. 2018 Nov 13. pii: 0008-5472.CAN-18-1304.
    PubMed     Text format     Abstract available


  48. AN Z, Knobbe-Thomsen CB, Wan X, Fan QW, et al
    EGFR cooperates with EGFRvIII to recruit macrophages in glioblastoma.
    Cancer Res. 2018 Nov 6. pii: 0008-5472.CAN-17-3551.
    PubMed     Text format     Abstract available


  49. MAIR R, Mouliere F, Smith CG, Chandrananda D, et al
    Measurement of plasma cell-free mitochondrial tumor DNA improves detection of glioblastoma in patient-derived orthotopic xenograft models.
    Cancer Res. 2018 Nov 2. pii: 0008-5472.CAN-18-0074.
    PubMed     Text format     Abstract available


    October 2018
  50. AASLAND D, Gotzinger L, Hauck L, Berte N, et al
    Temozolomide induces senescence and repression of DNA repair pathways in glioblastoma cells via activation of ATR-CHK1, p21, and NF-kB.
    Cancer Res. 2018 Oct 25. pii: 0008-5472.CAN-18-1733.
    PubMed     Text format     Abstract available


  51. ALMIRON BONNIN DA, Havrda MC, Israel MA
    Glioma Cell Secretion: A Driver of Tumor Progression and a Potential Therapeutic Target.
    Cancer Res. 2018 Oct 17. pii: 0008-5472.CAN-18-0345.
    PubMed     Text format     Abstract available


  52. LIU T, Xu H, Huang M, Ma W, et al
    Circulating glioma cells exhibit stem cell-like properties.
    Cancer Res. 2018 Oct 15. pii: 0008-5472.CAN-18-0650.
    PubMed     Text format     Abstract available


  53. EINO D, Tsukada Y, Naito H, Kanemura Y, et al
    LPA4-mediated vascular network formation increases the efficacy of anti-PD-1 therapy against brain tumors.
    Cancer Res. 2018 Oct 9. pii: 0008-5472.CAN-18-0498.
    PubMed     Text format     Abstract available


  54. BIRCH JL, Strathdee K, Gilmour L, Vallatos A, et al
    A novel small molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma.
    Cancer Res. 2018 Oct 2. pii: 0008-5472.CAN-18-1697.
    PubMed     Text format     Abstract available


    August 2018
  55. GOUDARZI KM, Espinoza JA, Guo M, Bartek J, et al
    Reduced expression of PROX1 transitions glioblastoma cells into a mesenchymal gene expression subtype.
    Cancer Res. 2018 Aug 22. pii: 0008-5472.CAN-18-0320.
    PubMed     Text format     Abstract available


    July 2018
  56. MAIR R, Wright A, Ros S, Hu DE, et al
    Metabolic imaging detects low levels of glycolytic activity that vary with levels of c-Myc expression in patient-derived xenograft models of glioblastoma.
    Cancer Res. 2018 Jul 27. pii: 0008-5472.CAN-18-0759.
    PubMed     Text format     Abstract available


  57. XING F, Liu Y, Wu SY, Wu K, et al
    Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis.
    Cancer Res. 2018 Jul 19. pii: 0008-5472.CAN-18-1102.
    PubMed     Text format     Abstract available


  58. SINGH M, Venugopal C, Tokar T, McFarlane N, et al
    Therapeutic targeting of the pre-metastatic stage in human brain metastasis.
    Cancer Res. 2018 Jul 9. pii: 0008-5472.CAN-18-1022.
    PubMed     Text format     Abstract available


  59. CARRUTHERS RD, Ahmed SU, Ramachandran S, Strathdee K, et al
    Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells.
    Cancer Res. 2018 Jul 5. pii: 0008-5472.CAN-18-0569.
    PubMed     Text format     Abstract available


  60. WANG R, Zhang S, Chen X, Li N, et al
    CircNT5E acts as a sponge of microRNA-422a to promote glioblastoma tumorigenesis.
    Cancer Res. 2018 Jul 2. pii: 0008-5472.CAN-18-0532.
    PubMed     Text format     Abstract available


    June 2018
  61. QAZI MA, Vora P, Venugopal C, Adams J, et al
    Co-targeting ephrin receptor tyrosine kinases A2 and A3 in cancer stem cells reduces growth of recurrent glioblastoma.
    Cancer Res. 2018 Jun 26. pii: 0008-5472.CAN-18-0267.
    PubMed     Text format     Abstract available


  62. LIANG L, Morrison LC, Tatari N, Stromecki M, et al
    CD271+ cells are diagnostic and prognostic and exhibit elevated MAPK activity in SHH medulloblastoma.
    Cancer Res. 2018 Jun 21. pii: 0008-5472.CAN-18-0027.
    PubMed     Text format     Abstract available


