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Articles published in Am J Psychiatry

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Single Articles


    September 2022
  1. LEONE M, Kuja-Halkola R, Leval A, Butwicka A, et al
    Genetic and Environmental Contribution to the Co-Occurrence of Endocrine-Metabolic Disorders and Depression: A Nationwide Swedish Study of Siblings.
    Am J Psychiatry. 2022 Sep 21:appiajp21090954. doi: 10.1176/appi.ajp.21090954.
    PubMed     Abstract available


  2. MARKOWITZ JC, Wright JH, Peeters F, Thase ME, et al
    Psychotherapy's Role for Treatment-Resistant Depression: Reply to Bartova et al.
    Am J Psychiatry. 2022;179:688.
    PubMed    


  3. RICE F
    The Intergenerational Transmission of Anxiety Disorders and Major Depression.
    Am J Psychiatry. 2022;179:596-598.
    PubMed    


  4. DURGAM S, Chen R, Calabrese JR, Sachs GS, et al
    Treatments for Depression in Bipolar II Disorder.
    Am J Psychiatry. 2022;179:688-690.
    PubMed    


  5. BARTOVA L, Fugger G, Dold M, Kautzky A, et al
    Psychotherapy's Role for Treatment-Resistant Depression?
    Am J Psychiatry. 2022;179:687.
    PubMed    


  6. OSTACHER M
    Treatments for Depression in Bipolar II Disorder: Reply to Durgam et al.
    Am J Psychiatry. 2022;179:690.
    PubMed    


  7. KENDLER KS, Abrahamsson L, Ohlsson H, Sundquist J, et al
    An Extended Swedish Adoption Study of Anxiety Disorder and Its Cross-Generational Familial Relationship With Major Depression.
    Am J Psychiatry. 2022;179:640-649.
    PubMed     Abstract available


  8. JAFFE AE, Tao R, Page SC, Maynard KR, et al
    Decoding Shared Versus Divergent Transcriptomic Signatures Across Cortico-Amygdala Circuitry in PTSD and Depressive Disorders.
    Am J Psychiatry. 2022;179:673-686.
    PubMed     Abstract available


    July 2022
  9. HARVEY PD
    Digital Therapeutics to Enhance Cognition in Major Depression: How Can We Make the Cognitive Gains Translate Into Functional Improvements?
    Am J Psychiatry. 2022;179:445-447.
    PubMed    


  10. FERRARELLI F
    Is Neuroplasticity Key to Treatment Response in Depression? Maybe So.
    Am J Psychiatry. 2022;179:451-453.
    PubMed    


  11. PIZZAGALLI DA
    Toward a Better Understanding of the Mechanisms and Pathophysiology of Anhedonia: Are We Ready for Translation?
    Am J Psychiatry. 2022;179:458-469.
    PubMed     Abstract available


  12. TAMM S, Harmer CJ, Schiel J, Holub F, et al
    No Association Between Amygdala Responses to Negative Faces and Depressive Symptoms: Cross-Sectional Data from 28,638 Individuals in the UK Biobank Cohort.
    Am J Psychiatry. 2022;179:509-513.
    PubMed    


  13. KALIN NH
    Neuroscientific Advances Supporting New Treatments for Major Depression.
    Am J Psychiatry. 2022;179:441-444.
    PubMed    


  14. GROGANS SE, Fox AS, Shackman AJ
    The Amygdala and Depression: A Sober Reconsideration.
    Am J Psychiatry. 2022;179:454-457.
    PubMed    


  15. TABUTEAU H, Jones A, Anderson A, Jacobson M, et al
    Effect of AXS-05 (Dextromethorphan-Bupropion) in Major Depressive Disorder: A Randomized Double-Blind Controlled Trial.
    Am J Psychiatry. 2022;179:490-499.
    PubMed     Abstract available


    June 2022
  16. HANKERSON SH, Moise N, Wilson D, Waller BY, et al
    The Intergenerational Impact of Structural Racism and Cumulative Trauma on Depression.
    Am J Psychiatry. 2022;179:434-440.
    PubMed     Abstract available


    May 2022
  17. GE R, Humaira A, Gregory E, Alamian G, et al
    Predictive Value of Acute Neuroplastic Response to rTMS in Treatment Outcome in Depression: A Concurrent TMS-fMRI Trial.
    Am J Psychiatry. 2022 May 18:appiajp21050541. doi: 10.1176/appi.ajp.21050541.
    PubMed     Abstract available


  18. PAN PM, Sato JR, Paillere Martinot ML, Martinot JL, et al
    Longitudinal Trajectory of the Link Between Ventral Striatum and Depression in Adolescence.
    Am J Psychiatry. 2022 May 18:appiajp20081180. doi: 10.1176/appi.ajp.20081180.
    PubMed     Abstract available


