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5 Am J Clin Nutr |
Retrieve available abstracts of this week’s articles:
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Cross-sectional analysis of visceral adipose tissue associations with
obesity-related disease.
Am J Clin Nutr. 2025;122:1489-1497.
PubMed
Abstract available
Novel protein targets for type 2 diabetes prevention and their mediating role in
the diet-disease relationship: evidence from 2 population-based cohorts and a
Mendelian randomization analysis.
Am J Clin Nutr. 2025;122:1400-1412.
PubMed
Abstract available
Proteins and the crossroads of diet and type 2 diabetes.
Am J Clin Nutr. 2025;122:1143-1144.
PubMed
The effect of muscle quality index on risk of adverse health outcomes: a
prospective cohort study of 355,209 adults.
Am J Clin Nutr. 2025;122:1452-1460.
PubMed
Abstract available
A scoping review on the possible immunometabolic properties of the furan fatty
acid metabolite 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid.
Am J Clin Nutr. 2025;122:1155-1160.
PubMed
Abstract available
Endothelin-1 and cardio-kidney events among patients with CKD, diabetes, and
anemia.
Am J Nephrol. 2025 Nov 3:1-19. doi: 10.1159/000549255.
PubMed
Abstract available
Association of Liver Fat Content With Carotid Endothelial Function in Patients
With Newly Diagnosed Type 2 Diabetes Mellitus and Pre-Diabetes Mellitus.
Angiology. 2025 Nov 6:33197251384344. doi: 10.1177/00033197251384344.
PubMed
Abstract available
In adults with obesity but without type 2 diabetes, tirzepatide increased weight
loss at 72 wk compared with semaglutide.
Ann Intern Med. 2025 Nov 4. doi: 10.7326/ANNALS-25-04321.
PubMed
Abstract available
Comparative Gastrointestinal Safety of Dulaglutide, Semaglutide, and Tirzepatide
in Adults With Type 2 Diabetes.
Ann Intern Med. 2025 Nov 4. doi: 10.7326/ANNALS-25-01724.
PubMed
Abstract available
Ornithine decarboxylase 1 modulation regulates plasma membrane integrity and
associated gene networks under glucotoxicity and lipotoxicity stress: An in vitro
study.
Biochem Biophys Res Commun. 2025;788:152807.
PubMed
Abstract available
Tirzepatide improves extracellular matrix integrity and vascularization in
pancreatic islets of a mouse model of obesity, diabetes, and menopause.
Biochem Biophys Res Commun. 2025;790:152913.
PubMed
Abstract available
PKA-mediated Drp1 Ser637 phosphorylation modulates mitochondrial function in the
placenta of gestational diabetes mellitus.
Biochem Biophys Res Commun. 2025;790:152919.
PubMed
Abstract available
The effects of L-tartaric acid on diabetic cataracts through modulation of
oxidative stress and inflammation in diabetic rats.
BMC Ophthalmol. 2025;25:615.
PubMed
Abstract available
Towards better Diabetes Data Rights: Data protection, data 'ownership', and
developing a patient charter.
Diabet Med. 2025 Nov 6:e70160. doi: 10.1111/dme.70160.
PubMed
Abstract available
Physical activity (20 min) is a powerful adjunct to insulin for correcting
hyperglycaemia in Type 1 diabetes: A paradigm shift.
Diabet Med. 2025 Nov 5:e70163. doi: 10.1111/dme.70163.
PubMed
Flt3L-Derived Antigen-Presenting Cell Transfer in Neonatal NOD Mice Reduces the
Incidence of Type 1 Diabetes.
Diabetes. 2025 Nov 6:db250055. doi: 10.2337/db25-0055.
PubMed
Abstract available
Lysyl Oxidase Promotes Actin-Dependent Neutrophil Activation and Cytotoxicity
Toward Retinal Endothelial Cells in Diabetes.
Diabetes. 2025 Nov 4:db250541. doi: 10.2337/db25-0541.
PubMed
Abstract available
Association of the Age at Type 2 Diabetes Onset With Diabetes Progression.
