Retrieve available abstracts of 29 articles: HTML format
Single Articles
April 2025
PANG Y, Li H, Chen X, Cao Y, et al A phase I, single-center, randomized, open-label, three-period crossover study to
evaluate the drug-drug interaction between ZSP1273 and oseltamivir in healthy
Chinese subjects.
Antimicrob Agents Chemother. 2025;69:e0172924. PubMedAbstract available
March 2025
ZHAO L, Li C, Wang M, Zhou M, et al Potent antiviral activity of simnotrelvir against key epidemic SARS-CoV-2
variants with a high resistance barrier.
Antimicrob Agents Chemother. 2025 Mar 10:e0155624. doi: 10.1128/aac.01556. PubMedAbstract available
February 2025
RODRIGUEZ L, Lee HW, Li J, Martin R, et al SARS-CoV-2 resistance analyses from the Phase 3 PINETREE study of remdesivir
treatment in nonhospitalized participants.
Antimicrob Agents Chemother. 2025;69:e0123824. PubMedAbstract available
December 2024
MENDES S, Guimaraes LC, Costa PAC, Fernandez CC, et al Intranasal liposomal angiotensin-(1-7) administration reduces inflammation and
viral load in the lungs during SARS-CoV-2 infection in K18-hACE2 transgenic mice.
Antimicrob Agents Chemother. 2024;68:e0083524. PubMedAbstract available
November 2024
ZHANG M, Lian X, Gao Y, Jiang L, et al LDC000067, a CDK9 inhibitor, unveils promising results in suppressing influenza
virus infections in vitro and in vivo.
Antimicrob Agents Chemother. 2024 Nov 20:e0117224. doi: 10.1128/aac.01172. PubMedAbstract available
October 2024
CARLIN AF, Beadle JR, Ardanuy J, Clark AE, et al Oral pharmacokinetics and efficacy of oral phospholipid remdesivir nucleoside
prodrugs against SARS-CoV-2 in mice.
Antimicrob Agents Chemother. 2024;68:e0103924. PubMedAbstract available
MIYASHITA N, Nakamori Y, Ogata M, Fukuda N, et al Efficacy of ensitrelvir for cough due to COVID-19 Omicron variant in medical
healthcare workers.
Antimicrob Agents Chemother. 2024;68:e0106424. PubMedAbstract available
September 2024
FAGHIHI I, Yan VC Clinical pharmacodynamics of obeldesivir versus remdesivir.
Antimicrob Agents Chemother. 2024;68:e0096924. PubMed
POLI ANR, Tietjen I, Nandwana NK, Cassel J, et al Design of novel and highly selective SARS-CoV-2 main protease inhibitors.
Antimicrob Agents Chemother. 2024 Sep 3:e0056224. doi: 10.1128/aac.00562. PubMedAbstract available
August 2024
FAGHIHI I, Yan VC Remdesivir treatment does not reduce viral titers in patients with COVID-19.
Antimicrob Agents Chemother. 2024;68:e0085624. PubMedAbstract available
SALOMEZ-IHL C, Giai J, Barbado M, Paris A, et al H(2) inhalation therapy in patients with moderate COVID-19 (H(2)COVID): a
prospective ascending-dose phase I clinical trial.
Antimicrob Agents Chemother. 2024;68:e0057324. PubMedAbstract available
June 2024
SHIN JS, Jang Y, Kim D-S, Jung E, et al Inhibition of endocytic uptake of severe acute respiratory syndrome coronavirus 2
and endo-lysosomal acidification by diphenoxylate.
Antimicrob Agents Chemother. 2024;68:e0034124. PubMedAbstract available
May 2024
CLEGG LE, Stepanov O, Schmidt H, Tang W, et al Accelerating therapeutics development during a pandemic: population
pharmacokinetics of the long-acting antibody combination AZD7442
(tixagevimab/cilgavimab) in the prophylaxis and treatment of COVID-19.
Antimicrob Agents Chemother. 2024;68:e0158723. PubMedAbstract available
April 2024
CHESNOKOV A, Ivashchenko AA, Matsuzaki Y, Takashita E, et al Influenza C virus susceptibility to antivirals with different mechanisms of
action.
Antimicrob Agents Chemother. 2024 Apr 8:e0172723. doi: 10.1128/aac.01727. PubMedAbstract available
XU S, Esmaeili S, Cardozo-Ojeda EF, Goyal A, et al Two-way pharmacodynamic modeling of drug combinations and its application to
pairs of repurposed Ebola and SARS-CoV-2 agents.
