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Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Influenza

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07.04.2025

1 Ann Intern Med
2 Antimicrob Agents Chemother
1 Biochem Biophys Res Commun
1 Biochemistry
1 BMC Pediatr
2 Epidemiol Infect
1 J Exp Med
1 J Infect Dis
1 J Virol
1 MMWR Morb Mortal Wkly Rep
3 Pediatrics
2 PLoS Comput Biol
17 PLoS One
1 Proc Natl Acad Sci U S A
1 Vaccine
4 Virology


   Retrieve available abstracts of this week’s articles:
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Single Articles


    Ann Intern Med

  1. DACSO CC
    Coadministration of RSV + influenza or COVID-19 vaccines was noninferior to separate administration for immune responses in adults aged >/=50 y.
    Ann Intern Med. 2025 Apr 1. doi: 10.7326/ANNALS-25-00904.
    PubMed         Abstract available


    Antimicrob Agents Chemother

  2. PANG Y, Li H, Chen X, Cao Y, et al
    A phase I, single-center, randomized, open-label, three-period crossover study to evaluate the drug-drug interaction between ZSP1273 and oseltamivir in healthy Chinese subjects.
    Antimicrob Agents Chemother. 2025;69:e0172924.
    PubMed         Abstract available

  3. ZHAO L, Li C, Wang M, Zhou M, et al
    Potent antiviral activity of simnotrelvir against key epidemic SARS-CoV-2 variants with a high resistance barrier.
    Antimicrob Agents Chemother. 2025 Mar 10:e0155624. doi: 10.1128/aac.01556.
    PubMed         Abstract available


    Biochem Biophys Res Commun

  4. LIU HL, Lin S, Hung W, Chang DC, et al
    A novel replicase-mediated self-amplifying RNA amplification mechanism of the SARS-CoV-2 replication-transcription system.
    Biochem Biophys Res Commun. 2025;758:151654.
    PubMed         Abstract available


    Biochemistry

  5. E SANTO AA, Reis A, Pinheiro AA, da Costa PI, et al
    Design of Mimetic Antibodies Targeting the SARS-CoV-2 Spike Glycoprotein Based on the GB1 Domain: A Molecular Simulation and Experimental Study.
    Biochemistry. 2025;64:1541-1549.
    PubMed         Abstract available


    BMC Pediatr

  6. JAFARI N, Akbari H, Maghsoodi A, Sarbakhsh P, et al
    The attitude of the unvaccinated children's parents toward pediatric COVID-19 vaccination in Tabriz, Iran.
    BMC Pediatr. 2025;25:248.
    PubMed         Abstract available


    Epidemiol Infect

  7. MONGE S, Humphreys J, Nicolay N, Braeye T, et al
    Comparison of two methods for the estimation of COVID-19 vaccine effectiveness of the autumnal booster within the VEBIS-EHR network in 2022/23.
    Epidemiol Infect. 2025;153:e54.
    PubMed         Abstract available

  8. MIN KH, Kim JH, Gil JY, Park JH, et al
    Factors associated with carditis adverse events following SARS-COV-2-19 vaccination.
    Epidemiol Infect. 2025;153:e51.
    PubMed         Abstract available


    J Exp Med

  9. MADSEN A, Okba NMA, Pholcharee T, Matz HC, et al
    Identification of a seasonal influenza vaccine-induced broadly protective neuraminidase antibody.
    J Exp Med. 2025;222:e20241930.
    PubMed         Abstract available


    J Infect Dis

  10. FRUTOS AM, Tenforde MW, Sundaresan D, Naleway AL, et al
    Influenza-associated hospitalization rates by underlying conditions, 2016-17 to 2019-20: A retrospective cohort study.
    J Infect Dis. 2025 Mar 28:jiaf164. doi: 10.1093.
    PubMed         Abstract available


