Home The Word Brain My Amedeo FAQ Privacy About   


Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts


  Neoplasms of the CNS

  Free Subscription


Articles published in J Clin Oncol

Retrieve available abstracts of 44 articles:
HTML format



Single Articles


    April 2025
  1. SPERDUTO PW, Marqueen KE, Chang E, Li J, et al
    Improved Survival and Prognostication in Melanoma Patients With Brain Metastases: An Update of the Melanoma Graded Prognostic Assessment.
    J Clin Oncol. 2025 Apr 17:JCO2401351. doi: 10.1200/JCO-24-01351.
    PubMed     Abstract available


    March 2025
  2. WEISS SA, Djureinovic D, Wei W, Tran T, et al
    Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases.
    J Clin Oncol. 2025 Mar 6:JCO2402219. doi: 10.1200/JCO-24-02219.
    PubMed     Abstract available


    January 2025
  3. KACIMI SEO, Dehais C, Feuvret L, Chinot O, et al
    Survival Outcomes Associated With First-Line Procarbazine, CCNU, and Vincristine or Temozolomide in Combination With Radiotherapy in IDH-Mutant 1p/19q-Codeleted Grade 3 Oligodendroglioma.
    J Clin Oncol. 2025;43:329-338.
    PubMed     Abstract available


  4. HUANG RY, Youssef G, Nelson T, Wen PY, et al
    Comparative Analysis of Intracranial Response Assessment Criteria in Patients With Melanoma Brain Metastases Treated With Combination Nivolumab + Ipilimumab in CheckMate 204.
    J Clin Oncol. 2025 Jan 3:JCO2400953. doi: 10.1200/JCO.24.00953.
    PubMed     Abstract available


    November 2024
  5. NOGUCHI M, Shindo Y, Wakabayashi K, Koide Y, et al
    Significance of Up-Front Stereotactic Radiosurgery for Non-Small Cell Lung Cancer Patients With Brain Metastases in the Era of New Generation Tyrosine Kinase Inhibitors.
    J Clin Oncol. 2024 Nov 15:JCO2401876. doi: 10.1200/JCO-24-01876.
    PubMed    


  6. RUSTHOVEN CG, Miao E, Boe LA, Pike LRG, et al
    Reply to: Significance of Up-Front Stereotactic Radiosurgery for Non-Small Cell Lung Cancer Patients With Brain Metastases in the Era of New Generation Tyrosine Kinase Inhibitors.
    J Clin Oncol. 2024 Nov 15:JCO2402129. doi: 10.1200/JCO-24-02129.
    PubMed    


    October 2024

  7. Erratum: Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguan
    J Clin Oncol. 2024 Oct 10:JCO2402040. doi: 10.1200/JCO-24-02040.
    PubMed    


    September 2024
  8. FORST DA, Podgurski AF, Strander SM, Whitman JD, et al
    NeuroCARE: A Randomized Controlled Trial of a Psychological Intervention for Caregivers of Patients With Primary Malignant Brain Tumors.
    J Clin Oncol. 2024 Sep 16:JCO2400065. doi: 10.1200/JCO.24.00065.
    PubMed     Abstract available


    August 2024
  9. DOWLATI A, Hummel HD, Champiat S, Olmedo ME, et al
    Sustained Clinical Benefit and Intracranial Activity of Tarlatamab in Previously Treated Small Cell Lung Cancer: DeLLphi-300 Trial Update.
    J Clin Oncol. 2024 Aug 29:JCO2400553. doi: 10.1200/JCO.24.00553.
    PubMed     Abstract available


  10. JENG MY, Yu HA
    Leptomeningeal Metastasis in the Era of CNS-Penetrant Tyrosine Kinase Inhibitor Therapy.
    J Clin Oncol. 2024;42:2727-2730.
    PubMed    


  11. LIN FY, Stuckert A, Tat C, White M, et al
    Phase I Trial of GD2.CART Cells Augmented With Constitutive Interleukin-7 Receptor for Treatment of High-Grade Pediatric CNS Tumors.
    J Clin Oncol. 2024;42:2769-2779.
    PubMed     Abstract available


