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  Diabetes

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29.09.2025

1 Am J Manag Care
1 Am J Ophthalmol
1 Angiology
1 Biochem Biophys Res Commun
1 Diabet Med
6 Diabetes
13 Diabetes Care
9 Diabetes Obes Metab
4 Diabetologia
1 Eur J Endocrinol
3 J Clin Endocrinol Metab
1 Kidney Int
5 Lancet
1 Nature
1 Pediatr Diabetes
1 PLoS Med
6 PLoS One
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Manag Care

  1. LIU G, Jarema M, Mo M, Stievater T, et al
    Navigating compounded semaglutide: what health care providers need to know.
    Am J Manag Care. 2025;31:480-484.
    PubMed         Abstract available


    Am J Ophthalmol

  2. FAN Y, Li L, Wu X, Yan Y, et al
    Longitudinal neural and microvascular changes in type 2 diabetic patients without retinopathy: a 2-year prospective cohort study.
    Am J Ophthalmol. 2025 Sep 19:S0002-9394(25)00503.
    PubMed         Abstract available


    Angiology

  3. ZHOU JL, Sun BS, Li T
    Serum Creatinine/Cystatin C as a Novel Biomarker of Atherosclerosis in Patients With Type 2 Diabetes Mellitus.
    Angiology. 2025 Sep 24:33197251368948. doi: 10.1177/00033197251368948.
    PubMed        


    Biochem Biophys Res Commun

  4. CHENG Y, Liu G, Yu L, Li H, et al
    A related mechanism for USP18 regulating diabetic cardiomyopathy procession: promoting activity of AKT signaling pathway by improving Notch1 stability.
    Biochem Biophys Res Commun. 2025;784:152626.
    PubMed         Abstract available


    Diabet Med

  5. BESSER REJ, Campbell F, Damazer K, Elleri D, et al
    UK best practice recommendations for children and young people <18 years with pre-stage 3 type 1 diabetes, on behalf of the British Society for Paediatric Endocrinology and Diabetes (BSPED).
    Diabet Med. 2025 Sep 23:e70117. doi: 10.1111/dme.70117.
    PubMed         Abstract available


    Diabetes

  6. PAGE B
    Diabetes Spotlight: Rebecca Anne Haeusler, PhD-Investigating Metabolism Through Insulin Signaling.
    Diabetes. 2025;74:1709.
    PubMed        

  7. RAGHAVAN S, Litkowski E, Jensen A, Charest B, et al
    Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program.
    Diabetes. 2025 Sep 19:db250304. doi: 10.2337/db25-0304.
    PubMed         Abstract available

  8. CARTWRIGHT BR, Scherer PE
    Adipose Tissue as a Target for Precision Medicine Approaches in Childhood Obesity.
    Diabetes. 2025 Aug 12:dbi240044. doi: 10.2337/dbi24-0044.
    PubMed         Abstract available

  9. HU X, Guo L, Pilar Toledo M, Sandoval Sanchez P, et al
    Molecular Mechanisms of Human Pancreatic Islet Dysfunction Under Overnutrition Metabolic Stress.
    Diabetes. 2025;74:1825-1838.
    PubMed         Abstract available

  10. JIA RY, Chen JH, Lockhart S, Lam BYH, et al
    Bidirectional Mendelian Randomization Indicates Causal Relationships Between Circulating Branched-Chain Amino Acids and Metabolic Health.
    Diabetes. 2025;74:1863-1872.
    PubMed         Abstract available

  11. PEARSON ER, Del Prato S, Pavo I, Franco DR, et al
    Predictors of Initial and Sustained Glycemic and Weight Response to Tirzepatide: A Post Hoc Analysis of SURPASS-4.
    Diabetes. 2025;74:1850-1862.
    PubMed         Abstract available


    Diabetes Care

  12. LJUNGBERG C, Norgaard M, Vandenbroucke-Grauls C, Jakobsen JK, et al
    Risk of Phimosis Associated With SGLT2i Versus GLP-1RA: A Danish Cohort Study.
    Diabetes Care. 2025;48:1774-1782.
    PubMed         Abstract available

  13. WANG Y, Liu Z
    Response to Comment on Wang et al. Transition of BMI Status From Childhood to Adulthood and Cardiovascular-Kidney-Metabolic Syndrome in Midlife: A 36-Year Cohort Study. Diabetes Care 2025;48:XXXX-XXXX.
    Diabetes Care. 2025 Sep 18:dci250102. doi: 10.2337/dci25-0102.
    PubMed        

  14. AGARWAL R, Green JB, Heerspink HJL, Mann JFE, et al
    Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial).
    Diabetes Care. 2025 Sep 19:dc251673. doi: 10.2337/dc25-1673.
    PubMed         Abstract available