Diabetes Care. 2025 Nov 7:dc251811. doi: 10.2337/dc25-1811.
PubMed
Abstract available
Hypoglycemia Beliefs, Impaired Hypoglycemia Awareness, and Severe Hypoglycemia in
Insulin-Treated Type 2 Diabetes: Insights From CGM Users.
Diabetes Care. 2025 Nov 6:dc251778. doi: 10.2337/dc25-1778.
PubMed
Toward Disease-Modifying Therapies in Type 1 Diabetes: Focus on Teplizumab.
Diabetes Care. 2025 Nov 6:dci250066. doi: 10.2337/dci25-0066.
PubMed
Abstract available
Changes in Type 2 Diabetes Medications Among Primary Care Patients After
California's 2022 Medicaid Expansion.
Diabetes Care. 2025 Nov 5:dc250787. doi: 10.2337/dc25-0787.
PubMed
Abstract available
Discrepancies between current displayed and auto-logged glucose values in
FreeStyle Libre 3: Implications for clinical interpretation.
Diabetes Obes Metab. 2025;27:7367-7373.
PubMed
Abstract available
Diabetic distal symmetric polyneuropathy: More than just "tingling in the feet".
Diabetes Obes Metab. 2025 Nov 6. doi: 10.1111/dom.70235.
PubMed
Abstract available
Associations between gestational diabetes and cardiovascular disease largely
operate independently of postpartum causal pathways: A population-based cohort
study in England.
Diabetes Obes Metab. 2025 Nov 5. doi: 10.1111/dom.70210.
PubMed
Abstract available
Coated glucose microbeads stimulate enteric hormone release and improve glucose
tolerance in Phase 1 and 2 clinical trials.
Diabetes Obes Metab. 2025;27:7344-7354.
PubMed
Abstract available
Deletion of RalGAPbeta protects pancreatic beta cells and improves glycemic control.
Diabetes Obes Metab. 2025;27:7323-7343.
PubMed
Abstract available
A review of multidisciplinary care in metabolic dysfunction-associated
steatohepatitis and cardiometabolic disease, with a focus on Canada.
Diabetes Obes Metab. 2025;27:6831-6846.
PubMed
Abstract available
Sex differences in the efficacy of GLP-1 receptor agonists: A systematic review
and meta-analysis of cardiovascular and renal outcome trials.
Diabetes Obes Metab. 2025;27:6847-6856.
PubMed
Abstract available
Efficacy and safety of survodutide on glycemic control and weight loss in adults:
A systematic review and meta-analysis.
Diabetes Obes Metab. 2025;27:7062-7074.
PubMed
Abstract available
Acute inflammation amplifies the diabetogenic effect of excess adiposity:
Evidence from a real-life, prospective cohort.
Diabetes Obes Metab. 2025 Nov 5. doi: 10.1111/dom.70274.
PubMed
Abstract available
Efficacy and safety of switching to ezetimibe 10 mg/rosuvastatin 2.5 mg in Korean
patients with type 2 diabetes mellitus and dyslipidaemia: A multicentre,
prospective study (EROICA study).
Diabetes Obes Metab. 2025 Nov 5. doi: 10.1111/dom.70258.
PubMed
Abstract available
Safety and efficacy of hybrid closed-loop insulin pump therapy in adolescents and
adults with type 1 diabetes in China.
Diabetes Obes Metab. 2025 Nov 5. doi: 10.1111/dom.70227.
PubMed
Abstract available
One-year usage patterns of SGLT-2 inhibitors and GLP-1 receptor agonists in
individuals with type 2 diabetes in a real-world population.
Diabetes Obes Metab. 2025 Nov 4. doi: 10.1111/dom.70269.
PubMed
Abstract available
Availability and readiness of health facilities for chronic kidney disease,
diabetes and cardiovascular disease in Ethiopia: Evidence from service provision
assessment data.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70268.
PubMed
Abstract available
Real-world incidence and risk factors of level 3 (severe) hypoglycaemia in adults
with type 1 or 2 diabetes (iNPHORM, United States).
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70252.
