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  Neoplasms of the CNS

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20.10.2025

1 Acta Neuropathol
1 AJNR Am J Neuroradiol
1 BMC Cancer
1 BMC Neurol
2 Br J Cancer
1 Br J Neurosurg
2 Childs Nerv Syst
2 Clin Cancer Res
2 Int J Radiat Oncol Biol Phys
1 J Neurochem
19 J Neurooncol
1 J Neuropathol Exp Neurol
2 J Nucl Med
13 Neuro Oncol
1 Neurol Res
8 Neurosurgery
2 Oncogene
1 PLoS Biol
3 PLoS One
1 Radiol Imaging Cancer


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. PFAFF E, Schramm K, Blattner-Johnson M, Jones BC, et al
    Molecular characterization and clinical features of diffuse midline glioma in the pediatric precision oncology registry INFORM.
    Acta Neuropathol. 2025;150:42.
    PubMed         Abstract available


    AJNR Am J Neuroradiol

  2. GUO W, Lin L, Wu Y, Lin X, et al
    MRI-Based Quantification of Intratumoral Heterogeneity for Predicting Progression-Free Survival in Patients with Lung Cancer Brain Metastasis Receiving Radiotherapy.
    AJNR Am J Neuroradiol. 2025 Oct 16. doi: 10.3174/ajnr.A8869.
    PubMed         Abstract available


    BMC Cancer

  3. ZHANG Q, Xu J, Deng S, Li X, et al
    Efficacy of brain radiotherapy combined with atezolizumab and platinum-doublet chemotherapy for advanced non-small-cell lung cancer with brain metastases: a pooled analysis.
    BMC Cancer. 2025;25:1568.
    PubMed         Abstract available


    BMC Neurol

  4. ZHONG T, Chen X, Li Y, Chen Y, et al
    Preoperative prediction of brain invasion in meningiomas: a comparison of diffusion kurtosis imaging and diffusion tensor imaging.
    BMC Neurol. 2025;25:422.
    PubMed         Abstract available


    Br J Cancer

  5. ERJAN A, Jamora K, Gutierrez E, Santiago A, et al
    Correction: Cumulative incidence and survival outcomes of brain metastases in sarcoma: a large single center retrospective analysis.
    Br J Cancer. 2025 Oct 16. doi: 10.1038/s41416-025-03176.
    PubMed        

  6. FAN M, Wu X, Pan D, Du J, et al
    Multiscale Pancancer Analysis Uncovers Intrinsic Imaging and Molecular Characteristics Prominent in Breast Cancer and Glioblastoma.
    Br J Cancer. 2025 Oct 15. doi: 10.1038/s41416-025-03235.
    PubMed         Abstract available


    Br J Neurosurg

  7. LANNON M, Hart S, Martyniuk A, Sharma SV, et al
    From hope to loss and back again: loved ones' experience with glioblastoma in the spatial heterogeneity challenge.
    Br J Neurosurg. 2025 Oct 16:1-17. doi: 10.1080/02688697.2025.2569414.
    PubMed         Abstract available


    Childs Nerv Syst

  8. BASKURT O, Inan MA, Hicdonmez T
    Spinal capillary hemangioma with intramedullary and extramedullary extension in a child with cutaneous stigmata: a rare case.
    Childs Nerv Syst. 2025;41:312.
    PubMed         Abstract available

  9. MASTROPASQUA V, Rigante M, Massimi L, Frassanito P, et al
    Endoscopic endonasal transsphenoidal surgery in children: widening the spectrum of oncological indications in the pediatric age group.
    Childs Nerv Syst. 2025;41:311.
    PubMed         Abstract available


    Clin Cancer Res

  10. BAKHSHINYAN D, Custers S, Escudero L, Suk Y, et al
    Leveraging Medulloblastoma Clonal Dynamics to Overcome Treatment Resistance.
    Clin Cancer Res. 2025 Oct 15. doi: 10.1158/1078-0432.CCR-24-4010.
    PubMed         Abstract available

  11. MARIANI CL, Wachsmuth LP, Bramall AN, Meritet DM, et al
    Adapting Laser Interstitial Thermal Therapy for the Treatment of Naturally Occurring Intracranial Tumors in Dogs.
    Clin Cancer Res. 2025;31:4372-4382.
    PubMed         Abstract available


