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Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Gastric Cancer

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Articles published in Cancer Lett

Retrieve available abstracts of 41 articles:
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Single Articles


    June 2025
  1. GERAKOPOULOS V, Ramos C, Muller C, Walterskirchen N, et al
    Single-cell transcriptomic analysis identifies tissue-specific fibroblasts as the main modulators of myeloid cells in peritoneal metastasis of different origin.
    Cancer Lett. 2025;620:217678.
    PubMed     Abstract available


    April 2025
  2. LIU Q, Yu M, Lin Z, Wu L, et al
    COL1A1-positive endothelial cells promote gastric cancer progression via the ANGPTL4-SDC4 axis driven by endothelial-to-mesenchymal transition.
    Cancer Lett. 2025;623:217731.
    PubMed     Abstract available


    March 2025
  3. LUO D, Wang H, Liu J, Chen X, et al
    Combined MDM2 and G2/M checkpoint inhibition induces synergistic antitumor response in gastric signet-ring cell carcinoma.
    Cancer Lett. 2025;613:217500.
    PubMed     Abstract available


  4. YANG D, Zhang X, Hu Z, Sun Q, et al
    Organoid-based single cell sequencing revealed the lineage evolution during docetaxel treatment in gastric cancer.
    Cancer Lett. 2025 Mar 19:217617. doi: 10.1016/j.canlet.2025.217617.
    PubMed     Abstract available


  5. WEI R, Song J, Liu C, Zhao Z, et al
    FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity.
    Cancer Lett. 2025;612:217475.
    PubMed     Abstract available


    February 2025
  6. LI N, Tong H, Hou W, Liu Q, et al
    Neural-cancer Crosstalk: Reciprocal Molecular Circuits Driving Gastric Tumorigenesis and Emerging Therapeutic Opportunities.
    Cancer Lett. 2025 Feb 25:217589. doi: 10.1016/j.canlet.2025.217589.
    PubMed     Abstract available


  7. XU X, Huang Z, Han H, Yu Z, et al
    N(7)-methylguanosine tRNA modification promotes gastric cancer progression by activating SDHAF4-dependent mitochondrial oxidative phosphorylation.
    Cancer Lett. 2025;615:217566.
    PubMed     Abstract available


  8. LI X, Lu J, Chen F, Yuan J, et al
    Comprehensive proteomic analysis and multidimensional model construction of peritoneal metastasis in gastric cancer.
    Cancer Lett. 2025 Feb 4:217509. doi: 10.1016/j.canlet.2025.217509.
    PubMed     Abstract available


    December 2024
  9. MAK TK, Li K, Zhao Z, Wang K, et al
    m6A demethylation of NNMT in CAFs promotes gastric cancer progression by enhancing macrophage M2 polarization.
    Cancer Lett. 2024 Dec 24:217422. doi: 10.1016/j.canlet.2024.217422.
    PubMed     Abstract available


  10. TSUTSUMI C, Ohuchida K, Tsutsumi H, Shimada Y, et al
    TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer.
    Cancer Lett. 2024 Dec 23:217412. doi: 10.1016/j.canlet.2024.217412.
    PubMed     Abstract available


  11. YUAN J, Lu J, Zhu J, Chen F, et al
    LncRNA FIRRE drives gastric cancer progression via ZFP64-mediated TUBB3 promoter activation.
    Cancer Lett. 2024 Dec 18:217398. doi: 10.1016/j.canlet.2024.217398.
    PubMed     Abstract available


    November 2024
  12. YOSHIMURA K, Zou G, Fan Y, Yamashita K, et al
    HSP90 Inhibitor AUY922 Suppresses Tumor Growth and Modulates Immune Response through YAP-TEAD Pathway Inhibition in Gastric Cancer.
    Cancer Lett. 2024 Nov 25:217354. doi: 10.1016/j.canlet.2024.217354.
    PubMed     Abstract available


    July 2024
  13. YANG R, Kwan W, Du Y, Yan R, et al
    Corrigendum to "Drug-induced senescence by aurora kinase inhibitors attenuates innate immune response of macrophages on gastric cancer organoids" [Cancer Lett. 598 (2024) 217106].
    Cancer Lett. 2024 Jul 30:217127. doi: 10.1016/j.canlet.2024.217127.
    PubMed    


