Home The Word Brain My Amedeo FAQ Privacy About Flying Publisher   


The daily Top 10 COVID papers


  Influenza

  Free Subscription


30.11.2020

8 Am J Med
4 Ann Intern Med
1 Antimicrob Agents Chemother
8 Cell
8 Epidemiol Infect
5 J Infect
1 J Infect Dis
1 J Virol
13 Lancet
3 Lancet Oncol
7 N Engl J Med
33 PLoS One
1 Proc Natl Acad Sci U S A
4 Vaccine


  Retrieve available abstracts of this week’s articles:
HTML format
 
 
Single Articles


    Am J Med

  1. DING D, Zhu C, Yao W
    A Cured Patient With 2019-nCoV Pneumonia.
    Am J Med. 2020;133:1291-1292.
    PubMed        

  2. PINETON DE CHAMBRUN M, Cohen-Aubart F, Donker DW, Cariou PL, et al
    SARS-CoV-2 Induces Acute and Refractory Relapse of Systemic Capillary Leak Syndrome (Clarkson's Disease).
    Am J Med. 2020;133:e663-e664.
    PubMed        

  3. SAWALHA AH
    Medical Licensure: It Is Time to Eliminate Practice Borders Within the United States.
    Am J Med. 2020;133:1120-1121.
    PubMed        

  4. GARRY DJ
    Successful Health Care Delivery Using Ambulatory Hospitals-Past, Present, and Future.
    Am J Med. 2020;133:e539-e540.
    PubMed        

  5. SCHATTNER A, Glick Y, Dubin I
    Coma During a Febrile Illness - Respiratory Syncytial Virus-Triggered Ischemic Stroke.
    Am J Med. 2020;133:e521-e523.
    PubMed        

  6. CHEN KL, Wang SJ, Chuang C, Huang LY, et al
    Novel Design for Door Handle-A Potential Technology to Reduce Hand Contamination in the COVID-19 Pandemic.
    Am J Med. 2020;133:1245-1246.
    PubMed        

  7. MASSOOMI MR, Anderson RD, Ahmed MM, Dasa O, et al
    Cardiovascular Considerations for the Internist and Hospitalist in the COVID-19 Era.
    Am J Med. 2020 Jul 9. pii: S0002-9343(20)30550.
    PubMed         Abstract available

  8. ALPERT JS, Juneman EB
    We Will Never Give Up.
    Am J Med. 2020;133:1111-1112.
    PubMed        


    Ann Intern Med

  9. MILLER DG, Pierson L, Doernberg S
    The Role of Medical Students During the COVID-19 Pandemic.
    Ann Intern Med. 2020;173:859.
    PubMed        

  10. RIVA MA, Paladino ME, Belingheri M
    The Role of Medical Students During the COVID-19 Pandemic.
    Ann Intern Med. 2020;173:858-859.
    PubMed        

  11. SORBELLO JG
    Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19.
    Ann Intern Med. 2020;173:860.
    PubMed        

  12. ROCHWERG B, Schunemann HJ, Akl EA
    Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19.
    Ann Intern Med. 2020;173:860.
    PubMed        


    Antimicrob Agents Chemother

  13. MCCULLOUGH PA
    Favipiravir and the Need for Early Ambulatory Treatment of SARS-CoV-2 Infection (COVID-19).
    Antimicrob Agents Chemother. 2020;64.
    PubMed         Abstract available


    Cell

  14. GRUBER CN, Patel RS, Trachtman R, Lepow L, et al
    Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C).
    Cell. 2020;183:982-995.
    PubMed         Abstract available

  15. DU S, Cao Y, Zhu Q, Yu P, et al
    Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
    Cell. 2020 Sep 14. pii: S0092-8674(20)31232-0. doi: 10.1016/j.cell.2020.
    PubMed         Abstract available

  16. CLAUSEN TM, Sandoval DR, Spliid CB, Pihl J, et al
    SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.
    Cell. 2020;183:1043-1057.
    PubMed         Abstract available

