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  Epilepsy

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16.03.2026

1 Ann Neurol
2 Brain
3 Brain Res
2 Curr Opin Neurol
16 Epilepsia
7 Epilepsy Res
17 Epileptic Disord
1 Int J Neurosci
1 J Neurol
1 J Neurol Neurosurg Psychiatry
1 J Neurol Sci
1 J Neurosci
7 Neurology
1 Neuropediatrics
2 Pediatr Neurol
1 PLoS One
1 Rev Neurol
22 Seizure


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Ann Neurol

  1. SCHEFFER IE, Perucca P, Karoly PJ
    Time to Change the Drug Trial Paradigm for Dravet Syndrome: Designing Trials for the Disease Rather than Squeezing the Disease into the Trial.
    Ann Neurol. 2026;99:792-795.
    PubMed         Abstract available


    Brain

  2. PRINA ML, Goyette AR, Abdulkareem AF, Tariq K, et al
    AKT is necessary for neuronal hypertrophy and epilepsy caused by Pten knockout.
    Brain. 2026 Mar 9:awag098. doi: 10.1093.
    PubMed         Abstract available

  3. AVALOS-ALAIS S, Jedynak M, Boyer A, Chanteloup-Foret B, et al
    High-resolution electrophysiological mapping of effective connectivity of lateral prefrontal cortex.
    Brain. 2026;149:963-975.
    PubMed         Abstract available


    Brain Res

  4. PATEL S, Mansuri M, Mehta I, Athalye M, et al
    Brain-targeted Brivaracetam delivery using mannose-functionalized mesoporous silica nanoparticles for the treatment of epilepsy.
    Brain Res. 2026;1880:150252.
    PubMed         Abstract available

  5. RANJBAR N, Raeisi M, Barzegar M, Ghorbanihaghjo A, et al
    The possible anti-seizure properties of Klotho.
    Brain Res. 2023;1820:148555.
    PubMed         Abstract available

  6. JOSE B, Gopinath S, Vijayanatha Kurup A, Nair M, et al
    Improving the accuracy of epileptogenic zone localization in stereo EEG with machine learning algorithms.
    Brain Res. 2023;1820:148546.
    PubMed         Abstract available


    Curr Opin Neurol

  7. RYVLIN P, Rheims S
    SUDEP update 2026: recent advances in experimental and clinical research.
    Curr Opin Neurol. 2026;39:123-130.
    PubMed         Abstract available

  8. PERUCCA P, Perucca E
    Novel pharmacological therapies in development.
    Curr Opin Neurol. 2026;39:138-149.
    PubMed         Abstract available


    Epilepsia

  9. LARSSON D, Mroue D, Andren K, Zelano J, et al
    Antiseizure medication selection and retention for adult onset focal epilepsy in a Swedish health service region: A population-based cohort study.
    Epilepsia. 2023;64:2617-2624.
    PubMed         Abstract available

  10. DELGADO-GARCIA G, Engbers JDT, Wiebe S, Mouches P, et al
    Machine learning using multimodal clinical, electroencephalographic, and magnetic resonance imaging data can predict incident depression in adults with epilepsy: A pilot study.
    Epilepsia. 2023;64:2781-2791.
    PubMed         Abstract available

  11. MOLISANI SE, Parikh D, DiGiovine M, Dlugos D, et al
    A quality improvement initiative to improve folic acid supplementation counseling for adolescent females with epilepsy.
    Epilepsia. 2023;64:2818-2826.
    PubMed         Abstract available

  12. BOLLING-LADEGAARD E, Dreier JW, Christensen J
    Identification of drug resistance in a validated cohort of incident epilepsy patients in the Danish National Patient Register.
    Epilepsia. 2023;64:2604-2616.
    PubMed         Abstract available

  13. CHANG BL, Liu JR, Chang SH, See LC, et al
    Impact on carbamazepine usage and cutaneous adverse reactions before and after the reimbursement of HLA-B*1502 genotyping in Taiwan, 2000-2017: A nationwide longitudinal study.
    Epilepsia. 2023;64:2679-2689.
    PubMed         Abstract available

