Home The Word Brain	My Amedeo FAQ Privacy About
	Amedeo C49 English + 你好 (nǐ hǎo) = limitless possibilities. Start learning Mandarin Chinese today—for free, forever. Amedeo C49 is completely free, for life. Next week: +49.

Neoplasms of the CNS

Free Subscription 25.08.2025 1 Acta Neuropathol 1 AJNR Am J Neuroradiol 4 BMC Cancer 1 Br J Neurosurg 4 Childs Nerv Syst 2 Clin Cancer Res 1 Eur J Cancer 2 Int J Cancer 1 Int J Radiat Oncol Biol Phys 2 J Clin Oncol 18 J Neurooncol 1 J Neurosurg 6 Neuro Oncol 2 Neurology 6 Neuroradiology 4 Neurosurgery 1 Oncogene 2 Proc Natl Acad Sci U S A

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Acta Neuropathol

1. WEBER KJ, Dettki M, Munzberg M, Zeiner PS, et al
   DNA methylation analysis reveals an epigenetic signature distinctive of high-grade oligodendroglioma.
   Acta Neuropathol. 2025;150:21.
   PubMed         Abstract available
   
   

   
   AJNR Am J Neuroradiol

2. HAN Y, Cui Z, Hu W, Cao X, et al
   Similarity of Biological Information Captured by (68)Ga-PSMA-11 PET and ASL Perfusion MRI in Glioblastoma.
   AJNR Am J Neuroradiol. 2025 Aug 21:ajnr.A8965. doi: 10.3174/ajnr.A8965.
   PubMed         Abstract available
   
   

   
   BMC Cancer

3. ZHANG F, Liu X
   Inhibition of c-Abl suppresses the proliferation, invasion and migration of glioma cells.
   BMC Cancer. 2025;25:1330.
   PubMed         Abstract available
   
   
4. TAIWO R, Harary PM, Trinh TTH, Granucci M, et al
   Adaptive cohort design and LAT1 expression scale: study protocol for a Phase 2a trial of QBS72S in breast cancer brain metastases.
   BMC Cancer. 2025;25:1316.
   PubMed         Abstract available
   
   
5. ROY ME, Zgheib A, Eliopoulos N, Annabi B, et al
   A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistance.
   BMC Cancer. 2025;25:1348.
   PubMed         Abstract available
   
   
6. MILLER AR, Shah T, Strawser CN, Rivaldi A, et al
   MRD4U: A path to development for personalized liquid biopsy for children with central nervous system tumors.
   BMC Cancer. 2025;25:1365.
   PubMed         Abstract available
   
   

   
   Br J Neurosurg

7. SHAIKH ST, Pattankar S, Nambiar R, Sahibzada H, et al
   Surgical outcomes for brain metastases: focused analysis of multiple metastases and recurrent metastases following stereotactic radiosurgery.
   Br J Neurosurg. 2025 Aug 22:1-10. doi: 10.1080/02688697.2025.2548400.
   PubMed         Abstract available
   
   

   
   Childs Nerv Syst

8. MILISAVLJEVIC F, Bogdanovic I, Miljkovic A, Milin-Lazovic J, et al
   Supracerebellar highway-fast and safe road to pediatric pineal tumor resection.
   Childs Nerv Syst. 2025;41:260.
   PubMed         Abstract available
   
   
9. LU VM, Jallo GI, Shimony N
   Pediatric low-grade brainstem glioma: a review of current diagnosis and treatment paradigms in the molecular era.
   Childs Nerv Syst. 2025;41:261.
   PubMed         Abstract available
   
   
10. ABBASSY M, Enayet A, Elbaroody M, Atallah A, et al
    Predictive factors in the management of hydrocephalus and cerebrospinal fluid-related complications in pediatric choroid plexus tumors: a single-center experience.
    Childs Nerv Syst. 2025;41:264.
    PubMed         Abstract available
    
    
11. PALAVANI LB, Borges PGLB, Semione G, Ferreira MY, et al
    Proton versus photon radiation therapy for pediatric medulloblastomas: a systematic review and meta-analysis.
    Childs Nerv Syst. 2025;41:266.
    PubMed         Abstract available
    
    

    
    Clin Cancer Res

12. FENG Y, Haupt B, Huynh TT, Meshaw R, et al
    Longitudinal Imaging Reveals Tumor Uptake and Prolonged Retention of Bispecific T Cell-Engaging Antibody in GBM via Passive and Active Mechanisms.
    Clin Cancer Res. 2025;31:3537-3549.
    PubMed         Abstract available
    
    
13. HABASHY KJ, Synold TW, Feng Y, Gomez C, et al
    Pharmacokinetic Analysis of Carboplatin and Fluorescein Brain Retention following Ultrasound-Based Blood-Brain Barrier Opening.
    Clin Cancer Res. 2025;31:3562-3570.
    PubMed         Abstract available
    