  15. JANCEV M, Eliasson B, Gerstein HC, Eeg-Olofsson K, et al
    Dementia Risk in People With Type 1 Diabetes and Associated Risk Factors: A Nationwide, Register-Based Cohort Study.
    Diabetes Care. 2025 Sep 19:dc250773. doi: 10.2337/dc25-0773.
    PubMed         Abstract available

  16. BEE YM, Awasthi N, Gandhi M, Lam AYR, et al
    Effectiveness of an Incentives-Enhanced Stepped Care Intervention Program in Diabetes Prevention in a Multiethnic Asian Prediabetes Cohort: Results From the Pre-DICTED Randomized Controlled Trial.
    Diabetes Care. 2025 Sep 19:dc251555. doi: 10.2337/dc25-1555.
    PubMed         Abstract available

  17. WALDENMAIER D, Wehrstedt S, Eichenlaub M, Pleus S, et al
    Response to Comments on Freckmann et al. A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitoring Systems. Diabetes Care 2025;48:1213-1217.
    Diabetes Care. 2025;48:e128-e129.
    PubMed        

  18. PAGE B
    About the Editor: Emily K. Sims, MD-Identifying Biomarkers to Delay the Onset of Type 1 Diabetes.
    Diabetes Care. 2025;48:1650.
    PubMed        

  19. BECK RW
    Comment on Freckmann et al. A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitors. Diabetes Care 2025;48:1213-1217.
    Diabetes Care. 2025;48:e124-e125.
    PubMed        

  20. MANTOVANI A, Targher G
    Response to Comment on Mantovani et al. Sodium-Glucose Cotransporter 2 Inhibitor Use and Risk of Liver-Related Events in Patients With Type 2 Diabetes: A Meta-analysis of Observational Cohort Studies. Diabetes Care 2025;48:1042-1052.
    Diabetes Care. 2025;48:e132.
    PubMed        

  21. HANNON TS
    Physical Activity Support Can Improve Outcomes in Youth With Type 1 Diabetes.
    Diabetes Care. 2025;48:1719-1720.
    PubMed        

  22. SHERIFALI DT, Racey ME, Greenway MK, Alliston PE, et al
    Type 2 Diabetes Remission: A Systematic Review and Meta-analysis of Nonsurgical Randomized Controlled Trials.
    Diabetes Care. 2025 Sep 22:dc250562. doi: 10.2337/dc25-0562.
    PubMed         Abstract available

  23. KUO CH, Lin MW, Chen SC, Yen IW, et al
    The Effect of Midpregnancy Screening for Gestational Diabetes Mellitus on Pregnancy Outcomes: The TESGO Randomized Controlled Trial.
    Diabetes Care. 2025 Sep 23:dc250084. doi: 10.2337/dc25-0084.
    PubMed         Abstract available

  24. POP-BUSUI R, Rosin SP, Butera NM, Krause-Steinrauf H, et al
    Differences in Prevalence and Incidence of Electrocardiogram Abnormalities and Cardiovascular Autonomic Neuropathy Among Randomized Glucose-Lowering Treatments in Early Type 2 Diabetes: The Glycemia Reduction Approaches in Diabetes (GRADE) Cohort.
    Diabetes Care. 2025 Sep 23:dc251087. doi: 10.2337/dc25-1087.
    PubMed         Abstract available


    Diabetes Obes Metab

  25. FADINI GP, Longato E, Poletto S, Giaccari A, et al
    Effectiveness of oral semaglutide versus empagliflozin for the management of type 2 diabetes. PIONEER-2 trial emulation with real-world data.
    Diabetes Obes Metab. 2025 Sep 24. doi: 10.1111/dom.70151.
    PubMed         Abstract available

  26. CASTRILLON F, Carter B, McClure A, Welk B, et al
    The impact of semaglutide on peri-operative cardiovascular outcomes in diabetes.
    Diabetes Obes Metab. 2025 Sep 24. doi: 10.1111/dom.70145.
    PubMed        

  27. CHENG J, Yu H, Gu Y, Ma C, et al
    Diabetes remission and diabetic complications of bariatric surgery vs. medical management in patients with type 2 diabetes: A meta-analysis of randomized controlled trials.
    Diabetes Obes Metab. 2025 Sep 24. doi: 10.1111/dom.70152.
    PubMed         Abstract available

  28. ZHANG L, Wang J, Zheng W, Yuan X, et al
    Probiotics and dietary fibre fermented milk supplementation initiated in the first trimester to prevent gestational diabetes mellitus in overweight and obese pregnant women: A randomized controlled trial.
    Diabetes Obes Metab. 2025 Sep 24. doi: 10.1111/dom.70158.
    PubMed         Abstract available

