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Depression

Free Subscription Articles published in Am J Psychiatry Retrieve available abstracts of 83 articles: HTML format

Single Articles

October 2025
1. KALIN NH
   Adolescent Suicidality and Depression, Premenstrual Dysphoric Disorder, and Safety Issues Related to Ketamine and Esketamine Treatment.
   Am J Psychiatry. 2025;182:889-891.
   PubMed    
   
   
   
2. WEI SM, Wakim P, Martinez PE, Nieman LK, et al
   Differential Effects of Ovarian Steroids in Women With and Without Premenstrual Dysphoric Disorder: A Replication and Extension of Findings.
   Am J Psychiatry. 2025;182:922-934.
   PubMed     Abstract available
   
   
   
3. FOUNTOULAKIS KN, Saitis A, Schatzberg AF
   Esketamine Treatment for Depression in Adults: Response to Price et al. and Canuso et al.
   Am J Psychiatry. 2025;182:954-956.
   PubMed    
   
   
   
4. CANUSO CM, Bossie C, Fu DJ, Lane R, et al
   Comment on Esketamine Treatment for Depression in Adults: A PRISMA Systematic Review and Meta-Analysis.
   Am J Psychiatry. 2025;182:951-954.
   PubMed    
   
   
   
5. WHITTLE S, Rakesh D, Simmons JG, Schwartz O, et al
   Prospective Associations Between Structural Brain Development and Onset of Depressive Disorder During Adolescence and Emerging Adulthood.
   Am J Psychiatry. 2025;182:935-944.
   PubMed     Abstract available
   
   
   September 2025
6. LI SW, Kumpf KT, Urrutia J, Krystal JH, et al
   Ketamine for Depression, but at What Cost? A Review of Ketamine's Neurotoxic Effects From Preclinical and Human Studies.
   Am J Psychiatry. 2025 Sep 10:appiajp20250276. doi: 10.1176/appi.ajp.20250276.
   PubMed     Abstract available
   
   
   July 2025
7. AHN Y, Kim J, Jung K, Lee DJ, et al
   Relationship Between Problematic Alcohol Use and Various Psychiatric Disorders: A Genetically Informed Study.
   Am J Psychiatry. 2025;182:671-682.
   PubMed     Abstract available
   
   
   June 2025
8. FONZO GA, Doss MK, Nemeroff CB
   There's More Than One Way to Bring Health Back: Divergent Effects of Psilocybin and Escitalopram Treatment on Emotional Brain Function in Depression.
   Am J Psychiatry. 2025;182:512-515.
   PubMed    
   
   
   
9. KALIN NH
   Depression, Inflammation, and Postpartum Psychosis.
   Am J Psychiatry. 2025;182:501-503.
   PubMed    
   
   
   
10. SAVITZ J, Figueroa-Hall LK, Teague TK, Yeh HW, et al
    Systemic Inflammation and Anhedonic Responses to an Inflammatory Challenge in Adults With Major Depressive Disorder: A Randomized Controlled Trial.
    Am J Psychiatry. 2025;182:560-568.
    PubMed     Abstract available
    
    
    May 2025
11. CLAPP MA, Castro VM, Verhaak P, McCoy TH, et al
    Stratifying Risk for Postpartum Depression at Time of Hospital Discharge.
    Am J Psychiatry. 2025 May 19:appiajp20240381. doi: 10.1176/appi.ajp.20240381.
    PubMed     Abstract available
    
    
    
12. MILLER AH
    Advancing an Inflammatory Subtype of Major Depression.
    Am J Psychiatry. 2025 May 7:appiajp20250289. doi: 10.1176/appi.ajp.20250289.
    PubMed     Abstract available
    
    
    
13. WALL MB, Demetriou L, Giribaldi B, Roseman L, et al
    Reduced Brain Responsiveness to Emotional Stimuli With Escitalopram But Not Psilocybin Therapy for Depression.
    Am J Psychiatry. 2025 May 7:appiajp20230751. doi: 10.1176/appi.ajp.20230751.
    PubMed     Abstract available
    
    
    
14. RUGGIERO KJ, Andrews A, Davidson TM, Gavrilova Y, et al
    Randomized Controlled Trial of "Bounce Back Now," a Mobile App to Reduce Post-Disaster Symptoms of Posttraumatic Stress, Depressed Mood, and Sleep Disturbance.
    Am J Psychiatry. 2025;182:463-472.
    PubMed     Abstract available
    
    
    
