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Articles published in Metabolism

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    June 2020
  1. MARRANO N, Biondi G, Cignarelli A, Perrini S, et al
    Functional loss of pancreatic islets in type 2 diabetes: how can we halt it?
    Metabolism. 2020 Jun 26:154304. doi: 10.1016/j.metabol.2020.154304.
    PubMed     Abstract available

  2. CHAMORRO-PAREJA N, Parthasarathy S, Annam J, Hoffman J, et al
    Unexpected high mortality in COVID-19 and diabetic ketoacidosis.
    Metabolism. 2020 Jun 23:154301. doi: 10.1016/j.metabol.2020.154301.

  3. DEWIDAR B, Kahl S, Pafili K, Roden M, et al
    Metabolic liver disease in diabetes - from mechanisms to clinical trials.
    Metabolism. 2020 Jun 19:154299. doi: 10.1016/j.metabol.2020.154299.
    PubMed     Abstract available

  4. STOIAN AP, Sachinidis A, Stoica RA, Nikolic D, et al
    The efficacy and safety of Dipeptyl Peptidase-4 inhibitors compared to other Oral glucose-lowering medications in the treatment of type 2 diabetes.
    Metabolism. 2020 Jun 15:154295. doi: 10.1016/j.metabol.2020.154295.
    PubMed     Abstract available

    May 2020
  5. YANG T, Heng C, Zhou Y, Hu Y, et al
    Targeting mammalian serine/threonine-protein kinase 4 through yes-associated protein/TEA domain transcription factor-mediated epithelial-mesenchymal transition ameliorates diabetic nephropathy orchestrated renal fibrosis.
    Metabolism. 2020 May 3:154258. doi: 10.1016/j.metabol.2020.154258.
    PubMed     Abstract available

    April 2020
  6. MEANS C
    Mechanisms of increased morbidity and mortality of SARS-CoV-2 infection in individuals with diabetes: what this means for an effective management strategy.
    Metabolism. 2020 Apr 28:154254. doi: 10.1016/j.metabol.2020.154254.

  7. MUKHTAZR S, Mukhtar S
    Mental Health and Psychological Distress in People with Diabetes during COVID-19.
    Metabolism. 2020 Apr 23:154248. doi: 10.1016/j.metabol.2020.154248.

  8. ANGELIDI AM, Belanger MJ, Mantzoros CS
    COVID-19 and diabetes mellitus: What we know, how our patients should be treated now, and what should happen next.
    Metabolism. 2020 Apr 19:154245. doi: 10.1016/j.metabol.2020.154245.

  9. GUO D, Mizukami H, Osonoi S, Takahashi K, et al
    Beneficial effects of combination therapy of canagliflozin and teneligliptin on diabetic polyneuropathy and beta-cell volume density in spontaneously type 2 diabetic Goto-Kakizaki rats.
    Metabolism. 2020 Apr 14:154232. doi: 10.1016/j.metabol.2020.154232.
    PubMed     Abstract available

  10. KLONOFF DC, Umpierrez GE
    COVID-19 in patients with diabetes: risk factors that increase morbidity.
    Metabolism. 2020 Apr 7:154224. doi: 10.1016/j.metabol.2020.154224.

  11. MENGOZZI A, Trico D, Nesti L, Petrie J, et al
    Disruption of fasting and post-load glucose homeostasis are largely independent and sustained by distinct and early major beta-cell function defects: a cross-sectional and longitudinal analysis of the Relationship between Insulin Sensitivity and Cardi
    Metabolism. 2020;105:154185.
    PubMed     Abstract available

    March 2020
  12. VAN CAMPENHOUT S, Tilleman L, Lefere S, Vandierendonck A, et al
    Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model.
    Metabolism. 2020 Mar 31:154220. doi: 10.1016/j.metabol.2020.154220.
    PubMed     Abstract available

  13. KATSIKI N, Ferrannini E, Mantzoros C
    New American Diabetes Association (ADA)/European Association for the Study of diabetes (EASD) guidelines for the pharmacotherapy of type 2 diabetes: placing them into a practicing physician's perspective.
    Metabolism. 2020 Mar 25:154218. doi: 10.1016/j.metabol.2020.154218.