  17. CONSIGLIO CR, Cotugno N, Sardh F, Pou C, et al
    The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19.
    Cell. 2020;183:968-981.
    PubMed         Abstract available

  18. PICCOLI L, Park YJ, Tortorici MA, Czudnochowski N, et al
    Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
    Cell. 2020;183:1024-1042.
    PubMed         Abstract available

  19. RYDYZNSKI MODERBACHER C, Ramirez SI, Dan JM, Grifoni A, et al
    Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity.
    Cell. 2020;183:996-1012.
    PubMed         Abstract available

  20. LEIST SR, Dinnon KH 3rd, Schafer A, Tse LV, et al
    A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice.
    Cell. 2020;183:1070-1085.
    PubMed         Abstract available

  21. KREYE J, Reincke SM, Kornau HC, Sanchez-Sendin E, et al
    A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
    Cell. 2020;183:1058-1069.
    PubMed         Abstract available


    Epidemiol Infect

  22. DE SALAZAR PM, Gomez-Barroso D, Pampaka D, Gil JM, et al
    Lockdown measures and relative changes in the age-specific incidence of SARS-CoV-2 in Spain.
    Epidemiol Infect. 2020;148:e268.
    PubMed         Abstract available

  23. ZENG L, Wang S, Cai J, Sun S, et al
    Clinical characteristics of COVID-19 with cardiac injury: a systematic review and meta-analysis.
    Epidemiol Infect. 2020;148:e266.
    PubMed         Abstract available

  24. ZHANG SX, Graf-Vlachy L, Looi KH, Su R, et al
    Social media use as a predictor of handwashing during a pandemic: evidence from COVID-19 in Malaysia.
    Epidemiol Infect. 2020;148:e261.
    PubMed         Abstract available

  25. MAJUMDAR P, Niyogi S
    ORF3a mutation associated with higher mortality rate in SARS-CoV-2 infection.
    Epidemiol Infect. 2020;148:e262.
    PubMed         Abstract available

  26. RIVERA R, Rosenbaum JE, Quispe W
    Excess mortality in the United States during the first three months of the COVID-19 pandemic.
    Epidemiol Infect. 2020;148:e264.
    PubMed         Abstract available

  27. ISLAM MZ, Riaz BK, Islam ANMS, Khanam F, et al
    Risk factors associated with morbidity and mortality outcomes of COVID-19 patients on the 28th day of the disease course: a retrospective cohort study in Bangladesh.
    Epidemiol Infect. 2020;148:e263.
    PubMed         Abstract available

  28. GREBE G, Velez JA, Tiutiunnyk A, Aragon-Caqueo D, et al
    Dynamic quarantine: a comparative analysis of the Chilean public health response to COVID-19.
    Epidemiol Infect. 2020;148:e270.
    PubMed         Abstract available

  29. GURSAKAL N, Batmaz B, Aktuna G
    Drawing transmission graphs for COVID-19 in the perspective of network science.
    Epidemiol Infect. 2020;148:e269.
    PubMed         Abstract available


    J Infect

  30. MEYLAN S, Akrour R, Regina J, Bart PA, et al
    An Early Warning Score to predict ICU admission in COVID-19 positive patients.
    J Infect. 2020 May 28. pii: S0163-4453(20)30324.
    PubMed        

  31. BATISSE D, Benech N, Botelho-Nevers E, Bouiller K, et al
    Clinical recurrences of COVID-19 symptoms after recovery: viral relapse, reinfection or inflammatory rebound?
    J Infect. 2020 Jun 30. pii: S0163-4453(20)30454.
    PubMed         Abstract available

  32. DE LUSIGNAN S, Joy M, Oke J, McGagh D, et al
    Disparities in the excess risk of mortality in the first wave of COVID-19: cross sectional study of the English sentinel network.
    J Infect. 2020 Aug 25. pii: S0163-4453(20)30564.
    PubMed         Abstract available