15. TANG VM, Aaronson S, Abdelghani M, Baeken C, et al
    Assessment and Management of Concurrent Substance Use in Patients Receiving Repetitive Transcranial Magnetic Stimulation for Depressive, Obsessive-Compulsive, Psychotic, and Trauma-Related Disorders: A Delphi Consensus Study and Guideline.
    Am J Psychiatry. 2025;182:438-451.
    PubMed     Abstract available
    
    
    April 2025
16. CHEN L, Fukuda AM, Jiang S, Leuchter MK, et al
    Treating Depression With Repetitive Transcranial Magnetic Stimulation: A Clinician's Guide.
    Am J Psychiatry. 2025 Apr 30:appiajp20240859. doi: 10.1176/appi.ajp.20240859.
    PubMed     Abstract available
    
    
    March 2025
17. KALIN NH
    New Developments in the Treatment of Depression, OCD, and Schizophrenia.
    Am J Psychiatry. 2025;182:223-226.
    PubMed    
    
    
    
18. MATHEW SJ, Murphy N
    Six Years After Approval of Esketamine Nasal Spray for Serious Depression: Clinical Conundrums and Unanswered Questions.
    Am J Psychiatry. 2025;182:227-230.
    PubMed    
    
    
    
19. BRUNONI AR, Padberg F
    Spaced Transcranial Direct Current Stimulation for Depression: The Road Less Traveled.
    Am J Psychiatry. 2025;182:231-233.
    PubMed    
    
    
    February 2025
20. KING AC, Fischer AM, Cursio JF, Didier NA, et al
    Real-Time Assessment of Alcohol Reward, Stimulation, and Negative Affect in Individuals With and Without Alcohol Use Disorder and Depressive Disorders.
    Am J Psychiatry. 2025;182:187-197.
    PubMed     Abstract available
    
    
    
21. KYPRIOTAKIS G, Cinciripini PM, Green CE, Lawrence D, et al
    Effects of Varenicline, Bupropion, Nicotine Patch, and Placebo on Treating Smoking Among Persons With Current or Past Major Depressive Disorder: Secondary Analysis of a Double-Blind, Randomized, Placebo-Controlled Trial.
    Am J Psychiatry. 2025;182:174-186.
    PubMed     Abstract available
    
    
    January 2025
22. FOUNTOULAKIS KN, Saitis A, Schatzberg AF
    Esketamine Treatment for Depression in Adults: A PRISMA Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2025 Jan 29:appiajp20240515. doi: 10.1176/appi.ajp.20240515.
    PubMed     Abstract available
    
    
    
23. COUTURE M, Desbeaumes Jodoin V, Bousseau E, Sarshoghi A, et al
    Spaced Transcranial Direct Current Stimulation for Major Depression.
    Am J Psychiatry. 2025 Jan 29:appiajp20240083. doi: 10.1176/appi.ajp.20240083.
    PubMed     Abstract available
    
    
    
24. MCINTYRE RS, Kwan ATH, Mansur RB, Oliveira-Maia AJ, et al
    Psychedelics for the Treatment of Psychiatric Disorders: Interpreting and Translating Available Evidence and Guidance for Future Research.
    Am J Psychiatry. 2025;182:21-32.
    PubMed     Abstract available
    
    
    
25. AARONSON ST, van der Vaart A, Miller T, LaPratt J, et al
    Single-Dose Psilocybin for Depression With Severe Treatment Resistance: An Open-Label Trial.
    Am J Psychiatry. 2025;182:104-113.
    PubMed     Abstract available
    
    
    
26. RAMAEKERS JG, Reckweg JT, Mason NL
    Benefits and Challenges of Ultra-Fast, Short-Acting Psychedelics in the Treatment of Depression.
    Am J Psychiatry. 2025;182:33-46.
    PubMed     Abstract available
    
    
    
27. FONZO GA, Wolfgang AS, Barksdale BR, Krystal JH, et al
    Psilocybin: From Psychiatric Pariah to Perceived Panacea.
    Am J Psychiatry. 2025;182:54-78.
    PubMed     Abstract available
    
    
    
28. KIRLIC N, Lennard-Jones M, Atli M, Malievskaia E, et al
    Compass Psychological Support Model for COMP360 Psilocybin Treatment of Serious Mental Health Conditions.
    Am J Psychiatry. 2025;182:126-132.
    PubMed     Abstract available
    
    
    December 2024
29. WIDOM CS, Courtney K, Do HH
    Pathways to Homelessness: Childhood Maltreatment and Psychiatric Symptoms Increase Risk of Homelessness.
    Am J Psychiatry. 2024;181:1103-1111.
    PubMed     Abstract available
    
