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  Diabetes

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06.10.2025

2 Am J Cardiol
4 Am J Clin Nutr
2 Biochem Biophys Res Commun
2 BMC Ophthalmol
2 BMC Pediatr
3 BMJ
3 Diabet Med
1 Diabetes
4 Diabetes Care
6 Diabetes Obes Metab
7 Diabetologia
2 Invest Ophthalmol Vis Sci
1 J Am Soc Nephrol
1 J Biol Chem
3 J Clin Endocrinol Metab
3 J Clin Invest
2 J Diabetes Complications
1 J Immunol
2 Metabolism
1 Ophthalmol Retina
1 Pediatr Diabetes
1 PLoS Genet
12 PLoS One


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Cardiol

  1. SHUJA SH, Shuja MH, Shaukat A, Hannat R, et al
    GLP-1 Receptor Agonists and Cardiovascular Outcomes in Adults with Diabetes and Peripheral Artery Disease: An Updated Systematic Review and Meta-Analysis.
    Am J Cardiol. 2025 Sep 27:S0002-9149(25)00595.
    PubMed         Abstract available

  2. AL-HOLY A, Comanici M, Das A, Marczin N, et al
    Single Arterial versus Multiple Arterial Grafting in 3,164 Diabetic Patients Undergoing Coronary Artery Bypass Surgery: A Propensity-Matched Analysis.
    Am J Cardiol. 2025 Sep 22:S0002-9149(25)00572.
    PubMed         Abstract available


    Am J Clin Nutr

  3. BODNAR LM, Kirkpatrick SI, Yu YH, Kennedy E, et al
    Heterogeneity in the association between a dietary pattern high in fat, sugar, and sodium and adverse pregnancy outcomes by maternal characteristics: a US pregnancy cohort study.
    Am J Clin Nutr. 2025 Jul 11:S0002-9165(25)00394.
    PubMed         Abstract available

  4. HENDERSON GC
    The regulation of fatty acid mobilization is extravagant rather than frugal: a perspective indicating a limitation of the thrifty genotype hypothesis.
    Am J Clin Nutr. 2025;122:913-922.
    PubMed         Abstract available

  5. ELLISON KM, El Zein A, Baidwan NK, Ferguson CC, et al
    Adaptive Dietary and exercise strategies for weight loss in Adults with Prediabetes Trial (ADAPT): A Sequential Multiple Assignment Randomized Trial.
    Am J Clin Nutr. 2025 Aug 3:S0002-9165(25)00451.
    PubMed         Abstract available

  6. MODOC DP, Ahmed S, Chisenga M, Cox SE, et al
    Associations of prior wasting malnutrition with later indicators of glucose tolerance across four countries in Africa and Asia: the SAMPA cohort study.
    Am J Clin Nutr. 2025 Aug 4:S0002-9165(25)00449.
    PubMed         Abstract available


    Biochem Biophys Res Commun

  7. ZHAO S, Zhang Y, Li C, Zheng Z, et al
    Succinate-mediated Ufsp2 transcription promotes high glucose-stimulated pyroptosis in rat retinal Muller cells by activating NLRP3 inflammasome.
    Biochem Biophys Res Commun. 2025;783:152614.
    PubMed         Abstract available

  8. WANG Q, Zhang P, Ji F, Li Y, et al
    Stigmasterol improves diabetic retinopathy by inhibiting VAMP7-mediated autophagy/mitophagy.
    Biochem Biophys Res Commun. 2025;785:152653.
    PubMed         Abstract available


    BMC Ophthalmol

  9. CAO Y, Wang B, Li M, Sun A, et al
    Outcome of silicone oil tamponade combined dexamethasone implantation in patients with proliferative diabetic retinopathy and retinal detachment undergoing vitrectomy: a prospective randomized controlled clinical trial.
    BMC Ophthalmol. 2025;25:523.
    PubMed         Abstract available

  10. SAKALLIOGLU AK, Engi?n T, Bek T, Guclu H, et al
    Analgesic efficacy of 7 different topical NSAIDs in panretinal photocoagulation-associated pain.
    BMC Ophthalmol. 2025;25:539.
    PubMed         Abstract available