  14. ZHOU J, Tan J
    Diabetes patients with COVID-19 need better blood glucose management in Wuhan, China.
    Metabolism. 2020;107:154216.

  15. HILL MA, Mantzoros C, Sowers JR
    Commentary: COVID-19 in Patients with Diabetes.
    Metabolism. 2020 Mar 24:154217. doi: 10.1016/j.metabol.2020.154217.

    February 2020
  16. MCCULLOCH LJ, Bramwell LR, Knight B, Kos K, et al
    Circulating and tissue specific transcription of angiopoietin-like protein 4 in human Type 2 diabetes.
    Metabolism. 2020 Feb 26:154192. doi: 10.1016/j.metabol.2020.154192.
    PubMed     Abstract available

  17. WEI X, Wei X, Lu Z, Li L, et al
    Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.
    Metabolism. 2020 Feb 12:154182. doi: 10.1016/j.metabol.2020.154182.
    PubMed     Abstract available

  18. ADAMS JD, Man CD, Laurenti MC, Andrade MDH, et al
    Fasting glucagon concentrations are associated with longitudinal decline of beta-cell function in non-diabetic humans.
    Metabolism. 2020 Feb 8:154175. doi: 10.1016/j.metabol.2020.154175.
    PubMed     Abstract available

    January 2020
  19. WANG P, Yang X, Zhang Z, Song J, et al
    Corrigendum to "Depletion of NAD pool contributes to impairment of endothelial progenitor cell mobilization in diabetes" [Metab Clin Exp 65 (2016) 852-862].
    Metabolism. 2020;104:154139.

  20. HSU YH, Chen YC, Chen YW, Chiu TH, et al
    Far-infrared radiation prevents decline in beta-cell mass and function in diabetic mice via the mitochondria-mediated Sirtuin1 pathway.
    Metabolism. 2020 Jan 9:154143. doi: 10.1016/j.metabol.2020.154143.
    PubMed     Abstract available

  21. VUILLEUMIER NC, Gauthier BR
    Time for a paradigm shift in treating type 1 diabetes mellitus: coupling inflammation to islet Regeneration.
    Metabolism. 2020 Jan 2:154137. doi: 10.1016/j.metabol.2020.154137.
    PubMed     Abstract available

    December 2019
  22. GUARDADO-MENDOZA R, Salazar-Lopez SS, de la Luz Alvarez-Canales MF, Vazquez DF, et al
    The combination of Linagliptin, Metformin and Lifestyle Modification to prevent Type 2 Diabetes (PRELLIM). A randomized clinical trial.
    Metabolism. 2019 Dec 27:154054. doi: 10.1016/j.metabol.2019.154054.
    PubMed     Abstract available

  23. RANJBAR G, Mikhailidis DP, Sahebkar A
    Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: Think out of the box!
    Metabolism. 2019;101:154001.
    PubMed     Abstract available

  24. KITAZAWA M, Fujihara K, Osawa T, Yamamoto M, et al
    Risk of coronary artery disease according to glucose abnormality status and prior coronary artery disease in Japanese men.
    Metabolism. 2019;101:153991.
    PubMed     Abstract available

    November 2019
  25. CHAVEZ-TALAVERA O, Wargny M, Pichelin M, Descat A, et al
    Bile acids associate with glucose metabolism, but do not predict conversion from impaired fasting glucose to diabetes.
    Metabolism. 2019 Nov 27:154042. doi: 10.1016/j.metabol.2019.154042.
    PubMed     Abstract available

  26. NAUCK MA
    The rollercoaster history of using physiological and pharmacological properties of incretin hormones to develop diabetes medications with a convincing benefit-risk relationship.
    Metabolism. 2019 Nov 27:154031. doi: 10.1016/j.metabol.2019.154031.