    
    
30. GREY DK, Purcell JB, Buford KN, Schuster MA, et al
    Discrimination Exposure, Neural Reactivity to Stress, and Psychological Distress.
    Am J Psychiatry. 2024;181:1112-1126.
    PubMed     Abstract available
    
    
    October 2024
31. GALLUCCI J, Yu JC, Oliver LD, Nakua H, et al
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:910-919.
    PubMed     Abstract available
    
    
    
32. HWANG M, Brady R
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:858-860.
    PubMed    
    
    
    September 2024
33. SOARES CN
    Contraception, Intrauterine Systems, and Depression: Can We Spot the Real Perpetrator?
    Am J Psychiatry. 2024;181:789-792.
    PubMed    
    
    
    
34. MARTIN DM, Nikolin S
    "Closing the Loop" With Transcranial Electrical Stimulation for Depression.
    Am J Psychiatry. 2024;181:793-794.
    PubMed    
    
    
    
35. KASTER TS, Blumberger DM
    Positioning rTMS Within a Sequential Treatment Algorithm of Depression.
    Am J Psychiatry. 2024;181:781-783.
    PubMed    
    
    
    
36. KALIN NH
    Depression: Factors Contributing to Risk and Therapeutic Insights.
    Am J Psychiatry. 2024;181:777-780.
    PubMed    
    
    
    
37. DALHUISEN I, van Oostrom I, Spijker J, Wijnen B, et al
    rTMS as a Next Step in Antidepressant Nonresponders: A Randomized Comparison With Current Antidepressant Treatment Approaches.
    Am J Psychiatry. 2024;181:806-814.
    PubMed     Abstract available
    
    
    
38. SCHWIPPEL T, Pupillo F, Feldman Z, Walker C, et al
    Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder: An Open-Label Pilot Study.
    Am J Psychiatry. 2024;181:842-845.
    PubMed    
    
    
    
39. HESS EM, Greenstein DK, Hutchinson OL, Zarate CA, et al
    Entactogen Effects of Ketamine: A Reverse-Translational Study.
    Am J Psychiatry. 2024;181:815-823.
    PubMed     Abstract available
    
    
    August 2024
40. SALVATORE JE, Ohlsson H, Sundquist J, Sundquist K, et al
    Peer Social Genetic Effects and the Etiology of Substance Use Disorders, Major Depression, and Anxiety Disorder in a Swedish National Sample.
    Am J Psychiatry. 2024 Aug 7:appiajp20230358. doi: 10.1176/appi.ajp.20230358.
    PubMed     Abstract available
    
    
    July 2024
41. LARSEN SV, Mikkelsen AP, Ozenne B, Munk-Olsen T, et al
    Association Between Intrauterine System Hormone Dosage and Depression Risk.
    Am J Psychiatry. 2024 Jul 10:appiajp20230909. doi: 10.1176/appi.ajp.20230909.
    PubMed     Abstract available
    
    
    
42. POLIMANTI R
    Using Medical Records to Investigate the Genetics of Treatment-Resistant Depression Across Health Care Systems.
    Am J Psychiatry. 2024;181:569-571.
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43. AKIKI TJ, Abdallah CG
    Mapping the Depressed Brain Under Stress Using Multimodal Neuroimaging.
    Am J Psychiatry. 2024;181:578-580.
    PubMed    
    
    
    
44. ROHDE C, Ostergaard SD, Jefsen OH
    A Nationwide Target Trial Emulation Assessing the Risk of Antidepressant-Induced Mania Among Patients With Bipolar Depression.
    Am J Psychiatry. 2024;181:630-638.
    PubMed     Abstract available
    
    
    
45. JONSSON L, Horbeck E, Primerano A, Song J, et al
    Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder.
    Am J Psychiatry. 2024;181:620-629.
    PubMed     Abstract available
    
    
    May 2024
46. KANG J, Castro VM, Ripperger M, Venkatesh S, et al
    Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits.
    Am J Psychiatry. 2024 May 15:appiajp20230247. doi: 10.1176/appi.ajp.20230247.
    PubMed     Abstract available
    
    
    April 2024
47. BAUM ML, Widge AS, Carpenter LL, McDonald WM, et al
    Pharmacogenomic Clinical Support Tools for the Treatment of Depression.
    Am J Psychiatry. 2024 Apr 30:appiajp20230657. doi: 10.1176/appi.ajp.20230657.
    PubMed     Abstract available
    