    BMC Pediatr

  11. SPURR S, M G Bally J, Burles M, Langdon C, et al
    Examining conceptions of hope to inform development of strength-based activities to prevent type 2 diabetes among Indigenous youth.
    BMC Pediatr. 2025;25:686.
    PubMed         Abstract available

  12. LIU X, Peng Z, Ma S, Liu F, et al
    Value of elevated 1-hour post-load plasma glucose level in identifying risk of MAFLD in non-diabetic obese children and adolescents.
    BMC Pediatr. 2025;25:700.
    PubMed         Abstract available


    BMJ

  13. TAYLOR L
    Sixty seconds on . . . type 5 diabetes.
    BMJ. 2025;391:r2092.
    PubMed        

  14. MCCRAY BA, Stino AM, Davalos L, Quigley S, et al
    Atypical diabetic neuropathies.
    BMJ. 2025;390:e081109.
    PubMed         Abstract available

  15. FARMER A, Patel K, Dambha-Miller H
    Once weekly insulin in type 2 diabetes.
    BMJ. 2025;390:r1931.
    PubMed        


    Diabet Med

  16. WINSTON AP, Eriksson A
    Disordered eating and type 2 diabetes: The case for T2DE.
    Diabet Med. 2025 Oct 3:e70150. doi: 10.1111/dme.70150.
    PubMed        

  17. JESPERSEN LN, Schonning SH, Truelsen MF, Grabowski D, et al
    Facilitating dialogue with adolescents with diabetes: Development of 'The Adolescent Mirror'-A research-based dialogue tool.
    Diabet Med. 2025 Oct 3:e70144. doi: 10.1111/dme.70144.
    PubMed         Abstract available

  18. THOMAS JJC, Lanzinger S, Soerensen KK, Imberg H, et al
    A cohort description and comparison of four European national diabetes registries for the REDDIE project.
    Diabet Med. 2025 Oct 1:e70112. doi: 10.1111/dme.70112.
    PubMed         Abstract available


    Diabetes

  19. WANG X, Wan J, Wang C, Tong Y, et al
    Trem2+ Macrophages Alleviate Renal Tubule Lipid Accumulation and Ferroptosis in Diabetic Nephropathy by Repressing IL-1beta-Mediated CD36 Expression.
    Diabetes. 2025 Oct 3:db250282. doi: 10.2337/db25-0282.
    PubMed         Abstract available


    Diabetes Care

  20. WINN AN, Newman Z, Deckard A, Franco-Galicia MI, et al
    Development and Internal Validation of the Multiethnic Type 2 Diabetes Outcomes Model for the U.S. (DOMUS).
    Diabetes Care. 2025 Sep 25:dc250911. doi: 10.2337/dc25-0911.
    PubMed         Abstract available

  21. MARTIN S, Samuel M, Stow D, Ridsdale AM, et al
    Undiagnosed G6PD Deficiency in Black and Asian Individuals Is Prevalent and Contributes to Health Inequalities in Type 2 Diabetes Diagnosis and Complications.
    Diabetes Care. 2025 Sep 30:dc250556. doi: 10.2337/dc25-0556.
    PubMed         Abstract available

  22. LIU B, Wang Y, Hu Y, Wan Y, et al
    Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies.
    Diabetes Care. 2025 Sep 30:dc251401. doi: 10.2337/dc25-1401.
    PubMed         Abstract available

  23. SHU X, Juan J, Yao M, Li C, et al
    Glycemic Level Modifies the Relationship Between Maternal Gestational Weight Gain and Neonatal Birth Weight in Type 2 Diabetes-Complicated Pregnancies.
    Diabetes Care. 2025 Oct 1:dc251086. doi: 10.2337/dc25-1086.
    PubMed         Abstract available


    Diabetes Obes Metab

  24. PAN Y, Zhang W, Dai Y, Liu Y, et al
    Association between accelerometer-measured physical activity, genetic risk, and incident type 2 diabetes: A prospective cohort study.
    Diabetes Obes Metab. 2025 Oct 3. doi: 10.1111/dom.70166.
    PubMed         Abstract available

  25. DI MOLFETTA S, Di Gioia L, Caruso I, Caporusso M, et al
    Glycaemic control and variability with different commercially available hybrid closed loop systems in people with type 1 diabetes: A systematic review and meta-analysis of randomized controlled trials.
    Diabetes Obes Metab. 2025 Sep 29. doi: 10.1111/dom.70150.
    PubMed         Abstract available