  14. PELLINEN J, Pardoe H, Sillau S, Barnard S, et al
    Later onset focal epilepsy with roots in childhood: Evidence from early learning difficulty and brain volumes in the Human Epilepsy Project.
    Epilepsia. 2023;64:2761-2770.
    PubMed         Abstract available

  15. SULLIVAN J, Lagae L, Cross JH, Devinsky O, et al
    Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial.
    Epilepsia. 2023;64:2653-2666.
    PubMed         Abstract available

  16. TAYLOR PN, Hall G, Horsley J, Wang Y, et al
    Open diffusion magnetic resonance imaging and connectivity data for epilepsy and surgery: The IDEAS II release.
    Epilepsia. 2026 Mar 7. doi: 10.1002/epi.70186.
    PubMed         Abstract available

  17. HAUGER LE, Helmstaedter C, Lossius MI, Alfstad KA, et al
    Executive dysfunction and employment in epilepsy.
    Epilepsia. 2026 Mar 7. doi: 10.1002/epi.70165.
    PubMed         Abstract available

  18. KWON CS, Rafati A, Jette N, Newton CR, et al
    Validation of the International League Against Epilepsy (ILAE) Risk of Bias Tool against the Newcastle-Ottawa Scale in epilepsy research.
    Epilepsia. 2026 Mar 8. doi: 10.1002/epi.70183.
    PubMed         Abstract available

  19. ELLIS CA, Copeland J, Velez I, Oliver KL, et al
    Genetic testing for familial epilepsies: Diagnostic yield and genetic findings.
    Epilepsia. 2026 Mar 8. doi: 10.1002/epi.70160.
    PubMed         Abstract available

  20. DRANE DL, Willie JT, Dickey AS, Gross RE, et al
    Neuropsychological outcomes comparing traditional surgical approaches and laser interstitial therapy for refractory mesial temporal lobe epilepsy: A systematic review and meta-analysis.
    Epilepsia. 2026 Mar 9. doi: 10.1002/epi.70182.
    PubMed        

  21. STAVROGIANNI K, Tsalouchidou PE
    Response: Neuropsychological outcome in open resection and laser interstitial thermal therapy for mesial temporal lobe epilepsy: Meta-analysis and selective review.
    Epilepsia. 2026 Mar 9. doi: 10.1002/epi.70181.
    PubMed        

  22. BURLANDO G, Belforte C, Siebenhuhner F, Tullio LD, et al
    Unstable slow oscillations couple with epileptogenic fast-rhythm bistability in sleep-related epilepsy: A stereoelectroencephalographic study.
    Epilepsia. 2026 Mar 10. doi: 10.1002/epi.70188.
    PubMed         Abstract available

  23. WENG Y, Ma Y, Hou W, Li H, et al
    Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks.
    Epilepsia. 2026 Mar 13. doi: 10.1002/epi.70161.
    PubMed         Abstract available

  24. CHANG WC, Lin J, Cheung W, Lai A, et al
    Perturbation-induced responses improved seizure forecasting in epileptic rats.
    Epilepsia. 2026 Mar 13. doi: 10.1002/epi.70196.
    PubMed         Abstract available


    Epilepsy Res

  25. SUN L, Liu R, Han X, Wang N, et al
    Inflammation-mediated function enhancement of K(Na) channels promotes network hyperactivity in the peripheral cortex following TBI.
    Epilepsy Res. 2026;221:107751.
    PubMed         Abstract available

  26. MOASES GHAFFARY E, J Wyckoff G, Mirmosayyeb O
    Predicting seizure-free outcomes in people with treatment-resistant epilepsy: A machine learning approach.
    Epilepsy Res. 2026;223:107766.
    PubMed         Abstract available

  27. SANINOCENCIO C, Prince S, Chandran I, Simon EW, et al
    CHD2-related disorders: A conceptual disease model informed by caregiver experience.
    Epilepsy Res. 2026;221:107735.
    PubMed         Abstract available

  28. VONCK K, Verner R, Ranuzzi G, Patel R, et al
    Assessing an fMRI-guided titration paradigm for microburst VNS therapy.
    Epilepsy Res. 2026;221:107734.
    PubMed         Abstract available