Antimicrob Agents Chemother. 2024;68:e0101523. PubMedAbstract available
TANG W-F, Chang Y-H, Lin C-C, Jheng J-R, et al BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits
SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in
combination with remdesivir.
Antimicrob Agents Chemother. 2024;68:e0095623. PubMedAbstract available
March 2024
YU Y, Chen S, Zhang H, Duan Y, et al A panel of janus kinase inhibitors identified with anti-inflammatory effects
protect mice from lethal influenza virus infection.
Antimicrob Agents Chemother. 2024 Mar 12:e0135023. doi: 10.1128/aac.01350. PubMedAbstract available
MIAH M, Davis AM, Hannoun C, Said JS, et al Identification of epidermal growth factor receptor-tyrosine kinase inhibitor
targeting the VP1 pocket of human rhinovirus.
Antimicrob Agents Chemother. 2024;68:e0106423. PubMedAbstract available
ZHANG R, Zhou J, Yan H, Liu X, et al Manidipine is not a potential inhibitor against SARS-CoV-2 main protease.
Antimicrob Agents Chemother. 2024;68:e0129723. PubMed
February 2024
PLOTNIK D, Sager JE, Aryal M, Fanget MC, et al A phase 1 study in healthy volunteers to investigate the safety, tolerability,
and pharmacokinetics of VIR-2482: a monoclonal antibody for the prevention of
severe influenza A illness.
Antimicrob Agents Chemother. 2024 Feb 20:e0127323. doi: 10.1128/aac.01273. PubMedAbstract available
January 2024
YANG H, Yu X, Hou W, Liu X, et al Effectiveness and safety of nirmatrelvir-ritonavir in kidney transplant
recipients with severe kidney dysfunction infected with COVID-19.
Antimicrob Agents Chemother. 2024 Jan 30:e0138423. doi: 10.1128/aac.01384. PubMedAbstract available
BAKER J, Ombredane H, Daly L, Knowles I, et al Pan-antiviral effects of a PIKfyve inhibitor on respiratory virus infection in
human nasal epithelium and mice.
Antimicrob Agents Chemother. 2024;68:e0105023. PubMedAbstract available
STRIZKI JM, Gaspar JM, Howe JA, Hutchins B, et al Molnupiravir maintains antiviral activity against SARS-CoV-2 variants and
exhibits a high barrier to the development of resistance.
Antimicrob Agents Chemother. 2024;68:e0095323. PubMedAbstract available
December 2023
ZHANG H, Zhou J, Chen H, Mao J, et al Phase I study, and dosing regimen selection for a pivotal COVID-19 trial of
GST-HG171.
Antimicrob Agents Chemother. 2023 Dec 15:e0111523. doi: 10.1128/aac.01115. PubMedAbstract available
November 2023
TONG X, Keung W, Arnold LD, Stevens LJ, et al Evaluation of in vitro antiviral activity of SARS-CoV-2 M(pro) inhibitor
pomotrelvir and cross-resistance to nirmatrelvir resistance substitutions.
Antimicrob Agents Chemother. 2023;67:e0084023. PubMedAbstract available
July 2023
PALOMINO-CABRERA R, Tejerina F, Molero-Salinas A, Ferris M, et al Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic
Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab.
Antimicrob Agents Chemother. 2023;67:e0026623. PubMedAbstract available
April 2023
DE LEON P, Canas-Arranz R, Bustos MJ, Saiz M, et al Inhibition of Human Coronaviruses by Combinations of Host-Targeted and
Direct-Acting Antivirals.
Antimicrob Agents Chemother. 2023;67:e0170322. PubMedAbstract available
March 2023
ZHANG D, Zhao Y, You X, He S, et al Repurposing Axl Kinase Inhibitors for the Treatment of Respiratory Syncytial
Virus Infection.
Antimicrob Agents Chemother. 2023;67:e0148722. PubMedAbstract available
LIU STH, Mirceta M, Lin G, Anderson DM, et al Safety, Tolerability, and Pharmacokinetics of Anti-SARS-CoV-2 Immunoglobulin
Intravenous (Human) Investigational Product (COVID-HIGIV) in Healthy Adults: a
Randomized, Controlled, Double-Blinded, Phase 1 Study.
Antimicrob Agents Chemother. 2023;67:e0151422. PubMedAbstract available