  26. CHANG Y, Hsieh MH, Ju PC, Chang CC, et al
    Risk of depression with GLP-1 receptor agonists use in overweight or obese adults with type 2 diabetes: A new-user, active-comparator cohort study.
    Diabetes Obes Metab. 2025 Sep 29. doi: 10.1111/dom.70175.
    PubMed         Abstract available

  27. CHEN MH, Lin LY, Hung TY, Lin TC, et al
    Comparative cardiovascular risk of sulfonylureas with low- and high-affinities for cardiac mitochondrial adenosine triphosphate-sensitive potassium channels versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes: A cohort study.
    Diabetes Obes Metab. 2025 Sep 29. doi: 10.1111/dom.70157.
    PubMed         Abstract available

  28. ZHOU Z, Gao N, Liu J, Ma X, et al
    An interpretable machine learning model for predicting metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes.
    Diabetes Obes Metab. 2025 Sep 29. doi: 10.1111/dom.70168.
    PubMed         Abstract available

  29. HANKOSKY ER, Lebrec J, Lee CJ, Dimitriadis GK, et al
    Tirzepatide and the 10-year predicted risk of cardiovascular disease and type 2 diabetes in adults with obesity and prediabetes: A post hoc analysis from the three-year SURMOUNT-1 trial.
    Diabetes Obes Metab. 2025 Sep 29. doi: 10.1111/dom.70143.
    PubMed         Abstract available


    Diabetologia

  30. ZHAO LP, Papadopoulos GK, McFarland BJ, Skyler JS, et al
    Correction: Profiling associations of interactive ligand-receptors (HLA class I and KIR gene products) with the progression to type 1 diabetes among seroconverted participants.
    Diabetologia. 2025 Sep 27. doi: 10.1007/s00125-025-06557.
    PubMed        

  31. CASTELBLANCO E, Shyr ZA, Ramirez-Sotero I, Yan Z, et al
    Restoration of pancreatic beta cell identity and autophagy in K(ATP)-induced diabetes by intermittent fasting.
    Diabetologia. 2025 Sep 25. doi: 10.1007/s00125-025-06545.
    PubMed         Abstract available

  32. TRIMBLE ER, Phillips DIW, Balcha SA
    Phenotype of insulin-dependent diabetes in chronic undernutrition: beta cell stress and immune dysfunction-a rural sub-Saharan perspective on type 5 diabetes.
    Diabetologia. 2025 Sep 29. doi: 10.1007/s00125-025-06553.
    PubMed         Abstract available

  33. ALBARGOTHY MJ, Troendle EP, Laws R, Barabas P, et al
    3D electron microscopy reveals novel ultrastructural changes in the diabetic retinal neurovascular unit.
    Diabetologia. 2025 Oct 2. doi: 10.1007/s00125-025-06554.
    PubMed         Abstract available

  34. PAPADIMOS ER, Claussen C, Magliano DJ, Hotu C, et al
    Prevalence of youth type 2 diabetes in global Indigenous populations: a systematic review.
    Diabetologia. 2025 Oct 2. doi: 10.1007/s00125-025-06556.
    PubMed         Abstract available

  35. MICHALEK DA, Tern C, Robertson CC, Chen WM, et al
    HLA-focused type 1 diabetes genetic risk prediction in populations of diverse ancestry.
    Diabetologia. 2025 Oct 2. doi: 10.1007/s00125-025-06563.
    PubMed         Abstract available

  36. ZHANG Y, Giovannucci EL, Wang DD
    Methodological considerations for interpreting long-term statin use and diabetes incidence. Reply to Ma C, Zeng H [letter].
    Diabetologia. 2025 Oct 3. doi: 10.1007/s00125-025-06569.
    PubMed        


    Invest Ophthalmol Vis Sci


  37. Erratum in: Comments on "Real-World Outcomes After Switch From Aflibercept to Faricimab in Eyes With Diabetic Macular Edema".
    Invest Ophthalmol Vis Sci. 2025;66:64.
    PubMed        

  38. WANG N, Yao F, Xu W, Feng T, et al
    The Transcription Factor Islet-1 Regulates Diabetes-Induced Inner Blood-Retinal Barrier Disruption.
    Invest Ophthalmol Vis Sci. 2025;66:8.
    PubMed         Abstract available


