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Diabetes

Free Subscription Articles published in Metabolism Retrieve available abstracts of 78 articles: HTML format

Single Articles

June 2026
1. BAILEY CJ, Gwilt M, Brand KMG
   Metformin: Antidiabetic actions from cells to tissues.
   Metabolism. 2026;179:156589.
   PubMed     Abstract available
   
   
   
2. ZHANG H, Chen QF, Lip GYH, Tilg H, et al
   Burden of metabolic diseases, 1990-2023, with forecasts to 2030 for the Asia-Pacific region.
   Metabolism. 2026;179:156575.
   PubMed     Abstract available
   
   
   May 2026
3. ZHANG H, Yue T, Wang S, Shi J, et al
   A multi-omics atlas of multisystem complications in type 2 diabetes reveals molecular signatures and improves risk prediction.
   Metabolism. 2026 May 20:156650. doi: 10.1016/j.metabol.2026.156650.
   PubMed     Abstract available
   
   
   
4. GARCIA-GAVILAN JF, Paz-Graniel I, Salas-Salvado J
   Reply to letter to the editor: Metabolomic signatures of type 2 diabetes and mortality: Methodological considerations and unresolved questions.
   Metabolism. 2026 May 18:156649. doi: 10.1016/j.metabol.2026.156649.
   PubMed    
   
   
   
5. LIU J, Xu W, Yan W, Qin Y, et al
   Islet inflammatory macrophages drive MSC loss and multiple interactions involved in beta-cell adaptation during diabetes.
   Metabolism. 2026;181:156636.
   PubMed     Abstract available
   
   
   
6. YAMAZAKI H, Tokgoz S, Tauchi S, Nakamura F, et al
   Structural determinants of beta-cell failure in type 2 diabetes: a multimodality imaging study.
   Metabolism. 2026 May 13:156631. doi: 10.1016/j.metabol.2026.156631.
   PubMed     Abstract available
   
   
   
7. HAN J
   Metabolomic signatures of type 2 diabetes and mortality: Methodological considerations and unresolved questions.
   Metabolism. 2026 May 7:156627. doi: 10.1016/j.metabol.2026.156627.
   PubMed    
   
   
   
8. GIOSUE A, Skantze V, Testa R, D'Abbronzo G, et al
   Postprandial glucose profiles may reflect heterogeneity in insulin secretion and sensitivity in type 2 diabetes.
   Metabolism. 2026;181:156626.
   PubMed     Abstract available
   
   
   
9. ATABAKI NN, Coral DE, Pomares-Millan H, Smith K, et al
   A biological-systems-based analysis using proteomic and metabolic network inference reveals mechanistic insights into hepatic steatosis.
   Metabolism. 2026;178:156552.
   PubMed     Abstract available
   
   
   April 2026
10. JIANG M, An X
    6-Phosphofructokinase-2/fructose-2,6-bisphosphatase 3: A potential target in the development of diabetes and its complications.
    Metabolism. 2026 Apr 14:156621. doi: 10.1016/j.metabol.2026.156621.
    PubMed     Abstract available
    
    
    
11. MUZUROVIC E, Katsiki N, Volcansek S, Plescia F, et al
    Emerging incretin- and multi-agonist-based treatments - the continued refinement and continuous expansion of a potent therapeutic armamentarium for cardio-kidney-liver-metabolic diseases and beyond.
    Metabolism. 2026;177:156494.
    PubMed     Abstract available
    
    
    
12. PANUNZI S, Russo S, Pompa M, De Gaetano A, et al
    Personalizing bariatric metabolic surgery: Predictors of weight-loss success and risk of weight recurrence.
    Metabolism. 2026;177:156495.
    PubMed     Abstract available
    
    
    March 2026
13. SONG W, Nie X, Zhu Z, Wang Q, et al
    Proteomics and metabolomics biomarkers for predicting the onset and progression of diabetic complications: A systematic review and bioinformatics integration.
    Metabolism. 2026 Mar 25:156601. doi: 10.1016/j.metabol.2026.156601.
    PubMed     Abstract available
    
    
    