  33. AXELL-HOUSE DB, Lavingia R, Rafferty M, Clark E, et al
    The Estimation of Diagnostic Accuracy of Tests for COVID-19: A Scoping Review.
    J Infect. 2020 Aug 31. pii: S0163-4453(20)30577.
    PubMed         Abstract available

  34. STANG A, Standl F, Kowall B, Brune B, et al
    Excess mortality due to COVID-19 in Germany.
    J Infect. 2020 Sep 19. pii: S0163-4453(20)30596.
    PubMed         Abstract available


    J Infect Dis

  35. CLEMENS EA, Holbrook BC, Kanekiyo M, Yewdell JW, et al
    An R848 conjugated influenza virus vaccine elicits robust IgG to hemagglutinin stem in a newborn nonhuman primate model.
    J Infect Dis. 2020 Nov 27. pii: 6007684. doi: 10.1093.
    PubMed         Abstract available


    J Virol

  36. BUSSE DC, Habgood-Coote D, Clare S, Brandt C, et al
    Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus.
    J Virol. 2020;94.
    PubMed         Abstract available


    Lancet

  37. FERIGATO S, Fernandez M, Amorim M, Ambrogi I, et al
    The Brazilian Government's mistakes in responding to the COVID-19 pandemic.
    Lancet. 2020 Oct 20. pii: S0140-6736(20)32164.
    PubMed        

  38. STEWART R, El-Harakeh A, Cherian SA
    Evidence synthesis communities in low-income and middle-income countries and the COVID-19 response.
    Lancet. 2020 Oct 20. pii: S0140-6736(20)32141.
    PubMed        

  39. PAES-SOUSA R, Millett C, Rocha R, Barreto ML, et al
    Science misuse and polarised political narratives in the COVID-19 response.
    Lancet. 2020 Oct 19. pii: S0140-6736(20)32168.
    PubMed        

  40. USUELLI M
    The Lombardy region of Italy launches the first investigative COVID-19 commission.
    Lancet. 2020 Oct 15. pii: S0140-6736(20)32154.
    PubMed        

  41. POLAND GA, Ovsyannikova IG, Kennedy RB
    SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates.
    Lancet. 2020 Oct 13. pii: S0140-6736(20)32137.
    PubMed         Abstract available

  42. PEIRIS M, Leung GM
    What can we expect from first-generation COVID-19 vaccines?
    Lancet. 2020 Sep 21. pii: S0140-6736(20)31976.
    PubMed        

  43. MENNI C, Sudre CH, Steves CJ, Ourselin S, et al
    Widespread smell testing for COVID-19 has limited application - Authors' reply.
    Lancet. 2020 Nov 3. pii: S0140-6736(20)32316.
    PubMed        

  44. HOPKINS C, Smith B
    Widespread smell testing for COVID-19 has limited application.
    Lancet. 2020 Nov 3. pii: S0140-6736(20)32317.
    PubMed        

  45. THE LANCET
    COVID-19 in Latin America: a humanitarian crisis.
    Lancet. 2020;396:1463.
    PubMed        

  46. DZAU VJ, Balatbat C
    Strategy, coordinated implementation, and sustainable financing needed for COVID-19 innovations.
    Lancet. 2020;396:1469-1471.
    PubMed        

  47. WILDER-SMITH A, Cook AR, Dickens BL
    Institutional versus home isolation to curb the COVID-19 outbreak - Authors' reply.
    Lancet. 2020 Nov 6. pii: S0140-6736(20)32171.
    PubMed        

  48. BHADORIA AS, Gawande K, Sharma R, Mohapatra A, et al
    Institutional versus home isolation to curb the COVID-19 outbreak.
    Lancet. 2020 Nov 6. pii: S0140-6736(20)32161.
    PubMed        

  49. HILLS T, Kearns N, Kearns C, Beasley R, et al
    Influenza control during the COVID-19 pandemic.
    Lancet. 2020;396:1633-1634.
    PubMed        


    Lancet Oncol

  50. SHARMA DC
    India-China border standoff raises concerns on drug supplies.
    Lancet Oncol. 2020;21:1408-1409.
    PubMed        

