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  Neoplasms of the CNS

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05.01.2026

4 BMC Cancer
1 BMC Neurol
1 Cancer Res
2 Childs Nerv Syst
1 Eur J Cancer
1 Int J Cancer
2 Int J Radiat Oncol Biol Phys
14 J Neurooncol
1 J Neuropathol Exp Neurol
4 Neuro Oncol
1 Neuroradiology
2 Neurosurgery
5 PLoS One
2 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    BMC Cancer

  1. CHEN H, Liang W, Li Z, Bian C, et al
    Prognostic value of LPAR1 expression and methylation in low-grade gliomas: a meta-analysis of TCGA and CGGA datasets and functional validation.
    BMC Cancer. 2025 Dec 30. doi: 10.1186/s12885-025-15406.
    PubMed         Abstract available

  2. WANG J, Wang C, Sun Z, Zhang A, et al
    CXCL8-dependent recruitment of neutrophils by the tumor microenvironment drives poor prognosis in glioblastoma patients.
    BMC Cancer. 2025 Dec 26. doi: 10.1186/s12885-025-14698.
    PubMed        

  3. BAI H, Liu Y, Ji C, Zhang Q, et al
    Mutation patterns and prognostic potentiality of homologous recombination repair genes in gliomas.
    BMC Cancer. 2025;25:1884.
    PubMed         Abstract available

  4. LIU J, Chen J, Chen L, Wang Y, et al
    Integrated single-cell and transcriptome sequencing data reveal the value of AOC1 in gliomas tumor microenvironment and prognosis.
    BMC Cancer. 2025 Dec 22. doi: 10.1186/s12885-025-15457.
    PubMed        


    BMC Neurol

  5. LI R, Zhang Z, Zhang X, Song J, et al
    Identification of distinct symptom profiles in primary brain tumor patients: a prospective longitudinal study.
    BMC Neurol. 2025 Dec 26. doi: 10.1186/s12883-025-04595.
    PubMed         Abstract available


    Cancer Res

  6. KRATTLI RP JR, Do AH, El-Khatib SM, Alikhani L, et al
    C5aR1 Inhibition Alleviates Cranial Radiation-Induced Cognitive Decline.
    Cancer Res. 2026;86:255-272.
    PubMed         Abstract available


    Childs Nerv Syst

  7. CAMPINO GA, Shrot S, Constantini S, Roth J, et al
    Significant clinical and radiologic response to targeted therapy in pediatric cervicomedullary low-grade gliomas harboring the BRAFV600E mutation.
    Childs Nerv Syst. 2025;41:429.
    PubMed         Abstract available

  8. STEPNIAK A, Diamandi J, Shanahan RM, Garcia J, et al
    Mapping influence in pediatric craniopharyngioma: the 50 most cited articles.
    Childs Nerv Syst. 2025;41:432.
    PubMed         Abstract available


    Eur J Cancer

  9. ISLAM MT, Yang F, Komladzei S, Akhter M, et al
    Integrative machine learning reveals hidden and emerging co-regulatory gene networks for multi-phase glioblastoma outcome prediction.
    Eur J Cancer. 2025;234:116197.
    PubMed         Abstract available


    Int J Cancer

  10. MUELLER T, Vasella F, Velz J, Voglis S, et al
    Conditional survival in glioblastoma: The evolution of prognostic factors over time.
    Int J Cancer. 2025 Dec 30. doi: 10.1002/ijc.70285.
    PubMed         Abstract available


    Int J Radiat Oncol Biol Phys

  11. MENG J, Zhang L, Chen J, Shi W, et al
    A prospective phase II trial of hypofractionated stereotactic radiotherapy (FSRT) for patients with 1-10 brain metastases from breast cancer.
    Int J Radiat Oncol Biol Phys. 2025 Dec 24:S0360-3016(25)06606.
    PubMed         Abstract available

  12. MA J, Yu H, Zhang X, Yuan J, et al
    Skull Dosimetry for Mitigating Acute Hematologic Toxicity in NSCLC Patients with Brain Metastases Undergoing Cranial Radiotherapy and Immunotherapy.
    Int J Radiat Oncol Biol Phys. 2025 Dec 24:S0360-3016(25)06623.
    PubMed         Abstract available