  29. SAKAGUCHI Y, Seki H, Iwasaki Y, Kosho T, et al
    Risk factors of epilepsy severity in institutionalized adults with profound intellectual and multiple disabilities from childhood.
    Epilepsy Res. 2026;223:107768.
    PubMed         Abstract available

  30. STASENKO A, Schadler AJ, Kaestner E, Smith CN, et al
    Face-name associative memory in temporal lobe epilepsy: Region-specific insights in right-hemisphere onset.
    Epilepsy Res. 2026;223:107767.
    PubMed         Abstract available

  31. COPPOLA A, Moore-Ramdin L, Navetta M, Samanta D, et al
    Corrigendum to "A systematic review of highly purified cannabidiol in developmental and epileptic encephalopathies and complex treatment-resistant epilepsies: Changes in seizure frequency and adverse events" [Epilepsy Res. 220 (2026) 1-1/107731].
    Epilepsy Res. 2026 Mar 11:107777. doi: 10.1016/j.eplepsyres.2026.107777.
    PubMed        


    Epileptic Disord

  32. KANESAKI H, Watanabe K, Osugi K, Ohara H, et al
    Utility of scratch art therapy in adult epilepsy patients with difficulties in social adaptation.
    Epileptic Disord. 2023;25:702-711.
    PubMed         Abstract available

  33. NORDLI DR 3RD, Beier AD, Galan FN
    When in doubt, return to fundamentals (seizure semiology).
    Epileptic Disord. 2023;25:769-778.
    PubMed         Abstract available

  34. BALLARA PETITBO M, Gonzalez Alguacil E, Gutierrez Delicado E, Ortiz Cabrera NV, et al
    Neuropsychiatric comorbidities and cognition in epilepsy with eyelid myoclonia: A retrospective pediatric case series.
    Epileptic Disord. 2023;25:758-768.
    PubMed         Abstract available

  35. CUI Z, Wang J, Mao Z, Ling Z, et al
    Long-term efficacy of deep brain stimulation of the subthalamic nucleus in patients with pharmacologically intractable epilepsy: A case series of six patients.
    Epileptic Disord. 2023;25:712-723.
    PubMed         Abstract available

  36. HASEGAWA N, Annaka H
    Long-term effect associated with seizures and dynamic effect associated with treatment on cognitive dysfunction of adult patients with focal epilepsy as evaluated by the Trail Making Test.
    Epileptic Disord. 2023;25:731-738.
    PubMed         Abstract available

  37. PINTO GMDMMF, Fidalski SZK, Santos MLSF, de Souza J, et al
    Predictive factors of genetic diagnosis and real-life impact of next-generation sequencing for children with epilepsy.
    Epileptic Disord. 2023;25:724-730.
    PubMed         Abstract available

  38. ZHANG H, Yan L, Peng X, Jiang L, et al
    The prospective study of 54 children with electrical status epilepticus during sleep: How to simplify the electroencephalogram diagnosis and guide the treatment.
    Epileptic Disord. 2023;25:690-701.
    PubMed         Abstract available

  39. BATISTA C, Soares JI, Coelho P, Ferreira S, et al
    Closing the temporal blind spot: Six additional electrodes increase patient-level EEG abnormality detection by ~12.
    Epileptic Disord. 2026;28:97-108.
    PubMed         Abstract available

  40. DELGADO-MARTINEZ O, Paredes-Aragon E, Epitacio Neri B, Macias-Lopez J, et al
    The relationship of neuropsychiatric comorbidities and peri-ictal neuropsychiatric symptoms with readmission due to breakthrough seizures.
    Epileptic Disord. 2026;28:43-54.
    PubMed         Abstract available

  41. GILANI K, Fields M, Bolden D, Davitz M, et al
    Striatal stimulation causing movements mimicking faciobrachial dystonic seizures.
    Epileptic Disord. 2026;28:165-170.
    PubMed         Abstract available

  42. RODRIGUES TP, Bocca LF, Yacubian EMT, Guaranha MSB, et al
    Long-term predictors of seizure outcome after anterior temporal lobectomy in unilateral hippocampal sclerosis: A 281-patient cohort with mean 10-year follow-up.
    Epileptic Disord. 2026;28:84-96.
    PubMed         Abstract available

