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Articles published in Metabolism

Retrieve available abstracts of 62 articles:
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Single Articles


    April 2026
  1. MUZUROVIC E, Katsiki N, Volcansek S, Plescia F, et al
    Emerging incretin- and multi-agonist-based treatments - the continued refinement and continuous expansion of a potent therapeutic armamentarium for cardio-kidney-liver-metabolic diseases and beyond.
    Metabolism. 2026;177:156494.
    PubMed     Abstract available


  2. PANUNZI S, Russo S, Pompa M, De Gaetano A, et al
    Personalizing bariatric metabolic surgery: Predictors of weight-loss success and risk of weight recurrence.
    Metabolism. 2026;177:156495.
    PubMed     Abstract available


    March 2026
  3. GIUSTINA A, di Filippo L, Aleksova A, Bollerslev J, et al
    Consensus statement on vitamin D role in metabolic health.
    Metabolism. 2026;176:156484.
    PubMed     Abstract available


    February 2026
  4. LEE DY, Lee JB, Jung I, Park SY, et al
    Association of daytime circadian-aligned activity with glycemic control in type 2 diabetes: Insights from continuous glucose monitoring and wearable data.
    Metabolism. 2026;179:156570.
    PubMed     Abstract available


  5. AMREIN K, Kim SH, Brath H, Fasching P, et al
    Mini-review. Vitamin D for the prevention of type 2 diabetes: Evidence and implications.
    Metabolism. 2026 Feb 16:156566. doi: 10.1016/j.metabol.2026.156566.
    PubMed     Abstract available


  6. LIU P, Shen N, Zhou Y, Wu J, et al
    PFKFB3 nuclear translocation improves diabetic retinopathy by attenuating endothelial cell senescence through inhibition of USP7-p53 axis.
    Metabolism. 2026;178:156553.
    PubMed     Abstract available


  7. ZHU R, Guo J, Huttunen-Lenz M, Stratton G, et al
    Enduring improvements in hepatic insulin sensitivity predict sustained remission of prediabetes during a 3-year lifestyle intervention: results from the PREVIEW multinational diabetes prevention trial.
    Metabolism. 2026;178:156546.
    PubMed     Abstract available


  8. ZHANG J, Guan X, Kong M, Xia M, et al
    GLP-1RAs and tirzepatide may reduce heart failure risk in obese but not in non-obese patients with cardiovascular or renal disease: A systematic review and meta-analysis.
    Metabolism. 2026;175:156433.
    PubMed     Abstract available


    January 2026
  9. LIN Z, Lv D, Zha H, Liu H, et al
    HMGCS2 desuccinylation modulates acetoacetate to drive tubule-macrophage inflammatory crosstalk in diabetic kidney disease.
    Metabolism. 2026;177:156510.
    PubMed     Abstract available


  10. LEANZA G, Faraj M, Cannata F, Viola V, et al
    Bone inflammation in postmenopausal women with type 2 diabetes or obesity in relation to Wnt signaling and bone strength.
    Metabolism. 2026 Jan 8:156492. doi: 10.1016/j.metabol.2026.156492.
    PubMed     Abstract available


  11. GERLACH PA, Gadgaard S, Madsen JS, Lindquist P, et al
    Global glucagon-like peptide-2 receptor activation linked to increased obesity risk in the UK Biobank.
    Metabolism. 2026 Jan 8:156489. doi: 10.1016/j.metabol.2025.156489.
    PubMed     Abstract available


  12. MUNOZ F, Gao Q, Mattanovich M, Trost K, et al
    Lysine potentiates insulin secretion via AASS-dependent catabolism and regulation of GABA content and signaling.
    Metabolism. 2026;174:156423.
    PubMed     Abstract available


    December 2025
  13. D'ADDIO F, Bucciarelli L, Lunati ME, Fiorina P, et al
    Metabolic and immune dysfunction at the crossroads between type 1 diabetes and neurodegeneration.
    Metabolism. 2025 Dec 17:156471. doi: 10.1016/j.metabol.2025.156471.
    PubMed     Abstract available


  14. YANG J, Yang X, Zheng Y, Wang A, et al
    27-Hydroxycholesterol exacerbates hepatic insulin resistance via plasma membrane cholesterol remodeling.
    Metabolism. 2025;173:156392.
    PubMed     Abstract available


    November 2025
  15. JINYI L, Xianguang D, Yuhan D, Haoyue H, et al
    Metabolic reprogramming in diabetic foot ulcers: mechanisms, therapeutic implications and future perspectives.
    Metabolism. 2025;175:156455.
    PubMed     Abstract available


