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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 32 articles:
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Single Articles


    September 2025
  1. MCCARTHY CI, Zack Ma Z, Monteggia LM, Kavalali ET, et al
    Spontaneous glutamate release activates mGluR signaling to drive rapid antidepressant responses.
    Proc Natl Acad Sci U S A. 2025;122:e2510642122.
    PubMed     Abstract available


  2. WANG YH, Fu CL, Chen LB, Zhang CY, et al
    Microglia contribute to bipolar depression through Serinc2-dependent phospholipid synthesis.
    Proc Natl Acad Sci U S A. 2025;122:e2500116122.
    PubMed     Abstract available


  3. LI W, Feng Y, Xu Z, Xu X, et al
    Precise antibody delivery to the brain via nanobubble-actuated focused ultrasound alleviates depression.
    Proc Natl Acad Sci U S A. 2025;122:e2421800122.
    PubMed     Abstract available


    August 2025

  4. Correction for Mellya et al., Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Diceros bicornis michaeli).
    Proc Natl Acad Sci U S A. 2025;122:e2519110122.
    PubMed    


    June 2025
  5. MELLYA RVK, Hopcraft JGC, Mwakilema W, Eblate EM, et al
    Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Diceros bicornis michaeli).
    Proc Natl Acad Sci U S A. 2025;122:e2414412122.
    PubMed     Abstract available


    May 2025
  6. XIA J, Zou Y, Cui Y, Zhang S, et al
    Physical exercise activates a PVN-NAc oxytocin circuit to relieve stress-induced depressive-like behaviors.
    Proc Natl Acad Sci U S A. 2025;122:e2503675122.
    PubMed     Abstract available


    April 2025
  7. MILLER BR, Gonzaga-Jauregui C, Brigatti KW, de Jong J, et al
    A rare variant in GPR156 associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice.
    Proc Natl Acad Sci U S A. 2025;122:e2404754122.
    PubMed     Abstract available


    November 2024
  8. DUARTE Y, Quintana-Donoso D, Moraga-Amaro R, Dinamarca I, et al
    The role of astrocytes in depression, its prevention, and treatment by targeting astroglial gliotransmitter release.
    Proc Natl Acad Sci U S A. 2024;121:e2307953121.
    PubMed     Abstract available


    September 2024
  9. HUR JK, Heffner J, Feng GW, Joormann J, et al
    Language sentiment predicts changes in depressive symptoms.
    Proc Natl Acad Sci U S A. 2024;121:e2321321121.
    PubMed     Abstract available


  10. MARTINEZ M, Cai T, Yang B, Zhou Z, et al
    Depressive symptoms during the transition to adolescence: Left hippocampal volume as a marker of social context sensitivity.
    Proc Natl Acad Sci U S A. 2024;121:e2321965121.
    PubMed     Abstract available


    July 2024
  11. PANDEY S, Han W, Li J, Shepard R, et al
    Reversing anxiety by targeting a stress-responsive signaling pathway.
    Proc Natl Acad Sci U S A. 2024;121:e2400078121.
    PubMed     Abstract available


  12. RAI S, Stade EC, Giorgi S, Francisco A, et al
    Reply to Wang: Clarifying model performance and language markers of depression across races.
    Proc Natl Acad Sci U S A. 2024;121:e2410449121.
    PubMed    


  13. WANG Y
    Large language models for depression prediction.
    Proc Natl Acad Sci U S A. 2024;121:e2409757121.
    PubMed    


  14. PECHEVA D, Smith DM, Casey BJ, Woodward LJ, et al
    Sex and mental health are related to subcortical brain microstructure.
    Proc Natl Acad Sci U S A. 2024;121:e2403212121.
    PubMed     Abstract available


  15. DE FREITAS J
    Do "Black individuals" really display no linguistic markers of depression?
    Proc Natl Acad Sci U S A. 2024;121:e2410997121.
    PubMed    


  16. RAI S, Stade EC, Giorgi S, Francisco A, et al
    Reply to De Freitas: Social media language explains less of the variance in depression of Black individuals than of White individuals.
    Proc Natl Acad Sci U S A. 2024;121:e2411458121.
    PubMed    


