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COVID-19

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September 2026
1. HAN D, Beurel E
   The spike protein S1 of SARS-CoV-2 promotes Th17 cell-dependent stress-induced depressive-like behaviors in mice.
   Life Sci. 2026 Sep 8:124672. doi: 10.1016/j.lfs.2026.124672.
   PubMed     Abstract available
   
   
   August 2026
2. ZANG R, Ren Y, Wang J, Le Z, et al
   SARS-CoV-2 nucleocapsid protein drives pulmonary injury by enhancing GRP75-dependent ER-mitochondria tethering and reprogramming of alveolar macrophages.
   Life Sci. 2026 Aug 8:124625. doi: 10.1016/j.lfs.2026.124625.
   PubMed     Abstract available
   
   
   April 2026
3. BARTOLOMEO CS, Lemes RMR, Morais RL, Pereria GC, et al
   Corrigendum to "SARS-CoV-2 infection and replication kinetics in different human cell types: The role of autophagy, cellular metabolism and ACE2 expression" [Life Sciences 308 (2022) 120930].
   Life Sci. 2026 Apr 9:124367. doi: 10.1016/j.lfs.2026.124367.
   PubMed    
   
   
   March 2026
4. CHEN W, Ji MC, Jung E, Shin JS, et al
   Broad-spectrum coronavirus inhibition by RSV fusion inhibitors targeting six-helix bundle formation.
   Life Sci. 2026 Mar 31:124357. doi: 10.1016/j.lfs.2026.124357.
   PubMed     Abstract available
   
   
   April 2025
5. AZEEM M, Cancemi P, Mukhtar F, Marino S, et al
   Efficacy and limitations of SARS-CoV-2 vaccines - A systematic review.
   Life Sci. 2025;371:123610.
   PubMed     Abstract available
   
   
   March 2025
6. DUERR GD, Hamiko M, Beer J, Nattermann J, et al
   The interplay between COVID-19 and heart disease: Unravelling a complex connection.
   Life Sci. 2025 Mar 3:123524. doi: 10.1016/j.lfs.2025.123524.
   PubMed     Abstract available
   
   
   January 2025
7. DE SOUZA ALG, da Silva Rosa Alves AL, de Sousa JC, Barbosa NC, et al
   Inactivated SARS-CoV-2 induces acute skeletal muscle damage in human K18-hACE2 transgenic mice.
   Life Sci. 2025 Jan 18:123404. doi: 10.1016/j.lfs.2025.123404.
   PubMed     Abstract available
   
   
   
8. SHAFQAT A, Li M, Zakirullah, Liu F, et al
   A comprehensive review of research advances in the study of lactoferrin to treat viral infections.
   Life Sci. 2025;361:123340.
   PubMed     Abstract available
   
   
   
9. CHOPRA A, Franko N, Chow EJ
   Navigating neurologic post-COVID-19 conditions in adults: Management strategies for cognitive dysfunction, headaches and neuropathies.
   Life Sci. 2025;362:123374.
   PubMed     Abstract available
   
   
   December 2024
10. OATIS D, Balta C, Herman H, Ciceu A, et al
    The interplay between lung galectins and pro-fibrotic markers in post-COVID-19 fibrogenesis: A pilot study.
    Life Sci. 2024 Dec 19:123326. doi: 10.1016/j.lfs.2024.123326.
    PubMed     Abstract available
    
    
    November 2024
11. HERRING TE, Chopra A, Friedly JL, Bender JA, et al
    Post traumatic stress and sleep disorders in long COVID: Patient management and treatment.
    Life Sci. 2024;357:123081.
    PubMed     Abstract available
    
    
    
12. ASHRAF MS, Tuli K, Moiz S, Sharma SK, et al
    AMP kinase: A promising therapeutic drug target for post-COVID-19 complications.
    Life Sci. 2024;359:123202.
    PubMed     Abstract available
    
    
    October 2024
13. WANG N, Fan H, Wang Y, Shu C, et al
    The hybrid immunity defined by weaker immune imprinting of people living with HIV has a stronger neutralizing response against Omicron variants. A suggested explanation for fewer symptoms in people living with HIV after SARS-CoV-2 variants breakthroug
    Life Sci. 2024 Oct 29:123197. doi: 10.1016/j.lfs.2024.123197.
    PubMed     Abstract available
    
    
    