  43. KALAMPOKINI S, Pityrigkas E, Liouta E, Pepe G, et al
    Epilepsy characteristics in patients with muscle-eye-brain disease: A systematic review of electroclinical features.
    Epileptic Disord. 2026 Mar 7. doi: 10.1002/epd2.70217.
    PubMed         Abstract available

  44. KAYA E, Benli S, Keti DB, Kog C, et al
    Evaluation of serum irisin and meteorin-like (METRNL) levels in people with drug-resistant and drug-responsive temporal lobe epilepsy.
    Epileptic Disord. 2026 Mar 8. doi: 10.1002/epd2.70212.
    PubMed         Abstract available

  45. ROMERO CARVAJAL F, Moreira Holguin JC, YanezOrtiz E, Albuja AC, et al
    The "cat's paw sign": An ictal oro-palmo-facial automatism in a patient with non-dominant mesial temporal lobe epilepsy.
    Epileptic Disord. 2026 Mar 8. doi: 10.1002/epd2.70216.
    PubMed        

  46. TOMSON T, Zelano J, Dang YL, Perucca P, et al
    The pharmacological treatment of epilepsy in adults.
    Epileptic Disord. 2023;25:649-669.
    PubMed         Abstract available

  47. YIN F, Yan X, Gao R, Ren Z, et al
    Radiomics features from 3D-MPRAGE imaging can differentiate temporal-plus epilepsy from temporal lobe epilepsy.
    Epileptic Disord. 2023;25:681-689.
    PubMed         Abstract available

  48. AMIN U, Nascimento FA, Karakis I, Schomer D, et al
    Normal variants and artifacts: Importance in EEG interpretation.
    Epileptic Disord. 2023;25:591-648.
    PubMed         Abstract available


    Int J Neurosci

  49. BANO A, Nidhi, Samim M, Khan MA, et al
    Modulation of the HMGB1/TLR4 pathway by montelukast in PTZ-induced epilepsy: alleviating neuroinflammatory oxidative stress and seizure severity.
    Int J Neurosci. 2026 Mar 12:1-15. doi: 10.1080/00207454.2026.2633644.
    PubMed         Abstract available


    J Neurol

  50. TAILBY C, Chapman J, Helmstaedter C, Haderlein J, et al
    Telehealth enabled neuropsychological testing (TENT): a new platform for examiner-led, digital cognitive assessment.
    J Neurol. 2026;273:192.
    PubMed         Abstract available


    J Neurol Neurosurg Psychiatry

  51. VAKRINOU A, Bellampalli R, Gulcebi MI, Martins Custodio H, et al
    Risk-conferring HLA variants in an epilepsy cohort: benefits of multifaceted use of whole genome sequencing in clinical practice.
    J Neurol Neurosurg Psychiatry. 2023;94:887-892.
    PubMed         Abstract available


    J Neurol Sci

  52. PENA-CEBALLOS J, Moloney PB, Kinney MO, Mullins G, et al
    How are we doing? The electroclinical diagnosis of status epilepticus in idiopathic generalized epilepsy in a tertiary referral center: A case series and scoping review of 40 years of literature.
    J Neurol Sci. 2026;484:125864.
    PubMed         Abstract available


    J Neurosci

  53. HOLMES-LEON G, Li N, Albrecht J, Newkirk GS, et al
    Suppression of in vitro epileptiform activity by GABA transaminase inhibition is dependent on GABA(B) receptors and GABA transporter type 1 (GAT1).
    J Neurosci. 2026 Mar 12:e1075252026. doi: 10.1523/JNEUROSCI.1075-25.2026.
    PubMed         Abstract available


    Neurology

  54. ZHANG LB, Wu YY, Qiu DJ, Li WB, et al
    Child Neurology: Multiple Genetic Etiologies Causing Dandy-Walker Variant With Microcephaly, Epilepsy, and Global Developmental Delay.
    Neurology. 2026;106:e214793.
    PubMed         Abstract available

  55. BERG AT
    Respiratory Variability and Sudden Unexpected Death in Epilepsy: Could It Identify Patients at Greatest Risk?
    Neurology. 2026;106:e214838.
    PubMed        

