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  Neoplasms of the CNS

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Articles published in Cancer Res

Retrieve available abstracts of 46 articles:
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Single Articles


    September 2025
  1. KHAN F, Petrosyan E, Liu Y, Bahrami A, et al
    Microglial TBK1 Signaling Promotes Breast Cancer Brain Metastasis.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-25-1791.
    PubMed     Abstract available


  2. CUI Y, Phuong K, Abdelfattah NS, Temple HM, et al
    Quantitative Cell Type Specific Immunopeptidome Analysis of Macrophage and Tumor Co-evolution Reveals Therapeutic MHC-I Peptides in Glioblastoma.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-24-4674.
    PubMed     Abstract available


  3. AHN JY, Dong W, Puri A, Vasquez M, et al
    Spatial Crosstalk Modeling of the Tumor Microenvironment Identifies CCR5-Mediated Glia-to-Glia Signaling as a Key Regulator of Brain Metastatic Progression.
    Cancer Res. 2025 Sep 16. doi: 10.1158/0008-5472.CAN-25-0237.
    PubMed     Abstract available


    August 2025
  4. PAI B, Ramos SI, Cheng WS, Joshi T, et al
    Spatial Multi-omics Defines a Shared Tumor Infiltrative Signature at the Resection Margin in High-Grade Gliomas.
    Cancer Res. 2025 Aug 4. doi: 10.1158/0008-5472.CAN-24-4708.
    PubMed     Abstract available


    July 2025
  5. LIU G, Zhang H, Chen S, Gao J, et al
    Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-25-0419.
    PubMed     Abstract available


  6. RICHMAN CM, Rasnitsyn A, Holgado BL, Vladoiu M, et al
    Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiation Therapy.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-24-3894.
    PubMed     Abstract available


    June 2025
  7. KHAN KA, Qureshi AA, Xu P, Kuo HY, et al
    Immunological Tolerance to Luciferase and Fluorescent Proteins Using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis.
    Cancer Res. 2025;85:2165-2178.
    PubMed     Abstract available


    May 2025
  8. BALAKRISHNAN I, Madhavan K, Pierce A, Michlin J, et al
    Development of an Anti-CD99 Antibody Enables Targeting of Diffuse Midline Glioma.
    Cancer Res. 2025 May 27. doi: 10.1158/0008-5472.CAN-24-5027.
    PubMed     Abstract available


    April 2025
  9. SANG Y, Li Y, Song L, Alvarez AA, et al
    Editor's Note: TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.
    Cancer Res. 2025;85:1342.
    PubMed    


    March 2025
  10. KONG Y, Wang F, Jing R, Zhao Q, et al
    Targeting the SP/KLF Transcriptional Regulatory Network Synergizes with HDAC Inhibition to Impede Progression of H3K27M Diffuse Intrinsic Pontine Glioma.
    Cancer Res. 2025 Mar 7. doi: 10.1158/0008-5472.CAN-24-2227.
    PubMed     Abstract available


    February 2025
  11. NOWICKA Z, Rentzeperis F, Tagal V, Teer JK, et al
    Interactions Between Ploidy and Resource Availability Shape Clonal Evolution in Glioblastoma.
    Cancer Res. 2025 Feb 11. doi: 10.1158/0008-5472.CAN-24-0401.
    PubMed     Abstract available


  12. IPPOLITOV D, Lin YH, Spence J, Glogowska A, et al
    The Brain-Penetrant Pan ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases.
    Cancer Res. 2025 Feb 11. doi: 10.1158/0008-5472.CAN-24-1793.
    PubMed     Abstract available


    January 2025
  13. LIU T, Sun T, Chen X, Wu J, et al
    Targeting ARPC1B Overcomes Immune Checkpoint Inhibitor Resistance in Glioblastoma by Reversing Pro-tumorigenic Macrophage Polarization.
    Cancer Res. 2025 Jan 22. doi: 10.1158/0008-5472.CAN-24-2286.
    PubMed     Abstract available


  14. ORR BA
    Transcription Factor Fingerprint Provides Clues for Brain Tumor Cell of Origin.
    Cancer Res. 2025;85:195-196.
    PubMed     Abstract available