  51. BURKI TK
    Burnout among cancer professionals during COVID-19.
    Lancet Oncol. 2020 Sep 24. pii: S1470-2045(20)30584.
    PubMed        

  52. THE LANCET ONCOLOGY
    UK cancer care threatened by government incompetence.
    Lancet Oncol. 2020;21:1387.
    PubMed        


    N Engl J Med

  53. DOLIN R, Hirsch MS
    Remdesivir - An Important First Step.
    N Engl J Med. 2020;383:1886-1887.
    PubMed        

  54. GOODING R, Myers B, Salta S
    Lupus Anticoagulant in Patients with Covid-19.
    N Engl J Med. 2020;383.
    PubMed        

  55. PLATTON S, Bowles L, Pasi KJ
    Lupus Anticoagulant in Patients with Covid-19. Reply.
    N Engl J Med. 2020;383.
    PubMed        

  56. RASMUSSEN AL, Escandon K, Popescu SV
    Facial Masking for Covid-19.
    N Engl J Med. 2020;383.
    PubMed        

  57. BROSSEAU LM, Roy CJ, Osterholm MT
    Facial Masking for Covid-19.
    N Engl J Med. 2020;383.
    PubMed        

  58. GANDHI M, Rutherford GW
    Facial Masking for Covid-19. Reply.
    N Engl J Med. 2020;383.
    PubMed        

  59. RUBIN EJ, Baden LR, Woodcock J, Morrissey S, et al
    Audio Interview: An Update from Operation Warp Speed.
    N Engl J Med. 2020;383:e127.
    PubMed        


    PLoS One

  60. GARCIA DEL CASTILLO-RODRIGUEZ , Ramos-Soler I, Lopez-Sanchez C, Quiles-Soler C, et al
    Information and communication technologies and quality of life in home confinement: Development and validation of the TICO scale.
    PLoS One. 2020;15:e0241948.
    PubMed         Abstract available

  61. ZDRAVKOVIC M, Berger-Estilita J, Zdravkovic B, Berger D, et al
    Scientific quality of COVID-19 and SARS CoV-2 publications in the highest impact medical journals during the early phase of the pandemic: A case control study.
    PLoS One. 2020;15:e0241826.
    PubMed         Abstract available

  62. WAKASHIMA K, Asai K, Kobayashi D, Koiwa K, et al
    The Japanese version of the Fear of COVID-19 scale: Reliability, validity, and relation to coping behavior.
    PLoS One. 2020;15:e0241958.
    PubMed         Abstract available

  63. SONG H, Cao X, Ye H, He L, et al
    Pattern of COVID-19 in Sichuan province, China: A descriptive epidemiological analysis.
    PLoS One. 2020;15:e0241470.
    PubMed         Abstract available

  64. ROMANO S, Fierro A, Liccardo A
    Beyond the peak: A deterministic compartment model for exploring the Covid-19 evolution in Italy.
    PLoS One. 2020;15:e0241951.
    PubMed         Abstract available

  65. LIMBU DK, Piryani RM, Sunny AK
    Healthcare workers' knowledge, attitude and practices during the COVID-19 pandemic response in a tertiary care hospital of Nepal.
    PLoS One. 2020;15:e0242126.
    PubMed         Abstract available

  66. BRANT-ZAWADZKI M, Fridman D, Robinson PA, Zahn M, et al
    SARS-CoV-2 antibody prevalence in health care workers: Preliminary report of a single center study.
    PLoS One. 2020;15:e0240006.
    PubMed         Abstract available

  67. LU P, Li X, Lu L, Zhang Y, et al
    The psychological states of people after Wuhan eased the lockdown.
    PLoS One. 2020;15:e0241173.
    PubMed         Abstract available

  68. AMMAR A, Mueller P, Trabelsi K, Chtourou H, et al
    Psychological consequences of COVID-19 home confinement: The ECLB-COVID19 multicenter study.
    PLoS One. 2020;15:e0240204.
    PubMed         Abstract available