14. GARCIA-GAVILAN JF, Paz-Graniel I, Perez-Acosta JA, Ruiz-Canela M, et al
    Metabolomics profiles of type 2 diabetes and insulin resistance and their associations with total mortality. T2D metabolites linked to mortality.
    Metabolism. 2026 Mar 23:156599. doi: 10.1016/j.metabol.2026.156599.
    PubMed     Abstract available
    
    
    
15. CHEN L, Dong X, Zhang Q, Wang H, et al
    Once-weekly insulin GZR4 versus once-daily insulin degludec in Chinese people with type 2 diabetes: A multicenter, open-label, randomized, phase 2 trial.
    Metabolism. 2026;179:156592.
    PubMed     Abstract available
    
    
    
16. KHADIVI Y, Tavallaeinejad P, Hashemipour M, Khachikian A, et al
    Mapping circulating microRNA signatures in type 1 diabetic microvascular disease: A systematic review and Bayesian multilevel meta-analysis with bioinformatic integration of molecular dysregulation.
    Metabolism. 2026 Mar 13:156591. doi: 10.1016/j.metabol.2026.156591.
    PubMed     Abstract available
    
    
    
17. GIUSTINA A, di Filippo L, Aleksova A, Bollerslev J, et al
    Consensus statement on vitamin D role in metabolic health.
    Metabolism. 2026;176:156484.
    PubMed     Abstract available
    
    
    February 2026
18. LEE DY, Lee JB, Jung I, Park SY, et al
    Association of daytime circadian-aligned activity with glycemic control in type 2 diabetes: Insights from continuous glucose monitoring and wearable data.
    Metabolism. 2026;179:156570.
    PubMed     Abstract available
    
    
    
19. AMREIN K, Kim SH, Brath H, Fasching P, et al
    Mini-review. Vitamin D for the prevention of type 2 diabetes: Evidence and implications.
    Metabolism. 2026 Feb 16:156566. doi: 10.1016/j.metabol.2026.156566.
    PubMed     Abstract available
    
    
    
20. LIU P, Shen N, Zhou Y, Wu J, et al
    PFKFB3 nuclear translocation improves diabetic retinopathy by attenuating endothelial cell senescence through inhibition of USP7-p53 axis.
    Metabolism. 2026;178:156553.
    PubMed     Abstract available
    
    
    
21. ZHU R, Guo J, Huttunen-Lenz M, Stratton G, et al
    Enduring improvements in hepatic insulin sensitivity predict sustained remission of prediabetes during a 3-year lifestyle intervention: results from the PREVIEW multinational diabetes prevention trial.
    Metabolism. 2026;178:156546.
    PubMed     Abstract available
    
    
    
22. ZHANG J, Guan X, Kong M, Xia M, et al
    GLP-1RAs and tirzepatide may reduce heart failure risk in obese but not in non-obese patients with cardiovascular or renal disease: A systematic review and meta-analysis.
    Metabolism. 2026;175:156433.
    PubMed     Abstract available
    
    
    January 2026
23. LIN Z, Lv D, Zha H, Liu H, et al
    HMGCS2 desuccinylation modulates acetoacetate to drive tubule-macrophage inflammatory crosstalk in diabetic kidney disease.
    Metabolism. 2026;177:156510.
    PubMed     Abstract available
    
    
    
24. LEANZA G, Faraj M, Cannata F, Viola V, et al
    Bone inflammation in postmenopausal women with type 2 diabetes or obesity in relation to Wnt signaling and bone strength.
    Metabolism. 2026 Jan 8:156492. doi: 10.1016/j.metabol.2026.156492.
    PubMed     Abstract available
    
    
    
25. GERLACH PA, Gadgaard S, Madsen JS, Lindquist P, et al
    Global glucagon-like peptide-2 receptor activation linked to increased obesity risk in the UK Biobank.
    Metabolism. 2026 Jan 8:156489. doi: 10.1016/j.metabol.2025.156489.
    PubMed     Abstract available
    
    
    