14. MARANGI M, Boughattas S, Benslimane F
    Gut microbiome profile to the level species in diarrheic protozoan-carrier patients in Italy.
    Life Sci. 2024 Oct 25:123182. doi: 10.1016/j.lfs.2024.123182.
    PubMed     Abstract available
    
    
    
15. YU LC
    Gastrointestinal pathophysiology in long COVID: Exploring roles of microbiota dysbiosis and serotonin dysregulation in post-infectious bowel symptoms.
    Life Sci. 2024;358:123153.
    PubMed     Abstract available
    
    
    
16. DOS SANTOS L, Favaroni Mendes Salgado Ribeiro LA, Febba Gomes AC, Azinheira Nobrega Cruz N, et al
    ACE and ACE2 activities and polymorphisms assessment: A populational study from Ipaussu (SP, Brazil) during the COVID-19 pandemic.
    Life Sci. 2024;358:123157.
    PubMed     Abstract available
    
    
    
17. TANG CC, Chang JC, Ho SJ, Liu WD, et al
    Exploring the characteristics and antecedents of clinically significant long COVID: A longitudinal cohort study.
    Life Sci. 2024;357:123114.
    PubMed     Abstract available
    
    
    September 2024
18. KING LR
    Gastrointestinal manifestations of long COVID.
    Life Sci. 2024 Sep 30:123100. doi: 10.1016/j.lfs.2024.123100.
    PubMed     Abstract available
    
    
    
19. SCHULTZ KR, McGrath S, Keary TA, Meng CK, et al
    A multidisciplinary approach to assessment and management of long COVID cognitive concerns.
    Life Sci. 2024;357:123068.
    PubMed     Abstract available
    
    
    
20. TUDORAN C, Tudoran M, Abu-Awwad A, Abu-Awwad SA, et al
    Sex-related differences concerning the profile and evolution of cardiovascular complications in patients with post-acute COVID-19 syndrome.
    Life Sci. 2024;356:123044.
    PubMed     Abstract available
    
    
    August 2024
21. VINUTHA M, Sharma UR, Swamy G, Rohini S, et al
    COVID-19-related liver injury: Mechanisms, diagnosis, management; its impact on pre-existing conditions, cancer and liver transplant: A comprehensive review.
    Life Sci. 2024 Aug 28:123022. doi: 10.1016/j.lfs.2024.123022.
    PubMed     Abstract available
    
    
    
22. BRODE WM, Melamed E
    A practical framework for Long COVID treatment in primary care.
    Life Sci. 2024;354:122977.
    PubMed     Abstract available
    
    
    
23. VOGEL JM, Pollack B, Spier E, McCorkell L, et al
    Designing and optimizing clinical trials for long COVID.
    Life Sci. 2024 Aug 12:122970. doi: 10.1016/j.lfs.2024.122970.
    PubMed     Abstract available
    
    
    
24. STRONGIN SR, Stelson E, Soares L, Sukhatme V, et al
    Using real-world data to accelerate the search for long COVID therapies.
    Life Sci. 2024;353:122940.
    PubMed     Abstract available
    
    
    July 2024
25. LI B, Bai J, Xiong Y, Guo D, et al
    Understanding the mechanisms and treatments of long COVID to address future public health risks.
    Life Sci. 2024 Jul 29:122938. doi: 10.1016/j.lfs.2024.122938.
    PubMed     Abstract available
    
    
    
26. LI X, Ding H, Feng G, Huang Y, et al
    Role of angiotensin converting enzyme in pathogenesis associated with immunity in cardiovascular diseases.
    Life Sci. 2024 Jul 8:122903. doi: 10.1016/j.lfs.2024.122903.
    PubMed     Abstract available
    
    
    
27. PEREIRA-SILVA GC, Cornelio CKCA, Pacheco G, Rochael NC, et al
    Diminazene aceturate inhibits the SARS-CoV-2 spike protein-induced inflammation involving leukocyte migration and DNA extracellular traps formation.
    Life Sci. 2024 Jul 8:122895. doi: 10.1016/j.lfs.2024.122895.
    PubMed     Abstract available
    
    
    June 2024
28. RAHEEM MA, Rahim MA, Gul I, Reyad-Ul-Ferdous M, et al
    COVID-19: Post infection implications in different age groups, mechanism, diagnosis, effective prevention, treatment, and recommendations.
    Life Sci. 2024 Jun 24:122861. doi: 10.1016/j.lfs.2024.122861.
    PubMed     Abstract available
    
    
    