  69. TRIAS-LLIMOS S, Riffe T, Bilal U
    Monitoring life expectancy levels during the COVID-19 pandemic: Example of the unequal impact of the first wave on Spanish regions.
    PLoS One. 2020;15:e0241952.
    PubMed         Abstract available

  70. ARNOLD MT, Temte JL, Barlow SK, Bell CJ, et al
    Comparison of participant-collected nasal and staff-collected oropharyngeal specimens for human ribonuclease P detection with RT-PCR during a community-based study.
    PLoS One. 2020;15:e0239000.
    PubMed         Abstract available

  71. KESKINOCAK P, Oruc BE, Baxter A, Asplund J, et al
    The impact of social distancing on COVID19 spread: State of Georgia case study.
    PLoS One. 2020;15:e0239798.
    PubMed         Abstract available

  72. DI CARLO P, Chiacchiaretta P, Sinjari B, Aruffo E, et al
    Air and surface measurements of SARS-CoV-2 inside a bus during normal operation.
    PLoS One. 2020;15:e0235943.
    PubMed         Abstract available

  73. SAMI R, Soltaninejad F, Amra B, Naderi Z, et al
    A one-year hospital-based prospective COVID-19 open-cohort in the Eastern Mediterranean region: The Khorshid COVID Cohort (KCC) study.
    PLoS One. 2020;15:e0241537.
    PubMed         Abstract available

  74. HUSSAIN I, Majeed A, Saeed H, Hashmi FK, et al
    A national study to assess pharmacists' preparedness against COVID-19 during its rapid rise period in Pakistan.
    PLoS One. 2020;15:e0241467.
    PubMed         Abstract available

  75. AGGARWAL K, Agarwal A, Jaiswal N, Dahiya N, et al
    Ocular surface manifestations of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis.
    PLoS One. 2020;15:e0241661.
    PubMed         Abstract available

  76. GAO C, Zhao Z, Li F, Liu JL, et al
    The impact of individual lifestyle and status on the acquisition of COVID-19: A case-Control study.
    PLoS One. 2020;15:e0241540.
    PubMed         Abstract available

  77. HO FK, Petermann-Rocha F, Gray SR, Jani BD, et al
    Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants.
    PLoS One. 2020;15:e0241824.
    PubMed         Abstract available

  78. FERRARI D, Milic J, Tonelli R, Ghinelli F, et al
    Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia-Challenges, strengths, and opportunities in a global health emergency.
    PLoS One. 2020;15:e0239172.
    PubMed         Abstract available

  79. MOHAPATRA S, Nath P, Chatterjee M, Das N, et al
    Repurposing therapeutics for COVID-19: Rapid prediction of commercially available drugs through machine learning and docking.
    PLoS One. 2020;15:e0241543.
    PubMed         Abstract available

  80. PLUMMER AR, du Bois JL, Flynn JM, Roesner J, et al
    A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model.
    PLoS One. 2020;15:e0242123.
    PubMed         Abstract available

  81. YANG Q, Yang X
    Incidence and risk factors of kidney impairment on patients with COVID-19: A meta-analysis of 10180 patients.
    PLoS One. 2020;15:e0241953.
    PubMed         Abstract available

  82. NG WCK, Mbadjeu Hondjeu AR, Syrett A, Caragata R, et al
    Subject validation of reusable N95 stop-gap filtering facepiece respirators in COVID-19 pandemic.
    PLoS One. 2020;15:e0242304.
    PubMed         Abstract available

  83. GORI A, Topino E, Di Fabio A
    The protective role of life satisfaction, coping strategies and defense mechanisms on perceived stress due to COVID-19 emergency: A chained mediation model.
    PLoS One. 2020;15:e0242402.
    PubMed         Abstract available

  84. REGINA J, Papadimitriou-Olivgeris M, Burger R, Le Pogam MA, et al
    Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: An observational retrospective study.
    PLoS One. 2020;15:e0240781.
    PubMed         Abstract available

