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Articles published in Brain Dev

Retrieve available abstracts of 69 articles:
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Single Articles


    October 2026
  1. OU YM, He MF, Yan FJ, Teng TX, et al
    Novel splice site variants in GBA1 are associated with Gaucher disease and genotype-phenotype correlations.
    Brain Dev. 2026;48:104584.
    PubMed     Abstract available


    September 2026
  2. KANEKO N, Yamazaki T, Fukushima R, Iimuro S, et al
    Effect of Doctor Car dispatch on neurological outcomes in children with status epilepticus: A single-Center retrospective cohort study.
    Brain Dev. 2026;48:104596.
    PubMed     Abstract available


  3. SATTAPORN C, Lusawat A, Sudachan P, Rojanawatsirivej A, et al
    Real-world clinical utility of exome sequencing in pediatric drug-resistant epilepsy: Experience from a tertiary center in Thailand.
    Brain Dev. 2026;48:104593.
    PubMed     Abstract available


    August 2026
  4. SEREF IS, Ozturk Z, Ozbas C, Serdaroglu E, et al
    Comparison of oral prednisolone and ACTH therapies in infantile epileptic spasms syndrome: using BASED and E-Chess scores.
    Brain Dev. 2026;48:104587.
    PubMed     Abstract available


  5. SAMANTA D
    Early infantile developmental and epileptic encephalopathy: clinical spectrum, diagnosis, outcomes, and evolving treatment strategies.
    Brain Dev. 2026;48:104581.
    PubMed     Abstract available


  6. OKANISHI T, Sakuma S, Kikuchi K, Ito S, et al
    Executive summary of the Japanese clinical practice guidelines for tuberous sclerosis complex-associated epilepsy 2025.
    Brain Dev. 2026;48:104583.
    PubMed     Abstract available


    July 2026
  7. OBA A, Matsuura R, Horita H, Daida A, et al
    Vigabatrin therapy for infantile epileptic spasms syndrome with periventricular leukomalacia.
    Brain Dev. 2026;48:104574.
    PubMed     Abstract available


  8. NISHIYAMA M, Ueda Y, Matsuura R, Shiohama T, et al
    Clinical practices in prehospital rescue medication use for pediatric status epilepticus in Japan: a nationwide questionnaire survey.
    Brain Dev. 2026;48:104573.
    PubMed     Abstract available


    June 2026
  9. YUCEL G
    From weather stations to the home environment: Refining seizure prediction in pediatric drug-resistant epilepsy.
    Brain Dev. 2026;48:104562.
    PubMed    


  10. KILIC KM, Aydin H
    Ketogenic diet in children with epilepsy: A bibliometric and science mapping analysis of global research.
    Brain Dev. 2026;48:104557.
    PubMed     Abstract available


    April 2026
  11. BEKTAS H, Tagiyev A, Gunbey C, Konuskan B, et al
    Screening for serum antineuronal antibodies in pediatric epilepsy.
    Brain Dev. 2026;48:104538.
    PubMed     Abstract available


  12. MATSUURA R, Hamano SI, Oba A, Horita H, et al
    Dynamic thalamo-cortical perfusion changes in myoclonic-atonic seizures captured by ictal technetium-99m ethyl cysteinate dimer single-photon emission computed tomography: A case report.
    Brain Dev. 2026;48:104537.
    PubMed     Abstract available


  13. WICKENS S, Gummersall P, Brown T
    Cognitive functioning in children with both epilepsy and ADHD: A systematic review and meta-analysis.
    Brain Dev. 2026;48:104533.
    PubMed     Abstract available


    March 2026
  14. AYDIN S, Oz Tuncer G, Bayir GK, Aksoy A, et al
    The Turkish version of neurological disorders depression inventory epilepsy for youth (NDDI-E-Y); validity and reliability study.
    Brain Dev. 2026;48:104532.
    PubMed     Abstract available