29. ENDO HM, Bandeca SCS, Olchanheski LR, Schemczssen-Graeff Z, et al
    Probiotics and the reduction of SARS-CoV-2 infection through regulation of host cell calcium dynamics.
    Life Sci. 2024;350:122784.
    PubMed     Abstract available
    
    
    
30. HSIEH MS, Chen MY, Chang YS, Huang CS, et al
    Targeting the Neuropilin-1 receptor with Ovatodiolide and progress in using periodontal ligament organoids for COVID-19 research and therapy.
    Life Sci. 2024 Jun 3:122764. doi: 10.1016/j.lfs.2024.122764.
    PubMed     Abstract available
    
    
    May 2024
31. PETRY J, Weiser T, Griesbaum L, Schroder K, et al
    1.8-cineole prevents platelet activation and aggregation by activating the cAMP pathway via the adenosine A(2A) receptor.
    Life Sci. 2024 May 27:122746. doi: 10.1016/j.lfs.2024.122746.
    PubMed     Abstract available
    
    
    April 2024
32. LI Q, Peng G, Liu H, Wang L, et al
    Molecular mechanisms of secretory autophagy and its potential role in diseases.
    Life Sci. 2024 Apr 23:122653. doi: 10.1016/j.lfs.2024.122653.
    PubMed     Abstract available
    
    
    February 2024
33. YOUSEF M, Rob M, Varghese S, Rao S, et al
    The effect of microbiome therapy on COVID-19-induced gut dysbiosis: A narrative and systematic review.
    Life Sci. 2024;342:122535.
    PubMed     Abstract available
    
    
    December 2023
34. PORIA R, Kala D, Nagraik R, Dhir Y, et al
    Vaccine development: Current trends and technologies.
    Life Sci. 2023 Dec 7:122331. doi: 10.1016/j.lfs.2023.122331.
    PubMed     Abstract available
    
    
    November 2023
35. MORA-RODRIGUEZ JM, Sanchez BG, Bort A, Diaz-Yuste A, et al
    Diabetic individuals with COVID-19 exhibit reduced efficacy of gliptins in inhibiting dipeptidyl peptidase 4 (DPP4). A suggested explanation for increased COVID-19 susceptibility in patients with type 2 diabetes mellitus (T2DM).
    Life Sci. 2023;336:122292.
    PubMed     Abstract available
    
    
    
36. ZEYADA MS, Eraky SM, El-Shishtawy MM
    Trigonelline mitigates bleomycin-induced pulmonary inflammation and fibrosis: Insight into NLRP3 inflammasome and SPHK1/S1P/Hippo signaling modulation.
    Life Sci. 2023 Nov 17:122272. doi: 10.1016/j.lfs.2023.122272.
    PubMed     Abstract available
    
    
    October 2023
37. PETPIROON N, Netkueakul W, Sukrak K, Wang C, et al
    Development of lung tissue models and their applications.
    Life Sci. 2023 Oct 24:122208. doi: 10.1016/j.lfs.2023.122208.
    PubMed     Abstract available
    
    
    
38. KRASAEWES K, Chaiwarith R, Chattipakorn N, Chattipakorn SC, et al
    Profiles of gut microbiota associated with clinical outcomes in patients with different stages of SARS-CoV-2 infection.
    Life Sci. 2023;332:122136.
    PubMed     Abstract available
    
    
    September 2023
39. ZHONG HL, Li PZ, Li D, Guan CX, et al
    The role of vasoactive intestinal peptide in pulmonary diseases.
    Life Sci. 2023 Sep 22:122121. doi: 10.1016/j.lfs.2023.122121.
    PubMed     Abstract available
    
    
    
40. ROSA CP, Belo TCA, Santos NCM, Silva EN, et al
    Reactive oxygen species trigger inflammasome activation after intracellular microbial interaction.
    Life Sci. 2023;331:122076.
    PubMed     Abstract available
    
    
    July 2023
41. LU X, Mao T, Dai Y, Zhu L, et al
    Azithromycin exposure during pregnancy disturbs the fetal development and its characteristic of multi-organ toxicity.
    Life Sci. 2023;329:121985.
    PubMed     Abstract available
    
    
    
42. ISAZADEH A, Heris JA, Shahabi P, Mohammadinasab R, et al
    Pattern-recognition receptors (PRRs) in SARS-CoV-2.
    Life Sci. 2023;329:121940.
    PubMed     Abstract available
    