    Int J Radiat Oncol Biol Phys

  12. POTIRON S, Iturri L, Lamirault C, Dos Santos M, et al
    Dose Heterogeneity Reduces Radiation Oxygen Dependence in Both Tumor and Healthy Tissues: The Case of Proton Minibeam Radiation Therapy.
    Int J Radiat Oncol Biol Phys. 2025;123:1132-1145.
    PubMed         Abstract available

  13. JANAS A, Senger C, Krantchev K, Brandenburg S, et al
    Radiobiology and Radioresistance in High-Dose Radiosurgery for Brain Tumors: A Hypothesis-Generating Study Using an Intracranial Glioma Mouse Model.
    Int J Radiat Oncol Biol Phys. 2025 Oct 10:S0360-3016(25)06333.
    PubMed         Abstract available


    J Neurochem

  14. MUKHERJEE V, Yanamandra R, Rai N, Mahalingaswamy M, et al
    Coronin 1 Loss in Tumor Cells of Glioblastoma Patients Leads to Enhanced Tumor Aggressiveness.
    J Neurochem. 2025;169:e70261.
    PubMed         Abstract available


    J Neurooncol

  15. KOAY JM, Dion C, Michaelides L, Chaichana K, et al
    Cognitive impact of repeated surgical resections for the management of high-grade glioma.
    J Neurooncol. 2025;176:4.
    PubMed         Abstract available

  16. KIM E, Lee HI, Roh TH, Kim YZ, et al
    Hypofractionated vs. conventional fractionated radiotherapy in the temozolomide era for elderly patients with glioblastoma: a systematic review and meta-analysis by the Korean society for neuro-oncology.
    J Neurooncol. 2025;176:3.
    PubMed         Abstract available

  17. DAI X, He S, Qi Y, Li H, et al
    Predictive markers for molecular subtypes and WHO grade: T1rho-MRI in adult-type diffuse gliomas.
    J Neurooncol. 2025;176:6.
    PubMed         Abstract available

  18. GUZZINO J, Crompton DJ, Agarwal S, Kern S, et al
    Rapid early progression of glioblastoma: evaluation of a novel prognostic radiologic biomarker.
    J Neurooncol. 2025;176:5.
    PubMed         Abstract available

  19. ANDREOTTI A, Ferroni E, Guzzinati S, Baracco S, et al
    Incidence and survival of adult central nervous system tumors in the Veneto region: a population-based registry study (2016-2020).
    J Neurooncol. 2025;176:9.
    PubMed         Abstract available

  20. VAN DEN BERG L, Wilbers J, de Vos FYFL, van Kouwenhoven MCM, et al
    Chemotherapy in adult patients with pilocytic astrocytoma: a retrospective multicenter cohort study.
    J Neurooncol. 2025;176:7.
    PubMed         Abstract available

  21. NGUYEN TT, Pham TM, Quy PN, Chalise L, et al
    Premature mortality due to malignancies of the central nervous system in Japan: a nationwide descriptive analysis from 2000 to 2020.
    J Neurooncol. 2025;176:11.
    PubMed         Abstract available

  22. EL GHALBOUNI A, Snijders TJ, Amerein A, Tolboom N, et al
    Efficacy of Intra-arterial [(177)Lu]Lu-DOTATATE monotherapy for treatment-refractory meningioma.
    J Neurooncol. 2025;176:8.
    PubMed         Abstract available

  23. YUILE A, Wei JQ, McKelvey KJ, Colvin EK, et al
    Vaccine-induced immunity is maintained in glioma patients relative to other solid tumours.
    J Neurooncol. 2025;176:10.
    PubMed         Abstract available

  24. HONG S, Takami H, Umekawa M, Shinya Y, et al
    Systemic immune-inflammation index as a prognostic biomarker to predict overall survival after primary stereotactic radiosurgery for brain metastases.
    J Neurooncol. 2025;176:12.
    PubMed         Abstract available

  25. BHARDWAJ S, Singh J, Singh S, Roy C, et al
    Unveiling MMR deficiency in pediatric and AYA high-grade gliomas: insights from multiomic profiling.
    J Neurooncol. 2025;176:16.
    PubMed        

