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Epilepsy

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Articles published in Epilepsia
Retrieve available abstracts of 1077 articles:
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Single Articles

December 2024

NICO ENSLIN JM, Muh CR, Wang X, von Hertwig Fernandes de Olivera T, et al
Epilepsy surgery education and practice around the globe: An ILAE taskforce report.
Epilepsia. 2024 Dec 5. doi: 10.1111/epi.18199.
PubMed Abstract available

TAYLOR PN, Wang Y, Simpson C, Janiukstyte V, et al
The Imaging Database for Epilepsy And Surgery (IDEAS).
Epilepsia. 2024 Dec 5. doi: 10.1111/epi.18192.
PubMed Abstract available

WOLF P, Hein D
Did Joseph Conrad have juvenile myoclonic epilepsy?
Epilepsia. 2024 Dec 5. doi: 10.1111/epi.18206.
PubMed Abstract available

MILLS J, Romagnolo A, Battaglia G, Eyal S, et al
Exploring the impact of climate change on epilepsy: Insights from the 15th European Epilepsy Congress.
Epilepsia. 2024 Dec 5. doi: 10.1111/epi.18208.
PubMed

LEE DA, Lee HJ, Kim SE, Park KM, et al
Peak width of skeletonized mean diffusivity as a marker of small vessel disease in patients with temporal lobe epilepsy with hippocampal sclerosis.
Epilepsia. 2024 Dec 5. doi: 10.1111/epi.18205.
PubMed Abstract available

KUDR M, Janca R, Jahodova A, Belohlavkova A, et al
Epilepsy surgery in children with operculoinsular epilepsy: Results of a large unicentric cohort.
Epilepsia. 2024 Dec 5. doi: 10.1111/epi.18185.
PubMed Abstract available

November 2024

BEUCHAT I, Novy J, Alvarez V, Rosenow F, et al
Association of early general anesthesia with outcome in adults with status epilepticus: A propensity-matched observational study.
Epilepsia. 2024 Nov 28. doi: 10.1111/epi.18203.
PubMed Abstract available

EBERHARD J, Henning L, Fulle L, Knopper K, et al
Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy.
Epilepsia. 2024 Nov 28. doi: 10.1111/epi.18200.
PubMed Abstract available

DE CURTIS M, Asukile M, Battaglia G, Sellin A, et al
Basic and preclinical epilepsy research Scientists' perception of clinical epileptology.
Epilepsia. 2024 Nov 28. doi: 10.1111/epi.18186.
PubMed Abstract available

BARRIOS-MARTINEZ JV, Almast A, Lin I, Youssef A, et al
Structural connectivity changes in focal epilepsy: Beyond the epileptogenic zone.
Epilepsia. 2024 Nov 22. doi: 10.1111/epi.18175.
PubMed Abstract available

CASILLAS-ESPINOSA PM, Wong JC, Grabon W, Gonzalez-Ramos A, et al
WONOEP appraisal: Targeted therapy development for early onset epilepsies.
Epilepsia. 2024 Nov 19. doi: 10.1111/epi.18187.
PubMed Abstract available

WHEELER L, Kremen V, Mersereau C, Ornelas G, et al
Automatic responsiveness testing in epilepsy with wearable technology: The ARTiE Watch.
Epilepsia. 2024 Nov 19. doi: 10.1111/epi.18181.
PubMed Abstract available

STEFANIDOU M, Himali JJ, Bernal R, Satizabal C, et al
Association of cognitive and structural correlates of brain aging and incident epilepsy. The Framingham Heart Study.
Epilepsia. 2024 Nov 18. doi: 10.1111/epi.18160.
PubMed Abstract available

PERUCCA P, Battino D, Bromley R, Chen L, et al
Epilepsy-pregnancy registries: An update.
Epilepsia. 2024 Nov 14. doi: 10.1111/epi.18180.
PubMed Abstract available

BRUCKHAUS AA, Asifriyaz T, Kriukova K, O'Brien TJ, et al
Exploring multimodal biomarker candidates of post-traumatic epilepsy following moderate to severe traumatic brain injury: A systematic review and meta-analysis.
Epilepsia. 2024 Nov 12. doi: 10.1111/epi.18131.
PubMed Abstract available

YIP KL, Udoh M, Sharman LA, Harman T, et al
Cannabinoid-like compounds found in non-cannabis plants exhibit antiseizure activity in genetic mouse models of drug-resistant epilepsy.
Epilepsia. 2024 Nov 12. doi: 10.1111/epi.18177.
PubMed Abstract available

CHANG BL, Walker MC, Kullmann DM, Schorge S, et al
Deciphering temporal gene expression dynamics during epilepsy development using a rat model of focal neocortical epilepsy.
Epilepsia. 2024 Nov 11. doi: 10.1111/epi.18169.
PubMed Abstract available

NABBOUT R, Molimard A, Scorrano G, Aubart M, et al
Transition from pediatric to adult care system in patients with complex epilepsies: Necker model for transition evaluated on 70 consecutive patients.
Epilepsia. 2024 Nov 11. doi: 10.1111/epi.18178.
PubMed Abstract available

WANG YY, Ma L, Shi XJ, Liu Y, et al
Cerebellar transcranial magnetic stimulation to treat drug-resistant epilepsy: A randomized, controlled, crossover clinical trial.
Epilepsia. 2024 Nov 8. doi: 10.1111/epi.18168.
PubMed Abstract available

WAINBERG RC, Martins WA, de Oliveira FH, Paglioli E, et al
Histopathological substrate of increased T2 signal in the anterior temporal lobe white matter in temporal lobe epilepsy associated with hippocampal sclerosis.
Epilepsia. 2024 Nov 6. doi: 10.1111/epi.18162.
PubMed Abstract available

CAFRI N, Mirloo S, Zarhin D, Kamintsky L, et al
Imaging blood-brain barrier dysfunction in drug-resistant epilepsy: A multi-center feasibility study.
Epilepsia. 2024 Nov 6. doi: 10.1111/epi.18145.
PubMed Abstract available

PUGH MJ, Munger Clary H, Myers M, Kennedy E, et al
Distinct comorbidity phenotypes among post-9/11 Veterans with epilepsy are linked to diverging outcomes and mortality risks.
Epilepsia. 2024 Nov 2. doi: 10.1111/epi.18170.
PubMed Abstract available

STRUCK AF, Garcia-Ramos C, Prabhakaran V, Nair V, et al
Latent cognitive phenotypes in juvenile myoclonic epilepsy: Clinical, sociodemographic, and neuroimaging associations.
Epilepsia. 2024 Nov 2. doi: 10.1111/epi.18167.
PubMed Abstract available

HACK JB, Watkins JC, Schreiber JM, Hammer MF, et al
Patients carrying pathogenic SCN8A variants with loss- and gain-of-function effects can be classified into five subgroups exhibiting varying developmental and epileptic components of encephalopathy.
Epilepsia. 2024;65:3324-3334.
PubMed Abstract available

FU Y, Shi F, Sha L, Yang X, et al
Effects of antiseizure medication withdrawal during the first trimester of pregnancy on seizure control and offspring outcomes.
Epilepsia. 2024;65:3186-3198.
PubMed Abstract available

ZHANG B, Chen WV, Regalia G, Goldenholz DM, et al
Statistical characteristics of large-scale objective tonic-clonic seizure records from medical smartwatches used in daily life.
Epilepsia. 2024;65:3255-3264.
PubMed Abstract available

HINCHLIFFE CHL, Yogarajah M, Elkommos S, Tang H, et al
Nonictal electroencephalographic measures for the diagnosis of functional seizures.
Epilepsia. 2024;65:3293-3302.
PubMed Abstract available

Special Issue: European Epilepsy Congress Abstract Issue.
Epilepsia. 2024;65 Suppl 1:1-508.
PubMed

October 2024

KAYABAS MA, Koksal Ersoz E, Yochum M, Bartolomei F, et al
Transition to seizure in focal epilepsy: From SEEG phenomenology to underlying mechanisms.
Epilepsia. 2024 Oct 30. doi: 10.1111/epi.18173.
PubMed Abstract available

BAUER T, Olbrich S, Groteklaes A, Lehnen NC, et al
Proof of concept: Portable ultra-low-field magnetic resonance imaging for the diagnosis of epileptogenic brain pathologies.
Epilepsia. 2024 Oct 29. doi: 10.1111/epi.18171.
PubMed Abstract available

SANDERS MWCB, Koeleman BPC, Brilstra EH, Jansen FE, et al
Somatic variant analysis of resected brain tissue in epilepsy surgery patients.
Epilepsia. 2024 Oct 26. doi: 10.1111/epi.18148.
PubMed Abstract available

YOON H, Ringland A, Anderson JJ, Sran S, et al
Mouse models of Slc35a2 brain mosaicism reveal mechanisms of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy.
Epilepsia. 2024 Oct 26. doi: 10.1111/epi.18166.
PubMed Abstract available

COHEN H, Bahash N, Raccah B, Matok I, et al
The level is in the details: Why differences between direct-acting oral anticoagulants should be considered in the treatment of patients with epilepsy.
Epilepsia. 2024 Oct 26. doi: 10.1111/epi.18144.
PubMed

MONTANUCCI L, Brunger T, Bosselmann CM, Ivaniuk A, et al
Evaluating novel in silico tools for accurate pathogenicity classification in epilepsy-associated genetic missense variants.
Epilepsia. 2024 Oct 23. doi: 10.1111/epi.18155.
PubMed Abstract available

ARORA A, Prakash P, Rizzo L, Blackman G, et al
Effectiveness of antipsychotic drug therapy for treating psychosis in people with epilepsy: A systematic review.
Epilepsia. 2024 Oct 21. doi: 10.1111/epi.18123.
PubMed Abstract available

Correction to "New onset refractory status epilepticus: Summary of the NORSE Institute roundtable during the 2023 American Epilepsy Society meeting, Orlando, Florida".
Epilepsia. 2024 Oct 21. doi: 10.1111/epi.18040.
PubMed

PAKALAPATI N, Chiang CC, Durand DM
Low-frequency stimulation of corpus callosum suppresses epileptiform activity in the cortex through gamma-aminobutyric acid type B receptor and slow afterhyperpolarization-mediated reduction in tissue excitability.
Epilepsia. 2024 Oct 19. doi: 10.1111/epi.18135.
PubMed Abstract available

CLIFFORD HJ, Paranathala MP, Wang Y, Thomas RH, et al
Vagus nerve stimulation for epilepsy: A narrative review of factors predictive of response.
Epilepsia. 2024 Oct 16. doi: 10.1111/epi.18153.
PubMed Abstract available

MU C, Kesler M, Chen X, Shearer J, et al
Exogenous ketones exert antiseizure effects and modulate the gut microbiome and mycobiome in a clinically relevant murine model of epilepsy.
Epilepsia. 2024 Oct 16. doi: 10.1111/epi.18150.
PubMed Abstract available

CHOI H, Thacker EL, Liu M, Strobino K, et al
Racial/ethnic differences in the association of incident stroke with late onset epilepsy: The Northern Manhattan Study.
Epilepsia. 2024 Oct 15. doi: 10.1111/epi.18156.
PubMed Abstract available

KATYAYAN A, Lee ST, Martinez L, Takacs DS, et al
Characteristics of overnight video-EEG monitoring in infantile epileptic spasms syndrome at 2-week follow-up.
Epilepsia. 2024 Oct 15. doi: 10.1111/epi.18143.
PubMed Abstract available

FONSECA E, Lallana S, Ortega G, Cano A, et al
Amyloid deposition in adults with drug-resistant temporal lobe epilepsy.
Epilepsia. 2024 Oct 15. doi: 10.1111/epi.18142.
PubMed Abstract available

CASES-CUNILLERA S, Quatraccioni A, Rossini L, Ruffolo G, et al
WONOEP appraisal: The role of glial cells in focal malformations associated with early onset epilepsies.
Epilepsia. 2024 Oct 14. doi: 10.1111/epi.18126.
PubMed Abstract available

HEISKANEN M, Banuelos I, Manninen E, Andrade P, et al
Plasma neurofilament heavy chain is a prognostic biomarker for the development of severe epilepsy after experimental traumatic brain injury.
Epilepsia. 2024 Oct 14. doi: 10.1111/epi.18149.
PubMed Abstract available

VAN PATTEN R, Blum A, Correia S, Philip NS, et al
One-year follow-up of neurobehavioral therapy in functional seizures or epilepsy with traumatic brain injury: A nonrandomized controlled trial.
Epilepsia. 2024 Oct 10. doi: 10.1111/epi.18137.
PubMed Abstract available

LEDA M, Puka K, Bax K, Gagnier JJ, et al
Establishing the minimum clinically important difference of the Quality of Life in Childhood Epilepsy Questionnaire.
Epilepsia. 2024 Oct 9. doi: 10.1111/epi.18140.
PubMed Abstract available

STAUNER L, Bao H, Delazer L, Kirsch I, et al
Longitudinal evaluation of retinal neuroaxonal loss in epilepsy using optical coherence tomography.
Epilepsia. 2024 Oct 9. doi: 10.1111/epi.18139.
PubMed Abstract available

BOTTCHER S, Zabler N, Jackson M, Bruno E, et al
Effects of epileptic seizures on the quality of biosignals recorded from wearables.
Epilepsia. 2024 Oct 7. doi: 10.1111/epi.18138.
PubMed Abstract available

ARIMORO OI, Wiebe S, Lin CQY, Josephson CB, et al
Health utilities of patients with epilepsy in a Canadian population.
Epilepsia. 2024 Oct 7. doi: 10.1111/epi.18132.
PubMed Abstract available

CAGNOLI C, De Santis D, Caccia C, Bongarzone I, et al
Matrix-assisted laser desorption/ionization mass spectrometry imaging as a new tool for molecular histopathology in epilepsy surgery.
Epilepsia. 2024 Oct 5. doi: 10.1111/epi.18136.
PubMed Abstract available

VAN VLIET EA, Scheper M, Mills JD, Puhakka N, et al
Circulating microRNAs and isomiRs as biomarkers for the initial insult and epileptogenesis in four experimental epilepsy models: The EPITARGET study.
Epilepsia. 2024 Oct 1. doi: 10.1111/epi.18134.
PubMed Abstract available

ABI TAYEH R, Dozieres-Puyravel B, Arnaud L, Titomanlio L, et al
Pharmacological management of prolonged seizures in Dravet syndrome including intravenous phenytoin.
Epilepsia. 2024;65:e175-e181.
PubMed Abstract available

MENSAH JA, Johnson K, Freeman T, Reilly CA, et al
Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome.
Epilepsia. 2024;65:3100-3114.
PubMed Abstract available

SALDARIS JM, Jacoby P, Downs J, Marsh ED, et al
Psychometric evaluation of clinician- and caregiver-reported clinical severity assessments for individuals with CDKL5 deficiency disorder.
Epilepsia. 2024;65:3064-3075.
PubMed Abstract available

MANSILLA D, Tveit J, Aurlien H, Avigdor T, et al
Generalizability of electroencephalographic interpretation using artificial intelligence: An external validation study.
Epilepsia. 2024;65:3028-3037.
PubMed Abstract available

ROBERTI R, Assenza G, Bisulli F, Boero G, et al
Adjunctive cenobamate in people with focal onset seizures: Insights from the Italian Expanded Access Program.
Epilepsia. 2024;65:2909-2922.
PubMed Abstract available

September 2024

SYMONDS JD, Park KL, Mignot C, Macleod S, et al
POLR3B is associated with a developmental and epileptic encephalopathy with myoclonic-atonic seizures and ataxia.
Epilepsia. 2024 Sep 30. doi: 10.1111/epi.18115.
PubMed Abstract available

BLANK LJ, Agarwal P, Kwon CS, Boockvar K, et al
Association of first antiseizure medication with acute health care utilization in a cohort of adults with newly diagnosed epilepsy.
Epilepsia. 2024 Sep 28. doi: 10.1111/epi.18133.
PubMed Abstract available

RUBBOLI G, Bo MH, Alfstad K, Armand Larsen S, et al
Clinical utility of ultra long-term subcutaneous electroencephalographic monitoring in drug-resistant epilepsies: a "real world" pilot study.
Epilepsia. 2024 Sep 28. doi: 10.1111/epi.18121.
PubMed Abstract available

VALENTE KD, Reilly C, Carvalho RM, Smith ML, et al
Consensus-based recommendations for the diagnosis and treatment of anxiety and depression in children and adolescents with epilepsy: A report from the Psychiatric Pediatric Issues Task Force of the International League Against Epilepsy.
Epilepsia. 2024 Sep 25. doi: 10.1111/epi.18116.
PubMed Abstract available

GONG R, Roth RW, Hull K, Rashid H, et al
Quantifying hubness to predict surgical outcomes in epilepsy: Assessing resection-hub alignment in interictal intracranial EEG networks.
Epilepsia. 2024 Sep 21. doi: 10.1111/epi.18128.
PubMed Abstract available

BERGLUND M, Gonzalez-Izquierdo A, Denaxas S, Lethebe BC, et al
Excess health care use is significantly and persistently reduced following diagnosis of late-onset epilepsy.
Epilepsia. 2024 Sep 20. doi: 10.1111/epi.18105.
PubMed Abstract available

ALI I, Jupp B, Hudson MR, Major B, et al
In vivo biomarkers of GABAergic function in epileptic rats treated with the GAT-1 inhibitor E2730.
Epilepsia. 2024 Sep 20. doi: 10.1111/epi.18119.
PubMed Abstract available

QUATRACCIONI A, Cases-Cunillera S, Balagura G, Coleman M, et al
WONOEP appraisal: Genetic insights into early onset epilepsies.
Epilepsia. 2024 Sep 20. doi: 10.1111/epi.18124.
PubMed Abstract available

SURDI P, Trivisano M, De Dominicis A, Mercier M, et al
Unveiling the disease progression in developmental and epileptic encephalopathies: Insights from EEG and neuropsychology.
Epilepsia. 2024 Sep 17. doi: 10.1111/epi.18127.
PubMed Abstract available

TSAI C, Taylor S, Thompson N, Vegh D, et al
Role of comorbidities in epilepsy surgery outcomes of older adults.
Epilepsia. 2024 Sep 16. doi: 10.1111/epi.18103.
PubMed Abstract available

PARK S, Permezel F, Agashe S, Osman G, et al
Centromedian thalamic deep brain stimulation for idiopathic generalized epilepsy: Connectivity and target optimization.
Epilepsia. 2024 Sep 14. doi: 10.1111/epi.18122.
PubMed Abstract available

ZHONG R, Li G, Zhao T, Zhang H, et al
Association of baseline sleep duration and sleep quality with seizure recurrence in newly treated patients with epilepsy.
Epilepsia. 2024 Sep 11. doi: 10.1111/epi.18106.
PubMed Abstract available

DEFELIPPE VM, Brilstra EH, Otte WM, Cross HJ, et al
N-of-1 trials in epilepsy: A systematic review and lessons paving the way forward.
Epilepsia. 2024 Sep 10. doi: 10.1111/epi.18068.
PubMed Abstract available

PROOST R, Cleeren E, Jansen B, Lagae L, et al
Factors associated with poor sleep in children with drug-resistant epilepsy.
Epilepsia. 2024 Sep 10. doi: 10.1111/epi.18112.
PubMed Abstract available

SUNG KL, Kuo MJ, Yang HY, Tsai CF, et al
Poststroke seizures and epilepsy increase the risk of dementia among stroke survivors: A population-based study.
Epilepsia. 2024 Sep 10. doi: 10.1111/epi.18117.
PubMed Abstract available

MELETTI S, Cuccurullo C, Orlandi N, Borzi G, et al
Prediction of epilepsy after stroke: Proposal of a modified SeLECT 2.0 score based on posttreatment stroke outcome.
Epilepsia. 2024 Sep 5. doi: 10.1111/epi.18114.
PubMed Abstract available

CENDES F
Introduction of the incoming editor-in-chief of Epilepsia.
Epilepsia. 2024 Sep 2. doi: 10.1111/epi.18084.
PubMed

SOURBRON J, Auvin S, Cabral-Lim L, Devlin A, et al
Vitamin D prophylaxis in persons with epilepsy?
Epilepsia. 2024;65:2567-2579.
PubMed Abstract available

SINGH V, Auerbach DS
Neurocardiac pathologies associated with potassium channelopathies.
Epilepsia. 2024;65:2537-2552.
PubMed Abstract available

DOSS DJ, Johnson GW, Makhoul GS, Rashingkar RV, et al
Network signatures define consciousness state during focal seizures.
Epilepsia. 2024;65:2686-2699.
PubMed Abstract available

PURNELL B, Bhasin J, Rust B, George S, et al
Disruption of adenosine metabolism increases risk of seizure-induced death despite decreased seizure severity.
Epilepsia. 2024;65:2798-2811.
PubMed Abstract available

FLEURY MN, Binding LP, Taylor P, Xiao F, et al
Predictors of long-term memory and network connectivity 10 years after anterior temporal lobe resection.
Epilepsia. 2024;65:2641-2661.
PubMed Abstract available

GASCOIGNE SJ, Evans N, Hall G, Kozma C, et al
Incomplete resection of the intracranial electroencephalographic seizure onset zone is not associated with postsurgical outcomes.
Epilepsia. 2024;65:e163-e169.
PubMed Abstract available

August 2024

NIELSEN SJ, Bech BH, Strandberg-Larsen K, Bolling-Ladegaard E, et al
Febrile seizures and childhood epilepsy and risk of internalizing and psychotic symptoms.
Epilepsia. 2024 Aug 31. doi: 10.1111/epi.18095.
PubMed Abstract available

TONG X, Wang Q, Yang J, Zhou J, et al
Optimizing ketogenic diet therapy for childhood epilepsy: Identifying key factors for seizure control and psychomotor enhancement.
Epilepsia. 2024 Aug 27. doi: 10.1111/epi.18098.
PubMed Abstract available

LATREILLE V, Corbin-Lapointe J, Peter-Derex L, Thomas J, et al
Oscillatory and nonoscillatory sleep electroencephalographic biomarkers of the epileptic network.
Epilepsia. 2024 Aug 24. doi: 10.1111/epi.18088.
PubMed Abstract available

KLIMES P, Nejedly P, Hrtonova V, Cimbalnik J, et al
Interictal stereo-electroencephalography features below 45 Hz are sufficient for correct localization of the epileptogenic zone and postsurgical outcome prediction.
Epilepsia. 2024 Aug 24. doi: 10.1111/epi.18081.
PubMed Abstract available

BIALER M, Johannessen SI, Koepp MJ, Perucca E, et al
Progress report on new medications for seizures and epilepsy: A summary of the 17th Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVII). II. Drugs in more advanced clinical development.
Epilepsia. 2024 Aug 22. doi: 10.1111/epi.18075.
PubMed Abstract available

SUN Y, Ku MY, Liu CC, Chien LN, et al
Characteristics of motor vehicle crashes and fatality risk among drivers with epilepsy.
Epilepsia. 2024 Aug 21. doi: 10.1111/epi.18097.
PubMed Abstract available

ERVIN B, Kargol C, Byars AW, Buroker J, et al
High-gamma modulation language mapping and cognitive outcomes after epilepsy surgery.
Epilepsia. 2024 Aug 20. doi: 10.1111/epi.18096.
PubMed Abstract available

AYOUB D, Jaafar F, Al-Hajje A, Salameh P, et al
Predictors of drug-resistant epilepsy in childhood epilepsy syndromes: A subgroup analysis from a prospective cohort study.
Epilepsia. 2024 Aug 16. doi: 10.1111/epi.18100.
PubMed Abstract available

WORRELL GA, Cui J, Mivalt F, Kremen V, et al
Letter regarding "Modification of brain conductivity in human focal epilepsy: A model-based estimation from stereoelectroencephalography" by Lagarde et al.
Epilepsia. 2024 Aug 14. doi: 10.1111/epi.18093.
PubMed

VON WREDE R, Witt JA, Jessen N, Lossius MI, et al
Screening for depression in patients with epilepsy: What are the benefits for physicians and patients in the real-life setting.
Epilepsia. 2024 Aug 14. doi: 10.1111/epi.18089.
PubMed Abstract available

CERULLI IRELLI E, Cocchi E, Gesche J, Pena-Ceballos J, et al
Lamotrigine vs levetiracetam in female patients of childbearing age with juvenile absence epilepsy: A Bayesian reanalysis.
Epilepsia. 2024 Aug 10. doi: 10.1111/epi.18087.
PubMed Abstract available

KLOOSTERMAN IEM, Haenen AI, Poortvliet-Koedam ELGE, Lazeron RHC, et al
Psychogenic non-epileptic (functional) seizures in adults with intellectual disability and epilepsy: A matched case-control study.
Epilepsia. 2024 Aug 9. doi: 10.1111/epi.18085.
PubMed Abstract available

SAHU JK, Madaan P, Wanigasinghe J, Chand P, et al
Mitigating treatment lag for infantile epileptic spasms syndrome in low- and middle-income countries: Key recommendations from the South Asia allied IESS Research Group.
Epilepsia. 2024 Aug 9. doi: 10.1111/epi.18090.
PubMed

ZHAO-FLEMING HH, Guo Y, Britton JW, Dubey D, et al
Outcomes of surgical resection and vagus nerve stimulation in patients with medically refractory epilepsy and glutamic acid decarboxylase 65 antibody positivity.
Epilepsia. 2024 Aug 7. doi: 10.1111/epi.18086.
PubMed Abstract available

DEZSI G, Ozturk E, Wong D, Hudson MR, et al
Fluoxetine accelerates epileptogenesis and magnifies disease severity in a rat model of acquired epilepsy.
Epilepsia. 2024 Aug 5. doi: 10.1111/epi.18080.
PubMed Abstract available

MEIJER WC, Gorter JA
Role of blood-brain barrier dysfunction in the development of poststroke epilepsy.
Epilepsia. 2024 Aug 5. doi: 10.1111/epi.18072.
PubMed Abstract available

WILSON W, Pittman DJ, Dykens P, Mosher V, et al
The hemodynamic response to co-occurring interictal epileptiform discharges and high-frequency oscillations localizes the seizure-onset zone.
Epilepsia. 2024 Aug 5. doi: 10.1111/epi.18071.
PubMed Abstract available

THOMAS J, Abdallah C, Cai Z, Jaber K, et al
Investigating current clinical opinions in stereoelectroencephalography-informed epilepsy surgery.
Epilepsia. 2024 Aug 3. doi: 10.1111/epi.18076.
PubMed Abstract available

ROGHANI A, Wang CP, Henion A, Amuan M, et al
Mortality among veterans with epilepsy: Temporal significance of traumatic brain injury exposure.
Epilepsia. 2024;65:2255-2269.
PubMed Abstract available

PEREZ-PEREZ D, Monio-Baca C, von Ruden EL, Buchecker V, et al
Preclinical efficacy profiles of the sigma-1 modulator E1R and of fenfluramine in two chronic mouse epilepsy models.
Epilepsia. 2024;65:2470-2482.
PubMed Abstract available

Correction to "patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA-Epilepsy study".
Epilepsia. 2024;65:2501.
PubMed

SPERLING MR
Farewell from the Editor-in-Chief.
Epilepsia. 2024;65:2183-2184.
PubMed

ABBOTT MJ, Knupp KG
SCN8A modified Delphi commentary.
Epilepsia. 2024;65:2339-2340.
PubMed

GIUSTOZZI M, Calvello C, Eusebi P, Paolini Paoletti F, et al
Safety and efficacy of concomitant treatment with non-vitamin K antagonist oral anticoagulants and antiseizure medications: A propensity score matching cohort study.
Epilepsia. 2024;65:e141-e147.
PubMed Abstract available

KERR WT, Ngo LY, Zhu L, Patten A, et al
Time to prerandomization seizure count design sufficiently assessed the safety and tolerability of perampanel for the treatment of primary generalized tonic-clonic seizures.
Epilepsia. 2024;65:2412-2422.
PubMed Abstract available

GEORGE AG, Beers CA, Wilson W, Mosher V, et al
Mesial temporal lobe spiking reveals distinct patterns of blood oxygen level-dependent functional magnetic resonance imaging activation using simultaneous intracranial electroencephalography-functional magnetic resonance imaging.
Epilepsia. 2024;65:2295-2307.
PubMed Abstract available

GHARBI O, Lamrani Y, St-Jean J, Jahani A, et al
Detection of focal to bilateral tonic-clonic seizures using a connected shirt.
Epilepsia. 2024;65:2280-2294.
PubMed Abstract available

July 2024

CROSS JH
Thank you to the outgoing editor-in-chief of Epilepsia, Michael Sperling: International League Against Epilepsy.
Epilepsia. 2024 Jul 31. doi: 10.1111/epi.18057.
PubMed

LIN YC, Lin CW, Meng LC, Huang ST, et al
Uses of antiseizure medication among pregnant women with epilepsy and risk of adverse obstetric outcomes: A group-based trajectory analysis.
Epilepsia. 2024 Jul 30. doi: 10.1111/epi.18064.
PubMed Abstract available

AAFTINK D, Reijneveld JC, de Lange F, Sander JW, et al
Grading objective diagnostic components in paroxysmal events: One-year follow-up at a tertiary epilepsy center.
Epilepsia. 2024 Jul 26. doi: 10.1111/epi.18062.
PubMed Abstract available

NANDA P, Sisterson N, Walton A, Chu CJ, et al
Centromedian region thalamic responsive neurostimulation mitigates idiopathic generalized and multifocal epilepsy with focal to bilateral tonic-clonic seizures.
Epilepsia. 2024 Jul 25. doi: 10.1111/epi.18070.
PubMed Abstract available

FOTEDAR N, Luders HO
Nocturnal paroxysmal dystonia to sleep-related hypermotor epilepsy: A critical review.
Epilepsia. 2024 Jul 24. doi: 10.1111/epi.18067.
PubMed Abstract available

DE MEULEMEESTER AS, Reid C, Auvin S, Carlen PL, et al
WONOEP appraisal: Modeling early onset epilepsies.
Epilepsia. 2024 Jul 23. doi: 10.1111/epi.18063.
PubMed Abstract available

BRAUN M, Riney K
Have epilepsy outcomes changed for children with tuberous sclerosis complex in Queensland, Australia?
Epilepsia. 2024 Jul 23. doi: 10.1111/epi.18069.
PubMed Abstract available

DOBSON H, Al Maawali S, Malpas C, Santillo AF, et al
Elevated plasma neurofilament light and glial fibrillary acidic protein in epilepsy versus nonepileptic seizures and nonepileptic disorders.
Epilepsia. 2024 Jul 20. doi: 10.1111/epi.18065.
PubMed Abstract available

BIALER M, Johannessen SI, Koepp MJ, Perucca E, et al
Progress report on new medications for seizures and epilepsy: A summary of the 17th Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVII). I. Drugs in preclinical and early clinical development.
Epilepsia. 2024 Jul 15. doi: 10.1111/epi.18056.
PubMed Abstract available

PURNELL BS, Petrucci AN, Li R, Buchanan GF, et al
Effect of adenosinergic manipulations on amygdala-kindled seizures in mice: Implications for sudden unexpected death in epilepsy.
Epilepsia. 2024 Jul 9. doi: 10.1111/epi.18059.
PubMed Abstract available

CHASSOUX F, Navarro V, Quirins M, Laurent A, et al
Vitamin D deficiency and effect of treatment on seizure frequency and quality of life parameters in patients with drug-resistant epilepsy: A randomized clinical trial.
Epilepsia. 2024 Jul 9. doi: 10.1111/epi.18050.
PubMed Abstract available

CUCCURULLO C, Cerulli Irelli E, Ugga L, Riva A, et al
Clinical features and genotype-phenotype correlations in epilepsy patients with de novo DYNC1H1 variants.
Epilepsia. 2024 Jul 2. doi: 10.1111/epi.18054.
PubMed Abstract available

KWON CS, Chua MMJ, Jette N, Rolston JD, et al
A knowledge synthesis of health research reporting standards relevant to epilepsy surgery.
Epilepsia. 2024 Jul 1. doi: 10.1111/epi.18047.
PubMed Abstract available

BLUETT-DUNCAN M, Bullen P, Campbell E, Clayton-Smith J, et al
The use of parent-completed questionnaires to investigate developmental outcomes in large populations of children exposed to antiseizure medications in pregnancy.
Epilepsia. 2024;65:2017-2029.
PubMed Abstract available

LAU LA, Zhao Z, Gomperts SN, Staley KJ, et al
Cellular resolution contributions to ictal population signals.
Epilepsia. 2024;65:2165-2178.
PubMed Abstract available

VAKILNA YS, Li X, Hampson JS, Huang Y, et al
Reliable detection of generalized convulsive seizures using an off-the-shelf digital watch: A multisite phase 2 study.
Epilepsia. 2024;65:2054-2068.
PubMed Abstract available

WU S, Issa NP, Rose SL, Haider HA, et al
Depth versus surface: A critical review of subdural and depth electrodes in intracranial electroencephalographic studies.
Epilepsia. 2024;65:1868-1878.
PubMed Abstract available

PINEAU L, Buhler E, Tarhini S, Bauer S, et al
Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C N-methyl-D-aspartate receptors.
Epilepsia. 2024;65:2111-2126.
PubMed Abstract available

EYAL AD, Eyal S
Increasing challenges to trial recruitment: Is it time to change the inclusion criteria for investigational compounds, not just for study participants?
Epilepsia. 2024;65:1907-1915.
PubMed

PANCHAVATI S, Daida A, Edmonds B, Miyakoshi M, et al
Uncovering spatiotemporal dynamics of the corticothalamic network at ictal onset.
Epilepsia. 2024;65:1989-2003.
PubMed Abstract available

June 2024

VESSELL M, Willett A, Ugiliweneza B, Sharma M, et al
National 22-year epilepsy surgery landscape shows increasing open and minimally invasive pediatric epilepsy surgery.
Epilepsia. 2024 Jun 29. doi: 10.1111/epi.18030.
PubMed Abstract available

DUBENKO A, Morelli R, Cross JH, Hall J, et al
Mental health and quality of life of individuals with epilepsy during the war in Ukraine.
Epilepsia. 2024 Jun 29. doi: 10.1111/epi.18052.
PubMed Abstract available

DOERRFUSS JI, Graf L, Husing T, Holtkamp M, et al
Risk of breakthrough seizures depends on type and etiology of epilepsy.
Epilepsia. 2024 Jun 29. doi: 10.1111/epi.18048.
PubMed Abstract available

CLAY JL, Mirza FA, Hulou KD, Raslau FD, et al
Value and potential pitfalls of morphometric analysis of magnetic resonance imaging in epilepsy.
Epilepsia. 2024 Jun 21. doi: 10.1111/epi.18049.
PubMed

GIL-NAGEL A, Cross JH, Devinsky O, Ceulemans B, et al
Comprehensive scoping review of fenfluramine's role in managing generalized tonic-clonic seizures in developmental and epileptic encephalopathies.
Epilepsia. 2024 Jun 21. doi: 10.1111/epi.18020.
PubMed Abstract available

HENDRIX E, Vande Vyver M, Holt M, Smolders I, et al
Regulatory T cells as a possible new target in epilepsy?
Epilepsia. 2024 Jun 18. doi: 10.1111/epi.18038.
PubMed Abstract available

SPERLING MR
An interview with Marwa Elamin, 2024 Epilepsia prize winner for basic science research.
Epilepsia. 2024 Jun 17. doi: 10.1111/epi.18041.
PubMed

