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  Neoplasms of the CNS

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23.03.2026

1 AJNR Am J Neuroradiol
1 Am J Clin Oncol
3 BMC Cancer
2 Cancer Res
6 Childs Nerv Syst
1 Clin Cancer Res
1 Int J Cancer
5 Int J Radiat Oncol Biol Phys
6 J Neurooncol
2 J Neurosurg
1 J Nucl Med
6 Neuro Oncol
1 Neurol Res
1 Neurology
2 Neuroradiology
2 Neurosurgery
1 Pediatr Neurosurg
2 PLoS One
3 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    AJNR Am J Neuroradiol

  1. TALEKAR K, Naghizadehkashani S, Mohamed F, Jain N, et al
    Impact of Preoperative fMRI and DTI on Neurosurgical Planning for Brain Tumors: A Multi-Institutional Survey Study.
    AJNR Am J Neuroradiol. 2026 Mar 18:ajnr.A9300. doi: 10.3174/ajnr.A9300.
    PubMed         Abstract available


    Am J Clin Oncol

  2. BROWN MH, Cherng HR, Assif JW, Sun K, et al
    Conditional Survival Estimates for Malignant Glioma Patients: Secondary Analysis of RTOG 9006.
    Am J Clin Oncol. 2026 Mar 19. doi: 10.1097/COC.0000000000001296.
    PubMed         Abstract available


    BMC Cancer

  3. BALCI TOPUZ B, Ozturk Iyilikci M
    CALLY index provides improved prognostic stratification compared with other inflammation-based scores in glioblastoma treated with the stupp protocol.
    BMC Cancer. 2026 Mar 20. doi: 10.1186/s12885-026-15852.
    PubMed        

  4. LI J, Tai Y, Pan B, Xiang L, et al
    Efficacy and prognostic factors of stereotactic radiosurgery versus whole-brain radiotherapy for brain metastases in small cell lung cancer: a systematic review and meta-analysis.
    BMC Cancer. 2026 Mar 18. doi: 10.1186/s12885-026-15871.
    PubMed        

  5. HUANG J, Wang Q, Chen Y, Lin C, et al
    Regulatory mechanisms and functional analysis of cellular senescence-associated genes GAPDH, CCND1, and HBEGF in the immune microenvironment of meningioma.
    BMC Cancer. 2026 Mar 17. doi: 10.1186/s12885-026-15593.
    PubMed        


    Cancer Res

  6. VALLEBUONA EJ, Smalley I
    Spatially Resolved Opto-Omics Uncovers Functional Microglial Subtypes in Brain Metastasis.
    Cancer Res. 2026;86:1345-1346.
    PubMed         Abstract available

  7. TSUJI T, Hirose H, Sugiyama D, Shindo M, et al
    Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells.
    Cancer Res. 2026;86:1414-1434.
    PubMed         Abstract available


    Childs Nerv Syst

  8. CAVALHEIRO S, Quiroz JAR, Dastoli PA, Kim IHT, et al
    Pilocytic astrocytoma surgery via the pineal region in a 9-year-old boy via the infratentorial-supracerebellar approach.
    Childs Nerv Syst. 2026;42:124.
    PubMed         Abstract available

  9. AHMED S, Abdullah M, Batool S, Fatima H, et al
    Diagnostic challenges and treatment barriers in the management of diffuse intrinsic pontine glioma in low- and lower-middle-income countries: a systematic review.
    Childs Nerv Syst. 2026;42:112.
    PubMed         Abstract available

  10. LIN W, Qiu Y, Ma Z, Yuan H, et al
    Mammosomatotroph pituitary neuroendocrine tumour in a 7-year-old boy: case report.
    Childs Nerv Syst. 2026;42:123.
    PubMed         Abstract available

  11. LIU K, Wang X, Zhang S, Feng S, et al
    Diagnosis, treatment, and postoperative follow-up of intracranial Ewing sarcoma (EWS): a case report.
    Childs Nerv Syst. 2026;42:118.
    PubMed         Abstract available

