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Articles published in Invest Ophthalmol Vis Sci

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    March 2021

  1. Erratum in: Peripapillary Retinal Nerve Fiber Layer and Microvasculature in Prolonged Type 2 Diabetes Patients Without Clinical Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2021;62:10.
    PubMed    


  2. BISWAS S, Feng B, Chen S, Liu J, et al
    The Long Non-Coding RNA HOTAIR Is a Critical Epigenetic Mediator of Angiogenesis in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2021;62:20.
    PubMed     Abstract available


  3. MONTESANO G, Ometto G, Higgins BE, Das R, et al
    Evidence for Structural and Functional Damage of the Inner Retina in Diabetes With No Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2021;62:35.
    PubMed     Abstract available


  4. FAN S, Yang Z, Liu Y, Zhong J, et al
    Extensive Sub-RPE Complement Deposition in a Nonhuman Primate Model of Early-Stage Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2021;62:30.
    PubMed     Abstract available


    February 2021
  5. LI H, Chen D, Sun W, Chen J, et al
    KATP Opener Attenuates Diabetic-Induced Muller Gliosis and Inflammation by Modulating Kir6.1 in Microglia.
    Invest Ophthalmol Vis Sci. 2021;62:3.
    PubMed     Abstract available


  6. ZHOU W, Yang J, Wang Q, Wang Y, et al
    Systemic Stressors and Retinal Microvascular Alterations in People Without Diabetes: The Kailuan Eye Study.
    Invest Ophthalmol Vis Sci. 2021;62:20.
    PubMed     Abstract available


  7. LEE MW, Lee WH, Ryu CK, Lee YM, et al
    Peripapillary Retinal Nerve Fiber Layer and Microvasculature in Prolonged Type 2 Diabetes Patients Without Clinical Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2021;62:9.
    PubMed     Abstract available


    January 2021
  8. TSAI ASH, Jordan-Yu JM, Gan ATL, Teo KYC, et al
    Diabetic Macular Ischemia: Influence of Optical Coherence Tomography Angiography Parameters on Changes in Functional Outcomes Over One Year.
    Invest Ophthalmol Vis Sci. 2021;62:9.
    PubMed     Abstract available


    December 2020
  9. MIN JW, Kim HD, Park SY, Lee JH, et al
    Relationship Between Retinal Capillary Nonperfusion Area and Renal Function in Patients With Type 2 Diabetes.
    Invest Ophthalmol Vis Sci. 2020;61:14.
    PubMed     Abstract available


  10. WANG J, Xin X, Luo W, Wang R, et al
    Anemia and Diabetic Kidney Disease Had Joint Effect on Diabetic Retinopathy Among Patients With Type 2 Diabetes.
    Invest Ophthalmol Vis Sci. 2020;61:25.
    PubMed     Abstract available


  11. MOHAMMAD G, Radhakrishnan R, Kowluru RA
    Hydrogen Sulfide: A Potential Therapeutic Target in the Development of Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:35.
    PubMed     Abstract available


  12. WU D, Kanda A, Liu Y, Noda K, et al
    Involvement of Muller Glial Autoinduction of TGF-beta in Diabetic Fibrovascular Proliferation Via Glial-Mesenchymal Transition.
    Invest Ophthalmol Vis Sci. 2020;61:29.
    PubMed     Abstract available


    November 2020
  13. CHEN H, Zhang X, Liao N, Ji Y, et al
    Identification of NLRP3 Inflammation-Related Gene Promoter Hypomethylation in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:12.
    PubMed     Abstract available


    October 2020
  14. CHAO C, Wang R, Jones M, Karson N, et al
    The Relationship Between Corneal Nerve Density and Hemoglobin A1c in Patients With Prediabetes and Type 2 Diabetes.
    Invest Ophthalmol Vis Sci. 2020;61:26.
    PubMed     Abstract available


    September 2020
  15. ROBINSON R, Youngblood H, Iyer H, Bloom J, et al
    Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition.
    Invest Ophthalmol Vis Sci. 2020;61:2.
    PubMed     Abstract available


  16. CHOI MG, Chung H, Yoon YH, Kim JT, et al
    Effects of Systemic Profiles on Choroidal Thickness in Treatment-Naive Eyes With Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:12.
    PubMed     Abstract available


  17. MANDAVA N, Tirado-Gonzalez V, Geiger MD, Patnaik JL, et al
    Complement Activation in the Vitreous of Patients With Proliferative Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:39.
    PubMed     Abstract available


  18. JIANG Y, Steinle JJ
    Epac1 Requires AMPK Phosphorylation to Regulate HMGB1 in the Retinal Vasculature.
    Invest Ophthalmol Vis Sci. 2020;61:33.
    PubMed     Abstract available


    August 2020
  19. NG KKK, Cheung CYY, Lee CH, Fong CHY, et al
    Possible Modifying Effect of Hemoglobin A1c on Genetic Susceptibility to Severe Diabetic Retinopathy in Patients With Type 2 Diabetes.
    Invest Ophthalmol Vis Sci. 2020;61:7.
    PubMed     Abstract available


  20. KIM D, Roy S
    Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:10.
    PubMed     Abstract available


  21. LIM HB, Shin YI, Lee MW, Lee JU, et al
    Association of Myopia with Peripapillary Retinal Nerve Fiber Layer Thickness in Diabetic Patients Without Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:30.
    PubMed     Abstract available