    
    June 2023
43. YAZDANPARAST S, Bakhtiyaridovvombaygi M, Mikanik F, Ahmadi R, et al
    Spotlight on contributory role of host immunogenetic profiling in SARS-CoV-2 infection: Susceptibility, severity, mortality, and vaccine effectiveness.
    Life Sci. 2023 Jun 30:121907. doi: 10.1016/j.lfs.2023.121907.
    PubMed     Abstract available
    
    
    May 2023
44. QUEIROZ-JUNIOR CM, Santos ACPM, Goncalves MR, Brito CB, et al
    Acute coronavirus infection triggers a TNF-dependent osteoporotic phenotype in mice.
    Life Sci. 2023 May 2:121750. doi: 10.1016/j.lfs.2023.121750.
    PubMed     Abstract available
    
    
    March 2023
45. DELDADEH N, Haghighat S, Omidi Z, Sarrami-Foroushani R, et al
    Anti-cancer effect of COVID-19 vaccines in 4T1 mice models.
    Life Sci. 2023 Mar 10:121569. doi: 10.1016/j.lfs.2023.121569.
    PubMed     Abstract available
    
    
    February 2023
46. SHER EK, Cosovic A, Dzidic-Krivic A, Farhat EK, et al
    Covid-19 a triggering factor of autoimmune and multi-inflammatory diseases.
    Life Sci. 2023 Feb 27:121531. doi: 10.1016/j.lfs.2023.121531.
    PubMed     Abstract available
    
    
    
47. GHORBANINEJAD M, Asadzadeh-Aghdaei H, Baharvand H, Meyfour A, et al
    Intestinal organoids: A versatile platform for modeling gastrointestinal diseases and monitoring epigenetic alterations.
    Life Sci. 2023 Feb 27:121506. doi: 10.1016/j.lfs.2023.121506.
    PubMed     Abstract available
    
    
    
48. EHTESHAMINIA Y, Jalali SF, Jadidi-Niaragh F, Enderami SE, et al
    Enhancement of immunogenicity and neutralizing responses against SARS-CoV-2 spike protein using the Fc fusion fragment.
    Life Sci. 2023 Feb 23:121525. doi: 10.1016/j.lfs.2023.121525.
    PubMed     Abstract available
    
    
    January 2023
49. SAXENA R, Sharma P, Kumar S, Agrawal N, et al
    Modulation of mitochondria by viral proteins.
    Life Sci. 2023;313:121271.
    PubMed     Abstract available
    
    
    
50. LIN F, Lin X, Fu B, Xiong Y, et al
    Functional studies of HLA and its role in SARS-CoV-2: Stimulating T cell response and vaccine development.
    Life Sci. 2023;315:121374.
    PubMed     Abstract available
    
    
    December 2022
51. HUSSEIN RM, Arafa EA, Raheem SA, Mohamed WR, et al
    Thymol protects against bleomycin-induced pulmonary fibrosis via abrogation of oxidative stress, inflammation, and modulation of miR-29a/TGF-beta and PI3K/Akt signaling in mice.
    Life Sci. 2022 Dec 19:121256. doi: 10.1016/j.lfs.2022.121256.
    PubMed     Abstract available
    
    
    October 2022
52. ANTAR SA, Saleh MA, Al-Karmalawy AA
    Investigating the possible mechanisms of pirfenidone to be targeted as a promising anti-inflammatory, anti-fibrotic, anti-oxidant, anti-apoptotic, anti-tumor, and/or anti-SARS-CoV-2.
    Life Sci. 2022;309:121048.
    PubMed     Abstract available
    
    
    September 2022
53. ALEKSOVA A, Fluca AL, Gagno G, Pierri A, et al
    Long-term effect of SARS-CoV-2 infection on cardiovascular outcomes and all-cause mortality.
    Life Sci. 2022 Sep 29:121018. doi: 10.1016/j.lfs.2022.121018.
    PubMed     Abstract available
    
    
    
54. HSU PC, Shahed-Al-Mahmud M
    SARS-CoV-2 mediated neurological disorders in COVID-19: Measuring the pathophysiology and immune response.
    Life Sci. 2022 Sep 20:120981. doi: 10.1016/j.lfs.2022.120981.
    PubMed     Abstract available
    
    
    
55. BARTOLOMEO CS, Lemes RMR, Morais RL, Pereria GC, et al
    SARS-CoV-2 infection and replication kinetics in different human cell types: The role of autophagy, cellular metabolism and ACE2 expression.
    Life Sci. 2022 Sep 5:120930. doi: 10.1016/j.lfs.2022.120930.
    PubMed     Abstract available
    