  85. LILLERI D, Zavaglio F, Gabanti E, Gerna G, et al
    Analysis of the SARS-CoV-2 epidemic in Italy: The role of local and interventional factors in the control of the epidemic.
    PLoS One. 2020;15:e0242305.
    PubMed         Abstract available

  86. RAJARAMAN S, Sornapudi S, Alderson PO, Folio LR, et al
    Analyzing inter-reader variability affecting deep ensemble learning for COVID-19 detection in chest radiographs.
    PLoS One. 2020;15:e0242301.
    PubMed         Abstract available

  87. OETJENS MT, Luo JZ, Chang A, Leader JB, et al
    Electronic health record analysis identifies kidney disease as the leading risk factor for hospitalization in confirmed COVID-19 patients.
    PLoS One. 2020;15:e0242182.
    PubMed         Abstract available

  88. GRAZIADIO S, Urwin SG, Cocco P, Micocci M, et al
    Unmet clinical needs for COVID-19 tests in UK health and social care settings.
    PLoS One. 2020;15:e0242125.
    PubMed         Abstract available

  89. RIEG S, von Cube M, Kalbhenn J, Utzolino S, et al
    COVID-19 in-hospital mortality and mode of death in a dynamic and non-restricted tertiary care model in Germany.
    PLoS One. 2020;15:e0242127.
    PubMed         Abstract available

  90. BOURDILLON N, Yazdani S, Schmitt L, Millet GP, et al
    Effects of COVID-19 lockdown on heart rate variability.
    PLoS One. 2020;15:e0242303.
    PubMed         Abstract available

  91. KENMOE S, Kengne-Nde C, Ebogo-Belobo JT, Mbaga DS, et al
    Systematic review and meta-analysis of the prevalence of common respiratory viruses in children < 2 years with bronchiolitis in the pre-COVID-19 pandemic era.
    PLoS One. 2020;15:e0242302.
    PubMed         Abstract available

  92. WANG S, Chen Z, Lin Y, Lin L, et al
    Clinical characteristics of 199 discharged patients with COVID-19 in Fujian Province: A multicenter retrospective study between January 22nd and February 27th, 2020.
    PLoS One. 2020;15:e0242307.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  93. SENDER V, Hentrich K, Pathak A, Tan Qian Ler A, et al
    Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2012265117.
    PubMed         Abstract available


    Vaccine

  94. GANGULY M, Yeolekar L, Tyagi P, Sagar U, et al
    Evaluation of manufacturing feasibility and safety of an MDCK cell-based live attenuated influenza vaccine (LAIV) platform.
    Vaccine. 2020 Nov 20. pii: S0264-410X(20)31424.
    PubMed         Abstract available

  95. DRORI Y, Pando R, Sefty H, Rosenberg A, et al
    Influenza vaccine effectiveness against laboratory-confirmed influenza in a vaccine-mismatched influenza B-dominant season.
    Vaccine. 2020 Nov 23. pii: S0264-410X(20)31394.
    PubMed         Abstract available

  96. KITTIKRAISAK W, Phadungkiatwatana P, Ditsungnoen D, Kaoiean S, et al
    Comparison of influenza antibody titers among women who were vaccinated in the 2(nd) and the 3(rd) trimesters of pregnancy.
    Vaccine. 2020 Nov 23. pii: S0264-410X(20)31472.
    PubMed         Abstract available

  97. HAVERI A, Ikonen N, Savolainen-Kopra C, Julkunen I, et al
    Long-lasting heterologous antibody responses after sequential vaccination with A/Indonesia/5/2005 and A/Vietnam/1203/2004 pre-pandemic influenza A(H5N1) virus vaccines.
    Vaccine. 2020 Nov 24. pii: S0264-410X(20)31494.
    PubMed         Abstract available


Thank you for your interest in scientific medicine.


AMEDEO Influenza is free of charge.
This policy is made possible thanks to a media sponsorship by Boehringer Ingelheim.

Design: