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COVID-19: Daily Top 10 Papers


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Articles published in Antiviral Res

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    March 2021
  1. ROOSENHOFF R, Schutten M, Reed V, Clinch B, et al
    Secondary substitutions in the hemagglutinin and neuraminidase genes associated with neuraminidase inhibitor resistance are rare in the Influenza Resistance Information Study (IRIS).
    Antiviral Res. 2021 Mar 10:105060. doi: 10.1016/j.antiviral.2021.105060.
    PubMed     Abstract available


    February 2021
  2. PATEL MC, Chesnokov A, Jones J, Mishin VP, et al
    Susceptibility of widely diverse influenza a viruses to PB2 polymerase inhibitor pimodivir.
    Antiviral Res. 2021;188:105035.
    PubMed     Abstract available


  3. HIDEKAZU OSADA, Chon I, Phyu WW, Wagatsuma K, et al
    Development of cycling probe based real-time PCR methodology for influenza A viruses possessing the PA/I38T amino acid substitution associated with reduced baloxavir susceptibility.
    Antiviral Res. 2021 Feb 9:105036. doi: 10.1016/j.antiviral.2021.105036.
    PubMed     Abstract available


  4. MARTIN R, Li J, Parvangada A, Perry J, et al
    Genetic Conservation of SARS-CoV-2 RNA Replication Complex in Globally Circulating Isolates and Recently Emerged Variants from Humans and Minks Suggests Minimal Pre-Existing Resistance to Remdesivir.
    Antiviral Res. 2021 Feb 4:105033. doi: 10.1016/j.antiviral.2021.105033.
    PubMed     Abstract available


    January 2021
  5. LIU C, Boland S, Scholle MD, Bardiot D, et al
    Dual Inhibition of SARS-CoV-2 and Human Rhinovirus with Protease Inhibitors in Clinical Development.
    Antiviral Res. 2021 Jan 27:105020. doi: 10.1016/j.antiviral.2021.105020.
    PubMed     Abstract available


  6. ZHU Q, Zhang Y, Wang L, Yao X, et al
    Inhibition of coronavirus infection by a synthetic STING agonist in primary human airway system.
    Antiviral Res. 2021 Jan 11:105015. doi: 10.1016/j.antiviral.2021.105015.
    PubMed     Abstract available


  7. DU R, Cheng H, Cui Q, Peet NP, et al
    Identification of a novel inhibitor targeting influenza A virus group 2 hemagglutinins.
    Antiviral Res. 2021;186:105013.
    PubMed     Abstract available


    November 2020
  8. SVENNINGSEN EB, Thyrsted J, Blay-Cadanet J, Liu H, et al
    Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro.
    Antiviral Res. 2020 Nov 25:104988. doi: 10.1016/j.antiviral.2020.104988.
    PubMed     Abstract available


  9. ZHANG Y, Song W, Chen S, Yuan Z, et al
    A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2.
    Antiviral Res. 2020 Nov 17:104974. doi: 10.1016/j.antiviral.2020.104974.
    PubMed     Abstract available


  10. HEJDANEK J, Radilova K, Pachl P, Hodek J, et al
    Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.
    Antiviral Res. 2020 Nov 6:104971. doi: 10.1016/j.antiviral.2020.104971.
    PubMed     Abstract available


  11. ZARAKET H, Hurt AC, Clinch B, Barr I, et al
    Burden of influenza B virus infection and considerations for clinical management.
    Antiviral Res. 2020 Nov 4:104970. doi: 10.1016/j.antiviral.2020.104970.
    PubMed     Abstract available


    October 2020
  12. CHOI SW, Shin JS, Park SJ, Jung E, et al
    Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes.
    Antiviral Res. 2020 Oct 19:104955. doi: 10.1016/j.antiviral.2020.104955.
    PubMed     Abstract available


    September 2020
  13. SAITO R, Osada H, Wagatsuma K, Chon I, et al
    Duration of fever and symptoms in children after treatment with baloxavir marboxil and oseltamivir during the 2018-2019 season and detection of variant influenza a viruses with polymerase acidic subunit substitutions.
    Antiviral Res. 2020;183:104951.
    PubMed     Abstract available