  22. MAZZOLI V, Zhong LH, Dang VT, Shi Y, et al
    Characterization of Retinal Microvascular Complications and the Effects of Endoplasmic Reticulum Stress in Mouse Models of Diabetic Atherosclerosis.
    Invest Ophthalmol Vis Sci. 2020;61:49.
    PubMed     Abstract available


  23. IVANOVA E, Bianchimano P, Corona C, Eleftheriou CG, et al
    Optogenetic Stimulation of Cholinergic Amacrine Cells Improves Capillary Blood Flow in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:44.
    PubMed     Abstract available


  24. ASHRAF M, Sampani K, Clermont A, Abu-Qamar O, et al
    Vascular Density of Deep, Intermediate and Superficial Vascular Plexuses Are Differentially Affected by Diabetic Retinopathy Severity.
    Invest Ophthalmol Vis Sci. 2020;61:53.
    PubMed     Abstract available


  25. LIN HZ, Hsieh TC, Wu JL, He MS, et al
    Systemic Alpha1-Adrenoceptor Antagonists and Increased Risk of Open-Angle Glaucoma: A Nationwide Population-Based Cohort Study.
    Invest Ophthalmol Vis Sci. 2020;61:15.
    PubMed     Abstract available


    June 2020
  26. RO-MASE T, Ishiko S, Omae T, Ishibazawa A, et al
    Association Between Alterations of the Choriocapillaris Microcirculation and Visual Function and Cone Photoreceptors in Patients With Diabetes.
    Invest Ophthalmol Vis Sci. 2020;61:1.
    PubMed     Abstract available


  27. SOUSA DC, Leal I, Moreira S, do Vale S, et al
    Retinal Vascular Reactivity in Type 1 Diabetes Patients Without Retinopathy Using Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2020;61:49.
    PubMed     Abstract available


  28. ALEX A, Luo Q, Mathew D, Di R, et al
    Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in Diabetes.
    Invest Ophthalmol Vis Sci. 2020;61:46.
    PubMed     Abstract available


  29. WU D, Noda K, Murata M, Liu Y, et al
    Regulation of Spermine Oxidase through Hypoxia-Inducible Factor-1alpha Signaling in Retinal Glial Cells under Hypoxic Conditions.
    Invest Ophthalmol Vis Sci. 2020;61:52.
    PubMed     Abstract available


    May 2020
  30. KARST SG, Heisler M, Lo J, Schuck N, et al
    Evaluating Signs of Microangiopathy Secondary to Diabetes in Different Areas of the Retina with Swept Source OCTA.
    Invest Ophthalmol Vis Sci. 2020;61:8.
    PubMed     Abstract available


  31. HEIN TW, Omae T, Xu W, Yoshida A, et al
    Role of Arginase in Selective Impairment of Endothelium-Dependent Nitric Oxide Synthase-Mediated Dilation of Retinal Arterioles during Early Diabetes.
    Invest Ophthalmol Vis Sci. 2020;61:36.
    PubMed     Abstract available


  32. LI X, Xie J, Zhang L, Cui Y, et al
    Identifying Microvascular and Neural Parameters Related to the Severity of Diabetic Retinopathy Using Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2020;61:39.
    PubMed     Abstract available


    April 2020
  33. WANG W, Liu S, Qiu Z, He M, et al
    Choroidal Thickness in Diabetes and Diabetic Retinopathy: A Swept Source OCT Study.
    Invest Ophthalmol Vis Sci. 2020;61:29.
    PubMed     Abstract available


  34. NGUYEN NH, Kim D, Roy S
    High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:40.
    PubMed     Abstract available


  35. AN D, Chandrasekera E, Yu DY, Balaratnasingam C, et al
    Non-Proliferative Diabetic Retinopathy Is Characterized by Nonuniform Alterations of Peripapillary Capillary Networks.
    Invest Ophthalmol Vis Sci. 2020;61:39.
    PubMed     Abstract available


  36. KWAN CC, Lee HE, Schwartz G, Fawzi AA, et al
    Acute Hyperglycemia Reverses Neurovascular Coupling During Dark to Light Adaptation in Healthy Subjects on Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2020;61:38.
    PubMed     Abstract available


    March 2020
  37. CHOI EY, Park SE, Lee SC, Koh HJ, et al
    Association Between Clinical Biomarkers and Optical Coherence Tomography Angiography Parameters in Type 2 Diabetes Mellitus.
    Invest Ophthalmol Vis Sci. 2020;61:4.
    PubMed     Abstract available


  38. SHIMOUCHI A, Ishibazawa A, Ishiko S, Omae T, et al
    A Proposed Classification of Intraretinal Microvascular Abnormalities in Diabetic Retinopathy Following Panretinal Photocoagulation.
    Invest Ophthalmol Vis Sci. 2020;61:34.
    PubMed     Abstract available


  39. MARQUES IP, Alves D, Santos T, Mendes L, et al
    Characterization of Disease Progression in the Initial Stages of Retinopathy in Type 2 Diabetes: A 2-Year Longitudinal Study.
    Invest Ophthalmol Vis Sci. 2020;61:20.
    PubMed     Abstract available