  15. ARAI Y, Okanishi T, Noma H, Sunada H, et al
    Association of weather with seizure incidence in children with drug-resistant epilepsy: A multicenter prospective observational study.
    Brain Dev. 2026;48:104530.
    PubMed     Abstract available


  16. HAMIDUN MAJID NA, Fong CY, Jayanath S, Li L, et al
    Executive function deficits among Malaysian children with epilepsy.
    Brain Dev. 2026;48:104528.
    PubMed     Abstract available


  17. FONSECA LD, Carnes S, Kumar G
    From a caregiver perspective: Quality of life of children with epilepsy and autism spectrum disorder - a single site case-control study.
    Brain Dev. 2026;48:104526.
    PubMed     Abstract available


  18. NISHIYAMA M, Ueda Y, Matsuura R, Shiohama T, et al
    Management of pediatric status epilepticus after hospital arrival in Japan: A nationwide questionnaire survey.
    Brain Dev. 2026;48:104524.
    PubMed     Abstract available


    February 2026
  19. KAWAGUCHI T, Okanishi T, Ohta K, Arai Y, et al
    Incidence of new onset neurological disorders due to convulsive status epilepticus in children: A long-term population-based study in Tottori prefecture, Japan.
    Brain Dev. 2026;48:104518.
    PubMed     Abstract available


  20. GUNBEY C, Muratoglu B, Ozdemir C, Cetinkaya DU, et al
    Senescence markers in peripheral blood mononuclear cells in pediatric drug-resistant epilepsy.
    Brain Dev. 2026;48:104511.
    PubMed     Abstract available


  21. YAVUZ M, Gulagiz F, Unalp A, Karaoglu P, et al
    Electroencephalogram abnormalities in children presenting with language development delay.
    Brain Dev. 2026;48:104504.
    PubMed     Abstract available


  22. DUMAN KAYAR C, Avci R, Kurekci F, Oney Yilmaz C, et al
    Evaluation of perinatal arterial ischemic stroke patients: Underlying etiologic factors and long-term prognosis.
    Brain Dev. 2026;48:104501.
    PubMed     Abstract available


  23. STJERNA S, Hamalainen LM, Videman M
    Does in utero exposure to antiseizure medications affect the trajectory of cognitive development from 2 to 6 years of age?
    Brain Dev. 2026;48:104487.
    PubMed     Abstract available


    January 2026
  24. WANG Z, Hu D, Dong X, Zhou W, et al
    The global research hotspots and future trends of infantile epileptic spasms syndrome: A bibliometric analysis of trends and themes.
    Brain Dev. 2026;48:104500.
    PubMed     Abstract available


  25. SANRI A, Akca U, Mutlu MB, Sezer O, et al
    Targeted gene panel testing in pediatric epilepsy: Diagnostic outcomes and expanding genetic insights.
    Brain Dev. 2026;48:104498.
    PubMed     Abstract available


    December 2025
  26. YUCEL G, Ekici NY
    Diagnostic advances in the etiology of cytotoxic lesions of the corpus callosum (CLOCC): epilepsy relationship and ADC radiomics perspective.
    Brain Dev. 2025;48:104494.
    PubMed    


  27. KUMAZAKI K, Okanishi T, Ohta K, Sasaki M, et al
    A patient presenting with chapeau de gendarme and three phase-ictal EEG pattern: Suggesting a focus in the interhemispheric fissure.
    Brain Dev. 2025;47:104467.
    PubMed     Abstract available


  28. YAMADA M, Natsume J, Maki Y, Ishimaru S, et al
    Clinical profiles of tuberous sclerosis complex: A regionally based survey.
    Brain Dev. 2025;47:104479.
    PubMed     Abstract available


    November 2025
  29. ENYAMA D, Massi DG, Njinkui DN, Abdourahmani ZB, et al
    Childhood epilepsy in Cameroon: Clinical patterns, predictive factors, and educational impact at a tertiary hospital.
    Brain Dev. 2025;47:104485.
    PubMed     Abstract available