SPERLING MR
An interview with Benjamin D. Wissel, 2024 Epilepsia Prize winner for clinical research.
Epilepsia. 2024 Jun 17. doi: 10.1111/epi.18042.
PubMed

CHIRIBOGA N, Spentzas T, Abu-Sawwa R
A systematic review and meta-analysis of ketamine in pediatric status epilepticus.
Epilepsia. 2024 Jun 17. doi: 10.1111/epi.18035.
PubMed Abstract available

SHAH U, Rajeshree S, Sahu A, Kalika M, et al
Cross-cultural application of the international classification of cognitive disorders in epilepsy cognitive phenotypes in people with temporal lobe epilepsy in India.
Epilepsia. 2024 Jun 15. doi: 10.1111/epi.18043.
PubMed Abstract available

BERTRAM EH, Dudek FE
Addressing the problems of treatment failure in epilepsy: You cannot fix what you do not understand.
Epilepsia. 2024 Jun 15. doi: 10.1111/epi.18044.
PubMed

AHN S, Edmonds B, Rajaraman RR, Rao LM, et al
Bilateral centromedian nucleus of thalamus responsive neurostimulation for pediatric-onset drug-resistant epilepsy.
Epilepsia. 2024 Jun 7. doi: 10.1111/epi.18031.
PubMed Abstract available

YOUNG E, Harris R, Lieffering N, de Valles-Ibanez G, et al
SCN8A self-limited infantile epilepsy: Does epilepsy resolve?
Epilepsia. 2024 Jun 7. doi: 10.1111/epi.18016.
PubMed Abstract available

HANIN A, Jimenez AD, Gopaul M, Asbell H, et al
Trends in management of patients with new-onset refractory status epilepticus (NORSE) from 2016 to 2023: An interim analysis.
Epilepsia. 2024 Jun 5. doi: 10.1111/epi.18014.
PubMed Abstract available

KAUFMANN E, Peltola J, Colon AJ, Lehtimaki K, et al
Long-term evaluation of anterior thalamic deep brain stimulation for epilepsy in the European MORE registry.
Epilepsia. 2024 Jun 5. doi: 10.1111/epi.18003.
PubMed Abstract available

LAM HW, Patodia S, Zeicu C, Lim YM, et al
Quantitative cellular pathology of the amygdala in temporal lobe epilepsy and correlation with magnetic resonance imaging volumetry, tissue microstructure, and sudden unexpected death in epilepsy risk factors.
Epilepsia. 2024 Jun 5. doi: 10.1111/epi.18033.
PubMed Abstract available

KOROUKIAN SM, Fein HL, Vu L, Bensken WP, et al
Excess prevalence of preexisting chronic conditions in older adults with incident epilepsy.
Epilepsia. 2024 Jun 4. doi: 10.1111/epi.18032.
PubMed Abstract available

WAGSTYL K, Kobow K, Casillas-Espinosa PM, Cole AJ, et al
WONOEP 2022: Neurotechnology for the diagnosis of epilepsy.
Epilepsia. 2024 Jun 3. doi: 10.1111/epi.18028.
PubMed Abstract available

IKEGAYA N, Aung T, Mallela A, Hect JL, et al
Thalamic stereoelectroencephalography for neuromodulation target selection: Proof of concept and review of literature of pulvinar direct electrical stimulation.
Epilepsia. 2024;65:e79-e86.
PubMed Abstract available

HAGEMANN A, Herting A, Klimpel D, Bien CG, et al
Ethosuximide lowers lamotrigine serum concentrations: Evidence for a clinically relevant interaction.
Epilepsia. 2024;65:e73-e78.
PubMed Abstract available

GOLDENHOLZ DM, Eccleston C, Moss R, Westover MB, et al
Prospective validation of a seizure diary forecasting falls short.
Epilepsia. 2024;65:1730-1736.
PubMed Abstract available

ZUBERI SM, Wirrell E, Tinuper P, Nabbout R, et al
Response: Do all individuals with Dravet syndrome have intellectual disability?
Epilepsia. 2024;65:1803-1804.
PubMed

GUO J, Min D, Farrell EK, Zhou Y, et al
Enhancing the action of serotonin by three different mechanisms prevents spontaneous seizure-induced mortality in Dravet mice.
Epilepsia. 2024;65:1791-1800.
PubMed Abstract available

KLEIN KM, Mascarenhas R, Merrikh D, Khanbabaei M, et al
Identification of a mosaic MTOR variant in purified neuronal DNA in a patient with focal cortical dysplasia using a novel depth electrode harvesting technique.
Epilepsia. 2024;65:1768-1776.
PubMed Abstract available

ABARRATEGUI B, Pelliccia V, Giovannelli G, Nichelatti M, et al
New stimulation procedures for language mapping in stereo-EEG.
Epilepsia. 2024;65:1720-1729.
PubMed Abstract available

JAVIDI SS, He X, Ankeeta A, Zhang Q, et al
Edge-wise analysis reveals white matter connectivity associated with focal to bilateral tonic-clonic seizures.
Epilepsia. 2024;65:1756-1767.
PubMed Abstract available

DING Z, Hu S, Su TY, Choi JY, et al
Combining magnetic resonance fingerprinting with voxel-based morphometric analysis to reduce false positives for focal cortical dysplasia detection.
Epilepsia. 2024;65:1631-1643.
PubMed Abstract available

REILLY C, Bjurulf B, Hallbook T
Do all individuals with Dravet syndrome have intellectual disability?
Epilepsia. 2024;65:1801-1802.
PubMed

May 2024

GE J, Xie S, Duan J, Tian B, et al
Imbalance between hippocampal projection cell and parvalbumin interneuron architecture increases epileptic susceptibility in mouse model of methyl CpG binding protein 2 duplication syndrome.
Epilepsia. 2024 May 31. doi: 10.1111/epi.18027.
PubMed Abstract available

GLATT S, Shohat S, Yam M, Goldstein L, et al
Cannabidiol-enriched oil for adult patients with drug-resistant epilepsy: Prospective clinical and electrophysiological study.
Epilepsia. 2024 May 29. doi: 10.1111/epi.18025.
PubMed Abstract available

LEINONEN MK, Igland J, Dreier JW, Alvestad S, et al
Socioeconomic differences in use of antiseizure medication in pregnancies with maternal epilepsy: A population-based study from Nordic universal health care systems.
Epilepsia. 2024 May 28. doi: 10.1111/epi.18022.
PubMed Abstract available

BHANDARE A, Haley M, Torrico Anderson V, Domingos LB, et al
ArcKR expression modifies synaptic plasticity following epileptic activity: Differential effects with in vitro and in vivo seizure-induction protocols.
Epilepsia. 2024 May 28. doi: 10.1111/epi.17981.
PubMed Abstract available

CONECKER G, Xia MY, Hecker J, Achkar C, et al
Global modified Delphi consensus on diagnosis, phenotypes, and treatment of SCN8A-related epilepsy and/or neurodevelopmental disorders.
Epilepsia. 2024 May 27. doi: 10.1111/epi.17992.
PubMed Abstract available

CONECKER G, Xia MY, Hecker J, Achkar C, et al
Global modified-Delphi consensus on comorbidities and prognosis of SCN8A-related epilepsy and/or neurodevelopmental disorders.
Epilepsia. 2024 May 27. doi: 10.1111/epi.17991.
PubMed Abstract available

BARBOUR K, Tian N, Yozawitz EG, Wolf S, et al
Population-based study of rare epilepsy incidence in a US urban population.
Epilepsia. 2024 May 25. doi: 10.1111/epi.18029.
PubMed Abstract available

TORRES N, de Montalivet E, Borntrager Q, Benahmed S, et al
Focal cooling: An alternative treatment for drug-resistant epilepsy in a mesial temporal lobe epilepsy primate model-A preliminary study.
Epilepsia. 2024 May 25. doi: 10.1111/epi.18012.
PubMed Abstract available

REECHER HM, Bearden DJ, Koop JI, Berl MM, et al
The changing landscape of electrical stimulation language mapping with subdural electrodes and stereoelectroencephalography for pediatric epilepsy: A literature review and commentary.
Epilepsia. 2024 May 24. doi: 10.1111/epi.18009.
PubMed Abstract available

TAIT L, Staniaszek LE, Galizia E, Martin-Lopez D, et al
Estimating the likelihood of epilepsy from clinically noncontributory electroencephalograms using computational analysis: A retrospective, multisite case-control study.
Epilepsia. 2024 May 23. doi: 10.1111/epi.18024.
PubMed Abstract available

KLOC ML, Holmes GL, Barry JM
Sex differences in cholinergic signaling affect functional outcomes for theta-gamma coordination in hippocampal subcircuits following experimental febrile status epilepticus.
Epilepsia. 2024 May 23. doi: 10.1111/epi.18017.
PubMed Abstract available

GOLDENHOLZ D, Brinkmann BH, Westover MB
How accurate do self-reported seizures need to be for effective medication management in epilepsy?
Epilepsia. 2024 May 22. doi: 10.1111/epi.18019.
PubMed Abstract available

ANTAYA TC, Espino-Alvarado PH, Oiamo T, Wilk P, et al
Association of outdoor air and noise pollution with unprovoked seizures and new onset epilepsy: A systematic review and meta-analysis.
Epilepsia. 2024 May 22. doi: 10.1111/epi.18010.
PubMed Abstract available

GUO D, Han L, Godale CM, Rensing NR, et al
A role of dentate gyrus mechanistic target of rapamycin activation in epileptogenesis in a mouse model of posttraumatic epilepsy.
Epilepsia. 2024 May 18. doi: 10.1111/epi.18011.
PubMed Abstract available

MITCHELL JW, Sossi F, Miller I, Jaber PB, et al
Development of an International Standard Set of Outcomes and Measurement Methods for Routine Practice for Infants, Children, and Adolescents with Epilepsy: The International Consortium for Health Outcomes Measurement Consensus Recommendations.
Epilepsia. 2024 May 17. doi: 10.1111/epi.17976.
PubMed Abstract available

PADMASOLA GP, Friscourt F, Rigoni I, Vulliemoz S, et al
Involvement of the contralateral hippocampus in ictal-like but not interictal epileptic activities in the kainate mouse model of temporal lobe epilepsy.
Epilepsia. 2024 May 17. doi: 10.1111/epi.17970.
PubMed Abstract available

NGADIMON IW, Mohan D, Shaikh MF, Khoo CS, et al
Incidence and predictors of posttraumatic epilepsy and cognitive impairment in patients with traumatic brain injury: A retrospective cohort study in Malaysia.
Epilepsia. 2024 May 16. doi: 10.1111/epi.18007.
PubMed Abstract available

GIOVANNINI G, Giannoccaro MP, Cioclu MC, Orlandi N, et al
FADD gene pathogenic variants causing recurrent febrile infection-related epilepsy syndrome: Case report and literature review.
Epilepsia. 2024 May 16. doi: 10.1111/epi.18008.
PubMed Abstract available

KREINTER H, Espino PH, Mejia S, Alorabi K, et al
Disrupting the epileptogenic network with stereoelectroencephalography-guided radiofrequency thermocoagulation.
Epilepsia. 2024 May 13. doi: 10.1111/epi.18005.
PubMed Abstract available

KOUCHI H, Smith J, Georges B, Cracknell F, et al
Serotonin 2C receptor in a rat model of temporal lobe epilepsy: From brainstem expression to pharmacological blockade in relation to ventilatory function.
Epilepsia. 2024 May 13. doi: 10.1111/epi.18006.
PubMed Abstract available

MITCHELL JW, Sossi F, Miller I, Jaber PB, et al
Development of an International Standard Set of Outcomes and Measurement Methods for Routine Practice for Adults with Epilepsy: The International Consortium for Health Outcomes Measurement Consensus Recommendations.
Epilepsia. 2024 May 13. doi: 10.1111/epi.17971.
PubMed Abstract available

ELLIS CA, Tu D, Oliver KL, Mefford HC, et al
Familial aggregation of seizure outcomes in four familial epilepsy cohorts.
Epilepsia. 2024 May 13. doi: 10.1111/epi.18004.
PubMed Abstract available

HANNON T, Fernandes KM, Wong V, Nurse ES, et al
Over- and underreporting of seizures: How big is the problem?
Epilepsia. 2024;65:1406-1414.
PubMed Abstract available

SUZUKI T, Natsume J, Ito Y, Ito T, et al
Effect of levodopa on pathological gait in Dravet syndrome: A randomized crossover trial using three-dimensional gait analysis.
Epilepsia. 2024;65:1304-1313.
PubMed Abstract available

CROSS JH, Benitez A, Roth J, Andrews JS, et al
A comprehensive systematic literature review of the burden of illness of Lennox-Gastaut syndrome on patients, caregivers, and society.
Epilepsia. 2024;65:1224-1239.
PubMed Abstract available

MAYER J, Mbizvo GK, Bucci T, Marson A, et al
Association of antiseizure medications and adverse cardiovascular events: A global health federated network analysis.
Epilepsia. 2024;65:1264-1274.
PubMed Abstract available

PERUCCA P, Bourikas D, Voinescu PE, Vadlamudi L, et al
Lacosamide and pregnancy: Data from spontaneous and solicited reports.
Epilepsia. 2024;65:1275-1284.
PubMed Abstract available

FALLIK N, Trakhtenbroit I, Fahoum F, Goldstein L, et al
Therapeutic drug monitoring in pregnancy: Levetiracetam.
Epilepsia. 2024;65:1285-1293.
PubMed Abstract available

SULLIVAN J, Benitez A, Roth J, Andrews JS, et al
A systematic literature review on the global epidemiology of Dravet syndrome and Lennox-Gastaut syndrome: Prevalence, incidence, diagnosis, and mortality.
Epilepsia. 2024;65:1240-1263.
PubMed Abstract available

April 2024

YAZARLOU F, Lipovich L, Loeb JA
Emerging roles of long non-coding RNAs in human epilepsy.
Epilepsia. 2024 Apr 30. doi: 10.1111/epi.17937.
PubMed Abstract available

RATCLIFFE C, Pradeep V, Marson A, Keller SS, et al
Clinical prediction models for treatment outcomes in newly diagnosed epilepsy: A systematic review.
Epilepsia. 2024 Apr 30. doi: 10.1111/epi.17994.
PubMed Abstract available

WANG SH, Arnulfo G, Nobili L, Myrov V, et al
Neuronal synchrony and critical bistability: Mechanistic biomarkers for localizing the epileptogenic network.
Epilepsia. 2024 Apr 30. doi: 10.1111/epi.17996.
PubMed Abstract available

TANTILLO GB, Dongarwar D, Venkatasubba Rao CP, Johnson A, et al
Health care disparities in morbidity and mortality in adults with acute and remote status epilepticus: A national study.
Epilepsia. 2024 Apr 30. doi: 10.1111/epi.17965.
PubMed Abstract available

DI GIACOMO R, Burini A, Chiarello D, Pelliccia V, et al
Ictal fast activity chirps as markers of the epileptogenic zone.
Epilepsia. 2024 Apr 30. doi: 10.1111/epi.17995.
PubMed Abstract available

FONG MWK, Stephens E, Brockington A, Jayabal J, et al
Status epilepticus in Auckland, New Zealand: Treatment patterns and determinants of outcome in a prospective population-based cohort.
Epilepsia. 2024 Apr 18. doi: 10.1111/epi.17975.
PubMed Abstract available

JIMENEZ AD, Gopaul M, Asbell H, Aydemir S, et al
Comparative analysis of patients with new onset refractory status epilepticus preceded by fever (febrile infection-related epilepsy syndrome) versus without prior fever: An interim analysis.
Epilepsia. 2024 Apr 16. doi: 10.1111/epi.17988.
PubMed Abstract available

SPECHT U, Lahr D, May TW, Speicher P, et al
Rehabilitation in patients with newly diagnosed epilepsy: A controlled, 1-year follow-up study on a specialized inpatient rehabilitation program.
Epilepsia. 2024 Apr 16. doi: 10.1111/epi.17985.
PubMed Abstract available

LEWIS DV, Voyvodic J, Shinnar S, Chan S, et al
Hippocampal sclerosis and temporal lobe epilepsy following febrile status epilepticus: The FEBSTAT study.
Epilepsia. 2024 Apr 12. doi: 10.1111/epi.17979.
PubMed Abstract available

VIGNATELLI L, Tontini V, Meletti S, Camerlingo M, et al
Clinical practice guidelines on the management of status epilepticus in adults: A systematic review.
Epilepsia. 2024 Apr 12. doi: 10.1111/epi.17982.
PubMed Abstract available

VARY O'NEAL A, Tamani I, Mendo CW, Josephson CB, et al
Epilepsy surgery in adults older than 50 years: A systematic review and meta-analysis.
Epilepsia. 2024 Apr 6. doi: 10.1111/epi.17972.
PubMed Abstract available

MASON JA, Juarez-Colunga E, Knupp KG
Electrographic screening for infantile epileptic spasms syndrome in a single sleep-wake cycle.
Epilepsia. 2024 Apr 4. doi: 10.1111/epi.17967.
PubMed Abstract available

Correction to "Efficacy of cannabidiol in convulsive and nonconvulsive seizure types associated with treatment-resistant epilepsies in the Expanded Access Program".
Epilepsia. 2024 Apr 4. doi: 10.1111/epi.17977.
PubMed

LI S, Yi J, Tuo Y, Nie G, et al
Population pharmacokinetics and dosing optimization of perampanel in children with epilepsy: A real-world study.
Epilepsia. 2024 Apr 4. doi: 10.1111/epi.17954.
PubMed Abstract available

TANTILLO GB, Sullivan-Baca E, Rehman R, Lopez MR, et al
Health care utilization of Hispanic/Latino veterans with epilepsy: A national population-based study.
Epilepsia. 2024 Apr 1. doi: 10.1111/epi.17948.
PubMed Abstract available

FOUNTAIN NB, Quigg M, Murchison CF, Carrazana E, et al
Analysis of seizure-cluster circadian periodicity from a long-term, open-label safety study of diazepam nasal spray.
Epilepsia. 2024;65:920-928.
PubMed Abstract available

GOLDENHOLZ DM, Karoly PJ, Viana PF, Nurse E, et al
Minimum clinical utility standards for wearable seizure detectors: A simulation study.
Epilepsia. 2024;65:1017-1028.
PubMed Abstract available

TSALOUCHIDOU PE, Hoffmann J, Strehlau S, Linka L, et al
Morphometric magnetic resonance imaging (MRI) postprocessing in MRI-negative patients with first unprovoked seizure.
Epilepsia. 2024;65:1107-1114.
PubMed Abstract available

March 2024

VEGRIM HM, Dreier JW, Igland J, Gilhus NE, et al
Prescribing patterns for higher dose folic acid in pregnant women with epilepsy treated with antiseizure medication.
Epilepsia. 2024 Mar 30. doi: 10.1111/epi.17969.
PubMed Abstract available

SHAKHATREH L, Sinclair B, McLean C, Lui E, et al
Amygdala enlargement in temporal lobe epilepsy: Histopathology and surgical outcomes.
Epilepsia. 2024 Mar 28. doi: 10.1111/epi.17968.
PubMed Abstract available

CERULLI IRELLI E, Borioni MS, Morano A, Mazzeo A, et al
Frailty as a comprehensive health measure beyond seizure control in patients with epilepsy: A cross-sectional study.
Epilepsia. 2024 Mar 27. doi: 10.1111/epi.17964.
PubMed Abstract available

Correction to "Home recording of 3-Hz spike-wave discharges in adults with absence epilepsy using the wearable Sensor Dot".
Epilepsia. 2024 Mar 23. doi: 10.1111/epi.17973.
PubMed

CHARLEBOIS CM, Anderson DN, Smith EH, Davis TS, et al
Circadian changes in aperiodic activity are correlated with seizure reduction in patients with mesial temporal lobe epilepsy treated with responsive neurostimulation.
Epilepsia. 2024 Mar 22. doi: 10.1111/epi.17938.
PubMed Abstract available

BOSQUE VARELA P, Tabaee Damavandi P, Machegger L, Pruwasser T, et al
Magnetic resonance imaging fingerprints of status epilepticus: A case-control study.
Epilepsia. 2024 Mar 20. doi: 10.1111/epi.17949.
PubMed Abstract available

MAGRO G, Laterza V
Status epilepticus: Is there a Stage 1 plus?
Epilepsia. 2024 Mar 20. doi: 10.1111/epi.17953.
PubMed Abstract available

VERLY G, Oliveira LB, Delfino T, Batista S, et al
Assessing short-term and long-term security and efficacy of anterior nucleus of the thalamus deep brain stimulation for treating drug-resistant epilepsy: A systematic review and single-arm meta-analysis.
Epilepsia. 2024 Mar 20. doi: 10.1111/epi.17955.
PubMed Abstract available

ALCALA-ZERMENO JL, Fureman B, Grzeskowiak CL, Potnis O, et al
Racial disparities in the utilization of invasive neuromodulation devices for the treatment of drug-resistant focal epilepsy.
Epilepsia. 2024 Mar 20. doi: 10.1111/epi.17961.
PubMed Abstract available

Correction to "Long-term efficacy and safety of cannabidiol in patients with treatment-resistant epilepsies: Four-year results from the expanded access program".
Epilepsia. 2024 Mar 19. doi: 10.1111/epi.17959.
PubMed

COSTELLO DJ, Matthews E, Aurangzeb S, Doran E, et al
Clinical outcomes among initial survivors of cryptogenic new-onset refractory status epilepsy (NORSE).
Epilepsia. 2024 Mar 18. doi: 10.1111/epi.17950.
PubMed Abstract available

CETICA V, Pisano T, Lesca G, Marafi D, et al
Clinical and molecular characterization of patients with YWHAG-related epilepsy.
Epilepsia. 2024 Mar 16. doi: 10.1111/epi.17939.
PubMed Abstract available

CARTON RJ, Doyle MG, Kearney H, Steward CA, et al
Somatic variants as a cause of drug-resistant epilepsy including mesial temporal lobe epilepsy with hippocampal sclerosis.
Epilepsia. 2024 Mar 16. doi: 10.1111/epi.17943.
PubMed Abstract available

LAGARDE S, Modolo J, Yochum M, Carvallo A, et al
Modification of brain conductivity in human focal epilepsy: A model-based estimation from stereoelectroencephalography.
Epilepsia. 2024 Mar 16. doi: 10.1111/epi.17957.
PubMed Abstract available

MACDONALD-LAURS E, Warren AEL, Leventer RJ, Harvey AS, et al
Why did my seizures start now? Influences of lesion connectivity and genetic etiology on age at seizure onset in focal epilepsy.
Epilepsia. 2024 Mar 15. doi: 10.1111/epi.17947.
PubMed Abstract available

TOJIMA M, Shimotake A, Neshige S, Okada T, et al
Specific consistency score for rational selection of epilepsy resection surgery candidates.
Epilepsia. 2024 Mar 12. doi: 10.1111/epi.17945.
PubMed Abstract available

WILTROUT K, Brimble E, Poduri A
Comprehensive phenotypes of patients with SYNGAP1-related disorder reveals high rates of epilepsy and autism.
Epilepsia. 2024 Mar 12. doi: 10.1111/epi.17913.
PubMed Abstract available

LAPA S, Schwingshackl A, Frank U, Rosenow F, et al
Transient postictal dysphagia in older adults with focal structural epilepsy.
Epilepsia. 2024 Mar 8. doi: 10.1111/epi.17914.
PubMed Abstract available

CAMPBELL JM, Yost S, Gautam D, Herich A, et al
Delays in the diagnosis and surgical treatment of drug-resistant epilepsy: A cohort study.
Epilepsia. 2024 Mar 8. doi: 10.1111/epi.17944.
PubMed Abstract available

STRAFFORD H, Hollinghurst J, Lacey AS, Akbari A, et al
Epilepsy and the risk of COVID-19-related hospitalization and death: A population study.
Epilepsia. 2024 Mar 5. doi: 10.1111/epi.17910.
PubMed Abstract available

STRAFFORD H, Hollinghurst J, Lacey AS, Akbari A, et al
Health care utilization and mortality for people with epilepsy during COVID-19: A population study.
Epilepsia. 2024 Mar 5. doi: 10.1111/epi.17920.
PubMed Abstract available

REITER JT, Schulte F, Bauer T, David B, et al
Evidence for interictal blood-brain barrier dysfunction in people with epilepsy.
Epilepsia. 2024 Mar 4. doi: 10.1111/epi.17929.
PubMed Abstract available

HANIN A, Muscal E, Hirsch LJ
Second-line immunotherapy in new onset refractory status epilepticus.
Epilepsia. 2024 Mar 2. doi: 10.1111/epi.17933.
PubMed Abstract available

VLACHOU M, Ryvlin P, Armand Larsen S, Beniczky S, et al
Focal electroclinical features in generalized tonic-clonic seizures: Decision flowchart for a diagnostic challenge.
Epilepsia. 2024;65:725-738.
PubMed Abstract available

PERUCCA E, French JA, Aljandeel G, Balestrini S, et al
Which terms should be used to describe medications used in the treatment of seizure disorders? An ILAE position paper.
Epilepsia. 2024;65:533-541.
PubMed Abstract available

ILYAS A, Vilella L, Restrepo CE, Johnson J, et al
The value of additional electrodes when stereo-electroencephalography is inconclusive.
Epilepsia. 2024;65:641-650.
PubMed Abstract available

LUCAS A, Scheid BH, Pattnaik AR, Gallagher R, et al
iEEG-recon: A fast and scalable pipeline for accurate reconstruction of intracranial electrodes and implantable devices.
Epilepsia. 2024;65:817-829.
PubMed Abstract available

MARTINEZ S, Bonnin SS, Radosevich J, Haller JT, et al
Rapid administration of undiluted loading doses of levetiracetam.
Epilepsia. 2024;65:615-619.
PubMed Abstract available

February 2024

HANIN A, Eschbach K, Gofton TE, Gopaul M, et al
New onset refractory status epilepticus: Summary of the NORSE Institute roundtable during the 2023 American Epilepsy Society meeting, Orlando, Florida.
Epilepsia. 2024 Feb 29. doi: 10.1111/epi.17934.
PubMed

RYVLIN P, Barba C, Bartolomei F, Baumgartner C, et al
Grading system for assessing the confidence in the epileptogenic zone reported in published studies: A Delphi consensus study.
Epilepsia. 2024 Feb 29. doi: 10.1111/epi.17928.
PubMed Abstract available

KILGORE-GOMEZ A, Norato G, Theodore WH, Inati SK, et al
Sleep physiology in patients with epilepsy: Influence of seizures on rapid eye movement (REM) latency and REM duration.
Epilepsia. 2024 Feb 27. doi: 10.1111/epi.17904.
PubMed Abstract available

KORINTHENBERG R, Bast T, Haberlandt E, Stephani U, et al
Efficacy and safety of corticosteroids and ACTH in epileptic syndromes beyond Infantile Epileptic Spasms Syndrome (IESS): A systematic review and meta-analysis.
Epilepsia. 2024 Feb 27. doi: 10.1111/epi.17918.
PubMed Abstract available

KERESTES R, Perry A, Vivash L, O'Brien TJ, et al
Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA-Epilepsy study.
Epilepsia. 2024 Feb 27. doi: 10.1111/epi.17881.
PubMed Abstract available

GALLAGHER D, Perez-Palma E, Bruenger T, Ghanty I, et al
Genotype-phenotype associations in 1018 individuals with SCN1A-related epilepsies.
Epilepsia. 2024 Feb 27. doi: 10.1111/epi.17882.
PubMed Abstract available

TERMAN SW, Guterman EL, Lin CC, Thompson MP, et al
Hospital variation of outcomes in status epilepticus.
Epilepsia. 2024 Feb 26. doi: 10.1111/epi.17927.
PubMed Abstract available

DREXLER R, Ricklefs FL, Ben-Haim S, Rada A, et al
Defining benchmark outcomes for mesial temporal lobe epilepsy surgery: A global multicenter analysis of 1119 cases.
Epilepsia. 2024 Feb 24. doi: 10.1111/epi.17923.
PubMed Abstract available

ZHOU C, Xie F, Wang D, Huang X, et al
Preoperative structural-functional coupling at the default mode network predicts surgical outcomes of temporal lobe epilepsy.
Epilepsia. 2024 Feb 23. doi: 10.1111/epi.17921.
PubMed Abstract available

HEBEL JM, Lanz M, Malina T, Stodieck SRG, et al
Effects of midazolam on high-frequency oscillations in amygdala and hippocampus of epilepsy patients.
Epilepsia. 2024 Feb 17. doi: 10.1111/epi.17916.
PubMed Abstract available

PUNIA V, Daruvala S, Dhakar MB, Zafar SF, et al
Immediate and long-term management practices of acute symptomatic seizures and epileptiform abnormalities: A cross-sectional international survey.
Epilepsia. 2024 Feb 15. doi: 10.1111/epi.17915.
PubMed Abstract available

AUVIN S, Guillo S, de Rycke Y, Tran D, et al
Benzodiazepines for pediatric epilepsies and their risks in a cohort within the French health care data.
Epilepsia. 2024 Feb 14. doi: 10.1111/epi.17906.
PubMed Abstract available

ZANELLO M, Garnier E, Carron R, Jegou A, et al
Stereo-EEG-based ictal functional connectivity in patients with periventricular nodular heterotopia-related epilepsy.
Epilepsia. 2024 Feb 12. doi: 10.1111/epi.17891.
PubMed Abstract available

TERMAN SW, Kirkpatrick L, Akiyama LF, Baajour W, et al
Current state of the epilepsy drug and device pipeline.
Epilepsia. 2024 Feb 12. doi: 10.1111/epi.17884.
PubMed Abstract available

LUCAS A, Mouchtaris S, Tranquille A, Sinha N, et al
Mapping hippocampal and thalamic atrophy in epilepsy: A 7-T magnetic resonance imaging study.
Epilepsia. 2024 Feb 12. doi: 10.1111/epi.17908.
PubMed Abstract available

LATTANZI S, Orlandi N, Giovannini G, Brigo F, et al
The risk of unprovoked seizure occurrence after status epilepticus in adults.
Epilepsia. 2024 Feb 10. doi: 10.1111/epi.17912.
PubMed Abstract available

HANIN A, Chollet C, Demeret S, Di Meglio L, et al
Metabolomic changes in adults with status epilepticus: A human case-control study.
Epilepsia. 2024 Feb 10. doi: 10.1111/epi.17899.
PubMed Abstract available

NTOLKERAS G, Makaram N, Bernabei M, De La Vega AC, et al
Interictal EEG source connectivity to localize the epileptogenic zone in patients with drug-resistant epilepsy: A machine learning approach.
Epilepsia. 2024 Feb 6. doi: 10.1111/epi.17898.
PubMed Abstract available

HADJINICOLAOU A, Briscoe Abath C, Singh A, Donatelli S, et al
Timing the clinical onset of epileptic spasms in infantile epileptic spasms syndrome: A tertiary health center's experience.
Epilepsia. 2024 Feb 5. doi: 10.1111/epi.17900.
PubMed Abstract available

KARABACAK M, Jagtiani P, Jain A, Panov F, et al
Tracing topics and trends in drug-resistant epilepsy research using a natural language processing-based topic modeling approach.
Epilepsia. 2024 Feb 5. doi: 10.1111/epi.17890.
PubMed Abstract available

SILVA ALVES A, Rigoni I, Megevand P, Lagarde S, et al
High-density electroencephalographic functional networks in genetic generalized epilepsy: Preserved whole-brain topology hides local reorganization.
Epilepsia. 2024 Feb 2. doi: 10.1111/epi.17903.
PubMed Abstract available

VAN DIESSEN E, van Amerongen RA, Zijlmans M, Otte WM, et al
Potential merits and flaws of large language models in epilepsy care: A critical review.
Epilepsia. 2024 Feb 2. doi: 10.1111/epi.17907.
PubMed Abstract available

FU Y, Zhang J, Cao Y, Ye L, et al
Recognition memory deficits detected through eye-tracking in well-controlled children with self-limited epilepsy with centrotemporal spikes.
Epilepsia. 2024 Feb 1. doi: 10.1111/epi.17902.
PubMed Abstract available

LO BARCO T, Garcelon N, Neuraz A, Nabbout R, et al
Natural history of rare diseases using natural language processing of narrative unstructured electronic health records: The example of Dravet syndrome.
Epilepsia. 2024;65:350-361.
PubMed Abstract available

PIETRAFUSA N, Trivisano M, Casellato S, Correale C, et al
Fenfluramine below the age of 2 years in Dravet syndrome: What about safety and efficacy?
Epilepsia. 2024;65:e7-e13.
PubMed Abstract available

ROBERTI R, Di Gennaro G, Anzellotti F, Arnaldi D, et al
A real-world comparison among third-generation antiseizure medications: Results from the COMPARE study.
Epilepsia. 2024;65:456-472.
PubMed Abstract available

PERRY MS, Scheffer IE, Sullivan J, Brunklaus A, et al
Severe communication delays are independent of seizure burden and persist despite contemporary treatments in SCN1A+ Dravet syndrome: Insights from the ENVISION natural history study.
Epilepsia. 2024;65:322-337.
PubMed Abstract available

LOSCHER W
On hidden factors and design-associated errors that may lead to data misinterpretation: An example from preclinical research on the potential seasonality of neonatal seizures.
Epilepsia. 2024;65:287-292.
PubMed Abstract available

January 2024

CERULLI IRELLI E, Cocchi E, Mostacci B, Orlando B, et al
Topiramate ban in women of childbearing potential with idiopathic generalized epilepsy: Does effectiveness offset the teratogenic risks?
Epilepsia. 2024 Jan 31. doi: 10.1111/epi.17892.
PubMed Abstract available

KUCIKIENE D, Rajkumar R, Timpte K, Heckelmann J, et al
EEG microstates show different features in focal epilepsy and psychogenic nonepileptic seizures.
Epilepsia. 2024 Jan 30. doi: 10.1111/epi.17897.
PubMed Abstract available

MOJZISOVA H, Elisak M, Krysl D, Hanzalova J, et al
Low prevalence of neural autoantibodies in perioperative cerebrospinal fluid samples of epilepsy surgery patients: A multicenter prospective study.
Epilepsia. 2024 Jan 27. doi: 10.1111/epi.17894.
PubMed Abstract available

THALWITZER KM, Xian J, de Campo D, Parthasarathy S, et al
Early life seizures and epileptic spasms in STXBP1-related disorders.
Epilepsia. 2024 Jan 27. doi: 10.1111/epi.17886.
PubMed Abstract available

BALDINI S, Duma GM, Danieli A, Antoniazzi L, et al
Electroencephalographic microstates as a potential neurophysiological marker differentiating bilateral from unilateral temporal lobe epilepsy.
Epilepsia. 2024 Jan 24. doi: 10.1111/epi.17893.
PubMed Abstract available

SHARMA A, Parfyonov M, Tiefenbach J, Hogue O, et al
Predictors of therapeutic response following thalamic neuromodulation for drug-resistant pediatric epilepsy: A systematic review and individual patient data meta-analysis.
Epilepsia. 2024 Jan 24. doi: 10.1111/epi.17883.
PubMed Abstract available

ANTAL DC, Altenmuller DM, Dumpelmann M, Scheiwe C, et al
Semiautomated electric source imaging determines epileptogenicity of encephaloceles in temporal lobe epilepsy.
Epilepsia. 2024 Jan 23. doi: 10.1111/epi.17879.
PubMed Abstract available

