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  Epilepsy

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03.11.2025

1 Ann Neurol
1 BMC Neurol
2 Brain
1 Dev Med Child Neurol
15 Epilepsia
1 Epilepsy Res
9 Epileptic Disord
1 J Neurol
1 J Neurosci
1 Neurol Educ
6 Neurology
1 Neuropediatrics
3 Pediatr Neurol
1 PLoS Med
7 Seizure


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Ann Neurol

  1. NGOH A, Clark M, Greenaway R, Chen X, et al
    Clinical and Molecular Genetic Characterization of Landau Kleffner Syndrome: An Observational Cohort and Experimental Study.
    Ann Neurol. 2025;98:951-966.
    PubMed         Abstract available


    BMC Neurol

  2. SAWAFTA R, Nazzal Z, Ashhab M, Nassar S, et al
    Clinical characteristics of pediatric epilepsy in Palestine: a cross-sectional study.
    BMC Neurol. 2025;25:447.
    PubMed         Abstract available


    Brain

  3. YE ZL, Li WB, Fan CX, Wang J, et al
    Reply: USP25 in genetic generalized epilepsy: a gene under scrutiny.
    Brain. 2025 Oct 27:awaf407. doi: 10.1093.
    PubMed        

  4. ERFANIAN OMIDVAR M, Murrell JR, Prentice AJ, Helbig I, et al
    USP25 in genetic generalized epilepsy: a gene under scrutiny.
    Brain. 2025 Oct 27:awaf406. doi: 10.1093.
    PubMed        


    Dev Med Child Neurol


  5. Personalized care of paediatric drug-resistant epilepsy in Africa: A single-centre pilot study utilizing mobile health and genetic testing.
    Dev Med Child Neurol. 2025 Oct 30. doi: 10.1111/dmcn.70075.
    PubMed        


    Epilepsia

  6. BADZIK S, Lin N
    Building bridges: One man's mission to bring hope to life with epilepsy.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18699.
    PubMed        

  7. VAN ARNHEM MML, Vijn LJ, Rubboli G, Khinchi MS, et al
    Clobazam versus corticosteroid for developmental and epileptic encephalopathy with spike-wave activation in sleep ((D)EE-SWAS): Results of a multicenter observational study.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18680.
    PubMed         Abstract available

  8. CAPUTO D, Solazzi R, Castellotti B, Panteghini C, et al
    Genetic complexity in pediatric onset epilepsy-movement disorder syndromes: Insights from a cohort of 97 subjects.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18669.
    PubMed         Abstract available

  9. KLEIN P, Aungaroon G, Biton V, Liow KK, et al
    Pharmacokinetics and tolerability of single-dose Staccato(R) alprazolam in adolescents with epilepsy, and population pharmacokinetic analysis to support dose selection in adolescents.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18643.
    PubMed         Abstract available

  10. DLUGOS DJ, Scheffer IE, French JA, Vossler DG, et al
    Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC).
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18689.
    PubMed         Abstract available

  11. ZHANG G, Lu Y, Xie L, Begemann A, et al
    De novo missense variants in BAIAP2 are associated with developmental and epileptic encephalopathies.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18661.
    PubMed         Abstract available

  12. NAZEM-ZADEH MR, Chang RS, Barnard S, Pardoe HR, et al
    Development and validation of clinico-imaging machine learning and deep learning models to predict responses to initial antiseizure medications in epilepsy.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18668.
    PubMed         Abstract available

  13. LE GAC F, Calonge Q, Estellat C, Navarro V, et al
    Comparing three natural language processing methods for the automatic identification of epilepsy patients from French clinical notes.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18683.
    PubMed         Abstract available

  14. PERRONE V, Veronesi C, Cappuccilli M, Andretta M, et al
    Characteristics, therapeutic pathway and the economic burden of patients with drug-resistant epilepsy: A real-world analysis following the introduction of cenobamate in Italy.
    Epilepsia. 2025 Oct 24. doi: 10.1111/epi.18673.
    PubMed         Abstract available

  15. SUN C, Spera R, Williamson JM, Joshi S, et al
    Respiratory dysfunction and fatal apnea during pilocarpine-induced status epilepticus.
    Epilepsia. 2025 Oct 25. doi: 10.1111/epi.18674.
    PubMed         Abstract available

  16. BALESTRINI S, Galli I, Ricci ML, Parrini E, et al
    Clinical and genetic landscape of epilepsies with absence seizures and single-gene etiology.
    Epilepsia. 2025 Oct 25. doi: 10.1111/epi.18655.
    PubMed         Abstract available

  17. NESTOR L, Van Den Herrewegen Y, Dyer M, Bossuyt J, et al
    Chemogenetic astrocyte modulation reduces spontaneous hippocampal discharges and metabolite changes in an epilepsy mouse model.
    Epilepsia. 2025 Oct 25. doi: 10.1111/epi.18684.
    PubMed         Abstract available