    July 2024
  12. PIKE LRG, Miao E, Boe LA, Patil T, et al
    Tyrosine Kinase Inhibitors With and Without Up-Front Stereotactic Radiosurgery for Brain Metastases From EGFR and ALK Oncogene-Driven Non-Small Cell Lung Cancer (TURBO-NSCLC).
    J Clin Oncol. 2024 Jul 24:JCO2302668. doi: 10.1200/JCO.23.02668.
    PubMed     Abstract available


    June 2024
  13. YU Y, Miao E, Pike LRG
    Improved CNS Control With the Addition of Chemotherapy to Osimertinib: A Devil's Bargain?
    J Clin Oncol. 2024;42:2107-2108.
    PubMed    


  14. KOTECHA R, Schiff D, Chakravarti A, Fleming JL, et al
    Multidisciplinary Management of Isocitrate Dehydrogenase-Mutated Gliomas in a Contemporary Molecularly Defined Era.
    J Clin Oncol. 2024 Jun 4:JCO2302195. doi: 10.1200/JCO.23.02195.
    PubMed     Abstract available


  15. PEROL M, Solomon BJ, Goto K, Park K, et al
    CNS Protective Effect of Selpercatinib in First-Line RET Fusion-Positive Advanced Non-Small Cell Lung Cancer.
    J Clin Oncol. 2024 Jun 3:JCO2400724. doi: 10.1200/JCO.24.00724.
    PubMed     Abstract available


  16. PARK S, Baldry R, Jung HA, Sun JM, et al
    Phase II Efficacy and Safety of 80 mg Osimertinib in Patients With Leptomeningeal Metastases Associated With Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer (BLOSSOM).
    J Clin Oncol. 2024 Jun 3:JCO2400708. doi: 10.1200/JCO.24.00708.
    PubMed     Abstract available


  17. MIKOLAJEWICZ N, Yee PP, Bhanja D, Trifoi M, et al
    Systematic Review of Cerebrospinal Fluid Biomarker Discovery in Neuro-Oncology: A Roadmap to Standardization and Clinical Application.
    J Clin Oncol. 2024;42:1961-1974.
    PubMed     Abstract available


    March 2024
  18. XIAO H, Vaidya R, Hershman DL, Unger JM, et al
    Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022.
    J Clin Oncol. 2024 Mar 27:JCO2301777. doi: 10.1200/JCO.23.01777.
    PubMed     Abstract available


    February 2024
  19. MARGOL AS, Molinaro AM, Onar-Thomas A, Resnick A, et al
    Use of External Control Cohorts in Pediatric Brain Tumor Clinical Trials.
    J Clin Oncol. 2024 Feb 23:JCO2301084. doi: 10.1200/JCO.23.01084.
    PubMed     Abstract available


  20. WU J, Heidelberg RE, Gajjar A
    Adolescents and Young Adults With Cancer: CNS Tumors.
    J Clin Oncol. 2024;42:686-695.
    PubMed     Abstract available


  21. ARRILLAGA-ROMANY I, Gardner SL, Odia Y, Aguilera D, et al
    ONC201 (Dordaviprone) in Recurrent H3 K27M-Mutant Diffuse Midline Glioma.
    J Clin Oncol. 2024 Feb 9:JCO2301134. doi: 10.1200/JCO.23.01134.
    PubMed     Abstract available


    December 2023
  22. DE VIS JB, Cmelak AJ, Osmundson EC
    Chemoimmunotherapy for Untreated Lung Cancer Brain Metastases: Systemic Before Local Therapy?
    J Clin Oncol. 2023 Dec 11:JCO2302151. doi: 10.1200/JCO.23.02151.
    PubMed    