    April 2022
  19. KEEFE RSE, Canadas E, Farlow D, Etkin A, et al
    Digital Intervention for Cognitive Deficits in Major Depression: A Randomized Controlled Trial to Assess Efficacy and Safety in Adults.
    Am J Psychiatry. 2022 Apr 12:appiajp21020125. doi: 10.1176/appi.ajp.21020125.
    PubMed     Abstract available


    February 2022
  20. MARKOWITZ JC, Wright JH, Peeters F, Thase ME, et al
    The Neglected Role of Psychotherapy for Treatment-Resistant Depression.
    Am J Psychiatry. 2022;179:90-93.
    PubMed    


  21. WEISSMAN CR, Daskalakis ZJ
    Accelerated Intermittent Theta Burst Stimulation: Expediting and Enhancing Treatment Outcomes in Treatment-Resistant Depression.
    Am J Psychiatry. 2022;179:85-87.
    PubMed    


  22. NEMEROFF CB
    Back to the Future: Esmethadone, the (Maybe) Nonopiate Opiate, and Depression.
    Am J Psychiatry. 2022;179:83-84.
    PubMed    


  23. FAVA M, Stahl S, Pani L, De Martin S, et al
    REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial.
    Am J Psychiatry. 2022;179:122-131.
    PubMed     Abstract available


  24. COLE EJ, Phillips AL, Bentzley BS, Stimpson KH, et al
    Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial.
    Am J Psychiatry. 2022;179:132-141.
    PubMed     Abstract available


    January 2022
  25. KVARTA M, Ma Y, Hong LE
    Comment on "Elevated C-Reactive Protein in Patients With Depression, Independent of Genetic, Health, and Psychosocial Factors: Results From the UK Biobank".
    Am J Psychiatry. 2022;179:73.
    PubMed    


    December 2021
  26. MCINTYRE RS
    Ketamine and Esketamine for Treatment-Resistant Depression: Response to Reus, Mattes, and Schatzberg.
    Am J Psychiatry. 2021;178:1130-1132.
    PubMed    


  27. PARIANTE CM
    Increased Inflammation in Depression: A Little in All, or a Lot in a Few?
    Am J Psychiatry. 2021;178:1077-1079.
    PubMed    


  28. KALIN NH
    New Insights Into Major Depression and the Treatment of Bipolar Depression.
    Am J Psychiatry. 2021;178:1071-1074.
    PubMed    


  29. CONROY SK, Holtzheimer PE
    Neuromodulation Strategies for the Treatment of Depression.
    Am J Psychiatry. 2021;178:1082-1088.
    PubMed     Abstract available


  30. OSTACHER MJ
    Slowly Working Toward More Treatments for Depression in Bipolar II Disorder.
    Am J Psychiatry. 2021;178:1075-1076.
    PubMed    


  31. SCHATZBERG AF
    Mechanisms of Action of Ketamine and Esketamine.
    Am J Psychiatry. 2021;178:1130.
    PubMed    


  32. REUS VI
    Recommendations for the Usage of Ketamine and Esketamine.
    Am J Psychiatry. 2021;178:1129.
    PubMed    


  33. ZHUKOVSKY P, Anderson JAE, Coughlan G, Mulsant BH, et al
    Coordinate-Based Network Mapping of Brain Structure in Major Depressive Disorder in Younger and Older Adults: A Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2021;178:1119-1128.
    PubMed     Abstract available


  34. CALABRESE JR, Durgam S, Satlin A, Vanover KE, et al
    Efficacy and Safety of Lumateperone for Major Depressive Episodes Associated With Bipolar I or Bipolar II Disorder: A Phase 3 Randomized Placebo-Controlled Trial.
    Am J Psychiatry. 2021;178:1098-1106.
    PubMed     Abstract available


    November 2021
  35. KEDING TJ, Heyn SA, Russell JD, Zhu X, et al
    Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology.
    Am J Psychiatry. 2021;178:1026-1036.
    PubMed     Abstract available


    October 2021
  36. FRANK P, Jokela M, Batty GD, Cadar D, et al
    Association Between Systemic Inflammation and Individual Symptoms of Depression: A Pooled Analysis of 15 Population-Based Cohort Studies.
    Am J Psychiatry. 2021 Oct 14:appiajp202120121776.
    PubMed     Abstract available


  37. KALIN NH
    Depression and Schizophrenia: Sleep, Medical Risk Factors, Biomarkers, and Treatment.
    Am J Psychiatry. 2021;178:881-884.
    PubMed    


  38. PLANTE DT
    The Evolving Nexus of Sleep and Depression.
    Am J Psychiatry. 2021;178:896-902.
    PubMed     Abstract available