  14. ZHU Q, Hu H, Liu H, Shen H, et al
    A synthetic STING agonist inhibits the replication of Human Parainfluenza Virus 3 and Rhinovirus 16 through distinct mechanisms.
    Antiviral Res. 2020 Sep 16:104933. doi: 10.1016/j.antiviral.2020.104933.
    PubMed     Abstract available


  15. THEERAWATANASIRIKUL S, Kuo CJ, Phecharat N, Chootip J, et al
    Structural-based virtual screening and in vitro assays for small molecules inhibiting the feline coronavirus 3CL protease as a surrogate platform for coronaviruses.
    Antiviral Res. 2020 Sep 7:104927. doi: 10.1016/j.antiviral.2020.104927.
    PubMed     Abstract available


  16. GURARD-LEVIN ZA, Liu C, Jekle A, Jaisinghani R, et al
    Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry.
    Antiviral Res. 2020 Sep 4:104924. doi: 10.1016/j.antiviral.2020.104924.
    PubMed     Abstract available


    August 2020
  17. PATEL MC, Mishin VP, De La Cruz JA, Chesnokov A, et al
    Detection of baloxavir resistant influenza A viruses using next generation sequencing and pyrosequencing methods.
    Antiviral Res. 2020 Aug 13:104906. doi: 10.1016/j.antiviral.2020.104906.
    PubMed     Abstract available


  18. LI W, Li J, Sun M, Yang L, et al
    Viperin protein inhibits the replication of caprine parainfluenza virus 3 (CPIV 3) by interaction with viral N protein.
    Antiviral Res. 2020 Aug 12:104903. doi: 10.1016/j.antiviral.2020.104903.
    PubMed     Abstract available


  19. KONKOLOVA E, Dejmek M, Hrebabecky H, Sala M, et al
    Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses.
    Antiviral Res. 2020 Aug 4:104899. doi: 10.1016/j.antiviral.2020.104899.
    PubMed     Abstract available


  20. MOHR PG, Williams J, Tashiro M, Streltsov VA, et al
    Substitutions at H134 and in the 430-loop region in influenza B neuraminidases can confer reduced susceptibility to multiple neuraminidase inhibitors.
    Antiviral Res. 2020 Aug 1:104895. doi: 10.1016/j.antiviral.2020.104895.
    PubMed     Abstract available


  21. BIALY D, Shelton H
    Functional neuraminidase inhibitor resistance motifs in avian influenza A(H5Nx) viruses.
    Antiviral Res. 2020 Aug 1:104886. doi: 10.1016/j.antiviral.2020.104886.
    PubMed     Abstract available


    July 2020
  22. OKAMOTO M, Toyama M, Baba M
    The chemokine receptor antagonist cenicriviroc inhibits the replication of SARS-CoV-2 in vitro.
    Antiviral Res. 2020 Jul 30:104902. doi: 10.1016/j.antiviral.2020.104902.
    PubMed     Abstract available


  23. CONZELMANN C, Gilg A, Gross R, Schutz D, et al
    An enzyme-based immunodetection assay to quantify SARS-CoV-2 infection.
    Antiviral Res. 2020 Jul 29:104882. doi: 10.1016/j.antiviral.2020.104882.
    PubMed     Abstract available


  24. CAI W, Wen H, Zhou Q, Wu L, et al
    14-Deoxy-11,12-didehydroandrographolide inhibits apoptosis in influenza A(H5N1) virus-infected human lung epithelial cells via the caspase-9-dependent intrinsic apoptotic pathway which contributes to its antiviral activity.
    Antiviral Res. 2020 Jul 20:104885. doi: 10.1016/j.antiviral.2020.104885.
    PubMed     Abstract available


  25. GALLIAN P, Pastorino B, Morel P, Chiaroni J, et al
    Lower prevalence of antibodies neutralizing SARS-CoV-2 in group O French blood donors.
    Antiviral Res. 2020 Jul 14:104880. doi: 10.1016/j.antiviral.2020.104880.
    PubMed     Abstract available


  26. PIZZORNO A, Padey B, Dubois J, Julien T, et al
    In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2.
    Antiviral Res. 2020 Jul 14:104878. doi: 10.1016/j.antiviral.2020.104878.
    PubMed     Abstract available


  27. VENISSE N, Peytavin G, Bouchet S, Gagnieu MC, et al
    Concerns about pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) studies in the new therapeutic area of COVID-19 infection.
    Antiviral Res. 2020 Jul 10:104866. doi: 10.1016/j.antiviral.2020.104866.
    PubMed     Abstract available


  28. PAN X, Zhou P, Fan T, Wu Y, et al
    Immunoglobulin fragment F(ab')2 against RBD potently neutralizes SARS-CoV-2 in vitro.
    Antiviral Res. 2020 Jul 10:104868. doi: 10.1016/j.antiviral.2020.104868.
    PubMed     Abstract available


  29. KIM SY, Jin W, Sood A, Montgomery DW, et al
    Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions.
    Antiviral Res. 2020 Jul 9:104873. doi: 10.1016/j.antiviral.2020.104873.
    PubMed     Abstract available


  30. SALINAS FM, Nebreda AD, Vazquez L, Gentilini MV, et al
    Imiquimod suppresses respiratory syncytial virus (RSV) replication via PKA pathway and reduces RSV induced-inflammation and viral load in mice lungs.
    Antiviral Res. 2020;179:104817.
    PubMed     Abstract available


    June 2020
  31. MATYUSHENKO V, Kotomina T, Kudryavtsev I, Mezhenskaya D, et al
    Conserved T-cell epitopes of respiratory syncytial virus (RSV) delivered by recombinant live attenuated influenza vaccine viruses efficiently induce RSV-specific lung-localized memory T cells and augment influenza-specific resident memory T-cell respo
    Antiviral Res. 2020 Jun 22:104864. doi: 10.1016/j.antiviral.2020.104864.
    PubMed     Abstract available


  32. TAKASHITA E, Abe T, Morita H, Nagata S, et al
    Influenza A(H1N1)pdm09 virus exhibiting reduced susceptibility to baloxavir due to a PA E23K substitution detected from a child without baloxavir treatment.
    Antiviral Res. 2020 Jun 20:104828. doi: 10.1016/j.antiviral.2020.104828.
    PubMed     Abstract available


  33. JOCKUSCH S, Tao C, Li X, Anderson TK, et al
    A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19.
    Antiviral Res. 2020;180:104857.
    PubMed     Abstract available


  34. TILMANIS D, Koszalka P, Barr IG, Rossignol JF, et al
    Host-targeted Nitazoxanide has a high barrier to resistance but does not reduce the emergence or proliferation of oseltamivir-resistant influenza viruses in vitro or in vivo when used in combination with oseltamivir.
    Antiviral Res. 2020 Jun 13:104851. doi: 10.1016/j.antiviral.2020.104851.
    PubMed     Abstract available


  35. SHANNON A, Le NT, Selisko B, Eydoux C, et al
    Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites.
    Antiviral Res. 2020;178:104793.
    PubMed     Abstract available


    May 2020
  36. TAI W, Zhang X, He Y, Jiang S, et al
    Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2.
    Antiviral Res. 2020 May 13:104820. doi: 10.1016/j.antiviral.2020.104820.
    PubMed     Abstract available


  37. BLOCKUS S, Sake SM, Wetzke M, Grethe C, et al
    Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry.
    Antiviral Res. 2020;177:104774.
    PubMed     Abstract available


    April 2020
  38. MANTLO E, Bukreyeva N, Maruyama J, Paessler S, et al
    Antiviral activities of type I interferons to SARS-CoV-2 infection.
    Antiviral Res. 2020;179:104811.
    PubMed     Abstract available


  39. ABED Y, Fage C, Checkmahomed L, Venable MC, et al
    Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice.
    Antiviral Res. 2020 Apr 25:104807. doi: 10.1016/j.antiviral.2020.104807.
    PubMed     Abstract available


  40. BRAY M, Rayner C, Noel F, Jans D, et al
    Ivermectin and COVID-19: a report in Antiviral Research, widespread interest, an FDA warning, two letters to the editor and the authors' responses.
    Antiviral Res. 2020 Apr 21:104805. doi: 10.1016/j.antiviral.2020.104805.
    PubMed    


  41. LAURE M, Hamza H, Koch-Heier J, Quernheim M, et al
    Antiviral efficacy against Influenza virus and pharmacokinetic analysis of a novel MEK-inhibitor, ATR-002, in cell culture and in the mouse model.
    Antiviral Res. 2020 Apr 15:104806. doi: 10.1016/j.antiviral.2020.104806.
    PubMed     Abstract available


  42. SALLARD E, Lescure FX, Yazdanpanah Y, Mentre F, et al
    Type 1 interferons as a potential treatment against COVID-19.
    Antiviral Res. 2020;178:104791.
    PubMed     Abstract available


  43. SUZUKI S, Shichinohe S, Itoh Y, Nakayama M, et al
    Low replicative fitness of neuraminidase inhibitor-resistant H7N9 avian influenza A virus with R292K substitution in neuraminidase in cynomolgus macaques compared with I222T substitution.
    Antiviral Res. 2020 Apr 6:104790. doi: 10.1016/j.antiviral.2020.104790.
    PubMed     Abstract available


  44. TANG T, Bidon M, Jaimes JA, Whittaker GR, et al
    Coronavirus membrane fusion mechanism offers as a potential target for antiviral development.
    Antiviral Res. 2020 Apr 6:104792. doi: 10.1016/j.antiviral.2020.104792.
    PubMed     Abstract available


  45. CALY L, Druce JD, Catton MG, Jans DA, et al
    The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro.
    Antiviral Res. 2020 Apr 3:104787. doi: 10.1016/j.antiviral.2020.104787.
    PubMed     Abstract available


  46. CHOY KT, Yin-Lam Wong A, Kaewpreedee P, Sia SF, et al
    Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro.
    Antiviral Res. 2020 Apr 3:104786. doi: 10.1016/j.antiviral.2020.104786.
    PubMed     Abstract available


    March 2020
  47. SOLDEVILA N, Toledo D, Ortiz de Lejarazu R, Tamames S, et al
    Effect of antiviral treatment in older patients hospitalized with confirmed influenza.
    Antiviral Res. 2020 Mar 29:104785. doi: 10.1016/j.antiviral.2020.104785.
    PubMed     Abstract available


  48. JALILY PH, Duncan MC, Fedida D, Wang J, et al
    Put a cork in it: Plugging the M2 viral ion channel to sink influenza.
    Antiviral Res. 2020 Mar 27:104780. doi: 10.1016/j.antiviral.2020.104780.
    PubMed     Abstract available


  49. HUSSEIN AFA, Cheng H, Tundup S, Antanasijevic A, et al
    Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus.
    Antiviral Res. 2020 Mar 25:104782. doi: 10.1016/j.antiviral.2020.104782.
    PubMed     Abstract available


  50. SLOAN SE, Szretter KJ, Sundaresh B, Narayan KM, et al
    Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study.
    Antiviral Res. 2020 Mar 6:104763. doi: 10.1016/j.antiviral.2020.104763.
    PubMed     Abstract available


  51. TOURET F, de Lamballerie X
    Of chloroquine and COVID-19.
    Antiviral Res. 2020;177:104762.
    PubMed     Abstract available


  52. SIGRIST C, Bridge A, Le Mercier P
    A potential role for integrins in host cell entry by SARS-CoV-2.
    Antiviral Res. 2020 Mar 1:104759. doi: 10.1016/j.antiviral.2020.104759.
    PubMed    