  16. WANG Y, Sandforth A, von Schwartzenberg RJ, Ganslmeier M, et al
    Lifestyle intervention is more effective in high 1-hour post-load glucose than in prediabetes for restoring beta-cell function, reducing ectopic fat, and preventing type 2 diabetes.
    Metabolism. 2025 Nov 3:156430. doi: 10.1016/j.metabol.2025.156430.
    PubMed     Abstract available


  17. STUBBENDORFF A, Janzi S, Jukkola J, Morency M, et al
    Mini-review of the EAT-Lancet planetary health diet and its role in cardiometabolic disease prevention.
    Metabolism. 2025;172:156373.
    PubMed     Abstract available


    October 2025
  18. PAN L, He Y, Xiang Y, Mao B, et al
    Angiopoietin-like protein 8 mediates inflammation and fibrosis of tubular cells in diabetic kidney disease progression by interacting with Akt2.
    Metabolism. 2025 Oct 17:156418. doi: 10.1016/j.metabol.2025.156418.
    PubMed     Abstract available


  19. ASHLAW EF, Elfers CT, Chichura KS, Miranda IC, et al
    A melanocortin 4- and glucagon-like peptide 1 receptor multiple agonist for the treatment of diabetes and obesity.
    Metabolism. 2025 Oct 13:156414. doi: 10.1016/j.metabol.2025.156414.
    PubMed     Abstract available


  20. MISHRA RC, Mallat RK, John CM, Belke D, et al
    Administration of the K(Ca) channel activator SKA-31 improves long-term endothelial function, blood pressure regulation and cardiac performance in rats with type 2 diabetes.
    Metabolism. 2025 Oct 1:156410. doi: 10.1016/j.metabol.2025.156410.
    PubMed     Abstract available


    August 2025
  21. HENDLINGER M, Mastrototaro L, Exterkate M, Apostolopoulou M, et al
    Exercise training increases skeletal muscle sphingomyelinases and affects mitochondrial quality control in men with type 2 diabetes.
    Metabolism. 2025 Aug 2:156361. doi: 10.1016/j.metabol.2025.156361.
    PubMed     Abstract available


  22. HAKIM JP, Handelsman Y, Banerjee T
    Use of finerenone in patients with chronic kidney disease at high risk of heart failure.
    Metabolism. 2025;169:156297.
    PubMed     Abstract available


  23. HUANG H, Ruan H, Lu X, Chen S, et al
    Comprehensive assessment of the causal effects and metabolite mediators of glucose-lowering drug targets on cardio-renal-liver-metabolic health.
    Metabolism. 2025;169:156276.
    PubMed     Abstract available


    July 2025
  24. LIANG T, Jiang T, Liang Z, Chen Y, et al
    Lactiplantibacillus plantarum strain 84-3-derived l-glutamine ameliorates glucose homeostasis via AMPK/PPARgamma signaling pathway activation in type 2 diabetes.
    Metabolism. 2025;172:156357.
    PubMed     Abstract available


  25. ZHANG H, Wang W, Liu P, Zhang T, et al
    Flot2 protects against podocyte injury by maintaining the stability of synaptopodin in diabetic nephropathy.
    Metabolism. 2025;171:156354.
    PubMed     Abstract available


  26. GUO C, Li J, Yang X, Xie W, et al
    AEBP1 as a promising therapeutic target for skeletal muscle insulin resistance in type 2 diabetes mellitus: Convergent evidence from Mendelian randomization and functional validation.
    Metabolism. 2025 Jul 4:156339. doi: 10.1016/j.metabol.2025.156339.
    PubMed     Abstract available


    June 2025
  27. SU JB, Chen G, Sun QY, Fu X, et al
    USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice.
    Metabolism. 2025;170:156326.
    PubMed     Abstract available


    May 2025
  28. GALAN A, Garcia-Garcia F
    Revisiting gender differences in obesity and type 2 diabetes: Response letter.
    Metabolism. 2025 May 29:156307. doi: 10.1016/j.metabol.2025.156307.
    PubMed    


  29. WANG P, Zhang Y, Giovannucci EL
    Dietary context in the association between red meat consumption and risk of type 2 diabetes.
    Metabolism. 2025;169:156277.
    PubMed     Abstract available


    April 2025
  30. WU H, Yang Z, Zhou T, Wang J, et al
    UBC9 ameliorates diabetic cardiomyopathy by modulating cardiomyocyte mitophagy through NEDD4/RUNX2/PSEN2 axis.
    Metabolism. 2025 Apr 8:156264. doi: 10.1016/j.metabol.2025.156264.
    PubMed     Abstract available


  31. ZHONG Y, Wei J, Jiang R
    Revisiting gender differences in obesity and type 2 diabetes: Letter to the editor.
    Metabolism. 2025 Apr 3:156260. doi: 10.1016/j.metabol.2025.156260.
    PubMed    


