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Articles published in J Clin Oncol

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    March 2019
  1. CHANG SM, Messersmith H, Ahluwalia M, Andrews D, et al
    Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines.
    J Clin Oncol. 2019 Mar 18:JCO1802085. doi: 10.1200/JCO.18.02085.
    PubMed     Text format     Abstract available


  2. FREEDMAN RA, Gelman RS, Anders CK, Melisko ME, et al
    TBCRC 022: A Phase II Trial of Neratinib and Capecitabine for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases.
    J Clin Oncol. 2019 Mar 12:JCO1801511. doi: 10.1200/JCO.18.01511.
    PubMed     Text format     Abstract available


    February 2019
  3. SHINDE A, Li R, Amini A, Glaser S, et al
    Can Immunotherapy Replace Radiotherapy in Melanoma Brain Metastases?
    J Clin Oncol. 2019 Feb 26:JCO1801982. doi: 10.1200/JCO.18.01982.
    PubMed     Text format    


  4. SALLOUM R, Chen Y, Yasui Y, Packer R, et al
    Late Morbidity and Mortality Among Medulloblastoma Survivors Diagnosed Across Three Decades: A Report From the Childhood Cancer Survivor Study.
    J Clin Oncol. 2019 Feb 7:JCO1800969. doi: 10.1200/JCO.18.00969.
    PubMed     Text format     Abstract available


  5. WEN PY, Touat M, Alexander BM, Mellinghoff IK, et al
    Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial.
    J Clin Oncol. 2019 Feb 4:JCO1801207. doi: 10.1200/JCO.18.01207.
    PubMed     Text format     Abstract available


    November 2018
  6. KLUGER HM, Chiang V, Mahajan A, Zito CR, et al
    Long-Term Survival of Patients With Melanoma With Active Brain Metastases Treated With Pembrolizumab on a Phase II Trial.
    J Clin Oncol. 2018 Nov 8:JCO1800204. doi: 10.1200/JCO.18.00204.
    PubMed     Text format     Abstract available


    October 2018
  7. KALEY T, Touat M, Subbiah V, Hollebecque A, et al
    BRAF Inhibition in BRAF(V600)-Mutant Gliomas: Results From the VE-BASKET Study.
    J Clin Oncol. 2018 Oct 23:JCO2018789990. doi: 10.1200/JCO.2018.78.9990.
    PubMed     Text format     Abstract available


  8. MEHTA MP, Kotecha R
    Postoperative Management of Resected Brain Metastases: When Can Radiotherapy Be Deferred?
    J Clin Oncol. 2018 Oct 8:JCO2018793232. doi: 10.1200/JCO.2018.79.3232.
    PubMed     Text format     Abstract available


    August 2018
  9. VATNER RE, Niemierko A, Misra M, Weyman EA, et al
    Endocrine Deficiency as a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors.
    J Clin Oncol. 2018 Aug 17:JCO2018781492. doi: 10.1200/JCO.2018.78.1492.
    PubMed     Text format     Abstract available


    June 2018
  10. RAMAKRISHNA N, Temin S, Chandarlapaty S, Crews JR, et al
    Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases: ASCO Clinical Practice Guideline Update.
    J Clin Oncol. 2018 Jun 25:JCO2018792713. doi: 10.1200/JCO.2018.79.2713.
    PubMed     Text format     Abstract available


  11. KAYAMA T, Sato S, Sakurada K, Mizusawa J, et al
    Effects of Surgery With Salvage Stereotactic Radiosurgery Versus Surgery With Whole-Brain Radiation Therapy in Patients With One to Four Brain Metastases (JCOG0504): A Phase III, Noninferiority, Randomized Controlled Trial.
    J Clin Oncol. 2018 Jun 20:JCO2018786186. doi: 10.1200/JCO.2018.78.6186.
    PubMed     Text format     Abstract available


    May 2018
  12. CAMIDGE DR, Kim DW, Tiseo M, Langer CJ, et al
    Exploratory Analysis of Brigatinib Activity in Patients With Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer and Brain Metastases in Two Clinical Trials.
    J Clin Oncol. 2018 May 16:JCO2017775841. doi: 10.1200/JCO.2017.77.5841.
    PubMed     Text format     Abstract available


  13. HOFFMAN LM, Veldhuijzen van Zanten SEM, Colditz N, Baugh J, et al
    Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
    J Clin Oncol. 2018 May 10:JCO2017759308. doi: 10.1200/JCO.2017.75.9308.
    PubMed     Text format     Abstract available


    April 2018
  14. OMURO A, Beal K, McNeill K, Young RJ, et al
    Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas.
    J Clin Oncol. 2018 Apr 23:JCO2017769992. doi: 10.1200/JCO.2017.76.9992.
    PubMed     Text format     Abstract available