    February 2020
  53. QIU H, Andersen H, Tarbet EB, Muhammad FS, et al
    Efficacy of anti-influenza immunoglobulin (FLU-IGIV) in ferrets and mice infected with 2009 pandemic influenza virus.
    Antiviral Res. 2020 Feb 27:104753. doi: 10.1016/j.antiviral.2020.104753.
    PubMed     Abstract available


  54. KUMARI R, Guo Z, Kumar A, Wiens M, et al
    Influenza virus NS1- C/EBPbeta gene regulatory complex inhibits RIG-I transcription.
    Antiviral Res. 2020 Feb 21:104747. doi: 10.1016/j.antiviral.2020.104747.
    PubMed     Abstract available


  55. MIFSUD EJ, Tilmanis D, Oh DY, Ming-Kay Tai C, et al
    Prophylaxis of ferrets with nitazoxanide and oseltamivir combinations is more effective at reducing the impact of influenza a virus infection compared to oseltamivir monotherapy.
    Antiviral Res. 2020 Feb 20:104751. doi: 10.1016/j.antiviral.2020.104751.
    PubMed     Abstract available


    January 2020
  56. TAKASHITA E, Daniels RS, Fujisaki S, Gregory V, et al
    Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2017-2018.
    Antiviral Res. 2020 Jan 28:104718. doi: 10.1016/j.antiviral.2020.104718.
    PubMed     Abstract available


    November 2019
  57. PASCUA PNQ, Marathe BM, Bisen S, Webby RJ, et al
    Influenza B viruses from different genetic backgrounds are variably impaired by neuraminidase inhibitor resistance-associated substitutions.
    Antiviral Res. 2019 Nov 29:104669. doi: 10.1016/j.antiviral.2019.104669.
    PubMed     Abstract available


    August 2019
  58. BAVAGNOLI L, Campanini G, Forte M, Ceccotti G, et al
    Identification of a novel antiviral micro-RNA targeting the NS1 protein of the H1N1 pandemic human influenza virus and a corresponding viral escape mutation.
    Antiviral Res. 2019 Aug 27:104593. doi: 10.1016/j.antiviral.2019.104593.
    PubMed     Abstract available


  59. ARIKATA M, Itoh Y, Shichinohe S, Nakayama M, et al
    Efficacy of clarithromycin against H5N1 and H7N9 avian influenza a virus infection in cynomolgus monkeys.
    Antiviral Res. 2019 Aug 14:104591. doi: 10.1016/j.antiviral.2019.104591.
    PubMed     Abstract available


    July 2019
  60. NG K, Raheem J, St Laurent CD, Marcet CT, et al
    Responses of human mast cells and epithelial cells following exposure to influenza A virus.
    Antiviral Res. 2019 Jul 23:104566. doi: 10.1016/j.antiviral.2019.104566.
    PubMed     Abstract available


  61. LI J, Yang Y, Wang M, Ren X, et al
    Rapid isolation of a potent human antibody against H7N9 influenza virus from an infected patient.
    Antiviral Res. 2019;170:104564.
    PubMed     Abstract available


  62. ABED Y, Fage C, Checkmahomed L, Begin G, et al
    The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors.
    Antiviral Res. 2019 Jul 16:104561. doi: 10.1016/j.antiviral.2019.104561.
    PubMed     Abstract available


  63. SEDEYN K, Saelens X
    New antibody-based prevention and treatment options for influenza.
    Antiviral Res. 2019 Jul 16:104562. doi: 10.1016/j.antiviral.2019.104562.
    PubMed     Abstract available


    June 2019
  64. MIFSUD EJ, Hayden FG, Hurt AC
    Antivirals targeting the polymerase complex of influenza viruses.
    Antiviral Res. 2019 Jun 24:104545. doi: 10.1016/j.antiviral.2019.104545.
    PubMed     Abstract available


  65. MCKIMM-BRESCHKIN JL, Barrett S, McKenzie-Kludas C, McAuley J, et al
    Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant.
    Antiviral Res. 2019;169:104542.
    PubMed     Abstract available