    
    
48. IRONSIDE M, Duda JM, Moser AD, Holsen LM, et al
    Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects.
    Am J Psychiatry. 2024 Apr 30:appiajp20230382. doi: 10.1176/appi.ajp.20230382.
    PubMed     Abstract available
    
    
    
49. KAVIRAJAN H
    Neglect of Adverse Effects in Treatment Guidelines for Depression.
    Am J Psychiatry. 2024;181:342-345.
    PubMed    
    
    
    March 2024
50. STEFFENS DC
    Late-Life Depression, Antidepressant Treatment, and Cognition: The Short Haul and the Long Haul.
    Am J Psychiatry. 2024;181:183-185.
    PubMed    
    
    
    
51. PHILLIPS ML
    Multimodal Predictors of Treatment Response in Major Depressive Disorder: Advancing Personalized Medicine in Psychiatry.
    Am J Psychiatry. 2024;181:180-182.
    PubMed    
    
    
    
52. POIROT MG, Ruhe HG, Mutsaerts HMM, Maximov II, et al
    Treatment Response Prediction in Major Depressive Disorder Using Multimodal MRI and Clinical Data: Secondary Analysis of a Randomized Clinical Trial.
    Am J Psychiatry. 2024;181:223-233.
    PubMed     Abstract available
    
    
    February 2024
53. AINSWORTH NJ, Marawi T, Maslej MM, Blumberger DM, et al
    Cognitive Outcomes After Antidepressant Pharmacotherapy for Late-Life Depression: A Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2024 Feb 7:appiajp20230392. doi: 10.1176/appi.ajp.20230392.
    PubMed     Abstract available
    
    
    January 2024
54. KALIN NH
    Improving Clinical Outcomes and Informing New Interventions.
    Am J Psychiatry. 2024;181:1-3.
    PubMed    
    
    
    
55. WALASZEK A
    Optimizing the Treatment of Late-Life Depression.
    Am J Psychiatry. 2024;181:7-10.
    PubMed    
    
    
    
56. RUBINOW DR
    Suicide and the Menstrual Cycle.
    Am J Psychiatry. 2024;181:11-13.
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57. BATAIL JV, Feyder MT, Bentzley BS, Williams NR, et al
    An Avenue for Optimization of Theta Burst Stimulation Protocols? Comments on the FOUR-D Randomized Noninferiority Clinical Trial.
    Am J Psychiatry. 2024;181:68-70.
    PubMed    
    
    
    December 2023
58. KALIN NH
    Adversity and Resilience, Postpartum Depression, Suicide, and Racial/Ethnic Disparities.
    Am J Psychiatry. 2023;180:859-861.
    PubMed    
    
    
    
59. ADAMS JAM, Chandra P, Mehta D
    The First Large GWAS Meta-Analysis for Postpartum Depression.
    Am J Psychiatry. 2023;180:862-864.
    PubMed    
    
    
    
60. STOWE ZN
    Perinatal Mental Health: Advances and Opportunities.
    Am J Psychiatry. 2023;180:874-877.
    PubMed    
    
    
    October 2023
61. GUINTIVANO J, Byrne EM, Kiewa J, Yao S, et al
    Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression.
    Am J Psychiatry. 2023 Oct 18:appiajp20230053. doi: 10.1176/appi.ajp.20230053.
    PubMed     Abstract available
    
    
    
62. ISHTIAK-AHMED K, Musliner KL, Christensen KS, Mortensen EL, et al
    Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark.
    Am J Psychiatry. 2023 Oct 18:appiajp20230356. doi: 10.1176/appi.ajp.20230356.
    PubMed     Abstract available
    
    
    
63. SHACKMAN AJ, Gee DG
    Maternal Perinatal Stress Associated With Offspring Negative Emotionality, But the Underlying Mechanisms Remain Elusive.
    Am J Psychiatry. 2023;180:708-711.
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64. KALIN NH
    Stress, Heritability, and Genetic Factors Influencing Depression, PTSD, and Suicidal Behavior.
    Am J Psychiatry. 2023;180:699-702.
    PubMed    
    
    
    
65. LYNALL ME, McIntosh AM
    The Heterogeneity of Depression.
    Am J Psychiatry. 2023;180:703-704.
    PubMed    
    
    
    
66. NGUYEN TD, Kowalec K, Pasman J, Larsson H, et al
    Genetic Contribution to the Heterogeneity of Major Depressive Disorder: Evidence From a Sibling-Based Design Using Swedish National Registers.
    Am J Psychiatry. 2023;180:714-722.
    PubMed     Abstract available
    