  63. LUOTO S, Hermelo I, Vuorinen EM, Hannus P, et al
    Computational characterization of suppressive immune microenvironments in glioblastoma.
    Cancer Res. 2018 Jun 19. pii: 0008-5472.CAN-17-3714.
    PubMed     Text format     Abstract available


  64. PALLAVICINI G, Sgro F, Garello F, Falcone M, et al
    Inactivation of citron kinase inhibits medulloblastoma progression by inducing apoptosis and cell senescence.
    Cancer Res. 2018 Jun 19. pii: 0008-5472.CAN-17-4060.
    PubMed     Text format     Abstract available


    May 2018
  65. OLMEZ I, Zhang Y, Manigat L, Benamar M, et al
    Combined c-Met/Trk inhibition overcomes resistance to CDK4/6 inhibitors in Glioblastoma.
    Cancer Res. 2018 May 29. pii: 0008-5472.CAN-17-3124.
    PubMed     Text format     Abstract available


  66. MILOUSHEV VZ, Granlund KL, Boltyanskiy R, Lyashchenko SK, et al
    Metabolic Imaging of the Human Brain with Hyperpolarized 13C Pyruvate Demonstrates 13C Lactate Production in Brain Tumor Patients.
    Cancer Res. 2018 May 16. pii: 0008-5472.CAN-18-0221.
    PubMed     Text format     Abstract available


  67. PAL S, Kozono D, Yang X, Fendler W, et al
    Dual HDAC and PI3K inhibition abrogates NFkappaB- and FOXM1-mediated DNA damage response to radiosensitize pediatric high-grade gliomas.
    Cancer Res. 2018 May 14. pii: 0008-5472.CAN-17-3691.
    PubMed     Text format     Abstract available


  68. CHEN Z, Morales JE, Guerrero PA, Sun H, et al
    PTPN12/PTP-PEST Regulates Phosphorylation-Dependent Ubiquitination and Stability of Focal Adhesion Substrates in Invasive Glioblastoma Cells.
    Cancer Res. 2018 May 9. pii: 0008-5472.CAN-18-0085.
    PubMed     Text format     Abstract available


    April 2018
  69. KAID C, Goulart E, Caires-Junior LC, Araujo BHS, et al
    Zika virus selectively kills aggressive human embryonal CNS tumor cells in vitro and in vivo.
    Cancer Res. 2018 Apr 26. pii: 0008-5472.CAN-17-3201.
    PubMed     Text format     Abstract available


  70. LIU J, Sareddy GR, Zhou M, Viswanadhapalli S, et al
    Differential effects of estrogen receptor beta isoforms on glioblastoma progression.
    Cancer Res. 2018 Apr 16. pii: 0008-5472.CAN-17-3470.
    PubMed     Text format     Abstract available


  71. ORLANDO D, Miele E, De Angelis B, Guercio M, et al
    Adoptive immunotherapy using PRAME-specific T cells in medulloblastoma.
    Cancer Res. 2018 Apr 3. pii: 0008-5472.CAN-17-3140.
    PubMed     Text format     Abstract available


    March 2018
  72. REN D, Zhu X, Kong R, Zhao Z, et al
    Targeting Brain-Adaptive Cancer Stem Cells Prohibits Brain Metastatic Colonization of Triple-Negative Breast Cancer.
    Cancer Res. 2018 Mar 22. pii: 0008-5472.CAN-17-2994.
    PubMed     Text format     Abstract available


  73. HALL AW, Battenhouse AM, Shivram H, Morris AR, et al
    Bivalent chromatin domains in glioblastoma reveal a subtype-specific signature of glioma stem cells.
    Cancer Res. 2018 Mar 16. pii: 0008-5472.CAN-17-1724.
    PubMed     Text format     Abstract available


  74. MUKHERJEE J, Johannessen TA, Ohba S, Chow TT, et al
    Mutant IDH1 cooperates with ATRX loss to drive the alternative lengthening of telomere (ALT) phenotype in glioma.
    Cancer Res. 2018 Mar 15. pii: 0008-5472.CAN-17-2269.
    PubMed     Text format     Abstract available


  75. SADAHIRO H, Kang KD, Gibson JT, Minata M, et al
    Activation of the receptor tyrosine kinase AXL regulates the immune microenvironment in glioblastoma.
    Cancer Res. 2018 Mar 12. pii: 0008-5472.CAN-17-2433.
    PubMed     Text format     Abstract available