GOL M, Costa AM, Biagini G, Lucchi C, et al
Seizure progression is slowed by enhancing neurosteroid availability in the brain of epileptic rats.
Epilepsia. 2024 Jan 20. doi: 10.1111/epi.17887.
PubMed Abstract available

JANSON A, Sainburg L, Akbarian B, Johnson GW, et al
Indirect structural changes and reduced controllability after temporal lobe epilepsy resection.
Epilepsia. 2024 Jan 19. doi: 10.1111/epi.17889.
PubMed Abstract available

YOGANATHAN S, Whitney R, Thomas M, Danda S, et al
KCTD7-related progressive myoclonic epilepsy: Report of 42 cases and review of literature.
Epilepsia. 2024 Jan 17. doi: 10.1111/epi.17880.
PubMed Abstract available

OLSON HE, Amin S, Bahi-Buisson N, Devinsky O, et al
Long-term treatment with ganaxolone for seizures associated with cyclin-dependent kinase-like 5 deficiency disorder: Two-year open-label extension follow-up.
Epilepsia. 2024;65:37-45.
PubMed Abstract available

BLENKINSOP S, Wardrope A, Willis J, Sisodiya SM, et al
Climate change: Attitudes and concerns of, and learnings from, people with neurological conditions, carers, and health care professionals.
Epilepsia. 2024;65:95-106.
PubMed Abstract available

SHIN JH, Song MJ, Kim JH
Valproate use associated with frontal and cerebellar gray matter volume reductions: A voxel-based morphometry study.
Epilepsia. 2024;65:e1-e6.
PubMed Abstract available

SMITH J, Richerson G, Kouchi H, Duprat F, et al
Are we there yet? A critical evaluation of sudden and unexpected death in epilepsy models.
Epilepsia. 2024;65:9-25.
PubMed Abstract available

HOELTZENBEIN M, Bartz I, Fietz AK, Lohse L, et al
Antiepileptic treatment with levetiracetam during the first trimester and pregnancy outcome: An observational study.
Epilepsia. 2024;65:26-36.
PubMed Abstract available

MALTSEVA M, Rosenow F, Schubert-Bast S, Flege S, et al
Critical incidents, nocturnal supervision, and caregiver knowledge on SUDEP in patients with Dravet syndrome: A prospective multicenter study in Germany.
Epilepsia. 2024;65:115-126.
PubMed Abstract available

SHEN W, Flamm C, Delahanty AJ, Casteel E, et al
4-Phenylbutyrate promoted wild-type gamma-aminobutyric acid type A receptor trafficking, reduced endoplasmic reticulum stress, and mitigated seizures in Gabrg2(+/Q390X) mice associated with Dravet syndrome.
Epilepsia. 2024;65:204-217.
PubMed Abstract available

TSUR A, Spierer R, Cohen R, Blatch D, et al
First unprovoked seizures among soldiers recruited to the Israeli Defense Forces during 10 consecutive years: A population-based study.
Epilepsia. 2024;65:127-137.
PubMed Abstract available

WEIL AG, Dimentberg E, Lewis E, Ibrahim GM, et al
Development of an online calculator for the prediction of seizure freedom following pediatric hemispherectomy using the Hemispherectomy Outcome Prediction Scale (HOPS).
Epilepsia. 2024;65:46-56.
PubMed Abstract available

December 2023

HENTSCHEL M, Stoffel-Wagner B, Surges R, von Wrede R, et al
The value of drug level concentrations of brivaracetam, lacosamide and perampanel in the care of people with epilepsy.
Epilepsia. 2023 Dec 29. doi: 10.1111/epi.17873.
PubMed Abstract available

TERMAN SW, Kirkpatrick L, Kerr WT, Akiyama LF, et al
Challenges and directions in epilepsy diagnostics and therapeutics: proceedings of the 17(th) Epilepsy Therapies and Diagnostics Development conference.
Epilepsia. 2023 Dec 22. doi: 10.1111/epi.17875.
PubMed Abstract available

KASSABIAN B, Levy AM, Gardella E, Aledo-Serrano A, et al
Developmental epileptic encephalopathy in DLG4-related synaptopathy.
Epilepsia. 2023 Dec 22. doi: 10.1111/epi.17876.
PubMed Abstract available

NOVITSKAYA Y, Schutz E, Metternich B, Schulze-Bonhage A, et al
Add-on treatment with cenobamate is already effective at low doses in refractory focal epilepsy: a prospective observational study.
Epilepsia. 2023 Dec 22. doi: 10.1111/epi.17874.
PubMed Abstract available

LATTANZI S, Meletti S
Refractory status epilepticus: is there room for grading refractoriness?
Epilepsia. 2023 Dec 21. doi: 10.1111/epi.17836.
PubMed

ALJISHI A, Sherman BE, Huberdeau DM, Obaid S, et al
Statistical learning in epilepsy: behavioral and anatomical mechanisms in the human brain.
Epilepsia. 2023 Dec 20. doi: 10.1111/epi.17871.
PubMed Abstract available

TSYTSAREV V, Sopova JV, Leonova EI, Inyushin M, et al
Neurophotonics' methods in approach to in vivo animal epileptic models: advantages and limitations.
Epilepsia. 2023 Dec 20. doi: 10.1111/epi.17870.
PubMed Abstract available

AUVIN S, Arzimanoglou A, Brambilla I, French J, et al
Call for the use of the ILAE terminology for seizures and epilepsies by healthcare professionals and regulatory agencies to benefit patients and caregivers.
Epilepsia. 2023 Dec 17. doi: 10.1111/epi.17868.
PubMed

MICHAELIS R, Scholler H, Popkirov S, Edelhauser F, et al
Psychological Precursors of Epileptic Seizures.
Epilepsia. 2023 Dec 15. doi: 10.1111/epi.17865.
PubMed Abstract available

The role of copy number variants in the genetic architecture of common familial epilepsies.
Epilepsia. 2023 Dec 15. doi: 10.1111/epi.17860.
PubMed Abstract available

ASCHNER A, Kowal C, Arski O, Crispo JAG, et al
Prevalence of epileptiform electroencephalographic abnormalities in people without a history of seizures: A systematic review and meta-analysis.
Epilepsia. 2023 Dec 15. doi: 10.1111/epi.17864.
PubMed Abstract available

DECKER BM, Munger Clary H, Holmes MG, Al-Faraj AO, et al
Letter regarding "Seizure control in women with epilepsy undergoing assisted reproductive technology".
Epilepsia. 2023 Dec 14. doi: 10.1111/epi.17862.
PubMed

CASELLA C, Vecchiato K, Cromb D, Guo Y, et al
Widespread, depth-dependent cortical microstructure alterations in paediatric focal epilepsy.
Epilepsia. 2023 Dec 13. doi: 10.1111/epi.17861.
PubMed Abstract available

COPPOLA A, Krithika S, Iacomino M, Bobbili D, et al
Dissecting the genetics of spectrum of Epilepsies with Eyelid Myoclonia by exome sequencing.
Epilepsia. 2023 Dec 13. doi: 10.1111/epi.17859.
PubMed Abstract available

MULA M, Borghs S, Ferro B, Zaccara G, et al
Effect of drug treatment changes and seizure outcomes on depression and suicidality in adults with drug-resistant focal epilepsy.
Epilepsia. 2023 Dec 11. doi: 10.1111/epi.17856.
PubMed Abstract available

KIM SH, Seo J, Kwon SS, Teng LY, et al
Common genes and recurrent causative variants in 957 Asian patients with pediatric epilepsy.
Epilepsia. 2023 Dec 10. doi: 10.1111/epi.17857.
PubMed Abstract available

HANSEN D, Shandley S, Olaya J, Hauptman J, et al
A Multi-center Comparison of Surgical Technique for Corpus Callosotomy in Pediatric Drug Resistant Epilepsy.
Epilepsia. 2023 Dec 7. doi: 10.1111/epi.17853.
PubMed Abstract available

HADADY L, Sperling MR, Alcala-Zermeno JL, French JA, et al
Prediction tools and risk stratification in epilepsy surgery.
Epilepsia. 2023 Dec 7. doi: 10.1111/epi.17851.
PubMed Abstract available

NDODE-EKANE XE, Ali I, Santana Gomez C, Andrade P, et al
Epilepsy Phenotype and Its Reproducibility After Lateral Fluid-Percussion -Induced Traumatic Brain Injury In Rats - A Multicenter EpiBioS4Rx Study Project 1.
Epilepsia. 2023 Dec 5. doi: 10.1111/epi.17838.
PubMed Abstract available

GUO D, Zhang B, Han L, Rensing NR, et al
Cerebral vascular and blood brain-barrier abnormalities in a mouse model of epilepsy and tuberous sclerosis complex.
Epilepsia. 2023 Dec 4. doi: 10.1111/epi.17848.
PubMed Abstract available

BRATU IF, Makhalova J, Garnier E, Medina Villalon S, et al
Permutation entropy-derived parameters to estimate the epileptogenic zone network.
Epilepsia. 2023 Dec 2. doi: 10.1111/epi.17849.
PubMed Abstract available

D'ORIO P, Squarza S, Revay M, Cardinale F, et al
Neurological morbidity of surgery for supra-sylvian operculo-insular epilepsy.
Epilepsia. 2023 Dec 2. doi: 10.1111/epi.17844.
PubMed Abstract available

ROTH J, Bergman L, Weil AG, Brunette-Clement T, et al
Added value of corpus callosotomy following vagus nerve stimulation in children with Lennox-Gastaut syndrome: A multicenter, multinational study.
Epilepsia. 2023;64:3205-3212.
PubMed Abstract available

NGUYEN TD, Ishibashi M, Sinha AS, Watanabe M, et al
Astrocytic NKCC1 inhibits seizures by buffering Cl(-) and antagonizing neuronal NKCC1 at GABAergic synapses.
Epilepsia. 2023;64:3389-3403.
PubMed Abstract available

DE STEFANO P, Menetre E, Stancu P, Megevand P, et al
Added value of advanced workup after the first seizure: A 7-year cohort study.
Epilepsia. 2023;64:3246-3256.
PubMed Abstract available

BAUD MO, Rummel C
Introduction-Special issue ICTALS 2022.
Epilepsia. 2023;64 Suppl 3:S1-S2.
PubMed

JIRUSKA P, Freestone D, Gnatkovsky V, Wang Y, et al
An update on the seizures beget seizures theory.
Epilepsia. 2023;64 Suppl 3:S13-S24.
PubMed Abstract available

ANDRZEJAK RG, Zaveri HP, Schulze-Bonhage A, Leguia MG, et al
Seizure forecasting: Where do we stand?
Epilepsia. 2023;64 Suppl 3:S62-S71.
PubMed Abstract available

BRUNNHUBER F, Slater JD, Goyal S, Amin D, et al
The unforeseen future: Impacts of the COVID-19 pandemic on home video-EEG telemetry.
Epilepsia. 2023;64 Suppl 4:S12-S22.
PubMed Abstract available

LEGUIA MG, Rao VR, Tcheng TK, Duun-Henriksen J, et al
Learning to generalize seizure forecasts.
Epilepsia. 2023;64 Suppl 4:S99-S113.
PubMed Abstract available

CASTILLO RODRIGUEZ MLA, Brandt A, Schulze-Bonhage A
Differentiation of subclinical and clinical electrographic events in long-term electroencephalographic recordings.
Epilepsia. 2023;64 Suppl 4:S47-S58.
PubMed Abstract available

BAUD MO, Proix T, Gregg NM, Brinkmann BH, et al
Seizure forecasting: Bifurcations in the long and winding road.
Epilepsia. 2023;64 Suppl 4:S78-S98.
PubMed Abstract available

HARTMANN M, Koren J, Baumgartner C, Duun-Henriksen J, et al
Seizure detection with deep neural networks for review of two-channel electroencephalogram.
Epilepsia. 2023;64 Suppl 4:S34-S39.
PubMed Abstract available

VIANA PF, Pal Attia T, Nasseri M, Duun-Henriksen J, et al
Seizure forecasting using minimally invasive, ultra-long-term subcutaneous electroencephalography: Individualized intrapatient models.
Epilepsia. 2023;64 Suppl 4:S124-S133.
PubMed Abstract available

HADADY L, Klivenyi P, Fabo D, Beniczky S, et al
Real-world user experience with seizure detection wearable devices in the home environment.
Epilepsia. 2023;64 Suppl 4:S72-S77.
PubMed Abstract available

PELTOLA J, Basnyat P, Armand Larsen S, Osterkjaerhuus T, et al
Semiautomated classification of nocturnal seizures using video recordings.
Epilepsia. 2023;64 Suppl 4:S65-S71.
PubMed Abstract available

JAPARIDZE G, Loeckx D, Buckinx T, Armand Larsen S, et al
Automated detection of absence seizures using a wearable electroencephalographic device: a phase 3 validation study and feasibility of automated behavioral testing.
Epilepsia. 2023;64 Suppl 4:S40-S46.
PubMed Abstract available

November 2023

ALSHAKHOURI M, Sharpe C, Bergin P, Sumner RL, et al
Female Sex Steroids and Epilepsy Part 1: A Review of Reciprocal Changes in Reproductive Systems, Cycles, and Seizures.
Epilepsia. 2023 Nov 30. doi: 10.1111/epi.17842.
PubMed Abstract available

NG AC, Choudhary A, Barrett KT, Gavrilovici C, et al
Mechanisms of Infantile Epileptic Spasms Syndrome: What Have We Learnt From Animal Models?
Epilepsia. 2023 Nov 30. doi: 10.1111/epi.17841.
PubMed Abstract available

SWINNEN L, Chatzichristos C, Bhagubai M, Broux V, et al
Home recording of 3 Hz spike-wave discharges in adults with absence epilepsy using the wearable Sensor Dot.
Epilepsia. 2023 Nov 30. doi: 10.1111/epi.17839.
PubMed Abstract available

BELLO ST, Xu S, Li X, Ren J, et al
Visually or auditorily induced seizures involve the activation of nonhippocampal brain areas and hippocampal removal does not alleviate seizures in a mouse model of temporal lobe epilepsy.
Epilepsia. 2023 Nov 30. doi: 10.1111/epi.17816.
PubMed Abstract available

CASILLAS-ESPINOSA PM, Lin R, Li R, Powell KL, et al
Transmembrane AMPA receptor regulatory proteins expression during the development of absence seizures in the Genetic Absence Epilepsy Rats from Strasbourg.
Epilepsia. 2023 Nov 30. doi: 10.1111/epi.17837.
PubMed Abstract available

STEFANOS-YAKOUB I, Wingeier K, Held U, Latal B, et al
Long-Term Intellectual and Developmental Outcomes After Pediatric Epilepsy Surgery: A Systematic Review and Meta-Analysis.
Epilepsia. 2023 Nov 29. doi: 10.1111/epi.17834.
PubMed Abstract available

GUIGNET M, Vuong J, Martinez A, Ballapapinan T, et al
Temporal relationship between levetiracetam nonadherence and breakthrough seizures in a preclinical model of temporal lobe epilepsy.
Epilepsia. 2023 Nov 29. doi: 10.1111/epi.17835.
PubMed Abstract available

Correction to "Perampanel as precision therapy in rare genetic epilepsies".
Epilepsia. 2023 Nov 28. doi: 10.1111/epi.17832.
PubMed

REN T, Li Y, Burgess M, Sharma S, et al
Long-term physical and psychiatric morbidities and mortality of untreated, deferred, and immediately treated epilepsy.
Epilepsia. 2023 Nov 28. doi: 10.1111/epi.17819.
PubMed Abstract available

YU H, Kim W, Park DK, Phi JH, et al
Interaction of interictal epileptiform activity with sleep spindles is associated with cognitive deficits and adverse surgical outcome in pediatric focal epilepsy.
Epilepsia. 2023 Nov 20. doi: 10.1111/epi.17810.
PubMed Abstract available

KNIGHT A, Gschwind T, Galer P, Worrell GA, et al
Artificial Intelligence in Epilepsy Phenotyping.
Epilepsia. 2023 Nov 20. doi: 10.1111/epi.17833.
PubMed Abstract available

ASADI-POOYA AA
Drug resistance in epilepsy: A reappraisal of the definition is needed.
Epilepsia. 2023 Nov 15. doi: 10.1111/epi.17814.
PubMed

MISIROCCHI F, Zilioli A, Mannini E, Lazzari S, et al
Prognostic value of nonconvulsive status epilepticus Salzburg criteria: The sace score.
Epilepsia. 2023 Nov 15. doi: 10.1111/epi.17830.
PubMed Abstract available

KARIUKI SM, Wagner RG, Gunny R, D'Arco F, et al
Magnetic Resonance Imaging Findings in Kenyans and South Africans with Active Convulsive Epilepsy: An Observational Study.
Epilepsia. 2023 Nov 14. doi: 10.1111/epi.17829.
PubMed Abstract available

BRISCOE ABATH C, Gupta N, Hadjinicolaou A, Donatelli S, et al
Delays to Care in Infantile Epileptic Spasms Syndrome: racial and ethnic inequities.
Epilepsia. 2023 Nov 12. doi: 10.1111/epi.17827.
PubMed Abstract available

ALSHAKHOURI M, Sharpe C, Bergin P, Sumner RL, et al
Female Sex Steroids and Epilepsy Part 2: A Practical and Human Focus on Catamenial Epilepsy.
Epilepsia. 2023 Nov 4. doi: 10.1111/epi.17820.
PubMed Abstract available

GALANOPOULOU AS, Auvin S, Moshe SL, Potschka H, et al
Response: Drug resistance in epilepsy: a reappraisal of the definition is needed.
Epilepsia. 2023 Nov 3. doi: 10.1111/epi.17818.
PubMed

BENICZKY S, Ryvlin P
Mobile health and digital technology in epilepsy: the dawn of a new era.
Epilepsia. 2023 Nov 3. doi: 10.1111/epi.17813.
PubMed

BEUCHAT I, Novy J, Rosenow F, Kellinghaus C, et al
Staged treatment response in Status epilepticus - Lessons from the SENSE registry.
Epilepsia. 2023 Nov 1. doi: 10.1111/epi.17817.
PubMed Abstract available

ENGLOT DJ
Epilepsy Surgery is Not Palliative.
Epilepsia. 2023 Nov 1. doi: 10.1111/epi.17815.
PubMed

SCOTT RC, Moshe SL, Holmes GL
Do Vaccines Cause Epilepsy? Review of Cases in The National Vaccine Injury Compensation Program.
Epilepsia. 2023 Nov 1. doi: 10.1111/epi.17794.
PubMed Abstract available

AUDRAIN S, Barnett A, Mouseli P, McAndrews MP, et al
Leveraging the resting brain to predict memory decline after temporal lobectomy.
Epilepsia. 2023;64:3061-3072.
PubMed Abstract available

BRUNKLAUS A, George AL Jr, Lal D, Heinzen EL, et al
Prophecy or empiricism? Clinical value of predicting versus determining genetic variant functions.
Epilepsia. 2023;64:2909-2913.
PubMed Abstract available

LATTANZI S, Canafoglia L, Canevini MP, Casciato S, et al
Adjunctive brivaracetam and sustained seizure frequency reduction in very active focal epilepsy.
Epilepsia. 2023;64:2922-2933.
PubMed Abstract available

October 2023

IZUMI M, Kobayashi K, Kajikawa S, Kanazawa K, et al
Focal ictal direct current shifts by a time constant of 2 seconds were clinically useful for resective epilepsy surgery.
Epilepsia. 2023 Oct 31. doi: 10.1111/epi.17782.
PubMed Abstract available

SETH J, Couper RG, Burneo JG, Suller Marti A, et al
The effects of vagus nerve stimulation on the quality of sleep and sleep apnea in patients with drug-resistant epilepsy: A systematic review.
Epilepsia. 2023 Oct 29. doi: 10.1111/epi.17811.
PubMed Abstract available

GOEL K, Phillips HW, Chen JS, Ngo J, et al
Hemispheric Epilepsy Surgery for Hemimegalencephaly: The UCLA Experience.
Epilepsia. 2023 Oct 24. doi: 10.1111/epi.17807.
PubMed Abstract available

CERULLI IRELLI E, Gesche J, Schlabitz S, Fortunato F, et al
Epilepsy with generalized tonic-clonic seizures alone: electroclinical features and prognostic patterns.
Epilepsia. 2023 Oct 23. doi: 10.1111/epi.17809.
PubMed Abstract available

KUCHENBUCH M, Lo Barco T, Chemaly N, Chiron C, et al
15 years of real-world data on the use of vigabatrin in individuals with infantile epileptic spasm syndrome.
Epilepsia. 2023 Oct 23. doi: 10.1111/epi.17808.
PubMed Abstract available

LAAKSONEN J, Ponkilainen V, Kuitunen I, Mottonen J, et al
Association Between Pediatric Traumatic Brain Injury and Epilepsy at Later Ages in Finland - a Nationwide Register-based Cohort Study.
Epilepsia. 2023 Oct 23. doi: 10.1111/epi.17805.
PubMed Abstract available

FEYS O, Wens V, Corvilain P, Ferez M, et al
Where do we stand exactly with on-scalp magnetoencephalography in the presurgical evaluation of refractory focal epilepsy?
Epilepsia. 2023 Oct 20. doi: 10.1111/epi.17806.
PubMed

LATTANZI S, Trinka E, Meletti S
Which is the risk of unprovoked seizures after acute symptomatic status epilepticus?
Epilepsia. 2023 Oct 19. doi: 10.1111/epi.17792.
PubMed

ZEICU C, Legouhy A, Scott CA, Oliveira JFA, et al
Altered Amygdala Volumes and Microstructure in Focal Epilepsy Patients with Tonic-Clonic Seizures, Ictal and Post-convulsive central apnea.
Epilepsia. 2023 Oct 19. doi: 10.1111/epi.17804.
PubMed Abstract available

FOX J, Barnard S, Agashe SH, Holmes MG, et al
Patterns of Anti-Seizure Medication Utilization in the Human Epilepsy Project (HEP).
Epilepsia. 2023 Oct 17. doi: 10.1111/epi.17802.
PubMed Abstract available

SMITH ML, Puka K, Speechley KN, Ferro MA, et al
Trajectories of Parent Well-Being in Children with Drug-Resistant Epilepsy.
Epilepsia. 2023 Oct 12. doi: 10.1111/epi.17797.
PubMed Abstract available

BINGAMAN N, Ferguson L, Thompson N, Reyes A, et al
The Relationship between Mood and Anxiety and Cognitive Phenotypes in Adults with Pharmacoresistant Temporal Lobe Epilepsy.
Epilepsia. 2023 Oct 9. doi: 10.1111/epi.17795.
PubMed Abstract available

YARDI AR, McLouth CJ, Mathias S, Jehi L, et al
Telemedicine as a path to bridging inequities in patients with Epilepsy.
Epilepsia. 2023 Oct 9. doi: 10.1111/epi.17793.
PubMed Abstract available

REILLY C, Jette N, Johnson EC, Kariuki SM, et al
Scoping review and expert-based consensus recommendations for assessment and management of psychogenic non-epileptic (functional) seizures (PNES) in children: A report from the Pediatric Psychiatric Issues Task Force of the International League Agains
Epilepsia. 2023 Oct 7. doi: 10.1111/epi.17768.
PubMed Abstract available

CHAFJIRI FMA, Reece L, Voke L, Landschaft A, et al
Natural Language Processing for Identification of Refractory Status Epilepticus in Children.
Epilepsia. 2023 Oct 7. doi: 10.1111/epi.17789.
PubMed Abstract available

SANTAMARINA E, Rodrigo-Gisbert M, Abraira L, Campos-Fernandez D, et al
Response: "Which is the risk of unprovoked seizures after acute symptomatic status epilepticus?".
Epilepsia. 2023 Oct 7. doi: 10.1111/epi.17790.
PubMed

RAINER LJ, Kuchukhidze G, Trinka E, Braun M, et al
Recognition and Perception of Emotions in Juvenile Myoclonic Epilepsy.
Epilepsia. 2023 Oct 5. doi: 10.1111/epi.17783.
PubMed Abstract available

MORRIS G, Avoli M, Bernard C, Connor K, et al
Can in vitro studies aid in the development and use of antiseizure therapies? A report of the ILAE/AES Joint Translational Task Force.
Epilepsia. 2023;64:2571-2585.
PubMed Abstract available

PIPATPRATARNPORN W, Muangthong W, Jirasakuldej S, Limotai C, et al
Wrist-worn smartwatch and predictive models for seizures.
Epilepsia. 2023;64:2701-2713.
PubMed Abstract available

KERR WT, Reddy AS, Seo SH, Kok N, et al
Increasing challenges to trial recruitment and conduct over time.
Epilepsia. 2023;64:2625-2634.
PubMed Abstract available

PRESSLER RM, Abend NS, Auvin S, Boylan G, et al
Treatment of seizures in the neonate: Guidelines and consensus-based recommendations-Special report from the ILAE Task Force on Neonatal Seizures.
Epilepsia. 2023;64:2550-2570.
PubMed Abstract available

September 2023

SILVA AB, Leonard MK, Oganian Y, D'Esopo E, et al
Interictal epileptiform discharges contribute to word-finding difficulty in epilepsy through multiple cognitive mechanisms.
Epilepsia. 2023 Sep 27. doi: 10.1111/epi.17781.
PubMed Abstract available

JOHANNESEN KM, Tumer Z, Weckhuysen S, Barakat TS, et al
Solving the unsolved genetic epilepsies - current and future perspectives.
Epilepsia. 2023 Sep 26. doi: 10.1111/epi.17780.
PubMed Abstract available

DIFRANCESCO JC, Ragona F, Murano C, Frosio A, et al
A novel de novo HCN2 loss-of-function variant causing developmental and epileptic encephalopathy treated with ketogenic diet.
Epilepsia. 2023 Sep 25. doi: 10.1111/epi.17777.
PubMed Abstract available

COHEN NT, Xie H, Gholipour T, Gaillard WD, et al
A scoping review of the fMRI-based functional connectivity of FCD-related epilepsy.
Epilepsia. 2023 Sep 20. doi: 10.1111/epi.17775.
PubMed Abstract available

BAGIC AI, Bowyer SM, Burgess RC, Funke ME, et al
The Role of Optically Pumped Magnetometers (OPMs) in Pre-surgical Epilepsy Evaluation Commentary of the American Clinical Magnetoencephalography Society (ACMEGS).
Epilepsia. 2023 Sep 20. doi: 10.1111/epi.17770.
PubMed

GOTLIEB EG, Blank L, Willis AW, Agarwal P, et al
Health equity integrated epilepsy care and research: A narrative review.
Epilepsia. 2023 Sep 19. doi: 10.1111/epi.17728.
PubMed Abstract available

YU S, El Atrache R, Tang J, Jackson M, et al
Artificial Intelligence Enhanced Epileptic Seizure Detection from Wearables.
Epilepsia. 2023 Sep 15. doi: 10.1111/epi.17774.
PubMed Abstract available

HO A, Hannan S, Thomas J, Avigdor T, et al
Rapid eye movement sleep affects interictal epileptic activity differently in mesiotemporal and neocortical areas.
Epilepsia. 2023 Sep 15. doi: 10.1111/epi.17763.
PubMed Abstract available

HANSEN SN, Holm A, Kauppinen S, Klitgaard H, et al
RNA therapeutics for epilepsy: an emerging modality for drug discovery.
Epilepsia. 2023 Sep 13. doi: 10.1111/epi.17772.
PubMed Abstract available

AUVIN S, Galanopoulou AS, Moshe SL, Potschka H, et al
Revisiting the concept of drug-resistant epilepsy: A TASK1 report of the ILAE/AES Joint Translational Task Force.
Epilepsia. 2023 Sep 7. doi: 10.1111/epi.17751.
PubMed Abstract available

STILLEY SE, Naraine AS, Yadavalli KP, Maki SL, et al
Bridged Bicyclic Compounds: Comprehending a Novel Compound Class as Potential Anti-Epileptic Agents.
Epilepsia. 2023 Sep 3. doi: 10.1111/epi.17769.
PubMed Abstract available

ABOUKAOUD M, Wilf-Yarkoni A, Maor E
Investigation of cardiac arrhythmia events in patients treated with lamotrigine: FDA adverse event reporing system analysis.
Epilepsia. 2023;64:2322-2329.
PubMed Abstract available

SAINJU RK, Dragon DN, Winnike HB, Vilella L, et al
Interictal respiratory variability predicts severity of hypoxemia after generalized convulsive seizures.
Epilepsia. 2023;64:2373-2384.
PubMed Abstract available

GARCAO VM, Abreu M, Peralta AR, Bentes C, et al
A novel approach to automatic seizure detection using computer vision and independent component analysis.
Epilepsia. 2023;64:2472-2483.
PubMed Abstract available

August 2023

FONFERKO-SHADRACH B, Lacey AS, Strafford H, Jones C, et al
Genetic influences on epilepsy outcomes: a whole-exome sequencing and healthcare records data linkage study.
Epilepsia. 2023 Aug 29. doi: 10.1111/epi.17766.
PubMed Abstract available

SIOUTAS GS, Palepu C, Salem MM, Nia AM, et al
Postoperative de novo epilepsy after resection of brain arteriovenous malformations: a national database study of 536 patients.
Epilepsia. 2023 Aug 28. doi: 10.1111/epi.17765.
PubMed Abstract available

PETERS JM, Becker DA, Verma A, Sirven J, et al
Comment on: Failure to use new breakthrough treatments for epilepsy.
Epilepsia. 2023 Aug 27. doi: 10.1111/epi.17764.
PubMed

KINNEY MO, Delanty N
Dose of folic acid supplementation in Women with Epilepsy: recent controversies.
Epilepsia. 2023 Aug 25. doi: 10.1111/epi.17762.
PubMed

FUKUMA K, Tojima M, Tanaka T, Kobayashi K, et al
Periodic discharges plus fast activity on EEG predict worse outcomes in post-stroke epilepsy.
Epilepsia. 2023 Aug 23. doi: 10.1111/epi.17760.
PubMed Abstract available

TOKATLY LATZER I, Richmond T, Zhang B, Pearl PL, et al
Eating disorders occur at high rates in adolescents with epilepsy and are associated with psychiatric comorbidities and suicidality.
Epilepsia. 2023 Aug 23. doi: 10.1111/epi.17759.
PubMed Abstract available

LI Y, Liu P, Lin Q, Zhou D, et al
Postoperative seizure and memory outcome of temporal lobe epilepsy with hippocampal sclerosis: A systematic review.
Epilepsia. 2023 Aug 23. doi: 10.1111/epi.17757.
PubMed Abstract available

EISELE A, Schwager M, Bogli SY, Reichen I, et al
The role of neuronal antibodies in cryptogenic new-onset refractory status epilepticus.
Epilepsia. 2023 Aug 22. doi: 10.1111/epi.17755.
PubMed Abstract available

YANG AI, Raghu ALB, Isbaine F, Alwaki A, et al
Sensing with deep brain stimulation device in epilepsy: aperiodic changes in thalamic local field potential during seizures.
Epilepsia. 2023 Aug 22. doi: 10.1111/epi.17758.
PubMed Abstract available

PROOST R, Macea J, Lagae L, Van Paesschen W, et al
Wearable detection of tonic seizures in childhood epilepsy: an exploratory cohort study.
Epilepsia. 2023 Aug 21. doi: 10.1111/epi.17756.
PubMed

LAGAE L, Klotz KA, Fogarasi A, Floricel F, et al
Long-term safety and efficacy of adjunctive brivaracetam in pediatric patients with epilepsy: An open-label, follow-up trial.
Epilepsia. 2023 Aug 19. doi: 10.1111/epi.17754.
PubMed Abstract available

LATTANZI S, Giovannini G, Brigo F, Orlandi N, et al
Acute symptomatic status epilepticus: splitting or lumping? A proposal of classification based on real-world data.
Epilepsia. 2023 Aug 19. doi: 10.1111/epi.17753.
PubMed Abstract available

MOREIRA AB, Knochenhauer AE, Froehner GV, Schwarzbold ML, et al
Prevalence of ictal injuries in functional (psychogenic non-epileptic) seizures: A systematic review and meta-analysis.
Epilepsia. 2023 Aug 19. doi: 10.1111/epi.17752.
PubMed Abstract available

ABDUL RAZAQ AA, Ainsworth AJ, Britton JW, Shenoy CC, et al
Seizure control in women with epilepsy undergoing assisted reproductive technology.
Epilepsia. 2023 Aug 19. doi: 10.1111/epi.17748.
PubMed Abstract available

SKLENAROVA B, Zatloukalova E, Cimbalnik J, Klimes P, et al
Interictal High-Frequency Oscillations, Spikes, and Connectivity Profiles: a Fingerprint of Epileptogenic Brain Pathologies.
Epilepsia. 2023 Aug 17. doi: 10.1111/epi.17749.
PubMed Abstract available

CHUNG KM, Hack J, Andrews J, Galindo-Kelly M, et al
Clinical severity is correlated with age at seizure onset and biophysical properties of recurrent gain of function variants associated with SCN8A-related epilepsy.
Epilepsia. 2023 Aug 16. doi: 10.1111/epi.17747.
PubMed Abstract available

LIU N, Li J, Gao K, Perszyk RE, et al
De novo CLPTM1 variants with reduced GABA(A) R current response in patients with epilepsy.
Epilepsia. 2023 Aug 14. doi: 10.1111/epi.17746.
PubMed Abstract available

VULPIUS SA, Werge S, Jorgensen IF, Siggaard T, et al
Text mining of electronic health records can validate a register-based diagnosis of epilepsy and subgroup into focal and generalized epilepsy.
Epilepsia. 2023 Aug 7. doi: 10.1111/epi.17734.
PubMed Abstract available

CHAN H, Janssen LMM, Wijnen BFM, Hiligsmann M, et al
Economic evaluations of non-pharmacological treatments for drug-resistant epilepsy: A systematic review.
Epilepsia. 2023 Aug 7. doi: 10.1111/epi.17742.
PubMed Abstract available

AUVIN S, Arzimanoglou A, Beller C, Floricel F, et al
Safety, tolerability, and efficacy of adjunctive lacosamide in pediatric patients with epilepsy syndromes associated with generalized seizures: Phase 2, open-label exploratory trial.
Epilepsia. 2023 Aug 7. doi: 10.1111/epi.17741.
PubMed Abstract available

AUNG T, Grinenko O, Li J, Mosher JC, et al
Stereo-electroencephalography Guided Laser Ablation in Neocortical Epilepsy: Electrophysiological correlations and Outcome.
Epilepsia. 2023 Aug 7. doi: 10.1111/epi.17739.
PubMed Abstract available

DE DIEGO-GARCIA L, Brennan GP, Auer T, Menendez-Mendez A, et al
CPEB4 - CLOCK crosstalk during temporal lobe epilepsy.
Epilepsia. 2023 Aug 6. doi: 10.1111/epi.17736.
PubMed Abstract available

ALI I, Silva J, Casillas-Espinosa PM, Braine E, et al
E2730, an uncompetitive GABA transporter-1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy.
Epilepsia. 2023 Aug 4. doi: 10.1111/epi.17735.
PubMed Abstract available

SHEARER J, Scantlebury MH, Rho JM, Tompkins TA, et al
Intermittent vs continuous ketogenic diet: Impact on seizures, gut microbiota, and mitochondrial metabolism.
Epilepsia. 2023;64:e177-e183.
PubMed Abstract available