    J Virol

  11. XIAO X, Wang X, Xu F, Liang Y, et al
    Synergistic effects of PA (S184N) and PB2 (E627K) mutations on the increased pathogenicity of H3N2 canine influenza virus infections in mice and dogs.
    J Virol. 2025 Apr 4:e0198424. doi: 10.1128/jvi.01984.
    PubMed         Abstract available


    MMWR Morb Mortal Wkly Rep

  12. JOBE NB, Rose E, Winn AK, Goldstein L, et al
    Human Metapneumovirus Seasonality and Co-Circulation with Respiratory Syncytial Virus - United States, 2014-2024.
    MMWR Morb Mortal Wkly Rep. 2025;74:182-187.
    PubMed         Abstract available


    Pediatrics

  13. ROWE SL, Sullivan SG, Munoz FM, Coates MM, et al
    COVID-19 Vaccination During Pregnancy and Major Structural Birth Defects.
    Pediatrics. 2025 Mar 14:e2024069778. doi: 10.1542/peds.2024-069778.
    PubMed         Abstract available

  14. COLEY RL, Leer J, Lanteri L
    Trends in Mental and Behavioral Health Risks in Adolescents: 1999-2021.
    Pediatrics. 2025;155:e2024068774.
    PubMed         Abstract available

  15. DESILVA MB, Haapala J, Vazquez-Benitez G, Daley MF, et al
    COVID-19 and Completion of Select Routine Childhood Vaccinations.
    Pediatrics. 2025 Mar 26:e2024068244. doi: 10.1542/peds.2024-068244.
    PubMed         Abstract available


    PLoS Comput Biol

  16. VON HOENE E, Roess A, Kavak H, Anderson T, et al
    Synthetic population generation with public health characteristics for spatial agent-based models.
    PLoS Comput Biol. 2025;21:e1012439.
    PubMed         Abstract available

  17. WU L, Baker CM, Tierney N, Carville K, et al
    Quantifying the impact of contact tracing interview prioritisation strategies on disease transmission: A modelling study.
    PLoS Comput Biol. 2025;21:e1012906.
    PubMed         Abstract available


    PLoS One

  18. JOSEPH M, Li Q, Shin S
    Health diagnosis associated with COVID-19 death in the United States: A retrospective cohort study using electronic health records.
    PLoS One. 2025;20:e0319585.
    PubMed         Abstract available

  19. BAYOU FD, Getaneh FB, Asmare L, Endawkie A, et al
    Trend of home birth and its associated factors in Ethiopia during COVID-19 and social crisis (2019-2023).
    PLoS One. 2025;20:e0320859.
    PubMed         Abstract available

  20. BUGHIN J, Cincera M, Reykowska D, Zyszkiewicz M, et al
    The great divide between employees: Clustering employee "well-being" during a pandemic.
    PLoS One. 2025;20:e0294540.
    PubMed         Abstract available

  21. PARK H, Miyano S
    Computational network biology analysis revealed COVID-19 severity markers: Molecular interplay between HLA-II with CIITA.
    PLoS One. 2025;20:e0319205.
    PubMed         Abstract available

  22. YOON J, Kim S, Kwon CY, Kang JW, et al
    Kyungok-go for fatigue in patients with long COVID: Double-blind, randomized, multicenter, pilot clinical study protocol.
    PLoS One. 2025;20:e0319459.
    PubMed         Abstract available

  23. LESTARI BW, Saptiningrum E, Huria L, Fikri AR, et al
    Pre-treatment direct costs for people with tuberculosis during the COVID-19 pandemic in different healthcare settings in Bandung, Indonesia.
    PLoS One. 2025;20:e0320401.
    PubMed         Abstract available

  24. YAGIHASHI M, Sakuma A, Murakami M
    Psychotherapies and psychological support for individuals facing psychological distress during the COVID-19 pandemic: A scoping review.
    PLoS One. 2025;20:e0318192.
    PubMed         Abstract available