    J Neurooncol

  13. HUANG G, Wei Y, Hou X, Jia X, et al
    ANG peptide-modified exosomes loaded with oleanolic acid target GPX4 for enhanced breast cancer brain metastasis therapy.
    J Neurooncol. 2025;176:130.
    PubMed        

  14. BELLOMO J, Gonel M, Sutter J, Zeitlberger AM, et al
    Postoperative absence of residual intracranial tumor volume is associated with improved survival and intracranial disease control in non-small cell lung cancer brain metastases.
    J Neurooncol. 2025;176:131.
    PubMed         Abstract available

  15. EVERS SMITH JW, Alzate JD, Power L, Wei W, et al
    The impact of the molecular and genetic properties of glioblastoma on patient outcomes following stereotactic radiosurgery at recurrence.
    J Neurooncol. 2025;176:132.
    PubMed        

  16. AMIRKHANI N, Maroufi F, Pour-Rashidi A, Shirani M, et al
    Impact of anti-seizure medication duration on postoperative seizures following supratentorial high-grade glioma resection: a mixed-model and tree-based approach.
    J Neurooncol. 2025;176:134.
    PubMed         Abstract available

  17. RON GN, Ron IG, Kantor H, Fening E, et al
    Effect of combining targeted therapies or chemotherapy with stereotactic radiosurgery (SRS) on the prognosis of patients with brain metastases from non-small cell lung cancer (NSCLC).
    J Neurooncol. 2025;176:135.
    PubMed         Abstract available

  18. KITE T, Wegner RE, Shepard MJ
    Comment on: "Neoadjuvant gamma knife surgery for metastatic brain tumor: clinical use and impact on leptomeningeal seeding".
    J Neurooncol. 2025;176:146.
    PubMed        

  19. KERIC N, Krenzlin H, Lange F, Dauth A, et al
    Treatment differences in IDH-wildtype glioma - the impact of surgery and adjuvant therapy.
    J Neurooncol. 2025;176:145.
    PubMed         Abstract available

  20. JEUNG YS, Lee WT, Kim Y, Keam B, et al
    Documented advance care planning elements and end-of-life care patterns in malignant glioma vs. major solid tumors: a single-center retrospective study.
    J Neurooncol. 2025;176:142.
    PubMed         Abstract available

  21. CROUZEN J, Mast M, Kerkhof M, Vos M, et al
    Paradigm shift in patients with multiple brain metastases from whole brain radiotherapy to high precision multimodality treatment including stereotactic radiotherapy.
    J Neurooncol. 2025;176:139.
    PubMed         Abstract available

  22. ST BRICE K, Parker T, Wouters K, Guzman-Rios ED, et al
    Extent of resection and adjuvant treatment in adult cerebellar glioblastoma: systematic review and meta-analysis of survival outcomes.
    J Neurooncol. 2025;176:138.
    PubMed         Abstract available

  23. KIM J, Shin K, Lee A, Lee J, et al
    Prognostic impact of endocrine therapy and BDNF-TrkB axis in breast cancer brain metastases.
    J Neurooncol. 2025;176:140.
    PubMed         Abstract available

  24. MORAES FCA, Rodrigues PB, Vital LDS, Talah BAD, et al
    Prevalence of human cytomegalovirus in glioblastoma multiforme: a systematic review and meta-analysis.
    J Neurooncol. 2025;176:143.
    PubMed        

  25. LIU J, Ha JH, Abikenari M, Sjoholm MA, et al
    Adaptive immunotherapeutic paradigms in diffuse midline glioma: integrating epigenetic reprogramming, neuron-glioma interactions, and tumor microenvironment modulation.
    J Neurooncol. 2025;176:144.
    PubMed         Abstract available

  26. NAHLS NS, Anttonen A, Kitti P, Leskela RL, et al
    Early palliative care decision in patients with primary brain tumor reduces emergency department visits and hospitalization at the end of life.
    J Neurooncol. 2025;176:137.
    PubMed         Abstract available


    J Neuropathol Exp Neurol

  27. FUKUOKA K, Irikura T, Kanemura Y, Hirato J, et al
    Intratumoral heterogeneity of MYC status and methylation subtyping in group 3 medulloblastoma: A case report.
    J Neuropathol Exp Neurol. 2025 Dec 23:nlaf153. doi: 10.1093.
    PubMed        