  15. JESSA S, De Cola A, Chandarana B, McNicholas M, et al
    FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System Neuroblastoma.
    Cancer Res. 2025;85:231-250.
    PubMed     Abstract available


  16. NINOMIYA T, Kemmotsu N, Mukohara F, Magari M, et al
    Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy.
    Cancer Res. 2025 Jan 13. doi: 10.1158/0008-5472.CAN-24-2274.
    PubMed     Abstract available


    December 2024
  17. DRUCKER KL, Jenkins RB, Schramek D
    Switching Drivers: Epigenetic Rewiring to Genetic Progression in Glioma.
    Cancer Res. 2024 Dec 30. doi: 10.1158/0008-5472.CAN-24-4907.
    PubMed     Abstract available


  18. WU CY, Chen Y, Lin YJ, Wei KC, et al
    Tumor-Associated Microglia Secrete Extracellular ATP to Support Glioblastoma Progression.
    Cancer Res. 2024;84:4017-4030.
    PubMed     Abstract available


    November 2024
  19. ZHOU Z, Yin X, Sun H, Lu J, et al
    PTBP1 Lactylation Promotes Glioma Stem Cell Maintenance through PFKFB4-Driven Glycolysis.
    Cancer Res. 2024 Nov 21. doi: 10.1158/0008-5472.CAN-24-1412.
    PubMed     Abstract available


  20. IZAR B, Kim M
    Peritumoral Venous Vessels: Autobahn and Portal for T cells to Melanoma Brain Metastasis.
    Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-4054.
    PubMed     Abstract available


  21. CHEN X, Geng Y, Wei G, He D, et al
    Neural Circuitries between the Brain and Peripheral Solid Tumors.
    Cancer Res. 2024;84:3509-3521.
    PubMed     Abstract available


    October 2024
  22. CHEN D, Le SB, Manektalia H, Liu T, et al
    The EP3-ZNF488 Axis Promotes Self-Renewal of Glioma Stem-like Cells to Induce Resistance to Tumor Treating Fields.
    Cancer Res. 2024 Oct 16. doi: 10.1158/0008-5472.CAN-23-3643.
    PubMed     Abstract available


  23. RIMKUS TK, Carpenter RL, Sirkisoon S, Zhu D, et al
    Editor's Note: Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44.
    Cancer Res. 2024;84:3310.
    PubMed    


    September 2024
  24. PANG L, Zhou F, Chen P
    Lipid-laden macrophages recycle myelin to feed glioblastoma.
    Cancer Res. 2024 Sep 18. doi: 10.1158/0008-5472.CAN-24-3362.
    PubMed     Abstract available


    August 2024
  25. LEE C, Yu D, Kim HS, Kim KS, et al
    Galectin-9 Mediates the Functions of Microglia in the Hypoxic Brain Tumor Microenvironment.
    Cancer Res. 2024 Aug 29. doi: 10.1158/0008-5472.CAN-23-3878.
    PubMed     Abstract available


  26. MACLEOD G, Molaei F, Haider S, Almeida MP, et al
    Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities.
    Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-4024.
    PubMed     Abstract available


  27. JIAO M, Pirozzi CJ, Yu C, Bao X, et al
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma.
    Cancer Res. 2024 Aug 1. doi: 10.1158/0008-5472.CAN-24-0134.
    PubMed     Abstract available


    July 2024
  28. NAIR NU, Schaffer AA, Gertz EM, Cheng K, et al
    Chromosome 7 gain compensates for chromosome 10 loss in glioma.
    Cancer Res. 2024 Jul 30. doi: 10.1158/0008-5472.CAN-24-1366.
    PubMed     Abstract available


    April 2024
  29. LOW JCM, Cao J, Hesse F, Wright AJ, et al
    Deuterium metabolic imaging differentiates glioblastoma metabolic subtypes and detects early response to chemoradiotherapy.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2552.
    PubMed     Abstract available


    March 2024
  30. HWANG GH, Pazyra-Murphy MF, Seo HS, Dhe-Paganon S, et al
    A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.
    Cancer Res. 2024;84:872-886.
    PubMed     Abstract available


    February 2024
  31. LI J, Shih LK, Brat DJ
    Integrated Proteogenomics Uncover Mechanisms of Glioblastoma Evolution, Pointing to Novel Therapeutic Targets.
    Cancer Res. 2024 Feb 8. doi: 10.1158/0008-5472.CAN-24-0452.
    PubMed     Abstract available