    October 2025
  30. KOBAYASHI Y, Sakuma S, Morimoto E, Fujii H, et al
    Refractory myoclonic epilepsy and progressive movement disorder arising from recurrent DHDDS variants in Japanese patients: a case series.
    Brain Dev. 2025;47:104478.
    PubMed     Abstract available


    September 2025
  31. MATSUURA R, Hamano SI, Daida A, Oba A, et al
    Serum matrix metallopeptidase-9 levels in patients with infantile epileptic spasms syndrome before and after the initiation of vigabatrin therapy.
    Brain Dev. 2025;47:104447.
    PubMed     Abstract available


  32. SONG ES, Lee S, Kim YO
    Electroclinical biomarkers predicting EEG normalization and polytherapy needs in self-limited epilepsy with centrotemporal spikes.
    Brain Dev. 2025;47:104449.
    PubMed     Abstract available


    August 2025
  33. CHEN J, Zheng T, Liu J
    Unpacking the genetic landscape of epilepsy: key considerations for future research and clinical translation.
    Brain Dev. 2025;47:104429.
    PubMed    


  34. APHALE P, Dokania S, Shekhar H
    Letter to the editor: Immune dysregulation in new-onset refractory status epilepticus (NORSE): current insights and therapeutic perspectives.
    Brain Dev. 2025;47:104422.
    PubMed    


  35. ESER M, Hekimoglu G, Kutlubay B
    Epilepsy as a multifaceted neurological disease: insights from a genetic study of novel gene variants.
    Brain Dev. 2025;47:104418.
    PubMed     Abstract available


    July 2025
  36. HANIN A, Hirsch LJ
    Immune dysregulation in new-onset refractory status epilepticus (NORSE): current insights and therapeutic perspectives.
    Brain Dev. 2025;47:104406.
    PubMed     Abstract available


  37. KANEMURA H
    Association between epilepsy and attention deficit/hyperactivity disorder - correlation between interictal epileptiform discharges and behavioral disturbances.
    Brain Dev. 2025;47:104403.
    PubMed     Abstract available


  38. WATANABE S, Enokizono T, Nishimura M, Maruo K, et al
    Valproate and lamotrigine combination therapy in children with drug-resistant focal epilepsy: an observational analysis focusing on neuroimaging abnormalities.
    Brain Dev. 2025;47:104395.
    PubMed     Abstract available


  39. TAKEUCHI H, Kikuchi K, Takeda R, Hirata Y, et al
    Characteristics of withdrawal seizures in children with refractory status epilepticus who responded favorably to continuous midazolam therapy.
    Brain Dev. 2025;47:104394.
    PubMed     Abstract available


    June 2025
  40. CAMPANARIO DA SILVA PEREIRA C, Gomes Dantas FD, da Rosa Baratela WA, Antunes da Costa F, et al
    Tuberous sclerosis complex: Clinical, genetic and 7T-MRI neuroimaging findings.
    Brain Dev. 2025;47:104386.
    PubMed     Abstract available


  41. YUN HJ, Kim SY, Kim W, Lee S, et al
    Epilepsy phenotypes and responses to antiseizure medications in pediatric patients with EEF1A2-related epilepsy.
    Brain Dev. 2025;47:104382.
    PubMed     Abstract available


  42. CARABALLO RH, Fortini S, Beltran L, Semprino M, et al
    Focus on epilepsy and epilepsy syndromes in children with autism spectrum disorders: a study of 74 patients.
    Brain Dev. 2025;47:104385.
    PubMed     Abstract available


  43. MORITA S, Yamauchi T, Tamura Y, Suzuki T, et al
    Endocrinological study of low-dose adrenocorticotropic hormone therapy without tapering in infantile epileptic spasms syndrome.
    Brain Dev. 2025;47:104376.
    PubMed     Abstract available