  29. BELAND-BONENFANT S, Denimal D, Pais-de-Barros JP, Choubley H, et al
    Plasma sphingolipids predict advanced liver fibrosis development in patients with type 2 diabetes.
    Diabetes Obes Metab. 2025 Sep 24. doi: 10.1111/dom.70156.
    PubMed         Abstract available

  30. SUN Y, Li H, Yan X, Ma G, et al
    Unveiling urinary diagnostic biomarkers for diabetic kidney disease using metabolomics and machine learning approaches.
    Diabetes Obes Metab. 2025 Sep 21. doi: 10.1111/dom.70138.
    PubMed         Abstract available

  31. RITTENHOUSE BE, Alolayan S, Segal AR, Eguale T, et al
    Reply to "A comment on 'Metformin in the Diabetes Prevention Program 3-year trial: The cost-effectiveness that never was'".
    Diabetes Obes Metab. 2025 Sep 18. doi: 10.1111/dom.70149.
    PubMed        

  32. DIONNE V, Iglesies-Grau J, Latour E, Besnier F, et al
    Optimizing cardiovascular health with a type 2 diabetes remission program: Ultraprocessed food-intake reduction, Mediterranean diet, chrononutrition and physical training-The DIABEPIC-2 pilot study.
    Diabetes Obes Metab. 2025 Sep 18. doi: 10.1111/dom.70142.
    PubMed         Abstract available

  33. QU HQ, Hakonarson H
    Sex as a modifier of genetic risk for type 1 diabetes.
    Diabetes Obes Metab. 2025 Sep 18. doi: 10.1111/dom.70124.
    PubMed         Abstract available


    Diabetologia

  34. DIETLER D, Bjork J, Palmkvist E, Carlsson A, et al
    Trends in type 1 diabetes incidence between 2007 and 2023 and their association with SARS-CoV-2 infection in a population-based matched cohort study among individuals under 30 years old in Sweden.
    Diabetologia. 2025 Sep 18. doi: 10.1007/s00125-025-06540.
    PubMed         Abstract available

  35. KVIST AAS, Sharma A, Qvigstad E, Sattar N, et al
    Differences in tissue-specific insulin resistance between South Asian and Nordic women with prediabetes after gestational diabetes.
    Diabetologia. 2025 Sep 24. doi: 10.1007/s00125-025-06546.
    PubMed         Abstract available

  36. TOLEDO FGS, Li Y, Wang F, Bellin MD, et al
    Pancreatic cancer-related diabetes and type 2 diabetes differ in multiple aspects of glucose homeostasis.
    Diabetologia. 2025 Sep 24. doi: 10.1007/s00125-025-06543.
    PubMed         Abstract available

  37. DYSON NJ, Kattner N, Al-Selwi Y, Honkanen-Scott M, et al
    Quantitative analysis of human adult pancreatic histology reveals separate fatty and fibrotic phenotypes in type 2 diabetes.
    Diabetologia. 2025 Sep 24. doi: 10.1007/s00125-025-06547.
    PubMed         Abstract available


    Eur J Endocrinol

  38. HAN AJ, Achenbach SJ, Atkinson EJ, Bancos I, et al
    Identifying factors associated with subsequent diagnosis of adrenal adenoma: a population-based historical case-control study.
    Eur J Endocrinol. 2025;193:383-390.
    PubMed         Abstract available


    J Clin Endocrinol Metab

  39. LAI KZH, Harris SB, Retnakaran R, Hanley AJG, et al
    Longitudinal Association of Statin Treatment With Insulin Sensitivity and Beta-Cell Function in the PROMISE Cohort.
    J Clin Endocrinol Metab. 2025;110:e3442-e3452.
    PubMed         Abstract available

  40. FISHER M, Smith G, Potter BK, Arbuckle TE, et al
    The Association between Pregnancy Complications and Long-Term Maternal Cardiometabolic Health in the MIREC Cohort Study.
    J Clin Endocrinol Metab. 2025 Jan 23:dgaf041. doi: 10.1210.
    PubMed         Abstract available

  41. ZHOU R, Jiajue R, Ni X, Pang Q, et al
    Glucose Metabolic Abnormalities and Their Interaction With Defective Phosphate Homeostasis in Tumor-induced Osteomalacia.
    J Clin Endocrinol Metab. 2025;110:2869-2878.
    PubMed         Abstract available


    Kidney Int

  42. ORTIZ A, Arreola Guerra JM, Chan JCN, Jha V, et al
    Preventing chronic kidney disease and maintaining kidney health: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
    Kidney Int. 2025 Jun 18:S0085-2538(25)00334-5. doi: 10.1016/j.kint.2025.
    PubMed         Abstract available


