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  Neoplasms of the CNS

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Articles published in Int J Cancer

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Single Articles

    September 2020
  1. ZHANG Y, Xie A, Quan F, Hou X, et al
    Identifying bifurcated paths with differential function impact in glioblastomas evolution.
    Int J Cancer. 2020 Sep 1. doi: 10.1002/ijc.33276.
    PubMed     Abstract available

    June 2020
  2. KANDELS D, Pietsch T, Bison B, Warmuth-Metz M, et al
    Loss of efficacy of subsequent non-surgical therapy after primary treatment failure in pediatric low-grade glioma patients - report from the German SIOP-LGG 2004 cohort.
    Int J Cancer. 2020 Jun 24. doi: 10.1002/ijc.33170.
    PubMed     Abstract available

    April 2020
  3. ULASOV IV, Mijanovic O, Savchuk S, Gonzalez-Buendia E, et al
    TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway.
    Int J Cancer. 2020;146:2218-2228.
    PubMed     Abstract available

  4. FALKENSTEIN F, Gessi M, Kandels D, Ng HK, et al
    Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO-grade II - report from the German/Swiss SIOP-LGG 2004 cohort.
    Int J Cancer. 2020 Apr 2. doi: 10.1002/ijc.32995.

    March 2020
  5. FU F, Zhang Y, Gao Z, Zhao Y, et al
    Development and Validation of a Five-Gene Model to Predict Postoperative Brain Metastasis in Operable Lung Adenocarcinoma.
    Int J Cancer. 2020 Mar 17. doi: 10.1002/ijc.32981.
    PubMed     Abstract available

    February 2020
  6. FARES J, Kanojia D, Rashidi A, Ulasov I, et al
    Landscape of Combination Therapy Trials in Breast Cancer Brain Metastasis.
    Int J Cancer. 2020 Feb 22. doi: 10.1002/ijc.32937.
    PubMed     Abstract available

  7. PATEL DM, Jones RR, Booth BJ, Olsson AC, et al
    Parental occupational exposure to pesticides, animals and organic dust and risk of childhood leukemia and central nervous system tumors: Findings from the International Childhood Cancer Cohort Consortium (I4C).
    Int J Cancer. 2020;146:943-952.
    PubMed     Abstract available

  8. SIKPA D, Whittingstall L, Fouquet JP, Radulska A, et al
    Cerebrovascular inflammation promotes the formation of brain metastases.
    Int J Cancer. 2020 Feb 3. doi: 10.1002/ijc.32902.
    PubMed     Abstract available

    December 2019
  9. PELTONEN S, Kallionpaa RA, Rantanen M, Uusitalo E, et al
    Pediatric malignancies in neurofibromatosis type 1: A population-based cohort study.
    Int J Cancer. 2019;145:2926-2932.
    PubMed     Abstract available

    October 2019
  10. HOLZAPFEL J, Kandels D, Schmidt R, Pietsch T, et al
    Favorable prognosis in pediatric brainstem low-grade glioma - report from the German SIOP-LGG 2004 cohort.
    Int J Cancer. 2019 Oct 15. doi: 10.1002/ijc.32734.

  11. VAN OPIJNEN MP, Dirven L, Coremans IEM, Taphoorn MJB, et al
    The impact of current treatment modalities on the outcomes of patients with melanoma brain metastases: a systematic review.
    Int J Cancer. 2019 Oct 3. doi: 10.1002/ijc.32696.
    PubMed     Abstract available

    August 2019
  12. MALLM JP, Windisch P, Biran A, Gal Z, et al
    Glioblastoma initiating cells are sensitive to histone demethylase inhibition due to epigenetic deregulation.
    Int J Cancer. 2019 Aug 28. doi: 10.1002/ijc.32649.
    PubMed     Abstract available

  13. MATHIOS D, Hwang T, Xia Y, Phallen J, et al
    Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types.
    Int J Cancer. 2019 Aug 2. doi: 10.1002/ijc.32587.
    PubMed     Abstract available