  25. CARMOLA LR, Roebling AD, Khosravi D, Langsjoen RM, et al
    Viral and host factors associated with SARS-CoV-2 disease severity in Georgia, USA.
    PLoS One. 2025;20:e0317972.
    PubMed         Abstract available

  26. LIU Y, She R, Xing J
    Analysis of University Students' Mental Health from the Perspective of Occupational Harmony.
    PLoS One. 2025;20:e0309490.
    PubMed         Abstract available

  27. GKEKAS A, Ronaldson SJ, Parker A, Torgerson DJ, et al
    Improving patient recruitment to randomised trials can be cost-effective: A case-study of dexamethasone from the RECOVERY trial.
    PLoS One. 2025;20:e0314593.
    PubMed         Abstract available

  28. SURACE A, Munroe C, Martinez P
    "My drinking was way worse during the pandemic": A qualitative analysis of contextual and individual factors impacting alcohol use during the COVID-19 pandemic.
    PLoS One. 2025;20:e0319977.
    PubMed         Abstract available

  29. AIZAWA T
    Socio-economic gradients in hypertension and diabetes management amid the COVID-19 pandemic in India.
    PLoS One. 2025;20:e0315867.
    PubMed         Abstract available

  30. TAO Z, Ramasamy SS, Naktnasukanjn N, Ying F, et al
    Assessing competitiveness and complementarity in agricultural trade between China and Cambodia pre-pandemic and post-pandemic.
    PLoS One. 2025;20:e0321081.
    PubMed         Abstract available

  31. TREPTOW M, Bartels C, Ruhleder M, Kratzenberg A, et al
    Divergent psychological stress response patterns to the COVID-19 pandemic in psychiatric patients with vs. without PTSD: A real-world exploratory study.
    PLoS One. 2025;20:e0318839.
    PubMed         Abstract available

  32. STUKAS S, Goshua G, Conway EM, Lee AYY, et al
    ABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patients.
    PLoS One. 2025;20:e0320251.
    PubMed         Abstract available

  33. AWASTHI S, Dehkharghani MZ, Fudolig M
    Emergence to dominance: Estimating time to dominance of SARS-CoV-2 variants using nonlinear statistical models.
    PLoS One. 2025;20:e0311459.
    PubMed         Abstract available

  34. MITCHELL E, Are EB, Colijn C, Earn DJD, et al
    Using artificial intelligence tools to automate data extraction for living evidence syntheses.
    PLoS One. 2025;20:e0320151.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  35. GUAY B, Marghetis T, Wong C, Landy D, et al
    Quirks of cognition explain why we dramatically overestimate the size of minority groups.
    Proc Natl Acad Sci U S A. 2025;122:e2413064122.
    PubMed         Abstract available


    Vaccine

  36. OTORBAEVA D, Akmatova R, Cooley KM, Iwamoto C, et al
    Post-introduction evaluation (PIE) of the seasonal influenza vaccination program in Kyrgyzstan in 2023.
    Vaccine. 2025;55:127052.
    PubMed         Abstract available


    Virology

  37. ISHIGAKI H, Itoh Y
    Translational research on pandemic virus infection using nonhuman primate models.
    Virology. 2025;606:110511.
    PubMed         Abstract available

  38. BANGA NDZOUBOUKOU JL, Kamara AA, Ullah N, Lei Q, et al
    A meta-analysis on the immunogenicity of prototype, monovalent-adapted and bivalent vaccines against SARS-CoV-2 wildtype, Omicron BA.1 and Omicron BA.4/5 in healthy adults.
    Virology. 2025;606:110509.
    PubMed         Abstract available

  39. DAS SARMA J
    Murine beta-coronavirus spike protein: A major determinant of neuropathogenic properties.
    Virology. 2025;606:110499.
    PubMed         Abstract available

  40. LUNDRIGAN E, Uguccioni S, Hum C, Ahmed N, et al
    SARS-CoV-2 Nsp13 helicase modulates miR-146a-mediated signaling pathways.
    Virology. 2025;606:110493.
    PubMed         Abstract available


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