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  Epilepsy

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15.12.2025

1 BMC Neurol
3 Brain
1 Brain Dev
2 Childs Nerv Syst
6 Epilepsia
2 Epilepsy Res
4 Epileptic Disord
2 J Neurol
1 J Neurol Neurosurg Psychiatry
1 J Neurophysiol
2 Lancet Neurol
3 Neurology
1 Neuropediatrics
1 Pediatr Neurol
1 Pediatr Neurosurg
1 Proc Natl Acad Sci U S A
10 Seizure


  Retrieve available abstracts of this week’s articles:
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Single Articles


    BMC Neurol

  1. HE W, Xu M, Lin R, Wang S, et al
    Novel prognostic score based on the monocyte-to-lymphocyte ratio and CAVE score for epilepsy after primary intracerebral hemorrhage.
    BMC Neurol. 2025 Dec 4. doi: 10.1186/s12883-025-04562.
    PubMed         Abstract available


    Brain

  2. TOGO M, Lyu D, Huang W, Pantis S, et al
    Electrophysiological connections linking medial pulvinar, anterior nuclei of the thalamus and the hippocampus.
    Brain. 2025;148:4315-4324.
    PubMed         Abstract available

  3. XIE K, Korzun J, Zhou DJ, Chang E, et al
    Comparative effectiveness of anti-seizure medications in emulated trials using medical informatics.
    Brain. 2025;148:4288-4298.
    PubMed         Abstract available

  4. MAKHOUL GS, Doss DJ, Johnson GW, Withers CP, et al
    Collapse of interictal suppressive networks permits seizure spread.
    Brain. 2025;148:4275-4287.
    PubMed         Abstract available


    Brain Dev

  5. KUMAZAKI K, Okanishi T, Ohta K, Sasaki M, et al
    A patient presenting with chapeau de gendarme and three phase-ictal EEG pattern: Suggesting a focus in the interhemispheric fissure.
    Brain Dev. 2025;47:104467.
    PubMed         Abstract available


    Childs Nerv Syst

  6. GEORGE DD, LoPresti MA, Shahin MN, Widjaja E, et al
    Neurostimulation in children with drug-resistant epilepsy: strategies in subcortical targeting and systematic review of the evidence.
    Childs Nerv Syst. 2025;41:411.
    PubMed         Abstract available

  7. CAVALHEIRO S, Padua WL, Novo PC, de Souza Melo TC, et al
    Fourth ventricular hamartoma presenting with epileptic spasms: case-based review and surgical considerations.
    Childs Nerv Syst. 2025;41:409.
    PubMed         Abstract available


    Epilepsia

  8. GRAVITIS AC, Wennberg R, Carlen PL, Chinvarun Y, et al
    Cardiorespiratory cross-frequency coupling biomarker for sudden unexpected death in epilepsy.
    Epilepsia. 2025 Dec 13. doi: 10.1002/epi.70057.
    PubMed         Abstract available

  9. SEECK M, Nascimento FA, Benbadis S, Tatum WO, et al
    Comment on "Incidental interictal epileptiform discharges in infants with nonepileptic events" by Montenegro et al.
    Epilepsia. 2025 Dec 12. doi: 10.1111/epi.18686.
    PubMed        

  10. MONTENEGRO MA, Tsuha M, Baccin F, Sattar S, et al
    Response: "Incidental interictal epileptiform discharges in infants with nonepileptic events".
    Epilepsia. 2025 Dec 12. doi: 10.1111/epi.18688.
    PubMed        

  11. ORTMAN C, Coorg R, Ali I, Clarke D, et al
    Clinical outcomes following stereotactic MRI-guided laser ablation in children with tuberous sclerosis complex and intractable epilepsy.
    Epilepsia. 2025 Dec 9. doi: 10.1111/epi.70036.
    PubMed         Abstract available

  12. DURANTE GL, Tyler AL, Scott RC, Hernan AE, et al
    Meta-analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape.
    Epilepsia. 2025 Dec 8. doi: 10.1111/epi.70035.
    PubMed         Abstract available

  13. ORTIZ S, Bagliani C, Lin SXN, Kusay AS, et al
    Early neurological symptoms and epilepsy outcomes in individuals with the recurrent GABRG2 p.(Ala106Thr) gain-of-function variant: Structural and phenotypic insights.
    Epilepsia. 2025 Dec 6. doi: 10.1111/epi.70045.
    PubMed         Abstract available


    Epilepsy Res

  14. TAHA M, Stephen L, Nichol S, Yule S, et al
    Evaluating the impact of cenobamate in the management in patients with drug resistant focal epilepsy - A retrospective real world observational study of patients attending NHS Greater Glasgow and Clyde.
    Epilepsy Res. 2025;220:107717.
    PubMed         Abstract available

  15. IASINOVSCHI N, Tong E, Bicknell L, Baumer FM, et al
    Elevated thalamic blood flow in self-limited epilepsy with centrotemporal spikes.
    Epilepsy Res. 2025;220:107716.
    PubMed         Abstract available


    Epileptic Disord

  16. NUMOTO S, Kurahashi H, Okumura A
    Fenfluramine for late-onset epileptic spasms.
    Epileptic Disord. 2025 Dec 10. doi: 10.1002/epd2.70153.
    PubMed        

  17. CHANDRASEKHARAN SV, Nandana J, Menon RN, Vilanilam G, et al
    Does intraoperative electrocorticography alter seizure outcomes after temporal lobe epilepsy surgery?
    Epileptic Disord. 2025 Dec 5. doi: 10.1002/epd2.70141.
    PubMed         Abstract available

  18. SAHU P, Kashyap S, Kumar A, Munshi A, et al
    Uncovering common genetic risk factors in migraine and epilepsy through whole exome sequencing.
    Epileptic Disord. 2025 Dec 12. doi: 10.1002/epd2.70147.
    PubMed         Abstract available

  19. CUI C, Zhou X, Wang J, Zhao Q, et al
    Prevalence, comorbidities, and mortality of epilepsy in an older Chinese population: The Shanghai Aging Study.
    Epileptic Disord. 2025 Dec 13. doi: 10.1002/epd2.70151.
    PubMed         Abstract available


    J Neurol

  20. PREMARATNE S, Zoghi M, Antonic-Baker A, Chen Z, et al
    Non-invasive neurostimulation for drug-resistant epilepsy: systematic review and meta-analysis of effectiveness, safety, and optimal stimulation parameters.
    J Neurol. 2025;273:7.
    PubMed         Abstract available

  21. CHEN S, Quan Y, Yin F, Peng J, et al
    Clinical and genetics spectrum of 392 Chinese patients with genetic epilepsy with febrile seizures plus.
    J Neurol. 2025;273:18.
    PubMed         Abstract available


    J Neurol Neurosurg Psychiatry

  22. SHANKAR R, Henley WE, Allaudin S, Watkins LV, et al
    Epilepsy-related premature mortality in adults with intellectual disability in England: a population-based analysis.
    J Neurol Neurosurg Psychiatry. 2025 Dec 10:jnnp-2025-337291.
    PubMed         Abstract available


    J Neurophysiol

  23. ELLIOTT MAT, Andrews JP, van der Molen T, Geng J, et al
    Microscale maps of bursting dynamics across human hippocampal slices from epilepsy patients.
    J Neurophysiol. 2025 Dec 12. doi: 10.1152/jn.00217.2025.
    PubMed         Abstract available


    Lancet Neurol

  24. O'BRIEN TJ
    Epilepsy research in 2025: sudden unexpected death in epilepsy, artifical intelligence and seizure classification.
    Lancet Neurol. 2026;25:16-18.
    PubMed        

  25. YARDI R, Englot DJ, Wu C, Davis K, et al
    Emerging technologies and strategies in epilepsy surgery: toward personalised medicine.
    Lancet Neurol. 2026;25:77-89.
    PubMed         Abstract available


    Neurology

  26. CHENG CY, Lo SC, Huang CN, Yang YS, et al
    Association Between GLP-1 Receptor Agonist Use and Epilepsy Risk in Type 2 Diabetes.
    Neurology. 2026;106:e214509.
    PubMed         Abstract available

  27. KIM HK, Lee H, Choi SA, Lee HJ, et al
    Prenatal Exposure to Antiseizure Medications and the Risk of Congenital Anomalies: A Nationwide Population-Based Study in South Korea.
    Neurology. 2026;106:e214350.
    PubMed         Abstract available