PubMed
Abstract available
Cardiorespiratory fitness and type 2 diabetes risk: A prospective cohort study
with mediation analysis of biological aging in the UK Biobank.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70261.
PubMed
Abstract available
Pharmacological intervention: Challenges and promising outcomes for fat loss and
preservation of lean body mass in the treatment of overweight and type 2
diabetes.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70229.
PubMed
Abstract available
Importance of targeting post-prandial hyperglycaemia to achieve HbA1c goals in
insulin glargine-treated subphenotypes of type 2 diabetes.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70231.
PubMed
Abstract available
Progressive increases in adiposity and ectopic fat surrogates across glycaemic
states highlight weight reduction as a key target for type 2 diabetes prevention,
especially in younger people.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70248.
PubMed
Abstract available
GlucoNet-MM: A multimodal attention-based multi-task learning framework with
decision transformer for personalised and explainable blood glucose forecasting.
Diabetes Obes Metab. 2025;27:7416-7430.
PubMed
Abstract available
Efficacy and safety of Efsubaglutide Alfa in "overrun" patients in the SUPER2
trial: A post-hoc analysis for comprehensive evaluation.
Diabetes Obes Metab. 2025;27:7123-7132.
PubMed
Abstract available
Genetic evidence for repurposing GLP-1 receptor agonists in chronic kidney
disease and IgA nephropathy: Metabolic and anti-inflammatory pathways beyond
glycaemic control.
Diabetes Obes Metab. 2025;27:7395-7407.
PubMed
Abstract available
Boosting the engraftment of subcutaneously transplanted pancreatic islets by
nanofat.
Diabetes Obes Metab. 2025;27:7258-7274.
PubMed
Abstract available
Shared mechanistic pathways of glucagon signalling: Unlocking its potential for
treating obesity, metabolic dysfunction-associated steatotic liver disease, and
other cardio-kidney-metabolic conditions.
Diabetes Obes Metab. 2025;27:6869-6883.
PubMed
Abstract available
Contributions of intermittently scanned continuous glucose monitoring frequency
and bolus insulin dosing on time in range: Analysis of data from CGM and
connected insulin pens.
Diabetes Obes Metab. 2025;27:7570-7577.
PubMed
Abstract available
Addressing the risk of ocular complications of GLP-1RAs; a multi-disciplinary
expert consensus.
Diabetes Obes Metab. 2025;27:7535-7543.
PubMed
Abstract available
Two-tier screening approach for liver fibrosis stratification in outpatients with
type 2 diabetes mellitus: A multicenter cross-sectional study.
Diabetes Obes Metab. 2025 Nov 2. doi: 10.1111/dom.70245.
PubMed
Abstract available
Continuous glucose monitoring in early gestational diabetes improves maternal and
neonatal outcomes-The Steady Sugar trial.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70254.
PubMed
Abstract available
Impact of sotagliflozin on glomerular hyperfiltration in people with type 1
diabetes: A post hoc analysis of the inTandem3 trial.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70266.
PubMed
Synergistic associations of metformin and GLP-1 receptor agonist use with
adiposity-related cancer incidence in people living with type 2 diabetes.
Diabetes Obes Metab. 2025 Nov 3. doi: 10.1111/dom.70267.
PubMed
Abstract available
I-BET151 modulates glucokinase gene expression and beta cell function in part
through changes in FOXO1 expression.
Diabetologia. 2025;68:2767-2780.
PubMed
Abstract available
Complete loss of SLC30A8 in humans improves glucose metabolism and beta cell
function.
Diabetologia. 2025;68:2754-2766.
PubMed
Abstract available
Daily life stress is linked to increased glucose levels in individuals with
insulin resistance: a real-world assessment.
Diabetologia. 2025;68:2709-2718.
PubMed
Abstract available
Sexual orientation, gender identity and cardiometabolic risk: a narrative review.
Diabetologia. 2025;68:2652-2669.
PubMed
Abstract available
Heterogeneity in clinically diagnosed type 1 diabetes: characterising a unique
cohort with maintained C-peptide secretion in Ghana.
Diabetologia. 2025 Nov 1. doi: 10.1007/s00125-025-06576.