  23. LEHRER EJ, Trifiletti DM, Fadul CE, Brown PD, et al
    Chemoimmunotherapy for Untreated Lung Cancer Brain Metastases: A Reason for Optimism While Avoiding Overreaching Interpretations.
    J Clin Oncol. 2023 Dec 11:JCO2301876. doi: 10.1200/JCO.23.01876.
    PubMed    


  24. JANNE PA, Planchard D, Kobayashi K, Cheng Y, et al
    CNS Efficacy of Osimertinib With or Without Chemotherapy in Epidermal Growth Factor Receptor-Mutated Advanced Non-Small-Cell Lung Cancer.
    J Clin Oncol. 2023 Dec 2:JCO2302219. doi: 10.1200/JCO.23.02219.
    PubMed     Abstract available


    November 2023
  25. HAAS-KOGAN DA, Aboian MS, Minturn JE, Leary SES, et al
    Everolimus for Children With Recurrent or Progressive Low-Grade Glioma: Results From the Phase II PNOC001 Trial.
    J Clin Oncol. 2023 Nov 17:JCO2301838. doi: 10.1200/JCO.23.01838.
    PubMed     Abstract available


  26. RUDIN CM, Liu SV, Soo RA, Lu S, et al
    SKYSCRAPER-02: Tiragolumab in Combination With Atezolizumab Plus Chemotherapy in Untreated Extensive-Stage Small-Cell Lung Cancer.
    J Clin Oncol. 2023 Nov 17:JCO2301363. doi: 10.1200/JCO.23.01363.
    PubMed     Abstract available


  27. FRIEDMAN HS, Prados MD, Wen PY, Mikkelsen T, et al
    Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma.
    J Clin Oncol. 2023;41:4945-4952.
    PubMed     Abstract available


  28. MELLINGHOFF IK
    Flashback Foreword: Bevacizumab and Irinotecan in Recurrent Glioblastoma.
    J Clin Oncol. 2023;41:4943-4944.
    PubMed    


    October 2023
  29. LEWIS KL, Jakobsen LH, Villa D, Smedby KE, et al
    High-Dose Methotrexate as CNS Prophylaxis in High-Risk Aggressive B-Cell Lymphoma.
    J Clin Oncol. 2023 Oct 5:JCO2300365. doi: 10.1200/JCO.23.00365.
    PubMed     Abstract available


    September 2023
  30. WEN PY, van den Bent M, Youssef G, Cloughesy TF, et al
    RANO 2.0: Update to the Response Assessment in Neuro-Oncology Criteria for High- and Low-Grade Gliomas in Adults.
    J Clin Oncol. 2023 Sep 29:JCO2301059. doi: 10.1200/JCO.23.01059.
    PubMed     Abstract available


  31. BANU MA, McKhann GM
    Maximizing Extent of Resection for Noneloquent Glioblastoma: Fluorescent Dye or Intraoperative Magnetic Resonance Imaging?
    J Clin Oncol. 2023 Sep 18:JCO2300963. doi: 10.1200/JCO.23.00963.
    PubMed    


  32. RAHMAN R, Trippa L, Lee EQ, Arrillaga-Romany I, et al
    Inaugural Results of the Individualized Screening Trial of Innovative Glioblastoma Therapy: A Phase II Platform Trial for Newly Diagnosed Glioblastoma Using Bayesian Adaptive Randomization.
    J Clin Oncol. 2023 Sep 18:JCO2300493. doi: 10.1200/JCO.23.00493.
    PubMed     Abstract available


    August 2023
  33. HARGRAVE DR, Terashima K, Hara J, Kordes UR, et al
    Phase II Trial of Dabrafenib Plus Trametinib in Relapsed/Refractory BRAF V600-Mutant Pediatric High-Grade Glioma.
    J Clin Oncol. 2023 Aug 29:JCO2300558. doi: 10.1200/JCO.23.00558.
    PubMed     Abstract available


  34. LU BY, Goldberg SB
    Chemoimmunotherapy for Untreated Lung Cancer Brain Metastases: Systemic Before Local Therapy?
    J Clin Oncol. 2023 Aug 21:JCO2301323. doi: 10.1200/JCO.23.01323.
    PubMed    