    Neuro Oncol

  28. CSELENYI Z, Jucaite A, Stragliotto G, Bartek J, et al
    Subtype selective PET imaging of PARP1 binding in non-human primates, healthy volunteers and patients with glioblastoma using [11C]AZ14193391.
    Neuro Oncol. 2025 Dec 23:noaf290. doi: 10.1093.
    PubMed         Abstract available

  29. DING Y, Zhan Q, Cui L, Cui X, et al
    VITA-GBM: EPIC-0502-Driven HIF1alpha Degradation Overcomes Bevacizumab Resistance and Synergizes with TMZ in Glioblastoma.
    Neuro Oncol. 2025 Dec 31:noaf293. doi: 10.1093.
    PubMed         Abstract available

  30. AGGARWAL A, Youngblood MW, Picart T, Najem H, et al
    Meningioma cell reprogramming and microenvironment interactions underlie brain invasion.
    Neuro Oncol. 2025 Dec 31:noaf292. doi: 10.1093.
    PubMed         Abstract available

  31. SCHECK JG, Boztepe B, Kernbach JM, Karimian-Jazi K, et al
    Multimodality mapping of immunotherapy distribution as a predictive marker in glioma.
    Neuro Oncol. 2025 Dec 31:noaf295. doi: 10.1093.
    PubMed         Abstract available


    Neuroradiology

  32. KIKUCHI K, Togao O, Yamashita K, Momosaka D, et al
    Relaxometry assessment of meningioma consistency using quantitative magnetic resonance imaging.
    Neuroradiology. 2025 Dec 29. doi: 10.1007/s00234-025-03879.
    PubMed         Abstract available


    Neurosurgery

  33. FERREIRA MY, Cardoso LJC, Ben-Shalom N
    Letter: Integrated Clinical Genetic Analysis of Meningiomas Causing Bony Hyperostosis Shows More Severe Clinical Course and Overexpression of Secreted Pro-Osteogenic Factors.
    Neurosurgery. 2025 Dec 24. doi: 10.1227/neu.0000000000003891.
    PubMed        

  34. MCDONALD MF, Khan AB, Patel AJ
    In Reply: Letter: Integrated Clinical Genetic Analysis of Meningiomas Causing Bony Hyperostosis Shows More Severe Clinical Course and Overexpression of Secreted Pro-Osteogenic Factors.
    Neurosurgery. 2025 Dec 24. doi: 10.1227/neu.0000000000003892.
    PubMed        


    PLoS One

  35. LEE J, Chung H, Suh M, Lee JH, et al
    Deep learning for deep learning performance: How much data is needed for segmentation in biomedical imaging?
    PLoS One. 2025;20:e0339064.
    PubMed         Abstract available

  36. LAAJAVA J, Niemela M, Korja M
    Prevalence and associating factors for iatrogenic gliosis-like changes in surgically treated intracranial meningioma patients-A retrospective study of 255 meningioma patients.
    PLoS One. 2025;20:e0339857.
    PubMed         Abstract available

  37. LIU S, Xie Y, Gong X, He J, et al
    Machine learning-based prediction of glioma grading.
    PLoS One. 2025;20:e0314831.
    PubMed         Abstract available

  38. TOMITA Y, Link G, Ge Y, Gold ERH, et al
    Effects of combination therapy of a CDK4/6 and MEK inhibitor in diffuse midline glioma preclinical models.
    PLoS One. 2025;20:e0323235.
    PubMed         Abstract available

  39. GRIFFITHS-KING D, Mulvany T, Rose H, Novak J, et al
    Ratio maps of T1w/T2w MRI signal intensity do not improve deep-learning segmentation of pediatric brain tumors.
    PLoS One. 2025;20:e0323398.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  40. ZARODNIUK M, Wenninger A, Najera J, Lee J, et al
    Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans.
    Proc Natl Acad Sci U S A. 2026;123:e2513172122.
    PubMed         Abstract available

  41. KAANOGLU H, Akyel YK, Adefolaju A, Valdivia A, et al
    Combinatorial treatment of glioblastoma with temozolomide (TMZ) plus 5-ethynyl-2'-deoxyuridine (EdU).
    Proc Natl Acad Sci U S A. 2026;123:e2532187123.
    PubMed         Abstract available


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