    March 2025
  32. MOLDOVAN RA, Hidalgo MR, Castane H, Jimenez-Franco A, et al
    Landscape of sex differences in obesity and type 2 diabetes in subcutaneous adipose tissue: a systematic review and meta-analysis of transcriptomics studies.
    Metabolism. 2025 Mar 27:156241. doi: 10.1016/j.metabol.2025.156241.
    PubMed     Abstract available


  33. BHOWMICK DC, Ahn M, Bhattacharya S, Aslamy A, et al
    DOC2b enrichment mitigates proinflammatory cytokine-induced CXCL10 expression by attenuating IKKbeta and STAT-1 signaling in human islets.
    Metabolism. 2025;164:156132.
    PubMed     Abstract available


  34. KARAKASIS P, Patoulias D, Fragakis N, Mantzoros CS, et al
    Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition: Systematic review and network meta-analysis.
    Metabolism. 2025;164:156113.
    PubMed     Abstract available


    February 2025
  35. SCHORK A, Fritsche A, Schleicher ED, Peter A, et al
    Differential risk assessment in persons at risk of type 2 diabetes using urinary peptidomics.
    Metabolism. 2025;167:156174.
    PubMed     Abstract available


  36. HUANG J
    A systematic review & updated meta-analysis on the association between higher consumption of ultra processed foods and risk of diabetes and its complications: Letter to the editor.
    Metabolism. 2025 Feb 11:156156. doi: 10.1016/j.metabol.2025.156156.
    PubMed    


  37. SOUZA M, Moura FS, Lima LCV, Amaral MJM, et al
    A systematic review & updated meta-analysis on the association between higher consumption of ultra processed foods and risk of diabetes and its complications: Response letter.
    Metabolism. 2025 Feb 11:156155. doi: 10.1016/j.metabol.2025.156155.
    PubMed    


  38. CHEN J, Luo M, Xing Z, Chen Y, et al
    Start small, think big: MicroRNAs in diabetes mellitus and relevant cardiorenal-liver metabolic health spectrum.
    Metabolism. 2025 Feb 4:156153. doi: 10.1016/j.metabol.2025.156153.
    PubMed     Abstract available


  39. MEZZA T, Wewer Albrechtsen NJ, Di Giuseppe G, Ferraro PM, et al
    Human subjects with impaired beta-cell function and glucose tolerance have higher levels of intra-islet intact GLP-1.
    Metabolism. 2025;163:156087.
    PubMed     Abstract available


  40. KOKKORAKIS M, Folkertsma P, Forte JC, Wolffenbuttel BHR, et al
    GDF-15 improves the predictive capacity of steatotic liver disease non-invasive tests for incident morbidity and mortality risk for cardio-renal-metabolic diseases and malignancies.
    Metabolism. 2025;163:156047.
    PubMed     Abstract available


    January 2025
  41. SOUZA M, Moura FS, Lima LCV, Amaral MJM, et al
    Association between higher consumption of ultra-processed foods and risk of diabetes and its complications: A systematic review & updated meta-analysis.
    Metabolism. 2025 Jan 21:156134. doi: 10.1016/j.metabol.2025.156134.
    PubMed     Abstract available


  42. LUO YY, Ruan CS, Zhao FZ, Yang M, et al
    ZBED3 exacerbates hyperglycemia by promoting hepatic gluconeogenesis through CREB signaling.
    Metabolism. 2025;162:156049.
    PubMed     Abstract available


  43. DENG X, Tang C, Fang T, Li T, et al
    Disruption of branched-chain amino acid homeostasis promotes the progression of DKD via enhancing inflammation and fibrosis-associated epithelial-mesenchymal transition.
    Metabolism. 2025;162:156037.
    PubMed     Abstract available


    December 2024
  44. DOU C, Liu D, Kong L, Chen M, et al
    Shared genetic architecture of type 2 diabetes with muscle mass and function and frailty reveals comorbidity etiology and pleiotropic druggable targets.
    Metabolism. 2024 Dec 20:156112. doi: 10.1016/j.metabol.2024.156112.
    PubMed     Abstract available


  45. KIM JS, Jun JH, Lee J, Park S, et al
    HDAC6 mediates NLRP3 inflammasome activation in the pathogenesis of diabetic retinopathy.
    Metabolism. 2024 Dec 15:156108. doi: 10.1016/j.metabol.2024.156108.
    PubMed     Abstract available


    November 2024
  46. WU Q, Zeng Y, Geng K, Guo M, et al
    The role of IL-1 family cytokines in diabetic cardiomyopathy.
    Metabolism. 2024 Nov 25:156083. doi: 10.1016/j.metabol.2024.156083.
    PubMed     Abstract available