  40. FERDOUSI M, Kalteniece A, Petropoulos I, Azmi S, et al
    Diabetic Neuropathy Is Characterized by Progressive Corneal Nerve Fiber Loss in the Central and Inferior Whorl Regions.
    Invest Ophthalmol Vis Sci. 2020;61:48.
    PubMed     Abstract available


  41. DAI Y, Zhou H, Chu Z, Zhang Q, et al
    Microvascular Changes in the Choriocapillaris of Diabetic Patients Without Retinopathy Investigated by Swept-Source OCT Angiography.
    Invest Ophthalmol Vis Sci. 2020;61:50.
    PubMed     Abstract available


    February 2020
  42. ALI Z, Zang J, Lagali N, Schmitner N, et al
    Photoreceptor Degeneration Accompanies Vascular Changes in a Zebrafish Model of Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:43.
    PubMed     Abstract available


  43. WU F, Phone A, Lamy R, Ma D, et al
    Correlation of Aqueous, Vitreous, and Plasma Cytokine Levels in Patients With Proliferative Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2020;61:26.
    PubMed     Abstract available


  44. DIERSCHKE SK, Toro AL, Barber AJ, Arnold AC, et al
    Angiotensin-(1-7) Attenuates Protein O-GlcNAcylation in the Retina by EPAC/Rap1-Dependent Inhibition of O-GlcNAc Transferase.
    Invest Ophthalmol Vis Sci. 2020;61:24.
    PubMed     Abstract available


    November 2019
  45. BAO YK, Yan Y, Gordon M, McGill JB, et al
    Visual Field Loss in Patients With Diabetes in the Absence of Clinically-Detectable Vascular Retinopathy in a Nationally Representative Survey.
    Invest Ophthalmol Vis Sci. 2019;60:4711-4716.
    PubMed     Abstract available


  46. KARST SG, Beiglboeck H, Scharinger R, Meyer EL, et al
    Retinal and Choroidal Perfusion Status in the Area of Laser Scars Assessed With Swept-Source Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2019;60:4865-4871.
    PubMed     Abstract available


    October 2019
  47. LI Y, Chen D, Sun L, Wu Y, et al
    Induced Expression of VEGFC, ANGPT, and EFNB2 and Their Receptors Characterizes Neovascularization in Proliferative Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:4084-4096.
    PubMed     Abstract available


  48. ISHIBAZAWA A, De Pretto LR, Alibhai AY, Moult EM, et al
    Retinal Nonperfusion Relationship to Arteries or Veins Observed on Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:4310-4318.
    PubMed     Abstract available


  49. GU C, Draga D, Zhou C, Su T, et al
    miR-590-3p Inhibits Pyroptosis in Diabetic Retinopathy by Targeting NLRP1 and Inactivating the NOX4 Signaling Pathway.
    Invest Ophthalmol Vis Sci. 2019;60:4215-4223.
    PubMed     Abstract available


  50. OZAKI K, Terayama Y, Matsuura T
    Hyperglycemia Suppresses Age-Related Increases in Corneal Peripheral Sensory Nerves in Wistar Bon Kobori (WBN/Kob) Rats.
    Invest Ophthalmol Vis Sci. 2019;60:4151-4158.
    PubMed     Abstract available


    September 2019
  51. PETERSEN L, Bek T
    The Oxygen Saturation in Vascular Abnormalities Depends on the Extent of Arteriovenous Shunting in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:3762-3767.
    PubMed     Abstract available


  52. LOPES DE FARIA JM, Duarte DA, Simo R, Garcia-Ramirez M, et al
    delta Opioid Receptor Agonism Preserves the Retinal Pigmented Epithelial Cell Tight Junctions and Ameliorates the Retinopathy in Experimental Diabetes.
    Invest Ophthalmol Vis Sci. 2019;60:3842-3853.
    PubMed     Abstract available


  53. MOHAMMAD G, Radhakrishnan R, Kowluru RA
    Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:3943-3951.
    PubMed     Abstract available


  54. LIU E, Kaidonis G, McComish BJ, Gillies MC, et al
    MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus.
    Invest Ophthalmol Vis Sci. 2019;60:3937-3942.
    PubMed     Abstract available


  55. MOORE-DOTSON JM, Eggers ED
    Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells.
    Invest Ophthalmol Vis Sci. 2019;60:4063-4073.
    PubMed     Abstract available


    August 2019
  56. HUA R, Qu L, Ma B, Yang P, et al
    Diabetic Optic Neuropathy and Its Risk Factors in Chinese Patients With Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:3514-3519.
    PubMed     Abstract available


  57. TSAI MJ, Cheng CK, Wang YC
    Association of Body Fluid Expansion With Optical Coherence Tomography Measurements in Diabetic Retinopathy and Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2019;60:3606-3612.
    PubMed     Abstract available


  58. WANG Q, Wang YX, Wu SL, Chen SH, et al
    Ocular Axial Length and Diabetic Retinopathy: The Kailuan Eye Study.
    Invest Ophthalmol Vis Sci. 2019;60:3689-3695.
    PubMed     Abstract available


    July 2019
  59. SUMARRIVA K, Uppal K, Ma C, Herren DJ, et al
    Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:3119-3126.
    PubMed     Abstract available