    July 2019
  14. COTE DJ, Bever AM, Wilson KM, Smith TR, et al
    A Prospective Study of Tea and Coffee Intake and Risk of Glioma.
    Int J Cancer. 2019 Jul 15. doi: 10.1002/ijc.32574.
    PubMed     Abstract available

    June 2019
  15. KIM SS, Harford JB, Moghe M, Slaughter T, et al
    A tumor-targeting nanomedicine carrying the p53 gene crosses the blood-brain barrier and enhances anti-PD-1 immunotherapy in mouse models of glioblastoma.
    Int J Cancer. 2019 Jun 26. doi: 10.1002/ijc.32531.
    PubMed     Abstract available

  16. FLEURENCE J, Bahri M, Fougeray S, Faraj S, et al
    Impairing Temozolomide Resistance Driven by Glioma Stem-like Cells with adjuvant Immunotherapy Targeting O-acetyl GD2 Ganglioside.
    Int J Cancer. 2019 Jun 26. doi: 10.1002/ijc.32533.
    PubMed     Abstract available

  17. CARELLA A, Tejedor JR, Garcia MG, Urdinguio RG, et al
    Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis.
    Int J Cancer. 2019 Jun 18. doi: 10.1002/ijc.32520.
    PubMed     Abstract available

    May 2019
  18. YE J, Zhu J, Chen H, Qian J, et al
    A novel lncRNA-LINC01116 regulates Tumorigenesis of Glioma by targeting VEGFA.
    Int J Cancer. 2019 May 29. doi: 10.1002/ijc.32483.
    PubMed     Abstract available

  19. VARON M, Levy T, Mazor G, Ben David H, et al
    The long non-coding RNA TP73-AS1 promotes tumorigenicity of medulloblastoma cells.
    Int J Cancer. 2019 May 13. doi: 10.1002/ijc.32400.
    PubMed     Abstract available

  20. ZHOU S, Zhao X, Yang Z, Yang R, et al
    Neddylation Inhibition Upregulates PD-L1 Expression and Enhances the Efficacy of Immune Checkpoint Blockade in Glioblastoma.
    Int J Cancer. 2019 May 1. doi: 10.1002/ijc.32379.
    PubMed     Abstract available

    April 2019
  21. BARASH U, Spyrou A, Liu P, Vlodavsky E, et al
    Heparanase promotes glioma progression via enhancing CD24 expression.
    Int J Cancer. 2019 Apr 29. doi: 10.1002/ijc.32375.

  22. VINCHURE OS, Sharma V, Tabasum S, Ghosh S, et al
    Polycomb complex mediated epigenetic reprogramming alters TGF-beta signaling via a novel EZH2/miR-490/TGIF2 axis thereby inducing migration and EMT potential in glioblastomas.
    Int J Cancer. 2019 Apr 22. doi: 10.1002/ijc.32360.
    PubMed     Abstract available

  23. SELIGER C, Genbrugge E, Gorlia T, Chinot O, et al
    Use of metformin and outcome of patients with newly diagnosed glioblastoma - pooled analysis.
    Int J Cancer. 2019 Apr 13. doi: 10.1002/ijc.32337.
    PubMed     Abstract available

  24. OSTROM QT, Egan KM, Nabors LB, Gerke T, et al
    Glioma risk associated with extent of estimated European genetic ancestry in African-Americans and Hispanics.
    Int J Cancer. 2019 Apr 9. doi: 10.1002/ijc.32318.
    PubMed     Abstract available

  25. WANG Y, Xia Y, Hu K, Zeng M, et al
    MKK7 transcription positively or negatively regulated by SP1 and KLF5 depends on HDAC4 activity in glioma.
    Int J Cancer. 2019 Apr 9. doi: 10.1002/ijc.32321.
    PubMed     Abstract available