  27. XU BH, Sheng J, You YK, Huang XR, et al
    Deletion of Smad3 prevents renal fibrosis and inflammation in type 2 diabetic nephropathy.
    Metabolism. 2019 Nov 14:154013. doi: 10.1016/j.metabol.2019.154013.
    PubMed     Abstract available

  28. SUN Y, Zhou S, Guo H, Zhang J, et al
    Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function.
    Metabolism. 2019 Nov 7:154002. doi: 10.1016/j.metabol.2019.154002.
    PubMed     Abstract available

  29. TREMBLAY J, Hamet P
    Environmental and genetic contributions to diabetes.
    Metabolism. 2019;100S:153952.
    PubMed     Abstract available

    October 2019
  30. FUKUHARA S, Yasukawa K, Sato M, Ikeda H, et al
    Clinical usefulness of human serum nonmercaptalbumin to mercaptalbumin ratio as a biomarker for diabetic complications and disability in activities of daily living in elderly patients with diabetes.
    Metabolism. 2019 Oct 28:153995. doi: 10.1016/j.metabol.2019.153995.
    PubMed     Abstract available

  31. FARNGREN J, Ahren B
    Incretin-based medications (GLP-1 receptor agonists, DPP-4 inhibitors) as a means to avoid hypoglycaemic episodes.
    Metabolism. 2019;99:25-31.
    PubMed     Abstract available

    August 2019
  32. SUN Y, Gao Y, Chen J, Sun H, et al
    Evidence mapping of recommendations on diagnosis and therapeutic strategies for diabetes foot: an international review of 22 guidelines.
    Metabolism. 2019 Aug 5:153956. doi: 10.1016/j.metabol.2019.153956.
    PubMed     Abstract available

    July 2019
  33. JIANG Z, Zhou J, Li T, Tian M, et al
    Hepatic deficiency of Poldip2 in type 2 diabetes dampens lipid and glucose homeostasis.
    Metabolism. 2019 Jul 25:153948. doi: 10.1016/j.metabol.2019.153948.
    PubMed     Abstract available

  34. HUANG S, Ma S, Ning M, Yang W, et al
    TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice.
    Metabolism. 2019 Jul 8. pii: S0026-0495(19)30136.
    PubMed     Abstract available

    June 2019
    Initial injectable therapy in type 2 diabetes: key considerations when choosing between glucagon-like peptide 1 receptor agonists and insulin.
    Metabolism. 2019 Jun 27. pii: S0026-0495(19)30127.
    PubMed     Abstract available

    May 2019
  36. QUICLET C, Dittberner N, Gassler A, Stadion M, et al
    Pancreatic adipocytes mediate hypersecretion of insulin in diabetes-susceptible mice.
    Metabolism. 2019 May 17. pii: S0026-0495(19)30093.
    PubMed     Abstract available

    April 2019
  37. YANG T, Shu F, Yang H, Heng C, et al
    YY1:a novel therapeutic target for diabetic nephropathy orchestrated renal fibrosis.
    Metabolism. 2019 Apr 25. pii: S0026-0495(19)30085.
    PubMed     Abstract available

  38. ZENG Y, Mtintsilana A, Goedecke JH, Micklesfield LK, et al
    Alterations in the metabolism of phospholipids, bile acids and branched-chain amino acids predicts development of type 2 diabetes in black south African women: a prospective cohort study.
    Metabolism. 2019 Apr 4. pii: S0026-0495(19)30067.
    PubMed     Abstract available

  39. VAN NIEROP FS, de Jonge C, Kulik W, Bouvy N, et al
    Duodenal-jejunal lining increases postprandial unconjugated bile acid responses and disrupts the bile acid-FXR-FGF19 axis in humans.
    Metabolism. 2019;93:25-32.
    PubMed     Abstract available

    March 2019
  40. GILARDI F, Winkler C, Quignodon L, Diserens JG, et al
    Systemic PPARgamma deletion in mice provokes lipoatrophy, organomegaly, severe type 2 diabetes and metabolic inflexibility.
    Metabolism. 2019 Mar 13. pii: S0026-0495(19)30051.
    PubMed     Abstract available

  41. KOOPMAN ADM, Beulens JW, Voerman E, Rauh SP, et al
    GAD65 antibodies and incident type 2 Diabetes mellitus.
    Metabolism. 2019 Mar 7. pii: S0026-0495(19)30049.
    PubMed     Abstract available

    February 2019
  42. PERADZE N, Farr OM, Mantzoros CS
    Research developments in metabolism 2018.
    Metabolism. 2019;91:70-79.