  18. LIANG XY, Meng XH, Wu WC, Guo J, et al
    De novo SRCAP variants cause developmental and epileptic encephalopathy and the phenotypic spectrum.
    Epilepsia. 2025 Oct 27. doi: 10.1111/epi.18695.
    PubMed         Abstract available

  19. HORINOUCHI T, Ishibashi H, Nakagami Y, Kobayashi Takahashi Y, et al
    Epilepsy in dentatorubral-pallidoluysian atrophy: A systematic review and meta-analysis.
    Epilepsia. 2025 Oct 28. doi: 10.1111/epi.18700.
    PubMed         Abstract available

  20. SINCLAIR B, Yasuda CL, Nicolo JP, Hlauschek G, et al
    Enlarged perivascular spaces in the basal ganglia across epilepsy subtypes.
    Epilepsia. 2025 Oct 29. doi: 10.1111/epi.18694.
    PubMed         Abstract available


    Epilepsy Res

  21. MARTINEZ BB, Portillo EA, Cabeza MM, Lobato ML, et al
    Effectiveness and tolerability of perampanel as first add-on treatment in pediatric patients with focal and generalized epilepsy.
    Epilepsy Res. 2025;218:107690.
    PubMed         Abstract available


    Epileptic Disord

  22. YUCEL G
    Comment on "Reduction of interictal epileptic burden by pulsatile corticoid therapy in children with drug-resistant epilepsy-How stable is the effect?".
    Epileptic Disord. 2025 Oct 30. doi: 10.1002/epd2.70125.
    PubMed        

  23. SCHILLER K, Avigdor T, Thomas J, Mansilla D, et al
    Response to the comment on: Reduction of interictal epileptic burden by pulsatile corticoid therapy in children with drug-resistant epilepsy-How stable is the effect?
    Epileptic Disord. 2025 Oct 30. doi: 10.1002/epd2.70119.
    PubMed        

  24. FEYS O, Bartolomei F
    Beyond the seizure "focus": Exploring the abscopal effect in focal epilepsy treatment.
    Epileptic Disord. 2025 Oct 28. doi: 10.1002/epd2.70124.
    PubMed        

  25. BERROCAL-IZQUIERDO N, Molina-Gonzalez P, Macau MA, Escrig-Avellaneda A, et al
    Abdominal clonic seizures: A rare form of vascular focal motor status epilepticus.
    Epileptic Disord. 2025 Oct 24. doi: 10.1002/epd2.70117.
    PubMed        

  26. POPHAL E, Taha M, Doll E, Nordli DR Jr, et al
    Sleep architecture and qEEG patterns in PME type 1 diagnosis.
    Epileptic Disord. 2025;27:1032-1037.
    PubMed         Abstract available

  27. ASIKOVALI M, Surmeli R, Yalcin AD
    Somatosensory evoked potentials in patients with typical absences.
    Epileptic Disord. 2025;27:911-918.
    PubMed         Abstract available

  28. NADARAJAH N, Fahey M, Seneviratne U
    Clinical characteristics associated with photoparoxysmal response in routine electroencephalography.
    Epileptic Disord. 2025;27:952-964.
    PubMed         Abstract available

  29. BRATU IF, El Youssef N, Lagarde S, Bartolomei F, et al
    Modulation of neural complexity and consciousness in temporal lobe seizures: Effects of high-frequency pulvinar stimulation.
    Epileptic Disord. 2025;27:1004-1010.
    PubMed         Abstract available

  30. HASKELL-MENDOZA AP, Ramani P, Dhoot R, Parikh P, et al
    Responsive neurostimulation detections: "Recognizing the unseen".
    Epileptic Disord. 2025;27:997-1003.
    PubMed         Abstract available


    J Neurol

  31. ZHOU H, Xu X
    Risk factors of recurrence for epilepsy patients after antiseizure medication withdrawal: what we do and do not know?
    J Neurol. 2025;272:726.
    PubMed         Abstract available


    J Neurosci

  32. ISAAC GUILLEN F, Geist MA, Cheng SY, Harris AM, et al
    A novel mouse model for developmental and epileptic encephalopathy by Purkinje cell-specific deletion of Scn1b.
    J Neurosci. 2025 Oct 29:e2184242025. doi: 10.1523/JNEUROSCI.2184-24.2025.
    PubMed         Abstract available


    Neurol Educ

  33. KIRKPATRICK L, Friel E, Clements M, Briscoe C, et al
    Education Research: How Child Neurologists Counsel About Reproductive Health and Epilepsy: Gaps in Accuracy and Clarity in an Educational Needs Assessment.
    Neurol Educ. 2025;4:e200261.
    PubMed         Abstract available


    Neurology

  34. FRENCH J, Greenwood HT, Kanner AM
    Author Response: Prevalence of Suicidality in Adolescents With Newly Diagnosed Focal Epilepsy at Diagnosis and Over the Following 36 Months.
    Neurology. 2025;105:e210293.
    PubMed        