    February 2018
  15. FORSYTH PA, Abate-Daga D
    Oncolytic Virotherapy for Malignant Gliomas.
    J Clin Oncol. 2018 Feb 13:JCO2017773192. doi: 10.1200/JCO.2017.77.3192.
    PubMed     Text format    


  16. LANG FF, Conrad C, Gomez-Manzano C, Yung WKA, et al
    Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.
    J Clin Oncol. 2018 Feb 12:JCO2017758219. doi: 10.1200/JCO.2017.75.8219.
    PubMed     Text format     Abstract available


  17. GRILL J, Massimino M, Bouffet E, Azizi AA, et al
    Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma.
    J Clin Oncol. 2018 Feb 7:JCO2017760611. doi: 10.1200/JCO.2017.76.0611.
    PubMed     Text format     Abstract available


    December 2017
  18. BROWN PD, Ahluwalia MS, Khan OH, Asher AL, et al
    Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution?
    J Clin Oncol. 2017 Dec 22:JCO2017759589. doi: 10.1200/JCO.2017.75.9589.
    PubMed     Text format     Abstract available


    November 2017
  19. JONES DTW, Witt O, Pfister SM
    BRAF V600E Status Alone Is Not Sufficient as a Prognostic Biomarker in Pediatric Low-Grade Glioma.
    J Clin Oncol. 2017 Nov 15:JCO2017758987. doi: 10.1200/JCO.2017.75.8987.
    PubMed     Text format    


  20. WANG X, Sun CL, Hageman L, Smith K, et al
    Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study.
    J Clin Oncol. 2017;35:3688-3696.
    PubMed     Text format     Abstract available


    October 2017
  21. LIN NU, Prowell T, Tan AR, Kozak M, et al
    Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology-Friends of Cancer Research Brain Metastases Working Group.
    J Clin Oncol. 2017 Oct 2:JCO2017740761. doi: 10.1200/JCO.2017.74.0761.
    PubMed     Text format     Abstract available


  22. MOK TSK, Kim SW, Wu YL, Nakagawa K, et al
    Gefitinib Plus Chemotherapy Versus Chemotherapy in Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer Resistant to First-Line Gefitinib (IMPRESS): Overall Survival and Biomarker Analyses.
    J Clin Oncol. 2017 Oct 2:JCO2017739250. doi: 10.1200/JCO.2017.73.9250.
    PubMed     Text format     Abstract available


    July 2017
  23. LASSALETTA A, Zapotocky M, Mistry M, Ramaswamy V, et al
    Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.
    J Clin Oncol. 2017 Jul 20:JCO2016718726. doi: 10.1200/JCO.2016.71.8726.
    PubMed     Text format     Abstract available


  24. WEN PY, Chang SM, Van den Bent MJ, Vogelbaum MA, et al
    Response Assessment in Neuro-Oncology Clinical Trials.
    J Clin Oncol. 2017;35:2439-2449.
    PubMed     Text format     Abstract available


  25. VAN DEN BENT MJ, Smits M, Kros JM, Chang SM, et al
    Diffuse Infiltrating Oligodendroglioma and Astrocytoma.
    J Clin Oncol. 2017;35:2394-2401.
    PubMed     Text format     Abstract available


  26. CAMPIAN J, Gutmann DH
    CNS Tumors in Neurofibromatosis.
    J Clin Oncol. 2017;35:2378-2385.
    PubMed     Text format     Abstract available


  27. MERCHANT TE
    Current Clinical Challenges in Childhood Ependymoma: A Focused Review.
    J Clin Oncol. 2017;35:2364-2369.
    PubMed     Text format     Abstract available


  28. TEEPEN JC, van Leeuwen FE, Tissing WJ, van Dulmen-den Broeder E, et al
    Long-Term Risk of Subsequent Malignant Neoplasms After Treatment of Childhood Cancer in the DCOG LATER Study Cohort: Role of Chemotherapy.
    J Clin Oncol. 2017;35:2288-2298.
    PubMed     Text format     Abstract available


    June 2017
  29. PARADA LF, Dirks PB, Wechsler-Reya RJ
    Brain Tumor Stem Cells Remain in Play.
    J Clin Oncol. 2017 Jun 22:JCO2017739540. doi: 10.1200/JCO.2017.73.9540.
    PubMed     Text format    


  30. MELLINGHOFF IK, Gilbertson RJ
    Brain Tumors: Challenges and Opportunities to Cure.
    J Clin Oncol. 2017 Jun 22:JCO2017742965. doi: 10.1200/JCO.2017.74.2965.
    PubMed     Text format    


  31. RAMASWAMY V, Taylor MD
    Medulloblastoma: From Myth to Molecular.
    J Clin Oncol. 2017 Jun 22:JCO2017727842. doi: 10.1200/JCO.2017.72.7842.
    PubMed     Text format     Abstract available