PubMed
Abstract available
Safety and pharmacokinetics of teplizumab in children less than 8 years of age
with stage 2 type 1 diabetes.
Diabetologia. 2025 Nov 6. doi: 10.1007/s00125-025-06586.
PubMed
Abstract available
Effectiveness of video consultations in type 1 diabetes patients treated with
insulin pumps in the outpatient clinic: a randomised controlled trial.
Diabetologia. 2025 Nov 7. doi: 10.1007/s00125-025-06585.
PubMed
Abstract available
Liver fat content is not elevated in people with type 1 diabetes: the Maastricht
Study.
Diabetologia. 2025 Nov 7. doi: 10.1007/s00125-025-06597.
PubMed
Abstract available
Retraction of: VEGF as a Survival Factor in Ex Vivo Models of Early Diabetic
Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed
DJ-1 Protects Human Retinal Endothelial Cells From Diabetes-Related Conditions
and Prevents Ischemic Damage in Mouse Retinal Capillaries.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed
Abstract available
The Association of Retinal Capillary Density and Retinal Thickness in Diabetic
Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed
Abstract available
Dipeptidyl Peptidase 4, a Novel Adipokine, Impairs Retinal Microcirculation in
Patients With Type 2 Diabetes Mellitus.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed
Abstract available
Mapping cellular cytosolic pH in vivo under physiological and pathophysiological
conditions.
J Biol Chem. 2025;301:110637.
PubMed
Abstract available
Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone
Microarchitecture in Type 2 Diabetes: A Pilot Trial.
J Clin Endocrinol Metab. 2025 Nov 3:dgaf589. doi: 10.1210.
PubMed
Abstract available
Glucometabolic control and Anti-Transglutaminase Antibodies at Celiac Disease
onset in Type 1 Diabetes youth.
J Clin Endocrinol Metab. 2025 Nov 4:dgaf604. doi: 10.1210.
PubMed
Abstract available
Neutrophils take center stage in VEXAS syndrome pathogenesis.
J Clin Invest. 2025;135:e199299.
PubMed
Abstract available
Antiinflammatory actions of glucagon-like peptide-1-based therapies beyond
metabolic benefits.
J Clin Invest. 2025;135:e194751.
PubMed
Abstract available
GLP-1 agonists in the treatment of chronic kidney disease in type 2 diabetes and
obesity.
J Clin Invest. 2025;135:e194749.
PubMed
Abstract available
GLP-1 receptor agonists and cancer: current clinical evidence and translational
opportunities for preclinical research.
J Clin Invest. 2025;135:e194743.
PubMed
Abstract available
Soluble tumor necrosis factor receptors (sTNFRs) as biomarkers for diabetic
kidney disease: Soluble TNF receptors and DKD.
J Diabetes Complications. 2025;40:109204.
PubMed
Abstract available
Glycemia, management and outcomes of pregnant women with maturity-onset diabetes
of the young - a single-center case series.
J Diabetes Complications. 2025;40:109206.
PubMed
Abstract available
Data-driven subtypes of newly diagnosed youth-onset type 2 diabetes in the USA.
J Diabetes Complications. 2025;40:109207.
PubMed
Abstract available
The role of oral alpha-lipoic acid as an adjuvant antioxidant therapy in diabetic
nephropathy among children and adolescents with type 1 diabetes: a randomized
controlled trial.
J Diabetes Complications. 2025;40:109201.
PubMed
Abstract available
Identification of biomarkers to predict renal function decline and its
deceleration in patients with type 2 diabetes and diabetic kidney disease.
J Diabetes Complications. 2025;40:109208.
PubMed
Abstract available
The impact of blood pressure variability on cardiovascular and renal outcomes in
patients with and without diabetes: insights from the Anglo-Scandinavian Cardiac
Outcomes Trial.
J Hypertens. 2025;43:2033-2041.
PubMed
Abstract available
Hypertensive disorders of pregnancy increase the risk of future ophthalmic
disorders: a systematic review and meta-analysis.
J Hypertens. 2025;43:1903-1911.