    
    August 2022
56. SHARIF-ASKARI FS, Hafezi S, Sharif-Askari NS, Alsayed HAH, et al
    Vitamin D modulates systemic inflammation in patients with severe COVID-19.
    Life Sci. 2022 Aug 23:120909. doi: 10.1016/j.lfs.2022.120909.
    PubMed     Abstract available
    
    
    
57. HOSSEINZADEH A, Bagherifard A, Koosha F, Amiri S, et al
    Melatonin effect on platelets and coagulation: Implications for a prophylactic indication in COVID-19.
    Life Sci. 2022;307:120866.
    PubMed     Abstract available
    
    
    July 2022
58. ALI MA, El-Tahan RA, Kamel MA, Matar NA, et al
    The diabetogenic effects of chronic supplementation of vitamin C or E in rats: Interplay between liver and adipose tissues transcriptional machinery of lipid metabolism.
    Life Sci. 2022 Jul 18:120812. doi: 10.1016/j.lfs.2022.120812.
    PubMed     Abstract available
    
    
    
59. MALEKINEJAD Z, Baghbanzadeh A, Nakhlband A, Baradaran B, et al
    Recent clinical findings on the role of kinase inhibitors in COVID-19 management.
    Life Sci. 2022 Jul 13:120809. doi: 10.1016/j.lfs.2022.120809.
    PubMed     Abstract available
    
    
    
60. MAZUMDER S, Bindu S, De R, Debsharma S, et al
    Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis.
    Life Sci. 2022 Jul 1:120753. doi: 10.1016/j.lfs.2022.120753.
    PubMed     Abstract available
    
    
    
61. PANDA M, Kalita E, Singh S, Kumar K, et al
    MiRNA-SARS-CoV-2 dialogue and prospective anti-COVID-19 therapies.
    Life Sci. 2022 Jul 1:120761. doi: 10.1016/j.lfs.2022.120761.
    PubMed     Abstract available
    
    
    June 2022
62. GUPTA A, Jayakumar MN, Saleh MA, Kannan M, et al
    SARS-CoV-2-infection induced growth factors play differential roles in COVID-19 pathogenesis.
    Life Sci. 2022 Jun 11:120703. doi: 10.1016/j.lfs.2022.120703.
    PubMed     Abstract available
    
    
    May 2022
63. PATIL PJ, Sutar SS, Usman M, Patil DN, et al
    Exploring bioactive peptides as potential therapeutic and biotechnology treasures: A contemporary perspective.
    Life Sci. 2022;301:120637.
    PubMed     Abstract available
    
    
    
64. FERNANDES MF, Chan JZ, Hung CCJ, Tomczewski MV, et al
    Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein.
    Life Sci. 2022;301:120624.
    PubMed     Abstract available
    
    
    
65. HUANG DY, Wang GM, Ke ZR, Zhou Y, et al
    Megakaryocytes in pulmonary diseases.
    Life Sci. 2022 May 1:120602. doi: 10.1016/j.lfs.2022.120602.
    PubMed     Abstract available
    
    
    April 2022
66. YOUNG LJ, Antwi-Boasiako S, Ferrall J, Wold LE, et al
    Genetic and non-genetic risk factors associated with atrial fibrillation.
    Life Sci. 2022;299:120529.
    PubMed     Abstract available
    
    
    March 2022
67. MAZIDIMORADI A, Alemzadeh E, Alemzadeh E, Salehiniya H, et al
    The effect of polyunsaturated fatty acids on the severity and mortality of COVID patients: A systematic review.
    Life Sci. 2022 Mar 28:120489. doi: 10.1016/j.lfs.2022.120489.
    PubMed     Abstract available
    
    
    
68. NADEALI Z, Rezaei FM, Aria H, Nikpour P, et al
    Possible role of pannexin 1 channels and purinergic receptors in the pathogenesis and mechanism of action of SARS-CoV-2 and therapeutic potential of targeting them in COVID-19.
    Life Sci. 2022 Mar 11:120482. doi: 10.1016/j.lfs.2022.120482.
    PubMed     Abstract available
    
    
    
69. MENENDEZ SG, Martin Gimenez VM, Holick MF, Barrantes FJ, et al
    COVID-19 and neurological sequelae: Vitamin D as a possible neuroprotective and/or neuroreparative agent.
    Life Sci. 2022;297:120464.
    PubMed     Abstract available
    
    

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