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Articles published in PLoS Genet

Retrieve available abstracts of 95 articles:
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Single Articles


    October 2026
  1. ANAND P, Liu A, Dang M, Fu B, et al
    GPC: An expressive and tractable deep generative model for genetic variation data.
    PLoS Genet. 2026;22:e1012321.
    PubMed     Abstract available


    September 2026
  2. KURTYAN E, Stein AJ, Abdalla KJ, Yuan Z, et al
    Characterization of METTL3/14-mediated m6A modification in human transcriptome using Nanopore direct RNA sequencing.
    PLoS Genet. 2026;22:e1012278.
    PubMed     Abstract available


  3. CANIDA T, Ye Z, Wang SH, Huang HH, et al
    FM-GPT: Bayesian fine mapping for phenome-wide transcriptome-wide association studies.
    PLoS Genet. 2026;22:e1012126.
    PubMed     Abstract available


  4. BRASO-VIVES M, Hartasanchez DA, Pulido A, Bertrand S, et al
    The highly heterozygous European amphioxus (Branchiostoma lanceolatum) at the edge of panmixia.
    PLoS Genet. 2026;22:e1012293.
    PubMed     Abstract available


  5. GARG E, Romain J, Sun L, Paterson AD, et al
    Assessing Hardy-Weinberg equilibrium in T2T-aligned 1000 genomes project.
    PLoS Genet. 2026;22:e1012280.
    PubMed     Abstract available


  6. RICHLAND J, Kiiskinen T, Wang W, Lu WS, et al
    Univariate-guided sparse regression for Biobank-scale high-dimensional omics data.
    PLoS Genet. 2026;22:e1012314.
    PubMed     Abstract available


    August 2026
  7. JOHRI P, Pouyet F, Charlesworth B
    The rights and wrongs of rescaling in population genetics simulations.
    PLoS Genet. 2026;22:e1012261.
    PubMed     Abstract available


  8. ABDELGHANY S, Helmkampf M, Schechter MS, Veseli IA, et al
    Proteobacteria with chemosynthetic potential are highly prevalent in the gills of Hypoplectrus reef fishes.
    PLoS Genet. 2026;22:e1012266.
    PubMed     Abstract available


    July 2026
  9. FEROLITO BR, Horimoto ARVR, Gravel-Pucillo K, Golden DJ, et al
    A genomic-led strategy to anticipate drug safety effects.
    PLoS Genet. 2026;22:e1012211.
    PubMed     Abstract available


  10. DE VIENNE D, de Vienne DM
    Age-based risk estimates for C9orf72RE-related diseases: Theoretical developments and added value for genetic counseling.
    PLoS Genet. 2026;22:e1012230.
    PubMed     Abstract available


  11. BROWNING SR, Temple SD, Browning BL
    Local ancestry inference with poorly-matched reference panels.
    PLoS Genet. 2026;22:e1011919.
    PubMed     Abstract available


    March 2026
  12. WEINREICH DM, Sgouros T, Raynes Y, Burtsev H, et al
    Wanted: A population genetic theory of biological noise regulation.
    PLoS Genet. 2026;22:e1012066.
    PubMed     Abstract available


  13. DIAZ-PAPKOVICH A, Zabad S, Snell H, Ben-Eghan C, et al
    Topological stratification of continuous genetic variation in large biobanks.
    PLoS Genet. 2026;22:e1012068.
    PubMed     Abstract available


    January 2026
  14. WITONSKY D, Laxman B, Usman H, Bielski MC, et al
    Genomic profiling of active vitamin D colonic responses in African- and European-Americans identifies an ancestry-related regulatory variant of POLB.
    PLoS Genet. 2026;22:e1011983.
    PubMed     Abstract available


  15. MEZZELL AT, Zhang Y, Perez AM, Vest KE, et al
    Oculopharyngeal muscular dystrophy (OPMD) associated alanine expansion impairs the function of the nuclear polyadenosine RNA binding protein PABPN1 as revealed by proximity labeling and comparative proteomics.
    PLoS Genet. 2026;22:e1011743.
    PubMed     Abstract available


  16. LIN L, Li Y, Ji F, Lin J, et al
    Shared latent genetic liability across fibromyalgia and psychiatric traits: Novel insights from genomic structural equation modeling.
    PLoS Genet. 2026;22:e1012034.
    PubMed     Abstract available