  39. MCINTYRE RS
    Surrogate Markers of Insulin Resistance in Predicting Major Depressive Disorder: Metabolism Metastasizes to the Brain.
    Am J Psychiatry. 2021;178:885-887.
    PubMed    


  40. WATSON KT, Simard JF, Henderson VW, Nutkiewicz L, et al
    Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study.
    Am J Psychiatry. 2021;178:914-920.
    PubMed     Abstract available


    July 2021
  41. ROXAS N, Ahuja C, Isom J, Wilkinson ST, et al
    A Potential Case of Acute Ketamine Withdrawal: Clinical Implications for the Treatment of Refractory Depression.
    Am J Psychiatry. 2021;178:588-591.
    PubMed    


    June 2021
  42. PENNINX BWJH
    Using the Power of a Giant Wisely: Confirming Inflammation in Depression.
    Am J Psychiatry. 2021;178:480-482.
    PubMed    


  43. KALIN NH
    COVID-19 and Stress-Related Disorders.
    Am J Psychiatry. 2021;178:471-474.
    PubMed    


  44. RUBINOW DR, Lasser R, Kanes SJ
    Comment on "Understanding the Clinical Effects and Mechanisms of Action of Neurosteroids".
    Am J Psychiatry. 2021;178:572-573.
    PubMed    


    May 2021
  45. PITHAROULI MC, Hagenaars SP, Glanville KP, Coleman JRI, et al
    Elevated C-Reactive Protein in Patients With Depression, Independent of Genetic, Health, and Psychosocial Factors: Results From the UK Biobank.
    Am J Psychiatry. 2021 May 14:appiajp202020060947.
    PubMed     Abstract available


  46. MAIXNER DF, Weiner R, Reti IM, Hermida AP, et al
    Electroconvulsive Therapy Is an Essential Procedure.
    Am J Psychiatry. 2021;178:381-382.
    PubMed    


  47. SCHATZBERG AF
    Can Target Engagement Studies Miss Their Targets and Mislead Drug Development?
    Am J Psychiatry. 2021;178:372-374.
    PubMed    


  48. FERRARELLI F, Phillips ML
    Examining and Modulating Neural Circuits in Psychiatric Disorders With Transcranial Magnetic Stimulation and Electroencephalography: Present Practices and Future Developments.
    Am J Psychiatry. 2021;178:400-413.
    PubMed     Abstract available


    April 2021
  49. KALIN NH
    Anxiety, Depression, and Suicide in Youth.
    Am J Psychiatry. 2021;178:275-279.
    PubMed    


  50. PARIKH T, Walkup JT
    The Future of Ketamine in the Treatment of Teen Depression.
    Am J Psychiatry. 2021;178:288-289.
    PubMed    


  51. NEMEROFF CB
    The Trifecta of Misery and Disease Vulnerability: Poverty, Childhood Maltreatment, and Inflammation.
    Am J Psychiatry. 2021;178:282-284.
    PubMed    


  52. BOELEN PA, Lenferink LIM, Spuij M
    CBT for Prolonged Grief in Children and Adolescents: A Randomized Clinical Trial.
    Am J Psychiatry. 2021;178:294-304.
    PubMed     Abstract available


  53. SEQUEIRA SL, Silk JS, Ladouceur CD, Hanson JL, et al
    Association of Neural Reward Circuitry Function With Response to Psychotherapy in Youths With Anxiety Disorders.
    Am J Psychiatry. 2021;178:343-351.
    PubMed     Abstract available


  54. BIERMAN KL, Heinrichs BS, Welsh JA, Nix RL, et al
    Reducing Adolescent Psychopathology in Socioeconomically Disadvantaged Children With a Preschool Intervention: A Randomized Controlled Trial.
    Am J Psychiatry. 2021;178:305-312.
    PubMed     Abstract available


    March 2021
  55. MCINTYRE RS, Rosenblat JD, Nemeroff CB, Sanacora G, et al
    Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
    Am J Psychiatry. 2021 Mar 17:appiajp202020081251.
    PubMed     Abstract available


  56. DWYER JB, Landeros-Weisenberger A, Johnson JA, Londono Tobon A, et al
    Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial.
    Am J Psychiatry. 2021 Mar 3:appiajp202020010018.
    PubMed     Abstract available


  57. COSTI S, Morris LS, Kirkwood KA, Hoch M, et al
    Impact of the KCNQ2/3 Channel Opener Ezogabine on Reward Circuit Activity and Clinical Symptoms in Depression: Results From a Randomized Controlled Trial.
    Am J Psychiatry. 2021 Mar 3:appiajp202020050653.
    PubMed     Abstract available