    J Am Soc Nephrol

  39. RHEE CM, Allon M, Mehrotra R
    Commemorating the National Institute of Diabetes and Digestive and Kidney Diseases' Advances in Kidney Health: 75 Years of Discovery and Impact.
    J Am Soc Nephrol. 2025 Sep 30. doi: 10.1681/ASN.0000000898.
    PubMed         Abstract available


    J Biol Chem

  40. GU J, Qi MX, Zhang RX, Song YY, et al
    Sidt2 inhibits islet beta-cell dedifferentiation by regulating insulin secretion.
    J Biol Chem. 2025;301:110544.
    PubMed         Abstract available


    J Clin Endocrinol Metab

  41. HOLLIDAY MW JR, Navaneethan SD
    Impact of SGLT2 inhibitors on glomerular filtration in type 1 diabetes.
    J Clin Endocrinol Metab. 2025 Sep 25:dgaf535. doi: 10.1210.
    PubMed        

  42. SCHILLER T, Gabay L, Barak O, Kirzhner A, et al
    An oral glucose tolerance test in pregnancy can serve as a valuable predictor for future diabetes.
    J Clin Endocrinol Metab. 2025 Sep 26:dgaf534. doi: 10.1210.
    PubMed         Abstract available

  43. DENSON AM, Rodriguez KE, Letourneau-Freiberg LR, Kandasamy B, et al
    Children with Pancreatic Hypoplasia Experience Poor Weight Gain and Labile Diabetes but Low Incidence of DKA.
    J Clin Endocrinol Metab. 2025 Sep 27:dgaf473. doi: 10.1210.
    PubMed         Abstract available


    J Clin Invest

  44. DOS SANTOS T, Dai XQ, Jones RC, Spigelman AF, et al
    Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes.
    J Clin Invest. 2025 Sep 30:e195267. doi: 10.1172/JCI195267.
    PubMed         Abstract available

  45. SASSI G, Lemaitre P, Fernandez Calvo L, Lodi F, et al
    Neutrophil-enriched gene signature correlates with teplizumab therapy resistance in different stages of type 1 diabetes.
    J Clin Invest. 2025 Sep 30:e176403. doi: 10.1172/JCI176403.
    PubMed         Abstract available

  46. KATZ LS, Scott DK, Stewart AF
    SIRT2 puts the brakes on human beta cell proliferation: therapeutic opportunities and next challenges.
    J Clin Invest. 2025;135:e197142.
    PubMed         Abstract available


    J Diabetes Complications

  47. HOFFMANN K, Paczkowska A, Maggio V, Rizzo M, et al
    The cardiovascular-kidney-metabolic staging in type 2 diabetes: the clock starts ticking early.
    J Diabetes Complications. 2025;39:109177.
    PubMed         Abstract available

  48. CHEN KY, Chan HC, Chan CM
    Can fibrate therapy redefine the management of diabetic retinopathy? A comprehensive systematic review and meta-analysis of efficacy and safety.
    J Diabetes Complications. 2025;39:109178.
    PubMed         Abstract available


    J Immunol

  49. PAFLIOTI E, Kandylaki E, Sperelakis I, Kontakis G, et al
    Diabetes and insulin resistance alters ligamentum flavum-derived fibroblast responses in an AKT2-dependent manner.
    J Immunol. 2025 Oct 3:vkaf233. doi: 10.1093.
    PubMed         Abstract available


    Metabolism

  50. MISHRA RC, Mallat RK, John CM, Belke D, et al
    Administration of the K(Ca) channel activator SKA-31 improves long-term endothelial function, blood pressure regulation and cardiac performance in rats with type 2 diabetes.
    Metabolism. 2025 Oct 1:156410. doi: 10.1016/j.metabol.2025.156410.
    PubMed         Abstract available

  51. YANG J, Yang X, Zheng Y, Wang A, et al
    27-Hydroxycholesterol exacerbates hepatic insulin resistance via plasma membrane cholesterol remodeling.
    Metabolism. 2025;173:156392.
    PubMed         Abstract available


    Ophthalmol Retina

  52. MARQUES-COUTO P, Afonso J, Coelho-Costa I, Neves JS, et al
    Prevalence and Risk Factors of Diabetic Macular Edema in Type 1 Diabetes: A Systematic Review and Meta-Analysis.
    Ophthalmol Retina. 2025 Sep 26:S2468-6530(25)00433.
    PubMed         Abstract available


