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Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Neoplasms of the CNS

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24.03.2025

1 Br J Cancer
3 Childs Nerv Syst
1 Clin Cancer Res
1 Clin Neuropathol
6 Int J Radiat Oncol Biol Phys
3 J Neurooncol
2 J Neurosurg
2 Neuro Oncol
1 Neuroradiology
1 Neurosurgery
1 Pediatr Hematol Oncol
1 Pediatr Neurol
1 PLoS One
1 Proc Natl Acad Sci U S A
1 Rev Neurol (Paris)


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Br J Cancer

  1. STRASSHEIMER F, Elleringmann P, Ludmirski G, Roller B, et al
    CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma.
    Br J Cancer. 2025 Mar 18. doi: 10.1038/s41416-025-02977.
    PubMed         Abstract available


    Childs Nerv Syst

  2. JUNG G, Cohen JM, Oriko D, Buckner-Wolfson E, et al
    Endoscopic endonasal versus open approach for craniopharyngioma treatment: a systematic review of clinical characteristics.
    Childs Nerv Syst. 2025;41:131.
    PubMed         Abstract available

  3. SHARIFI G, Paraandavaji E, Nasab MMM, Mohammadi E, et al
    Clinical and surgical outcomes of pediatric Cushing's disease following endoscopic transsphenoidal surgery.
    Childs Nerv Syst. 2025;41:130.
    PubMed         Abstract available

  4. HORIKOSHI K, Iimura Y, Suzuki H, Suzuki M, et al
    Spontaneous regression of epileptogenic pilocytic astrocytoma with FGFR1-TACC1 fusion.
    Childs Nerv Syst. 2025;41:129.
    PubMed         Abstract available


    Clin Cancer Res

  5. ZHOU W, Yue Q, Yuan Y, Huang Q, et al
    Visualization of P2X7 Receptors in Living Human Gliomas: an 18F-GSK1482160 PET Imaging and Neuropatholopy Study.
    Clin Cancer Res. 2025 Mar 17. doi: 10.1158/1078-0432.CCR-24-2830.
    PubMed         Abstract available


    Clin Neuropathol

  6. GANT T, Bannykh S
    Highly infiltrative brain metastasis of RET mutant lung primary: Morphometric assessment and molecular review.
    Clin Neuropathol. 2025 Mar 21. doi: 10.5414/NP301658.
    PubMed         Abstract available


    Int J Radiat Oncol Biol Phys

  7. LIU Z, Mitchell TJ, Luo C, Park KY, et al
    Neurocognitive and resting-state functional MRI changes in patients with diffuse gliomas after chemoradiotherapy.
    Int J Radiat Oncol Biol Phys. 2025 Mar 17:S0360-3016(25)00247.
    PubMed         Abstract available

  8. KARP JM, Kruser TJ
    Contouring with FLAIR: Targeting Peritumoral Edema (and Beyond) in Glioblastoma.
    Int J Radiat Oncol Biol Phys. 2025;121:1182-1184.
    PubMed        

  9. KLEBANER D, Pollom EL, Rahimy E, Gibbs IC, et al
    Phase I/II Dose-Escalation Trial of 3-Fraction Stereotactic Radiosurgery for Resection Cavities from Large Brain Metastases.
    Int J Radiat Oncol Biol Phys. 2025 Mar 13:S0360-3016(25)00242.
    PubMed         Abstract available

  10. TRINGALE KR, Grommes C, Ucpinar BA, Reiner AS, et al
    Consolidation Regimen and Cerebral Atrophy in Patients with Primary Central Nervous System Lymphoma.
    Int J Radiat Oncol Biol Phys. 2024 Nov 28:S0360-3016(24)03661.
    PubMed         Abstract available

  11. WANG JH, Oglesby R, Tran A, Guryildirim M, et al
    The Association of Linear Energy Transfer and Dose With Radiation Necrosis After Pencil Beam Scanning Proton Therapy in Pediatric Posterior Fossa Tumors.
    Int J Radiat Oncol Biol Phys. 2025;121:1219-1228.
    PubMed         Abstract available

  12. GILL GS, Baliga S, Lewy J, Bajaj BV, et al
    Exploring the Relationship Between Radiation-Induced Moyamoya Syndrome and Radiation Dose for Pediatric Patients Treated With Proton Radiation Therapy.
    Int J Radiat Oncol Biol Phys. 2025;121:1209-1218.
    PubMed         Abstract available