    February 2018
  76. RIMKUS TK, Carpenter RL, Sirkisoon SR, Zhu D, et al
    Truncated glioma-associated oncogene homolog 1 (tGLI1) mediates mesenchymal glioblastoma via transcriptional activation of CD44.
    Cancer Res. 2018 Feb 20. pii: 0008-5472.CAN-17-2933.
    PubMed     Text format     Abstract available


  77. CHOI JS, Kim CS, Berdis A
    Inhibition of Translesion DNA Synthesis as a Novel Therapeutic Strategy to Treat Brain Cancer.
    Cancer Res. 2018;78:1083-1096.
    PubMed     Text format     Abstract available


  78. DELWAR ZM, Kuo Y, Wen YH, Rennie PS, et al
    Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3.
    Cancer Res. 2018;78:718-730.
    PubMed     Text format     Abstract available


    January 2018
  79. SANG Y, Li Y, Song L, Alvarez AA, et al
    TRIM59 promotes gliomagenesis by inhibiting TC45 dephosphorylation of STAT3.
    Cancer Res. 2018 Jan 31. pii: 0008-5472.CAN-17-2774.
    PubMed     Text format     Abstract available


  80. VISWANATH P, Radoul M, Izquierdo-Garcia JL, Ong WQ, et al
    2-hydroxyglutarate-mediated autophagy of the endoplasmic reticulum leads to an unusual downregulation of phospholipid biosynthesis in mutant IDH1 gliomas.
    Cancer Res. 2018 Jan 22. pii: 0008-5472.CAN-17-2926.
    PubMed     Text format     Abstract available


    December 2017
  81. XIAO W, Zhang R, Sohrabi A, Ehsanipour A, et al
    Brain-Mimetic 3D Culture Platforms Allow Investigation of Cooperative Effects of Extracellular Matrix Features on Therapeutic Resistance in Glioblastoma.
    Cancer Res. 2017 Dec 27. pii: 0008-5472.CAN-17-2429.
    PubMed     Text format     Abstract available


  82. ZHANG Y, Wang T, Wang S, Xiong Y, et al
    Nkx2-2as suppression contributes to the pathogenesis of Sonic Hedgehog medulloblastoma.
    Cancer Res. 2017 Dec 11. pii: 0008-5472.CAN-17-1631.
    PubMed     Text format     Abstract available


  83. WEISS T, Weller M, Guckenberger M, Sentman CL, et al
    NKG2D-based CAR-T cells and radiotherapy exert synergistic efficacy in glioblastoma.
    Cancer Res. 2017 Dec 8. pii: 0008-5472.CAN-17-1788.
    PubMed     Text format     Abstract available


  84. ZAKARIA R, Platt-Higgins A, Rathi N, Radon M, et al
    T cell densities in brain metastases are associated with patient survival times and diffusion tensor MRI changes.
    Cancer Res. 2017 Dec 6. pii: 0008-5472.CAN-17-1720.
    PubMed     Text format     Abstract available


    November 2017
  85. LV D, Jia F, Hou Y, Sang Y, et al
    Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding.
    Cancer Res. 2017;77:6190-6201.
    PubMed     Text format     Abstract available


  86. WAITKUS MS, Pirozzi CJ, Moure CJ, Diplas BH, et al
    Adaptive evolution of the GDH2 allosteric domain promotes gliomagenesis by resolving IDH1R132H induced metabolic liabilities.
    Cancer Res. 2017 Nov 2. pii: canres.1352.2017.
    PubMed     Text format     Abstract available


  87. MIYAUCHI JT, Caponegro MD, Chen D, Choi MK, et al
    Deletion of neuropilin 1 from microglia or bone marrow-derived macrophages slows glioma progression.
    Cancer Res. 2017 Nov 2. pii: canres.1435.2017.
    PubMed     Text format     Abstract available


  88. HOLLON TC, Lewis S, Pandian B, Niknafs YS, et al
    Rapid Intraoperative Diagnosis of Pediatric Brain Tumors Using Stimulated Raman Histology.
    Cancer Res. 2017 Nov 1. pii: canres.1974.2017.
    PubMed     Text format     Abstract available


  89. REAP E, Suryadevara CM, Batich KA, Sanchez-Perez L, et al
    Dendritic cells enhance polyfunctionality of adoptively transferred T cells which target cytomegalovirus in glioblastoma.
    Cancer Res. 2017 Nov 1. pii: canres.0469.2017.
    PubMed     Text format     Abstract available


  90. NORTON I, Essayed W, Zhang F, Pujol S, et al
    SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research.
    Cancer Res. 2017;77:e101-e103.
    PubMed     Text format     Abstract available