  58. RUBINOW DR
    One Small Step for PMDD, One Large Step for Affective Disorders.
    Am J Psychiatry. 2021;178:215-217.
    PubMed    


  59. COMASCO E, Kopp Kallner H, Bixo M, Hirschberg AL, et al
    Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial.
    Am J Psychiatry. 2021;178:256-265.
    PubMed     Abstract available


  60. KLEINMAN RA, Schatzberg AF
    Understanding the Clinical Effects and Mechanisms of Action of Neurosteroids.
    Am J Psychiatry. 2021;178:221-223.
    PubMed    


    February 2021
  61. SUMMERS RF, Gorrindo T, Hwang S, Aggarwal R, et al
    Psychiatrist Burnout: Response to Schonfeld and Bianchi.
    Am J Psychiatry. 2021;178:204-205.
    PubMed    


  62. SCHONFELD IS, Bianchi R
    Psychiatrist Burnout.
    Am J Psychiatry. 2021;178:204.
    PubMed    


  63. FEDER A, Costi S, Rutter SB, Collins AB, et al
    A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder.
    Am J Psychiatry. 2021;178:193-202.
    PubMed     Abstract available


    January 2021
  64. SHMULEWITZ D, Aharonovich E, Witkiewitz K, Anton RF, et al
    The World Health Organization Risk Drinking Levels Measure of Alcohol Consumption: Prevalence and Health Correlates in Nationally Representative Surveys of U.S. Adults, 2001-2002 and 2012-2013.
    Am J Psychiatry. 2021 Jan 21:appiajp202020050610.
    PubMed     Abstract available


    November 2020
  65. SINHA R, Wemm S, Fogelman N, Milivojevic V, et al
    Moderation of Prazosin's Efficacy by Alcohol Withdrawal Symptoms.
    Am J Psychiatry. 2020 Nov 19:appiajp202020050609.
    PubMed     Abstract available


    October 2020
  66. COUGHLIN LN, Pfeiffer P, Ganoczy D, Lin LA, et al
    Quality of Outpatient Depression Treatment in Patients With Comorbid Substance Use Disorder.
    Am J Psychiatry. 2020 Oct 29:appiajp202020040454.
    PubMed     Abstract available


  67. MATHEW SJ
    Is Testosterone an Effective Hormonal Therapy for Women With Antidepressant-Resistant Major Depression?
    Am J Psychiatry. 2020;177:891-894.
    PubMed    


  68. KALIN NH
    Insights Into Suicide and Depression.
    Am J Psychiatry. 2020;177:877-880.
    PubMed    


  69. HOLMANS PA
    Using Genetics to Increase Specificity of Outcome Prediction in Psychiatric Disorders: Prospects for Progression.
    Am J Psychiatry. 2020;177:884-887.
    PubMed    


  70. FIRTH J, Wootton RE, Carvalho AF
    Toward Preventive Psychiatry: The Role of Advanced Epidemiological Methods.
    Am J Psychiatry. 2020;177:888-890.
    PubMed    


  71. SUMMERS RF
    The Elephant in the Room: What Burnout Is and What It Is Not.
    Am J Psychiatry. 2020;177:898-899.
    PubMed    


  72. MEDINA-RODRIGUEZ EM, Madorma D, O'Connor G, Mason BL, et al
    Identification of a Signaling Mechanism by Which the Microbiome Regulates Th17 Cell-Mediated Depressive-Like Behaviors in Mice.
    Am J Psychiatry. 2020;177:974-990.
    PubMed     Abstract available


  73. DICHTEL LE, Carpenter LL, Nyer M, Mischoulon D, et al
    Low-Dose Testosterone Augmentation for Antidepressant-Resistant Major Depressive Disorder in Women: An 8-Week Randomized Placebo-Controlled Study.
    Am J Psychiatry. 2020;177:965-973.
    PubMed     Abstract available


    August 2020
  74. MUELLER SC
    Mental Health Treatment Utilization in Transgender Persons: What We Know and What We Don't Know.
    Am J Psychiatry. 2020;177:657-659.
    PubMed    


  75. CARPENTER LL, Philip NS
    The Future Is Now? Rapid Advances by Brain Stimulation Innovation.
    Am J Psychiatry. 2020;177:654-656.
    PubMed    


  76. THASE ME
    Charting Sea Changes in Outpatient Pharmacotherapy of Bipolar Disorder.
    Am J Psychiatry. 2020;177:651-653.
    PubMed    


  77. DWYER JB, Aftab A, Radhakrishnan R, Widge A, et al
    Hormonal Treatments for Major Depressive Disorder: State of the Art.
    Am J Psychiatry. 2020;177:686-705.
    PubMed     Abstract available


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