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  Epilepsy

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Articles published in J Neurosci

Retrieve available abstracts of 39 articles:
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Single Articles


    November 2024
  1. QUE Z, Olivero-Acosta MI, Robinson M, Chen I, et al
    Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutation.
    J Neurosci. 2024 Nov 18:e2027232024. doi: 10.1523/JNEUROSCI.2027-23.2024.
    PubMed     Abstract available


  2. ZHAO C, Liu Y, Zeng J, Luo X, et al
    Spatiotemporal Neural Network for Sublexical Information Processing: An Intracranial SEEG Study.
    J Neurosci. 2024;44:e0717242024.
    PubMed     Abstract available


    July 2024
  3. WANG K, Xie F, Liu C, Wang G, et al
    Chinese verbal fluency deficiency in temporal lobe epilepsy with and without hippocampal sclerosis: a multiscale study.
    J Neurosci. 2024 Jul 25:e0558242024. doi: 10.1523/JNEUROSCI.0558-24.2024.
    PubMed     Abstract available


    April 2024
  4. LIEBERGALL SR, Goldberg EM
    Ndnf Interneuron Excitability Is Spared in a Mouse Model of Dravet Syndrome.
    J Neurosci. 2024;44:e1977232024.
    PubMed     Abstract available


  5. KIM JH, Chen W, Chao ES, Rivera A, et al
    GABAergic/Glycinergic and Glutamatergic Neurons Mediate Distinct Neurodevelopmental Phenotypes of STXBP1 Encephalopathy.
    J Neurosci. 2024;44:e1806232024.
    PubMed     Abstract available


    March 2024
  6. IRAVANI B, Kaboodvand N, Stieger JR, Liang EY, et al
    Intracranial Recordings of the Human Orbitofrontal Cortical Activity during Self-Referential Episodic and Valenced Self-Judgments.
    J Neurosci. 2024;44:e1634232024.
    PubMed     Abstract available


    December 2023
  7. MAO M, Mattei C, Rollo B, Byars S, et al
    Distinctive in vitro phenotypes in iPSC-derived neurons from patients with gain- and loss-of-function SCN2A developmental and epileptic encephalopathy.
    J Neurosci. 2023 Dec 26:JN-RM-0692-23. doi: 10.1523/JNEUROSCI.0692-23.2023.
    PubMed     Abstract available


  8. MILLEVERT C, Vidas-Guscic N, Vanherp L, Jonckers E, et al
    Resting-State Functional MRI and PET Imaging as Noninvasive Tools to Study (Ab)Normal Neurodevelopment in Humans and Rodents.
    J Neurosci. 2023;43:8275-8293.
    PubMed     Abstract available


  9. CHANCEY JH, Ahmed AA, Guillen FI, Ghatpande V, et al
    Complex Synaptic and Intrinsic Interactions Disrupt Input/Output Functions in the Hippocampus of Scn1b Knock-Out Mice.
    J Neurosci. 2023;43:8562-8577.
    PubMed     Abstract available


    November 2023
  10. VIEIRA MM, Peng S, Won S, Hong E, et al
    A frameshift variant of GluN2A identified in an epilepsy patient results in NMDA receptor mistargeting.
    J Neurosci. 2023 Nov 30:JN-RM-0557-23. doi: 10.1523/JNEUROSCI.0557-23.2023.
    PubMed     Abstract available


  11. WANG SH, Siebenhuhner F, Arnulfo G, Myrov V, et al
    Critical-like Brain Dynamics in a Continuum from Second- to First-Order Phase Transition.
    J Neurosci. 2023;43:7642-7656.
    PubMed     Abstract available


    October 2023
  12. EXTREMET J, Ramirez-Franco J, Fronzaroli-Molinieres L, Boumedine-Guignon N, et al
    Rescue of normal excitability in LGI1-deficient epileptic neurons.
    J Neurosci. 2023 Oct 20:JN-RM-0701-23. doi: 10.1523/JNEUROSCI.0701-23.2023.
    PubMed     Abstract available


    September 2023
  13. OJEDA VALENCIA G, Gregg NM, Huang H, Lundstrom BN, et al
    Signatures of Electrical Stimulation Driven Network Interactions in the Human Limbic System.
    J Neurosci. 2023;43:6697-6711.
    PubMed     Abstract available