    January 2019
  43. ZHOU Z, Sun B, Huang S, Jia W, et al
    The tRNA-associated dysregulation in diabetes mellitus.
    Metabolism. 2019 Jan 31. pii: S0026-0495(19)30032.
    PubMed     Abstract available

  44. KIM MJ, Kim MN, Min SH, Ham DS, et al
    Specific PERK inhibitors enhanced glucose-stimulated insulin secretion in a mouse model of type 2 diabetes.
    Metabolism. 2019 Jan 4. pii: S0026-0495(18)30267.
    PubMed     Abstract available

  45. AHMAD A, Ali T, Kim MW, Khan A, et al
    Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARalpha signaling in ob/ob and db/db transgenic mouse models.
    Metabolism. 2019;90:31-43.
    PubMed     Abstract available

    December 2018
  46. SHAH M, Laurenti MC, Man CD, Ma J, et al
    Contribution of endogenous glucagon-like Peptide-1 to changes in glucose metabolism and islet function in people with type 2 diabetes four weeks after roux-en-Y gastric bypass (RYGB).
    Metabolism. 2018 Dec 23. pii: S0026-0495(18)30265.
    PubMed     Abstract available

    November 2018
  47. LAYTON J, Powe C, Allard C, Battista MC, et al
    Maternal lipid profile differs by gestational diabetes physiologic subtype.
    Metabolism. 2018 Nov 20. pii: S0026-0495(18)30247.
    PubMed     Abstract available

    Burden of cancer attributable to obesity, type 2 diabetes and associated risk factors.
    Metabolism. 2018 Nov 6. pii: S0026-0495(18)30231.
    PubMed     Abstract available

    October 2018
  49. PATH G, Perakakis N, Mantzoros CS, Seufert J, et al
    Stem cells in the treatment of diabetes mellitus - focus on mesenchymal stem cells.
    Metabolism. 2018 Oct 17. pii: S0026-0495(18)30215.
    PubMed     Abstract available

  50. YARIBEYGI H, Katsiki N, Behnam B, Iranpanah H, et al
    MicroRNAs and type 2 diabetes mellitus: Molecular mechanisms and the effect of antidiabetic drug treatment.
    Metabolism. 2018;87:48-55.
    PubMed     Abstract available

    May 2018
  51. TSENG CH
    Metformin and risk of developing nasopharyngeal cancer in patients with type 2 diabetes mellitus.
    Metabolism. 2018 May 2. pii: S0026-0495(18)30115.
    PubMed     Abstract available

  52. YANG P, Huang T, Xu G
    Corrigendum to "The novel mineralocorticoid receptor antagonist finerenone in diabetic kidney disease: Progress and challenges" [Metabolism 65 (2016) 1342-1349].
    Metabolism. 2018;82:124.

    April 2018
  53. KINTIRAKI E, Goulis DG
    Gestational Diabetes Mellitus: multi-disciplinary treatment approaches.
    Metabolism. 2018 Apr 5. pii: S0026-0495(18)30097.
    PubMed     Abstract available

    March 2018
  54. DOKE T, Ishimoto T, Hayasaki T, Ikeda S, et al
    Lacking Ketohexokinase-A Exacerbates Renal Injury in Streptozotocin-induced Diabetic Mice.
    Metabolism. 2018 Mar 28. pii: S0026-0495(18)30092.
    PubMed     Abstract available

  55. BASOLO A, Burkholder J, Osgood K, Graham A, et al
    Exenatide has a Pronounced Effect on Energy Intake but not Energy Expenditure in Non-Diabetic Subjects with Obesity: A Randomized, Double-blind, Placebo-Controlled Trial.
    Metabolism. 2018 Mar 26. pii: S0026-0495(18)30089.
    PubMed     Abstract available