    Pediatr Diabetes

  53. YOU L, Salami F, Tamura R, Torn C, et al
    Predictors of Transitions From GADA as the Initial Autoantibody to Multiple Autoantibodies of Type 1 Diabetes in Children at Risk by a Dynamic Prediction Model.
    Pediatr Diabetes. 2025;2025:8845330.
    PubMed         Abstract available


    PLoS Genet

  54. WILHELM K, Asmussen J, Lee K, Samieinasab M, et al
    Meta-evolutionary exome analysis identifies novel type 2 diabetes mellitus genes in the UK Biobank and all of us.
    PLoS Genet. 2025;21:e1011889.
    PubMed         Abstract available


    PLoS One

  55. NAKHOUL L, Nakhoul T, Abi Azar M, Harb F, et al
    The efficacy of DPP IV inhibitors as adjunct therapy for patients with auto-immune Diabetes: A systematic review and meta-analysis.
    PLoS One. 2025;20:e0332191.
    PubMed         Abstract available

  56. FARNOOSH R, Abnoosian K, Isewid RA, Javaheri D, et al
    DiabetesXpertNet: An innovative attention-based CNN for accurate type 2 diabetes prediction.
    PLoS One. 2025;20:e0330454.
    PubMed         Abstract available

  57. MERSHA AB, Shimekaw A, Gebremedhin E, Sewalem J, et al
    Diabetes-related distress and associated factors among adult diabetes mellitus patients attending public hospitals in Gedio zone, southern Ethiopia: Mediation analysis.
    PLoS One. 2025;20:e0331655.
    PubMed         Abstract available

  58. YANG Y, Liu H
    The association of different types of physical activity and diabetes co-morbid depression: A cross-sectional analysis.
    PLoS One. 2025;20:e0332719.
    PubMed         Abstract available

  59. RHMARI TLEMCANI FZ, Aitlahbib F, Laidi S, Alidrissi N, et al
    Diabetic retinopathy as the primary predictor of mild cognitive impairment in type 2 diabetes: Insights from machine learning models.
    PLoS One. 2025;20:e0332442.
    PubMed         Abstract available

  60. MI W, Wang C
    Role of weight-adjusted waist circumference index and non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio in prediabetes risk: A mediation analysis.
    PLoS One. 2025;20:e0331866.
    PubMed         Abstract available

  61. REHMAN S, Ishtiaq S, Hafeez Kamran S, Khalil-Ur-Rehman M, et al
    Investigation of phytochemical and biochemical attributes of hypoglycemic activity of Atriplex crassifolia (C.A. Mey) extracts in alloxan diabetic animal model.
    PLoS One. 2025;20:e0333425.
    PubMed         Abstract available

  62. MOHAMMADI S, Khorami B, Seyedtabib M, Najafpour Z, et al
    Determinants of medication adherence among older adults with type 2 diabetes using the health action process approach: A cross-sectional study.
    PLoS One. 2025;20:e0332235.
    PubMed         Abstract available

  63. SAMAMI M, Valaei-Barhagh A, Joukar F, Hassanipour S, et al
    Diabetes and oral health: A comparative cross-sectional analysis of DMFT index among diabetic, pre-diabetic, and non-diabetic adults.
    PLoS One. 2025;20:e0331775.
    PubMed         Abstract available

  64. WIDATALLA N, Al Younis S, Ghosh SK, Khandoker A, et al
    Symbolic heart rate transition motifs during nocturnal sleep are associated with diabetic complications in type 2 diabetes.
    PLoS One. 2025;20:e0333067.
    PubMed         Abstract available

  65. MAHMOUDI R, Nabaee M, Kooshki A, Yazdi SS, et al
    Prebiotic food intake and biochemical measures in diabetic patients: A cross-sectional study from the Sabzevar Persian Cohort.
    PLoS One. 2025;20:e0332029.
    PubMed         Abstract available

  66. GOUGH A, Marshall T, Sitch A
    Within-individual variation of HbA1c measurements in primary care: A retrospective cohort study.
    PLoS One. 2025;20:e0333438.
    PubMed         Abstract available


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