    January 2024
  32. UNDERHILL HR, Karsy M, Davidson CJ, Hellwig S, et al
    Subclonal Cancer Driver Mutations are Prevalent in the Unresected Peritumoral Edema of Adult Diffuse Gliomas.
    Cancer Res. 2024 Jan 25. doi: 10.1158/0008-5472.CAN-23-2557.
    PubMed     Abstract available


  33. ZHAO D, Verhaak RGW
    Defining the role of extrachromosomal DNA amplifications in medulloblastoma.
    Cancer Res. 2024 Jan 4. doi: 10.1158/0008-5472.CAN-23-4025.
    PubMed     Abstract available


    December 2023
  34. MALTA TM, Sabedot TS, Morosini NS, Datta I, et al
    The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-2093.
    PubMed     Abstract available


  35. WANG D, Yan K, Yu H, Li H, et al
    Fimepinostat impairs NF-kappaB and PI3K/AKT signaling and enhances gemcitabine efficacy in H3K27M-mutated diffuse intrinsic pontine glioma.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-0394.
    PubMed     Abstract available


    November 2023
  36. GUO X, Qiu W, Wang C, Qi Y, et al
    Neuronal activity promotes glioma progression by inducing proneural-to-mesenchymal transition in glioma stem cells.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-0609.
    PubMed     Abstract available


    September 2023
  37. YIN J, Seo Y, Rhim J, Jin X, et al
    Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells.
    Cancer Res. 2023 Sep 25. doi: 10.1158/0008-5472.CAN-22-3965.
    PubMed     Abstract available


    May 2023
  38. MONDAL I, Das O, Sun R, Gao J, et al
    PP2Ac Deficiency Enhances Tumor Immunogenicity by Activating STING-Type I Interferon Signaling in Glioblastoma.
    Cancer Res. 2023 May 23:CAN-22-3382. doi: 10.1158/0008-5472.CAN-22-3382.
    PubMed     Abstract available


  39. JACKSON ER, Duchatel RJ, Staudt DE, Persson ML, et al
    ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.
    Cancer Res. 2023 May 17:OF1-OF17. doi: 10.1158/0008-5472.CAN-23-0186.
    PubMed     Abstract available


  40. BAYIK D, Bartels CF, Lovrenert K, Watson DC, et al
    Correction: Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets.
    Cancer Res. 2023;83:1757.
    PubMed    


  41. JACKSON ER, Duchatel RJ, Staudt DE, Persson ML, et al
    ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.
    Cancer Res. 2023 May 5:CAN-23-0186. doi: 10.1158/0008-5472.CAN-23-0186.
    PubMed     Abstract available


    April 2023
  42. GUETTA-TERRIER C, Karambizi D, Akosman B, Zepecki JP, et al
    Chi3l1 is a modulator of glioma stem cell states and a therapeutic target in glioblastoma.
    Cancer Res. 2023 Apr 27:CAN-21-3629. doi: 10.1158/0008-5472.CAN-21-3629.
    PubMed     Abstract available


  43. MIRZAEI R, D'Mello C, Liu M, Nikolic A, et al
    Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells.
    Cancer Res. 2023 Apr 17:OF1-OF17. doi: 10.1158/0008-5472.CAN-22-3004.
    PubMed     Abstract available


  44. KARREMAN MA, Bauer AT, Solecki G, Berghoff AS, et al
    Active Remodeling of Capillary Endothelium via Cancer Cell-Derived MMP9 Promotes Metastatic Brain Colonization.
    Cancer Res. 2023;83:1299-1314.
    PubMed     Abstract available


    March 2023
  45. ZAMLER DB, Hu J
    Primitive Oligodendrocyte Precursor Cells Are Highly Susceptible to Gliomagenic Transformation.
    Cancer Res. 2023;83:807-808.
    PubMed     Abstract available


  46. PINE AR, Cirigliano SM, Singhania R, Nicholson J, et al
    Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution.
    Cancer Res. 2023 Mar 6:CAN-22-2872. doi: 10.1158/0008-5472.CAN-22-2872.
    PubMed     Abstract available


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