    December 2025
  17. HUANG B, Durvasula A, Mousavi N, Ziaei-Jam H, et al
    Genome-wide selection inference at short tandem repeats.
    PLoS Genet. 2025;21:e1011959.
    PubMed     Abstract available


    November 2025
  18. COELHO MA, David-Palma M, Kachalkin AV, Kolarik M, et al
    Genomic and phenotypic insights into the expanding phylogenetic landscape of the Cryptococcus genus.
    PLoS Genet. 2025;21:e1011945.
    PubMed     Abstract available


    October 2025
  19. MICHEL E, Moreau C, Gagnon L, Gagnon M, et al
    Rare diseases load through the study of a regional population.
    PLoS Genet. 2025;21:e1011876.
    PubMed     Abstract available


  20. SMITH CL, Stark BC, Kobalter M, Barks MC, et al
    Factors influencing trustworthiness and perceived biases of medical information and genetic testing for Black and White Americans.
    PLoS Genet. 2025;21:e1011800.
    PubMed     Abstract available


    September 2025
  21. SHASTRY V, Musiani M, Novembre J
    Jointly representing long-range genetic similarity and spatially heterogeneous isolation-by-distance.
    PLoS Genet. 2025;21:e1011612.
    PubMed     Abstract available


  22. DO O I, Gaggiotti OE, de Villemereuil P, Goudet J, et al
    A method for identifying local adaptation in structured populations.
    PLoS Genet. 2025;21:e1011871.
    PubMed     Abstract available


  23. ZHU N, Zhao Y, Yi W, Jiang L, et al
    Genomic profiling and experimental validation of type VI secretion system-associated proteins in Klebsiella.
    PLoS Genet. 2025;21:e1011878.
    PubMed     Abstract available


  24. YANG Y, Lawson DJ
    From individuals to ancestries: Towards attributing trait variation to haplotypes.
    PLoS Genet. 2025;21:e1011883.
    PubMed     Abstract available


    August 2025
  25. LYU Z, Si G, Xing M, Li W, et al
    Circulating proteins associated with histological subtypes of lung cancer from genetic and population-based perspectives.
    PLoS Genet. 2025;21:e1011821.
    PubMed     Abstract available


  26. OLLIVIER L, Charlesworth B, Pouyet F
    Beyond recombination: Exploring the impact of meiotic frequency on genome-wide genetic diversity.
    PLoS Genet. 2025;21:e1011798.
    PubMed     Abstract available


    July 2025
  27. FINE AG, Steinrucken M
    A novel expectation-maximization approach to infer general diploid selection from time-series genetic data.
    PLoS Genet. 2025;21:e1011769.
    PubMed     Abstract available


    June 2025
  28. ISSHIKI M, Griffen AJ, Meissner P, Spencer P, et al
    Genetic disease risks of under-represented founder populations in New York City.
    PLoS Genet. 2025;21:e1011755.
    PubMed     Abstract available


    April 2025
  29. EBDON S, Laetsch DR, Vila R, Baird SJE, et al
    Genomic regions of current low hybridisation mark long-term barriers to gene flow in scarce swallowtail butterflies.
    PLoS Genet. 2025;21:e1011655.
    PubMed     Abstract available


  30. CAI W, Cole JB, Goddard ME, Li J, et al
    Mammary gland multi-omics data reveals new genetic insights into milk production traits in dairy cattle.
    PLoS Genet. 2025;21:e1011675.
    PubMed     Abstract available


  31. HEY J, Pavinato VAC
    Isolating selective from non-selective forces using site frequency ratios.
    PLoS Genet. 2025;21:e1011427.
    PubMed     Abstract available


    March 2025
  32. GETZ LJ, Robinson OS, Thomas NA
    Functional genomics of chitin degradation by Vibrio parahaemolyticus reveals finely integrated metabolic contributions to support environmental fitness.
    PLoS Genet. 2025;21:e1011370.
    PubMed     Abstract available


  33. RAGSDALE AP
    Archaic introgression and the distribution of shared variation under stabilizing selection.
    PLoS Genet. 2025;21:e1011623.
    PubMed     Abstract available


  34. LECOQUIERRE F, Drouot N, Coutant S, Quenez O, et al
    Parental germline mosaicism in genome-wide phased de novo variants: Recurrence risk assessment and implications for precision genetic counselling.
    PLoS Genet. 2025;21:e1011651.
    PubMed     Abstract available