  32. ALEXANDER BM, Cloughesy TF
    Adult Glioblastoma.
    J Clin Oncol. 2017 Jun 22:JCO2017730119. doi: 10.1200/JCO.2017.73.0119.
    PubMed     Text format     Abstract available


  33. MACK SC, Northcott PA
    Genomic Analysis of Childhood Brain Tumors: Methods for Genome-Wide Discovery and Precision Medicine Become Mainstream.
    J Clin Oncol. 2017 Jun 22:JCO2017729921. doi: 10.1200/JCO.2017.72.9921.
    PubMed     Text format     Abstract available


  34. SAMPSON JH, Maus MV, June CH
    Immunotherapy for Brain Tumors.
    J Clin Oncol. 2017 Jun 22:JCO2017728089. doi: 10.1200/JCO.2017.72.8089.
    PubMed     Text format     Abstract available


  35. BRINDLE KM, Izquierdo-Garcia JL, Lewis DY, Mair RJ, et al
    Brain Tumor Imaging.
    J Clin Oncol. 2017 Jun 22:JCO2017727636. doi: 10.1200/JCO.2017.72.7636.
    PubMed     Text format     Abstract available


  36. STURM D, Pfister SM, Jones DTW
    Pediatric Gliomas: Current Concepts on Diagnosis, Biology, and Clinical Management.
    J Clin Oncol. 2017 Jun 22:JCO2017730242. doi: 10.1200/JCO.2017.73.0242.
    PubMed     Text format     Abstract available


  37. DIAMANDIS P, Aldape KD
    Insights From Molecular Profiling of Adult Glioma.
    J Clin Oncol. 2017 Jun 22:JCO2017739516. doi: 10.1200/JCO.2017.73.9516.
    PubMed     Text format     Abstract available


  38. GROMMES C, DeAngelis LM
    Primary CNS Lymphoma.
    J Clin Oncol. 2017 Jun 22:JCO2017727602. doi: 10.1200/JCO.2017.72.7602.
    PubMed     Text format     Abstract available


    May 2017
  39. WINICK N, Devidas M, Chen S, Maloney K, et al
    Impact of Initial CSF Findings on Outcome Among Patients With National Cancer Institute Standard- and High-Risk B-Cell Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group.
    J Clin Oncol. 2017 May 23:JCO2016714774. doi: 10.1200/JCO.2016.71.4774.
    PubMed     Text format     Abstract available


  40. LIM SM, Kim HR, Lee JS, Lee KH, et al
    Open-Label, Multicenter, Phase II Study of Ceritinib in Patients With Non-Small-Cell Lung Cancer Harboring ROS1 Rearrangement.
    J Clin Oncol. 2017 May 18:JCO2016713701. doi: 10.1200/JCO.2016.71.3701.
    PubMed     Text format     Abstract available


  41. CHALMERS A, Akerley W
    Retrospective, Multi-Institutional Analysis of Sequential Treatment of Brain Metastases in Treatment-Naive, Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer Should Not Define the Standard of Practice.
    J Clin Oncol. 2017 May 8:JCO2017727255. doi: 10.1200/JCO.2017.72.7255.
    PubMed     Text format    


  42. KIM DW, Tiseo M, Ahn MJ, Reckamp KL, et al
    Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial.
    J Clin Oncol. 2017 May 5:JCO2016715904. doi: 10.1200/JCO.2016.71.5904.
    PubMed     Text format     Abstract available


    April 2017
  43. PAGLIARO LC
    Role of High-Dose Chemotherapy With Autologous Stem-Cell Rescue in Men With Previously Treated Germ Cell Tumors.
    J Clin Oncol. 2017;35:1036-1040.
    PubMed     Text format     Abstract available


    March 2017
  44. BOWERS DC, Moskowitz CS, Chou JF, Mazewski CM, et al
    Morbidity and Mortality Associated With Meningioma After Cranial Radiotherapy: A Report From the Childhood Cancer Survivor Study.
    J Clin Oncol. 2017 Mar 24:JCO2016701896. doi: 10.1200/JCO.2016.70.1896.
    PubMed     Text format     Abstract available


    January 2017
  45. MAGNUSON WJ, Lester-Coll NH, Wu AJ, Yang TJ, et al
    Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naive Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis.
    J Clin Oncol. 2017 Jan 23:JCO2016697144. doi: 10.1200/JCO.2016.69.7144.
    PubMed     Text format     Abstract available


  46. ZHOU L, Deng L, Lu Y
    Epidermal Growth Factor Receptor Mutations in Non-Small-Cell Lung Cancer With Brain Metastasis: Can Up-Front Radiation Therapy Be Deferred or Withheld?
    J Clin Oncol. 2017 Jan 23:JCO2016715706. doi: 10.1200/JCO.2016.71.5706.
    PubMed     Text format    


    December 2016
  47. MOLITORIS JK, Edelman MJ, Regine WF, Feigenberg SJ, et al
    Whole-Brain Radiation in the Treatment of Brain Metastases in ALK-Positive Non-Small-Cell Lung Cancer.
    J Clin Oncol. 2016 Dec 28:JCO2016697227.
    PubMed     Text format    


  48. CLEMENT SC, Schouten-van Meeteren AY, Boot AM, Claahsen-van der Grinten HL, et al
    Prevalence and Risk Factors of Early Endocrine Disorders in Childhood Brain Tumor Survivors: A Nationwide, Multicenter Study.
    J Clin Oncol. 2016;34:4362-4370.
    PubMed     Text format     Abstract available


  49. CLOUGHESY T, Finocchiaro G, Belda-Iniesta C, Recht L, et al
    Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguanine-DNA M
    J Clin Oncol. 2016 Dec 5:JCO2015647685.
    PubMed     Text format     Abstract available


  50. WARDAK Z, Choy H
    Improving Treatment Options for Brain Metastases From ALK-Positive Non-Small-Cell Lung Cancer.
    J Clin Oncol. 2016;34:4064-4065.
    PubMed     Text format    


  51. VON BUEREN AO, Kortmann RD, von Hoff K, Friedrich C, et al
    Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters.
    J Clin Oncol. 2016;34:4151-4160.
    PubMed     Text format     Abstract available


  52. GADGEEL SM, Shaw AT, Govindan R, Gandhi L, et al
    Pooled Analysis of CNS Response to Alectinib in Two Studies of Pretreated Patients With ALK-Positive Non-Small-Cell Lung Cancer.
    J Clin Oncol. 2016;34:4079-4085.
    PubMed     Text format     Abstract available


    November 2016
  53. SULMAN EP, Ismaila N, Armstrong TS, Tsien C, et al
    Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline.
    J Clin Oncol. 2016 Nov 28:JCO2016707562.
    PubMed     Text format     Abstract available


  54. CHOI C, Raisanen JM, Ganji SK, Zhang S, et al
    Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma.
    J Clin Oncol. 2016;34:4030-4039.
    PubMed     Text format     Abstract available


    July 2016
  55. CRINO L, Ahn MJ, De Marinis F, Groen HJ, et al
    Multicenter Phase II Study of Whole-Body and Intracranial Activity With Ceritinib in Patients With ALK-Rearranged Non-Small-Cell Lung Cancer Previously Treated With Chemotherapy and Crizotinib: Results From ASCEND-2.
    J Clin Oncol. 2016 Jul 18. pii: JCO655936.
    PubMed     Text format     Abstract available


  56. SCHMITZ N, Zeynalova S, Nickelsen M, Kansara R, et al
    CNS International Prognostic Index: A Risk Model for CNS Relapse in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP.
    J Clin Oncol. 2016 Jul 5. pii: JCO656520.
    PubMed     Text format     Abstract available


    April 2016
  57. COPUR MS, Ramaekers R, Clark D, Norvell M, et al
    Is It Time to Reconsider Prophylactic Cranial Radiation in Non-Small-Cell Lung Cancer?
    J Clin Oncol. 2016 Apr 25. pii: JCO652974.
    PubMed     Text format    


    March 2016
  58. GLASS J, Won M, Schultz CJ, Brat D, et al
    Phase I and II Study of Induction Chemotherapy With Methotrexate, Rituximab, and Temozolomide, Followed By Whole-Brain Radiotherapy and Postirradiation Temozolomide for Primary CNS Lymphoma: NRG Oncology RTOG 0227.
    J Clin Oncol. 2016 Mar 28. pii: JCO648634.
    PubMed     Text format     Abstract available


  59. SOLOMON BJ, Cappuzzo F, Felip E, Blackhall FH, et al
    Intracranial Efficacy of Crizotinib Versus Chemotherapy in Patients With Advanced ALK-Positive Non-Small-Cell Lung Cancer: Results From PROFILE 1014.
    J Clin Oncol. 2016 Mar 28. pii: JCO635888.
    PubMed     Text format     Abstract available


  60. KORFEL A, Schlegel U, Herrlinger U, Dreyling M, et al
    Phase II Trial of Temsirolimus for Relapsed/Refractory Primary CNS Lymphoma.
    J Clin Oncol. 2016 Mar 14. pii: JCO649897.
    PubMed     Text format     Abstract available


    January 2016
  61. BERNSTEIN LJ, Mason WP, Laperriere N, Chung C, et al
    Cognitive rehabilitation for brain tumor survivors: A pilot study.
    J Clin Oncol. 2016;34.
    PubMed     Text format     Abstract available


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