  35. NADAL E, Rodriguez-Abreu D, Simo M, Massuti B, et al
    Phase II Trial of Atezolizumab Combined With Carboplatin and Pemetrexed for Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer With Untreated Brain Metastases (Atezo-Brain, GECP17/05).
    J Clin Oncol. 2023 Aug 21:JCO2202561. doi: 10.1200/JCO.22.02561.
    PubMed     Abstract available


    June 2023
  36. RODER C, Stummer W, Coburger J, Scherer M, et al
    Intraoperative MRI-Guided Resection Is Not Superior to 5-Aminolevulinic Acid Guidance in Newly Diagnosed Glioblastoma: A Prospective Controlled Multicenter Clinical Trial.
    J Clin Oncol. 2023 Jun 19:JCO2201862. doi: 10.1200/JCO.22.01862.
    PubMed     Abstract available


  37. NEGRAO MV, Spira AI, Heist RS, Janne PA, et al
    Intracranial Efficacy of Adagrasib in Patients From the KRYSTAL-1 Trial With KRAS(G12C)-Mutated Non-Small-Cell Lung Cancer Who Have Untreated CNS Metastases.
    J Clin Oncol. 2023 Jun 16:JCO2300046. doi: 10.1200/JCO.23.00046.
    PubMed     Abstract available


  38. DUMMER R, Corrie P, Gutzmer R, Meniawy TM, et al
    First-Line, Fixed-Duration Nivolumab Plus Ipilimumab Followed by Nivolumab in Clinically Diverse Patient Populations With Unresectable Stage III or IV Melanoma: CheckMate 401.
    J Clin Oncol. 2023 Jun 12:JCO2202199. doi: 10.1200/JCO.22.02199.
    PubMed     Abstract available


    May 2023
  39. WARREN KE, Vezina G, Krailo M, Springer L, et al
    Phase II Randomized Trial of Lenalidomide in Children With Pilocytic Astrocytomas and Optic Pathway Gliomas: A Report From the Children's Oncology Group.
    J Clin Oncol. 2023 May 1:JCO2201777. doi: 10.1200/JCO.22.01777.
    PubMed     Abstract available


    April 2023
  40. HSU TW, Liang CS, Tsai SJ, Bai YM, et al
    Risk of Major Psychiatric Disorders Among Children and Adolescents Surviving Malignancies: A Nationwide Longitudinal Study.
    J Clin Oncol. 2023;41:2054-2066.
    PubMed     Abstract available


  41. YOUSSEF G, Rahman R, Bay C, Wang W, et al
    Evaluation of Standard Response Assessment in Neuro-Oncology, Modified Response Assessment in Neuro-Oncology, and Immunotherapy Response Assessment in Neuro-Oncology in Newly Diagnosed and Recurrent Glioblastoma.
    J Clin Oncol. 2023 Apr 7:JCO2201579. doi: 10.1200/JCO.22.01579.
    PubMed     Abstract available


    March 2023
  42. MUTTER JA, Alig SK, Esfahani MS, Lauer EM, et al
    Circulating Tumor DNA Profiling for Detection, Risk Stratification, and Classification of Brain Lymphomas.
    J Clin Oncol. 2023;41:1684-1694.
    PubMed     Abstract available


    February 2023
  43. DIEZ VALLE R
    Long-Term Outcomes in Resected IDH-Mutant Subtypes of Diffuse Low-Grade Glioma.
    J Clin Oncol. 2023 Feb 28:JCO2202428. doi: 10.1200/JCO.22.02428.
    PubMed    


    January 2023
  44. GROMMES C
    Circulating Tumor DNA in the Blood: A New Frontier in Primary CNS Lymphoma?
    J Clin Oncol. 2023 Jan 20:JCO2202605. doi: 10.1200/JCO.22.02605.
    PubMed    


Thank you for your interest in scientific medicine.


AMEDEO Neoplasms of the CNS is free of charge.