    J Neurooncol

  13. MAZA EJL, Pavoni JF, Leoni RF
    Early and late structural brain changes after radiation therapy: an MRI study in glioma patients.
    J Neurooncol. 2025 Mar 21. doi: 10.1007/s11060-025-05008.
    PubMed         Abstract available

  14. NEIMANTAITE A, Carstam L, Gomez Vecchio T, Haggstrom I, et al
    Survival prediction with radiomics for patients with IDH mutated lower-grade glioma.
    J Neurooncol. 2025 Mar 18. doi: 10.1007/s11060-025-05006.
    PubMed         Abstract available

  15. MULLER HL
    Long-term quality of life and hypothalamic dysfunction after craniopharyngioma.
    J Neurooncol. 2025 Mar 17. doi: 10.1007/s11060-025-04987.
    PubMed         Abstract available


    J Neurosurg

  16. CHO A, Gatterbauer B, Chen Y, Jankowski T, et al
    Effect of cumulative dexamethasone dose on the outcome of patients with radiosurgically treated brain metastases in the era of modern oncological therapy.
    J Neurosurg. 2025 Mar 14:1-12. doi: 10.3171/2024.12.JNS241771.
    PubMed         Abstract available

  17. TANG L, Chakravarti S, Venkatdas R, Derin E, et al
    Association of shorter time to surgery with improved overall survival for atypical intracranial meningiomas: an analysis using the National Cancer Database.
    J Neurosurg. 2025 Mar 21:1-9. doi: 10.3171/2024.11.JNS241896.
    PubMed         Abstract available


    Neuro Oncol

  18. FOLTYN-DUMITRU M, Banan R, Schell M, Mahmutoglu MA, et al
    Histopathological and molecular characteristics of IDH-wildtype glioblastoma without contrast enhancement: implications for clinical outcomes.
    Neuro Oncol. 2025 Mar 20:noaf070. doi: 10.1093.
    PubMed         Abstract available

  19. XUE Z, Zhang X, Mao B, Mu G, et al
    Dual role of WNT10A in promoting the malignancy of glioblastoma and remodeling the tumor microenvironment.
    Neuro Oncol. 2025 Mar 18:noaf075. doi: 10.1093.
    PubMed         Abstract available


    Neuroradiology

  20. RAMAGLIA A, Parodi C, Milanaccio C, Verrico A, et al
    Use of amide proton transfer (APT) imaging in the differentiation of pediatric low-grade brain tumors from tumor-like brain lesions.
    Neuroradiology. 2025 Mar 21. doi: 10.1007/s00234-025-03582.
    PubMed         Abstract available


    Neurosurgery

  21. HUNTOON K, Elder JB, Finger G, Ormond DR, et al
    Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines Update for the Role of Emerging Therapies in the Management of Patients With Metastatic Brain Tumors.
    Neurosurgery. 2025 Mar 17. doi: 10.1227/neu.0000000000003383.
    PubMed         Abstract available


    Pediatr Hematol Oncol

  22. CHENG S, Riedlinger S, Ronsley R, Stewart L, et al
    Primary gonadal failure in children with intracranial brain tumors treated with high dose alkylating agents and radiation sparing therapy: an institutional case series.
    Pediatr Hematol Oncol. 2025 Mar 20:1-8. doi: 10.1080/08880018.2025.2480741.
    PubMed         Abstract available


    Pediatr Neurol

  23. OKAMOTO M, Yamaguchi S, Sawaya R, Ishi Y, et al
    Long-Term Outcome and Social-Intellectual Ability of Patients With Basal Ganglia Germinoma.
    Pediatr Neurol. 2025;165:16-21.
    PubMed         Abstract available


    PLoS One

  24. MANU DR, Balasa R, Pruteanu LL, Curean V, et al
    Identification of distinct profiles of glioblastoma through the immunocapture of extracellular vesicles from patient plasma.
    PLoS One. 2025;20:e0315890.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A


  25. Correction for Xu et al., BCL6 promotes glioma and serves as a therapeutic target.
    Proc Natl Acad Sci U S A. 2025;122:e2504152122.
    PubMed        


    Rev Neurol (Paris)

  26. VALYRAKI N, Ahle G, Tabouret E, Houot R, et al
    Primary central nervous system lymphoma of the spinal cord: A LOC network cohort study.
    Rev Neurol (Paris). 2025;181:200-209.
    PubMed         Abstract available


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