  44. PALANCI O, Kamasak T, Aydin Kasap Z, Eyuboglu I, et al
    Volumetric and microstructural changes in the Hippocampus and cingulum in children with west syndrome.
    Brain Dev. 2025;47:104365.
    PubMed     Abstract available


    May 2025
  45. SAENCHAI W, Manopunya S, Kosarat S, Khuwuthyakorn V, et al
    Drug-resistant epilepsy in children post-neonatal seizures: Clinical profiles and predictors.
    Brain Dev. 2025;47:104373.
    PubMed     Abstract available


    April 2025
  46. YANG Y, Kang J, Zhang Y, Cai Y, et al
    Diagnostic value of serum miRNA-134-3p and miRNA-155-5p for monitoring seizure control in pediatric epilepsy.
    Brain Dev. 2025;47:104357.
    PubMed     Abstract available


    March 2025
  47. ITO S, Nishikawa A, Kuroiwa R, Honda K, et al
    COVID-19 infection and vaccination in children with Dravet syndrome or infantile epileptic spasms syndrome: An internet survey in Japan.
    Brain Dev. 2025;47:104352.
    PubMed     Abstract available


    February 2025
  48. TEKIN HG, Edem P
    Video game exposure in children with epilepsy: EEG and clinical findings.
    Brain Dev. 2025;47:104329.
    PubMed     Abstract available


    January 2025
  49. KOBAYASHI K, Shibata T, Tsuchiya H, Akiyama M, et al
    Hypotheses of pathophysiological mechanisms in epileptic encephalopathies: A review.
    Brain Dev. 2025;47:104318.
    PubMed     Abstract available


  50. SHIM Y, Kim H, Chae JH, Kim KJ, et al
    Analysis of initial seizure characteristics in patients with infantile onset genetic epilepsy.
    Brain Dev. 2025;47:104319.
    PubMed     Abstract available


    December 2024
  51. TAKEUCHI H, Kikuchi K, Takeda R, Hirata Y, et al
    Quantitative analysis of (123)I-iomazenil single-photon emission computed tomography findings from patients with infantile epileptic spasm syndrome.
    Brain Dev. 2024;47:104314.
    PubMed     Abstract available


  52. KIKUCHI K, Kuki I, Nishiyama M, Ueda Y, et al
    Japanese guidelines for treatment of pediatric status epilepticus - 2023.
    Brain Dev. 2024;47:104306.
    PubMed     Abstract available


    November 2024
  53. WENG Y, Rao X, Ma B, Lin X, et al
    Efficacy, safety, and tolerability of adjunctive perampanel in the treatment of pediatric patients aged 4-18 years with epilepsy: A single-center, retrospective, observational real-world study.
    Brain Dev. 2024;47:104305.
    PubMed     Abstract available


  54. TSUCHIYA H, Shibata T, Sasaki T, Akiyama M, et al
    A retrospective study on post-operative recovery of daily living activity after total corpus callosotomy.
    Brain Dev. 2024;46:339-343.
    PubMed     Abstract available


    October 2024
  55. WU H, Huang C, Xiong S
    Gut microbiota as a potential therapeutic target for children with cerebral palsy and epilepsy.
    Brain Dev. 2024 Oct 18:S0387-7604(24)00127.
    PubMed     Abstract available


  56. SHIMOJIMA YAMAMOTO K, Shimomura R, Shoji H, Yamamoto T, et al
    Glass syndrome derived from chromosomal breakage downstream region of SATB2.
    Brain Dev. 2024;46:281-285.
    PubMed     Abstract available


    September 2024
  57. SHIDE-MORIGUCHI Y, Yamamoto N, Kuki I, Sakuma H, et al
    Myelin oligodendrocyte glycoprotein antibody-associated cerebral cortical encephalitis with super-refractory status epilepticus.
    Brain Dev. 2024 Sep 10:S0387-7604(24)00126.
    PubMed     Abstract available