OYEGBILE-CHIDI T, Harvey D, Jones J, Byars A, et al
Impact of sociodemographic disadvantage on neurobehavioral outcomes in children with newly diagnosed seizures and their unaffected siblings over 36 months.
Epilepsia. 2023;64:2172-2185.
PubMed Abstract available

FONG SL, Thuy Le MA, Lim KS, Khosama H, et al
Affordability of newer antiseizure medications in Asian resource-limited countries.
Epilepsia. 2023;64:2116-2125.
PubMed Abstract available

PETERSON V, Kokkinos V, Ferrante E, Walton A, et al
Deep net detection and onset prediction of electrographic seizure patterns in responsive neurostimulation.
Epilepsia. 2023;64:2056-2069.
PubMed Abstract available

BUENZLI JC, Werth E, Baumann CR, Belvedere A, et al
Deep brain stimulation of the anterior nucleus of the thalamus increases slow wave activity in non-rapid eye movement sleep.
Epilepsia. 2023;64:2044-2055.
PubMed Abstract available

SINGH V, Ryan JM, Auerbach DS
It is premature for a unified hypothesis of sudden unexpected death in epilepsy: A great amount of research is still needed to understand the multisystem cascade.
Epilepsia. 2023;64:2006-2010.
PubMed

July 2023

SHI XY, Ju J, Lu Q, Hu LY, et al
Both epilepsy and anti-seizure medications affect bone metabolism in children with self-limited epilepsy with centrotemporal spikes.
Epilepsia. 2023 Jul 31. doi: 10.1111/epi.17733.
PubMed Abstract available

PELLINEN J, Pardoe H, Sillau S, Barnard S, et al
Later Onset Focal Epilepsy with Roots in Childhood: Evidence from Early Learning Difficulty and Brain Volumes in the Human Epilepsy Project.
Epilepsia. 2023 Jul 30. doi: 10.1111/epi.17727.
PubMed Abstract available

BOLLING-LADEGAARD E, Dreier JW, Christensen J
Identification of Drug Resistance in a Validated Cohort of Incident Epilepsy Patients in the Danish National Patient Register.
Epilepsia. 2023 Jul 28. doi: 10.1111/epi.17732.
PubMed Abstract available

GOLDENHOLZ DM, Goldenholz EB, Kaptchuk TJ
Quantifying and controlling the impact of regression to the mean on randomized controlled trials in epilepsy.
Epilepsia. 2023 Jul 28. doi: 10.1111/epi.17730.
PubMed Abstract available

LINDQUIST BE, Voskobiynyk Y, Goodspeed K, Paz JT, et al
Patient-derived SLC6A1 variant S295L results in an epileptic phenotype similar to haploinsufficient mice.
Epilepsia. 2023 Jul 28. doi: 10.1111/epi.17731.
PubMed Abstract available

BARBOUR K, Tian N, Yozawitz EG, Wolf S, et al
Creating rare epilepsy cohorts using keyword search in electronic health records.
Epilepsia. 2023 Jul 27. doi: 10.1111/epi.17725.
PubMed Abstract available

MOLISANI SE, Parikh D, DiGiovine M, Dlugos D, et al
A quality improvement initiative to improve folic acid supplementation counseling for adolescent females with epilepsy.
Epilepsia. 2023 Jul 27. doi: 10.1111/epi.17723.
PubMed Abstract available

CHUA MMJ, Vissani M, Liu DD, Schaper FLWVJ, et al
Initial case series of a novel sensing deep brain stimulation device in drug-resistant epilepsy and consistent identification of alpha/beta oscillatory activity: A feasibility study.
Epilepsia. 2023 Jul 22. doi: 10.1111/epi.17722.
PubMed Abstract available

CACIAGLI L, Ratcliffe C, Xiao F, van Graan LA, et al
The cognitive phenotype of juvenile absence epilepsy: An investigation of patients and unaffected siblings.
Epilepsia. 2023 Jul 21. doi: 10.1111/epi.17719.
PubMed Abstract available

AKEL S, Asztely F, Banote RK, Axelsson M, et al
Neurofilament light, glial fibrillary acidic protein, and tau in a regional epilepsy cohort: High plasma levels are rare but related to seizures.
Epilepsia. 2023 Jul 19. doi: 10.1111/epi.17713.
PubMed Abstract available

RUBBOLI G, Valzania F
Transcranial magnetic stimulation in progressive myoclonus epilepsy: A promising tool for "deep phenotyping" in genetic epilepsies.
Epilepsia. 2023 Jul 15. doi: 10.1111/epi.17572.
PubMed

VOINESCU PE, Kelly M, French JA, Harden C, et al
Catamenial epilepsy occurence and patterns in a mixed population of women with epilepsy.
Epilepsia. 2023 Jul 15. doi: 10.1111/epi.17718.
PubMed Abstract available

UFONGENE C, Van Hyfte G, Agarwal P, Blank LJ, et al
In-hospital outcomes in patients with and without epilepsy diagnosed with COVID-19 - A cohort study.
Epilepsia. 2023 Jul 15. doi: 10.1111/epi.17715.
PubMed Abstract available

LARSSON D, Mroue D, Andren K, Zelano J, et al
Antiseizure medication selection and retention for adult-onset focal epilepsy in a Swedish health service region: a population-based cohort study.
Epilepsia. 2023 Jul 8. doi: 10.1111/epi.17711.
PubMed Abstract available

DELGADO-GARCIA G, Engbers JDT, Wiebe S, Mouches P, et al
Machine learning using multimodal clinical, electroencephalographic, and magnetic resonance imaging data can predict incident depression in adults with epilepsy: A pilot study.
Epilepsia. 2023 Jul 8. doi: 10.1111/epi.17710.
PubMed Abstract available

BROMLEY RL, Bullen P, Campbell E, Craig J, et al
Neurodevelopment of babies born to mothers with epilepsy: a prospective observational cohort study.
Epilepsia. 2023 Jul 5. doi: 10.1111/epi.17709.
PubMed Abstract available

MIKATI M
Quality of Life After Epilepsy Surgery: Study Designs and Outcome Assessments.
Epilepsia. 2023 Jul 1. doi: 10.1111/epi.17706.
PubMed

SARKIS RA, Lam AD, Pavlova M, Locascio JJ, et al
Epilepsy and Sleep Characteristics Are Associated with Diminished 24-Hour Memory Retention in Older Adults with Epilepsy.
Epilepsia. 2023 Jul 1. doi: 10.1111/epi.17707.
PubMed Abstract available

BOGLI SY, Schmidt T, Imbach LL, Nellessen F, et al
Non-Convulsive Status Epilepticus in Neurocritical Care: A Critical Reappraisal of Outcome Prediction Scores.
Epilepsia. 2023 Jul 1. doi: 10.1111/epi.17708.
PubMed Abstract available

GANDY M, Michaelis R, Acraman J, Donald KA, et al
Integrated psychological care services within seizure settings: Key components and implementation factors among example services in four ILAE regions: A report by the ILAE Psychiatry Commission.
Epilepsia. 2023;64:1766-1784.
PubMed Abstract available

TALAVERA B, Chaitanya G, Hupp N, Pati S, et al
Stimulation-induced respiratory enhancement in corticothalamic regions.
Epilepsia. 2023;64:1925-1938.
PubMed Abstract available

KALBHENN T, Cloppenborg T, Woermann FG, Hagemann A, et al
Hemispherotomy in children: A retrospective analysis of 152 surgeries at a single center and predictors for long-term seizure outcome.
Epilepsia. 2023;64:1800-1811.
PubMed Abstract available

FAHOUM F, Eyal S
Intracerebroventricular administration for delivery of antiseizure therapeutics: Challenges and opportunities.
Epilepsia. 2023;64:1750-1765.
PubMed Abstract available

KERR WT, Auvin S, Van der Geyten S, Kenney C, et al
Time-to-event clinical trial designs: Existing evidence and remaining concerns.
Epilepsia. 2023;64:1699-1708.
PubMed Abstract available

AUVIN S, Nortvedt C, Fuller DS, Sahebkar F, et al
Seizure-free days as a novel outcome in patients with Lennox-Gastaut syndrome: Post hoc analysis of patients receiving cannabidiol in two randomized controlled trials.
Epilepsia. 2023;64:1812-1820.
PubMed Abstract available

June 2023

FAINGOLD CL, Feng HJ
Response to Singh et al. 2023: It is premature for a unified hypothesis of sudden unexpected death in epilepsy: A great amount of research is still needed to understand the multisystem cascade.
Epilepsia. 2023 Jun 29. doi: 10.1111/epi.17698.
PubMed Abstract available

DE STEFANO P, Sutter R
Response: Letter to the editor regarding "Early timing of anesthesia in status epilepticus is associated with complete recovery: A 7-year retrospective two-center study". doi: 10.1111/epi.17614.
Epilepsia. 2023 Jun 28. doi: 10.1111/epi.17703.
PubMed

ALVAREZ V, Novy J, Beuchat I, Rossetti AO, et al
Letter to the editor regarding "Early timing of anesthesia in status epilepticus is associated with complete recovery: A 7-year retrospective two-center study".
Epilepsia. 2023 Jun 27. doi: 10.1111/epi.17705.
PubMed

CHU DY, Adluru N, Nair VA, Choi T, et al
Association of Neighborhood Deprivation with White Matter Connectome Abnormalities in Temporal Lobe Epilepsy.
Epilepsia. 2023 Jun 27. doi: 10.1111/epi.17702.
PubMed Abstract available

KWACK DW, Kim DW
Potential efficacy and safety of eslicarbazepine acetate oral loading in patients with epilepsy.
Epilepsia. 2023 Jun 27. doi: 10.1111/epi.17704.
PubMed Abstract available

PEKOZ MT, Aslan-Kara K, Tekin B, Gurses C, et al
Birth Outcomes in Pregnant Women with Epilepsy: a Nationwide Multicenter Study from Turkiye.
Epilepsia. 2023 Jun 25. doi: 10.1111/epi.17692.
PubMed Abstract available

TRUJILLO S, Wetmore JB, Camarillo IA, Misiewicz S, et al
Knowledge and Beliefs about Epilepsy Genetics among Hispanic and Non-Hispanic Patients.
Epilepsia. 2023 Jun 24. doi: 10.1111/epi.17701.
PubMed Abstract available

LEITINGER M, Gaspard N, Hirsch LJ, Beniczky S, et al
Diagnosing nonconvulsive status epilepticus: defining EEG and clinical response to diagnostic intravenous anti-seizure medication trials.
Epilepsia. 2023 Jun 23. doi: 10.1111/epi.17694.
PubMed Abstract available

BRANDEL MG, Kunwar N, Alattar AA, Kang KM, et al
A Cost Analysis of MR-Guided Laser Interstitial Thermal Therapy for Adult Refractory Epilepsy.
Epilepsia. 2023 Jun 23. doi: 10.1111/epi.17693.
PubMed Abstract available

RADA A, Bien CG
What is autoimmune encephalitis-associated epilepsy? Proposal of a practical definition.
Epilepsia. 2023 Jun 23. doi: 10.1111/epi.17699.
PubMed

CHANG P, Xie H, Illapani VSP, You X, et al
Focal to Bilateral Tonic-Clonic Seizures Predict Pharmacoresistance in Focal Cortical Dysplasia-Related Epilepsy.
Epilepsia. 2023 Jun 22. doi: 10.1111/epi.17700.
PubMed Abstract available

RODRIGO-GISBERT M, Gomez-Dabo L, Quintana M, Campos-Fernandez D, et al
Prediction of long-term unprovoked seizures after status epilepticus.
Epilepsia. 2023 Jun 22. doi: 10.1111/epi.17697.
PubMed Abstract available

DALLMER-ZERBE I, Jiruska P, Hlinka J
Personalized dynamic network models of the human brain as a future tool for planning and optimizing epilepsy therapy.
Epilepsia. 2023 Jun 20. doi: 10.1111/epi.17690.
PubMed Abstract available

MALAGA I, Avila A, Primeaux S, Park JY, et al
A concise study of acetazolamide in Glut1 deficiency (G1D) epilepsy.
Epilepsia. 2023 Jun 19. doi: 10.1111/epi.17684.
PubMed Abstract available

SMITH KM, Wirrell EC, Andrade DM, Choi H, et al
Management of epilepsy with eyelid myoclonia: results of an international expert consensus panel.
Epilepsia. 2023 Jun 16. doi: 10.1111/epi.17682.
PubMed Abstract available

ELAMIN M, Lemtiri-Chlieh F, Robinson TM, Levine ES, et al
Dysfunctional sodium channel kinetics as a novel epilepsy mechanism in chromosome 15q11-q13 duplication syndrome.
Epilepsia. 2023 Jun 16. doi: 10.1111/epi.17687.
PubMed Abstract available

FIALHO GL, Pang TD, Kong WY, Tran AP, et al
Individuals with Chronic Epilepsy Have Elevated P-Wave Heterogeneity Comparable to Patients with Atrial Fibrillation.
Epilepsia. 2023 Jun 16. doi: 10.1111/epi.17686.
PubMed Abstract available

SMITH KM, Wirrell EC, Andrade DM, Choi H, et al
Clinical presentation and evaluation of epilepsy with eyelid myoclonia: results of an international expert consensus panel.
Epilepsia. 2023 Jun 16. doi: 10.1111/epi.17683.
PubMed Abstract available

VON WREDE R, Witt JA, Auvin S, Devlin A, et al
Unjustified allegation on cancer risks in children of mothers with epilepsy taking high-dose folic acid during pregnancy - No proof of a causal relationship.
Epilepsia. 2023 Jun 13. doi: 10.1111/epi.17680.
PubMed

CUI J, Balzekas I, Nurse E, Viana P, et al
Perceived seizure risk in epilepsy - Chronic electronic surveys with and without concurrent EEG.
Epilepsia. 2023 Jun 11. doi: 10.1111/epi.17678.
PubMed Abstract available

AUM DJ, Reynolds RA, McEvoy S, Tomko S, et al
Surgical Outcomes of Open and Laser interstitial thermal therapy (LITT) approaches for Corpus Callosotomy in Pediatric Epilepsy.
Epilepsia. 2023 Jun 11. doi: 10.1111/epi.17679.
PubMed Abstract available

SHIELDS JA, Greven ACM, Shivamurthy VKN, Dickey AS, et al
SEEG-guided radiofrequency ablation of the epileptogenic zone as a treatment and predictor of future success of further surgical intervention.
Epilepsia. 2023 Jun 10. doi: 10.1111/epi.17673.
PubMed Abstract available

CUSTERS ML, Vyver MV, Kaltenbock L, Barbe K, et al
Neurofilament light chain - a possible fluid biomarker in the intrahippocampal kainic acid mouse model for chronic epilepsy?
Epilepsia. 2023 Jun 2. doi: 10.1111/epi.17669.
PubMed Abstract available

JOMAA N, Nasreddine W, Hmeimess G, Beaini S, et al
Risk of Recurrence in Patients with an Unprovoked Tonic-Clonic Seizure and Generalized Epileptiform Discharges on EEG.
Epilepsia. 2023 Jun 2. doi: 10.1111/epi.17671.
PubMed Abstract available

ERIKSSON MH, Whitaker KJ, Booth J, Piper RJ, et al
Pediatric epilepsy surgery from 2000 to 2018: Changes in referral and surgical volumes, patient characteristics, genetic testing, and post-surgical outcomes.
Epilepsia. 2023 Jun 2. doi: 10.1111/epi.17670.
PubMed Abstract available

GREGG NM, Pal Attia T, Nasseri M, Joseph B, et al
Seizure occurrence is linked to multiday cycles in diverse physiological signals.
Epilepsia. 2023;64:1627-1639.
PubMed Abstract available

WHITNEY R, Jones KC, Sharma S, RamachandranNair R, et al
SUDEP counseling: Where do we stand?
Epilepsia. 2023;64:1424-1431.
PubMed Abstract available

MORO M, Pastore VP, Marchesi G, Proserpio P, et al
Automatic video analysis and classification of sleep-related hypermotor seizures and disorders of arousal.
Epilepsia. 2023;64:1653-1662.
PubMed Abstract available

MICHALAK AJ, Greenblatt A, Wu S, Tobochnik S, et al
Seizure onset patterns predict outcome after stereo-electroencephalography-guided laser amygdalohippocampotomy.
Epilepsia. 2023;64:1568-1581.
PubMed Abstract available

MATRICARDI S, Cesaroni E, Bonanni P, Foschi N, et al
Long-term effectiveness of add-on perampanel in patients with Lennox-Gastaut syndrome: A multicenter retrospective study.
Epilepsia. 2023;64:e98-e104.
PubMed Abstract available

RUSSO S, Mikulan E, Zauli FM, Sartori I, et al
Neocortical and medial temporal seizures have distinct impacts on brain responsiveness.
Epilepsia. 2023;64:e118-e126.
PubMed Abstract available

VAN DER KOP ML
The need for an individualized approach to what is considered a clinically significant reduction in seizure frequency: A patient's perspective.
Epilepsia. 2023;64:1469-1471.
PubMed

AUNGAROON G, Vedala K, Byars AW, Ervin B, et al
Comparing electrical stimulation functional mapping with subdural electrodes and stereoelectroencephalography.
Epilepsia. 2023;64:1527-1540.
PubMed Abstract available

May 2023

Correction to "Heterozygous GABA(A) receptor beta3 subunit N110D knock-in mice have epileptic spasms".
Epilepsia. 2023 May 28. doi: 10.1111/epi.17667.
PubMed

FLAMINI RJ, Comi AM, Bebin EM, Chez MG, et al
Efficacy of cannabidiol in convulsive and nonconvulsive seizure types associated with treatment-resistant epilepsies in the expanded access program.
Epilepsia. 2023 May 26. doi: 10.1111/epi.17665.
PubMed Abstract available

BERNARD C, Frauscher B, Gelinas J, Timofeev I, et al
Sleep, oscillations, and epilepsy.
Epilepsia. 2023 May 25. doi: 10.1111/epi.17664.
PubMed Abstract available

WANG Y, Schroeder GM, Horsley JJ, Panagiotopoulou M, et al
Temporal stability of intracranial EEG abnormality maps for localizing epileptogenic tissue.
Epilepsia. 2023 May 24. doi: 10.1111/epi.17663.
PubMed Abstract available

ROSENFELD WE, Ferrari L, Kerr WT, Sperling MR, et al
Sudden unexpected death in epilepsy during cenobamate clinical development.
Epilepsia. 2023 May 23. doi: 10.1111/epi.17662.
PubMed Abstract available

BERTEOTTI C, Calvello C, Liguori C
The role of the orexin system in the bidirectional relation between sleep and epilepsy: new chances for patients with epilepsy by the antagonism to orexin receptors?
Epilepsia. 2023 May 22. doi: 10.1111/epi.17661.
PubMed Abstract available

SMITH ML, Puka K, Speechley KN, Ferro MA, et al
A longitudinal cohort study of mediators of health-related quality of life after pediatric epilepsy surgery or medical treatment.
Epilepsia. 2023 May 22. doi: 10.1111/epi.17660.
PubMed Abstract available

DOGRA D, Meza-Santoscoy PL, Gavrilovici C, Rehak R, et al
kcna1a mutant zebrafish model episodic ataxia type 1 (EA1) with epilepsy and respond to first-line therapy carbamazepine.
Epilepsia. 2023 May 20. doi: 10.1111/epi.17659.
PubMed Abstract available

STRITZELBERGER J, Gesmann A, Fuhrmann I, Brandner S, et al
Time dependent risk factors for epileptic seizures in glioblastoma patients: A retrospective analysis of 520 cases.
Epilepsia. 2023 May 18. doi: 10.1111/epi.17658.
PubMed Abstract available

PAOLO A, Francesca R, Ilaria M, Chiara V, et al
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "precision medicine" approach with fluoxetine.
Epilepsia. 2023 May 18. doi: 10.1111/epi.17656.
PubMed Abstract available

DELLAVALE D, Bonini F, Pizzo F, Makhalova J, et al
Spontaneous fast-ultradian dynamics of polymorphic interictal events in drug-resistant focal epilepsy.
Epilepsia. 2023 May 18. doi: 10.1111/epi.17655.
PubMed Abstract available

SPERLING MR
An interview with Riccardo De Feo, 2023 Epilepsia Prize Winner for Basic Science Research.
Epilepsia. 2023 May 17. doi: 10.1111/epi.17652.
PubMed

SPERLING MR
An interview with Brad Kamitaki, 2023 Epilepsia Prize Winner for Clinical Research.
Epilepsia. 2023 May 17. doi: 10.1111/epi.17653.
PubMed

VAN HUGTE EJH, Schubert D, Kasri NN
E/I balance in epilepsies and neurodevelopmental disorders: depolarizing GABA as a common mechanism.
Epilepsia. 2023 May 17. doi: 10.1111/epi.17651.
PubMed Abstract available

VAN WESTRHENEN A, Lazeron RHC, van Dijk JP, Leijten FSS, et al
Multimodal nocturnal seizure detection in children with epilepsy: a prospective, multicenter, long-term, in-home trial.
Epilepsia. 2023 May 17. doi: 10.1111/epi.17654.
PubMed Abstract available

FRAUSCHER B, Bartolomei F, Baud MO, Smith RJ, et al
Stimulation to probe, excite, and inhibit the epileptic brain.
Epilepsia. 2023 May 17. doi: 10.1111/epi.17640.
PubMed Abstract available

HINCKLEY CA, Zhu Z, Chu JH, Gubbels C, et al
Functional evaluation of epilepsy associated KCNT1 variants in multiple cellular systems reveals a predominant gain of function impact on channel properties.
Epilepsia. 2023 May 13. doi: 10.1111/epi.17648.
PubMed Abstract available

BAITE LD, Harvey EE, Fong MWK, McGonigal A, et al
Life Following Epilepsy Surgery: Building a Holistic Framework for Enhancing Post-Surgical Recovery and Rehabilitation.
Epilepsia. 2023 May 13. doi: 10.1111/epi.17646.
PubMed

KUNDU B, Charlebois CM, Anderson DN, Peters A, et al
Chronic intracranial recordings after resection for epilepsy reveal a 'running down' of epileptiform activity.
Epilepsia. 2023 May 10. doi: 10.1111/epi.17645.
PubMed Abstract available

SHAKHATREH L, Foster E, Siriratnam P, Neal A, et al
The impact of epilepsy surgery on quality of life: systematic review and meta-analysis.
Epilepsia. 2023 May 8. doi: 10.1111/epi.17644.
PubMed Abstract available

DECKER BM, Ellis CA, Schriver E, Fischbein K, et al
Characterizing the Treatment Gap in the U.S. Among Adult Patients with A New Diagnosis of Epilepsy.
Epilepsia. 2023 May 7. doi: 10.1111/epi.17641.
PubMed Abstract available

BARTH KJ, Sun J, Chiang CH, Qiao S, et al
Flexible, high-resolution cortical arrays with large coverage capture microscale high-frequency oscillations in patients with epilepsy.
Epilepsia. 2023 May 7. doi: 10.1111/epi.17642.
PubMed Abstract available

LUO P, Yang F, Li J, Niemeyer JE, et al
Excitatory-inhibitory mismatch shapes node recruitment in an epileptic network.
Epilepsia. 2023 May 3. doi: 10.1111/epi.17638.
PubMed Abstract available

ERIKSSON MH, Ripart M, Piper RJ, Moeller F, et al
Predicting seizure outcome after epilepsy surgery: do we need more complex models, larger samples, or better data?
Epilepsia. 2023 May 2. doi: 10.1111/epi.17637.
PubMed Abstract available

HAKEEM H, Alsfouk BAA, Kwan P, Brodie MJ, et al
Should substitution monotherapy or combination therapy be used after failure of the first antiseizure medication? Observations from a 30-year cohort study.
Epilepsia. 2023;64:1248-1258.
PubMed Abstract available

PANG EW, Lawn ND, Lee J, Dunne JW, et al
Mortality after a first-ever unprovoked seizure.
Epilepsia. 2023;64:1266-1277.
PubMed Abstract available

DIEDERICH S, Hemmeter U, Paulmann M, Mockenhaupt M, et al
Effects of dosage in new users of lamotrigine inducing epidermal necrolysis: Results of the German Registry of Severe Skin Reactions.
Epilepsia. 2023;64:1259-1265.
PubMed Abstract available

SNYDER KM, Forseth KJ, Donos C, Rollo PS, et al
Critical role of the ventral temporal lobe in naming.
Epilepsia. 2023;64:1200-1213.
PubMed Abstract available

REYNOLDS A, Vranic-Peters M, Lai A, Grayden DB, et al
Prognostic interictal electroencephalographic biomarkers and models to assess antiseizure medication efficacy for clinical practice: A scoping review.
Epilepsia. 2023;64:1125-1174.
PubMed Abstract available

WALGER L, Adler S, Wagstyl K, Henschel L, et al
Artificial intelligence for the detection of focal cortical dysplasia: Challenges in translating algorithms into clinical practice.
Epilepsia. 2023;64:1093-1112.
PubMed Abstract available

MATRICARDI S, Cestele S, Trivisano M, Kassabian B, et al
Gain of function SCN1A disease-causing variants: Expanding the phenotypic spectrum and functional studies guiding the choice of effective antiseizure medication.
Epilepsia. 2023;64:1331-1347.
PubMed Abstract available

April 2023

TRINKA E, Alsaadi T, Goji H, Maehara T, et al
Perampanel for the Treatment of People with Idiopathic Generalized Epilepsy in Clinical Practice.
Epilepsia. 2023 Apr 28. doi: 10.1111/epi.17631.
PubMed Abstract available

OLSON HE, Demarest S, Pestana-Knight E, Moosa AN, et al
Epileptic Spasms in CDKL5 Deficiency Disorder: Delayed Treatment and Poor Response to First-line Therapies.
Epilepsia. 2023 Apr 28. doi: 10.1111/epi.17630.
PubMed Abstract available

GARDELLA E, Michelucci R, Christensen HM, Fenger CD, et al
IRF2BPL as a novel causative gene for Progressive Myoclonus Epilepsy.
Epilepsia. 2023 Apr 28. doi: 10.1111/epi.17634.
PubMed Abstract available

XIE K, Gallagher RS, Shinohara RT, Xie SX, et al
Long term epilepsy outcome dynamics revealed by natural language processing of clinic notes.
Epilepsia. 2023 Apr 28. doi: 10.1111/epi.17633.
PubMed Abstract available

WISSEL BD, Greiner HM, Glauser TA, Mangano FT, et al
Automated, Machine Learning-Based Alerts Increase Epilepsy Surgery Referrals: A Randomized Controlled Trial.
Epilepsia. 2023 Apr 27. doi: 10.1111/epi.17629.
PubMed Abstract available

Correction to "genome-wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective study".
Epilepsia. 2023 Apr 27. doi: 10.1111/epi.17623.
PubMed

KNIGHT D, Mahida S, Kelly M, Poduri A, et al
Ezogabine impacts seizures and development in patients with KCNQ2 developmental and epileptic encephalopathy.
Epilepsia. 2023 Apr 25. doi: 10.1111/epi.17627.
PubMed Abstract available

VAN ROOTSELAAR AF, Cocozza S, Aronica E, Striano P, et al
Familial Adult Myoclonus Epilepsy: neuroimaging and neuropathological findings.
Epilepsia. 2023 Apr 25. doi: 10.1111/epi.17628.
PubMed Abstract available

HOHMANN L, Berger J, Kastell SU, Holtkamp M, et al
Domain-specific relationships of subjective and objective cognition in epilepsy.
Epilepsia. 2023 Apr 21. doi: 10.1111/epi.17624.
PubMed Abstract available

PEASE M, Elmer J, Shahabadi AZ, Mallela AN, et al
Predicting post-traumatic epilepsy using admission electroencephalography after severe traumatic brain injury.
Epilepsia. 2023 Apr 18. doi: 10.1111/epi.17622.
PubMed Abstract available

RAYNER G, Pieters J, Broomfield G, Eyres J, et al
The 'make or break' impact of family dynamics on psychological outcomes in focal epilepsy.
Epilepsia. 2023 Apr 18. doi: 10.1111/epi.17619.
PubMed Abstract available

CAMERON JM, Damiano JA, Grinton B, Carney PW, et al
Recognition and Epileptology of Protracted CLN3 Disease.
Epilepsia. 2023 Apr 11. doi: 10.1111/epi.17616.
PubMed Abstract available

HANIN A, Cespedes J, Pulluru Y, Gopaul M, et al
Review and standard operating procedures for collection of biospecimens and analysis of biomarkers in new onset refractory status epilepticus.
Epilepsia. 2023 Apr 11. doi: 10.1111/epi.17600.
PubMed Abstract available

DE STEFANO P, Baumann SM, Grzonka P, Sarbu OE, et al
Early timing of anesthesia in status epilepticus is associated with complete recovery - a seven-year retrospective two center study.
Epilepsia. 2023 Apr 9. doi: 10.1111/epi.17614.
PubMed Abstract available

SIMULA S, Garnier E, Contento M, Pizzo F, et al
Changes in Local and Network Brain Activity After Stereotactic Thermocoagulation in Patients with Drug-Resistant Epilepsy.
Epilepsia. 2023 Apr 9. doi: 10.1111/epi.17613.
PubMed Abstract available

ABBOUD MA, Kamen JL, Bass JS, Lin L, et al
Actigraphic Correlates of Neuropsychiatric Symptoms in Adults with Focal Epilepsy.
Epilepsia. 2023 Apr 8. doi: 10.1111/epi.17611.
PubMed Abstract available

CORBETT MA, Depienne C, Veneziano L, Klein KM, et al
Genetics of Familial Adult Myoclonus Epilepsy: From linkage studies to non-coding repeat expansions.
Epilepsia. 2023 Apr 6. doi: 10.1111/epi.17610.
PubMed Abstract available

STEFAN K, Mikel R, Schmidbauer Moritz L, Pelz Johann O, et al
Phenobarbital in Superrefractory Status Epilepticus (PIRATE): a retrospective, multicenter analysis.
Epilepsia. 2023 Apr 6. doi: 10.1111/epi.17608.
PubMed Abstract available

IRELLI EC, Cocchi E, Ramantani G, Morano A, et al
Sex-based electroclinical differences and prognostic factors in epilepsy with eyelid myoclonia.
Epilepsia. 2023 Apr 5. doi: 10.1111/epi.17609.
PubMed Abstract available

HAINC N, Alcaide-Leon P, Willinsky RA, Krings T, et al
Periventricular Nodular Heterotopia (PNH) associated with a "transmantle band sign" in epilepsy patients.
Epilepsia. 2023 Apr 4. doi: 10.1111/epi.17604.
PubMed Abstract available

MIGNON-RAVIX C, Riccardi F, Daquin G, Cacciagli P, et al
NAPB and developmental and epileptic encephalopathy: description of the electro-clinical profile associated to a novel pathogenic variant.
Epilepsia. 2023 Apr 4. doi: 10.1111/epi.17603.
PubMed Abstract available

GOPAUL MT, Hanin A, Cespedes J, Pulluru Y, et al
The Seasonality of New-Onset Refractory Status Epilepticus (NORSE).
Epilepsia. 2023 Apr 4. doi: 10.1111/epi.17606.
PubMed Abstract available

XIAO L, Zhou M, Tang Y, Hu S, et al
(18) F-SynVesT-1 positron emission tomography in a hypothalamic hamartoma with abnormal uptake.
Epilepsia. 2023;64:e43-e47.
PubMed Abstract available

MAKIELLO P, Feng T, Dunwoody B, Steckler F, et al
Comorbidities and predictors of health-related quality of life in Dravet syndrome: A 10-year, prospective follow-up study.
Epilepsia. 2023;64:1012-1020.
PubMed Abstract available

GASCOIGNE SJ, Waldmann L, Schroeder GM, Panagiotopoulou M, et al
A library of quantitative markers of seizure severity.
Epilepsia. 2023;64:1074-1086.
PubMed Abstract available

DI VITO L, Mazzoni S, Belotti LMB, Poluzzi E, et al
Impact of regulatory restrictions on the use of valproic acid in women of childbearing age: An Italian study.
Epilepsia. 2023;64:910-918.
PubMed Abstract available

FAINGOLD CL, Feng HJ
A unified hypothesis of SUDEP: Seizure-induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and other restorative respiratory response mechanisms mediated by the action of serotonin on the per
Epilepsia. 2023;64:779-796.
PubMed Abstract available

FAIRCLOUGH S, Goodden J, Chumas P, Mathew R, et al
Levetiracetam as a first-line antiseizure medication in WHO grade 2 glioma: Time to seizure freedom and rates of treatment failure.
Epilepsia. 2023;64:857-865.
PubMed Abstract available

SPINELLI L, Baroumand AG, Vulliemoz S, Momjian S, et al
Semiautomatic interictal electric source localization based on long-term electroencephalographic monitoring: A prospective study.
Epilepsia. 2023;64:951-961.
PubMed Abstract available

March 2023

WEISS SA
Can biomarkers of the epileptogenic zone be characterized in patients rendered seizure free alone?
Epilepsia. 2023 Mar 30. doi: 10.1111/epi.17599.
PubMed

GIRALDEZ BG, Serratosa JM, Striano S, Ikeda A, et al
Familial Adult Myoclonus Epilepsy: clinical findings, disease course and comorbidities.
Epilepsia. 2023 Mar 30. doi: 10.1111/epi.17595.
PubMed Abstract available

TRAVNICEK V, Klimes P, Cimbalnik J, Frauscher B, et al
Response: Can biomarkers of the epileptogenic zone be characterized in patients rendered seizure free alone?
Epilepsia. 2023 Mar 30. doi: 10.1111/epi.17597.
PubMed

ELKHATEEB N, Olivieri G, Siri B, Boyd S, et al
Natural history of epilepsy in argininosuccinic aciduria provides new insights into pathophysiology: a retrospective international study.
Epilepsia. 2023 Mar 30. doi: 10.1111/epi.17596.
PubMed Abstract available

CHO J, Kim H, Chae JH, Kim KJ, et al
Outcomes of the Second Withdrawal of Anti-Seizure Medication in Patients with Pediatric Onset-Epilepsy.
Epilepsia. 2023 Mar 28. doi: 10.1111/epi.17594.
PubMed Abstract available

SCHRAEGLE WA, Slomowitz RF, Gundlach C, Hsu DA, et al
Disadvantage and Neurocognitive Comorbidities in Childhood Idiopathic Epilepsies.
Epilepsia. 2023 Mar 25. doi: 10.1111/epi.17581.
PubMed Abstract available

TOKATLY LATZER I, Bertoldi M, DiBacco ML, Arning E, et al
The Presence and Severity of Epilepsy Coincide with Reduced GABA and Cortical Excitatory Markers in SSADH Deficiency.
Epilepsia. 2023 Mar 24. doi: 10.1111/epi.17592.
PubMed Abstract available

GIRARDIN ML, Flamand T, Roignot O, Abi Warde MT, et al
Treatment of new onset refractory status epilepticus/febrile infection-related epilepsy syndrome with tocilizumab in a child and a young adult.
Epilepsia. 2023 Mar 24. doi: 10.1111/epi.17591.
PubMed Abstract available

COPPOLA A, Dubbioso R, Cuccurullo C, Licchetta L, et al
Current treatment options for Familial Adult Myoclonus Epilepsy.
Epilepsia. 2023 Mar 22. doi: 10.1111/epi.17590.
PubMed Abstract available