    May 2024
  17. JI S, Guo Y, Yan W, Wei F, et al
    PM(2.5) exposure contributes to anxiety and depression-like behaviors via phenyl-containing compounds interfering with dopamine receptor.
    Proc Natl Acad Sci U S A. 2024;121:e2319595121.
    PubMed     Abstract available


  18. KNIGHT DJ, Zhang B
    Residential mobility and persistently depressed voting among disadvantaged adults in a large housing experiment.
    Proc Natl Acad Sci U S A. 2024;121:e2306287121.
    PubMed     Abstract available


  19. LAVANCHY E, Weir BS, Goudet J
    Detecting inbreeding depression in structured populations.
    Proc Natl Acad Sci U S A. 2024;121:e2315780121.
    PubMed     Abstract available


    April 2024
  20. KUNG CSJ, Steptoe A
    Changes in well-being among socially isolated older people during the COVID-19 pandemic: An outcome-wide analysis.
    Proc Natl Acad Sci U S A. 2024;121:e2308697121.
    PubMed     Abstract available


  21. RAI S, Stade EC, Giorgi S, Francisco A, et al
    Key language markers of depression on social media depend on race.
    Proc Natl Acad Sci U S A. 2024;121:e2319837121.
    PubMed     Abstract available


    December 2023
  22. AKIL H, Nestler EJ
    The neurobiology of stress: Vulnerability, resilience, and major depression.
    Proc Natl Acad Sci U S A. 2023;120:e2312662120.
    PubMed    


  23. SHIMO Y, Cathomas F, Lin HY, Chan KL, et al
    Social stress induces autoimmune responses against the brain.
    Proc Natl Acad Sci U S A. 2023;120:e2305778120.
    PubMed     Abstract available


  24. PAREL ST, Bennett SN, Cheng CJ, Timmermans OC, et al
    Transcriptional signatures of early-life stress and antidepressant treatment efficacy.
    Proc Natl Acad Sci U S A. 2023;120:e2305776120.
    PubMed     Abstract available


  25. KRYSTAL JH, Kaye AP, Jefferson S, Girgenti MJ, et al
    Ketamine and the neurobiology of depression: Toward next-generation rapid-acting antidepressant treatments.
    Proc Natl Acad Sci U S A. 2023;120:e2305772120.
    PubMed     Abstract available


  26. TURNER CA, Khalil H, Murphy-Weinberg V, Hagenauer MH, et al
    The impact of COVID-19 on a college freshman sample reveals genetic and nongenetic forms of susceptibility and resilience to stress.
    Proc Natl Acad Sci U S A. 2023;120:e2305779120.
    PubMed     Abstract available


    November 2023
  27. KELLEY SW, Fisher AJ, Lee CT, Gallagher E, et al
    Elevated emotion network connectivity is associated with fluctuations in depression.
    Proc Natl Acad Sci U S A. 2023;120:e2216499120.
    PubMed     Abstract available


    October 2023
  28. SEPAHVAND T, Nazari N, Qin T, Rajani V, et al
    Olfactory threat extinction in the piriform cortex: An age-dependent employment of NMDA receptor-dependent long-term depression.
    Proc Natl Acad Sci U S A. 2023;120:e2309986120.
    PubMed     Abstract available


    June 2023
  29. CHAI Y, Gehrman P, Yu M, Mao T, et al
    Enhanced amygdala-cingulate connectivity associates with better mood in both healthy and depressive individuals after sleep deprivation.
    Proc Natl Acad Sci U S A. 2023;120:e2214505120.
    PubMed     Abstract available


    May 2023
  30. MITRA A, Raichle ME, Geoly AD, Kratter IH, et al
    Targeted neurostimulation reverses a spatiotemporal biomarker of treatment-resistant depression.
    Proc Natl Acad Sci U S A. 2023;120:e2218958120.
    PubMed     Abstract available


  31. WANG A, Wan X, Zhuang P, Jia W, et al
    High fried food consumption impacts anxiety and depression due to lipid metabolism disturbance and neuroinflammation.
    Proc Natl Acad Sci U S A. 2023;120:e2221097120.
    PubMed     Abstract available


    April 2023
  32. HAO Y, Farah MJ
    Heterogeneity of depression across the socioeconomic spectrum.
    Proc Natl Acad Sci U S A. 2023;120:e2222069120.
    PubMed     Abstract available


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