    October 2017
  91. LIU Y, Yuelling LW, Wang Y, Du F, et al
    Astrocytes promote medulloblastoma progression through hedgehog secretion.
    Cancer Res. 2017 Oct 6. pii: canres.1463.2017.
    PubMed     Text format     Abstract available


    September 2017
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    Cic loss promotes gliomagenesis via aberrant neural stem cell proliferation and differentiation.
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  93. STEPANOVA DS, Semenova G, Kuo YM, Andrews AJ, et al
    An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis.
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    August 2017
  94. FIGUEROA J, Phillips LM, Shahar T, Hossain A, et al
    Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587.
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  95. LEE E, Pain M, Wang H, Herman JA, et al
    Sensitivity to BUB1B inhibition defines an alternative classification of glioblastoma.
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  96. CHOW KH, Park HJ, George J, Yamamoto K, et al
    S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma.
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  97. CHEN X, Ma H, Wang Z, Zhang S, et al
    EZH2 palmitoylation mediated by ZDHHC5 in p53 mutant glioma drives malignant development and progression.
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    July 2017
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    Transglutaminase 2 inhibition reverses mesenchymal transdifferentiation of glioma stem cells by regulating C/EBPbeta signaling.
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  99. WANG X, Huang Z, Wu Q, Prager BC, et al
    MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells.
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  100. Correction: Wnt5a Drives an Invasive Phenotype in Human Glioblastoma Stem-like Cells.
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    PubMed     Text format    


  101. JERMYN M, Mercier J, Aubertin K, Desroches J, et al
    Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy.
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  102. KURTSDOTTER I, Topcic D, Karlen A, Singla B, et al
    SOX5/6/21 prevent oncogene-driven transformation of brain stem cells.
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    May 2017
  103. YAN H, Romero-Lopez M, Benitez LI, Di K, et al
    3D mathematical modeling of glioblastoma suggests that transdifferentiated vascular endothelial cells mediate resistance to current standard-of-care therapy.
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  104. TECH K, Tikunov AP, Farooq H, Morrissy AS, et al
    Pyruvate kinase inhibits proliferation during postnatal cerebellar neurogenesis and suppresses medulloblastoma formation.
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  105. ZHANG Y, Cruickshanks N, Yuan F, Wang B, et al
    Targetable T-type calcium channels drive glioblastoma.
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  106. GRAUSAM KB, Dooyema SD, Bihannic L, Premathilake H, et al
    ATOH1 promotes leptomeningeal dissemination and metastasis of Sonic Hedgehog subgroup medulloblastomas.
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    April 2017
  107. SARKAR S, Mirzaei R, Zemp FJ, Wu W, et al
    Activation of NOTCH signaling by tenascin-C promotes growth of human brain tumor-initiating cells.
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  108. STEVENS LE, Cheung WKC, Adua SJ, Arnal-Estape A, et al
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  109. ZINNHARDT B, Pigeon H, Theze B, Viel T, et al
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  110. SCHNEPP PM, Lee DD, Guldner IH, O'Tighearnaigh TK, et al
    GAD1 Upregulation Programs Aggressive Features of Cancer Cell Metabolism in the Brain Metastatic Microenvironment.
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    February 2017
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  112. LU Y, Kwintkiewicz J, Liu Y, Tech K, et al
    Chemosensitivity of IDH1 mutant gliomas due to an impairment in PARP1-mediated DNA repair.
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    January 2017
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    Biomarker based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.
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  114. NIKLASSON M, Maddalo G, Sramkova Z, Mutlu E, et al
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    December 2016
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  116. BINDA E, Visioli A, Giani F, Trivieri N, et al
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  117. Correction: IFN-beta Down-Regulates the Expression of DNA Repair Gene MGMT and Sensitizes Resistant Glioma Cells to Temozolomide.
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    PubMed     Text format    


  118. WAHL DR, Dresser J, Wilder-Romans K, Parsels JD, et al
    Glioblastoma therapy can be augmented by targeting IDH1-mediated NADPH biosynthesis.
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    November 2016
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    Mouse Models of Pediatric Supratentorial High-grade Glioma Reveal How Cell-of-Origin Influences Tumor Development and Phenotype.
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  121. ZHU G, Rankin SL, Larson JD, Zhu X, et al
    PTEN signaling in the postnatal perivascular progenitor niche drives medulloblastoma formation.
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    October 2016
  122. NAGEL ZD, Kitange GJ, Gupta SK, Joughin BA, et al
    DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme.
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    September 2016
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    PP2A inhibitor PME-1 drives kinase inhibitor resistance in glioma cells.
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