FERNANDES M, Cardall A, Jing J, Ge W, et al
Identification of patients with epilepsy using automated electronic health records phenotyping.
Epilepsia. 2023 Mar 19. doi: 10.1111/epi.17589.
PubMed Abstract available

HERZOG AG, Carrazana E, Rabinowicz AL
A Comparison of Statistical versus Clinical Classifiers of Seizure Clustering in Women with Catamenial and Non-Catamenial Epilepsy.
Epilepsia. 2023 Mar 17. doi: 10.1111/epi.17588.
PubMed Abstract available

LIU X, Li Y, Li X, Chen S, et al
Scalp Ripple Rates for Rapid Epilepsy Differentiation and Seizure Activity Assessment: Applicability and Influential Factors.
Epilepsia. 2023 Mar 16. doi: 10.1111/epi.17587.
PubMed Abstract available

BECKER LL, Horn D, Boschann F, Van Hoeymissen E, et al
Primidone improves symptoms in TRPM3-linked developmental and epileptic encephalopathy with spike-and-wave activation in sleep.
Epilepsia. 2023 Mar 16. doi: 10.1111/epi.17586.
PubMed Abstract available

KVERNELAND M, Nakken KO, Hofoss D, Skogan AH, et al
Health-related quality of life in adults with drug-resistant focal epilepsy treated with modified Atkins diet in a randomized clinical trial.
Epilepsia. 2023 Mar 15. doi: 10.1111/epi.17585.
PubMed Abstract available

DEZSI G, Ozturk E, Harris G, Paul C, et al
Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones.
Epilepsia. 2023 Mar 14. doi: 10.1111/epi.17584.
PubMed Abstract available

RAMANTANI G, Westover B, Gliske S, Sarnthein J, et al
Passive and active markers of cortical excitability in epilepsy.
Epilepsia. 2023 Mar 10. doi: 10.1111/epi.17578.
PubMed Abstract available

BERL MM, Koop JI, Ailion A, Bearden DJ, et al
Leveraging Expertise and Optimizing Clinical Research: Initial Success of a Pediatric Epilepsy Surgery Collaborative.
Epilepsia. 2023 Mar 10. doi: 10.1111/epi.17579.
PubMed Abstract available

LI H, Liu X, Wang R, Lu A, et al
Blood-brain barrier damage and new-onset refractory status epilepticus: an exploratory study using dynamic contrast-enhanced MRI.
Epilepsia. 2023 Mar 9. doi: 10.1111/epi.17576.
PubMed Abstract available

FEYS O, Goldman S, Lolli V, Depondt C, et al
Diagnostic and therapeutic approaches in refractory insular epilepsy.
Epilepsia. 2023 Mar 4. doi: 10.1111/epi.17571.
PubMed Abstract available

KERR WT, Chen H, Figuera Losada M, Cheng C, et al
Reasons for ineligibility for clinical trials of patients with medication resistant epilepsy.
Epilepsia. 2023 Mar 4. doi: 10.1111/epi.17568.
PubMed Abstract available

LAFOURCADE CA, Sparks FT, Bordey A, Wyneken U, et al
Cannabinoid regulation of neurons in the dentate gyrus during epileptogenesis. Role of CB1R-associated proteins and downstream pathways.
Epilepsia. 2023 Mar 4. doi: 10.1111/epi.17569.
PubMed Abstract available

BOSSELMANN CM, Leu C, Lal D
Are AI language models such as ChatGPT ready to improve the care of individuals with epilepsy?
Epilepsia. 2023 Mar 3. doi: 10.1111/epi.17570.
PubMed

COSTA AM, Gol M, Lucchi C, Biagini G, et al
Antiepileptogenic effects of trilostane in the kainic acid model of temporal lobe epilepsy.
Epilepsia. 2023 Mar 2. doi: 10.1111/epi.17561.
PubMed Abstract available

BOU ASSI E, Schindler K, de Bezenac C, Denison T, et al
From Basic Sciences and Engineering to Epileptology: A Translational Approach.
Epilepsia. 2023 Mar 2. doi: 10.1111/epi.17566.
PubMed Abstract available

PRUCKNER P, Nenning KH, Fischmeister FPS, Yildirim MS, et al
Visual outcomes after anterior temporal lobectomy and transsylvian selective amygdalohippocampectomy: A quantitative comparison of clinical and diffusion data.
Epilepsia. 2023;64:705-717.
PubMed Abstract available

February 2023

LUCAS A, Cornblath EJ, Sinha N, Hadar P, et al
Resting State Functional Connectivity Demonstrates Increased Segregation in Bilateral Temporal Lobe Epilepsy.
Epilepsia. 2023 Feb 28. doi: 10.1111/epi.17565.
PubMed Abstract available

KLEIN P, Krauss GL, Steinhoff BJ, Devinsky O, et al
Failure to use new breakthrough treatments for epilepsy.
Epilepsia. 2023 Feb 28. doi: 10.1111/epi.17564.
PubMed Abstract available

SCHEFFER IE
The fascinating phenotypic spectrum of SCN1A gain-of-function epilepsies.
Epilepsia. 2023 Feb 28. doi: 10.1111/epi.17562.
PubMed

CHEN JS, Lamoureux AA, Shlobin NA, Elkaim LM, et al
Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Drug-Resistant Epilepsy: A Systematic Review and Individual Participant Data Meta-Analysis.
Epilepsia. 2023 Feb 23. doi: 10.1111/epi.17560.
PubMed Abstract available

GHOSN NJ, Xie K, Pattnaik AR, Gugger JJ, et al
A pharmacokinetic model of anti-seizure medication load to guide care in the Epilepsy Monitoring Unit.
Epilepsia. 2023 Feb 23. doi: 10.1111/epi.17558.
PubMed Abstract available

COSTA C, Oliver KL, Calvello C, Cameron JM, et al
IRF2BPL: A new genotype for progressive myoclonus epilepsies.
Epilepsia. 2023 Feb 21. doi: 10.1111/epi.17557.
PubMed Abstract available

WARSI NM, Wong SM, Gorodetsky C, Suresh H, et al
Which is more deleterious to cognitive performance? Interictal epileptiform discharges vs. anti-seizure medication.
Epilepsia. 2023 Feb 21. doi: 10.1111/epi.17556.
PubMed Abstract available

OLIVER KL, Scheffer IE, Bennett MF, Grinton BE, et al
Genes4Epilepsy: an epilepsy gene resource.
Epilepsia. 2023 Feb 21. doi: 10.1111/epi.17547.
PubMed Abstract available

STEVELINK R, Koeleman BPC, Sisodiya SM
Distinct genetic basis of common epilepsies and structural MRI measures.
Epilepsia. 2023 Feb 17. doi: 10.1111/epi.17529.
PubMed Abstract available

DUMA GM, Danieli A, Mento G, Vitale V, et al
Altered spreading of neuronal avalanches in temporal lobe epilepsy relates to cognitive performance: a resting-state hdEEG study.
Epilepsia. 2023 Feb 17. doi: 10.1111/epi.17551.
PubMed Abstract available

MILIOR G, Morin-Brureau M, Pallud J, Miles R, et al
Animal models and human tissue compared to better understand and treat the epilepsies.
Epilepsia. 2023 Feb 17. doi: 10.1111/epi.17552.
PubMed Abstract available

DUBBIOSO R, Suppa A, Tijssen MAJ, Ikeda A, et al
Familial Adult Myoclonus Epilepsy: neurophysiological investigations.
Epilepsia. 2023 Feb 17. doi: 10.1111/epi.17553.
PubMed Abstract available

BURATTI S, Giacheri E, Palmieri A, Tibaldi J, et al
Ketamine as advanced second line treatment in benzodiazepine-refractory convulsive status epilepticus in children.
Epilepsia. 2023 Feb 15. doi: 10.1111/epi.17550.
PubMed Abstract available

PENA-CEBALLOS J, Moloney PB, Munteanu T, Doyle M, et al
Adjunctive cenobamate in highly active and ultra-refractory focal epilepsy: A 'real-world' retrospective study.
Epilepsia. 2023 Feb 15. doi: 10.1111/epi.17549.
PubMed Abstract available

COPPOLA A, Bilo L, Striano P
A solved puzzle: Familial Adult Myoclonus Epilepsy is a new expansion repeats disorder.
Epilepsia. 2023 Feb 13. doi: 10.1111/epi.17545.
PubMed

OLIVER KL, Trivisano M, Mandelstam SA, De Dominicis A, et al
WWOX Developmental and Epileptic Encephalopathy (WWOX-DEE): understanding the epileptology and the mortality risk.
Epilepsia. 2023 Feb 13. doi: 10.1111/epi.17542.
PubMed Abstract available

LEITNER DF, Siu Y, Korman A, Lin Z, et al
Metabolomic, Proteomic, and Transcriptomic Changes in Adults with Epilepsy on Modified Atkins Diet.
Epilepsia. 2023 Feb 12. doi: 10.1111/epi.17540.
PubMed Abstract available

SHARMA AA, Nenert R, Goodman A, Szaflarski JP, et al
Concordance between focal brain temperature elevations and focal edema in temporal lobe epilepsy.
Epilepsia. 2023 Feb 10. doi: 10.1111/epi.17538.
PubMed Abstract available

PELTOLA ME, Leitinger M, Halford JJ, Vinayan KP, et al
Routine and sleep EEG: Minimum recording standards of the International Federation of Clinical Neurophysiology and the International League Against Epilepsy.
Epilepsia. 2023 Feb 10. doi: 10.1111/epi.17448.
PubMed Abstract available

XIE K, Royer J, Lariviere S, Rodriguez-Cruces R, et al
Atypical intrinsic neural timescales in temporal lobe epilepsy.
Epilepsia. 2023 Feb 10. doi: 10.1111/epi.17541.
PubMed Abstract available

TRAVNICEK V, Klimes P, Cimbalnik J, Halamek J, et al
Relative Entropy is an easy-to-use invasive EEG Biomarker of the Epileptogenic Zone.
Epilepsia. 2023 Feb 10. doi: 10.1111/epi.17539.
PubMed Abstract available

MBIZVO GK, Bennett KH, Simpson CR, Duncan SE, et al
Using Critical Success Index or Gilbert Skill score as composite measures of positive predictive value and sensitivity in diagnostic accuracy studies: weather forecasting informing epilepsy research.
Epilepsia. 2023 Feb 8. doi: 10.1111/epi.17537.
PubMed

BAYKAN B, Franceschetti S, Canafoglia L, Cavalleri GL, et al
Differential diagnosis of familial adult myoclonic epilepsy.
Epilepsia. 2023 Feb 8. doi: 10.1111/epi.17536.
PubMed Abstract available

KRISHNA V, Mindel J, Sammartino F, Block C, et al
A Phase-1 Open-label Trial Evaluating Focused Ultrasound Unilateral Anterior Thalamotomy for Focal Onset Epilepsy.
Epilepsia. 2023 Feb 6. doi: 10.1111/epi.17535.
PubMed Abstract available

GRAIFMAN JL, Lippa NC, Mulhern MS, Bergner AL, et al
Clinical Utility of Exome Sequencing in a Pediatric Epilepsy Cohort.
Epilepsia. 2023 Feb 5. doi: 10.1111/epi.17534.
PubMed Abstract available

TAN M, Pearce N, Tobias A, Cook MJ, et al
The influence of comorbidity on mortality in patients with epilepsy and psychogenic non-epileptic seizures.
Epilepsia. 2023 Feb 5. doi: 10.1111/epi.17532.
PubMed Abstract available

NISSENKORN A, Kluger G, Schubert-Bast S, Bayat A, et al
Perampanel as Precision Therapy in Rare Genetic Epilepsies.
Epilepsia. 2023 Feb 2. doi: 10.1111/epi.17530.
PubMed Abstract available

CORNBLATH EJ, Lucas A, Armstrong C, Greenblatt AS, et al
Quantifying trial-by-trial variability during cortico-cortical evoked potential mapping of epileptogenic tissue.
Epilepsia. 2023 Feb 2. doi: 10.1111/epi.17528.
PubMed Abstract available

HANEEF Z, Skrehot HC
Neurostimulation in generalized epilepsy: A systematic review and meta-analysis.
Epilepsia. 2023 Feb 2. doi: 10.1111/epi.17524.
PubMed Abstract available

THARMARAJA T, Ho JSY, Rajakulendran S, Neligan A, et al
The Aetiology and Mortality of New Onset Refractory Status Epilepticus (NORSE) in Adults: A Systematic Review and Meta-analysis.
Epilepsia. 2023 Feb 2. doi: 10.1111/epi.17523.
PubMed Abstract available

GOLDENHOLZ DM, Westover MB
Flexible realistic simulation of seizure occurrence recapitulating statistical properties of seizure diaries.
Epilepsia. 2023;64:396-405.
PubMed Abstract available

ALCALA-ZERMENO JL, Starnes K, Gregg NM, Worrell G, et al
Responsive neurostimulation with low-frequency stimulation.
Epilepsia. 2023;64:e16-e22.
PubMed Abstract available

LYNCH M, Smith K, Riney K
Clinical seizure semiology is subtle and identification of seizures by parents is unreliable in infants with tuberous sclerosis complex.
Epilepsia. 2023;64:386-395.
PubMed Abstract available

FRENCH J, Biton V, Dave H, Detyniecki K, et al
A randomized phase 2b efficacy study in patients with seizure episodes with a predictable pattern using Staccato(R) alprazolam for rapid seizure termination.
Epilepsia. 2023;64:374-385.
PubMed Abstract available

January 2023

RUNDFELDT C, Klein P, Boison D, Rotenberg A, et al
Preclinical pharmacokinetics and tolerability of a novel meglumine-based parenteral solution of topiramate and topiramate combinations for treatment of status epilepticus.
Epilepsia. 2023 Jan 27. doi: 10.1111/epi.17520.
PubMed Abstract available

BERKOVIC SF, Striano P, Tsuji S
History of familial adult myoclonus epilepsy/benign adult familial myoclonic epilepsy around the world.
Epilepsia. 2023 Jan 27. doi: 10.1111/epi.17519.
PubMed Abstract available

CHEN C, Wang Y, Ye L, Xu J, et al
A region-specific modulation of sleep slow waves on interictal epilepsy markers in focal epilepsy.
Epilepsia. 2023 Jan 24. doi: 10.1111/epi.17518.
PubMed Abstract available

MACEA J, Bhagubai M, Broux V, De Vos M, et al
In-hospital and home-based long-term monitoring of focal epilepsy with a wearable electroencephalography device. Diagnostic yield and user experience.
Epilepsia. 2023 Jan 22. doi: 10.1111/epi.17517.
PubMed Abstract available

HUSEIN N, Langlois-Therien T, Rioux B, Josephson CB, et al
The medical and surgical treatment of epilepsy in older adults: a national survey.
Epilepsia. 2023 Jan 22. doi: 10.1111/epi.17516.
PubMed Abstract available

FISHER RS, McGinn RJ, Von Stein EL, Wu TQ, et al
Transcranial Direct Current Stimulation for Focal Status Epilepticus or Lateralized Periodic Discharges in Four Patients in a Critical Care Setting.
Epilepsia. 2023 Jan 20. doi: 10.1111/epi.17514.
PubMed Abstract available

CARROLL JH, Cross JH, Hickson M, Williams E, et al
A Core outcome set for childhood epilepsy treated with ketogenic diet therapy (CORE-KDT study): international parent and health professional consensus.
Epilepsia. 2023 Jan 18. doi: 10.1111/epi.17513.
PubMed Abstract available

BEATTY CW, Ahrens SM, Arredondo KH, Bagic AI, et al
Associations between testing and treatment pathways in lesional temporal or extratemporal epilepsy: A census survey of NAEC center directors.
Epilepsia. 2023 Jan 18. doi: 10.1111/epi.17512.
PubMed Abstract available

LOSCHER W
Is the antiparasitic drug ivermectin a suitable candidate for the treatment of epilepsy?
Epilepsia. 2023 Jan 16. doi: 10.1111/epi.17511.
PubMed Abstract available

TYE C, McEwen FS, Liang H, Woodhouse E, et al
Epilepsy severity mediates association between mutation type and ADHD symptoms in tuberous sclerosis complex.
Epilepsia. 2023 Jan 12. doi: 10.1111/epi.17507.
PubMed Abstract available

LASKIER V, Agyei-Kyeremateng KK, Eddy AE, Patel D, et al
Cost-effectiveness of cenobamate for focal seizures in people with drug-resistant epilepsy.
Epilepsia. 2023 Jan 10. doi: 10.1111/epi.17506.
PubMed Abstract available

DHARAN AL, Bowden SC, Peterson A, Lai A, et al
A cross-sectional investigation of cognition and epileptiform discharges in juvenile absence epilepsy.
Epilepsia. 2023 Jan 10. doi: 10.1111/epi.17505.
PubMed Abstract available

REYES A, Salinas L, Hermann BP, Baxendale S, et al
Establishing the cross-cultural applicability of a harmonized approach to cognitive diagnostics in epilepsy: Initial results of the IC-CoDE in a Spanish-speaking sample.
Epilepsia. 2023 Jan 10. doi: 10.1111/epi.17501.
PubMed Abstract available

BEGHI E, Giussani G, Costa C, DiFrancesco JC, et al
The epidemiology of epilepsy in older adults: A narrative review by the ILAE Task Force on Epilepsy in the Elderly.
Epilepsia. 2023 Jan 10. doi: 10.1111/epi.17494.
PubMed Abstract available

DEPIENNE C, van den Maagdenberg AMJM, Kuhnel T, Ishiura H, et al
Insights into familial adult myoclonus epilepsy pathogenesis: How the same repeat expansion in six unrelated genes may lead to cortical excitability.
Epilepsia. 2023 Jan 9. doi: 10.1111/epi.17504.
PubMed Abstract available

OWEN TW, Schroeder GM, Janiukstyte V, Hall GR, et al
MEG abnormalities and mechanisms of surgical failure in neocortical epilepsy.
Epilepsia. 2023 Jan 8. doi: 10.1111/epi.17503.
PubMed Abstract available

TAN M, Allemann SS, Qin XS, D'Souza WJ, et al
Adherence patterns in antiseizure medications (ASM) influencing risk of Sudden Unexplained Death in Epilepsy (SUDEP): a data linkage study using dispensed prescriptions.
Epilepsia. 2023 Jan 8. doi: 10.1111/epi.17502.
PubMed Abstract available

ISSA NP, Nunn KC, Wu S, Haider HA, et al
Putative roles for homeostatic plasticity in epileptogenesis.
Epilepsia. 2023 Jan 8. doi: 10.1111/epi.17500.
PubMed Abstract available

SANCHEZ FERNANDEZ I, Amengual-Gual M, Barcia Aguilar C, Romeu A, et al
Temporal trends in the cost and use of first-line treatments for infantile epileptic spasms syndrome.
Epilepsia. 2023 Jan 4. doi: 10.1111/epi.17498.
PubMed Abstract available

HOHMANN L, Bien CG, Holtkamp M, Grewe P, et al
How patients' psycho-social profile contributes to decision making in epilepsy surgery: A prospective study.
Epilepsia. 2023 Jan 4. doi: 10.1111/epi.17499.
PubMed Abstract available

LEITNER DF, Lin Z, Sawaged Z, Kanshin E, et al
Brain molecular mechanisms in Rasmussen encephalitis.
Epilepsia. 2023;64:218-230.
PubMed Abstract available

YOSSOFZAI O, Stone S, Madsen J, Moineddin R, et al
Seizure outcome of pediatric magnetic resonance-guided laser interstitial thermal therapy versus open surgery: A matched noninferiority cohort study.
Epilepsia. 2023;64:114-126.
PubMed Abstract available

FLANARY J, Daly S, Bakker C, Herman AB, et al
Reliability of visual review of intracranial electroencephalogram in identifying the seizure onset zone: A systematic review and implications for the accuracy of automated methods.
Epilepsia. 2023;64:6-16.
PubMed Abstract available

MCINTOSH AM, Wynd AW, Berkovic SF
Extended follow-up after anterior temporal lobectomy demonstrates seizure recurrence 20+ years postsurgery.
Epilepsia. 2023;64:92-102.
PubMed Abstract available

KNUPP KG, Scheffer IE, Ceulemans B, Sullivan J, et al
Fenfluramine provides clinically meaningful reduction in frequency of drop seizures in patients with Lennox-Gastaut syndrome: Interim analysis of an open-label extension study.
Epilepsia. 2023;64:139-151.
PubMed Abstract available

December 2022

WADLE NE, Schwab C, Seifart C, von Podewils F, et al
Prospective, longitudinal, multicenter study on the provision of information regarding sudden unexpected death in epilepsy to adults with epilepsy.
Epilepsia. 2022 Dec 22. doi: 10.1111/epi.17481.
PubMed Abstract available

LOLK K, Lange T, Elwert F, Dreier JW, et al
Traumatic brain injury, stroke, and epilepsy; A mediation study in a Danish nationwide cohort.
Epilepsia. 2022 Dec 20. doi: 10.1111/epi.17497.
PubMed Abstract available

SZAFLARSKI JP, Devinsky O, Lopez M, Park YD, et al
Long-term efficacy and safety of cannabidiol in patients with treatment-resistant epilepsies: 4-year results from the expanded access program.
Epilepsia. 2022 Dec 20. doi: 10.1111/epi.17496.
PubMed Abstract available

MACDONALD-LAURS E, Warren AEL, Lee WS, Yang JY, et al
Intrinsic and secondary epileptogenicity in focal cortical dysplasia type II.
Epilepsia. 2022 Dec 17. doi: 10.1111/epi.17495.
PubMed Abstract available

XIAO F, Caciagli L, Wandschneider B, Fleury M, et al
Verbal fluency fMRI detects anti-seizure effects and affective side effects of perampanel in people with focal epilepsy.
Epilepsia. 2022 Dec 16. doi: 10.1111/epi.17493.
PubMed Abstract available

CROW AJD, Thomas A, Rao Y, Beloor-Suresh A, et al
Task-based functional magnetic resonance imaging prediction of postsurgical cognitive outcomes in temporal lobe epilepsy: A systematic review, meta-analysis, and new data.
Epilepsia. 2022 Dec 15. doi: 10.1111/epi.17475.
PubMed Abstract available

WALTHER K, Kriwy P, Stritzelberger J, Graf W, et al
Attitudes towards persons with epilepsy as friends. Results of a factorial survey.
Epilepsia. 2022 Dec 15. doi: 10.1111/epi.17491.
PubMed Abstract available

MERITAM LARSEN P, Wustenhagen S, Terney D, Gardella E, et al
Duration of epileptic seizure types: A data-driven approach.
Epilepsia. 2022 Dec 15. doi: 10.1111/epi.17492.
PubMed Abstract available

TABAEE DAMAVANDI P, Storti B, Fabin N, Bianchi E, et al
Epilepsy in Cerebral Amyloid Angiopathy: an observational retrospective study of a large population.
Epilepsia. 2022 Dec 14. doi: 10.1111/epi.17489.
PubMed Abstract available

SU TY, Tang Y, Choi JY, Hu S, et al
Evaluating Whole-brain Tissue Property Changes in MRI-negative Pharmacoresistant Focal Epilepsies using MR Fingerprinting.
Epilepsia. 2022 Dec 12. doi: 10.1111/epi.17488.
PubMed Abstract available

MORGAN J, Moreno O, Alves M, Baz Z, et al
Increased uptake of the P2X7 receptor radiotracer (18) F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.
Epilepsia. 2022 Dec 12. doi: 10.1111/epi.17484.
PubMed Abstract available

QU S, Jackson LG, Zhou C, Shen D, et al
Heterozygous GABA(A) receptor beta3 subunit N110D knock-in mice have epileptic spasms.
Epilepsia. 2022 Dec 10. doi: 10.1111/epi.17470.
PubMed Abstract available

CONRAD EC, Revell AY, Greenblatt AS, Gallagher RS, et al
Spike patterns surrounding sleep and seizures localize the seizure onset zone in focal epilepsy.
Epilepsia. 2022 Dec 9. doi: 10.1111/epi.17482.
PubMed Abstract available

KEE D, Jette N, Blank LJ, Kummer BR, et al
Latent class analysis of eHealth behaviors among adults with epilepsy.
Epilepsia. 2022 Dec 9. doi: 10.1111/epi.17483.
PubMed Abstract available

BUDHRAM A, Burneo JG
Acute symptomatic seizures, epilepsy, and autoimmune encephalitis: Clarifying terminology in neural antibody-associated disease.
Epilepsia. 2022 Dec 5. doi: 10.1111/epi.17478.
PubMed

SHARMA S, Whitney R, Kossoff EH, RamachandranNair R, et al
Does the ketogenic ratio matter when using ketogenic diet therapy in pediatric epilepsy?
Epilepsia. 2022 Dec 5. doi: 10.1111/epi.17476.
PubMed Abstract available

HOPPE C, Beeres K, Witt JA, Sassen R, et al
Clinical adult outcome 11-30 years after pediatric epilepsy surgery: complications and other surgical adverse events, seizure control, and cure of epilepsy.
Epilepsia. 2022 Dec 5. doi: 10.1111/epi.17477.
PubMed Abstract available

YEW ANJ, Schraagen M, Otte WM, van Diessen E, et al
Transforming epilepsy research: a systematic review on natural language processing applications.
Epilepsia. 2022 Dec 3. doi: 10.1111/epi.17474.
PubMed Abstract available

CASTRO-VILLABLANCA F, Moeller F, Pujar S, D'Arco F, et al
Seizure outcome determinants in children after surgery for single unilateral lesions on magnetic resonance imaging: Role of preoperative ictal and interictal electroencephalography.
Epilepsia. 2022;63:3168-3179.
PubMed Abstract available

METCALF CS, Gagangras S, Bulaj G, White HS, et al
Synergistic effects of the galanin analog 810-2 with the antiseizure medication levetiracetam in rodent seizure models.
Epilepsia. 2022;63:3090-3099.
PubMed Abstract available

MAKRIDIS KL, Friedo AL, Kellinghaus C, Losch FP, et al
Successful treatment of adult Dravet syndrome patients with cenobamate.
Epilepsia. 2022;63:e164-e171.
PubMed Abstract available

DALIC LJ, Warren AEL, Spiegel C, Thevathasan W, et al
Paroxysmal fast activity is a biomarker of treatment response in deep brain stimulation for Lennox-Gastaut syndrome.
Epilepsia. 2022;63:3134-3147.
PubMed Abstract available

November 2022

HYDER SK, Ghosh A, Forcelli PA
Optogenetic activation of the superior colliculus attenuates spontaneous seizures in the pilocarpine model of temporal lobe epilepsy.
Epilepsia. 2022 Nov 30. doi: 10.1111/epi.17469.
PubMed Abstract available

GOEL K, Pek V, Shlobin NA, Chen JS, et al
Clinical Utility of Intraoperative Electrocorticography for Epilepsy Surgery: A Systematic Review and Meta-Analysis.
Epilepsia. 2022 Nov 20. doi: 10.1111/epi.17472.
PubMed Abstract available

VAN DER MEER PB, Maschio M, Dirven L, Taphoorn MJB, et al
First-line levetiracetam versus enzyme-inducing antiseizure medication in glioma patients with epilepsy.
Epilepsia. 2022 Nov 15. doi: 10.1111/epi.17464.
PubMed Abstract available

SONE D, Galovic M, Myers J, Leonhardt G, et al
Contribution of the mu-opioid receptor system to affective disorders in temporal lobe epilepsy: a bidirectional relationship?
Epilepsia. 2022 Nov 15. doi: 10.1111/epi.17463.
PubMed Abstract available

CHIANG S, Moss R, Stern JM, Hughes I, et al
Development of a core outcome set for quality of life for adults with drug-resistant epilepsy: A multi-stakeholder Delphi consensus study.
Epilepsia. 2022 Nov 8. doi: 10.1111/epi.17461.
PubMed Abstract available

LISGARAS CP, Scharfman HE
High Frequency Oscillations (250-500Hz) in Animal Models of Alzheimer's Disease and Two Animal Models of Epilepsy.
Epilepsia. 2022 Nov 8. doi: 10.1111/epi.17462.
PubMed Abstract available

KEREZOUDIS P, Worrell G, Van Gompel JJ
Letter to the Editor regarding "Management of epilepsy in older adults: A critical review by the ILAE Task Force on Epilepsy in the elderly".
Epilepsia. 2022 Nov 3. doi: 10.1111/epi.17456.
PubMed

SALPIETRO V, Galassi-Deforie V, Efthymiou S, O'Connor E, et al
De novo KCNA6 variants with attenuated KV 1.6 channel deactivation in patients with epilepsy.
Epilepsia. 2022 Nov 1. doi: 10.1111/epi.17455.
PubMed Abstract available

SHEN S, Dong Z, Sander JW, Zhou D, et al
Somatic symptom and related disorder in a large cohort of people with epilepsy: a cohort study.
Epilepsia. 2022 Nov 1. doi: 10.1111/epi.17453.
PubMed Abstract available

AHRENS SM, Arredondo KH, Bagic AI, Bai S, et al
Epilepsy center characteristics and geographic region influence presurgical testing in the United States.
Epilepsia. 2022 Nov 1. doi: 10.1111/epi.17452.
PubMed Abstract available

BERMAN E, Kohn E, Berkovitch M, Kovo M, et al
Lacosamide effects on placental carriers of essential compounds in comparison with valproate: Studies in perfused human placentas.
Epilepsia. 2022;63:2949-2957.
PubMed Abstract available

MENSAH JA, Johnson K, Reilly CA, Wilcox KS, et al
Evaluating the efficacy of prototype antiseizure drugs using a preclinical pharmacokinetic approach.
Epilepsia. 2022;63:2937-2948.
PubMed Abstract available

GATAULLINA S, Galvani G, Touchet S, Nous C, et al
GluN2C selective inhibition is a target to develop new antiepileptic compounds.
Epilepsia. 2022;63:2911-2924.
PubMed Abstract available

BIALER M, Johannessen SI, Koepp MJ, Levy RH, et al
Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI): I. Drugs in preclinical and early clinical development.
Epilepsia. 2022;63:2865-2882.
PubMed Abstract available

October 2022

Corrigendum to "Brain network excitatory/inhibitory imbalance is a biomarker for drug-naive Rolandic epilepsy: A radiomics strategy". [Epilepsia 2021, 62 (10): 2426-2438].
Epilepsia. 2022 Oct 29. doi: 10.1111/epi.17443.
PubMed

CERULLI IRELLI E, Cocchi E, Ramantani G, Riva A, et al
The spectrum of epilepsy with eyelid myoclonia: delineation of disease subtypes from a large multicenter study.
Epilepsia. 2022 Oct 28. doi: 10.1111/epi.17450.
PubMed Abstract available

YANG T, Roberts C, Winton-Brown T, Lloyd M, et al
Childhood trauma in patients with epileptic versus non-epileptic seizures.
Epilepsia. 2022 Oct 27. doi: 10.1111/epi.17449.
PubMed Abstract available

BLEAKLEY LE, McKenzie CE, Reid CA
Efficacy of anti-seizure medication in a mouse model of HCN1 developmental and epileptic encephalopathy.
Epilepsia. 2022 Oct 27. doi: 10.1111/epi.17447.
PubMed Abstract available

CLATOT J, Parthasarathy S, Cohen S, McKee J, et al
SCN1A gain-of-function mutation causing an early-onset epileptic encephalopathy.
Epilepsia. 2022 Oct 26. doi: 10.1111/epi.17444.
PubMed Abstract available

HSIEH JK, Pucci FG, Sundar SJ, Kondylis E, et al
Beyond Seizure-Freedom: Dissecting Long-Term Seizure Control after Surgical Resection for Drug Resistant Epilepsy.
Epilepsia. 2022 Oct 25. doi: 10.1111/epi.17445.
PubMed Abstract available

YUAN F, Damien C, Gaspard N
Prognostic Scores in Status Epilepticus: A Systematic Review and Meta-analysis.
Epilepsia. 2022 Oct 21. doi: 10.1111/epi.17442.
PubMed Abstract available

PICCENNA L, O'Dwyer R, Leppik I, Beghi E, et al
Management of epilepsy in older adults: A critical review by the ILAE Task Force on Epilepsy in the elderly.
Epilepsia. 2022 Oct 20. doi: 10.1111/epi.17426.
PubMed Abstract available

DOUBLET T, Ghestem A, Bernard C
Deficit in observational learning in experimental epilepsy.
Epilepsia. 2022 Oct 5. doi: 10.1111/epi.17421.
PubMed Abstract available

LOSCHER W, Stafstrom CE
Epilepsy and its neurobehavioral comorbidities: insights gained from animal models.
Epilepsia. 2022 Oct 5. doi: 10.1111/epi.17433.
PubMed Abstract available

TAWEEL B, Marson AG, Mirza N
A systems medicine strategy to predict the efficacy of drugs for monogenic epilepsies.
Epilepsia. 2022 Oct 5. doi: 10.1111/epi.17429.
PubMed Abstract available

WANG G, Song Y, Su J, Fan Z, et al
Altered Cerebellar-Motor Loop in Benign Adult Familial Myoclonic Epilepsy Type 1: The Structural Basis of Cortical Tremor.
Epilepsia. 2022 Oct 5. doi: 10.1111/epi.17430.
PubMed Abstract available

KIM MJ, Hwang B, Mampre D, Negoita S, et al
Ablation of Apparent Diffusion Coefficient Hyperintensity Clusters in Mesial Temporal Lobe Epilepsy Improves Seizure Outcomes after Laser Interstitial Thermal Therapy.
Epilepsia. 2022 Oct 5. doi: 10.1111/epi.17432.
PubMed Abstract available

MARCELLE M, You X, Fanto EJ, Sepeta LN, et al
Impact of development and recent-onset epilepsy on language dominance.
Epilepsia. 2022;63:2637-2649.
PubMed Abstract available

MYREN-SVELSTAD S, Jamali A, Ophus SS, D'gama PP, et al
Elevated photic response is followed by a rapid decay and depressed state in ictogenic networks.
Epilepsia. 2022;63:2543-2560.
PubMed Abstract available

MISRA SN, Sperling MR, Rao VR, Peters JM, et al
Significant improvements in SEIzure interVAL (time between seizure clusters) across time in patients treated with diazepam nasal spray as intermittent rescue therapy for seizure clusters.
Epilepsia. 2022;63:2684-2693.
PubMed Abstract available

STUDER M, Rossini L, Spreafico R, Pelliccia V, et al
Why are type II focal cortical dysplasias frequently located at the bottom of sulcus? A neurodevelopmental hypothesis.
Epilepsia. 2022;63:2716-2721.
PubMed

HILL SF, Ziobro JM, Jafar-Nejad P, Rigo F, et al
Genetic interaction between Scn8a and potassium channel genes Kcna1 and Kcnq2.
Epilepsia. 2022;63:e125-e131.
PubMed Abstract available

HAHN CD, Jiang Y, Villanueva V, Zolnowska M, et al
A phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox-Gastaut syndrome (ELEKTRA).
Epilepsia. 2022;63:2671-2683.
PubMed Abstract available

FRENCH JA, Cleary E, Dlugos D, Farfel G, et al
Considerations for determining the efficacy of new antiseizure medications in children age 1 month to younger than 2 years.
Epilepsia. 2022;63:2664-2670.
PubMed Abstract available

SVEINSSON O, Andersson T, Carlsson S, Tomson T, et al
Perinatal risk factors for SUDEP: A population-based case-control study.
Epilepsia. 2022;63:e119-e124.
PubMed Abstract available