    

    
    Eur J Cancer

14. MCCABE M, Rossi S, Cerza F, Massimino M, et al
    Survival of European adolescents and young adults diagnosed with central nervous system tumours and comparison with younger and older age groups: EUROCARE-6 results.
    Eur J Cancer. 2025;227:115661.
    PubMed         Abstract available
    
    

    
    Int J Cancer

15. HEMMINGSEN CH, Kjaer SK, Hjorth S, Norby U, et al
    Maternal hormonal contraceptive use and childhood central nervous system tumor risk in a large Scandinavian cohort.
    Int J Cancer. 2025 Jun 5. doi: 10.1002/ijc.35509.
    PubMed         Abstract available
    
    
16. ALHALABI OT, Klein L, Wasilewski D, Mellal A, et al
    Managing hydrocephalus in patients with leptomeningeal disease: A multicenter retrospective analysis.
    Int J Cancer. 2025;157:1613-1624.
    PubMed         Abstract available
    
    

    
    Int J Radiat Oncol Biol Phys

17. FLEMING JL, Pugh SL, Chang SM, McElroy JP, et al
    Comprehensive Molecular Analysis in NRG Oncology/RTOG 9813: A Phase 3 Study of Radiation and Temozolomide Versus Radiation and BCNU/CCNU in Anaplastic Astrocytoma.
    Int J Radiat Oncol Biol Phys. 2025;123:84-92.
    PubMed         Abstract available
    
    

    
    J Clin Oncol

18. PEROL M, Li W, Lai RK, Zhou C, et al
    Reply to: "Baseline Brain Metastasis Imbalance in TRUST: Implications for Interpreting Intracranial Efficacy of Taletrectinib" and "Taletrectinib in ROS1 Fusion-Positive Non-Small Cell Lung Cancer: Promising Yet Premature?".
    J Clin Oncol. 2025 Aug 21:JCO2501448. doi: 10.1200/JCO-25-01448.
    PubMed        
    
    
19. HUANG J
    Baseline Brain Metastasis Imbalance in TRUST: Implications for Interpreting Intracranial Efficacy of Taletrectinib.
    J Clin Oncol. 2025 Aug 21:JCO2500967. doi: 10.1200/JCO-25-00967.
    PubMed        
    
    

    
    J Neurooncol

20. RAMMELOO E, Young JS, Schouten JW, Bos EM, et al
    Preoperative assessment of tumor eloquence and resectability: an international survey.
    J Neurooncol. 2025;175:47-59.
    PubMed         Abstract available
    
    
21. SHAH KH, Khalafallah AM, Knott MV, Berke CN, et al
    Predictors of prolonged length of stay in patients undergoing laser interstitial thermal therapy for intracranial tumors.
    J Neurooncol. 2025;175:91-99.
    PubMed         Abstract available
    
    
22. BECKHAM TH, Cha EE, Rooney MK, Tom MC, et al
    Cesium-131 collagen tile brachytherapy for salvage of recurrent intracranial metastases.
    J Neurooncol. 2025;175:165-174.
    PubMed         Abstract available
    
    
23. ORSMOND A, De Sousa SMC, McCormack A
    The landscape of germline variants in breast and colorectal cancer susceptibility genes in patients with pituitary tumours.
    J Neurooncol. 2025;175:379-388.
    PubMed         Abstract available
    
    
24. GENSLER R, Xia Y, Horowitz MA, Abdulrahim M, et al
    Outcomes of leptomeningeal disease after only vertebral osseous metastases: a real-world analysis using the TriNetX database.
    J Neurooncol. 2025;175:219-229.
    PubMed         Abstract available
    
    
25. IVREN M, Yalman D, Ishak B, Ille S, et al
    Beyond surgical radicality in intramedullary spinal cord metastases: neurological function and systemic disease burden drive patient outcomes.
    J Neurooncol. 2025;175:431-442.
    PubMed         Abstract available
    
    
26. ARENDT CT, Lohlau M, Roder L, Burger MC, et al
    Susceptibility- and T2*-weighted MRI features of CNS large B-cell lymphoma in a large single-center cohort: prevalence, patterns, and clinical associations.
    J Neurooncol. 2025;175:231-241.
    PubMed         Abstract available
    
    
27. SARIKAYA C, Yaltirik CK, Varol E, Yuvruk E, et al
    The role of MRI patterns in predicting neurologic deficits in spinal ependymomas.
    J Neurooncol. 2025;175:313-322.
    PubMed         Abstract available
    
    
28. ABIKENARI M, Liu J, Ha JH, Annagiri S, et al
    Emerging trends in cell-based therapies: contemporary advances and ethical considerations in translational neurosurgical oncology.
    J Neurooncol. 2025;175:1-20.
    PubMed         Abstract available
    
    
29. WEI CZ, Deng H, Ashwat E, Albano L, et al
    Tumor control and motor function in patients with metastases located in the primary motor cortex after stereotactic radiosurgery.
    J Neurooncol. 2025;175:63-70.
    PubMed         Abstract available
    
    
30. CHEN W, Yuan J, Liu G, Cui L, et al
    Metagenomic next-generation sequencing and chromosomal copy number variation analysis in cerebrospinal fluid for the detection of meningeal carcinomatosis.
    J Neurooncol. 2025;175:175-181.
    PubMed         Abstract available
    
    
31. DAS S, Walker-Dilks C, Nicholas G, Sahgal A, et al
    Executive summary of organizational guidance for the care of patients with central nervous system tumours in Ontario: consensus recommendations.
    J Neurooncol. 2025;175:419-429.
    PubMed         Abstract available
    
    
32. YOGENDRAN LV, Kareddy A, Abbas SO, Scharf Z, et al
    Effects of re-challenge with temozolomide in grade 2/3 IDH mutant gliomas at first progression.
    J Neurooncol. 2025 Aug 20. doi: 10.1007/s11060-025-05087.
    PubMed         Abstract available
    
    
33. ARACELI T, Haj A, Doenitz C, Stoerr EM, et al
    Complete resection of brain metastases - when does it matter?
    J Neurooncol. 2025 Aug 22. doi: 10.1007/s11060-025-05193.
    PubMed         Abstract available
    
    
34. SHIH JJ, Jain B, Patel R, Jain U, et al
    Stereotactic radiosurgery for brain metastases: evolving practice patterns from the national cancer database (2004-2020).
    J Neurooncol. 2025 Aug 22. doi: 10.1007/s11060-025-05178.
    PubMed        
    
    
35. GIORDANO C, Sassu CM, Marchetti C, Guerri G, et al
    Brain metastases from ovarian cancer: neuroradiological profile and survival overview of neurosurgical cases.
    J Neurooncol. 2025 Aug 21. doi: 10.1007/s11060-025-05192.
    PubMed         Abstract available
    
    
36. WANG CY, Lin CF, Yang HC, Liu CY, et al
    Gamma knife radiosurgery for breast cancer brain metastasis: survival outcomes, prognotic factors, and the role of repeat treatment.
    J Neurooncol. 2025 Aug 21. doi: 10.1007/s11060-025-05188.
    PubMed         Abstract available
    
    
37. LIN CA, Lin C, Rhodes CT, Moseley MC, et al
    Takeaways from meta-analysis: indications of combinational treatments for glioblastoma.
    J Neurooncol. 2025 Aug 21. doi: 10.1007/s11060-025-05205.
    PubMed         Abstract available
    
    

    
    J Neurosurg

38. CAN A, Giotta Lucifero A, Brettler A, Almefty K, et al
    Surgery of peritorcular meningiomas: the structural basis for preservation of torcular venous flow.
    J Neurosurg. 2025 Aug 15:1-9. doi: 10.3171/2025.4.JNS25359.
    PubMed         Abstract available
    
    

    
    Neuro Oncol

39. KALEY TJ, Grommes C, Coffee E, Young RJ, et al
    Multicenter basket trial for Central Nervous System tumors identifies activity of the CDK4/6 inhibitor abemaciclib in recurrent meningioma.
    Neuro Oncol. 2025 Aug 16:noaf184. doi: 10.1093.
    PubMed         Abstract available
    
    
40. JACOBSEN J, Locallo A, O'Rourke CJ, Carlsen JF, et al
    Clinical, Radiological, and Molecular Insights into Extracranial Metastases from Adult Gliomas.
    Neuro Oncol. 2025 Aug 16:noaf178. doi: 10.1093.
    PubMed         Abstract available
    
    
41. MAEDA S, Kitano Y, Ohka F, Motomura K, et al
    Rapid Intraoperative Genetic Analysis of Adult-type Diffuse Gliomas Using a Microfluidic Real-Time Polymerase Chain Reaction Device.
    Neuro Oncol. 2025 Aug 24:noaf188. doi: 10.1093.
    PubMed         Abstract available
    
    
42. MAIR MJ, Werner JM, Weller J, Barci E, et al
    Prognostic stratification of newly diagnosed IDH-mutant gliomas by [18F]fluoroethyltyrosine and [11C]methionine PET - a retrospective, bicentric cohort study.
    Neuro Oncol. 2025 Aug 23:noaf196. doi: 10.1093.
    PubMed         Abstract available
    
    
43. WEN PY, Weller M, Lee EQ, Touat M, et al
    Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions.
    Neuro Oncol. 2025 Aug 13:noaf177. doi: 10.1093.
    PubMed         Abstract available
    
    
44. BELLAMY C, Hajal C, Ligon KL, Touat M, et al
    Revisiting an old therapy for new, promising combinations: biology and perspectives of lomustine in glioma treatment.
    Neuro Oncol. 2025 Aug 13:noaf192. doi: 10.1093.
    PubMed         Abstract available
    
    

    
    Neurology

45. HERNANDEZ VITORIQUE P, Nieto Vallejo SM, Jimenez Cortes N, Delgado Gil V, et al
    Clinical Reasoning: A 29-Year-Old Woman Presenting With Seizures and an Atypical Frontal Lesion.
    Neurology. 2025;105:e214087.
    PubMed         Abstract available
    
    
46. BRUGGEMAN A, Cordier F, Deolet E, Acou M, et al
    False-Positive MOG Antibodies in a Patient With a Slow-Progressive Intramedullary Glioma.
    Neurology. 2025;105:e213864.
    PubMed        
    
    

    
    Neuroradiology

47. DASH S, Vyas S, Bhardwaj N, Ahuja CK, et al
    Synthetic MRI derived relaxometry parameters: a new insight into characterization of ring enhancing lesions of brain.
    Neuroradiology. 2024 Dec 27. doi: 10.1007/s00234-024-03533.
    PubMed         Abstract available
    
    
48. CETINOGLU YK, Sinci KA, Horoz M, Gelal F, et al
    Qualitative MRI features in the differentiation between primary and secondary CNS lymphoma.
    Neuroradiology. 2025 Mar 17. doi: 10.1007/s00234-025-03594.
    PubMed         Abstract available
    
    
49. HELLSTROM J, Huq I, Witt Nystrom P, Blomquist E, et al
    Intravoxel incoherent motion imaging and dynamic susceptibility contrast perfusion MRI in differentiation between recurrent intracranial tumor and treatment-induced changes.
    Neuroradiology. 2025 Mar 21. doi: 10.1007/s00234-025-03575.
    PubMed         Abstract available
    
    
50. ZHAO X, Fu X, Wang X, Wang S, et al
    Radiomics based on preoperative magnetic resonance imaging predict the cell lineages of nonfunctioning pituitary neuroendocrine tumors.
    Neuroradiology. 2025 Mar 21. doi: 10.1007/s00234-025-03593.
    PubMed         Abstract available
    
    
51. HAN Q, Wang D, Geng D
    Structural plasticity of the contralesional subfields of hippocampus and amygdala in patients with IDH-mutant astrocytoma and oligodendroglioma.
    Neuroradiology. 2025;67:1435-1443.
    PubMed         Abstract available
    
    
52. SAADH MJ, Albadr RJ, Sur D, Yadav A, et al
    Reproducible meningioma grading across multi-center MRI protocols via hybrid radiomic and deep learning features.
    Neuroradiology. 2025 Aug 18. doi: 10.1007/s00234-025-03725.
    PubMed         Abstract available
    
    

    
    Neurosurgery

53. TURIN CG, Kerr JM, Post KD, Zada G, et al
    Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Role of Medical Perioperative Management for Patients With Functioning Pituitary Adenomas.
    Neurosurgery. 2025;97.
    PubMed         Abstract available
    
    
54. LILLEHEI KO, Travers S, Barkhoudarian G, Oyesiku NM, et al
    Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Role of Surgery for Patients With Functioning Pituitary Adenomas.
    Neurosurgery. 2025;97.
    PubMed         Abstract available
    
    
55. JUNN JC, Post KD, Aghi MK, Zada G, et al
    Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Role of Imaging for Patients With Functioning Pituitary Adenomas.
    Neurosurgery. 2025;97.
    PubMed         Abstract available
    
    
56. WEI CZ, Niranjan A, Deng H, Puccio D, et al
    The 35-Year Evolution of Stereotactic Radiosurgery for Meningiomas.
    Neurosurgery. 2025 Aug 22. doi: 10.1227/neu.0000000000003702.
    PubMed         Abstract available
    
    

    
    Oncogene

57. LEE H, Kim D, Kim B, Shin E, et al
    Membrane flexibility induced by BST2 contributes to radioresistance in glioblastoma.
    Oncogene. 2025 Aug 18. doi: 10.1038/s41388-025-03544.
    PubMed         Abstract available
    
    

    
    Proc Natl Acad Sci U S A

58. KEAHI DL, Sanders MA, Paul MR, Webster ALH, et al
    G-quadruplexes as a source of vulnerability in BRCA2-deficient granule cell progenitors and medulloblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2503872122.
    PubMed         Abstract available
    
    
59. KHAN F, Liu Y, Whitfield D, Pang L, et al
    Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420793122.
    PubMed         Abstract available
    
    

Thank you for your interest in scientific medicine.

AMEDEO Neoplasms of the CNS is free of charge.