PubMed
Abstract available
Arterial stiffness is associated with small and large fiber neuropathy: The
Maastricht Study.
J Hypertens. 2025;43:1945-1952.
PubMed
Abstract available
FDA Approves GLP-1 Pill for Cardiovascular Risk in Type 2 Diabetes.
JAMA. 2025 Nov 7. doi: 10.1001/jama.2025.19724.
PubMed
Lifestyle intervention is more effective in high 1-hour post-load glucose than in
prediabetes for restoring beta-cell function, reducing ectopic fat, and preventing
type 2 diabetes.
Metabolism. 2025 Nov 3:156430. doi: 10.1016/j.metabol.2025.156430.
PubMed
Abstract available
Foveal Avascular Zone Enlargement Significantly Improves Statistical Models for
Detection of Diabetic Retinopathy Severity.
Ophthalmol Retina. 2025 Nov 4:S2468-6530(25)00502.
PubMed
Abstract available
HLA-C? ( *) 0304 Associates With Beneficial Gut Microbiota and Later Onset of Type
1 Diabetes in Pediatric Cohorts.
Pediatr Diabetes. 2025;2025:3013063.
PubMed
Abstract available
Caring Under Constraints: A Qualitative Study of Parental Needs in Pediatric
Diabetes in Zabol.
Pediatr Diabetes. 2025;2025:4306754.
PubMed
Abstract available
Depressive Symptoms and Glycemic Control Among Children and Adolescents With
Diabetes: The Mediation Effect of Self-Care Behaviors.
Pediatr Diabetes. 2025;2025:8850165.
PubMed
Abstract available
Single-cell sequencing reveals the response mechanisms of vascular endothelial
cells to glucocorticoids in diabetic retinopathy.
PLoS One. 2025;20:e0334230.
PubMed
Abstract available
Association of erythropoietin gene polymorphism (rs1617640 C>T/G) with diabetic
retinopathy in Type 2 diabetes mellitus patients of Punjabi population in
Pakistan.
PLoS One. 2025;20:e0336014.
PubMed
Abstract available
Comparative effectiveness of biguanides versus SGLT2 inhibitors on cardiovascular
and cerebrovascular events, diabetic nephropathy, retinopathy, neuropathy, and
treatment expenditures in patients with type 2 diabetes.
PLoS One. 2025;20:e0336038.
PubMed
Abstract available
GCMS profiling of bioactive phytocompounds from Curculigo orchiodes Gaertn. root
extract and evaluation of antioxidant, and antidiabetic activities: A
computational drug development approach.
PLoS One. 2025;20:e0335403.
PubMed
Abstract available
Correction: Counterintuitive relationship between the triglyceride glucose index
and diabetic foot in diabetes patients: A cross-sectional study.
PLoS One. 2025;20:e0336351.
PubMed
Abstract available
Self-management of type 2 diabetes using a co-designed text based mobile health
(mHealth) intervention in Nepal: A study protocol for randomised controlled
trial.
PLoS One. 2025;20:e0335333.
PubMed
Abstract available
Identification of Seven in absentia homolog 2 as a potential
efferocytosis-related biomarker in diabetic foot ulcers.
PLoS One. 2025;20:e0334163.
PubMed
Abstract available
Who presents the greatest challenge in intellectual disability research-
participants or health and research professionals?
PLoS One. 2025;20:e0332744.
PubMed
Abstract available
Correction: Diabetes rescue, engagement, and management (D-REM) for hypoglycemia:
Clinical trial protocol of a community paramedic program to improve diabetes
management among adults with severe hypoglycemia.
PLoS One. 2025;20:e0336047.
PubMed
Abstract available
Evaluation of Etiology Based on Post-Transplant Pathological Diagnosis in Cases
of Cryptogenic Cirrhosis.
Transplant Proc. 2025 Sep 16:S0041-1345(25)00384.
PubMed
Abstract available
Total Pancreatectomy and Islet Autotransplantation for Chronic Pancreatitis
Relieves Pain and Mitigates Diabetes Development.
WMJ. 2025;124:326-332.
PubMed
Abstract available
Thank you for your interest in scientific medicine.