  14. YANG R, Kwan W, Du Y, Yan R, et al
    Drug-induced senescence by aurora kinase inhibitors attenuates innate immune response of macrophages on gastric cancer organoids.
    Cancer Lett. 2024 Jul 9:217106. doi: 10.1016/j.canlet.2024.217106.
    PubMed     Abstract available


  15. GOMAA A, Maacha S, Peng D, Soutto M, et al
    SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation.
    Cancer Lett. 2024;593:216939.
    PubMed     Abstract available


    June 2024
  16. LIM SH, Saluja A, Vickers S, Hong JY, et al
    The safety and efficacy outcomes of Minnelide given alone or in combination with paclitaxel in advanced gastric cancer: a Phase I trial.
    Cancer Lett. 2024 Jun 10:217041. doi: 10.1016/j.canlet.2024.217041.
    PubMed     Abstract available


    May 2024
  17. LEI T, Lin Y, Lai X, Zhang Y, et al
    ITGB5 facilitates gastric cancer metastasis by promoting TGFBR2 endosomal recycling.
    Cancer Lett. 2024;592:216953.
    PubMed     Abstract available


  18. XIA Y, Jiang T, Li Y, Gu C, et al
    circVAPA-rich small extracellular vesicles derived from gastric cancer promote neural invasion by inhibiting SLIT2 expression in neuronal cells.
    Cancer Lett. 2024 May 5:216926. doi: 10.1016/j.canlet.2024.216926.
    PubMed     Abstract available


    April 2024
  19. ZHANG J, Fu L, Wang H, Yonemura A, et al
    RAC1-mediated Integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination.
    Cancer Lett. 2024 Apr 17:216901. doi: 10.1016/j.canlet.2024.216901.
    PubMed     Abstract available


  20. CHEN J, Ji Y, Liu Y, Cen Z, et al
    Exhaled volatolomics profiling facilitates personalized screening for gastric cancer.
    Cancer Lett. 2024;590:216881.
    PubMed     Abstract available


  21. WANG L, Mao X, Yu X, Su J, et al
    FPR3 reprograms glycolytic metabolism and stemness in gastric cancer via calcium-NFATc1 pathway.
    Cancer Lett. 2024 Apr 11:216841. doi: 10.1016/j.canlet.2024.216841.
    PubMed     Abstract available


  22. ZHANG Y, Lin W, Yang Y, Zhu S, et al
    MEF2D facilitates liver metastasis of gastric cancer cells through directly inducing H1X under IL-13 stimulation.
    Cancer Lett. 2024 Apr 10:216878. doi: 10.1016/j.canlet.2024.216878.
    PubMed     Abstract available


  23. WEN W, Ertas YN, Erdem A, Zhang Y, et al
    Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy.
    Cancer Lett. 2024 Apr 5:216857. doi: 10.1016/j.canlet.2024.216857.
    PubMed     Abstract available


    March 2024
  24. RIEGEL G, Orvain C, Recberlik S, Spaety ME, et al
    The unfolded protein response-glutathione metabolism axis: A novel target of a cycloruthenated complexes bypassing tumor resistance mechanisms.
    Cancer Lett. 2024;585:216671.
    PubMed     Abstract available


  25. ZHAO Z, Cai Z, Zhang S, Yin X, et al
    Activation of the FOXM1/ASF1B/PRDX3 axis confers hyperproliferative and antioxidative stress reactivity to gastric cancer.
    Cancer Lett. 2024 Mar 25:216796. doi: 10.1016/j.canlet.2024.216796.
    PubMed     Abstract available


    February 2024
  26. CHANG M, Sun Q, Cui X, Wang Y, et al
    Lnc-PLCB1 is stabilized by METTL14 induced m6A modification and inhibits Helicobacter pylori mediated gastric cancer by destabilizing DDX21.
    Cancer Lett. 2024 Feb 20:216746. doi: 10.1016/j.canlet.2024.216746.
    PubMed     Abstract available


  27. LIN C, Lin P, Yao H, Liu S, et al
    Modulation of YBX1-mediated PANoptosis inhibition by PPM1B and USP10 confers chemoresistance to oxaliplatin in gastric cancer.
    Cancer Lett. 2024 Feb 14:216712. doi: 10.1016/j.canlet.2024.216712.
    PubMed     Abstract available


  28. LIANG B, Wu Q, Wang Y, Shi Y, et al
    Cdc42-driven endosomal cholesterol transport promotes collateral resistance in HER2-positive gastric cancer.
    Cancer Lett. 2024 Feb 7:216702. doi: 10.1016/j.canlet.2024.216702.
    PubMed     Abstract available