    March 2019
  26. DE VEGA S, Kondo A, Suzuki M, Arai H, et al
    Fibulin-7 is over-expressed in glioblastomas and modulates glioblastoma neovascularization through interaction with angiopoietin-1.
    Int J Cancer. 2019 Mar 28. doi: 10.1002/ijc.32306.
    PubMed     Abstract available

  27. MUELLER S, Jain P, Liang WS, Kilburn L, et al
    A pilot precision medicine trial for children with diffuse intrinsic pontine glioma - PNOC003: a report from the Pacific Pediatric Neuro-Oncology Consortium.
    Int J Cancer. 2019 Mar 12. doi: 10.1002/ijc.32258.
    PubMed     Abstract available

    February 2019
  28. CHEN H, Chen G, Li G, Zhang S, et al
    Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility.
    Int J Cancer. 2019 Feb 4. doi: 10.1002/ijc.32179.
    PubMed     Abstract available

    January 2019
  29. ZHANG X, Lu X, Liu Z, Guan R, et al
    Integrating multiple-level molecular data to infer the distinctions between glioblastoma and lower-grade glioma.
    Int J Cancer. 2019 Jan 29. doi: 10.1002/ijc.32174.
    PubMed     Abstract available

  30. CHEN Q, Han B, Meng X, Duan C, et al
    Immunogenomic analysis reveals LGALS1 contributes to the immune heterogeneity and immunosuppression in glioma.
    Int J Cancer. 2019 Jan 7. doi: 10.1002/ijc.32102.
    PubMed     Abstract available

    December 2018
  31. LE RHUN E, von Achenbach C, Lohmann B, Silginer M, et al
    Profound, durable and MGMT-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition.
    Int J Cancer. 2018 Dec 14. doi: 10.1002/ijc.32069.
    PubMed     Abstract available

  32. GUO X, Qiu W, Wang J, Liu Q, et al
    Glioma exosomes mediate the expansion and function of myeloid-derived suppressor cells through microRNA-29a/Hbp1 and microRNA-92a/Prkar1a pathways.
    Int J Cancer. 2018 Dec 11. doi: 10.1002/ijc.32052.
    PubMed     Abstract available

  33. SA JK, Choi SW, Zhao J, Lee Y, et al
    Hypermutagenesis in untreated adult gliomas due to inherited mismatch mutations.
    Int J Cancer. 2018 Dec 11. doi: 10.1002/ijc.32054.
    PubMed     Abstract available

    November 2018
  34. ZHU S, Lv X, Zhang X, Li T, et al
    An effective dendritic cell-based vaccine containing glioma stem-like cell lysate and CpG adjuvant for an orthotopic mouse model of glioma.
    Int J Cancer. 2018 Nov 22. doi: 10.1002/ijc.32008.
    PubMed     Abstract available

  35. SELIGER C, Gerken M, Leitzmann MF, Hau P, et al
    Reply to Lu: Connecting the dots between metformin and high-grade glioma.
    Int J Cancer. 2018 Nov 13. doi: 10.1002/ijc.31990.

  36. LU VM
    Connecting the dots between metformin and high-grade glioma.
    Int J Cancer. 2018 Nov 13. doi: 10.1002/ijc.31987.

  37. CORBETTA C, Di Ianni N, Bruzzone MG, Patane M, et al
    Altered function of the glutamate-aspartate transporter GLAST, a potential therapeutic target in glioblastoma.
    Int J Cancer. 2018 Nov 12. doi: 10.1002/ijc.31985.
    PubMed     Abstract available

  38. FALCHETTI ML, D'Alessandris QG, Pacioni S, Buccarelli M, et al
    Glioblastoma endothelium drives bevacizumab-induced infiltrative growth via modulation of PLXDC1.
    Int J Cancer. 2018 Nov 10. doi: 10.1002/ijc.31983.
    PubMed     Abstract available

    October 2018
  39. JOHANNESSEN TA, Hasan-Olive MAM, Zhu H, Denisova O, et al
    Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.
    Int J Cancer. 2018 Oct 5. doi: 10.1002/ijc.31912.
    PubMed     Abstract available