MAILLARD PY, Baer S, Schaefer E, Desnous B, et al
Molecular and clinical descriptions of patients with GABAA receptor gene variants (GABRA1, GABRB2, GABRB3, GABRG2): A cohort study, review of literature, and genotype-phenotype correlation.
Epilepsia. 2022;63:2519-2533.
PubMed Abstract available

September 2022

LE JT, Ballester-Rosado CJ, Frost JD Jr, Swann JW, et al
Neurobehavioral Deficits and a Progressive Ictogenesis in the Tetrodotoxin Model of Epileptic Spasms.
Epilepsia. 2022 Sep 30. doi: 10.1111/epi.17428.
PubMed Abstract available

WANG ET, Chiang S, Cleboski S, Rao VR, et al
Seizure count forecasting to aid diagnostic testing in epilepsy.
Epilepsia. 2022 Sep 23. doi: 10.1111/epi.17415.
PubMed Abstract available

DIENEL GA, Gillinder L, McGonigal A, Borges K, et al
Potential new roles for glycogen in epilepsy.
Epilepsia. 2022 Sep 19. doi: 10.1111/epi.17412.
PubMed Abstract available

RHEIMS S, Sperling M, Ryvlin P
Drug-Resistant Epilepsy and Mortality-Why and when do neuromodulation and epilepsy surgery reduce overall mortality.
Epilepsia. 2022 Sep 17. doi: 10.1111/epi.17413.
PubMed Abstract available

CASTANO VG, Spotnitz M, Waldman GJ, Joiner EF, et al
Identification of patients with drug resistant epilepsy in electronic medical record data using the Observational Medical Outcomes Partnership Common Data Model.
Epilepsia. 2022 Sep 14. doi: 10.1111/epi.17409.
PubMed Abstract available

GESCHE J, Beier CP
Drug resistance in idiopathic generalized epilepsies- evidence and concepts.
Epilepsia. 2022 Sep 14. doi: 10.1111/epi.17410.
PubMed Abstract available

GORDON LG, Elliott TM, Bennett C, Hollway G, et al
Early cost-utility analysis of genetically-guided therapy for patients with drug-resistant epilepsy.
Epilepsia. 2022 Sep 9. doi: 10.1111/epi.17408.
PubMed Abstract available

PARK H, Heo J, Kim MJ, Lee JH, et al
The longitudinal effect of oxcarbazepine on thyroid function in children and adolescents with epilepsy.
Epilepsia. 2022 Sep 8. doi: 10.1111/epi.17407.
PubMed Abstract available

PENOVICH PE, Glauser T
Seizure clusters: Practical aspects and clinical strategies to care for patients in the community.
Epilepsia. 2022;63 Suppl 1:S3-S5.
PubMed

HAUT SR, Nabbout R
Recognizing seizure clusters in the community: The path to uniformity and individualization in nomenclature and definition.
Epilepsia. 2022;63 Suppl 1:S6-S13.
PubMed Abstract available

PATEL AD, Becker DA
Introduction to use of an acute seizure action plan for seizure clusters and guidance for implementation.
Epilepsia. 2022;63 Suppl 1:S25-S33.
PubMed Abstract available

GIDAL B, Detyniecki K
Rescue therapies for seizure clusters: Pharmacology and target of treatments.
Epilepsia. 2022;63 Suppl 1:S34-S44.
PubMed Abstract available

KAPUR J, Long L, Dixon-Salazar T
Consequences: Bench to home.
Epilepsia. 2022;63 Suppl 1:S14-S24.
PubMed Abstract available

FAUGHT E
Economic aspects of treating seizure clusters.
Epilepsia. 2022;63 Suppl 1:S45-S54.
PubMed Abstract available

WHELESS JW, Friedman D, Krauss GL, Rao VR, et al
Future opportunities for research in rescue treatments.
Epilepsia. 2022;63 Suppl 1:S55-S68.
PubMed Abstract available

CORNWALL CD, Dahl SM, Nguyen N, Roberg LE, et al
Association of ictal imaging changes in status epilepticus and neurological deterioration.
Epilepsia. 2022 Sep 1. doi: 10.1111/epi.17404.
PubMed Abstract available

14th European Epilepsy Congress Geneva, Switzerland | 9-13 July 2022 Satellite Symposia Abstracts.
Epilepsia. 2022;63 Suppl 2:1-3.
PubMed

14(th) European Epilepsy Congress Geneva, Switzerland & Online 9-13 July 2022.
Epilepsia. 2022;63 Suppl 2:4-272.
PubMed

HO VM, Dewar S, Salamon N, Fried I, et al
Strategic targeting of the temporal lobe with orthogonal placement of responsive neurostimulation leads.
Epilepsia. 2022;63:e112-e118.
PubMed Abstract available

DORE-BRABANT G, Laflamme G, Millette M, Osterman B, et al
Adrenal insufficiency among children treated with hormonal therapy for infantile spasms.
Epilepsia. 2022;63:2350-2358.
PubMed Abstract available

ILYAS A, Hoffman C, Vakilna Y, Chaliyeduth S, et al
Forecasting seizure clusters from chronic ambulatory electrocorticography.
Epilepsia. 2022;63:e106-e111.
PubMed Abstract available

BAUMGARTNER T, Pitsch J, Olaciregui-Dague K, Hoppe C, et al
Seizure underreporting in LGI1 and CASPR2 antibody encephalitis.
Epilepsia. 2022;63:e100-e105.
PubMed Abstract available

PATODIA S, Lim YM, Chung F, Stylianou I, et al
Cortical neuronal hypertrophy and mTOR pathway activation in CAN regions in SUDEP.
Epilepsia. 2022;63:2427-2438.
PubMed Abstract available

CAMARILLO-RODRIGUEZ L, Leenen I, Waldman Z, Serruya M, et al
Temporal lobe interictal spikes disrupt encoding and retrieval of verbal memory: A subregion analysis.
Epilepsia. 2022;63:2325-2337.
PubMed Abstract available

August 2022

WICKSTROM R, Taraschenko O, Dilena R, Payne ET, et al
International consensus recommendations for management of New Onset Refractory Status Epilepticus (NORSE) incl. Febrile Infection-Related Epilepsy Syndrome (FIRES): Statements and Supporting Evidence.
Epilepsia. 2022 Aug 23. doi: 10.1111/epi.17397.
PubMed Abstract available

MARIAJOSEPH FP, Chen Z, Sekhar P, Rewell SS, et al
Incidence and risk factors of post-traumatic epilepsy following pediatric traumatic brain injury: a systematic review and meta-analysis.
Epilepsia. 2022 Aug 23. doi: 10.1111/epi.17398.
PubMed Abstract available

AHN SJ, Oh J, Kim DY, Son H, et al
Effects of CYP2C19 genetic polymorphisms on the pharmacokinetics of lacosamide in Korean patients with epilepsy.
Epilepsia. 2022 Aug 21. doi: 10.1111/epi.17399.
PubMed Abstract available

LEITNER DF, Devore S, Laze J, Friedman D, et al
Serotonin receptor expression in hippocampus and temporal cortex of temporal lobe epilepsy patients by postictal generalized electroencephalographic suppression duration.
Epilepsia. 2022 Aug 21. doi: 10.1111/epi.17400.
PubMed Abstract available

STREHLOW V, Rieubland C, Gallati S, Kim S, et al
Compound-heterozygous GRIN2A null variants associated with severe developmental and epileptic encephalopathy.
Epilepsia. 2022 Aug 19. doi: 10.1111/epi.17394.
PubMed Abstract available

NEHLIG A
Epilepsia: Thank you from an outgoing editor.
Epilepsia. 2022 Aug 17. doi: 10.1111/epi.17393.
PubMed

WICKSTROM R, Taraschenko O, Dilena R, Payne ET, et al
International consensus recommendations for management of New Onset Refractory Status Epilepticus (NORSE) including Febrile Infection-Related Epilepsy Syndrome (FIRES): Summary and Clinical Tools.
Epilepsia. 2022 Aug 11. doi: 10.1111/epi.17391.
PubMed Abstract available

NAJM I, Lal D, Alonso Vanegas M, Cendes F, et al
The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission.
Epilepsia. 2022;63:1899-1919.
PubMed Abstract available

HUFTHY Y, Bharadwaj M, Gupta S, Hussain D, et al
Statins as antiepileptogenic drugs: Analyzing the evidence and identifying the most promising statin.
Epilepsia. 2022;63:1889-1898.
PubMed Abstract available

NAGANUR V, Sivathamboo S, Chen Z, Kusmakar S, et al
Automated seizure detection with noninvasive wearable devices: A systematic review and meta-analysis.
Epilepsia. 2022;63:1930-1941.
PubMed Abstract available

NOBLE AJ, Haddad S, Coleman N, Marson AG, et al
Worth the paper they are printed on? Findings from an independent evaluation of the understandability of patient information leaflets for antiseizure medications.
Epilepsia. 2022;63:2130-2143.
PubMed Abstract available

July 2022

MILLER KJ, Fine AL
Decision making in stereotactic epilepsy surgery.
Epilepsia. 2022 Jul 31. doi: 10.1111/epi.17381.
PubMed Abstract available

MUKAINO T, Uehara T, Yokohama J, Okadome T, et al
Atrophy of the hippocampal CA1 subfield relates to long-term forgetting in focal epilepsy.
Epilepsia. 2022 Jul 27. doi: 10.1111/epi.17378.
PubMed Abstract available

STRITZELBERGER J, Walther K, Olmes D, Gollwitzer S, et al
Antiseizure medication and perceived "fair" cost allocation: a factorial survey among neurologists, persons with epilepsy, their relatives and a control group.
Epilepsia. 2022 Jul 27. doi: 10.1111/epi.17375.
PubMed Abstract available

DHAHER R, Bronen RA, Spencer L, Colic L, et al
The Dorsal Bed Nucleus of the Stria Terminalis in Depressed and Non-Depressed Temporal Lobe Epilepsy Patients.
Epilepsia. 2022 Jul 26. doi: 10.1111/epi.17377.
PubMed Abstract available

BRIGO F, Turcato G, Lattanzi S, Orlandi N, et al
Machine-learning validation through decision-tree analysis of the Epidemiology-based Mortality Score in Status Epilepticus.
Epilepsia. 2022 Jul 23. doi: 10.1111/epi.17372.
PubMed Abstract available

HARRIS SA, George AG, Barrett KT, Scantlebury MH, et al
Febrile seizures lead to prolonged epileptiform activity and hyperoxia that when blocked prevents learning deficits.
Epilepsia. 2022 Jul 19. doi: 10.1111/epi.17371.
PubMed Abstract available

FLEURY M, Buck S, Binding LP, Caciagli L, et al
Episodic Memory Network Connectivity in Temporal Lobe Epilepsy.
Epilepsia. 2022 Jul 18. doi: 10.1111/epi.17370.
PubMed Abstract available

CHISOLM PF, Warner JD, Hale AT, Estevez-Ordonez D, et al
Quantifying and Reporting Outcomes in Pediatric Epilepsy Surgery: A Systematic Review.
Epilepsia. 2022 Jul 18. doi: 10.1111/epi.17369.
PubMed Abstract available

JEHI L, Jette N, Kwon CS, Josephson CB, et al
Timing of referral to evaluate for epilepsy surgery: Expert Consensus Recommendations from the Surgical Therapies Commission of the International League Against Epilepsy.
Epilepsia. 2022 Jul 17. doi: 10.1111/epi.17350.
PubMed Abstract available

PEDERSEN M, Abbott DF, Jackson GD
Wearable OPM-MEG: a changing landscape for epilepsy.
Epilepsia. 2022 Jul 16. doi: 10.1111/epi.17368.
PubMed Abstract available

WARSI NM, Wong SM, Suresh H, Arski ON, et al
Interictal discharges delay target-directed eye movements and impair attentional set-shifting in children with epilepsy.
Epilepsia. 2022 Jul 14. doi: 10.1111/epi.17365.
PubMed Abstract available

IKEMOTO S, von Ellenrieder N, Gotman J
EEG-fMRI of epileptiform discharges: non-invasive investigation of the whole brain.
Epilepsia. 2022 Jul 13. doi: 10.1111/epi.17364.
PubMed Abstract available

SINGH J, Ebersole JS, Brinkmann BH
From Theory to Practical Fundamentals of EEG Source Imaging in Localizing the Epileptogenic zone.
Epilepsia. 2022 Jul 11. doi: 10.1111/epi.17361.
PubMed Abstract available

ROMOLI M, Merli E, Galluzzo S, Muccioli L, et al
Hyper-perfusion Tmax mapping for non-convulsive status epilepticus in the acute setting: a pilot case-control study.
Epilepsia. 2022 Jul 6. doi: 10.1111/epi.17359.
PubMed Abstract available

AHRING PK, Liao VWY, Lin S, Absalom NL, et al
The de novo GABRA4 p.Thr300Ile variant found in a patient with early-onset intractable epilepsy and neurodevelopmental abnormalities displays gain-of-function traits.
Epilepsia. 2022 Jul 4. doi: 10.1111/epi.17358.
PubMed

ARSKI ON, Wong SM, Warsi NM, Pang E, et al
Epilepsy disrupts hippocampal phase precision and impairs working memory.
Epilepsia. 2022 Jul 2. doi: 10.1111/epi.17357.
PubMed Abstract available

MUCCIOLI L, Zenesini C, Taruffi L, Licchetta L, et al
Risk of hospitalization and death for COVID-19 in persons with epilepsy over a 20-month period: the EpiLink Bologna cohort, Italy.
Epilepsia. 2022 Jul 2. doi: 10.1111/epi.17356.
PubMed Abstract available

NEAL A, Bouet R, Lagarde S, Ostrowsky-Coste K, et al
Epileptic spasms are associated with increased SEEG derived functional connectivity in tuberous sclerosis complex.
Epilepsia. 2022 Jul 1. doi: 10.1111/epi.17353.
PubMed Abstract available

NEHLIG A, Sperling MR
The debate on the treatment of neonatal seizures: Introductory remarks.
Epilepsia. 2022;63:1862.
PubMed

KAILA K, Loscher W
Bumetanide for neonatal seizures: No light in the pharmacokinetic/dynamic tunnel.
Epilepsia. 2022;63:1868-1873.
PubMed Abstract available

STALEY KJ
Clarifications regarding bumetanide for neonatal seizures.
Epilepsia. 2022;63:1863-1867.
PubMed Abstract available

PRESSLER RM, Boylan GB
Translational neonatal seizure research-A reality check.
Epilepsia. 2022;63:1874-1879.
PubMed

AUVIN S
Finally, a controversy about neonatal seizure treatment.
Epilepsia. 2022;63:1880-1882.
PubMed

TERMAN SW, Wang C, Wang L, Braun KPJ, et al
Reappraisal of the Medical Research Council Antiepileptic Drug Withdrawal Study: Contamination-adjusted and dose-response re-analysis.
Epilepsia. 2022;63:1724-1735.
PubMed Abstract available

WIRRELL EC, Hood V, Knupp KG, Meskis MA, et al
International consensus on diagnosis and management of Dravet syndrome.
Epilepsia. 2022;63:1761-1777.
PubMed Abstract available

VARATHARAJAH Y, Joseph B, Brinkmann B, Morita-Sherman M, et al
Quantitative analysis of visually reviewed normal scalp EEG predicts seizure freedom following anterior temporal lobectomy.
Epilepsia. 2022;63:1630-1642.
PubMed Abstract available

HOOD V, Berg AT, Knupp KG, Koh S, et al
COVID-19 vaccine in patients with Dravet syndrome: Observations and real-world experiences.
Epilepsia. 2022;63:1778-1786.
PubMed Abstract available

CASCINO GD, Tarquinio D, Wheless JW, Hogan RE, et al
Lack of clinically relevant differences in safety and pharmacokinetics after second-dose administration of intranasal diazepam within 4 h for acute treatment of seizure clusters: A population analysis.
Epilepsia. 2022;63:1714-1723.
PubMed Abstract available

CHAITANYA G, Hampson JP, Toth E, Hupp NJ, et al
Limbic and paralimbic respiratory modulation: From inhibition to enhancement.
Epilepsia. 2022;63:1799-1811.
PubMed Abstract available

June 2022

GRACIE L, Rostami-Hochaghan D, Taweel B, Mirza N, et al
The Seizure-Associated Genes Across Species (SAGAS) database offers insights into epilepsy genes, pathways and treatments.
Epilepsia. 2022 Jun 29. doi: 10.1111/epi.17352.
PubMed Abstract available

PEDERSEN S, Kverneland M, Nakken KO, Rudi K, et al
Genome-wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective study.
Epilepsia. 2022 Jun 28. doi: 10.1111/epi.17351.
PubMed Abstract available

OTTMAN R, Wetmore JB, Camarillo IA, Rodriguez S, et al
Reproduction and Genetic Causal Attribution of Epilepsy.
Epilepsia. 2022 Jun 27. doi: 10.1111/epi.17349.
PubMed Abstract available

VAITKEVICIUS H, Ramsay RE, Swisher CB, Husain AM, et al
Intravenous Ganaxolone for the Treatment of Refractory Status Epilepticus: Results from an Open-Label, Dose-Finding, Phase 2 Trial.
Epilepsia. 2022 Jun 24. doi: 10.1111/epi.17343.
PubMed Abstract available

SAMIA P, Hassell J, Hudson J, Ahmed A, et al
Epilepsy research in Africa: A scoping review by the ILAE Pediatric Commission Research Advocacy Task Force.
Epilepsia. 2022 Jun 21. doi: 10.1111/epi.17321.
PubMed Abstract available

SAKOVICS A, Csukly G, Borbely C, Virag M, et al
Prolongation of cortical sleep spindles during hippocampal interictal epileptiform discharges in epilepsy patients.
Epilepsia. 2022 Jun 20. doi: 10.1111/epi.17337.
PubMed Abstract available

JETTE N, Kirkpatrick M, Lin K, Fernando SMS, et al
What is a clinical practice guideline? A roadmap to their development. Special report from the Guidelines Task Force of the International League Against Epilepsy.
Epilepsia. 2022 Jun 20. doi: 10.1111/epi.17312.
PubMed Abstract available

KNOWLES JK, Helbig I, Metcalf CS, Lubbers LS, et al
Precision medicine for genetic epilepsy on the horizon: recent advances, present challenges and suggestions for continued progress.
Epilepsia. 2022 Jun 18. doi: 10.1111/epi.17332.
PubMed Abstract available

URQUIA-OSORIO H, Pimentel-Silva LR, Rezende TJR, Almendares-Bonilla E, et al
Superficial and deep white matter diffusion abnormalities in focal epilepsies.
Epilepsia. 2022 Jun 16. doi: 10.1111/epi.17333.
PubMed Abstract available

YANG JC, Bullinger KL, Dickey AS, Karakis I, et al
Anterior Nucleus of the Thalamus Deep Brain Stimulation Versus Temporal Lobe Responsive Neurostimulation for Temporal Lobe Epilepsy.
Epilepsia. 2022 Jun 15. doi: 10.1111/epi.17331.
PubMed Abstract available

CHAU LOO KUNG G, Chiu A, Davey Z, Mouchawar N, et al
High-resolution hippocampal diffusion tensor imaging of mesial temporal sclerosis in refractory epilepsy.
Epilepsia. 2022 Jun 15. doi: 10.1111/epi.17330.
PubMed Abstract available

SIMPSON HD, Schulze-Bonhage A, Cascino GD, Fisher RS, et al
Practical considerations in epilepsy neurostimulation.
Epilepsia. 2022 Jun 14. doi: 10.1111/epi.17329.
PubMed Abstract available

APANTAKU GO, McDonald PJ, Aguiar M, Cabrera LY, et al
Clinician preferences for neurotechnologies in pediatric drug resistant epilepsy: a discrete choice experiment.
Epilepsia. 2022 Jun 14. doi: 10.1111/epi.17328.
PubMed Abstract available

LI R, Deng C, Wang X, Zou T, et al
Interictal dynamic network transitions in mesial temporal lobe epilepsy.
Epilepsia. 2022 Jun 14. doi: 10.1111/epi.17325.
PubMed Abstract available

COLE ER, Grogan DP, Laxpati NG, Fernandez A, et al
Evidence Supporting Deep Brain Stimulation of the Medial Septum in the Treatment of Temporal Lobe Epilepsy.
Epilepsia. 2022 Jun 14. doi: 10.1111/epi.17326.
PubMed Abstract available

NEMESURE MD, Streltzov N, Schommer LM, Lekkas D, et al
Predictive Modeling of Suicidal Ideation in Patients with Epilepsy.
Epilepsia. 2022 Jun 11. doi: 10.1111/epi.17324.
PubMed Abstract available

BEDROSIAN TA, Miller KE, Grischow OE, Schieffer KM, et al
Detection of brain somatic variation in epilepsy-associated developmental lesions.
Epilepsia. 2022 Jun 10. doi: 10.1111/epi.17323.
PubMed Abstract available

YOSSOFZAI O, Fallah A, Maniquis C, Wang S, et al
Development and Validation of Machine Learning Models for Prediction of Seizure Outcome After Pediatric Epilepsy Surgery.
Epilepsia. 2022 Jun 6. doi: 10.1111/epi.17320.
PubMed Abstract available

TANG Y, Su TY, Choi JY, Hu S, et al
Characterizing Thalamic and Basal Ganglia Nuclei in Medically Intractable Focal Epilepsy by MR Fingerprinting.
Epilepsia. 2022 Jun 4. doi: 10.1111/epi.17318.
PubMed Abstract available

STODBERG T, Tomson T, Anderlid BM, Andersson T, et al
Outcome at age 7 of epilepsy presenting in the first 2 years of life. A population-based study.
Epilepsia. 2022 Jun 2. doi: 10.1111/epi.17314.
PubMed Abstract available

LI EC, Zheng Y, Cai MT, Lai QL, et al
Seizures and epilepsy in multiple sclerosis, aquaporin 4 antibody-positive neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody-associated disease.
Epilepsia. 2022 Jun 2. doi: 10.1111/epi.17315.
PubMed Abstract available

LOPEZ SM, Aksman LM, Oxtoby NP, Vos SB, et al
Event-based modelling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data.
Epilepsia. 2022 Jun 2. doi: 10.1111/epi.17316.
PubMed Abstract available

HAKANSSON S, Zelano J
Big data analysis of ASM retention rates and expert ASM algorithm: A comparative study.
Epilepsia. 2022;63:1553-1562.
PubMed Abstract available

NISHI T, Metcalf CS, Fujimoto S, Hasegawa S, et al
Anticonvulsive properties of soticlestat, a novel cholesterol 24-hydroxylase inhibitor.
Epilepsia. 2022;63:1580-1590.
PubMed Abstract available

HINGRAY C, Ertan D, Reuber M, Lother AS, et al
Heterogeneity of patients with functional/dissociative seizures: Three multidimensional profiles.
Epilepsia. 2022;63:1500-1515.
PubMed Abstract available

PARK DK, Kim W, Thornburg OS, McBrian DK, et al
Convolutional neural network-aided tuber segmentation in tuberous sclerosis complex patients correlates with electroencephalogram.
Epilepsia. 2022;63:1530-1541.
PubMed Abstract available

May 2022

MALONEY EM, Corcoran P, Costello DJ, O'Reilly EJ, et al
Association between social deprivation and incidence of first seizures and epilepsy: a prospective population based cohort.
Epilepsia. 2022 May 25. doi: 10.1111/epi.17313.
PubMed Abstract available

MAKHALOVA J, Medina Villalon S, Wang H, Giusiano B, et al
Virtual Epileptic Patient brain modeling: relationships with seizure onset and surgical outcome.
Epilepsia. 2022 May 23. doi: 10.1111/epi.17310.
PubMed Abstract available

BAKULA DM, Junger KW, Guilfoyle SM, Mara CA, et al
Key Predictors of the Need for a Family-Focused Pediatric Epilepsy Adherence Intervention.
Epilepsia. 2022 May 21. doi: 10.1111/epi.17302.
PubMed Abstract available

SHIH YC, Chou CC, Peng SJ, Yu HY, et al
Clinical characteristics and long-term outcome of cerebral cavernous malformations-related epilepsy.
Epilepsia. 2022 May 20. doi: 10.1111/epi.17309.
PubMed Abstract available

FUKUMA K, Ikeda S, Tanaka T, Kamogawa N, et al
Clinical and imaging features of nonmotor onset seizure in poststroke epilepsy.
Epilepsia. 2022 May 20. doi: 10.1111/epi.17308.
PubMed Abstract available

HAMMER MF, Pan Y, Cumbay M, Pendziwiat M, et al
Whole exome sequencing and co-expression analysis identify an SCN1A variant that modifies pathogenicity in a family with Genetic Epilepsy and Febrile Seizures Plus (GEFS+).
Epilepsia. 2022 May 20. doi: 10.1111/epi.17296.
PubMed Abstract available

SCHULZE-BONHAGE A, Bruno E, Brandt A, Shek A, et al
Diagnostic yield and limitations of in-hospital documentation in patients with epilepsy.
Epilepsia. 2022 May 18. doi: 10.1111/epi.17307.
PubMed Abstract available

MOURA LMVR, Karakis I, Zack MM, Tian N, et al
Drivers of US Healthcare Spending for Persons with Seizures and/or Epilepsies, 2010-2018.
Epilepsia. 2022 May 17. doi: 10.1111/epi.17305.
PubMed Abstract available

THIO LL, Edgar L, Ali I, Farooque P, et al
Epilepsy Milestones 2.0 - An Updated Framework for Assessing Epilepsy Fellowships and Fellows.
Epilepsia. 2022 May 17. doi: 10.1111/epi.17306.
PubMed Abstract available

SONCIN LD, Faure S, McGonigal A, Horowitz T, et al
Correlation between FDG-PET brain hypometabolism and PTSD symptoms in temporal lobe epilepsy.
Epilepsia. 2022 May 15. doi: 10.1111/epi.17300.
PubMed Abstract available

CHARLEBOIS CM, Anderson DN, Johnson KA, Philip BJ, et al
Patient-specific structural connectivity informs outcomes of responsive neurostimulation for temporal lobe epilepsy.
Epilepsia. 2022 May 13. doi: 10.1111/epi.17298.
PubMed Abstract available

THONGSING A, Eizadkhah D, Fields C, Ballaban-Gil K, et al
Provoked seizures and status epilepticus in the pediatric population with COVID-19 disease.
Epilepsia. 2022 May 9. doi: 10.1111/epi.17293.
PubMed Abstract available

OHMORI I, Ouchida M, Shinohara M, Kobayashi K, et al
A novel animal model of combined generalized and focal epilepsy.
Epilepsia. 2022 May 9. doi: 10.1111/epi.17295.
PubMed Abstract available

TENG LY, Lee VW, Murugesu S, Lee JX, et al
The Glycemic Biomarkers in Children with Drug-Resistant Epilepsy on Various Types of Ketogenic Diet Therapies: A Cross-sectional study.
Epilepsia. 2022 May 8. doi: 10.1111/epi.17292.
PubMed Abstract available

VETKAS A, Fomenko A, Germann J, Sarica C, et al
Response: Letter to the Editor: Deep brain stimulation targets in epilepsy: Systematic review and meta-analysis of anterior and centromedian thalamic nuclei and hippocampus.
Epilepsia. 2022 May 5. doi: 10.1111/epi.17272.
PubMed

RINEY K, Bogacz A, Somerville E, Hirsch E, et al
International League Against Epilepsy classification and definition of epilepsy syndromes with onset at a variable age: position statement by the ILAE Task Force on Nosology and Definitions.
Epilepsia. 2022 May 3. doi: 10.1111/epi.17240.
PubMed Abstract available

SPECCHIO N, Wirrell EC, Scheffer IE, Nabbout R, et al
International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions.
Epilepsia. 2022 May 3. doi: 10.1111/epi.17241.
PubMed Abstract available

HIRSCH E, French J, Scheffer IE, Bogacz A, et al
ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions.
Epilepsia. 2022 May 3. doi: 10.1111/epi.17236.
PubMed Abstract available

WIRRELL EC, Nabbout R, Scheffer IE, Alsaadi T, et al
Methodology for classification and definition of epilepsy syndromes with list of syndromes: Report of the ILAE Task Force on Nosology and Definitions.
Epilepsia. 2022 May 3. doi: 10.1111/epi.17237.
PubMed Abstract available

ZUBERI SM, Wirrell E, Yozawitz E, Wilmshurst JM, et al
ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions.
Epilepsia. 2022 May 3. doi: 10.1111/epi.17239.
PubMed Abstract available

WIRRELL E, Tinuper P, Perucca E, Moshe SL, et al
Introduction to the epilepsy syndrome papers.
Epilepsia. 2022 May 3. doi: 10.1111/epi.17262.
PubMed

LATTANZI S, Ascoli M, Canafoglia L, Paola Canevini M, et al
Sustained seizure freedom with adjunctive brivaracetam in patients with focal onset seizures.
Epilepsia. 2022;63:e42-e50.
PubMed Abstract available

BIONDI A, Santoro V, Viana PF, Laiou P, et al
Noninvasive mobile EEG as a tool for seizure monitoring and management: A systematic review.
Epilepsia. 2022;63:1041-1063.
PubMed Abstract available

TARRADA A, Aron O, Vignal JP, Ertan D, et al
Anticipatory anxiety of seizures is associated with ictal emotional distress and amygdala onset seizures.
Epilepsia. 2022;63:1130-1140.
PubMed Abstract available

KILPATTU RAMANIHARAN A, Zhang MW, Selladurai G, Martin R, et al
Loss of hippocampal dentation in hippocampal sclerosis and its relationship to memory dysfunction.
Epilepsia. 2022;63:1104-1114.
PubMed Abstract available

CHOURASIA N, Yuskaitis CJ, Libenson MH, Bergin AM, et al
Infantile spasms: Assessing the diagnostic yield of an institutional guideline and the impact of etiology on long-term treatment response.
Epilepsia. 2022;63:1164-1176.
PubMed Abstract available

VAN WESTRHENEN A, Wijnen BFM, Thijs RD
Parental preferences for seizure detection devices: A discrete choice experiment.
Epilepsia. 2022;63:1152-1163.
PubMed Abstract available

RIBAN V, Heulard I, Reversat L, Si Hocine H, et al
Stiripentol inhibits spike-and-wave discharges in animal models of absence seizures: A new mechanism of action involving T-type calcium channels.
Epilepsia. 2022;63:1200-1210.
PubMed Abstract available

April 2022

AL-KRAIMEEN LM, Ababneh O, Yassin A
Letter to the Editor: "Deep brain stimulation targets in epilepsy: Systematic review and meta-analysis of anterior and centromedian thalamic nuclei and hippocampus".
Epilepsia. 2022 Apr 29. doi: 10.1111/epi.17270.
PubMed

LEAL-PARDINAS F, Truty R, McKnight DA, Johnson B, et al
Value of genetic testing for pediatric epilepsy: Driving earlier diagnosis of CLN2 Batten disease.
Epilepsia. 2022 Apr 26. doi: 10.1111/epi.17269.
PubMed Abstract available

DE FEO R, Manninen E, Chary K, Hamalainen E, et al
Hippocampal position and orientation as prognostic biomarkers for post-traumatic epileptogenesis - an experimental study in rat lateral fluid-percussion model.
Epilepsia. 2022 Apr 22. doi: 10.1111/epi.17264.
PubMed Abstract available

RAMOS-FRESNEDO A, Perez-Vega C, Domingo RA, Lee SJ, et al
Mesenchymal Stem Cell Therapy for Focal Epilepsy: A Systematic Review of Preclinical Models and Clinical Studies.
Epilepsia. 2022 Apr 22. doi: 10.1111/epi.17266.
PubMed Abstract available

STRIANO P, Auvin S, Collins A, Horvath R, et al
A randomized, double-blind trial of triheptanoin for drug-resistant epilepsy in glucose transporter I deficiency syndrome (Glut1DS).
Epilepsia. 2022 Apr 20. doi: 10.1111/epi.17263.
PubMed Abstract available

ARROTTA K, Reyes A, Kaestner E, McDonald CR, et al
Cognitive Phenotypes in Frontal Lobe Epilepsy.
Epilepsia. 2022 Apr 16. doi: 10.1111/epi.17260.
PubMed Abstract available

HERZOG AG
The Association between Family History of Alcohol Use Disorder and Catamenial Epilepsy.
Epilepsia. 2022 Apr 15. doi: 10.1111/epi.17261.
PubMed Abstract available

STIER C, Loose M, Kotikalapudi R, Elshahabi A, et al
Combined electrophysiological and morphological phenotypes in patients with genetic generalized epilepsy and their healthy siblings.
Epilepsia. 2022 Apr 13. doi: 10.1111/epi.17258.
PubMed Abstract available

SOH MS, Bagnall RD, Semsarian C, Scheffer IE, et al
Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death.
Epilepsia. 2022 Apr 9. doi: 10.1111/epi.17254.
PubMed Abstract available

CHEN Z, Yu W, Xu R, Karoly PJ, et al
Ambient air pollution and epileptic seizures: a panel study in Australia.
Epilepsia. 2022 Apr 8. doi: 10.1111/epi.17253.
PubMed Abstract available

O'HARA NB, Lee MH, Juhasz C, Asano E, et al
Diffusion tractography predicts propagated high-frequency activity during epileptic spasms.
Epilepsia. 2022 Apr 7. doi: 10.1111/epi.17251.
PubMed Abstract available

MEDEL-MATUS JS, Lagishetty V, Santana-Gomez C, Shin D, et al
Susceptibility to epilepsy after traumatic brain injury is associated with preexistent gut microbiome profile.
Epilepsia. 2022 Apr 2. doi: 10.1111/epi.17248.
PubMed Abstract available

HURLEY EN, Ellaway CJ, Johnson AM, Truong L, et al
The efficacy and safety of cannabidivarin treatment on epilepsy in girls with Rett syndrome: A phase I clinical trial.
Epilepsia. 2022 Apr 1. doi: 10.1111/epi.17247.
PubMed Abstract available

CANET G, Zub E, Zussy C, Hernandez C, et al
Seizure activity triggers tau hyperphosphorylation and amyloidogenic pathways.
Epilepsia. 2022;63:919-935.
PubMed Abstract available

KANNER AM, Irving LT, Cajigas I, Saporta A, et al
Long-term seizure and psychiatric outcomes following laser ablation of mesial temporal structures.
Epilepsia. 2022;63:812-823.
PubMed Abstract available

ALCOREZA O, Jagarlamudi S, Savoia A, Campbell SL, et al
Sulfasalazine decreases astrogliosis-mediated seizure burden.
Epilepsia. 2022;63:844-854.
PubMed Abstract available

SPERLING MR, Wheless JW, Hogan RE, Dlugos D, et al
Use of second doses of Valtoco(R) (diazepam nasal spray) across 24 hours after the initial dose for out-of-hospital seizure clusters: Results from a phase 3, open-label, repeat-dose safety study.
Epilepsia. 2022;63:836-843.
PubMed Abstract available

March 2022

HEERS M, Bottcher S, Kalina A, Katletz S, et al
Detection of interictal epileptiform discharges in an extended scalp EEG array and high-density EEG - A prospective multicenter study.
Epilepsia. 2022 Mar 31. doi: 10.1111/epi.17246.
PubMed Abstract available

TOUMA L, Dansereau B, Chan AY, Jette N, et al
Neurostimulation in People with Drug-Resistant Epilepsy: Systematic Review and Meta-Analysis from the ILAE Surgical Therapies Commission.
Epilepsia. 2022 Mar 30. doi: 10.1111/epi.17243.
PubMed Abstract available