  26. JHANDI S, Goold E, Jensen RL
    Meningioma grade and molecular markers of proliferation, hypoxia, and vascularity as predictors of outcome in a cohort with long-term patient follow-up.
    J Neurooncol. 2025;176:18.
    PubMed         Abstract available

  27. NECHAEVA A, Ulitin A, Sitovskaya D, Yudintceva N, et al
    Fluorescence molecular imaging of high-grade gliomas and brain metastases using the RAS70 peptide targeting plasma membrane-bound Hsp70 on tumor cells.
    J Neurooncol. 2025;176:15.
    PubMed         Abstract available

  28. BASELGA M, Berna S, Perez VMM, Soriano M, et al
    Three-dimensional ultrastructural analysis of glioblastoma reveals spheresome-mediated intercellular communication.
    J Neurooncol. 2025;176:23.
    PubMed        

  29. ROUX A, Tauziede-Espariat A, Simboli GA, Elia A, et al
    High-grade glioma, IDH- and H3-wildtype in young adults: a rare condition with a distinct epigenetic landscape.
    J Neurooncol. 2025;176:22.
    PubMed         Abstract available

  30. GOULENKO V, Sinha S, Madhugiri VS, Almeida ND, et al
    Modulating the pace: systemic targeted therapy, brain metastasis velocity, and outcomes after Gamma Knife radiosurgery in breast cancer brain metastases.
    J Neurooncol. 2025;176:21.
    PubMed        

  31. DASGUPTA P, Dagher SA, Chi X, Soomro Z, et al
    Genomic determinants of the diffusely infiltrative gliomatosis cerebri phenotype.
    J Neurooncol. 2025;176:19.
    PubMed        

  32. HARLAY V, Bequet C, Appay R, Bertucci A, et al
    Autonomy duration in patients with biopsy-only unresectable IDH wild-type glioblastomas.
    J Neurooncol. 2025;176:20.
    PubMed         Abstract available

  33. VAZIRI T, Liu IC, Bettegowda C, Croog V, et al
    Stereotactic radiosurgery for patients with extensive brain metastases across the disease course.
    J Neurooncol. 2025;176:24.
    PubMed         Abstract available


    J Neuropathol Exp Neurol

  34. MURAYI R, El-Abtah M, Ejikeme T, Xiao T, et al
    Validation of an immunohistochemistry-based molecular group stratification of intracranial meningiomas.
    J Neuropathol Exp Neurol. 2025 Oct 15:nlaf120. doi: 10.1093.
    PubMed         Abstract available


    J Nucl Med

  35. CHEN WC, Raleigh DR
    Rational Radionuclide Therapy for Recurrent Meningioma.
    J Nucl Med. 2025 Oct 16:jnumed.125.270775. doi: 10.2967/jnumed.125.270775.
    PubMed        

  36. TOLBOOM N, Albert NL, Braat AJAT, Snijders TJ, et al
    From Compassionate Use Toward High-Level Evidence for Radiopharmaceutical Therapy in Recurrent Meningioma: The LUMEN-1 and MOMENTUM-1 Trials.
    J Nucl Med. 2025 Oct 16:jnumed.125.270820. doi: 10.2967/jnumed.125.270820.
    PubMed        


    Neuro Oncol

  37. ZHANG W, Grams MP, Oberoi RK, Oh JH, et al
    The impact of therapeutic radiation on drug distribution across the blood-brain barrier in normal mouse brain and orthotopic glioblastoma tumors.
    Neuro Oncol. 2025;27:2250-2261.
    PubMed         Abstract available

  38. SCHIFF D, Ye X, Li J, Ellingson BM, et al
    Phase I/II and Window-of-Opportunity Study of Pamiparib and Metronomic Temozolomide for Recurrent IDH Mutant Gliomas.
    Neuro Oncol. 2025 Oct 16:noaf246. doi: 10.1093.
    PubMed         Abstract available

  39. FALCO-ROGET J, Antonio Basile G, Janus A, Lillo S, et al
    A non-local diffusion magnetic resonance imaging tract density biomarker to stratify, predict, and interpret survival rates in human glioblastoma.
    Neuro Oncol. 2025 Oct 11:noaf234. doi: 10.1093.
    PubMed         Abstract available