    Lancet

  43. HANNON TS, Chao LC, Barrientos-Perez M, Pamidipati KC, et al
    Efficacy and safety of tirzepatide in children and adolescents with type 2 diabetes (SURPASS-PEDS): a randomised, double-blind, placebo-controlled, phase 3 trial.
    Lancet. 2025 Sep 17:S0140-6736(25)01774-X. doi: 10.1016/S0140-6736(25)01774.
    PubMed         Abstract available

  44. MATHIEU C, Wych J, Hendriks AEJ, Van Ryckeghem L, et al
    Minimum effective low dose of antithymocyte globulin in people aged 5-25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.
    Lancet. 2025 Sep 18:S0140-6736(25)01674-5. doi: 10.1016/S0140-6736(25)01674.
    PubMed         Abstract available

  45. SPEAKE C
    ATG as disease-modifying therapy for new-onset type 1 diabetes.
    Lancet. 2025 Sep 18:S0140-6736(25)01773-8. doi: 10.1016/S0140-6736(25)01773.
    PubMed        

  46. ISGANAITIS E, Laffel LM
    Dual incretin agonist for paediatric type 2 diabetes: an eagerly awaited opportunity.
    Lancet. 2025 Sep 19:S0140-6736(25)01908-7. doi: 10.1016/S0140-6736(25)01908.
    PubMed        

  47. ZIEGLER AG, Cengiz E, Kay TWH
    The future of type 1 diabetes therapy.
    Lancet. 2025 Sep 19:S0140-6736(25)01438-2. doi: 10.1016/S0140-6736(25)01438.
    PubMed         Abstract available


    Nature

  48. FIELDHOUSE R
    Gestational diabetes linked to autism in study: what scientists say.
    Nature. 2025 Sep 22. doi: 10.1038/d41586-025-03024.
    PubMed        


    Pediatr Diabetes

  49. LYNAM K, O'Grady MJ
    Increasing Prevalence of Pediatric Type 2 Diabetes in the Republic of Ireland: A National Cross-Sectional Study.
    Pediatr Diabetes. 2025;2025:8892271.
    PubMed         Abstract available


    PLoS Med

  50. WANG L, Tang C, Cheng M, Hao Y, et al
    Association between lower fasting plasma glucose levels during oral glucose tolerance test and adverse perinatal outcomes: A Chinese cohort study.
    PLoS Med. 2025;22:e1004722.
    PubMed         Abstract available


    PLoS One

  51. MARTIZ RM, Ramu R, Nambisan H, Suhail A, et al
    Identification and 3D modeling of bioactive peptides from Lactobacillus brevis RAMULAB49 protein hydrolysate with in silico ERK1 phosphorylation inhibition activity targeting diabetic nephropathy.
    PLoS One. 2025;20:e0331192.
    PubMed         Abstract available

  52. CHONG CT, Palaniveloo L, Husni Zain S, Khalil MKN, et al
    Gestational diabetes mellitus and its associated factors among women of advanced maternal age in Malaysia: Findings from a national survey.
    PLoS One. 2025;20:e0333005.
    PubMed         Abstract available


  53. Retraction: Improved support vector machine based on CNN-SVD for vision-threatening diabetic retinopathy detection and classification.
    PLoS One. 2025;20:e0332845.
    PubMed        

  54. BEKKEN T, Ottesen N, Glenton C, Nordheim LV, et al
    What motivates people with type 2 diabetes to maintain lifestyle changes and what challenges do they experience? A qualitative evidence synthesis.
    PLoS One. 2025;20:e0332276.
    PubMed         Abstract available

  55. ASRIE AB, Belete TM, Misker MF, Beyna AT, et al
    Assessment of glycemic control, health-related quality of life, and associated factors in type 2 diabetic patients attending a comprehensive specialized hospital in Northwest Ethiopia.
    PLoS One. 2025;20:e0332628.
    PubMed         Abstract available

  56. ESPINOZA-ENCISO LF, Hernandez-Gozar IG, Zuniga-Baldarrago KC, Lozano-Purizaca R, et al
    Prevalence of peripheral arterial disease and arterial calcification based on three ankle-brachial index calculation methods (highest, average, and lowest systolic ankle pressure): A cross-sectional study in Type 2 diabetes mellitus patients in Peru.
    PLoS One. 2025;20:e0316981.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  57. MA E, Schafer CM, Xie J, Rudenko Y, et al
    Targeting endothelial ERG to mitigate vascular regression in retinopathies.
    Proc Natl Acad Sci U S A. 2025;122:e2507194122.
    PubMed         Abstract available


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