    August 2023
  14. WHITEBIRCH AC, Santoro B, Barnett A, Lisgaras CP, et al
    Reduced cholecystokinin-expressing interneuron input contributes to disinhibition of the hippocampal CA2 region in a mouse model of temporal lobe epilepsy.
    J Neurosci. 2023 Aug 25:JN-RM-2091-22. doi: 10.1523/JNEUROSCI.2091-22.2023.
    PubMed     Abstract available


  15. CLAWSON W, Waked B, Madec T, Ghestem A, et al
    Perturbed information processing complexity in experimental epilepsy.
    J Neurosci. 2023 Aug 7:JN-RM-0383-23. doi: 10.1523/JNEUROSCI.0383-23.2023.
    PubMed     Abstract available


  16. YAO AY, Halloran PJ, Ge Y, Singh N, et al
    Bace1 deletion in the adult reverses epileptiform activity and sleep-wake disturbances in AD mice.
    J Neurosci. 2023 Aug 3:JN-RM-2124-22. doi: 10.1523/JNEUROSCI.2124-22.2023.
    PubMed     Abstract available


    July 2023
  17. TERAN FA, Sainju RK, Bravo E, Wagnon J, et al
    Seizures Cause Prolonged Impairment of Ventilation, CO(2) Chemoreception and Thermoregulation.
    J Neurosci. 2023;43:4959-4971.
    PubMed     Abstract available


    June 2023
  18. TOBIN WF, Weston MC
    Distinct features of interictal activity predict seizure localization and burden in a mouse model of childhood epilepsy.
    J Neurosci. 2023 Jun 8:JN-RM-2205-22. doi: 10.1523/JNEUROSCI.2205-22.2023.
    PubMed     Abstract available


    May 2023
  19. BURROWS DRW, Diana G, Pimpel B, Moeller F, et al
    Microscale Neuronal Activity Collectively Drives Chaotic and Inflexible Dynamics at the Macroscale in Seizures.
    J Neurosci. 2023;43:3259-3283.
    PubMed     Abstract available


    March 2023
  20. SCALMANI P, Paterra R, Mantegazza M, Avoli M, et al
    Involvement of GABAergic Interneuron Subtypes in 4-Aminopyridine-Induced Seizure-Like Events in Mouse Entorhinal Cortex in Vitro.
    J Neurosci. 2023;43:1987-2001.
    PubMed     Abstract available


    February 2023
  21. ZHAO D, Pinares-Garcia P, McKenzie CE, Bleakley LE, et al
    Retinal Dysfunction in a Mouse Model of HCN1 Genetic Epilepsy.
    J Neurosci. 2023 Feb 22:JN-RM-1615-22. doi: 10.1523/JNEUROSCI.1615-22.2022.
    PubMed     Abstract available


  22. KONTAXI C, Ivanova D, Davenport EC, Kind PC, et al
    Epilepsy-related CDKL5 deficiency slows synaptic vesicle endocytosis in central nerve terminals.
    J Neurosci. 2023 Feb 9:JN-RM-1537-22. doi: 10.1523/JNEUROSCI.1537-22.2023.
    PubMed     Abstract available


  23. CULLEN ER, Tariq K, Shore AN, Luikart BW, et al
    mTORC2 Inhibition Improves Morphological Effects of PTEN Loss, But Does Not Correct Synaptic Dysfunction or Prevent Seizures.
    J Neurosci. 2023;43:827-845.
    PubMed     Abstract available


    January 2023
  24. RYNER RF, Derera ID, Armbruster M, Kansara A, et al
    Cortical Parvalbumin-Positive Interneuron Development and Function Are Altered in the APC Conditional Knockout Mouse Model of Infantile and Epileptic Spasms Syndrome.
    J Neurosci. 2023 Jan 30:JN-RM-0572-22. doi: 10.1523/JNEUROSCI.0572-22.2022.
    PubMed     Abstract available


    December 2022
  25. COLANGELI R, Morena M, Werner A, Thompson RJ, et al
    2-AG-mediated Control of GABAergic Signaling is Impaired in a Model of Epilepsy.
    J Neurosci. 2022 Dec 1:JN-RM-0541-22. doi: 10.1523/JNEUROSCI.0541-22.2022.
    PubMed     Abstract available