  56. ZHENG T, Liu H, Qin L, Chen B, et al
    Oxidative Stress-Mediated Influence of Plasma DPP4 Activity to BDNF Ratio on Mild Cognitive Impairment in Elderly Type 2 Diabetic Patients: Results From the GDMD Study in China.
    Metabolism. 2018 Mar 20. pii: S0026-0495(18)30086.
    PubMed     Abstract available

  57. QIU T, Li M, Tanner MA, Yang Y, et al
    Depletion of dendritic cells in perivascular adipose tissue improves arterial relaxation responses in type 2 diabetic mice.
    Metabolism. 2018 Mar 9. pii: S0026-0495(18)30068.
    PubMed     Abstract available

  58. CHO YY, Cho SI
    Metformin combined with dipeptidyl peptidase-4 inhibitors or metformin combined with sulfonylureas in patients with type 2 diabetes: A real world analysis of the South Korean national cohort.
    Metabolism. 2018 Mar 9. pii: S0026-0495(18)30081.
    PubMed     Abstract available

  59. REUTRAKUL S, Van Cauter E
    Sleep influences on obesity, insulin resistance, and risk of type 2 diabetes.
    Metabolism. 2018 Mar 3. pii: S0026-0495(18)30063.
    PubMed     Abstract available

    February 2018
  60. CHOI SR, Lim JH, Kim MY, Kim EN, et al
    Adiponectin Receptor Agonist AdipoRon Decreased Ceramide, and Lipotoxicity, and Ameliorated Diabetic Nephropathy.
    Metabolism. 2018 Feb 17. pii: S0026-0495(18)30043.
    PubMed     Abstract available

  61. TIMOTHY GARVEY W, Van Gaal L, Leiter LA, Vijapurkar U, et al
    Effects of Canagliflozin Versus Glimepiride on Adipokines and Inflammatory Biomarkers in Type 2 Diabetes.
    Metabolism. 2018 Feb 13. pii: S0026-0495(18)30041.
    PubMed     Abstract available

  62. LI TC, Li CI, Liu CS, Lin WY, et al
    Development and validation of prediction models for the risks of diabetes-related hospitalization and in-hospital mortality in patients with type 2 diabetes.
    Metabolism. 2018 Feb 13. pii: S0026-0495(18)30042.
    PubMed     Abstract available

  63. KINTIRAKI E, Dipla K, Triantafyllou A, Koletsos N, et al
    Blunted cerebral oxygenation during exercise in women with gestational diabetes mellitus: associations with macrovascular function and cardiovascular risk factors.
    Metabolism. 2018 Feb 1. pii: S0026-0495(18)30015.
    PubMed     Abstract available

    January 2018
  64. HOLINGUE C, Wennberg A, Berger S, Polotsky VY, et al
    Disturbed Sleep and Diabetes: A Potential Nexus of Dementia Risk.
    Metabolism. 2018 Jan 31. pii: S0026-0495(18)30029.
    PubMed     Abstract available

  65. NISHIHAMA K, Yasuma T, Yano Y, D' Alessandro-Gabazza CN, et al
    Anti-apoptotic activity of human matrix Metalloproteinase-2 attenuates diabetes mellitus.
    Metabolism. 2018 Jan 20. pii: S0026-0495(18)30022.
    PubMed     Abstract available

  66. WU R, Liu X, Yin J, Wu H, et al
    IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
    Metabolism. 2018 Jan 11. pii: S0026-0495(18)30007.
    PubMed     Abstract available

  67. BROSKEY NT, Obanda DN, Burton JH, Cefalu WT, et al
    Skeletal muscle ceramides and daily fat oxidation in obesity and diabetes.
    Metabolism. 2018 Jan 4. pii: S0026-0495(17)30359.
    PubMed     Abstract available

  68. PASTEL E, Price E, Sjoholm K, McCulloch LJ, et al
    Lysyl oxidase and adipose tissue dysfunction.
    Metabolism. 2018;78:118-127.
    PubMed     Abstract available

    December 2017
  69. SONODA N, Morimoto A, Tatsumi Y, Asayama K, et al
    A prospective study of the impact of diabetes mellitus on restrictive and obstructive lung function impairment: the Saku study.
    Metabolism. 2017 Dec 28. pii: S0026-0495(17)30343.
    PubMed     Abstract available