  40. BARTHEL FP
    Uncommon Territory: The Clinical and Molecular Profile of Metastatic Gliomas.
    Neuro Oncol. 2025 Oct 15:noaf244. doi: 10.1093.
    PubMed        

  41. PRICE M, Ballard CAP, Benedetti JR, Kruchko C, et al
    CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2018-2022.
    Neuro Oncol. 2025;27.
    PubMed         Abstract available

  42. LAMBA N, Kraemer L, Rahman R, Tanguturi S, et al
    Characterization of Focal Leptomeningeal Extension in Patients with Brain Metastases: A Novel Entity.
    Neuro Oncol. 2025 Oct 11:noaf229. doi: 10.1093.
    PubMed         Abstract available

  43. MIGLIORINI D
    CAR T cell therapy for meningioma: mesothelin emerges as a novel promising target.
    Neuro Oncol. 2025 Oct 11:noaf240. doi: 10.1093.
    PubMed        

  44. HAGIWARA A, Uchida W, Ozawa T, Takabayashi K, et al
    Contralateral Neurofluid Dynamics Predict Survival in IDH Wild-type Glioblastoma: A DTI-ALPS and Free Water Imaging Study.
    Neuro Oncol. 2025 Oct 11:noaf242. doi: 10.1093.
    PubMed         Abstract available

  45. LASICA AB, Lan Z, Miller JJ, Jiao A, et al
    Clinical, molecular, and radiological predictors of prognosis in newly diagnosed astrocytoma, IDH-mutant, WHO grade 4.
    Neuro Oncol. 2025;27:2382-2398.
    PubMed         Abstract available

  46. VAN DEN BENT MJ, Vogelbaum MA, Cloughesy T, Galldiks N, et al
    Response Assessment in Neuro-Oncology (RANO) 2009-2025: Broad scope and implementation-A progress report.
    Neuro Oncol. 2025;27:2209-2224.
    PubMed         Abstract available

  47. BELAKHOUA S, Vasudevaraja V, Schroff C, Galbraith K, et al
    DNA methylation profiling of pituitary neuroendocrine tumors identifies distinct clinical and pathological subtypes based on epigenetic differentiation.
    Neuro Oncol. 2025;27:2341-2354.
    PubMed         Abstract available

  48. ASOGWA OA, Dirven L, Walbert T, Armstrong TS, et al
    Establishing the content validity of patient-reported outcome measures used in neuro-oncology based on the WHO ICF framework: Part of the RANO-PRO initiative.
    Neuro Oncol. 2025;27:2399-2414.
    PubMed         Abstract available

  49. LUNING R, French PJ, Vanbilloen WJF, Dobber L, et al
    T cell immunity in glioma and potential implications for immunotherapy: a systematic review.
    Neuro Oncol. 2025 Oct 17:noaf236. doi: 10.1093.
    PubMed         Abstract available


    Neurol Res

  50. HE G, Huang J, Zeng Z, Zheng Z, et al
    Identification of taurine metabolism related subtypes in gliomas and construction of risk models to predict prognosis and immune microenvironment.
    Neurol Res. 2025 Oct 16:1-17. doi: 10.1080/01616412.2025.2574353.
    PubMed         Abstract available


    Neurosurgery

  51. MACLEAN MA, Ahmad S, Hebb ALO, Tahir A, et al
    Intracavitary Yttrium-90 Colloid Therapy for Cystic Sellar Masses: A Phase II Clinical Trial With 5-Year Follow-Up.
    Neurosurgery. 2025 Apr 23. doi: 10.1227/neu.0000000000003460.
    PubMed         Abstract available

  52. TANG A, Abdallah HM, Gardner PA, Zenonos GA, et al
    Factors Associated With a Higher 30-Day Hospitalization Period for Pituitary Adenoma Patients: Introducing a Novel Outcome Metric.
    Neurosurgery. 2025 Apr 30. doi: 10.1227/neu.0000000000003471.
    PubMed         Abstract available