    August 2022
  26. KANG YJ, Lee SH, Boychuk JA, Butler CR, et al
    Adult Born Dentate Granule Cell Mediated Upregulation of Feedback Inhibition in a Mouse Model of Traumatic Brain Injury.
    J Neurosci. 2022 Aug 24. pii: JNEUROSCI.2263-21.2022.
    PubMed     Abstract available


  27. BUCKMASTER PS, Reyes B, Kahn T, Wyeth M, et al
    Ventral hippocampal formation is the primary epileptogenic zone in a rat model of temporal lobe epilepsy.
    J Neurosci. 2022 Aug 19. pii: JNEUROSCI.0429-22.2022.
    PubMed     Abstract available


    June 2022
  28. TIWARI MN, Mohan S, Biala Y, Shor O, et al
    Corticotropin releasing factor mediates KCa3.1 inhibition, hyperexcitability and seizures in acquired epilepsy.
    J Neurosci. 2022 Jun 21. pii: JNEUROSCI.2475-21.2022.
    PubMed     Abstract available


    March 2022
  29. SUGIURA H, Shimada T, Moriya-Ito K, Goto JI, et al
    A Farnesyltransferase Inhibitor Restores Cognitive Deficits in Tsc2 (+/-) Mice through Inhibition of Rheb1.
    J Neurosci. 2022;42:2598-2612.
    PubMed     Abstract available


    February 2022
  30. BUTLER CR, Westbrook GL, Schnell E
    Adaptive mossy cell circuit plasticity after status epilepticus.
    J Neurosci. 2022 Feb 17. pii: JNEUROSCI.1008-21.2022.
    PubMed     Abstract available


    December 2021
  31. STRENG ML, Tetzlaff MR, Krook-Magnuson E
    Distinct Fastigial Output Channels and Their Impact on Temporal Lobe Seizures.
    J Neurosci. 2021;41:10091-10107.
    PubMed     Abstract available


    November 2021
  32. PESCOSOLIDO MF, Ouyang Q, Liu JS, Morrow EM, et al
    Loss of Christianson Syndrome Na(+)/H(+) Exchanger 6 (NHE6) Causes Abnormal Endosome Maturation and Trafficking Underlying Lysosome Dysfunction in Neurons.
    J Neurosci. 2021;41:9235-9256.
    PubMed     Abstract available


    October 2021
  33. QUE Z, Olivero-Acosta MI, Zhang J, Eaton M, et al
    Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1.2-L1342P genetic variant.
    J Neurosci. 2021 Oct 28. pii: JNEUROSCI.0564-21.2021.
    PubMed     Abstract available


  34. HAO S, Wang Q, Tang B, Wu Z, et al
    CDKL5 Deficiency Augments Inhibitory Input into the Dentate Gyrus That Can Be Reversed by Deep Brain Stimulation.
    J Neurosci. 2021;41:9031-9046.
    PubMed     Abstract available


  35. MADAR AD, Pfammatter JA, Bordenave J, Plumley EI, et al
    Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy.
    J Neurosci. 2021 Oct 6. pii: JNEUROSCI.2439-20.2021.
    PubMed     Abstract available


  36. DAS A, Menon V
    Asymmetric Frequency-Specific Feedforward and Feedback Information Flow between Hippocampus and Prefrontal Cortex during Verbal Memory Encoding and Recall.
    J Neurosci. 2021;41:8427-8440.
    PubMed     Abstract available


  37. CALIN A, Ilie AS, Akerman CJ
    Disrupting epileptiform activity by preventing parvalbumin interneuron depolarization block.
    J Neurosci. 2021 Oct 5. pii: JNEUROSCI.1002-20.2021.
    PubMed     Abstract available


    September 2021
  38. ERATA E, Gao Y, Purkey AM, Soderblom EJ, et al
    Cnksr2 loss in mice leads to increased neural activity and behavioral phenotypes of Epilepsy-Aphasia Syndrome.
    J Neurosci. 2021 Sep 27. pii: JNEUROSCI.0650-21.2021.
    PubMed     Abstract available


  39. WENGERT ER, Miralles RM, Wedgwood KCA, Wagley PK, et al
    Somatostatin-positive Interneurons Contribute to Seizures in SCN8A Epileptic Encephalopathy.
    J Neurosci. 2021 Sep 17. pii: JNEUROSCI.0718-21.2021.
    PubMed     Abstract available


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