  66. ADAMS SE, Lee N, Lugovtsev VY, Kan A, et al
    Effect of influenza H1N1 neuraminidase V116A and I117V mutations on NA activity and sensitivity to NA inhibitors.
    Antiviral Res. 2019;169:104539.
    PubMed     Abstract available


  67. ARTARINI A, Meyer M, Shin YJ, Huber K, et al
    Regulation of influenza a virus mRNA splicing by CLK1.
    Antiviral Res. 2019 Jun 6. pii: S0166-3542(18)30668.
    PubMed     Abstract available


    May 2019
  68. FARRUKEE R, Butler J, Reading PC, Hurt AC, et al
    Characterization of substitutions in the neuraminidase of A(H7N9) influenza viruses selected following serial passage in the presence of different neuraminidase inhibitors.
    Antiviral Res. 2019 May 24. pii: S0166-3542(18)30673.
    PubMed     Abstract available


  69. GEORGEL AF, Cayet D, Pizzorno A, Rosa-Calatrava M, et al
    Toll-like receptor 5 agonist flagellin reduces Influenza A Virus replication independently of type I interferon and interleukin 22 and improves antiviral efficacy of oseltamivir.
    Antiviral Res. 2019 May 9. pii: S0166-3542(18)30570.
    PubMed     Abstract available


  70. KOTOMINA T, Isakova-Sivak I, Matyushenko V, Kim KH, et al
    Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease.
    Antiviral Res. 2019 May 7. pii: S0166-3542(19)30121.
    PubMed     Abstract available


    April 2019
  71. CHIBANGA VP, Dirr L, Guillon P, El-Deeb IM, et al
    New antiviral approaches for human parainfluenza: Inhibiting the haemagglutinin-neuraminidase.
    Antiviral Res. 2019 Apr 2. pii: S0166-3542(18)30740.
    PubMed     Abstract available


  72. TARASOV SA, Zarubaev VV, Gorbunov EA, Sergeeva SA, et al
    Retraction notice to "Activity of ultra-low doses of antibodies to gamma-interferon against lethal influenza A(H1N1)2009 virus infection in mice" [Antiviral Research 93 (2012) 219-224].
    Antiviral Res. 2019;164:177.
    PubMed    


    March 2019
  73. NANNETTI G, Massari S, Mercorelli B, Bertagnin C, et al
    Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance.
    Antiviral Res. 2019 Mar 15. pii: S0166-3542(18)30659.
    PubMed     Abstract available


    February 2019
  74. KOSZALKA P, Tilmanis D, Roe M, Vijaykrishna D, et al
    Baloxavir marboxil susceptibility of influenza viruses from the Asia-Pacific, 2012-2018.
    Antiviral Res. 2019 Feb 13. pii: S0166-3542(18)30698.
    PubMed     Abstract available


  75. MOHL G, Liddle N, Nygaard J, Dorius A, et al
    Novel influenza inhibitors designed to target PB1 interactions with host importin RanBP5.
    Antiviral Res. 2019 Feb 8. pii: S0166-3542(18)30487.
    PubMed     Abstract available


  76. HONG JY, Chen TH, Chen YJ, Liu CC, et al
    Highly immunogenic influenza virus-like particles containing B-cell-activating factor (BAFF) for multi-subtype vaccine development.
    Antiviral Res. 2019;164:12-22.
    PubMed     Abstract available


  77. SCHOGLER A, Caliaro O, Brugger M, Oliveira Esteves BI, et al
    Modulation of the unfolded protein response pathway as an antiviral approach in airway epithelial cells.
    Antiviral Res. 2019;162:44-50.
    PubMed     Abstract available


    January 2019
  78. WATANABE A, Ishida T, Hirotsu N, Kawaguchi K, et al
    Baloxavir marboxil in Japanese patients with seasonal influenza: Dose response and virus type/subtype outcomes from a randomized phase 2 study.
    Antiviral Res. 2019;163:75-81.
    PubMed     Abstract available