  70. XIAOYAN Z, Yang W, Wang J, Meng Y, et al
    FAM3 gene family: a promising therapeutical target for NAFLD and type 2 diabetes.
    Metabolism. 2017 Dec 5. pii: S0026-0495(17)30336.
    PubMed     Abstract available

  71. MIZUNO Y, Harada E, Nakagawa H, Morikawa Y, et al
    The diabetic heart utilizes ketone bodies as an energy source.
    Metabolism. 2017;77:65-72.
    PubMed     Abstract available

    November 2017
  72. WU D, Yan ZB, Cheng YG, Zhong MW, et al
    Deactivation of the NLRP3 inflammasome in infiltrating macrophages by duodenal-jejunal bypass surgery mediates improvement of beta cell function in type 2 diabetes.
    Metabolism. 2017 Nov 9. pii: S0026-0495(17)30304.
    PubMed     Abstract available

  73. ZIEGLER D, Strom A, Bonhof G, Puttgen S, et al
    Differential associations of lower cardiac vagal tone with insulin resistance and insulin secretion in recently diagnosed type 1 and type 2 diabetes.
    Metabolism. 2017 Nov 4. pii: S0026-0495(17)30301.
    PubMed     Abstract available

  74. SAHIN-EFE A, Upadhyay J, Ko BJ, Dincer F, et al
    Irisin and Leptin Concentrations in relation to Obesity, and Developing Type 2 Diabetes: a cross sectional and a prospective case-control study nested in the Normative Aging Study.
    Metabolism. 2017 Nov 3. pii: S0026-0495(17)30299.
    PubMed     Abstract available

  75. ITO Y, Hsu MF, Bettaieb A, Koike S, et al
    Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury.
    Metabolism. 2017;76:56-69.
    PubMed     Abstract available

    October 2017
  76. LI LJ, Tan KH, Aris IM, Man REK, et al
    Retinal Vasculature and 5-Year Metabolic Syndrome among Women with Gestational Diabetes Mellitus.
    Metabolism. 2017 Oct 16. pii: S0026-0495(17)30278.
    PubMed     Abstract available

  77. GALLO M, Muscogiuri G, Felicetti F, Faggiano A, et al
    Adverse glycaemic effects of cancer therapy: indications for a rational approach to cancer patients with diabetes.
    Metabolism. 2017 Oct 6. pii: S0026-0495(17)30265.
    PubMed     Abstract available

  78. GUELFI KJ, Ong MJ, Li S, Wallman KE, et al
    Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus.
    Metabolism. 2017;75:54-60.
    PubMed     Abstract available

  79. SONDERGAARD E, Johansen RF, Jensen MD, Nielsen S, et al
    Postprandial VLDL-TG metabolism in type 2 diabetes.
    Metabolism. 2017;75:25-35.
    PubMed     Abstract available

    September 2017
  80. CUI X, You L, Zhu L, Wang X, et al
    Change in circulating microRNA profile of obese children indicates future risk of adult diabetes.
    Metabolism. 2017 Sep 28. pii: S0026-0495(17)30250.
    PubMed     Abstract available

  81. SUVITAIVAL T, Bondia-Pons I, Yetukuri L, Poho P, et al
    Lipidome as a predictive tool in progression to type 2 diabetes in Finnish men.
    Metabolism. 2017 Sep 20. pii: S0026-0495(17)30230.
    PubMed     Abstract available

  82. UPADHYAY J, Polyzos SA, Perakakis N, Thakkar B, et al
    Pharmacotherapy of Type 2 Diabetes: An Update.
    Metabolism. 2017 Sep 8. pii: S0026-0495(17)30216.
    PubMed     Abstract available

    August 2017
  83. WANG H, Song Y, Sun S, Gao L, et al
    The association between immunoglobulin concentrations and prediabetes prevalence in a large Chinese cohort.
    Metabolism. 2017;73:77-84.
    PubMed     Abstract available

    July 2017
  84. THOMAS D, Apovian C
    Macrophage functions in lean and obese adipose tissue.
    Metabolism. 2017;72:120-143.
    PubMed     Abstract available

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