VEDERHUS J, Husebye ESN, Eid K, Gilhus NE, et al
Prevalence of self-reported emotional, physical, and sexual abuse and association with fear of childbirth in pregnant women with epilepsy - The Norwegian Mother, Father and Child Cohort Study.
Epilepsia. 2022 Mar 30. doi: 10.1111/epi.17242.
PubMed Abstract available

CHOI JY, Krishnan B, Hu S, Martinez D, et al
Using magnetic resonance fingerprinting to characterize periventricular nodular heterotopias in pharmacoresistant epilepsy.
Epilepsia. 2022 Mar 28. doi: 10.1111/epi.17191.
PubMed Abstract available

CHANG YC, Nouri MN, Mirsattari S, Burneo JG, et al
"Obvious" indications for Neural antibody testing in Epilepsy or Seizures: The ONES checklist.
Epilepsia. 2022 Mar 27. doi: 10.1111/epi.17238.
PubMed Abstract available

LUCKETT PH, Maccotta L, Lee JJ, Park KY, et al
Deep learning resting state fMRI lateralization of temporal lobe epilepsy.
Epilepsia. 2022 Mar 23. doi: 10.1111/epi.17233.
PubMed Abstract available

NEHLIG A, Sperling MR
An interview with Carmen De Caro, 2022 Epilepsia Prize Winner for Basic Science.
Epilepsia. 2022 Mar 21. doi: 10.1111/epi.17221.
PubMed

NEHLIG A, Sperling MR
An interview with Margherita Contento, 2022 Epilepsia Prize winner for clinical research.
Epilepsia. 2022 Mar 21. doi: 10.1111/epi.17222.
PubMed

NAWFAL O, Toufaili H, Dib G, Dirani M, et al
New Onset Refractory Status Epilepticus as an Early Manifestation of Multisystem Inflammatory Syndrome in Adults after Covid-19.
Epilepsia. 2022 Mar 20. doi: 10.1111/epi.17231.
PubMed Abstract available

WILLEMS LM, Hochbaum M, Zollner JP, Schulz J, et al
Trends in resource utilization and cost of illness in patients with active epilepsy in Germany from 2003 to 2020.
Epilepsia. 2022 Mar 19. doi: 10.1111/epi.17229.
PubMed Abstract available

TERMAN SW, Youngerman BE, Choi H, Burke JF, et al
Antiseizure medication treatment pathways in US Medicare beneficiaries with newly treated epilepsy.
Epilepsia. 2022 Mar 16. doi: 10.1111/epi.17226.
PubMed Abstract available

KLODOWSKI DA, George BJ, Sperling MR
Seizure Latency and Epilepsy Localization as Predictors of Recurrence Following Epilepsy Surgery.
Epilepsia. 2022 Mar 14. doi: 10.1111/epi.17224.
PubMed Abstract available

SINCLAIR B, Cahill V, Seah J, Kitchen A, et al
Machine Learning Approaches for Imaging-Based Prognostication of the Outcome of Surgery for Mesial Temporal Lobe Epilepsy.
Epilepsia. 2022 Mar 10. doi: 10.1111/epi.17217.
PubMed Abstract available

SAVAGE SA, Baker J, Milton F, Butler C, et al
Clinical outcomes in Transient Epileptic Amnesia: a 10-year follow-up cohort study of 47 cases.
Epilepsia. 2022 Mar 6. doi: 10.1111/epi.17214.
PubMed Abstract available

WANG B, Wang H, Cen Z, Yuan J, et al
White matter alterations in familial cortical myoclonic tremor with epilepsy type 1.
Epilepsia. 2022 Mar 5. doi: 10.1111/epi.17213.
PubMed Abstract available

NOYMAN I, Ekstein D, Fahoum F, Herskovitz M, et al
Using nirmatrelvir/ritonavir in patients with epilepsy: an update from the Israeli ILAE Chapter.
Epilepsia. 2022 Mar 3. doi: 10.1111/epi.17212.
PubMed Abstract available

SCHOONJANS AS, Roosens L, Dewals W, Paelinck BP, et al
Therapeutic drug monitoring of fenfluramine in clinical practice: Pharmacokinetic variability and impact of concomitant antiseizure medications.
Epilepsia. 2022;63:686-696.
PubMed Abstract available

STERIADE C, Sperling MR, DiVentura B, Lozano M, et al
Proposal for an updated seizure classification framework in clinical trials.
Epilepsia. 2022;63:565-572.
PubMed Abstract available

BACHOUR K, House AA, Andrade DM, Connolly M, et al
Adults with tuberous sclerosis complex: A distinct patient population.
Epilepsia. 2022;63:663-671.
PubMed Abstract available

February 2022

WAHBY S, Lawal OA, Sajobi TT, Keezer MR, et al
Validity and reliability of global ratings of satisfaction with epilepsy surgery.
Epilepsia. 2022 Feb 27. doi: 10.1111/epi.17184.
PubMed Abstract available

PARKER JJ, Zhang Y, Fatemi P, Halpern CH, et al
Antiseizure medication use and medical resource utilization after resective epilepsy surgery in children in the United States: A contemporary nationwide cross-sectional cohort analysis.
Epilepsia. 2022 Feb 25. doi: 10.1111/epi.17180.
PubMed Abstract available

VAN VLIET EA, Marchi N
Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging.
Epilepsia. 2022 Feb 25. doi: 10.1111/epi.17210.
PubMed Abstract available

FARKAS MK, Kang H, Fogarasi A, Bozorg A, et al
Pharmacokinetics, safety, and tolerability of intravenous brivaracetam in pediatric patients with epilepsy: An open-label trial.
Epilepsia. 2022 Feb 23. doi: 10.1111/epi.17187.
PubMed Abstract available

BEGLEY C, Wagner RG, Abraham A, Beghi E, et al
The global cost of epilepsy: A systematic review and extrapolation.
Epilepsia. 2022 Feb 23. doi: 10.1111/epi.17165.
PubMed Abstract available

WILLEMS LM, Hochbaum M, Frey K, Schulz J, et al
Multicenter, cross-sectional study of the costs of illness and cost-driving factors in adult patients with epilepsy.
Epilepsia. 2022 Feb 22. doi: 10.1111/epi.17174.
PubMed Abstract available

ZHANG L, Hall M, Lam SK
Hospital costs associated with vagus nerve stimulation and medical treatment in pediatric patients with refractory epilepsy.
Epilepsia. 2022 Feb 21. doi: 10.1111/epi.17208.
PubMed Abstract available

ATALAR AC, Turk BG, Ekizoglu E, Kurt Gok D, et al
Headache in idiopathic/genetic epilepsies: Cluster analysis in a large cohort.
Epilepsia. 2022 Feb 21. doi: 10.1111/epi.17205.
PubMed Abstract available

KURAL MA, Jing J, Furbass F, Perko H, et al
Accurate identification of EEG recordings with interictal epileptiform discharges using a hybrid approach: Artificial intelligence supervised by human experts.
Epilepsia. 2022 Feb 20. doi: 10.1111/epi.17206.
PubMed Abstract available

BINDING LP, Dasgupta D, Giampiccolo D, Duncan JS, et al
Structure and Function of Language Networks in Temporal Lobe Epilepsy.
Epilepsia. 2022 Feb 20. doi: 10.1111/epi.17204.
PubMed Abstract available

BAYAT A, de Valles-Ibanez G, Pendziwiat M, Knaus A, et al
PIGN encephalopathy: Characterizing the epileptology.
Epilepsia. 2022 Feb 18. doi: 10.1111/epi.17173.
PubMed Abstract available

SCHRAEGLE WA, Tillman R, Ailion A, Babajani-Feremi A, et al
Behavioral phenotypes of pediatric temporal lobe epilepsy.
Epilepsia. 2022 Feb 17. doi: 10.1111/epi.17193.
PubMed Abstract available

STEINBRENNER M, Duncan JS, Dickson J, Rathore C, et al
Utility of 18F-fluorodeoxyglucose positron emission tomography in presurgical evaluation of patients with epilepsy: A multicenter study.
Epilepsia. 2022 Feb 15. doi: 10.1111/epi.17194.
PubMed Abstract available

BARBA C, Rheims S, Minotti L, Grisotto L, et al
Surgical outcome of temporal plus epilepsy is improved by multilobar resection.
Epilepsia. 2022 Feb 15. doi: 10.1111/epi.17185.
PubMed Abstract available

VOGEL FD, Krenn M, Westphal DS, Graf E, et al
A de novo missense variant in GABRA4 alters receptor function in an epileptic and neurodevelopmental phenotype.
Epilepsia. 2022 Feb 12. doi: 10.1111/epi.17188.
PubMed Abstract available

TRIPLET EM, Nickels K, Wong-Kisiel L, Fine A, et al
A tale of two cohorts: Differing outcomes in infantile-onset focal epilepsy.
Epilepsia. 2022 Feb 10. doi: 10.1111/epi.17181.
PubMed Abstract available

FISHER RS, Acharya JN, Baumer FM, French JA, et al
Visually sensitive seizures: An updated review by the Epilepsy Foundation.
Epilepsia. 2022 Feb 7. doi: 10.1111/epi.17175.
PubMed Abstract available

SOPIC D, Teijeiro T, Atienza D, Aminifar A, et al
Personalized seizure signature: An interpretable approach to false alarm reduction for long-term epileptic seizure detection.
Epilepsia. 2022 Feb 3. doi: 10.1111/epi.17176.
PubMed Abstract available

PIRONI V, Ciccone O, Beghi E, Paragua-Zuellig H, et al
Survey on the worldwide availability and affordability of antiseizure medications: Report of the ILAE Task Force on Access to Treatment.
Epilepsia. 2022;63:335-351.
PubMed Abstract available

BERMAN E, Noyman I, Medvedovsky M, Ekstein D, et al
Not your usual drug-drug interactions: Monoclonal antibody-based therapeutics may interact with antiseizure medications.
Epilepsia. 2022;63:271-289.
PubMed Abstract available

GRUBER VE, Luinenburg MJ, Colleselli K, Endmayr V, et al
Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions.
Epilepsia. 2022;63:364-374.
PubMed Abstract available

LEONARD H, Junaid M, Wong K, Aimetti AA, et al
Influences on the trajectory and subsequent outcomes in CDKL5 deficiency disorder.
Epilepsia. 2022;63:352-363.
PubMed Abstract available

ROCHTUS AM, Herijgers D, Jansen K, Decallonne B, et al
Antiseizure medications and thyroid hormone homeostasis: Literature review and practical recommendations.
Epilepsia. 2022;63:259-270.
PubMed Abstract available

January 2022

MOLTEBERG E, Tauboll E, Kverneland M, Iversen PO, et al
Substantial early changes in bone and calcium metabolism among adult pharmacoresistant epilepsy patients on a modified Atkins diet.
Epilepsia. 2022 Jan 28. doi: 10.1111/epi.17169.
PubMed Abstract available

ROYER J, Bernhardt BC, Lariviere S, Gleichgerrcht E, et al
Epilepsy and brain network hubs.
Epilepsia. 2022 Jan 28. doi: 10.1111/epi.17171.
PubMed Abstract available

SIRIRATNAM P, Foster E, Shakhatreh L, Neal A, et al
The effect of epilepsy surgery on productivity: A systematic review and meta-analysis.
Epilepsia. 2022 Jan 27. doi: 10.1111/epi.17172.
PubMed Abstract available

BOULOGNE S, Pizzo F, Chatard B, Roehri N, et al
Functional connectivity and epileptogenicity of nodular heterotopias: A single-pulse stimulation study.
Epilepsia. 2022 Jan 19. doi: 10.1111/epi.17168.
PubMed Abstract available

LING DSF, Yang L, Goodman JH
Brivaracetam prevents the development of epileptiform activity when administered early after cortical neurotrauma in rats.
Epilepsia. 2022 Jan 17. doi: 10.1111/epi.17167.
PubMed Abstract available

KOKO M, Motelow JE, Stanley KE, Bobbili DR, et al
Association of ultra-rare coding variants with genetic generalized epilepsy: A case-control whole exome sequencing study.
Epilepsia. 2022 Jan 15. doi: 10.1111/epi.17166.
PubMed Abstract available

KWON CS, Wagner RG, Carpio A, Jette N, et al
The worldwide epilepsy treatment gap: A systematic review and recommendations for revised definitions - A report from the ILAE Epidemiology Commission.
Epilepsia. 2022 Jan 10. doi: 10.1111/epi.17112.
PubMed Abstract available

SCHEID BH, Bernabei JM, Khambhati AN, Mouchtaris S, et al
Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment.
Epilepsia. 2022 Jan 7. doi: 10.1111/epi.17163.
PubMed Abstract available

MERTEN JE, Villarrubia SA, Holly KS, Kemp AS, et al
The use of rodent models to better characterize the relationship among epilepsy, sleep, and memory.
Epilepsia. 2022 Jan 5. doi: 10.1111/epi.17161.
PubMed Abstract available

KWON CS, Jacoby A, Ali A, Austin J, et al
Systematic review of frequency of felt and enacted stigma in epilepsy and determining factors and attitudes toward persons living with epilepsy-Report from the International League Against Epilepsy Task Force on Stigma in Epilepsy.
Epilepsia. 2022 Jan 5. doi: 10.1111/epi.17135.
PubMed Abstract available

AUSTIN JK, Birbeck G, Parko K, Kwon CS, et al
Epilepsy-related stigma and attitudes: Systematic review of screening instruments and interventions - Report by the International League Against Epilepsy Task Force on Stigma in Epilepsy.
Epilepsia. 2022 Jan 5. doi: 10.1111/epi.17133.
PubMed Abstract available

GHOLIPOUR T, You X, Stufflebeam SM, Loew M, et al
Common functional connectivity alterations in focal epilepsies identified by machine learning.
Epilepsia. 2022 Jan 4. doi: 10.1111/epi.17160.
PubMed Abstract available

VETKAS A, Fomenko A, Germann J, Sarica C, et al
Deep brain stimulation targets in epilepsy: Systematic review and meta-analysis of anterior and centromedian thalamic nuclei and hippocampus.
Epilepsia. 2022 Jan 3. doi: 10.1111/epi.17157.
PubMed Abstract available

WAGSTYL K, Whitaker K, Raznahan A, Seidlitz J, et al
Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study.
Epilepsia. 2022;63:61-74.
PubMed Abstract available

XU Y, Wan L, He W, Wang YY, et al
Risk of vigabatrin-associated brain abnormalities on MRI: A retrospective and controlled study.
Epilepsia. 2022;63:120-129.
PubMed Abstract available

SULLIVAN J, Specchio N, Devinsky O, Auvin S, et al
Fenfluramine significantly reduces day-to-day seizure burden by increasing number of seizure-free days and time between seizures in patients with Dravet syndrome: A time-to-event analysis.
Epilepsia. 2022;63:130-138.
PubMed Abstract available

December 2021

SHAH PD, Yun M, Wu A, Arnesen RA, et al
Pediatric Epilepsy Learning Healthcare System Quality of Life (PELHS-QOL-2): A novel health-related quality of life prompt for children with epilepsy.
Epilepsia. 2021 Dec 31. doi: 10.1111/epi.17156.
PubMed Abstract available

CHAN HY, Wijnen BFM, Majoie MHJM, Evers SMAA, et al
Economic evaluation of deep brain stimulation compared with vagus nerve stimulation and usual care for patients with refractory epilepsy: A lifetime decision analytic model.
Epilepsia. 2021 Dec 30. doi: 10.1111/epi.17158.
PubMed Abstract available

KOVERMANN P, Kolobkova Y, Franzen A, Fahlke C, et al
Mutations associated with epileptic encephalopathy modify EAAT2 anion channel function.
Epilepsia. 2021 Dec 28. doi: 10.1111/epi.17154.
PubMed Abstract available

KOSTOV KH, Kostov H, Larsson PG, Henning O, et al
Norwegian population-based study of long-term effects, safety, and predictors of response of vagus nerve stimulation treatment in drug-resistant epilepsy: The NORPulse study.
Epilepsia. 2021 Dec 21. doi: 10.1111/epi.17152.
PubMed Abstract available

WANG M, Perera K, Josephson CB, Lamidi M, et al
Association between antiseizure medications and quality of life in epilepsy: A mediation analysis.
Epilepsia. 2021 Dec 20. doi: 10.1111/epi.17153.
PubMed Abstract available

ZWEIPHENNING WJEM, von Ellenrieder N, Dubeau F, Martineau L, et al
Correcting for physiological ripples improves epileptic focus identification and outcome prediction.
Epilepsia. 2021 Dec 16. doi: 10.1111/epi.17145.
PubMed Abstract available

LAGHOUATI E, Studer F, Depaulis A, Guillemain I, et al
Early alterations of the neuronal network processing whisker-related sensory signal during absence epileptogenesis.
Epilepsia. 2021 Dec 16. doi: 10.1111/epi.17151.
PubMed Abstract available

TATUM WO, Mani J, Jin K, Halford JJ, et al
Minimum standards for inpatient long-term video-electroencephalographic monitoring: A clinical practice guideline of the International League Against Epilepsy and International Federation of Clinical Neurophysiology.
Epilepsia. 2021 Dec 13. doi: 10.1111/epi.16977.
PubMed Abstract available

PUTEIKIS K, Wolf P, Mameniskiene R
Accelerated long-term forgetting in adult patients with genetic generalized epilepsy.
Epilepsia. 2021 Dec 10. doi: 10.1111/epi.17144.
PubMed Abstract available

SHEIDLEY BR, Malinowski J, Bergner AL, Bier L, et al
Genetic testing for the epilepsies: A systematic review.
Epilepsia. 2021 Dec 10. doi: 10.1111/epi.17141.
PubMed Abstract available

WANG K, Xie F, Liu C, Tan L, et al
Abnormal functional connectivity profiles predict drug responsiveness in patients with temporal lobe epilepsy.
Epilepsia. 2021 Dec 7. doi: 10.1111/epi.17142.
PubMed Abstract available

MULA M, Brodie MJ, de Toffol B, Guekht A, et al
ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy.
Epilepsia. 2021 Dec 5. doi: 10.1111/epi.17140.
PubMed Abstract available

COLEMAN H, McIntosh A, Wilson SJ
"Do I still have epilepsy?" Epilepsy identity 15-20 years after anterior temporal lobectomy.
Epilepsia. 2021 Dec 4. doi: 10.1111/epi.17143.
PubMed Abstract available

JANCOVSKI N, Baldwin T, Orford M, Li M, et al
Protective effects of medium chain triglyceride diet in a mouse model of Dravet syndrome.
Epilepsia. 2021;62:3131-3142.
PubMed Abstract available

FRANZ DN, Lawson JA, Yapici Z, Ikeda H, et al
Adjunctive everolimus therapy for tuberous sclerosis complex-associated refractory seizures: Results from the postextension phase of EXIST-3.
Epilepsia. 2021;62:3029-3041.
PubMed Abstract available

GABALLA A, Woermann FG, Cloppenborg T, Kalbhenn T, et al
Clinical characteristics and postoperative seizure outcome in patients with mild malformation of cortical development and oligodendroglial hyperplasia.
Epilepsia. 2021;62:2920-2931.
PubMed Abstract available

FEJA M, Meller S, Deking LS, Kaczmarek E, et al
OV329, a novel highly potent gamma-aminobutyric acid aminotransferase inactivator, induces pronounced anticonvulsant effects in the pentylenetetrazole seizure threshold test and in amygdala-kindled rats.
Epilepsia. 2021;62:3091-3104.
PubMed Abstract available

PUKA K, Jones M, Mathern GW
Functional cognitive and language outcomes after cerebral hemispherectomy for hemimegalencephaly.
Epilepsia. 2021;62:2932-2940.
PubMed Abstract available

November 2021

KO AL, Tong APS, Mossa-Basha M, Weaver KE, et al
Effects of laser interstitial thermal therapy for mesial temporal lobe epilepsy on the structural connectome and its relationship to seizure freedom.
Epilepsia. 2021 Nov 24. doi: 10.1111/epi.17059.
PubMed Abstract available

KUMAR A, Martin R, Chen W, Bauerschmidt A, et al
Simulated driving in the epilepsy monitoring unit: Effects of seizure type, consciousness, and motor impairment.
Epilepsia. 2021 Nov 24. doi: 10.1111/epi.17136.
PubMed Abstract available

GIOVANNINI G, Bedin R, Ferraro D, Vaudano AE, et al
Serum neurofilament light as biomarker of seizure-related neuronal injury in status epilepticus.
Epilepsia. 2021 Nov 21. doi: 10.1111/epi.17132.
PubMed Abstract available

LU L, Zhang Q, Xiao J, Zhang Y, et al
COVID-19 vaccine take-up rate and safety in adults with epilepsy: Data from a multicenter study in China.
Epilepsia. 2021 Nov 21. doi: 10.1111/epi.17138.
PubMed Abstract available

ASADI-POOYA AA, Beniczky S, Rubboli G, Sperling MR, et al
The EpiPick algorithm to select appropriate antiseizure medications in patients with epilepsy: Validation studies and updates.
Epilepsia. 2021 Nov 19. doi: 10.1111/epi.17129.
PubMed

STEFANIDOU M, Himali JJ, Devinsky O, Romero JR, et al
Vascular risk factors as predictors of epilepsy in older age: The Framingham Heart Study.
Epilepsia. 2021 Nov 16. doi: 10.1111/epi.17108.
PubMed Abstract available

PERRY MS, Shandley S, Perelman M, Singh RK, et al
Surgical evaluation in children <3 years of age with drug-resistant epilepsy: Patient characteristics, diagnostic utilization, and potential for treatment delays.
Epilepsia. 2021 Nov 15. doi: 10.1111/epi.17124.
PubMed Abstract available

MICELI F, Guerrini R, Nappi M, Soldovieri MV, et al
Distinct epilepsy phenotypes and response to drugs in KCNA1 gain- and loss-of function variants.
Epilepsia. 2021 Nov 14. doi: 10.1111/epi.17118.
PubMed Abstract available

SENEVIRATNE U, Cook M, D'Souza W
Brainwaves beyond diagnosis: Wider applications of electroencephalography in idiopathic generalized epilepsy.
Epilepsia. 2021 Nov 10. doi: 10.1111/epi.17119.
PubMed Abstract available

ZELIG D, Goldberg I, Shor O, Ben Dor S, et al
Paroxysmal slow wave events predict epilepsy following a first seizure.
Epilepsia. 2021 Nov 9. doi: 10.1111/epi.17110.
PubMed Abstract available

BUTTLE SG, Muir K, Dehnoei S, Webster R, et al
Referral practices for epilepsy surgery in pediatric patients: A North American Study.
Epilepsia. 2021 Nov 8. doi: 10.1111/epi.17122.
PubMed Abstract available

WALKER LE, Sills GJ, Jorgensen A, Alapirtti T, et al
High-mobility group box 1 as a predictive biomarker for drug-resistant epilepsy: A proof-of-concept study.
Epilepsia. 2021 Nov 8. doi: 10.1111/epi.17116.
PubMed Abstract available

SPECCHIO N, Di Micco V, Trivisano M, Ferretti A, et al
The epilepsy-autism spectrum disorder phenotype in the era of molecular genetics and precision therapy.
Epilepsia. 2021 Nov 6. doi: 10.1111/epi.17115.
PubMed Abstract available

HOLTHAUSEN H, Coras R, Tang Y, Bai L, et al
Multilobar unilateral hypoplasia with emphasis on the posterior quadrant and severe epilepsy in children with FCD ILAE Type 1A.
Epilepsia. 2021 Nov 6. doi: 10.1111/epi.17114.
PubMed Abstract available

LEE CC, Chou CC, Hsiao FJ, Chen YH, et al
Pilot study of focused ultrasound for drug-resistant epilepsy.
Epilepsia. 2021 Nov 2. doi: 10.1111/epi.17105.
PubMed Abstract available

34(th) International Epilepsy Congress Virtual 28 August - 1 September 2021.
Epilepsia. 2021;62 Suppl 3:1-364.
PubMed

CHIANG S, Fan JM, Rao VR
Bilateral temporal lobe epilepsy: How many seizures are required in chronic ambulatory electrocorticography to estimate the laterality ratio?
Epilepsia. 2021 Nov 1. doi: 10.1111/epi.17113.
PubMed Abstract available

LAYER N, Brandes J, Luhrs PJ, Wuttke TV, et al
The effect of lamotrigine and other antiepileptic drugs on respiratory rhythm generation in the pre-Botzinger complex.
Epilepsia. 2021;62:2790-2803.
PubMed Abstract available

TARIGHATI RASEKHI R, Devlin KN, Sperling MR, Nei M, et al
Response: SUDEP-7 Inventory: Validation in a retrospective cohort study.
Epilepsia. 2021;62:2873-2874.
PubMed

KERR WT, Markovic D, DeGiorgio CM
SUDEP-7 Inventory: Validation in a retrospective cohort study.
Epilepsia. 2021;62:2871-2872.
PubMed

SHAHABI H, Taylor K, Hirfanoglu T, Koneru S, et al
Effective connectivity differs between focal cortical dysplasia types I and II.
Epilepsia. 2021;62:2753-2765.
PubMed Abstract available

SHIROZU H, Masuda H, Kameyama S
Long-term seizure outcomes in patients with hypothalamic hamartoma treated by stereotactic radiofrequency thermocoagulation.
Epilepsia. 2021;62:2697-2706.
PubMed Abstract available

HAWKINS NA, Jurado M, Thaxton TT, Duarte SE, et al
Soticlestat, a novel cholesterol 24-hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice.
Epilepsia. 2021;62:2845-2857.
PubMed Abstract available

SWINNEN L, Chatzichristos C, Jansen K, Lagae L, et al
Accurate detection of typical absence seizures in adults and children using a two-channel electroencephalographic wearable behind the ears.
Epilepsia. 2021;62:2741-2752.
PubMed Abstract available

MARTIN RA, Cukiert A, Blumenfeld H
Short-term changes in cortical physiological arousal measured by electroencephalography during thalamic centromedian deep brain stimulation.
Epilepsia. 2021;62:2604-2614.
PubMed Abstract available

October 2021

BOURDILLON P, Bulteau C, Dorfmuller G, Ferrand-Sorbets S, et al
Vertical hemispherotomy for drug-resistant epilepsy: Toward confirmation of the HOPS study.
Epilepsia. 2021 Oct 30. doi: 10.1111/epi.17111.
PubMed

KAMITAKI BK, Janmohamed M, Kandula P, Elder C, et al
Clinical and EEG factors associated with antiseizure medication resistance in idiopathic generalized epilepsy.
Epilepsia. 2021 Oct 27. doi: 10.1111/epi.17104.
PubMed Abstract available

FASANO A, Eliashiv D, Herman ST, Lundstrom BN, et al
Experience and consensus on stimulation of the anterior nucleus of thalamus for epilepsy.
Epilepsia. 2021 Oct 26. doi: 10.1111/epi.17094.
PubMed Abstract available

BRANDNER S, Schroeter S, Caliskan G, Salar S, et al
Glucocorticoid modulation of synaptic plasticity in the human temporal cortex of epilepsy patients: Does chronic stress contribute to memory impairment?
Epilepsia. 2021 Oct 23. doi: 10.1111/epi.17107.
PubMed Abstract available

DEMUTH S, Dinkelacker V
Toward personalized machine learning approaches in care of patients with epilepsy.
Epilepsia. 2021 Oct 21. doi: 10.1111/epi.17093.
PubMed

BAUMANN SM, Semmlack S, Rybitschka A, Kliem PSC, et al
Prolonged mechanical ventilation in patients with terminated status epilepticus and outcome: An observational cohort study.
Epilepsia. 2021 Oct 18. doi: 10.1111/epi.17100.
PubMed Abstract available

TRIMMEL K, Vos SB, Caciagli L, Xiao F, et al
Decoupling of functional and structural language networks in temporal lobe epilepsy.
Epilepsia. 2021 Oct 12. doi: 10.1111/epi.17098.
PubMed Abstract available

KNOX KM, Zierath DK, White HS, Barker-Haliski M, et al
Continuous seizure emergency evoked in mice with pharmacological, electrographic, and pathological features distinct from status epilepticus.
Epilepsia. 2021 Oct 8. doi: 10.1111/epi.17089.
PubMed Abstract available

STRZELCZYK A, Zaveta C, von Podewils F, Moddel G, et al
Long-term efficacy, tolerability, and retention of brivaracetam in epilepsy treatment: A longitudinal multicenter study with up to 5 years of follow-up.
Epilepsia. 2021 Oct 4. doi: 10.1111/epi.17087.
PubMed Abstract available

BENICZKY S, Asadi-Pooya AA, Perucca E, Rubboli G, et al
A web-based algorithm to rapidly classify seizures for the purpose of drug selection.
Epilepsia. 2021;62:2474-2484.
PubMed Abstract available

GREGG NM, Marks VS, Sladky V, Lundstrom BN, et al
Anterior nucleus of the thalamus seizure detection in ambulatory humans.
Epilepsia. 2021;62:e158-e164.
PubMed Abstract available

SCHEFFER IE, Halford JJ, Miller I, Nabbout R, et al
Add-on cannabidiol in patients with Dravet syndrome: Results of a long-term open-label extension trial.
Epilepsia. 2021;62:2505-2517.
PubMed Abstract available

STRZELCZYK A, Pringsheim M, Mayer T, Polster T, et al
Efficacy, tolerability, and retention of fenfluramine for the treatment of seizures in patients with Dravet syndrome: Compassionate use program in Germany.
Epilepsia. 2021;62:2518-2527.
PubMed Abstract available

DICKEY AS, Pedersen NP
Low statistical power in a study predicting seizure outcome.
Epilepsia. 2021;62:2565-2566.
PubMed

KANG JY, Yenokyan G, Sperling MR, Nei M, et al
Response: "Low statistical power in a study predicting seizure outcome".
Epilepsia. 2021;62:2567.
PubMed

MANOUZE H, Ghestem A, Bennis M, Sokar Z, et al
Antiseizure effects of Anacyclus pyrethrum in socially isolated rats with and without a positive handling strategy.
Epilepsia. 2021;62:2551-2564.
PubMed Abstract available

TAN G, Li X, Niu R, Wang H, et al
Functional connectivity of the thalamocortical circuit in patients with seizure relapse after antiseizure medication withdrawal.
Epilepsia. 2021;62:2463-2473.
PubMed Abstract available

FREDWALL M, Terry D, Enciso L, Burch MM, et al
Outcomes of children and adolescents 1 year after being seen in a multidisciplinary psychogenic nonepileptic seizures clinic.
Epilepsia. 2021;62:2528-2538.
PubMed Abstract available

LIU DD, Lauro PM, Phillips RK 3rd, Leary OP, et al
Two-trajectory laser amygdalohippocampotomy: Anatomic modeling and initial seizure outcomes.
Epilepsia. 2021;62:2344-2356.
PubMed Abstract available

MITSUHASHI T, Sonoda M, Sakakura K, Jeong JW, et al
Dynamic tractography-based localization of spike sources and animation of spike propagations.
Epilepsia. 2021;62:2372-2384.
PubMed Abstract available

VANDECASTEELE K, De Cooman T, Chatzichristos C, Cleeren E, et al
The power of ECG in multimodal patient-specific seizure monitoring: Added value to an EEG-based detector using limited channels.
Epilepsia. 2021;62:2333-2343.
PubMed Abstract available

September 2021

SILVA JC, Vivash L, Malpas CB, Hao Y, et al
Low prevalence of amyloid and tau pathology in drug-resistant temporal lobe epilepsy.
Epilepsia. 2021 Sep 30. doi: 10.1111/epi.17086.
PubMed Abstract available

HUSEBYE ESN, Riedel B, Bjorke-Monsen AL, Spigset O, et al
Vitamin B status and association with antiseizure medication in pregnant women with epilepsy.
Epilepsia. 2021 Sep 30. doi: 10.1111/epi.17076.
PubMed Abstract available

KHOO A, de Tisi J, Mannan S, O'Keeffe AG, et al
Reasons for not having epilepsy surgery.
Epilepsia. 2021 Sep 23. doi: 10.1111/epi.17083.
PubMed Abstract available

VIBHOLM AK, Dietz MJ, Beniczky S, Christensen J, et al
Activated N-methyl-D-aspartate receptor ion channels detected in focal epilepsy with [(18) F]GE-179 positron emission tomography.
Epilepsia. 2021 Sep 23. doi: 10.1111/epi.17074.
PubMed Abstract available

MBIZVO GK, Schnier C, Simpson CR, Chin RFM, et al
A national study of epilepsy-related deaths in Scotland: Trends, mechanisms, and avoidable deaths.
Epilepsia. 2021 Sep 19. doi: 10.1111/epi.17065.
PubMed Abstract available

FARINA MG, Sandhu MRS, Parent M, Sanganahalli BG, et al
Small loci of astroglial glutamine synthetase deficiency in the postnatal brain cause epileptic seizures and impaired functional connectivity.
Epilepsia. 2021 Sep 18. doi: 10.1111/epi.17072.
PubMed Abstract available

SABOO KV, Balzekas I, Kremen V, Varatharajah Y, et al
Leveraging electrophysiologic correlates of word encoding to map seizure onset zone in focal epilepsy: Task-dependent changes in epileptiform activity, spectral features, and functional connectivity.
Epilepsia. 2021 Sep 18. doi: 10.1111/epi.17067.
PubMed Abstract available

PING X, Chai Z, Wang W, Ma C, et al
Blocking receptor for advanced glycation end products (RAGE) or toll-like receptor 4 (TLR4) prevents posttraumatic epileptogenesis in mice.
Epilepsia. 2021 Sep 18. doi: 10.1111/epi.17069.
PubMed Abstract available

FALLAH A, Lewis E, Ibrahim GM, Kola O, et al
Comparison of the real-world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug-resistant epilepsy: A post hoc analysis of the HOPS study.
Epilepsia. 2021 Sep 12. doi: 10.1111/epi.17021.
PubMed Abstract available

LIN Y, Hu S, Hao X, Duan L, et al
Epilepsy centers in China: Current status and ways forward.
Epilepsia. 2021 Sep 12. doi: 10.1111/epi.17058.
PubMed Abstract available

FADAIE F, Lee HM, Caldairou B, Gill RS, et al
Atypical functional connectome hierarchy impacts cognition in temporal lobe epilepsy.
Epilepsia. 2021 Sep 7. doi: 10.1111/epi.17032.
PubMed Abstract available

QUON RJ, Camp EJ, Meisenhelter S, Song Y, et al
Features of intracranial interictal epileptiform discharges associated with memory encoding.
Epilepsia. 2021 Sep 5. doi: 10.1111/epi.17060.
PubMed Abstract available

BOHOSOVA J, Vajcner J, Jabandziev P, Oslejskova H, et al
MicroRNAs in the development of resistance to antiseizure drugs and their potential as biomarkers in pharmacoresistant epilepsy.
Epilepsia. 2021 Sep 5. doi: 10.1111/epi.17063.
PubMed Abstract available

LINEHAN C, Benson A, Gunko A, Christensen J, et al
Exploring the prevalence and profile of epilepsy across Europe using a standard retrospective chart review: Challenges and opportunities.
Epilepsia. 2021 Sep 2. doi: 10.1111/epi.17057.
PubMed Abstract available