26. MUNOZ F, Gao Q, Mattanovich M, Trost K, et al
    Lysine potentiates insulin secretion via AASS-dependent catabolism and regulation of GABA content and signaling.
    Metabolism. 2026;174:156423.
    PubMed     Abstract available
    
    
    December 2025
27. D'ADDIO F, Bucciarelli L, Lunati ME, Fiorina P, et al
    Metabolic and immune dysfunction at the crossroads between type 1 diabetes and neurodegeneration.
    Metabolism. 2025 Dec 17:156471. doi: 10.1016/j.metabol.2025.156471.
    PubMed     Abstract available
    
    
    
28. YANG J, Yang X, Zheng Y, Wang A, et al
    27-Hydroxycholesterol exacerbates hepatic insulin resistance via plasma membrane cholesterol remodeling.
    Metabolism. 2025;173:156392.
    PubMed     Abstract available
    
    
    November 2025
29. JINYI L, Xianguang D, Yuhan D, Haoyue H, et al
    Metabolic reprogramming in diabetic foot ulcers: mechanisms, therapeutic implications and future perspectives.
    Metabolism. 2025;175:156455.
    PubMed     Abstract available
    
    
    
30. WANG Y, Sandforth A, von Schwartzenberg RJ, Ganslmeier M, et al
    Lifestyle intervention is more effective in high 1-hour post-load glucose than in prediabetes for restoring beta-cell function, reducing ectopic fat, and preventing type 2 diabetes.
    Metabolism. 2025 Nov 3:156430. doi: 10.1016/j.metabol.2025.156430.
    PubMed     Abstract available
    
    
    
31. STUBBENDORFF A, Janzi S, Jukkola J, Morency M, et al
    Mini-review of the EAT-Lancet planetary health diet and its role in cardiometabolic disease prevention.
    Metabolism. 2025;172:156373.
    PubMed     Abstract available
    
    
    October 2025
32. PAN L, He Y, Xiang Y, Mao B, et al
    Angiopoietin-like protein 8 mediates inflammation and fibrosis of tubular cells in diabetic kidney disease progression by interacting with Akt2.
    Metabolism. 2025 Oct 17:156418. doi: 10.1016/j.metabol.2025.156418.
    PubMed     Abstract available
    
    
    
33. ASHLAW EF, Elfers CT, Chichura KS, Miranda IC, et al
    A melanocortin 4- and glucagon-like peptide 1 receptor multiple agonist for the treatment of diabetes and obesity.
    Metabolism. 2025 Oct 13:156414. doi: 10.1016/j.metabol.2025.156414.
    PubMed     Abstract available
    
    
    
34. MISHRA RC, Mallat RK, John CM, Belke D, et al
    Administration of the K(Ca) channel activator SKA-31 improves long-term endothelial function, blood pressure regulation and cardiac performance in rats with type 2 diabetes.
    Metabolism. 2025 Oct 1:156410. doi: 10.1016/j.metabol.2025.156410.
    PubMed     Abstract available
    
    
    August 2025
35. HENDLINGER M, Mastrototaro L, Exterkate M, Apostolopoulou M, et al
    Exercise training increases skeletal muscle sphingomyelinases and affects mitochondrial quality control in men with type 2 diabetes.
    Metabolism. 2025 Aug 2:156361. doi: 10.1016/j.metabol.2025.156361.
    PubMed     Abstract available
    
    
    
36. HAKIM JP, Handelsman Y, Banerjee T
    Use of finerenone in patients with chronic kidney disease at high risk of heart failure.
    Metabolism. 2025;169:156297.
    PubMed     Abstract available
    
    
    
37. HUANG H, Ruan H, Lu X, Chen S, et al
    Comprehensive assessment of the causal effects and metabolite mediators of glucose-lowering drug targets on cardio-renal-liver-metabolic health.
    Metabolism. 2025;169:156276.
    PubMed     Abstract available
    
    
    July 2025
38. LIANG T, Jiang T, Liang Z, Chen Y, et al
    Lactiplantibacillus plantarum strain 84-3-derived l-glutamine ameliorates glucose homeostasis via AMPK/PPARgamma signaling pathway activation in type 2 diabetes.
    Metabolism. 2025;172:156357.
    PubMed     Abstract available
    