    
    
67. FARHAT LC, Blakey R, Davey Smith G, Fujita A, et al
    Networks of Neurodevelopmental Traits, Socioenvironmental Factors, Emotional Dysregulation in Childhood, and Depressive Symptoms Across Development in Two U.K. Cohorts.
    Am J Psychiatry. 2023;180:755-765.
    PubMed     Abstract available
    
    
    
68. CHATZINAKOS C, Pernia CD, Morrison FG, Iatrou A, et al
    Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
    Am J Psychiatry. 2023;180:739-754.
    PubMed     Abstract available
    
    
    
69. DOCHERTY AR, Mullins N, Ashley-Koch AE, Qin X, et al
    GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
    Am J Psychiatry. 2023;180:723-738.
    PubMed     Abstract available
    
    
    September 2023
70. PINE DS
    Zuranolone Treatment for Depression: Steady Progress in Mechanism-Focused Therapeutics?
    Am J Psychiatry. 2023;180:631-633.
    PubMed    
    
    
    
71. KALIN NH
    Seeking New Solutions Addressing Structural Racism, Childhood Trauma, Suicidal Behaviors Across Sexual Orientations, and Postpartum Depression.
    Am J Psychiatry. 2023;180:625-628.
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72. CLAYTON AH, Lasser R, Parikh SV, Iosifescu DV, et al
    Zuranolone for the Treatment of Adults With Major Depressive Disorder: A Randomized, Placebo-Controlled Phase 3 Trial.
    Am J Psychiatry. 2023;180:676-684.
    PubMed     Abstract available
    
    
    July 2023
73. DELIGIANNIDIS KM, Meltzer-Brody S, Maximos B, Peeper EQ, et al
    Zuranolone for the Treatment of Postpartum Depression.
    Am J Psychiatry. 2023 Jul 26:appiajp20220785. doi: 10.1176/appi.ajp.20220785.
    PubMed     Abstract available
    
    
    
74. JESTER DJ, Kohn JN, Tibirica L, Thomas ML, et al
    Differences in Social Determinants of Health Underlie Racial/Ethnic Disparities in Psychological Health and Well-Being: Study of 11,143 Older Adults.
    Am J Psychiatry. 2023;180:483-494.
    PubMed     Abstract available
    
    
    April 2023
75. BIERNACKA JM
    Do Polygenic Scores Inform Psychiatric Disease Risk After Considering Family History?
    Am J Psychiatry. 2023;180:256-258.
    PubMed    
    
    
    March 2023
76. ELBAU IG, Lynch CJ, Downar J, Vila-Rodriguez F, et al
    Functional Connectivity Mapping for rTMS Target Selection in Depression.
    Am J Psychiatry. 2023;180:230-240.
    PubMed     Abstract available
    
    
    
77. THASE ME
    A New Option for Depressed Patients Who Do Not Respond to Antidepressant Medications.
    Am J Psychiatry. 2023;180:188-189.
    PubMed    
    
    
    
78. KALIN NH
    Insights and Advances Into Treatments for Major Depression.
    Am J Psychiatry. 2023;180:173-176.
    PubMed    
    
    
    
79. JHA MK, Mathew SJ
    Pharmacotherapies for Treatment-Resistant Depression: How Antipsychotics Fit in the Rapidly Evolving Therapeutic Landscape.
    Am J Psychiatry. 2023;180:190-199.
    PubMed     Abstract available
    
    
    
80. NUNES EV
    Alcohol and the Etiology of Depression.
    Am J Psychiatry. 2023;180:179-181.
    PubMed    
    
    
    
81. SACHS GS, Yeung PP, Rekeda L, Khan A, et al
    Adjunctive Cariprazine for the Treatment of Patients With Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study.
    Am J Psychiatry. 2023;180:241-251.
    PubMed     Abstract available
    
    
    
82. DUNLOP BW, Cha J, Choi KS, Rajendra JK, et al
    Shared and Unique Changes in Brain Connectivity Among Depressed Patients After Remission With Pharmacotherapy Versus Psychotherapy.
    Am J Psychiatry. 2023;180:218-229.
    PubMed     Abstract available
    
    
    
83. HASSERIS S, Albinana C, Vilhjalmsson BJ, Mortensen PB, et al
    Polygenic Risk and Episode Polarity Among Individuals With Bipolar Disorder.
    Am J Psychiatry. 2023;180:200-208.
    PubMed     Abstract available
    
    

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