JOSEPHSON CB, Engbers JDT, Sajobi TT, Wiebe S, et al
Adult onset epilepsy is defined by phenotypic clusters with unique comorbidities and risks of death.
Epilepsia. 2021;62:2036-2047.
PubMed Abstract available

LI W, Schneider AL, Scheffer IE
Defining Dravet syndrome: An essential pre-requisite for precision medicine trials.
Epilepsia. 2021;62:2205-2217.
PubMed Abstract available

MENGONI F, Salari V, Kosenkova I, Tsenov G, et al
Gut microbiota modulates seizure susceptibility.
Epilepsia. 2021;62:e153-e157.
PubMed Abstract available

WANG W, Li H, Yan J, Zhang H, et al
Automatic detection of interictal ripples on scalp EEG to evaluate the effect and prognosis of ACTH therapy in patients with infantile spasms.
Epilepsia. 2021;62:2240-2251.
PubMed Abstract available

WICKER E, Forcelli PA
Optogenetic activation of the reticular nucleus of the thalamus attenuates limbic seizures via inhibition of the midline thalamus.
Epilepsia. 2021;62:2283-2296.
PubMed Abstract available

PATEL AD, Mazurkiewicz-Beldzinska M, Chin RF, Gil-Nagel A, et al
Long-term safety and efficacy of add-on cannabidiol in patients with Lennox-Gastaut syndrome: Results of a long-term open-label extension trial.
Epilepsia. 2021;62:2228-2239.
PubMed Abstract available

MADAN COHEN J, Checketts D, Dunayevich E, Gunning B, et al
Time to onset of cannabidiol treatment effects in Dravet syndrome: Analysis from two randomized controlled trials.
Epilepsia. 2021;62:2218-2227.
PubMed Abstract available

FALLAH MS, Dlugosz L, Scott BW, Thompson MD, et al
Antiseizure effects of the cannabinoids in the amygdala-kindling model.
Epilepsia. 2021;62:2274-2282.
PubMed Abstract available

CONTENTO M, Bertaccini B, Biggi M, Magliani M, et al
Prediction of seizure recurrence risk following discontinuation of antiepileptic drugs.
Epilepsia. 2021;62:2159-2170.
PubMed Abstract available

MCGONIGAL A, Bartolomei F, Chauvel P
On seizure semiology.
Epilepsia. 2021;62:2019-2035.
PubMed Abstract available

HAKANSSON S, Karlander M, Larsson D, Mahamud Z, et al
Potential for improved retention rate by personalized antiseizure medication selection: A register-based analysis.
Epilepsia. 2021;62:2123-2132.
PubMed Abstract available

August 2021

SUGA H, Yanagida A, Kanazawa N, Ohara H, et al
Status epilepticus suspected autoimmune: Neuronal surface antibodies and main clinical features.
Epilepsia. 2021 Aug 31. doi: 10.1111/epi.17055.
PubMed Abstract available

BLENKINSOP S, Foley A, Schneider N, Willis J, et al
Carbon emission savings and short-term health care impacts from telemedicine: An evaluation in epilepsy.
Epilepsia. 2021 Aug 31. doi: 10.1111/epi.17046.
PubMed Abstract available

TERMAN SW, Kerr WT, Marcum ZA, Wang L, et al
Antiseizure medication adherence trajectories in Medicare beneficiaries with newly treated epilepsy.
Epilepsia. 2021 Aug 31. doi: 10.1111/epi.17051.
PubMed Abstract available

GAILUS B, Naundorf H, Welzel L, Johne M, et al
Long-term outcome in a noninvasive rat model of birth asphyxia with neonatal seizures: Cognitive impairment, anxiety, epilepsy, and structural brain alterations.
Epilepsia. 2021 Aug 29. doi: 10.1111/epi.17050.
PubMed Abstract available

YOUNGERMAN BE, Mahajan UV, Dyster TG, Srinivasan S, et al
Cost-effectiveness analysis of responsive neurostimulation for drug-resistant focal onset epilepsy.
Epilepsia. 2021 Aug 29. doi: 10.1111/epi.17049.
PubMed Abstract available

BREU M, Hafele C, Trimmel-Schwahofer P, Schmidt WM, et al
The relation of etiology based on the 2017 ILAE classification to the effectiveness of the ketogenic diet in drug-resistant epilepsy in childhood.
Epilepsia. 2021 Aug 28. doi: 10.1111/epi.17052.
PubMed Abstract available

PUHAHN-SCHMEISER B, Leicht K, Gessler F, Freiman TM, et al
Aberrant hippocampal mossy fibers in temporal lobe epilepsy target excitatory and inhibitory neurons.
Epilepsia. 2021 Aug 28. doi: 10.1111/epi.17035.
PubMed Abstract available

CROSS JH, Kwon CS, Asadi-Pooya AA, Balagura G, et al
Epilepsy care during the COVID-19 pandemic.
Epilepsia. 2021 Aug 24. doi: 10.1111/epi.17045.
PubMed Abstract available

BRUNO E, Bottcher S, Viana PF, Amengual-Gual M, et al
Wearable devices for seizure detection: Practical experiences and recommendations from the Wearables for Epilepsy And Research (WEAR) International Study Group.
Epilepsia. 2021 Aug 22. doi: 10.1111/epi.17044.
PubMed Abstract available

SHEEHAN T, Amengual-Gual M, Vasquez A, Abend NS, et al
Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus.
Epilepsia. 2021 Aug 21. doi: 10.1111/epi.17043.
PubMed Abstract available

WHELESS JW, Miller I, Hogan RE, Dlugos D, et al
Final results from a Phase 3, long-term, open-label, repeat-dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy.
Epilepsia. 2021 Aug 21. doi: 10.1111/epi.17041.
PubMed Abstract available

KLOVGAARD M, Lynge TH, Tsiropoulos I, Uldall PV, et al
Sudden unexpected death in epilepsy in persons younger than 50 years: A retrospective nationwide cohort study in Denmark.
Epilepsia. 2021 Aug 21. doi: 10.1111/epi.17037.
PubMed Abstract available

BJELLVI J, Cross JH, Gogou M, Leclercq M, et al
Classification of complications of epilepsy surgery and invasive diagnostic procedures: A proposed protocol and feasibility study.
Epilepsia. 2021 Aug 18. doi: 10.1111/epi.17040.
PubMed Abstract available

LEHN A, Watson E, Ryan EG, Jones M, et al
Psychogenic nonepileptic seizures treated as epileptic seizures in the emergency department.
Epilepsia. 2021 Aug 15. doi: 10.1111/epi.17038.
PubMed Abstract available

BARGUILLA A, Panades-de Oliveira L, Principe A, Rocamora R, et al
SUDEP-3: probable improvement in risk stratification for sudden death in epilepsy.
Epilepsia. 2021 Aug 6. doi: 10.1111/epi.17033.
PubMed

COLEMAN H, McIntosh A, Rayner G, Wilson SJ, et al
Understanding long-term changes in patient identity 15-20 years after surgery for temporal lobe epilepsy.
Epilepsia. 2021 Aug 6. doi: 10.1111/epi.17027.
PubMed Abstract available

DAI XJ, Liu H, Yang Y, Wang Y, et al
Brain network excitatory/inhibitory imbalance is a biomarker for drug-naive Rolandic epilepsy: A radiomics strategy.
Epilepsia. 2021 Aug 3. doi: 10.1111/epi.17011.
PubMed Abstract available

FITZGERALD Z, Morita-Sherman M, Hogue O, Joseph B, et al
Improving the prediction of epilepsy surgery outcomes using basic scalp EEG findings.
Epilepsia. 2021 Aug 2. doi: 10.1111/epi.17024.
PubMed Abstract available

SHEYBANI L, Megevand P, Spinelli L, Benar CG, et al
Slow oscillations open susceptible time windows for epileptic discharges.
Epilepsia. 2021 Aug 2. doi: 10.1111/epi.17020.
PubMed Abstract available

GUMMADAVELLI A, Martin R, Goshay D, Sieu LA, et al
Cortical low-frequency power correlates with behavioral impairment in animal model of focal limbic seizures.
Epilepsia. 2021;62:1960-1970.
PubMed Abstract available

MILJANOVIC N, van Dijk RM, Buchecker V, Potschka H, et al
Metabolomic signature of the Dravet syndrome: A genetic mouse model study.
Epilepsia. 2021;62:2000-2014.
PubMed Abstract available

AKMAN O, Briggs SW, Mowrey WB, Moshe SL, et al
Antiepileptogenic effects of rapamycin in a model of infantile spasms due to structural lesions.
Epilepsia. 2021;62:1985-1999.
PubMed Abstract available

The UK experience of stereoelectroencephalography in children: An analysis of factors predicting the identification of a seizure-onset zone and subsequent seizure freedom.
Epilepsia. 2021;62:1883-1896.
PubMed Abstract available

SHIONO S, Sun H, Batabyal T, Labuz A, et al
Limbic progesterone receptor activity enhances neuronal excitability and seizures.
Epilepsia. 2021;62:1946-1959.
PubMed Abstract available

HALLER JT, Bonnin S, Radosevich J
Rapid administration of undiluted intravenous levetiracetam.
Epilepsia. 2021;62:1865-1870.
PubMed Abstract available

TANG J, El Atrache R, Yu S, Asif U, et al
Seizure detection using wearable sensors and machine learning: Setting a benchmark.
Epilepsia. 2021;62:1807-1819.
PubMed Abstract available

VIANA PF, Remvig LS, Duun-Henriksen J, Glasstetter M, et al
Signal quality and power spectrum analysis of remote ultra long-term subcutaneous EEG.
Epilepsia. 2021;62:1820-1828.
PubMed Abstract available

LAGARDE S, Singh R, Bartolomei F, Guedj E, et al
Insular interictal positron emission tomography hypometabolism in patients with ictal asystole.
Epilepsia. 2021;62:e117-e122.
PubMed Abstract available

July 2021

ALVIM MKM, Morita-Sherman ME, Yasuda CL, Rocha NP, et al
Inflammatory and neurotrophic factor plasma levels are related to epilepsy independently of etiology.
Epilepsia. 2021 Jul 31. doi: 10.1111/epi.17023.
PubMed Abstract available

VIDAURRE J, Albert DVF, Parker W, Naprawa J, et al
Improving time for administration of second-line antiseizure medications for children with generalized convulsive status epilepticus using quality improvement methodology.
Epilepsia. 2021 Jul 30. doi: 10.1111/epi.17026.
PubMed Abstract available

DOERRFUSS JI, Kowski AB, Holtkamp M
Etiology-specific response to antiseizure medication in focal epilepsy.
Epilepsia. 2021 Jul 30. doi: 10.1111/epi.17017.
PubMed Abstract available

SAJOBI TT, Josephson CB, Sawatzky R, Wang M, et al
Quality of Life in Epilepsy: Same questions, but different meaning to different people.
Epilepsia. 2021 Jul 26. doi: 10.1111/epi.17012.
PubMed Abstract available

GIUSSANI G, Bianchi E, Beretta S, Carone D, et al
Comorbidities in patients with epilepsy: Frequency, mechanisms and effects on long-term outcome.
Epilepsia. 2021 Jul 26. doi: 10.1111/epi.17022.
PubMed Abstract available

LEE SJ, Beam DE, Schjetnan AGP, Paul LK, et al
Single-neuron correlate of epilepsy-related cognitive deficits in visual recognition memory in right mesial temporal lobe.
Epilepsia. 2021 Jul 21. doi: 10.1111/epi.17010.
PubMed Abstract available

BERTRAM EH, Edelbroek P
Chronic limbic epilepsy models for therapy discovery: Protocols to improve efficiency.
Epilepsia. 2021 Jul 21. doi: 10.1111/epi.16995.
PubMed Abstract available

AL-FARAJ AO, Pandey S, Herlihy MM, Pang TD, et al
Factors affecting breastfeeding in women with epilepsy.
Epilepsia. 2021 Jul 21. doi: 10.1111/epi.17003.
PubMed Abstract available

BENJUMEDA M, Tan YL, Gonzalez Otarula KA, Chandramohan D, et al
Patient specific prediction of temporal lobe epilepsy surgical outcomes.
Epilepsia. 2021 Jul 18. doi: 10.1111/epi.17002.
PubMed Abstract available

CAHILL PT, Ferro MA, Campbell WN, Ronen GM, et al
Self-esteem mediates mental health outcomes in young people with epilepsy.
Epilepsia. 2021 Jul 18. doi: 10.1111/epi.17006.
PubMed Abstract available

CONTENTO M, Pizzo F, Lopez-Madrona VJ, Lagarde S, et al
Changes in epileptogenicity biomarkers after stereotactic thermocoagulation.
Epilepsia. 2021 Jul 17. doi: 10.1111/epi.16989.
PubMed Abstract available

SAINJU RK, Dragon DN, Winnike HB, Ten Eyck P, et al
Hypercapnic ventilatory response in epilepsy patients treated with VNS: A case-control study.
Epilepsia. 2021 Jul 15. doi: 10.1111/epi.16997.
PubMed Abstract available

LEE CH, Le JT, Swann JW
Brain state-dependent high-frequency activity as a biomarker for abnormal neocortical networks in an epileptic spasms animal model.
Epilepsia. 2021 Jul 13. doi: 10.1111/epi.17008.
PubMed Abstract available

AMIN U, Primiani CT, MacIver S, Rivera-Cruz A, et al
Value of smartphone videos for diagnosis of seizures: Everyone owns half an epilepsy monitoring unit.
Epilepsia. 2021 Jul 13. doi: 10.1111/epi.17001.
PubMed Abstract available

GAINZA-LEIN M, Barcia Aguilar C, Piantino J, Chapman KE, et al
Factors associated with long-term outcomes in pediatric refractory status epilepticus.
Epilepsia. 2021 Jul 12. doi: 10.1111/epi.16984.
PubMed Abstract available

WHITNEY DG, Caird MS, Hurvitz EA, Rajapakse CS, et al
Effect of levetiracetam and oxcarbazepine on 4-year fragility fracture risk among prepubertal and pubertal children with epilepsy.
Epilepsia. 2021 Jul 12. doi: 10.1111/epi.16998.
PubMed Abstract available

JOSEPHSON CB, Engbers JDT, Sajobi TT, Wahby S, et al
Predicting postoperative epilepsy surgery satisfaction in adults using the 19-item Epilepsy Surgery Satisfaction Questionnaire and machine learning.
Epilepsia. 2021 Jul 9. doi: 10.1111/epi.16992.
PubMed Abstract available

HUSEIN N, Josephson CB, Keezer MR
Understanding cardiovascular disease in older adults with epilepsy.
Epilepsia. 2021 Jul 9. doi: 10.1111/epi.16991.
PubMed Abstract available

MANNINEN E, Chary K, Lapinlampi N, Andrade P, et al
Acute thalamic damage as a prognostic biomarker for post-traumatic epileptogenesis.
Epilepsia. 2021 Jul 9. doi: 10.1111/epi.16986.
PubMed Abstract available

LATTANZI S, Giovannini G, Brigo F, Orlandi N, et al
Clinical phenotypes within nonconvulsive status epilepticus.
Epilepsia. 2021 Jul 9. doi: 10.1111/epi.16999.
PubMed Abstract available

VERRIER RL, Pang TD, Nearing BD, Schachter SC, et al
Epileptic heart: A clinical syndromic approach.
Epilepsia. 2021 Jul 8. doi: 10.1111/epi.16966.
PubMed Abstract available

NEHLIG A, Sperling MR
An interview with Shruthi Iyer, 2021 Epilepsia Prize Winner for Basic Science Research.
Epilepsia. 2021 Jul 7. doi: 10.1111/epi.16985.
PubMed

SPERLING MR, Nehlig A
An interview with Christian Meisel, 2021 Epilepsia Prize Winner for Clinical Research.
Epilepsia. 2021 Jul 7. doi: 10.1111/epi.16988.
PubMed

SIMEONE KA, Wilke JC, Matthews SA, Simeone TA, et al
Ketogenic diet-mediated seizure reduction preserves CA1 cell numbers in epileptic Kcna1-null mice: An unbiased stereological assessment.
Epilepsia. 2021 Jul 7. doi: 10.1111/epi.16983.
PubMed Abstract available

SHELLHAAS RA, Wusthoff CJ, Numis AL, Chu CJ, et al
Early-life epilepsy after acute symptomatic neonatal seizures: A prospective multicenter study.
Epilepsia. 2021 Jul 2. doi: 10.1111/epi.16978.
PubMed Abstract available

BARKER-HALISKI M, Knox K, Zierath D, Koneval Z, et al
Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital.
Epilepsia. 2021;62:1677-1688.
PubMed Abstract available

QURAISHI IH, Hirsch LJ
Patient-detectable responsive neurostimulation as a seizure warning system.
Epilepsia. 2021;62:e110-e116.
PubMed Abstract available

CHOI HS, Ko A, Kim SH, Lee ST, et al
Disparate treatment outcomes according to presence of pathogenic mutations in West syndrome.
Epilepsia. 2021;62:1656-1664.
PubMed Abstract available

DEVINSKY O, King L, Schwartz D, Conway E, et al
Effect of fenfluramine on convulsive seizures in CDKL5 deficiency disorder.
Epilepsia. 2021;62:e98-e102.
PubMed Abstract available

June 2021

HAN FY, Conboy-Schmidt L, Rybachuk G, Volk HA, et al
Dietary medium chain triglycerides for management of epilepsy: New data from human, dog, and rodent studies.
Epilepsia. 2021 Jun 25. doi: 10.1111/epi.16972.
PubMed Abstract available

ISMAIL FS, Faustmann PM
Experimental investigations of antiepileptic drugs in astrocytes-microglia co-cultures suggest possible protective effects on astrocytes during early epileptogenesis.
Epilepsia. 2021 Jun 24. doi: 10.1111/epi.16968.
PubMed

KUMAR U, Li L, Bragin A, Engel J Jr, et al
Spike and wave discharges and fast ripples during posttraumatic epileptogenesis.
Epilepsia. 2021 Jun 21. doi: 10.1111/epi.16958.
PubMed Abstract available

CORNET MC, Morabito V, Lederer D, Glass HC, et al
Neonatal presentation of genetic epilepsies: Early differentiation from acute provoked seizures.
Epilepsia. 2021 Jun 21. doi: 10.1111/epi.16957.
PubMed Abstract available

HUNTER MB, Chin RFM
Impaired social attention detected through eye movements in children with early-onset epilepsy.
Epilepsia. 2021 Jun 17. doi: 10.1111/epi.16962.
PubMed Abstract available

DI NUNZIO M, Di Sapia R, Sorrentino D, Kebede V, et al
Microglia proliferation plays distinct roles in acquired epilepsy depending on disease stages.
Epilepsia. 2021 Jun 15. doi: 10.1111/epi.16956.
PubMed Abstract available

ROTH J, Constantini S, Ekstein M, Weiner HL, et al
Epilepsy surgery in infants up to 3 months of age: Safety, feasibility, and outcomes: A multicenter, multinational study.
Epilepsia. 2021 Jun 14. doi: 10.1111/epi.16959.
PubMed Abstract available

SCULIER C, Barcia Aguilar C, Gaspard N, Gainza-Lein M, et al
Clinical presentation of new onset refractory status epilepticus in children (the pSERG cohort).
Epilepsia. 2021 Jun 6. doi: 10.1111/epi.16950.
PubMed Abstract available

TARIGHATI RASEKHI R, Devlin KN, Mass JA, Donmez M, et al
Improving prediction of sudden unexpected death in epilepsy: From SUDEP-7 to SUDEP-3.
Epilepsia. 2021 Jun 4. doi: 10.1111/epi.16928.
PubMed Abstract available

OTTOSSON NE, Silvera Ejneby M, Wu X, Estrada-Mondragon A, et al
Synthetic resin acid derivatives selectively open the hKV 7.2/7.3 channel and prevent epileptic seizures.
Epilepsia. 2021 Jun 4. doi: 10.1111/epi.16932.
PubMed Abstract available

FITZGERALD MP, Kaufman MC, Massey SL, Fridinger S, et al
Assessing seizure burden in pediatric epilepsy using an electronic medical record-based tool through a common data element approach.
Epilepsia. 2021 Jun 2. doi: 10.1111/epi.16934.
PubMed Abstract available

LEWIS-SMITH D, Galer PD, Balagura G, Kearney H, et al
Modeling seizures in the Human Phenotype Ontology according to contemporary ILAE concepts makes big phenotypic data tractable.
Epilepsia. 2021;62:1293-1305.
PubMed Abstract available

SOMANI A, El-Hachami H, Patodia S, Sisodiya S, et al
Regional microglial populations in central autonomic brain regions in SUDEP.
Epilepsia. 2021;62:1318-1328.
PubMed Abstract available

May 2021

LAM J, DuBois JM, Rowley J, Rousset OG, et al
In vivo hippocampal cornu ammonis 1-3 glutamatergic abnormalities are associated with temporal lobe epilepsy surgery outcomes.
Epilepsia. 2021 May 31. doi: 10.1111/epi.16952.
PubMed Abstract available

PATEL S, Grinspoon R, Fleming B, Skirvin LA, et al
The long-term efficacy of cannabidiol in the treatment of refractory epilepsy.
Epilepsia. 2021 May 29. doi: 10.1111/epi.16936.
PubMed Abstract available

LEE-LANE E, Torabi F, Lacey A, Fonferko-Shadrach B, et al
Epilepsy, antiepileptic drugs, and the risk of major cardiovascular events.
Epilepsia. 2021 May 27. doi: 10.1111/epi.16930.
PubMed Abstract available

ERNST ME, Baugh EH, Thomas A, Bier L, et al
CSNK2B: A broad spectrum of neurodevelopmental disability and epilepsy severity.
Epilepsia. 2021 May 26. doi: 10.1111/epi.16931.
PubMed Abstract available

ALESSI N, Perucca P, McIntosh AM
Missed, mistaken, stalled: Identifying components of delay to diagnosis in epilepsy.
Epilepsia. 2021 May 20. doi: 10.1111/epi.16929.
PubMed Abstract available

STEVELINK R, Luykx JJ, Lin BD, Leu C, et al
Shared genetic basis between genetic generalized epilepsy and background electroencephalographic oscillations.
Epilepsia. 2021 May 18. doi: 10.1111/epi.16922.
PubMed Abstract available

PERNICI CD, Mensah JA, Dahle EJ, Johnson KJ, et al
Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program.
Epilepsia. 2021 May 17. doi: 10.1111/epi.16925.
PubMed Abstract available

VELISKOVA J, Marra C, Liu Y, Shekhar A, et al
Early onset epilepsy and sudden unexpected death in epilepsy with cardiac arrhythmia in mice carrying the early infantile epileptic encephalopathy 47 gain-of-function FHF1(FGF12) missense mutation.
Epilepsia. 2021 May 13. doi: 10.1111/epi.16916.
PubMed Abstract available

MODI AC, Guilfoyle SM, Glauser TA, Mara CA, et al
Supporting treatment adherence regimens in children with epilepsy: A randomized clinical trial.
Epilepsia. 2021 May 12. doi: 10.1111/epi.16921.
PubMed Abstract available

SHIVACHARAN RS, Chiang CC, Wei X, Subramanian M, et al
Neural recruitment by ephaptic coupling in epilepsy.
Epilepsia. 2021 May 12. doi: 10.1111/epi.16903.
PubMed Abstract available

DEJAKAISAYA H, Kwan P, Jones NC
Astrocyte and glutamate involvement in the pathogenesis of epilepsy in Alzheimer's disease.
Epilepsia. 2021 May 10. doi: 10.1111/epi.16918.
PubMed Abstract available

BAXENDALE SA, Thompson PJ
The clinical utility of a memory specialization index in epilepsy surgery patients with unilateral hippocampal sclerosis.
Epilepsia. 2021 May 10. doi: 10.1111/epi.16919.
PubMed Abstract available

WU Z, Deshpande T, Henning L, Bedner P, et al
Cell death of hippocampal CA1 astrocytes during early epileptogenesis.
Epilepsia. 2021 May 6. doi: 10.1111/epi.16910.
PubMed Abstract available

TROSCHER AR, Sakaraki E, Mair KM, Kock U, et al
T cell numbers correlate with neuronal loss rather than with seizure activity in medial temporal lobe epilepsy.
Epilepsia. 2021 May 6. doi: 10.1111/epi.16914.
PubMed Abstract available

HE H, Guzman RE, Cao D, Sierra-Marquez J, et al
The molecular and phenotypic spectrum of CLCN4-related epilepsy.
Epilepsia. 2021 May 5. doi: 10.1111/epi.16906.
PubMed Abstract available

ONG C, Damisah EC, Gruenbaum SE, Dhaher R, et al
Increased branched-chain amino acids at baseline and hours before a spontaneous seizure in the human epileptic brain.
Epilepsia. 2021 May 5. doi: 10.1111/epi.16920.
PubMed Abstract available

SEGAL EB, Tarquinio D, Miller I, Wheless JW, et al
Evaluation of diazepam nasal spray in patients with epilepsy concomitantly using maintenance benzodiazepines: An interim subgroup analysis from a phase 3, long-term, open-label safety study.
Epilepsia. 2021 May 4. doi: 10.1111/epi.16901.
PubMed Abstract available

TSALOUCHIDOU PE, Mintziras I, Biermann L, Krause K, et al
Temporal encephaloceles in epilepsy patients and asymptomatic cases: Size may indicate epileptogenicity.
Epilepsia. 2021 May 3. doi: 10.1111/epi.16900.
PubMed Abstract available

BERGIN P, Langan Y, Beghi E, Donner E, et al
Invitation to participate in a prospective case-control study of sudden unexpected death in epilepsy.
Epilepsia. 2021;62:1280-1281.
PubMed

THOMSON KE, West PJ, Metcalf CS, Wilcox KS, et al
Response: Usefulness of the post-kainate spontaneous recurrent seizure model for screening for antiseizure and for neuroprotective effects.
Epilepsia. 2021;62:1290.
PubMed

QUIGG M, Broshek DK, Bertram EH 3rd
The unclear interhemispheric modulation of mood: A response to Doherty et al. on predicting mood decline following temporal lobe surgery in adults.
Epilepsia. 2021;62:1282.
PubMed

PRIVITERA M, Bhathal H, Wong M, Cross JH, et al
Time to onset of cannabidiol (CBD) treatment effect in Lennox-Gastaut syndrome: Analysis from two randomized controlled trials.
Epilepsia. 2021;62:1130-1140.
PubMed Abstract available

TEHRANI N, Wilson W, Pittman DJ, Mosher V, et al
Localization of interictal discharge origin: A simultaneous intracranial electroencephalographic-functional magnetic resonance imaging study.
Epilepsia. 2021;62:1105-1118.
PubMed Abstract available

WHITING AC, Morita-Sherman M, Li M, Vegh D, et al
Automated analysis of cortical volume loss predicts seizure outcomes after frontal lobectomy.
Epilepsia. 2021;62:1074-1084.
PubMed Abstract available

DEUTSCHOVA B, Klimes P, Jordan Z, Jurak P, et al
Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus.
Epilepsia. 2021;62:e70-e75.
PubMed Abstract available

GRUENBAUM BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, et al
Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality.
Epilepsia. 2021;62:1041-1056.
PubMed Abstract available

WEIL AG, Lewis EC, Ibrahim GM, Kola O, et al
Hemispherectomy Outcome Prediction Scale: Development and validation of a seizure freedom prediction tool.
Epilepsia. 2021;62:1064-1073.
PubMed Abstract available

KANG JY, Pickard AA, Bronder J, Yenokyan G, et al
Magnetic resonance-guided laser interstitial thermal therapy: Correlations with seizure outcome.
Epilepsia. 2021;62:1085-1091.
PubMed Abstract available

April 2021

SUZUKI T, Koike Y, Ashikawa K, Otomo N, et al
Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
Epilepsia. 2021 Apr 29. doi: 10.1111/epi.16911.
PubMed Abstract available

SCALA M, Efthymiou S, Sultan T, De Waele J, et al
Homozygous SCN1B variants causing early infantile epileptic encephalopathy 52 affect voltage-gated sodium channel function.
Epilepsia. 2021 Apr 26. doi: 10.1111/epi.16913.
PubMed Abstract available

MAZARATI A, Medel-Matus JS, Shin D, Jacobs JP, et al
Disruption of intestinal barrier and endotoxemia after traumatic brain injury: Implications for post-traumatic epilepsy.
Epilepsia. 2021 Apr 23. doi: 10.1111/epi.16909.
PubMed Abstract available

MENDES COELHO VC, Morita-Sherman M, Yasuda CL, Alvim MMK, et al
Magnetic resonance imaging findings and clinical characteristics in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy in a predominantly adult cohort.
Epilepsia. 2021 Apr 22. doi: 10.1111/epi.16907.
PubMed Abstract available

HAMDI H, Albader F, Spatola G, Laguitton V, et al
Long-term cognitive outcome after radiosurgery in epileptic hypothalamic hamartomas and review of the literature.
Epilepsia. 2021 Apr 20. doi: 10.1111/epi.16896.
PubMed Abstract available

ZINCHUK M, Kustov G, Pashnin E, Pochigaeva K, et al
Interictal dysphoric disorder in people with and without epilepsy.
Epilepsia. 2021 Apr 15. doi: 10.1111/epi.16902.
PubMed Abstract available

SALANOVA V, Sperling MR, Gross RE, Irwin CP, et al
The SANTE study at 10 years of follow-up: Effectiveness, safety, and sudden unexpected death in epilepsy.
Epilepsia. 2021 Apr 8. doi: 10.1111/epi.16895.
PubMed Abstract available

DOYLE GA, Reiner BC, Crist RC, Rao AM, et al
Investigation of long interspersed element-1 retrotransposons as potential risk factors for idiopathic temporal lobe epilepsy.
Epilepsia. 2021 Apr 7. doi: 10.1111/epi.16897.
PubMed Abstract available

BOUX F, Forbes F, Collomb N, Zub E, et al
Neurovascular multiparametric MRI defines epileptogenic and seizure propagation regions in experimental mesiotemporal lobe epilepsy.
Epilepsia. 2021 Apr 5. doi: 10.1111/epi.16886.
PubMed Abstract available

WANG M, Zhang Z, Liu D, Xie W, et al
Educational attainment protects against epilepsy independent of cognitive function: A Mendelian randomization study.
Epilepsia. 2021 Apr 5. doi: 10.1111/epi.16894.
PubMed Abstract available

NAKAMURA J, Sorge ST, Winawer MR, Phelan JC, et al
Reproductive decision-making in families containing multiple individuals with epilepsy.
Epilepsia. 2021 Apr 4. doi: 10.1111/epi.16889.
PubMed Abstract available

Diverse genetic causes of polymicrogyria with epilepsy.
Epilepsia. 2021;62:973-983.
PubMed Abstract available

LOSCHER W, Kaila K
Reply to the commentary by Ben-Ari and Delpire: Bumetanide and neonatal seizures: Fiction versus reality.
Epilepsia. 2021;62:941-946.
PubMed Abstract available

BERTUCCELLI M, Verheyen K, Hallemans A, Sander JW, et al
Deconstructing Dravet syndrome neurocognitive development: A scoping review.
Epilepsia. 2021;62:874-887.
PubMed Abstract available

DAVID B, Kroll-Seger J, Schuch F, Wagner J, et al
External validation of automated focal cortical dysplasia detection using morphometric analysis.
Epilepsia. 2021;62:1005-1021.
PubMed Abstract available

THIRUNAVU V, Du R, Wu JY, Berg AT, et al
The role of surgery in the management of Lennox-Gastaut syndrome: A systematic review and meta-analysis of the clinical evidence.
Epilepsia. 2021;62:888-907.
PubMed Abstract available

JOHNSON M, Samudra N, Gallagher MJ, Abou-Khalil B, et al
Near SUDEP during bilateral stereo-EEG monitoring characterized by diffuse postictal EEG suppression.
Epilepsia. 2021;62:e60-e64.
PubMed Abstract available

BEN-ARI Y, Delpire E
Phenobarbital, midazolam, bumetanide, and neonatal seizures: The devil is in the details.
Epilepsia. 2021;62:935-940.
PubMed Abstract available

March 2021

SHELLHAAS RA
Neonatal seizures reach the mainstream: The ILAE classification of seizures in the neonate.
Epilepsia. 2021;62:629-631.
PubMed

VAZQUEZ B, Tomson T, Dobrinsky C, Schuck E, et al
Perampanel and pregnancy.
Epilepsia. 2021;62:698-708.
PubMed Abstract available

HAROWITZ J, Crandall L, McGuone D, Devinsky O, et al
Seizure-related deaths in children: The expanding spectrum.
Epilepsia. 2021;62:570-582.
PubMed Abstract available

HONYBUN E, Thwaites R, Malpas CB, Rayner G, et al
Prenatal valproate exposure and adverse neurodevelopmental outcomes: Does sex matter?
Epilepsia. 2021;62:709-719.
PubMed Abstract available

DE CURTIS M, Garbelli R, Uva L
A hypothesis for the role of axon demyelination in seizure generation.
Epilepsia. 2021;62:583-595.
PubMed Abstract available

JOSEPHSON CB, Wiebe S
Precision Medicine: Academic dreaming or clinical reality?
Epilepsia. 2021;62 Suppl 2:S78-S89.
PubMed Abstract available

SISODIYA SM
Precision medicine and therapies of the future.
Epilepsia. 2021;62 Suppl 2:S90-S105.
PubMed Abstract available

February 2021

COUSYN L, Navarro V, Chavez M
Preictal state detection using prodromal symptoms: A machine learning approach.
Epilepsia. 2021;62:e42-e47.
PubMed Abstract available

SANCHEZ FERNANDEZ I, Amengual-Gual M, Gainza-Lein M, Barcia Aguilar C, et al
Cost-effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms.
Epilepsia. 2021;62:347-357.
PubMed Abstract available

WANG HT, Zhu ZA, Li YY, Lou SS, et al
CDKL5 deficiency in forebrain glutamatergic neurons results in recurrent spontaneous seizures.
Epilepsia. 2021;62:517-528.
PubMed Abstract available

PAYNE DE, Dell KL, Karoly PJ, Kremen V, et al
Identifying seizure risk factors: A comparison of sleep, weather, and temporal features using a Bayesian forecast.
Epilepsia. 2021;62:371-382.
PubMed Abstract available

January 2021

DEMERATH T, Urbach H
Apples and oranges.
Epilepsia. 2021;62:279-280.
PubMed

WANG I, Jones SE
In response: Apples and oranges.
Epilepsia. 2021;62:281.
PubMed

BENICZKY S, Rampp S, Asadi-Pooya AA, Rubboli G, et al
Optimal choice of antiseizure medication: Agreement among experts and validation of a web-based decision support application.
Epilepsia. 2021;62:220-227.
PubMed Abstract available

WAGNER RG, Norstrom F, Bertram MY, Tollman S, et al
Community health workers to improve adherence to anti-seizure medication in rural South Africa: Is it cost-effective?
Epilepsia. 2021;62:98-106.
PubMed Abstract available

KIM LH, Parker JJ, Ho AL, Feng AY, et al
Contemporaneous evaluation of patient experience, surgical strategy, and seizure outcomes in patients undergoing stereoelectroencephalography or subdural electrode monitoring.
Epilepsia. 2021;62:74-84.
PubMed Abstract available

MYERS KA, Bennett MF, Hildebrand MS, Coleman MJ, et al
Transcriptome analysis of a ring chromosome 20 patient cohort.
Epilepsia. 2021;62:e22-e28.
PubMed Abstract available

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