  56. CAPLAN J, Vilella L, Lee P, Nair R, et al
    Association of Interictal Respiratory Variability and Severity of Postictal Hypoxemia After Generalized Convulsive Seizures.
    Neurology. 2026;106:e214749.
    PubMed         Abstract available

  57. BENISH SM, Friedman D, Merchant S, Minen MT, et al
    Wearable Technology and Its Role in Neurologic Care: Emerging Issues in Neurology.
    Neurology. 2026;106:e214802.
    PubMed         Abstract available

  58. SANDS TT
    Early Electroclinical Phenotypes of Genetic Epilepsies Identified Through Unsupervised Machine Learning: AI in the House of Gastaut.
    Neurology. 2026;106:e214884.
    PubMed        

  59. DE DOMINICIS A, Mercier M, Carfi Pavia G, Piscitello LM, et al
    Early Clinical and EEG Association of Genotype and Outcome in Genetic Epilepsies: A Cohort Study and Hierarchical Clustering Analysis.
    Neurology. 2026;106:e214761.
    PubMed         Abstract available

  60. COHEN NT, Li X, Berl MM, Oluigbo CO, et al
    International Consensus on the Evaluation and Management of Hypothalamic Hamartomas: Results From a Modified Delphi Survey.
    Neurology. 2026;106:e214760.
    PubMed         Abstract available


    Neuropediatrics

  61. KOKER A, Donbaloglu F, Cebisli E, Ulgen Tekerek N, et al
    Utility and Prognostic Implications of Continuous Electroencephalogram Monitoring in Pediatric Intensive Care.
    Neuropediatrics. 2026;57:100-106.
    PubMed         Abstract available


    Pediatr Neurol

  62. GUBERMAN G, Scala M, Striano P, Zara F, et al
    Biallelic Rare COL18A1 Variants in Patients With Neurological Phenotypes Without Severe Ophthalmologic Abnormalities.
    Pediatr Neurol. 2026;176:64-67.
    PubMed         Abstract available

  63. ANCORA C, Marchi M, Bonardi CM, Sartori G, et al
    Electroclinical Features in Two Novel STRADA Patients and a Functional Yeast Assay for the Validation of Missense STRADA Mutations.
    Pediatr Neurol. 2023;148:152-156.
    PubMed         Abstract available


    PLoS One

  64. SUN Y, Chen X, Zhang X, Cai X, et al
    Research on epilepsy detection methods based on interpretable features and machine learning.
    PLoS One. 2026;21:e0344164.
    PubMed         Abstract available


    Rev Neurol

  65. DE CASTRO AC, Garcia-Rubio MJ
    Cognitive, Behavioral, and Emotional Manifestations in Nodding Syndrome: A Neuropsychological Narrative Review.
    Rev Neurol. 2026;81:47379.
    PubMed         Abstract available


    Seizure

  66. INOUE T, Otsubo H, Kuki I, Yamamoto N, et al
    Clinical characteristics and treatment outcomes of epileptic spasms: Comparative analysis of 277 patients by age at onset (<1 year, 1-2 years, >2 years).
    Seizure. 2026;137:91-99.
    PubMed         Abstract available

  67. FINSTERER J
    Before status epilepticus in epilepsy patients is attributed to the SARS-CoV-2 vaccination, alternative causes must be ruled out: Status epilepticus after COVID-19 vaccination.
    Seizure. 2026;136:119-120.
    PubMed        

  68. DANA BB, Ivana M, Jiri K, Adela O, et al
    How accurately do adults judge children with epilepsy? A multi-informant perspective on quality of life and child characteristics.
    Seizure. 2026;137:74-80.
    PubMed         Abstract available

  69. WAN L, Cao X, Wang W, Li Z, et al
    Efficacy and tolerability of early assessment of epileptic spasms to guide sequential treatment in children with infantile epileptic spasms syndrome:A nested case-control Study.
    Seizure. 2026;137:62-70.
    PubMed         Abstract available

  70. DAWOUD B, O Boyle R, John D, Santos AN, et al
    Thalamic stimulation for drug-resistant focal epilepsy: a case report and focused literature review of RNS lead revision.
    Seizure. 2026;137:53-61.
    PubMed         Abstract available