    
    
39. ZHANG H, Wang W, Liu P, Zhang T, et al
    Flot2 protects against podocyte injury by maintaining the stability of synaptopodin in diabetic nephropathy.
    Metabolism. 2025;171:156354.
    PubMed     Abstract available
    
    
    
40. GUO C, Li J, Yang X, Xie W, et al
    AEBP1 as a promising therapeutic target for skeletal muscle insulin resistance in type 2 diabetes mellitus: Convergent evidence from Mendelian randomization and functional validation.
    Metabolism. 2025 Jul 4:156339. doi: 10.1016/j.metabol.2025.156339.
    PubMed     Abstract available
    
    
    June 2025
41. SU JB, Chen G, Sun QY, Fu X, et al
    USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice.
    Metabolism. 2025;170:156326.
    PubMed     Abstract available
    
    
    May 2025
42. GALAN A, Garcia-Garcia F
    Revisiting gender differences in obesity and type 2 diabetes: Response letter.
    Metabolism. 2025 May 29:156307. doi: 10.1016/j.metabol.2025.156307.
    PubMed    
    
    
    
43. WANG P, Zhang Y, Giovannucci EL
    Dietary context in the association between red meat consumption and risk of type 2 diabetes.
    Metabolism. 2025;169:156277.
    PubMed     Abstract available
    
    
    April 2025
44. WU H, Yang Z, Zhou T, Wang J, et al
    UBC9 ameliorates diabetic cardiomyopathy by modulating cardiomyocyte mitophagy through NEDD4/RUNX2/PSEN2 axis.
    Metabolism. 2025 Apr 8:156264. doi: 10.1016/j.metabol.2025.156264.
    PubMed     Abstract available
    
    
    
45. ZHONG Y, Wei J, Jiang R
    Revisiting gender differences in obesity and type 2 diabetes: Letter to the editor.
    Metabolism. 2025 Apr 3:156260. doi: 10.1016/j.metabol.2025.156260.
    PubMed    
    
    
    March 2025
46. MOLDOVAN RA, Hidalgo MR, Castane H, Jimenez-Franco A, et al
    Landscape of sex differences in obesity and type 2 diabetes in subcutaneous adipose tissue: a systematic review and meta-analysis of transcriptomics studies.
    Metabolism. 2025 Mar 27:156241. doi: 10.1016/j.metabol.2025.156241.
    PubMed     Abstract available
    
    
    
47. BHOWMICK DC, Ahn M, Bhattacharya S, Aslamy A, et al
    DOC2b enrichment mitigates proinflammatory cytokine-induced CXCL10 expression by attenuating IKKbeta and STAT-1 signaling in human islets.
    Metabolism. 2025;164:156132.
    PubMed     Abstract available
    
    
    
48. KARAKASIS P, Patoulias D, Fragakis N, Mantzoros CS, et al
    Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition: Systematic review and network meta-analysis.
    Metabolism. 2025;164:156113.
    PubMed     Abstract available
    
    
    February 2025
49. SCHORK A, Fritsche A, Schleicher ED, Peter A, et al
    Differential risk assessment in persons at risk of type 2 diabetes using urinary peptidomics.
    Metabolism. 2025;167:156174.
    PubMed     Abstract available
    
    
    
50. HUANG J
    A systematic review & updated meta-analysis on the association between higher consumption of ultra processed foods and risk of diabetes and its complications: Letter to the editor.
    Metabolism. 2025 Feb 11:156156. doi: 10.1016/j.metabol.2025.156156.
    PubMed    
    
    
    
51. SOUZA M, Moura FS, Lima LCV, Amaral MJM, et al
    A systematic review & updated meta-analysis on the association between higher consumption of ultra processed foods and risk of diabetes and its complications: Response letter.
    Metabolism. 2025 Feb 11:156155. doi: 10.1016/j.metabol.2025.156155.
    PubMed    
    
    
    
