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CC Journal Club Our weekly journal club for junior residents and medical students |
Drug Resistance |
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1 AIDS |
Retrieve available abstracts of this week’s articles:
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People with four-class drug-resistant HIV-1 may have low levels of intact DNA.
AIDS. 2025;39:475-476.
PubMed
Abstract available
Mechanistic insights into the multitarget synergistic efficacy of farrerol and
beta-lactam antibiotics in combating methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2025 Feb 28:e0155124. doi: 10.1128/aac.01551.
PubMed
Abstract available
Optimizing phage therapy for carbapenem-resistant Enterobacter cloacae
bacteremia: insights into dose and timing.
Antimicrob Agents Chemother. 2025 Feb 26:e0168324. doi: 10.1128/aac.01683.
PubMed
Abstract available
Efforts to tackle antimicrobial resistance are having "limited impact," NAO
warns.
BMJ. 2025;388:r418.
PubMed
Increased Severity of Multidrug-Resistant Shigella sonnei Infections in People
Experiencing Homelessness.
Clin Infect Dis. 2025;80:339-346.
PubMed
Abstract available
"Seesaw effect" between daptomycin and ceftobiprole in daptomycin-resistant
methicillin-resistant staphylococcus aureus isolates.
Int J Antimicrob Agents. 2025 Feb 20:107469.
PubMed
Abstract available
The hidden threat: Klebsiella pneumoniae may develop co-resistance to colistin
and cefiderocol under pressure of colistin.
Int J Antimicrob Agents. 2025;65:107445.
PubMed
Abstract available
Integrons are key players in the spread of beta-lactamase-encoding genes.
Int J Antimicrob Agents. 2025;65:107421.
PubMed
Abstract available
Characterization of a novel KPC-2 variant, KPC-228, conferring resistance to
ceftazidime-avibactam in an ST11-KL64 hypervirulent Klebsiella pneumoniae.
Int J Antimicrob Agents. 2025;65:107411.
PubMed
Abstract available
Temporal, regional, and demographic differences among antimicrobial-resistant
domestic Campylobacter jejuni human infections across the United States,
2013-2019.
Int J Antimicrob Agents. 2025 Feb 20:107467.
PubMed
Abstract available
Clinical characteristics, therapy and outcome of bloodstream infections caused by
vancomycin-resistant enterococci: a multicentre clinical experience.
J Antimicrob Chemother. 2025 Feb 25:dkaf055. doi: 10.1093.
PubMed
Abstract available
Genotypic and phenotypic analyses of two distinct sets of Pseudomonas aeruginosa
urinary tract isolates.
J Med Microbiol. 2025;74.
PubMed
Abstract available
Retreatment of patients with chronic hepatitis C, subtype 3a, and cirrhosis, who
previously failed a regimen containing second-generation NS5A inhibitors with
sofosbuvir + glecaprevir/pibrentasvir and ribavirin for 16-24 weeks.
J Virol. 2025 Jan 22:e0184324. doi: 10.1128/jvi.01843.
PubMed
Abstract available
Resistance mutations that distinguish HIV-1 envelopes with discordant VRC01
phenotypes from multi-lineage infections in the HVTN703/HPTN081 trial:
implications for cross-resistance.
J Virol. 2025 Jan 16:e0173024. doi: 10.1128/jvi.01730.
PubMed
Abstract available
Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2
independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike
mutation E484D.
J Virol. 2025 Jan 10:e0123024. doi: 10.1128/jvi.01230.
PubMed
Abstract available
Five Engineering Advancements That May Help Solve the Growing Threat of
Antimicrobial Resistance.
JAMA. 2025 Feb 28. doi: 10.1001/jama.2024.28174.
PubMed
Predominance of extensively-drug resistant Acinetobacter baumannii carrying bla
OXA-23 in Jordanian patients admitted to the intensive care units.
PLoS One. 2025;20:e0317798.
PubMed
Abstract available
Machine learning for predicting antimicrobial resistance in critical and
high-priority pathogens: A systematic review considering antimicrobial
susceptibility tests in real-world healthcare settings.
PLoS One. 2025;20:e0319460.
PubMed
Abstract available
Widespread dissemination of Salmonella, Escherichia coli and Campylobacter
resistant to medically important antimicrobials in the poultry production
continuum in Canada.
PLoS One. 2025;20:e0319086.
PubMed
Abstract available
Mutational alterations in the QRDR regions associated with fluoroquinolone
resistance in Pseudomonas aeruginosa of clinical origin from Savar, Dhaka.
PLoS One. 2025;20:e0302352.
PubMed
Abstract available
An experimental study on the lytic bacteriophage MSP15 with wide-spectrum
targeting methicillin-resistant Staphylococcus aureus.
Virology. 2025;605:110452.
PubMed
Abstract available
Thank you for your interest in scientific medicine.