  71. HLAUSCHEK G, Sinclair B, Sodal HF, Tauboll E, et al
    Are enlarged perivascular spaces a predictor of early post-traumatic seizures after traumatic brain injury?- A pilot study.
    Seizure. 2026;136:86-92.
    PubMed         Abstract available

  72. VAJDA FJE, O'Brien TJ, Graham JE, Hitchcock AE, et al
    Lamotrigine as an antiseizure medication in pregnancy.
    Seizure. 2026;136:18-22.
    PubMed         Abstract available

  73. LEE SH, Gillespie C, Bandyopadhyay S, Nazari A, et al
    National audit of pathways in epileptic seizure referrals (NAPIER): A national, multicentre audit of first seizure clinics throughout the UK and Ireland.
    Seizure. 2023;111:165-171.
    PubMed         Abstract available

  74. LIU W, Zhang H, Wang P, Zhang E, et al
    First add-on lacosamide treatment in children with focal epilepsy in China: A multi-centre real-life cohort study.
    Seizure. 2023;111:158-163.
    PubMed         Abstract available

  75. SERRAND C, Faucanie M, Jaussent A, Crespel A, et al
    How valid are proxy assessment of mental health and sleep comorbidities of patients with epilepsy using standardized questionnaires?
    Seizure. 2023;111:151-157.
    PubMed         Abstract available

  76. MANOKARAN RK, Yau I, Whitney R, Ochi A, et al
    Contralateral hippocampal sclerosis following functional hemispherectomy in children: A report of three cases.
    Seizure. 2023;111:147-150.
    PubMed         Abstract available

  77. LI W, Jiang Y, Li X, Huang H, et al
    More extensive structural damage in temporal lobe epilepsy with hippocampal sclerosis type 1.
    Seizure. 2023;111:130-137.
    PubMed         Abstract available

  78. WU X, Zhong S, Cai Y, Yang Y, et al
    Heterozygous RELN missense variants associated with genetic generalized epilepsy.
    Seizure. 2023;111:122-129.
    PubMed         Abstract available

  79. ARIDA RM, Teixeira-Machado L
    Physical exercise for children and adolescents with epilepsy: What have we learned?
    Seizure. 2023;111:1-8.
    PubMed         Abstract available

  80. SANTOS AN, Rauschenbach L, Riess C, Georgiades I, et al
    Outcome after conservative or surgical treatment for new-onset epilepsy in children with cerebral cavernous malformation.
    Seizure. 2023;111:23-29.
    PubMed         Abstract available

  81. HAM AS, Traore M, Othon GC, Conde ML, et al
    Improvement in health perception but not quality of life with an antiseizure medication intervention in people with epilepsy in Guinea: A cohort study.
    Seizure. 2023;111:30-35.
    PubMed         Abstract available

  82. VICINO W, Muccioli L, Pondrelli F, Licchetta L, et al
    Real-world experience with cannabidiol as add-on treatment in drug-resistant epilepsy.
    Seizure. 2023;111:39-41.
    PubMed         Abstract available

  83. COUTINHO MP, Faustino P, Ladeira F, Leitao L, et al
    Hypophosphatemia as a possible biomarker for epileptic seizures at the emergency department.
    Seizure. 2023;111:42-44.
    PubMed         Abstract available

  84. ALSUKHNI RA, Johnson J, Nashef L
    Valproate-induced reversible cognitive decline presenting as dementia and associated clinical features: A literature review.
    Seizure. 2023;111:45-50.
    PubMed         Abstract available

  85. AMENGUAL-GUAL M, Sanchez Fernandez I, Vasquez A, Abend NS, et al
    Pediatric status epilepticus management by Emergency Medical Services (the pSERG cohort).
    Seizure. 2023;111:51-55.
    PubMed         Abstract available

  86. YANG TW, Kim YS, Kim DH, Yeom JS, et al
    Felt stigma proportion in people living with epilepsy: A systematic review.
    Seizure. 2023;111:87-97.
    PubMed         Abstract available

  87. JINDAL M, Neligan A, Rajakulendran S
    Early and established status epilepticus: The impact of timing of intervention, treatment escalation and dosing on outcome.
    Seizure. 2023;111:98-102.
    PubMed         Abstract available


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