  47. CONGUR I, Mingrone G, Guan K
    Targeting endoplasmic reticulum stress as a potential therapeutic strategy for diabetic cardiomyopathy.
    Metabolism. 2024 Nov 6:156062. doi: 10.1016/j.metabol.2024.156062.
    PubMed     Abstract available


  48. ZHANG H, Zhou XD, Shapiro MD, Lip GYH, et al
    Global burden of metabolic diseases, 1990-2021.
    Metabolism. 2024;160:155999.
    PubMed     Abstract available


    August 2024
  49. MISHRA RC, Belke DD, Singh L, Wulff H, et al
    Targeting endothelial K(Ca) channels in vivo restores arterial and endothelial function in type 2 diabetic rats.
    Metabolism. 2024 Aug 18:156001. doi: 10.1016/j.metabol.2024.156001.
    PubMed     Abstract available


  50. ROSELL-DIAZ M, Petit-Gay A, Molas-Prat C, Gallardo-Nuell L, et al
    Metformin-induced changes in the gut microbiome and plasma metabolome are associated with cognition in men.
    Metabolism. 2024;157:155941.
    PubMed     Abstract available


  51. CAI Z, Yang Y, Zhong J, Ji Y, et al
    cGAS suppresses beta-cell proliferation by a STING-independent but CEBPbeta-dependent mechanism.
    Metabolism. 2024;157:155933.
    PubMed     Abstract available


    July 2024
  52. KANG JS, Cho NJ, Lee SW, Lee JG, et al
    RIPK3 causes mitochondrial dysfunction and albuminuria in diabetic podocytopathy through PGAM5-Drp1 signaling.
    Metabolism. 2024 Jul 30:155982. doi: 10.1016/j.metabol.2024.155982.
    PubMed     Abstract available


  53. SHU S, Cui H, Liu Z, Zhang H, et al
    Suppression of RCAN1 alleviated lipid accumulation and mitochondrial fission in diabetic cardiomyopathy.
    Metabolism. 2024 Jul 23:155977. doi: 10.1016/j.metabol.2024.155977.
    PubMed     Abstract available


  54. ZHAO M, Shen Z, Zheng Z, Xu Y, et al
    Cardiomyocyte LGR6 alleviates ferroptosis in diabetic cardiomyopathy via regulating mitochondrial biogenesis.
    Metabolism. 2024 Jul 20:155979. doi: 10.1016/j.metabol.2024.155979.
    PubMed     Abstract available


  55. RICHTER MM, Kemp IM, Heeboll S, Winther-Sorensen M, et al
    Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms.
    Metabolism. 2024;156:155915.
    PubMed     Abstract available


    June 2024
  56. HANDELSMAN Y, Anderson JE, Bakris GL, Ballantyne CM, et al
    DCRM 2.0: Multispecialty practice recommendations for the management of diabetes, cardiorenal, and metabolic diseases.
    Metabolism. 2024 Jun 4:155931. doi: 10.1016/j.metabol.2024.155931.
    PubMed     Abstract available


  57. SABATINI S, Nolan JJ, O'Donoghue G, Kennedy A, et al
    Baseline phenotypes with preserved beta-cell function and high insulin concentrations have the best improvements in glucose tolerance after weight loss: results from the prospective DEXLIFE and EGIR-RISC studies.
    Metabolism. 2024;155:155910.
    PubMed     Abstract available


    May 2024
  58. HUTTASCH M, Roden M, Kahl S
    Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease?
    Metabolism. 2024 May 21:155937. doi: 10.1016/j.metabol.2024.155937.
    PubMed     Abstract available


  59. LIAN LY, Targher G, Byrne CD, Liu WY, et al
    Resmetirom for MASH patients with diabetes: challenges and opportunities in the real world.
    Metabolism. 2024 May 15:155935. doi: 10.1016/j.metabol.2024.155935.
    PubMed    


    April 2024
  60. JEREMIAH SS, Moin ASM, Butler AE
    Virus-induced diabetes mellitus, revisiting infection etiology in light of SARS-CoV-2.
    Metabolism. 2024 Apr 18:155917. doi: 10.1016/j.metabol.2024.155917.
    PubMed     Abstract available


  61. ROSENDO-SILVA D, Gomes PB, Rodrigues T, Viana S, et al
    Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction.
    Metabolism. 2024;153:155788.
    PubMed     Abstract available


    March 2024
  62. HE Y, Qu L
    The role and mechanisms of non-coding RNAs in diabetic peripheral neuropathy.
    Metabolism. 2024 Mar 8:155833. doi: 10.1016/j.metabol.2024.155833.
    PubMed     Abstract available


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