  79. KIM MH, Kang JO, Kim JY, Jung HE, et al
    Single mucosal vaccination targeting nucleoprotein provides broad protection against two lineages of influenza B virus.
    Antiviral Res. 2019 Jan 9. pii: S0166-3542(18)30589.
    PubMed     Abstract available


  80. ZHANG K, Li C, Luo YS, Wen L, et al
    Establishment of a lethal aged mouse model of human respiratory syncytial virus infection.
    Antiviral Res. 2019;161:125-133.
    PubMed     Abstract available


    December 2018
  81. GARG R, Latimer L, Gomis S, Gerdts V, et al
    Maternal vaccination with a novel chimeric glycoprotein formulated with a polymer-based adjuvant provides protection from human parainfluenza virus type 3 in newborn lambs.
    Antiviral Res. 2018 Dec 11. pii: S0166-3542(18)30464.
    PubMed     Abstract available


    October 2018
  82. SONG L, Xiong D, Kang X, Jiao Y, et al
    The optimized fusion protein HA1-2-FliC big up tri, openD2D3 promotes mixed Th1/Th2 immune responses to influenza H7N9 with low induction of systemic proinflammatory cytokines in mice.
    Antiviral Res. 2018 Oct 30. pii: S0166-3542(18)30186.
    PubMed     Abstract available


  83. NOSHI T, Kitano M, Taniguchi K, Yamamoto A, et al
    In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.
    Antiviral Res. 2018 Oct 11. pii: S0166-3542(18)30363.
    PubMed     Abstract available


  84. PICHON M, Picard C, Simon B, Gaymard A, et al
    Clinical management and viral genomic diversity analysis of a child's influenza A(H1N1)pdm09 infection in the context of a severe combined immunodeficiency.
    Antiviral Res. 2018;160:1-9.
    PubMed     Abstract available


    September 2018
  85. ABED Y, Tu V, Carbonneau J, Checkmahomed L, et al
    Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models.
    Antiviral Res. 2018 Sep 13. pii: S0166-3542(18)30313.
    PubMed     Abstract available


  86. KOLPE A, Schepens B, Ye L, Staeheli P, et al
    Passively transferred M2e-specific monoclonal antibody reduces influenza A virus transmission in mice.
    Antiviral Res. 2018 Sep 1. pii: S0166-3542(18)30314.
    PubMed     Abstract available


    August 2018
  87. XIA C, Seo YJ, Studstill CJ, Vijayan M, et al
    Transient inhibition of sphingosine kinases confers protection to influenza A virus infected mice.
    Antiviral Res. 2018 Aug 17. pii: S0166-3542(18)30220.
    PubMed     Abstract available


  88. SOOD R, Kumar N, Bhatia S, Chanu KV, et al
    Neuraminidase inhibitors susceptibility profiles of highly pathogenic influenza A (H5N1) viruses isolated from avian species in India (2006-2015).
    Antiviral Res. 2018 Aug 17. pii: S0166-3542(18)30167.
    PubMed     Abstract available


  89. BRODSKAIA AV, Timin AS, Gorshkov AN, Muslimov AR, et al
    Inhibition of influenza A virus by mixed siRNAs, targeting the PA, NP, and NS genes, delivered by hybrid microcarriers.
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    July 2018
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    Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors and status of novel antivirals, 2016-2017.
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    MPL and CpG combination adjuvants promote homologous and heterosubtypic cross protection of inactivated split influenza virus vaccine.
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    May 2018
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    Innovation and trends in the development and approval of antiviral medicines: 1987-2017 and beyond.
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    Profiling the in vitro drug-resistance mechanism of influenza A viruses towards the AM2-S31N proton channel blockers.
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    The role of adjuvant immunomodulatory agents for treatment of severe influenza.
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    A recombinant H7N9 influenza vaccine with the H7 hemagglutinin transmembrane domain replaced by the H3 domain induces increased cross-reactive antibodies and improved interclade protection in mice.
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    The MEK-inhibitor CI-1040 displays a broad anti-influenza activity in vitro and provides a prolonged treatment window compared to standard of care in vivo.
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    November 2016
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    October 2016
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    February 2016
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