    September 2018
  40. HARRIS-BOOKMAN S, Mathios D, Martin AM, Xia Y, et al
    Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma.
    Int J Cancer. 2018 Sep 24. doi: 10.1002/ijc.31661.
    PubMed     Abstract available

    August 2018
  41. OSTROM QT, Kinnersley B, Armstrong G, Rice T, et al
    Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
    Int J Cancer. 2018 Aug 27. doi: 10.1002/ijc.31759.
    PubMed     Abstract available

  42. SELIGER C, Luber C, Gerken M, Schaertl J, et al
    Use of metformin and survival of patients with high-grade glioma.
    Int J Cancer. 2018 Aug 9. doi: 10.1002/ijc.31783.
    PubMed     Abstract available

  43. JI J, Sundquist J, Sundquist K
    Increased incidence of inguinal hernia in offspring of female survivors of childhood central nervous system tumors.
    Int J Cancer. 2018;143:591-596.
    PubMed     Abstract available

    July 2018
  44. IZRAELY S, Ben-Menachem S, Sagi-Assif O, Telerman A, et al
    The Metastatic Microenvironment: Melanoma-Microglia Cross-Talk Promotes the Malignant Phenotype of Melanoma Cells.
    Int J Cancer. 2018 Jul 11. doi: 10.1002/ijc.31745.
    PubMed     Abstract available

    June 2018
  45. FERGUSON SD, Zheng S, Xiu J, Zhou S, et al
    Profiles of Brain Metastases: Prioritization of Therapeutic Targets.
    Int J Cancer. 2018 Jun 19. doi: 10.1002/ijc.31624.
    PubMed     Abstract available

    May 2018
  46. PEVERELLI E, Giardino E, Treppiedi D, Catalano R, et al
    A novel pathway activated by somatostatin receptor type 2 (SST2): Inhibition of pituitary tumor cell migration and invasion through cytoskeleton protein recruitment.
    Int J Cancer. 2018;142:1842-1852.
    PubMed     Abstract available

    April 2018
  47. RAASCHOU-NIELSEN O, Hvidtfeldt U, Roswall N, Hertel O, et al
    Ambient benzene at the residence and risk for subtypes of childhood leukaemia, lymphoma and CNS tumour.
    Int J Cancer. 2018 Apr 6. doi: 10.1002/ijc.31421.
    PubMed     Abstract available

    March 2018
  48. WIRTHSCHAFT P, Bode J, Simon AEM, Hoffmann E, et al
    A PRDX1-p38alpha heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas.
    Int J Cancer. 2018 Mar 26. doi: 10.1002/ijc.31404.
    PubMed     Abstract available

    February 2018
  49. ZHANG G, Chen L, Khan AA, Li B, et al
    miRNA-124-3p/neuropilin-1(NRP-1) axis plays an important role in mediating glioblastoma growth and angiogenesis.
    Int J Cancer. 2018 Feb 19. doi: 10.1002/ijc.31329.
    PubMed     Abstract available

  50. ERDMANN F, Winther JF, Dalton SO, Zeeb H, et al
    Survival from tumours of the central nervous system in Danish children: Is survival related to family circumstances?
    Int J Cancer. 2018;142:671-680.
    PubMed     Abstract available

  51. LI X, Wang Y, Wang J, Zhang T, et al
    Enhanced efficacy of AZD3759 and radiation on brain metastasis from EGFR mutant non-small cell lung cancer.
    Int J Cancer. 2018 Feb 12. doi: 10.1002/ijc.31303.
    PubMed     Abstract available

  52. LAI M, Vassallo I, Lanz B, Poitry-Yamate C, et al
    In vivo characterization of brain metabolism by (1) H MRS, (13) C MRS and (18) FDG PET reveals significant glucose oxidation of invasively growing glioma cells.
    Int J Cancer. 2018 Feb 8. doi: 10.1002/ijc.31299.
    PubMed     Abstract available