  60. NAMBA R, Kaneko H, Suzumura A, Shimizu H, et al
    In Vitro Epiretinal Membrane Model and Antibody Permeability: Relationship With Anti-VEGF Resistance in Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2019;60:2942-2949.
    PubMed     Abstract available


    June 2019
  61. ASHIMATEY BS, Green KM, Chu Z, Wang RK, et al
    Impaired Retinal Vascular Reactivity in Diabetic Retinopathy as Assessed by Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2019;60:2468-2473.
    PubMed     Abstract available


  62. CARROLL LS, Uehara H, Fang D, Choi S, et al
    Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina.
    Invest Ophthalmol Vis Sci. 2019;60:2494-2502.
    PubMed     Abstract available


  63. YAMAMOTO M, Fujihara K, Ishizawa M, Osawa T, et al
    Overt Proteinuria, Moderately Reduced eGFR and Their Combination Are Predictive of Severe Diabetic Retinopathy or Diabetic Macular Edema in Diabetes.
    Invest Ophthalmol Vis Sci. 2019;60:2685-2689.
    PubMed     Abstract available


    May 2019
  64. LUO Q, Xiao Y, Alex A, Cummins TR, et al
    The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1.
    Invest Ophthalmol Vis Sci. 2019;60:1928-1936.
    PubMed     Abstract available


  65. DUMPALA S, Zele AJ, Feigl B
    Outer Retinal Structure and Function Deficits Contribute to Circadian Disruption in Patients With Type 2 Diabetes.
    Invest Ophthalmol Vis Sci. 2019;60:1870-1878.
    PubMed     Abstract available


  66. LYNCH SK, Lee K, Chen Z, Folk JC, et al
    Intravitreal Fluocinolone Acetonide May Decelerate Diabetic Retinal Neurodegeneration.
    Invest Ophthalmol Vis Sci. 2019;60:2134-2139.
    PubMed     Abstract available


  67. MORJARIA R, Alexander I, Purbrick RMJ, Safa R, et al
    Impact of Diabetic Retinopathy on Sleep, Mood, and Quality of Life.
    Invest Ophthalmol Vis Sci. 2019;60:2304-2310.
    PubMed     Abstract available


  68. GRAUSLUND J, Frydkjaer-Olsen U, Peto T, Fernandez-Carneado J, et al
    Topical Treatment With Brimonidine and Somatostatin Causes Retinal Vascular Dilation in Patients With Early Diabetic Retinopathy From the EUROCONDOR.
    Invest Ophthalmol Vis Sci. 2019;60:2257-2262.
    PubMed     Abstract available


  69. MILLER WP, Toro AL, Barber AJ, Dennis MD, et al
    REDD1 Activates a ROS-Generating Feedback Loop in the Retina of Diabetic Mice.
    Invest Ophthalmol Vis Sci. 2019;60:2369-2379.
    PubMed     Abstract available


  70. DERVENIS N, Coleman AL, Harris A, Wilson MR, et al
    Factors Associated With Retinal Vessel Diameters in an Elderly Population: the Thessaloniki Eye Study.
    Invest Ophthalmol Vis Sci. 2019;60:2208-2217.
    PubMed     Abstract available


    April 2019
  71. FIGUERAS-ROCA M, Sala-Puigdollers A, Zarranz-Ventura J, Alba-Linero C, et al
    Anatomic Response to Intravitreal Dexamethasone Implant and Baseline Aqueous Humor Cytokine Levels in Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2019;60:1336-1343.
    PubMed     Abstract available


  72. BINOTTI WW, Romano AC
    Projection-Resolved Optical Coherence Tomography Angiography Parameters to Determine Severity in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:1321-1327.
    PubMed     Abstract available


  73. MORINO K, Murakami T, Dodo Y, Yasukura S, et al
    Characteristics of Diabetic Capillary Nonperfusion in Macular and Extramacular White Spots on Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2019;60:1595-1603.
    PubMed     Abstract available


  74. CUI RZ, Wang L, Qiao SN, Wang YC, et al
    ON-Type Retinal Ganglion Cells are Preferentially Affected in STZ-Induced Diabetic Mice.
    Invest Ophthalmol Vis Sci. 2019;60:1644-1656.
    PubMed     Abstract available


  75. LIU H, Tang J, Du Y, Saadane A, et al
    Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:1538-1546.
    PubMed     Abstract available


  76. HAN X, Kong J, Hartnett ME, Wang H, et al
    Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity.
    Invest Ophthalmol Vis Sci. 2019;60:1604-1613.
    PubMed     Abstract available


  77. BROWN EE, Ball JD, Chen Z, Khurshid GS, et al
    The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration.
    Invest Ophthalmol Vis Sci. 2019;60:1470-1477.
    PubMed     Abstract available


    March 2019
  78. ARCADU F, Benmansour F, Maunz A, Michon J, et al
    Deep Learning Predicts OCT Measures of Diabetic Macular Thickening From Color Fundus Photographs.
    Invest Ophthalmol Vis Sci. 2019;60:852-857.
    PubMed     Abstract available


  79. LI T, Jia Y, Wang S, Wang A, et al
    Retinal Microvascular Abnormalities in Children with Type 1 Diabetes Mellitus Without Visual Impairment or Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2019;60:990-998.
    PubMed     Abstract available


    February 2019
  80. CUI Y, Yang X, Zhang G, Guo H, et al
    Intraocular Pressure in General and Diabetic Populations From Southern China: the Dongguan Eye Study.
    Invest Ophthalmol Vis Sci. 2019;60:761-769.
    PubMed     Abstract available


  81. ESHAQ RS, Harris NR
    Loss of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) in the Diabetic Retina: Role of Matrix Metalloproteinases.
    Invest Ophthalmol Vis Sci. 2019;60:748-760.
    PubMed     Abstract available


  82. DMITRIEV AV, Henderson D, Linsenmeier RA
    Diabetes Alters pH Control in Rat Retina.
    Invest Ophthalmol Vis Sci. 2019;60:723-730.
    PubMed     Abstract available


  83. DEAK EA, Szalai E, Toth N, Malik RA, et al
    Longitudinal Changes in Corneal Cell and Nerve Fiber Morphology in Young Patients with Type 1 Diabetes with and without Diabetic Retinopathy: A 2-Year Follow-up Study.
    Invest Ophthalmol Vis Sci. 2019;60:830-837.
    PubMed     Abstract available


  84. SERGEYS J, Etienne I, Van Hove I, Lefevere E, et al
    Longitudinal In Vivo Characterization of the Streptozotocin-Induced Diabetic Mouse Model: Focus on Early Inner Retinal Responses.
    Invest Ophthalmol Vis Sci. 2019;60:807-822.
    PubMed     Abstract available


  85. YOSHITAKE T, Murakami T, Yoshitake S, Suzuma K, et al
    Anti-Fumarase Antibody as a Predictor of Functional Efficacy of Anti-VEGF Therapy for Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2019;60:787-794.
    PubMed     Abstract available


    January 2019
  86. HU J, Hu X, Kan T
    MiR-34c Participates in Diabetic Corneal Neuropathy Via Regulation of Autophagy.
    Invest Ophthalmol Vis Sci. 2019;60:16-25.
    PubMed     Abstract available


  87. ALAMRI AS, Brock JA, Herath CB, Rajapaksha IG, et al
    The Effects of Diabetes and High-Fat Diet on Polymodal Nociceptor and Cold Thermoreceptor Nerve Terminal Endings in the Corneal Epithelium.
    Invest Ophthalmol Vis Sci. 2019;60:209-217.
    PubMed     Abstract available


  88. ALLEN RS, Feola A, Motz CT, Ottensmeyer AL, et al
    Retinal Deficits Precede Cognitive and Motor Deficits in a Rat Model of Type II Diabetes.
    Invest Ophthalmol Vis Sci. 2019;60:123-133.
    PubMed     Abstract available


  89. MCANANY JJ, Park JC
    Cone Photoreceptor Dysfunction in Early-Stage Diabetic Retinopathy: Association Between the Activation Phase of Cone Phototransduction and the Flicker Electroretinogram.
    Invest Ophthalmol Vis Sci. 2019;60:64-72.
    PubMed     Abstract available


  90. ZHANG W, Wang Y, Kong Y
    Exosomes Derived From Mesenchymal Stem Cells Modulate miR-126 to Ameliorate Hyperglycemia-Induced Retinal Inflammation Via Targeting HMGB1.
    Invest Ophthalmol Vis Sci. 2019;60:294-303.
    PubMed     Abstract available


    December 2018
  91. HAFNER J, Salas M, Scholda C, Vogl WD, et al
    Dynamic Changes of Retinal Microaneurysms in Diabetes Imaged With In Vivo Adaptive Optics Optical Coherence Tomography.
    Invest Ophthalmol Vis Sci. 2018;59:5932-5940.
    PubMed     Abstract available


  92. OZAKI K, Terayama Y, Matsuura T
    Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes.
    Invest Ophthalmol Vis Sci. 2018;59:5868-5875.
    PubMed     Abstract available


  93. SONG B, Kim D, Nguyen NH, Roy S, et al
    Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:5965-5972.
    PubMed     Abstract available


  94. YASUKURA S, Murakami T, Suzuma K, Yoshitake T, et al
    Diabetic Nonperfused Areas in Macular and Extramacular Regions on Wide-Field Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2018;59:5893-5903.
    PubMed     Abstract available


    November 2018
  95. JOLTIKOV KA, Sesi CA, de Castro VM, Davila JR, et al
    Disorganization of Retinal Inner Layers (DRIL) and Neuroretinal Dysfunction in Early Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:5481-5486.
    PubMed     Abstract available


  96. LIM SW, Bandala-Sanchez E, Kolic M, Rogers SL, et al
    The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2018;59:5382-5390.
    PubMed     Abstract available


  97. LEE H, Chung H
    Author Response: Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2018;59:5367.
    PubMed    


  98. MIDENA E, Pilotto E, Bini S
    Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2018;59:5366.
    PubMed    


  99. LAMMER J, Karst SG, Lin MM, Cheney M, et al
    Association of Microaneurysms on Adaptive Optics Scanning Laser Ophthalmoscopy With Surrounding Neuroretinal Pathology and Visual Function in Diabetes.
    Invest Ophthalmol Vis Sci. 2018;59:5633-5640.
    PubMed     Abstract available


  100. YOU ZP, Zhang YL, Li BY, Zhu XG, et al
    Bioinformatics Analysis of Weighted Genes in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:5558-5563.
    PubMed     Abstract available


  101. FERDOUSI M, Petropoulos IN, Kalteniece A, Azmi S, et al
    No Relation Between the Severity of Corneal Nerve, Epithelial, and Keratocyte Cell Morphology With Measures of Dry Eye Disease in Type 1 Diabetes.
    Invest Ophthalmol Vis Sci. 2018;59:5525-5530.
    PubMed     Abstract available


    October 2018
  102. VUJOSEVIC S, Muraca A, Gatti V, Masoero L, et al
    Peripapillary Microvascular and Neural Changes in Diabetes Mellitus: An OCT-Angiography Study.
    Invest Ophthalmol Vis Sci. 2018;59:5074-5081.
    PubMed     Abstract available


  103. JIN G, Xiao W, Ding X, Xu X, et al
    Prevalence of and Risk Factors for Diabetic Retinopathy in a Rural Chinese Population: The Yangxi Eye Study.
    Invest Ophthalmol Vis Sci. 2018;59:5067-5073.
    PubMed     Abstract available


  104. MCANANY JJ, Park JC
    Temporal Frequency Abnormalities in Early-Stage Diabetic Retinopathy Assessed by Electroretinography.
    Invest Ophthalmol Vis Sci. 2018;59:4871-4879.
    PubMed     Abstract available


  105. DURAISAMY AJ, Mishra M, Kowluru A, Kowluru RA, et al
    Epigenetics and Regulation of Oxidative Stress in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:4831-4840.
    PubMed     Abstract available


    August 2018
  106. WANG N, Zou C, Zhao S, Wang Y, et al
    Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway.
    Invest Ophthalmol Vis Sci. 2018;59:4210-4217.
    PubMed     Abstract available


  107. ASHRAF M, Nesper PL, Jampol LM, Yu F, et al
    Statistical Model of Optical Coherence Tomography Angiography Parameters That Correlate With Severity of Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:4292-4298.
    PubMed     Abstract available


  108. NICHOLSON L, Crosby-Nwaobi R, Vasconcelos JC, Prevost AT, et al
    Mechanistic Evaluation of Panretinal Photocoagulation Versus Aflibercept in Proliferative Diabetic Retinopathy: CLARITY Substudy.
    Invest Ophthalmol Vis Sci. 2018;59:4277-4284.
    PubMed     Abstract available


    July 2018
  109. KALTENIECE A, Ferdousi M, Azmi S, Marshall A, et al
    Keratocyte Density Is Reduced and Related to Corneal Nerve Damage in Diabetic Neuropathy.
    Invest Ophthalmol Vis Sci. 2018;59:3584-3590.
    PubMed     Abstract available


    June 2018
  110. SANDHU HS, Eltanboly A, Shalaby A, Keynton RS, et al
    Automated Diagnosis and Grading of Diabetic Retinopathy Using Optical Coherence Tomography.
    Invest Ophthalmol Vis Sci. 2018;59:3155-3160.
    PubMed     Abstract available


    May 2018
  111. LU Y, Simonett JM, Wang J, Zhang M, et al
    Evaluation of Automatically Quantified Foveal Avascular Zone Metrics for Diagnosis of Diabetic Retinopathy Using Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2018;59:2212-2221.
    PubMed     Abstract available


  112. GALE JD, Berger B, Gilbert S, Popa S, et al
    A CCR2/5 Inhibitor, PF-04634817, Is Inferior to Monthly Ranibizumab in the Treatment of Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2018;59:2659-2669.
    PubMed     Abstract available


  113. MCANANY JJ, Park JC
    Reduced Contrast Sensitivity is Associated With Elevated Equivalent Intrinsic Noise in Type 2 Diabetics Who Have Mild or No Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:2652-2658.
    PubMed     Abstract available


  114. LIM RR, Grant DG, Olver TD, Padilla J, et al
    Young Ossabaw Pigs Fed a Western Diet Exhibit Early Signs of Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:2325-2338.
    PubMed     Abstract available


  115. SUNDSTROM JM, Hernandez C, Weber SR, Zhao Y, et al
    Proteomic Analysis of Early Diabetic Retinopathy Reveals Mediators of Neurodegenerative Brain Diseases.
    Invest Ophthalmol Vis Sci. 2018;59:2264-2274.
    PubMed     Abstract available


    April 2018
  116. CHEN Q, Tan F, Wu Y, Zhuang X, et al
    Characteristics of Retinal Structural and Microvascular Alterations in Early Type 2 Diabetic Patients.
    Invest Ophthalmol Vis Sci. 2018;59:2110-2118.
    PubMed     Abstract available


  117. NAHOMI RB, Sampathkumar S, Myers AM, Elghazi L, et al
    The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice.
    Invest Ophthalmol Vis Sci. 2018;59:2042-2053.
    PubMed     Abstract available


  118. LEI J, Yi E, Suo Y, Chen C, et al
    Distinctive Analysis of Macular Superficial Capillaries and Large Vessels Using Optical Coherence Tomographic Angiography in Healthy and Diabetic Eyes.
    Invest Ophthalmol Vis Sci. 2018;59:1937-1943.
    PubMed     Abstract available


  119. LUO XY, Tan NYQ, Chee ML, Shi Y, et al
    Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study.
    Invest Ophthalmol Vis Sci. 2018;59:2205-2211.
    PubMed     Abstract available


  120. ONISHI AC, Nesper PL, Roberts PK, Moharram GA, et al
    Importance of Considering the Middle Capillary Plexus on OCT Angiography in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:2167-2176.
    PubMed     Abstract available


    March 2018
  121. SCHORI C, Trachsel C, Grossmann J, Zygoula I, et al
    The Proteomic Landscape in the Vitreous of Patients With Age-Related and Diabetic Retinal Disease.
    Invest Ophthalmol Vis Sci. 2018;59:AMD31-AMD40.
    PubMed     Abstract available


  122. GLASSMAN AR, Liu D, Jampol LM, Sun JK, et al
    Changes in Blood Pressure and Urine Albumin-Creatinine Ratio in a Randomized Clinical Trial Comparing Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2018;59:1199-1205.
    PubMed     Abstract available


    February 2018
  123. DELIYANTI D, Alrashdi SF, Tan SM, Meyer C, et al
    Nrf2 Activation Is a Potential Therapeutic Approach to Attenuate Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:815-825.
    PubMed     Abstract available


  124. LEE H, Jang H, Choi YA, Kim HC, et al
    Association Between Soluble CD14 in the Aqueous Humor and Hyperreflective Foci on Optical Coherence Tomography in Patients With Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2018;59:715-721.
    PubMed     Abstract available


  125. CHEN H, Zhang X, Liao N, Mi L, et al
    Enhanced Expression of NLRP3 Inflammasome-Related Inflammation in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2018;59:978-985.
    PubMed     Abstract available


  126. CHEN X, Graham J, Petropoulos IN, Ponirakis G, et al
    Corneal Nerve Fractal Dimension: A Novel Corneal Nerve Metric for the Diagnosis of Diabetic Sensorimotor Polyneuropathy.
    Invest Ophthalmol Vis Sci. 2018;59:1113-1118.
    PubMed     Abstract available


    January 2018
  127. WHITCUP SM, Cidlowski JA, Csaky KG, Ambati J, et al
    Pharmacology of Corticosteroids for Diabetic Macular Edema.
    Invest Ophthalmol Vis Sci. 2018;59:1-12.
    PubMed     Abstract available


  128. KIM MK, Aung MH, Mees L, Olson DE, et al
    Dopamine Deficiency Mediates Early Rod-Driven Inner Retinal Dysfunction in Diabetic Mice.
    Invest Ophthalmol Vis Sci. 2018;59:572-581.
    PubMed     Abstract available


  129. ABRAMOFF MD, Fort PE, Han IC, Jayasundera KT, et al
    Approach for a Clinically Useful Comprehensive Classification of Vascular and Neural Aspects of Diabetic Retinal Disease.
    Invest Ophthalmol Vis Sci. 2018;59:519-527.
    PubMed     Abstract available


    December 2017
  130. STUARD WL, Titone R, Robertson DM
    Tear Levels of Insulin-Like Growth Factor Binding Protein 3 Correlate With Subbasal Nerve Plexus Changes in Patients With Type 2 Diabetes Mellitus.
    Invest Ophthalmol Vis Sci. 2017;58:6105-6112.
    PubMed     Abstract available


  131. LAGALI NS, Allgeier S, Guimaraes P, Badian RA, et al
    Reduced Corneal Nerve Fiber Density in Type 2 Diabetes by Wide-Area Mosaic Analysis.
    Invest Ophthalmol Vis Sci. 2017;58:6318-6327.
    PubMed     Abstract available


  132. GUYON B, Elphege E, Flores M, Gauthier AS, et al
    Retinal Reflectivity Measurement for Cone Impairment Estimation and Visual Assessment After Diabetic Macular Edema Resolution (RECOVER-DME).
    Invest Ophthalmol Vis Sci. 2017;58:6241-6247.
    PubMed     Abstract available


  133. DURAISAMY AJ, Mishra M, Kowluru RA
    Crosstalk Between Histone and DNA Methylation in Regulation of Retinal Matrix Metalloproteinase-9 in Diabetes.
    Invest Ophthalmol Vis Sci. 2017;58:6440-6448.
    PubMed     Abstract available


  134. FENWICK EK, Khadka J, Pesudovs K, Rees G, et al
    Diabetic Retinopathy and Macular Edema Quality-of-Life Item Banks: Development and Initial Evaluation Using Computerized Adaptive Testing.
    Invest Ophthalmol Vis Sci. 2017;58:6379-6387.
    PubMed     Abstract available


  135. SRINIVASAN S, Dehghani C, Pritchard N, Edwards K, et al
    Corneal and Retinal Neuronal Degeneration in Early Stages of Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2017;58:6365-6373.
    PubMed     Abstract available


  136. ZHANG SJ, Chen X, Li CP, Li XM, et al
    Identification and Characterization of Circular RNAs as a New Class of Putative Biomarkers in Diabetes Retinopathy.
    Invest Ophthalmol Vis Sci. 2017;58:6500-6509.
    PubMed     Abstract available


  137. MITCHELL SL, Neininger AC, Bruce CN, Chocron IM, et al
    Mitochondrial Haplogroups Modify the Effect of Diabetes Duration and HbA1c on Proliferative Diabetic Retinopathy Risk in Patients With Type 2 Diabetes.
    Invest Ophthalmol Vis Sci. 2017;58:6481-6488.
    PubMed     Abstract available


    November 2017
  138. WEI Q, Zhang T, Jiang R, Chang Q, et al
    Vitreous Fibronectin and Fibrinogen Expression Increased in Eyes With Proliferative Diabetic Retinopathy After Intravitreal Anti-VEGF Therapy.
    Invest Ophthalmol Vis Sci. 2017;58:5783-5791.
    PubMed     Abstract available


  139. DODO Y, Murakami T, Suzuma K, Yoshitake S, et al
    Diabetic Neuroglial Changes in the Superficial and Deep Nonperfused Areas on Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2017;58:5870-5879.
    PubMed     Abstract available


  140. SRINIVASAN S, Raman R, Swaminathan G, Ganesan S, et al
    Incidence, Progression, and Risk Factors for Cataract in Type 2 Diabetes.
    Invest Ophthalmol Vis Sci. 2017;58:5921-5929.
    PubMed     Abstract available


  141. HWANG HS, Chae JB, Kim JY, Kim DY, et al
    Association Between Hyperreflective Dots on Spectral-Domain Optical Coherence Tomography in Macular Edema and Response to Treatment.
    Invest Ophthalmol Vis Sci. 2017;58:5958-5967.
    PubMed     Abstract available


    October 2017
  142. OMAE T, Nagaoka T, Yoshida A
    Effect of Circulating Omentin-1 on the Retinal Circulation in Patients With Type 2 Diabetes Mellitus.
    Invest Ophthalmol Vis Sci. 2017;58:5086-5092.
    PubMed     Abstract available


  143. HU P, Hunt NH, Arfuso F, Shaw LC, et al
    Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Muller Cells of Diabetic Human and Rodent Retina.
    Invest Ophthalmol Vis Sci. 2017;58:5043-5055.
    PubMed     Abstract available


  144. DENG G, Moran EP, Cheng R, Matlock G, et al
    Therapeutic Effects of a Novel Agonist of Peroxisome Proliferator-Activated Receptor Alpha for the Treatment of Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2017;58:5030-5042.
    PubMed     Abstract available


  145. BOSS JD, Singh PK, Pandya HK, Tosi J, et al
    Assessment of Neurotrophins and Inflammatory Mediators in Vitreous of Patients With Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2017;58:5594-5603.
    PubMed     Abstract available


  146. BLAIR NP, Wanek J, Felder AE, Joslin CE, et al
    Retinal Oximetry and Vessel Diameter Measurements With a Commercially Available Scanning Laser Ophthalmoscope in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2017;58:5556-5563.
    PubMed     Abstract available


  147. HAFNER J, Ginner L, Karst S, Leitgeb R, et al
    Regional Patterns of Retinal Oxygen Saturation and Microvascular Hemodynamic Parameters Preceding Retinopathy in Patients With Type II Diabetes.
    Invest Ophthalmol Vis Sci. 2017;58:5541-5547.
    PubMed     Abstract available


    September 2017
  148. DI G, Qi X, Zhao X, Zhang S, et al
    Corneal Epithelium-Derived Neurotrophic Factors Promote Nerve Regeneration.
    Invest Ophthalmol Vis Sci. 2017;58:4695-4702.
    PubMed     Abstract available


  149. FERNANDEZ-BUENO I, Jones R, Soriano-Romani L, Lopez-Garcia A, et al
    Histologic Characterization of Retina Neuroglia Modifications in Diabetic Zucker Diabetic Fatty Rats.
    Invest Ophthalmol Vis Sci. 2017;58:4925-4933.
    PubMed     Abstract available


  150. KAIZU Y, Nakao S, Yoshida S, Hayami T, et al
    Optical Coherence Tomography Angiography Reveals Spatial Bias of Macular Capillary Dropout in Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2017;58:4889-4897.
    PubMed     Abstract available


  151. BRAZIER J, Muston D, Konwea H, Power GS, et al
    Evaluating the Relationship Between Visual Acuity and Utilities in Patients With Diabetic Macular Edema Enrolled in Intravitreal Aflibercept Studies.
    Invest Ophthalmol Vis Sci. 2017;58:4818-4825.
    PubMed     Abstract available


    May 2017
  152. JOLTIKOV KA, de Castro VM, Davila JR, Anand R, et al
    Multidimensional Functional and Structural Evaluation Reveals Neuroretinal Impairment in Early Diabetic Retinopathy.
    Invest Ophthalmol Vis Sci. 2017;58:BIO277-BIO290.
    PubMed     Abstract available


  153. NESPER PL, Roberts PK, Onishi AC, Chai H, et al
    Quantifying Microvascular Abnormalities With Increasing Severity of Diabetic Retinopathy Using Optical Coherence Tomography Angiography.
    Invest Ophthalmol Vis Sci. 2017;58:BIO307-BIO315.
    PubMed     Abstract available


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