  35. LIU J, Wang D, Xiao N
    Reader Response: Prevalence of Suicidality in Adolescents With Newly Diagnosed Focal Epilepsy at Diagnosis and Over the Following 36 Months.
    Neurology. 2025;105:e210135.
    PubMed        

  36. SIEGLER JE, Galetta SL
    Editors' Note: Prevalence of Suicidality in Adolescents With Newly Diagnosed Focal Epilepsy at Diagnosis and Over the Following 36 Months.
    Neurology. 2025;105:e214271.
    PubMed        

  37. NAGABHIRAVA RS, Zhou R, Pugh MJV, Towne AR, et al
    Differences in Mortality Between Veterans With Posttraumatic and Nontraumatic Epilepsy.
    Neurology. 2025;105:e214344.
    PubMed         Abstract available

  38. KRAUSS GL, Habela CW
    Deep Learning for the Prediction of Treatment Responses in Individuals With Epilepsy: Can We Get to Seizure Freedom Faster?
    Neurology. 2025;105:e214421.
    PubMed        

  39. FENG W, Nhu D, Anderson A, Thom D, et al
    Integrative Deep Learning of Genomic and Clinical Data for Predicting Treatment Response in Newly Diagnosed Epilepsy.
    Neurology. 2025;105:e214315.
    PubMed         Abstract available


    Neuropediatrics

  40. OBERLACK A, Wagner M
    Genetic Variants and Disease Mechanisms - Lessons from Monogenic Childhood Epilepsies.
    Neuropediatrics. 2025 Oct 27. doi: 10.1055/a-2731-5130.
    PubMed         Abstract available


    Pediatr Neurol

  41. BRISCOE C, Katyayan A, Harini C, Hussain SA, et al
    Treatment Practices for Infantile Epileptic Spasms Syndrome: Consensus and Variation in Major Pediatric Epilepsy Centers.
    Pediatr Neurol. 2025;174:46-53.
    PubMed         Abstract available

  42. WESTERGREN H, Hesla HM, Altman M, Freyland S, et al
    Epilepsy After Electroencephalographically Verified Neonatal Seizures: A Swedish Population-Based Matched Cohort Study.
    Pediatr Neurol. 2025;174:29-36.
    PubMed         Abstract available

  43. HACKETT AN, Yan H, Liu K, Corre C, et al
    Risk of Seizures and Epilepsy in the Leukodystrophies.
    Pediatr Neurol. 2025;174:20-28.
    PubMed         Abstract available


    PLoS Med

  44. OLALERE O, Tariq S, Ajijola O, Koh MD, et al
    Associations between epileptic seizures in pregnancy and adverse pregnancy outcomes: A systematic review and meta-analysis.
    PLoS Med. 2025;22:e1004580.
    PubMed         Abstract available


    Seizure

  45. ANNALISE W, Anita H, Judith D, Sereena R, et al
    Experiences of pregnancy and reproductive health for women living with epilepsy: A systematic review.
    Seizure. 2025;133:106-113.
    PubMed         Abstract available

  46. SARANTI A, Dragoumi P, Pavlogiannis K, Pavlou E, et al
    Efficacy and safety of cannabidiol in children with developmental and epileptic encephalopathies: A systematic review.
    Seizure. 2025;133:114-127.
    PubMed         Abstract available

  47. SARPDAGI Y, Kiraz M, Orun MO, Sir O, et al
    The role of psychological well-being in the effect of spirituality on stigma in individuals with epilepsy.
    Seizure. 2025;133:128-136.
    PubMed         Abstract available

  48. ZINGER JW, Rietdijk WJR, van den Berg S, Neuteboom RF, et al
    Ketogenic diet therapy enables antiseizure medication reduction and withdrawal in children with epilepsy.
    Seizure. 2025;133:144-148.
    PubMed         Abstract available

  49. KIMURA M, Togo M, Matoba K, Otani M, et al
    Relationship between cortical tuber subtypes and interictal epileptiform discharges in tuberous sclerosis complex: MRI and scalp-EEG study.
    Seizure. 2025;133:149-156.
    PubMed         Abstract available

  50. URBINA LOPEZ A, Varughese RT, Marti C, Ermekbaeva A, et al
    Fenfluramine treatment beyond dravet and lennox-gastaut syndromes - A retrospective study suggesting a novel use in genetic, developmental and epileptic encephalopathies (DEEs).
    Seizure. 2025;133:161-166.
    PubMed         Abstract available

  51. JUNG G, Lee J, Gho SM, Han Y, et al
    Predicting oxcarbazepine-induced hyponatremia in adult epilepsy patients: A multicenter machine learning analysis using real-world CDM data.
    Seizure. 2025;133:167-174.
    PubMed         Abstract available


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