  12. VITULLI F, Berardinelli J, Bove I, Lorenzetti M, et al
    Surgical management of pediatric pineal region tumors: an overview of current strategies.
    Childs Nerv Syst. 2026;42:117.
    PubMed         Abstract available

  13. MASUMOTO A, Hirotsu T, Nonaka Y, Murayama Y, et al
    Large terminal syringomyelia associated with terminal lipoma: mid- to long-term outcomes after tethered cord release.
    Childs Nerv Syst. 2026;42:111.
    PubMed         Abstract available


    Clin Cancer Res

  14. SANVITO F, Raymond C, Telesca D, Yao J, et al
    Framework for statistical parametric mapping of the interactions between glioblastoma location, treatment, prognostic variables, and survival using a phase III trial.
    Clin Cancer Res. 2026 Mar 16. doi: 10.1158/1078-0432.CCR-25-4419.
    PubMed         Abstract available


    Int J Cancer

  15. GUTZMER R, Weichenthal M, Eigentler T, Mohr P, et al
    Real-world effectiveness and safety with nivolumab plus ipilimumab or nivolumab alone in patients with or without melanoma brain metastasis: Results from the German noninterventional NICO study.
    Int J Cancer. 2026 Mar 15. doi: 10.1002/ijc.70440.
    PubMed         Abstract available


    Int J Radiat Oncol Biol Phys

  16. JABLONSKA PA, Serrano D, Galan N, Barranco J, et al
    A New Predictive Model for Radiation Necrosis Risk based on PTV-enriched Blood Inflammatory Biomarkers in Patients with Brain Metastases Treated with Stereotactic Radiosurgery.
    Int J Radiat Oncol Biol Phys. 2026 Mar 12:S0360-3016(26)00488.
    PubMed         Abstract available

  17. AZNAR MC, Davey A, Wilson LJ, Osorio EV, et al
    Cognitive outcomes after radiotherapy for medulloblastoma: a voxel-based analysis.
    Int J Radiat Oncol Biol Phys. 2026 Mar 12:S0360-3016(26)00492.
    PubMed         Abstract available

  18. SLEVIN F, Chen XS, Rosen BS, Shen CJ, et al
    Constraints, cumulative doses and toxicity outcomes in glioma reirradiation: a systematic review and radiobiological comparison from the Reirradiation Collaborative Group (ReCog).
    Int J Radiat Oncol Biol Phys. 2026 Mar 12:S0360-3016(26)00486.
    PubMed         Abstract available

  19. GUI C, Jenabi M, Daly J, Gillick C, et al
    Functional Magnetic Resonance Imaging-Guided Stereotactic Radiosurgery to Avoid Symptomatic Radionecrosis.
    Int J Radiat Oncol Biol Phys. 2026;124:1186-1198.
    PubMed         Abstract available

  20. AKHAVAN-SIGARI A, Sbaih O, Hori YS, Mathieu D, et al
    Perilesional Edema as a Predictor of Local Failure in Metastatic Brain Lesions Treated With Stereotactic Radiosurgery: A Systematic Review and Meta-Analysis.
    Int J Radiat Oncol Biol Phys. 2026;124:1199-1207.
    PubMed         Abstract available


    J Neurooncol

  21. NADEL JL, Gamboa NT, Botros D, Crabb BT, et al
    Lower-grade glioma imaging volumes and survival: a single-institution analysis of 90 patients after resection using intraoperative MRI.
    J Neurooncol. 2026;177:63.
    PubMed         Abstract available

  22. LU Y, Cao J, Liu X, Wang H, et al
    The predictive value of serum neurofilament light chain combined with inflammatory biomarkers for post-surgical epilepsy after brain tumor resection: a retrospective diagnostic study.
    J Neurooncol. 2026;177:61.
    PubMed        