    January 2018
  53. CHEN Y, Zhao F, Cui D, Jiang R, et al
    HOXD-AS1/miR-130a sponge regulates glioma development by targeting E2F8.
    Int J Cancer. 2018 Jan 17. doi: 10.1002/ijc.31262.
    PubMed     Abstract available

  54. BURLEY TA, Maczynska J, Shah A, Szopa W, et al
    Near-Infrared Photoimmunotherapy Targeting EGFR - Shedding New Light on Glioblastoma Treatment.
    Int J Cancer. 2018 Jan 5. doi: 10.1002/ijc.31246.
    PubMed     Abstract available

    December 2017
  55. AGRAWAL R, Garg A, Malgulwar PB, Sharma V, et al
    P53 and miR-210 regulated NeuroD2, a neuronal basic helix-loop-helix transcription factor, is downregulated in glioblastoma patients and functions as a tumor suppressor under hypoxic microenvironment.
    Int J Cancer. 2017 Dec 11. doi: 10.1002/ijc.31209.
    PubMed     Abstract available

  56. DROOP A, Bruns A, Tanner G, Rippaus N, et al
    How to Analyse The Spatiotemporal Tumour Samples Needed To Investigate Cancer Evolution: A Case Study using Paired Primary and Recurrent Glioblastoma.
    Int J Cancer. 2017 Dec 1. doi: 10.1002/ijc.31184.
    PubMed     Abstract available

    November 2017
  57. KOMURO A, Raja E, Iwata C, Soda M, et al
    Identification of a novel fusion gene HMGA2-EGFR in glioblastoma.
    Int J Cancer. 2017 Nov 29. doi: 10.1002/ijc.31179.
    PubMed     Abstract available

  58. PIEL C, Pouchieu C, Tual S, Migault L, et al
    Central nervous system tumors and agricultural exposures in the prospective cohort AGRICAN.
    Int J Cancer. 2017;141:1771-1782.
    PubMed     Abstract available

    October 2017
  59. KOSTOPOULOU ON, Mohammad AA, Bartek J Jr, Winter J, et al
    Glucocorticoids promote a glioma stem cell-like phenotype and resistance to chemotherapy in human glioblastoma primary cells: Biological and prognostic significance.
    Int J Cancer. 2017 Oct 25. doi: 10.1002/ijc.31132.
    PubMed     Abstract available

  60. CAO M, Mao J, Duan X, Lu L, et al
    In vivo tracking of the tropism of mesenchymal stem cells to malignant gliomas using reporter gene-based MR imaging.
    Int J Cancer. 2017 Oct 19. doi: 10.1002/ijc.31113.
    PubMed     Abstract available

  61. SRIVASTAVA C, Irshad K, Dikshit B, Chattopadhyay P, et al
    FAT1 modulates EMT and stemness genes expression in hypoxic glioblastoma.
    Int J Cancer. 2017 Oct 9. doi: 10.1002/ijc.31092.
    PubMed     Abstract available

  62. CONRAD C, Gotte M, Schlomann U, Roessler M, et al
    ADAM8 expression in breast cancer derived metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells.
    Int J Cancer. 2017 Oct 7. doi: 10.1002/ijc.31090.
    PubMed     Abstract available

  63. GE H, Mu L, Jin L, Yang C, et al
    Tumor associated CD70 expression is involved in promoting tumor migration and macrophage infiltration in GBM.
    Int J Cancer. 2017;141:1434-1444.
    PubMed     Abstract available

    September 2017
  64. VIDART D'EGURBIDE BAGAZGOITIA , Bailey HD, Orsi L, Lacour B, et al
    Maternal residential pesticide use during pregnancy and risk of malignant childhood brain tumors: A pooled analysis of the ESCALE and ESTELLE studies (SFCE).
    Int J Cancer. 2017 Sep 26. doi: 10.1002/ijc.31073.
    PubMed     Abstract available