    January 2024
  29. CHEN P, Zhong X, Song Y, Zhong W, et al
    Triptolide induces apoptosis and cytoprotective autophagy by ROS accumulation via directly targeting peroxiredoxin 2 in gastric cancer cells.
    Cancer Lett. 2024 Jan 19:216622. doi: 10.1016/j.canlet.2024.216622.
    PubMed     Abstract available


  30. WU QN, Qi J, Liu ZK, Luo XJ, et al
    HIPK3 maintains sensitivity to platinum drugs and prevents disease progression in gastric cancer.
    Cancer Lett. 2024 Jan 19:216643. doi: 10.1016/j.canlet.2024.216643.
    PubMed     Abstract available


  31. WENG N, Zhou C, Zhou Y, Zhong Y, et al
    IKZF4/NONO-RAB11FIP3 axis promotes immune evasion in gastric cancer via facilitating PD-L1 endosome recycling.
    Cancer Lett. 2024 Jan 9:216618. doi: 10.1016/j.canlet.2024.216618.
    PubMed     Abstract available


    November 2023
  32. WANG H, Zhou Z, Zhang J, Hao T, et al
    Pumilio1 regulates NPM3/NPM1 axis to promote PD-L1-mediated immune escape in gastric cancer.
    Cancer Lett. 2023;581:216498.
    PubMed     Abstract available


  33. JIANG T, Xia Y, Li Y, Lu C, et al
    TRIM29 promotes antitumor immunity through enhancing IGF2BP1 ubiquitination and subsequent PD-L1 downregulation in gastric cancer.
    Cancer Lett. 2023;581:216510.
    PubMed     Abstract available


    October 2023
  34. FENG W, Ma C, Rao H, Zhang W, et al
    Setd2 deficiency promotes gastric tumorigenesis through inhibiting the SIRT1/FOXO pathway.
    Cancer Lett. 2023 Oct 30:216470. doi: 10.1016/j.canlet.2023.216470.
    PubMed     Abstract available


  35. HUA H, Su T, Han L, Zhang L, et al
    LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing beta-catenin protein.
    Cancer Lett. 2023 Oct 6:216436. doi: 10.1016/j.canlet.2023.216436.
    PubMed     Abstract available


    September 2023
  36. LI J, Feng H, Zhu J, Yang K, et al
    Gastric cancer derived exosomal THBS1 enhanced Vgamma9Vdelta2 T-cell function through activating RIG-I-like receptor signaling pathway in a N6-methyladenosine methylation dependent manner.
    Cancer Lett. 2023 Sep 30:216410. doi: 10.1016/j.canlet.2023.216410.
    PubMed     Abstract available


    August 2023
  37. MAO D, Zhou Z, Chen H, Liu X, et al
    Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer.
    Cancer Lett. 2023 Aug 15:216351. doi: 10.1016/j.canlet.2023.216351.
    PubMed     Abstract available


  38. ANDREUCCI E, Biagioni A, Peri S, Versienti G, et al
    The CAIX inhibitor SLC-0111 exerts anti-cancer activity on gastric cancer cell lines and resensitizes resistant cells to 5-Fluorouracil, taxane-derived, and platinum-based drugs.
    Cancer Lett. 2023 Aug 5:216338. doi: 10.1016/j.canlet.2023.216338.
    PubMed     Abstract available


    July 2023
  39. ZHAO P, Yuan F, Xu L, Jin Z, et al
    HKDC1 reprograms lipid metabolism to enhance gastric cancer metastasis and cisplatin resistance via forming a ribonucleoprotein complex.
    Cancer Lett. 2023 Jul 7:216305. doi: 10.1016/j.canlet.2023.216305.
    PubMed     Abstract available


    May 2023
  40. CHEN Z, Xu P, Wang X, Li Y, et al
    MSC-NPRA loop drives fatty acid oxidation to promote stemness and chemoresistance of gastric cancer.
    Cancer Lett. 2023;565:216235.
    PubMed     Abstract available


    April 2023
  41. LI M, Mei YX, Wen JH, Jiao YR, et al
    Hepatoid adenocarcinoma-Clinicopathological features and molecular characteristics.
    Cancer Lett. 2023;559:216104.
    PubMed     Abstract available


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