52. CHEN J, Luo M, Xing Z, Chen Y, et al
    Start small, think big: MicroRNAs in diabetes mellitus and relevant cardiorenal-liver metabolic health spectrum.
    Metabolism. 2025 Feb 4:156153. doi: 10.1016/j.metabol.2025.156153.
    PubMed     Abstract available
    
    
    
53. MEZZA T, Wewer Albrechtsen NJ, Di Giuseppe G, Ferraro PM, et al
    Human subjects with impaired beta-cell function and glucose tolerance have higher levels of intra-islet intact GLP-1.
    Metabolism. 2025;163:156087.
    PubMed     Abstract available
    
    
    
54. KOKKORAKIS M, Folkertsma P, Forte JC, Wolffenbuttel BHR, et al
    GDF-15 improves the predictive capacity of steatotic liver disease non-invasive tests for incident morbidity and mortality risk for cardio-renal-metabolic diseases and malignancies.
    Metabolism. 2025;163:156047.
    PubMed     Abstract available
    
    
    January 2025
55. SOUZA M, Moura FS, Lima LCV, Amaral MJM, et al
    Association between higher consumption of ultra-processed foods and risk of diabetes and its complications: A systematic review & updated meta-analysis.
    Metabolism. 2025 Jan 21:156134. doi: 10.1016/j.metabol.2025.156134.
    PubMed     Abstract available
    
    
    
56. LUO YY, Ruan CS, Zhao FZ, Yang M, et al
    ZBED3 exacerbates hyperglycemia by promoting hepatic gluconeogenesis through CREB signaling.
    Metabolism. 2025;162:156049.
    PubMed     Abstract available
    
    
    
57. DENG X, Tang C, Fang T, Li T, et al
    Disruption of branched-chain amino acid homeostasis promotes the progression of DKD via enhancing inflammation and fibrosis-associated epithelial-mesenchymal transition.
    Metabolism. 2025;162:156037.
    PubMed     Abstract available
    
    
    December 2024
58. DOU C, Liu D, Kong L, Chen M, et al
    Shared genetic architecture of type 2 diabetes with muscle mass and function and frailty reveals comorbidity etiology and pleiotropic druggable targets.
    Metabolism. 2024 Dec 20:156112. doi: 10.1016/j.metabol.2024.156112.
    PubMed     Abstract available
    
    
    
59. KIM JS, Jun JH, Lee J, Park S, et al
    HDAC6 mediates NLRP3 inflammasome activation in the pathogenesis of diabetic retinopathy.
    Metabolism. 2024 Dec 15:156108. doi: 10.1016/j.metabol.2024.156108.
    PubMed     Abstract available
    
    
    November 2024
60. WU Q, Zeng Y, Geng K, Guo M, et al
    The role of IL-1 family cytokines in diabetic cardiomyopathy.
    Metabolism. 2024 Nov 25:156083. doi: 10.1016/j.metabol.2024.156083.
    PubMed     Abstract available
    
    
    
61. CONGUR I, Mingrone G, Guan K
    Targeting endoplasmic reticulum stress as a potential therapeutic strategy for diabetic cardiomyopathy.
    Metabolism. 2024 Nov 6:156062. doi: 10.1016/j.metabol.2024.156062.
    PubMed     Abstract available
    
    
    
62. ZHANG H, Zhou XD, Shapiro MD, Lip GYH, et al
    Global burden of metabolic diseases, 1990-2021.
    Metabolism. 2024;160:155999.
    PubMed     Abstract available
    
    
    August 2024
63. MISHRA RC, Belke DD, Singh L, Wulff H, et al
    Targeting endothelial K(Ca) channels in vivo restores arterial and endothelial function in type 2 diabetic rats.
    Metabolism. 2024 Aug 18:156001. doi: 10.1016/j.metabol.2024.156001.
    PubMed     Abstract available
    
    
    
64. ROSELL-DIAZ M, Petit-Gay A, Molas-Prat C, Gallardo-Nuell L, et al
    Metformin-induced changes in the gut microbiome and plasma metabolome are associated with cognition in men.
    Metabolism. 2024;157:155941.
    PubMed     Abstract available
    
    
    
65. CAI Z, Yang Y, Zhong J, Ji Y, et al
    cGAS suppresses beta-cell proliferation by a STING-independent but CEBPbeta-dependent mechanism.
    Metabolism. 2024;157:155933.
    PubMed     Abstract available
    
    
    July 2024
66. KANG JS, Cho NJ, Lee SW, Lee JG, et al
    RIPK3 causes mitochondrial dysfunction and albuminuria in diabetic podocytopathy through PGAM5-Drp1 signaling.
    Metabolism. 2024 Jul 30:155982. doi: 10.1016/j.metabol.2024.155982.
    PubMed     Abstract available
    
    
    
67. SHU S, Cui H, Liu Z, Zhang H, et al
    Suppression of RCAN1 alleviated lipid accumulation and mitochondrial fission in diabetic cardiomyopathy.
    Metabolism. 2024 Jul 23:155977. doi: 10.1016/j.metabol.2024.155977.
    PubMed     Abstract available
    
    
    
68. ZHAO M, Shen Z, Zheng Z, Xu Y, et al
    Cardiomyocyte LGR6 alleviates ferroptosis in diabetic cardiomyopathy via regulating mitochondrial biogenesis.
    Metabolism. 2024 Jul 20:155979. doi: 10.1016/j.metabol.2024.155979.
    PubMed     Abstract available
    
    
    
69. RICHTER MM, Kemp IM, Heeboll S, Winther-Sorensen M, et al
    Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms.
    Metabolism. 2024;156:155915.
    PubMed     Abstract available
    
    
    June 2024
70. HANDELSMAN Y, Anderson JE, Bakris GL, Ballantyne CM, et al
    DCRM 2.0: Multispecialty practice recommendations for the management of diabetes, cardiorenal, and metabolic diseases.
    Metabolism. 2024 Jun 4:155931. doi: 10.1016/j.metabol.2024.155931.
    PubMed     Abstract available
    
    
    
71. SABATINI S, Nolan JJ, O'Donoghue G, Kennedy A, et al
    Baseline phenotypes with preserved beta-cell function and high insulin concentrations have the best improvements in glucose tolerance after weight loss: results from the prospective DEXLIFE and EGIR-RISC studies.
    Metabolism. 2024;155:155910.
    PubMed     Abstract available
    
    
    May 2024
72. HUTTASCH M, Roden M, Kahl S
    Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease?
    Metabolism. 2024 May 21:155937. doi: 10.1016/j.metabol.2024.155937.
    PubMed     Abstract available
    
    
    
73. LIAN LY, Targher G, Byrne CD, Liu WY, et al
    Resmetirom for MASH patients with diabetes: challenges and opportunities in the real world.
    Metabolism. 2024 May 15:155935. doi: 10.1016/j.metabol.2024.155935.
    PubMed    
    
    
    April 2024
74. JEREMIAH SS, Moin ASM, Butler AE
    Virus-induced diabetes mellitus, revisiting infection etiology in light of SARS-CoV-2.
    Metabolism. 2024 Apr 18:155917. doi: 10.1016/j.metabol.2024.155917.
    PubMed     Abstract available
    
    
    
75. ROSENDO-SILVA D, Gomes PB, Rodrigues T, Viana S, et al
    Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction.
    Metabolism. 2024;153:155788.
    PubMed     Abstract available
    
    
    March 2024
76. HE Y, Qu L
    The role and mechanisms of non-coding RNAs in diabetic peripheral neuropathy.
    Metabolism. 2024 Mar 8:155833. doi: 10.1016/j.metabol.2024.155833.
    PubMed     Abstract available
    
    
    November 2023
77. ALABDULJABBAR K, le Roux CW
    Pharmacotherapy before and after bariatric surgery.
    Metabolism. 2023;148:155692.
    PubMed     Abstract available
    
    
    
78. SONG E, Hwang SY, Park MJ, Jang A, et al
    Additive impact of diabetes and sarcopenia on all-cause and cardiovascular mortality: A longitudinal nationwide population-based study.
    Metabolism. 2023;148:155678.
    PubMed     Abstract available
    
    

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