  53. GOYAL-HONAVAR A, Kumar A C, Dwarakanath S, Konar S, et al
    Factors Affecting Long-Term Pain Control After Gamma Knife Radiosurgery in Secondary Tumor-Related Trigeminal Neuralgia.
    Neurosurgery. 2025 May 9. doi: 10.1227/neu.0000000000003503.
    PubMed         Abstract available

  54. RAUB SL, Fixman B, Hanks T, Nistal D, et al
    Surgical Outcomes of Silent ACTH+ Corticotroph Pituitary Neuroendocrine Tumors: A Multi-Institutional Experience and Review of the Literature.
    Neurosurgery. 2025 May 15. doi: 10.1227/neu.0000000000003512.
    PubMed         Abstract available

  55. ALMEIDA ND, Schrand TV, Madhugiri V, Fang M, et al
    Early Initiation of Radiation Therapy Improves Survival in Elderly Patients With Glioblastoma.
    Neurosurgery. 2025 Oct 13. doi: 10.1227/neu.0000000000003768.
    PubMed         Abstract available

  56. SKJOTH-RASMUSSEN J, Kjaer A
    In Reply: Novel Urokinase-Type Plasminogen Activator Receptor-Targeting Optical Imaging Agent ICG-Glu-Glu-AE105 for Visualization of Malignant Glioma During Surgery: First-in-Human Study in 35 Patients With Brain Cancer.
    Neurosurgery. 2025 Oct 14. doi: 10.1227/neu.0000000000003805.
    PubMed        

  57. RAHMAN MM
    Letter: Novel Urokinase-Type Plasminogen Activator Receptor-Targeting Optical Imaging Agent ICG-Glu-Glu-AE105 for Visualization of Malignant Glioma During Surgery: First-in-Human Study in 35 Patients With Brain Cancer.
    Neurosurgery. 2025 Oct 14. doi: 10.1227/neu.0000000000003804.
    PubMed        

  58. MUIR MT, Noll K, Traylor JI, Patel R, et al
    Resectability of White Matter Tracts in Patients With Language-Critical Gliomas.
    Neurosurgery. 2025 Oct 15. doi: 10.1227/neu.0000000000003792.
    PubMed         Abstract available


    Oncogene

  59. YANG T, Zeng Y, Li Y, Huang Y, et al
    Par6/SOX2 interact to modulate stemness maintenance in glioma by regulating the EGFR/PI3K/AKT signaling cascade.
    Oncogene. 2025 Oct 11. doi: 10.1038/s41388-025-03595.
    PubMed         Abstract available

  60. FAN X, Yang Y, Li X, Yu L, et al
    BRD4 inhibition sensitizes glioblastoma to radiotherapy by suppressing super-enhancer-driven COL1A1.
    Oncogene. 2025 Oct 14. doi: 10.1038/s41388-025-03596.
    PubMed         Abstract available


    PLoS Biol

  61. GHOSH M, Pilanc-Kudlek P, Baluszek S, Jacek K, et al
    Identification and characterization of tumor-associated astrocyte subpopulations and their interactions with the tumor microenvironment in experimental glioblastomas.
    PLoS Biol. 2025;23:e3002893.
    PubMed         Abstract available


    PLoS One

  62. MUSTHAFA N, Masud MM, Memon Q, Farhad M, et al
    VISION: View-specific integrated segmentation-classification framework for accurate brain tumor detection in MRI scans.
    PLoS One. 2025;20:e0332395.
    PubMed         Abstract available

  63. MARSHALL KL, Meadows E, Mizener A, Hollander JM, et al
    Differential bioenergetic profile of human glioblastoma following transplantation of myocyte-derived mitochondria.
    PLoS One. 2025;20:e0330322.
    PubMed         Abstract available

  64. LESER C, Kabashi F, Dorffner G, Zaric O, et al
    Exploring the role of routine brain imaging in detecting asymptomatic brain metastases in first diagnosed HER2-positive breast cancer.
    PLoS One. 2025;20:e0334610.
    PubMed         Abstract available


    Radiol Imaging Cancer

  65. RAI P, Mehta T, Kumar SS, Choi R, et al
    Metastatic Meningioma: Neuroradiologic and Molecular Imaging Perspectives.
    Radiol Imaging Cancer. 2025;7:e250265.
    PubMed         Abstract available


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