  65. CIAGLIA E, Laezza C, Abate M, Pisanti S, et al
    Recognition by Natural Killer cells of N6 -isopentenyladenosine-treated human glioma cell lines.
    Int J Cancer. 2017 Sep 7. doi: 10.1002/ijc.31036.
    PubMed     Abstract available

    August 2017
  66. ESAKI S, Nigim F, Moon E, Luk S, et al
    Blockade of transforming growth factor-beta signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models.
    Int J Cancer. 2017 Aug 12. doi: 10.1002/ijc.30929.
    PubMed     Abstract available

    July 2017
  67. YANG J, Liu R, Deng Y, Qian J, et al
    MiR-15a/16 deficiency enhances anti-tumor immunity of glioma-infiltrating CD8+ T cells through targeting mTOR.
    Int J Cancer. 2017 Jul 31. doi: 10.1002/ijc.30912.
    PubMed     Abstract available

  68. BAYSAN M, Woolard K, Cam MC, Zhang W, et al
    Detailed Longitudinal Sampling of Glioma Stem Cells In Situ Reveals Chr7 Gain and Chr10 Loss As Repeated Events in Primary Tumor Formation and Recurrence.
    Int J Cancer. 2017 Jul 14. doi: 10.1002/ijc.30887.
    PubMed     Abstract available

  69. DEJAEGHER J, Verschuere T, Vercalsteren E, Boon L, et al
    Characterization of PD-1 upregulation on tumor-infiltrating lymphocytes in human and murine gliomas and preclinical therapeutic blockade.
    Int J Cancer. 2017 Jul 6. doi: 10.1002/ijc.30877.
    PubMed     Abstract available

    May 2017
  70. JAHAN N, Lee JM, Shah K, Wakimoto H, et al
    Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus.
    Int J Cancer. 2017 May 31. doi: 10.1002/ijc.30811.
    PubMed     Abstract available

    April 2017
  71. MURRAY MJ, Bailey S, Heinemann K, Mann J, et al
    Treatment and outcomes of UK and German patients with relapsed intracranial germ cell tumors following uniform first-line therapy.
    Int J Cancer. 2017 Apr 30. doi: 10.1002/ijc.30755.
    PubMed     Abstract available

  72. PEVERELLI E, Giardino E, Treppiedi D, Meregalli M, et al
    Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors.
    Int J Cancer. 2017;140:1870-1880.
    PubMed     Abstract available

    March 2017
  73. QIAN Z, Ren L, Wu D, Yang X, et al
    Overexpression of FoxO3a is associated with glioblastoma progression and predicts poor patient prognosis.
    Int J Cancer. 2017 Mar 14. doi: 10.1002/ijc.30690.
    PubMed     Abstract available

    February 2017
  74. CIAGLIA E, Abate M, Laezza C, Pisanti S, et al
    Antiglioma effects of N6-isopentenyladenosine, an endogenous isoprenoid end product, through the downregulation of epidermal growth factor receptor.
    Int J Cancer. 2017;140:959-972.
    PubMed     Abstract available

    January 2017
  75. BAILEY HD, Rios P, Lacour B, Guerrini-Rousseau L, et al
    Factors related to pregnancy and birth and the risk of childhood brain tumours: The ESTELLE and ESCALE studies (SFCE, France).
    Int J Cancer. 2017 Jan 5. doi: 10.1002/ijc.30597.
    PubMed     Abstract available

    September 2016
  76. WANG J, Voellger B, Benzel J, Schlomann U, et al
    Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.
    Int J Cancer. 2016;139:1327-39.
    PubMed     Abstract available

    April 2016
  77. SMALLEY KS, Fedorenko IV, Kenchappa R, Sahebjam S, et al
    Managing leptomeningeal melanoma metastases in the era of immune and targeted therapy.
    Int J Cancer. 2016 Apr 15. doi: 10.1002/ijc.30147.
    PubMed     Abstract available

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