    July 2024
  58. MITSUMATSU T, Ito Y, Maki Y, Yamamoto H, et al
    Epileptic foci and networks in children with epilepsy after acute encephalopathy with biphasic seizures and late reduced diffusion.
    Brain Dev. 2024 Jul 31:S0387-7604(24)00098.
    PubMed     Abstract available


    April 2024
  59. SILVA S, Rosas M, Guerra B, Munoz M, et al
    Adolescent-onset epilepsy and deterioration associated with CAD deficiency: A case report.
    Brain Dev. 2024 Apr 18:S0387-7604(24)00057.
    PubMed     Abstract available


    March 2024
  60. TAKEUCHI H, Higurashi N, Toga Y
    Prophylactic antiseizure medications for recurrent status epilepticus in nonsyndromic childhood epilepsy.
    Brain Dev. 2024 Mar 21:S0387-7604(24)00043.
    PubMed     Abstract available


  61. YUKSEL MF, Dogulu N, Yildirim M, Kose E, et al
    Metabolic etiologies in children with infantile epileptic spasm syndrome: Experience at a tertiary pediatric neurology center.
    Brain Dev. 2024 Mar 16:S0387-7604(24)00042.
    PubMed     Abstract available


    January 2024
  62. AKIYAMA T, Saigusa D, Inoue T, Tokorodani C, et al
    Exploration of urine metabolic biomarkers for new-onset, untreated pediatric epilepsy: A gas and liquid chromatography mass spectrometry-based metabolomics study.
    Brain Dev. 2024 Jan 2:S0387-7604(23)00209-7. doi: 10.1016/j.braindev.2023.
    PubMed     Abstract available


    December 2023
  63. NISHIOKA M, Motobayashi M, Fukuyama T, Inaba Y, et al
    Risk factors for post-encephalopathic epilepsy in patients with acute encephalopathy with biphasic seizures and late reduced diffusion.
    Brain Dev. 2023 Dec 18:S0387-7604(23)00194.
    PubMed     Abstract available


  64. DE KNEGT VE, Borresen ML, Knudsen M, Thomsen KM, et al
    Current state of hemispherectomy and callosotomy for pediatric refractory epilepsy in Denmark.
    Brain Dev. 2023 Dec 2:S0387-7604(23)00179-1. doi: 10.1016/j.braindev.2023.
    PubMed     Abstract available


    November 2023
  65. DILENA R, Striano P, Traverso M, Viri M, et al
    Corrigendum to "Dramatic effect of levetiracetam in early-onset epileptic encephalopathy due to STXBP1 mutation" [Brain Dev. 38(1) (2016) 128-131].
    Brain Dev. 2023 Nov 24:S0387-7604(23)00176.
    PubMed    


  66. ANUAR MA, Lee JX, Musa H, Abd Hadi D, et al
    Severe and rare neurological manifestations following COVID-19 infection in children: A Malaysian tertiary centre experience.
    Brain Dev. 2023;45:547-553.
    PubMed     Abstract available


  67. AMORE G, Cali E, Spano M, Ceravolo G, et al
    ATP6V1B2-related disorders featuring Lennox-Gastaut-syndrome: A case-based overview.
    Brain Dev. 2023;45:588-596.
    PubMed     Abstract available


    October 2023
  68. UEDA Y, Furugen A, Kobayashi M, Sato Y, et al
    Use of lacosamide for focal epilepsy in a child with kidney failure undergoing peritoneal dialysis.
    Brain Dev. 2023 Oct 30:S0387-7604(23)00156.
    PubMed     Abstract available


    August 2023
  69. SHIRAISHI H, Egawa K, Murakami K, Nakajima M, et al
    Transcutaneous auricular vagus nerve stimulation therapy in patients with cognitively preserved structural focal epilepsy: A case series report.
    Brain Dev. 2023 Aug 30:S0387-7604(23)00148.
    PubMed     Abstract available


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