  28. PARK PS, Chu DT, Bamford NS
    Clinical Reasoning: A 5-year-Old Boy With Subacute and Refractory Myoclonus.
    Neurology. 2026;106:e214457.
    PubMed         Abstract available


    Neuropediatrics

  29. GUNAY C, Binokay L, Karakulah G, Polat I, et al
    Exploring Molecular Pathways Underlying Epilepsy Development in Intellectual Disability.
    Neuropediatrics. 2025 Dec 11. doi: 10.1055/a-2768-3351.
    PubMed         Abstract available


    Pediatr Neurol

  30. ENYAMA D, Njinkui DN, Kengni Tefeu MF, Kouam JM, et al
    Clinical Profile of Pediatric Neurological Disorders at the Douala Gyneco-Obstetric and Pediatric Hospital in Cameroon.
    Pediatr Neurol. 2026;174:119-125.
    PubMed         Abstract available


    Pediatr Neurosurg

  31. DAS N, Mohamed AA, Katyayan A, Vessell M, et al
    Exploring Disparities in Pediatric Epilepsy Surgery.
    Pediatr Neurosurg. 2025 Dec 9:1-18. doi: 10.1159/000549985.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  32. JIANG X, Cai Z, Gonsisko C, Worrell GA, et al
    Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework.
    Proc Natl Acad Sci U S A. 2025;122:e2510015122.
    PubMed         Abstract available


    Seizure

  33. WANG Y, Li M, Huang X, Jiang P, et al
    Shared and divergent neuromagnetic network signatures in childhood absence epilepsy and self-limited epilepsy with centrotemporal spikes.
    Seizure. 2025;134:106-116.
    PubMed         Abstract available

  34. DILEK B, Berna SC, Olcay U, Deniz DD, et al
    Cardiac safety of low-dose ACTH therapy in infantile spasms: Evidence from electrocardiography and advanced echocardiography.
    Seizure. 2025;133:268-274.
    PubMed         Abstract available

  35. DEVI N, Soni P, Madaan P, Chaudhuri IR, et al
    Efficacy and safety of vigabatrin as preventive therapy for children with tuberous sclerosis complex: A systematic review and meta-analysis.
    Seizure. 2025;133:137-143.
    PubMed         Abstract available

  36. KONOMATSU K, Kakisaka Y, Ogawa M, Fujikawa M, et al
    Visualizing diagnostic delays in functional/dissociative seizures using the referral odyssey plot: A retrospective cohort study.
    Seizure. 2025;133:61-67.
    PubMed         Abstract available

  37. WU X, Chen L, Choe E, Heo K, et al
    Efficacy of adjunctive cenobamate by focal seizure subtypes: a randomized, double-blind, placebo-controlled, multicenter study in a multinational Asian population.
    Seizure. 2025;133:43-51.
    PubMed         Abstract available

  38. MELIKOVA S, Mammadbayli A
    Seizure control, delivery, and neonatal outcomes in pregnant women with focal epilepsies: a prospective cohort study.
    Seizure. 2025;134:117-125.
    PubMed         Abstract available

  39. STEINBART D, Geelhaar R, Lehmann R, Grimmer A, et al
    Cenobamate in adult patients with epilepsy and intellectual disability.
    Seizure. 2025;134:126-133.
    PubMed         Abstract available

  40. LACEY AS, Jones CB, Weir CJ, Stephen J, et al
    Educational attainment of children with self-limited epilepsy with CentroTemporal spikes (SELECTS), other epilepsies, and without epilepsy: A retrospective cohort study.
    Seizure. 2025;134:134-138.
    PubMed         Abstract available

  41. ZHOU M, Luo Y, Yang R, Zhang L, et al
    PIGA variants are associated with focal epilepsy with favorable outcome and the sub-molecular effect.
    Seizure. 2025;134:139-146.
    PubMed         Abstract available

  42. LI R, Wang C, Geng R, Xu X, et al
    Clinical and genetic analysis of epilepsy in children with SCN8A gene variants.
    Seizure. 2025;134:147-151.
    PubMed         Abstract available


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