  23. CHEHADE R, Al-Humiqani A, Hanna L, Sahgal A, et al
    Brain metastases among patients with gynecologic cancers: a single-centre retrospective study of patients treated with brain radiotherapy.
    J Neurooncol. 2026;177:58.
    PubMed        

  24. SARKAR MM, Gonsalves N, Davarzani A, Mitchell E, et al
    Disrupting Akt-Wnt/beta-catenin signaling suppresses glioblastoma stem cell growth and tumor progression in immunocompetent mice.
    J Neurooncol. 2026;177:56.
    PubMed         Abstract available

  25. BINDAL S, Gonzalez B, Dono A, Riascos R, et al
    Patterns of failure following stereotactic radiosurgery salvage for recurrent high-grade glioma.
    J Neurooncol. 2026;177:55.
    PubMed         Abstract available

  26. ELIA A, Roux A, Demasi M, Debacker C, et al
    Neurocognitive functioning, seizure control, and return to work after awake surgery with or without adjuvant therapy in IDH-mutant grade 3 diffuse gliomas.
    J Neurooncol. 2026;177:53.
    PubMed        


    J Neurosurg

  27. HONEYMAN SI, Akhbari M, Voets NL, Stacey R, et al
    Speech mapping in awake high-grade glioma resection: subcortical tract proximity as a predictor of language outcomes.
    J Neurosurg. 2026 Mar 13:1-11. doi: 10.3171/2025.10.JNS251541.
    PubMed         Abstract available

  28. DUNAS T, Jensdottir M, Solheim O, Corell A, et al
    Epidemiology of ischemic lesions after diffuse low-grade glioma resection: a Scandinavian multicenter study.
    J Neurosurg. 2026 Mar 13:1-11. doi: 10.3171/2025.10.JNS25658.
    PubMed         Abstract available


    J Nucl Med

  29. LI EJ, Kraya A, Costa-Pinheiro P, Scheuermann J, et al
    Metabolic Imaging and Molecular Signatures Reveal Metabolic Phenotypes in Recurrent Glioblastoma.
    J Nucl Med. 2026 Mar 19:jnumed.125.271476. doi: 10.2967/jnumed.125.271476.
    PubMed         Abstract available


    Neuro Oncol

  30. PUROW B
    A dangerous chip off the old block promoting brain metastasis in inflammatory breast cancer.
    Neuro Oncol. 2026 Mar 13:noag049. doi: 10.1093.
    PubMed        

  31. FU M, Feng Y, Sun P, You M, et al
    DNA Methylation Profiling Reveals a Novel Subtype Harboring IDH Mutation in H3-altered Gliomas.
    Neuro Oncol. 2026 Mar 14:noag054. doi: 10.1093.
    PubMed         Abstract available

  32. LIN J, Liang L, Zhu X, Liu J, et al
    RGS2 Promotes Brain Metastasis of Cisplatin-resistant Non-small Cell Lung Cancer through Caspase-1/IL-1beta Signaling Pathway.
    Neuro Oncol. 2026 Mar 14:noag055. doi: 10.1093.
    PubMed         Abstract available

  33. JANGDE N, Lee MH, Ruiz L, Egan I, et al
    RAC1 Regulates SHH-Medulloblastoma Growth via GLI-Mediated Transcription.
    Neuro Oncol. 2026 Mar 19:noag057. doi: 10.1093.
    PubMed         Abstract available

  34. TONG T, Hendriksen JD, Elbaek KJ, Molnar K, et al
    Combined Patch-clamp Electrophysiology and Single-Cell Genomic Analysis Reveal Spiking Tumor Cells at the Neocortical Glioblastoma Interface in Humans.
    Neuro Oncol. 2026 Mar 19:noag059. doi: 10.1093.
    PubMed         Abstract available

  35. PANG YC, Wang C, Qiu JF, Chen HX, et al
    Targeting tumor-associated macrophages-induced IGF1/PI3K/Zic1 axis triggers SHH medulloblastoma regression and chemosensitization.
    Neuro Oncol. 2026 Mar 19:noag058. doi: 10.1093.
    PubMed         Abstract available


    Neurol Res

  36. DING C, Xu Y, Guo Q, Qian Z, et al
    Peroxidasin promotes malignant progression by enhancing glycolytic metabolism in glioblastoma through the regulation of LDHA.
    Neurol Res. 2026 Mar 17:1-15. doi: 10.1080/01616412.2026.2647415.
    PubMed         Abstract available


    Neurology

  37. MULLER KJ, Karschnia P, Kaulen LD, Reis J, et al
    Clinical Manifestations of Primary CNS T-Cell Lymphoma: A Retrospective Study of Histopathologic, Molecular, and Neuroimaging Features.
    Neurology. 2026;106:e214744.
    PubMed         Abstract available


    Neuroradiology

  38. STANSKI M, Goralewski M, Watorek J, Antczak S, et al
    Contra-lesional hippocampus in low grade glioma patients with no hippocampal infiltration - a study of structural remodelling.
    Neuroradiology. 2026 Mar 16. doi: 10.1007/s00234-026-03958.
    PubMed        

  39. ZUO X, Ruan Y, Che Z, Yang J, et al
    Vascular permeability mediates contralateral glymphatic dysfunction across glioma grades and IDH status.
    Neuroradiology. 2026 Mar 19. doi: 10.1007/s00234-026-03963.
    PubMed        


    Neurosurgery

  40. MALDONADO J, Patel B, Ma T, Zohdy YM, et al
    Comprehensive Comparison of Visual Outcomes in Macro and Giant Prolactinoma Cohorts Managed With Medical Versus Surgical Treatment.
    Neurosurgery. 2025 Aug 6. doi: 10.1227/neu.0000000000003667.
    PubMed         Abstract available

  41. DAYYANI M, Filippov A, Zhang I, Georges J, et al
    RAGE Inhibition Reduces Surgery-Induced Cerebral Edema After Glioma Resection.
    Neurosurgery. 2026 Mar 19. doi: 10.1227/neu.0000000000003987.
    PubMed         Abstract available


    Pediatr Neurosurg

  42. SHIMONY N, Weatherspoon S, Hanzlik E, Khan RB, et al
    State of the art management of children with intractable epilepsy and brain tumors.
    Pediatr Neurosurg. 2026 Mar 17:1-32. doi: 10.1159/000551567.
    PubMed         Abstract available


    PLoS One

  43. LIU B, Peng D, Chen Y, Li Q, et al
    Multi-omics analysis identifies CCNB1 as a cell cycle factor driving glioblastoma progression and its inhibition by resveratrol.
    PLoS One. 2026;21:e0344872.
    PubMed         Abstract available

  44. NAKAO S, Uemichi Y, Nagano S, Mabuchi M, et al
    Effect of anticancer activity of aripiprazole main metabolite OPC-14857 on malignant glioblastoma.
    PLoS One. 2026;21:e0338895.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  45. CHEN X, Zhong X, Yue W, Wang B, et al
    A transcription regulator atlas identifies TOX3 as an Atoh1 coactivator in cerebellar development and tumorigenesis.
    Proc Natl Acad Sci U S A. 2026;123:e2527163123.
    PubMed         Abstract available

  46. BILLINGHAM LK, DeLay SL, Eshac Y, Chia TY, et al
    Microglial fructose metabolism is essential for glioblastoma growth.
    Proc Natl Acad Sci U S A. 2026;123:e2521256123.
    PubMed         Abstract available

  47. FU Z, Zhao X, Zhang Q, Han M, et al
    Synthetic SIGLEC9-based chimeric switch receptor augments the efficacy of CAR macrophages against glioblastoma.
    Proc Natl Acad Sci U S A. 2026;123:e2519819123.
    PubMed         Abstract available


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