  35. FARNITANO MC, Karoly K, Sweigart AL
    Fluctuating reproductive isolation and stable ancestry structure in a fine-scaled mosaic of hybridizing Mimulus monkeyflowers.
    PLoS Genet. 2025;21:e1011624.
    PubMed     Abstract available


  36. TRAN JS, Ward RD, Iruegas-Lopez R, Ebersberger I, et al
    Chemical genomics informs antibiotic and essential gene function in Acinetobacter baumannii.
    PLoS Genet. 2025;21:e1011642.
    PubMed     Abstract available


    January 2025
  37. HUANG Z, Kelleher J, Chan YB, Balding D, et al
    Estimating evolutionary and demographic parameters via ARG-derived IBD.
    PLoS Genet. 2025;21:e1011537.
    PubMed     Abstract available


    December 2024
  38. AMEZQUITA J, Desbois M, Opperman KJ, Pak JS, et al
    Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development.
    PLoS Genet. 2024;20:e1011496.
    PubMed     Abstract available


  39. OMKAR S, Mitchem MM, Hoskins JR, Shrader C, et al
    Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.
    PLoS Genet. 2024;20:e1011338.
    PubMed     Abstract available


  40. HASAN A, Whitlock MC
    FST and genetic diversity in an island model with background selection.
    PLoS Genet. 2024;20:e1011225.
    PubMed     Abstract available


  41. HAASL RJ, Payseur BA
    Fitness landscapes of human microsatellites.
    PLoS Genet. 2024;20:e1011524.
    PubMed     Abstract available


    November 2024
  42. XU Z, Wei P
    A novel statistical framework for meta-analysis of total mediation effect with high-dimensional omics mediators in large-scale genomic consortia.
    PLoS Genet. 2024;20:e1011483.
    PubMed     Abstract available


    October 2024
  43. SKIADAS P, Riera Vidal S, Dommisse J, Mendel MN, et al
    Pangenome graph analysis reveals extensive effector copy-number variation in spinach downy mildew.
    PLoS Genet. 2024;20:e1011452.
    PubMed     Abstract available


  44. FU S, Wheeler W, Wang X, Hua X, et al
    A comprehensive framework for trans-ancestry pathway analysis using GWAS summary data from diverse populations.
    PLoS Genet. 2024;20:e1011322.
    PubMed     Abstract available


    September 2024
  45. KYRIAZIS CC, Lohmueller KE
    Constraining models of dominance for nonsynonymous mutations in the human genome.
    PLoS Genet. 2024;20:e1011198.
    PubMed     Abstract available


    August 2024
  46. SHOGREN EH, Sardell JM, Muirhead CA, Marti E, et al
    Recent secondary contact, genome-wide admixture, and asymmetric introgression of neo-sex chromosomes between two Pacific island bird species.
    PLoS Genet. 2024;20:e1011360.
    PubMed     Abstract available


  47. CRONE B, Boyle AP
    Enhancing portability of trans-ancestral polygenic risk scores through tissue-specific functional genomic data integration.
    PLoS Genet. 2024;20:e1011356.
    PubMed     Abstract available


    July 2024
  48. RUEDA-M N, Pardo-Diaz C, Montejo-Kovacevich G, McMillan WO, et al
    Genomic evidence reveals three W-autosome fusions in Heliconius butterflies.
    PLoS Genet. 2024;20:e1011318.
    PubMed     Abstract available


  49. GUTIERREZ-GUERRERO YT, Phifer-Rixey M, Nachman MW
    Across two continents: The genomic basis of environmental adaptation in house mice (Mus musculus domesticus) from the Americas.
    PLoS Genet. 2024;20:e1011036.
    PubMed     Abstract available


  50. WERTENBROEK R, Hofmeister RJ, Xenarios I, Thoma Y, et al
    Improving population scale statistical phasing with whole-genome sequencing data.
    PLoS Genet. 2024;20:e1011092.
    PubMed     Abstract available


    June 2024
  51. DAVISON C, Tallman S, de Ste-Croix M, Antonio M, et al
    Long-term evolution of Streptococcus mitis and Streptococcus pneumoniae leads to higher genetic diversity within rather than between human populations.
    PLoS Genet. 2024;20:e1011317.
    PubMed     Abstract available


    April 2024
  52. CHO A, Lax G, Livingston SJ, Masukagami Y, et al
    Genomic analyses of Symbiomonas scintillans show no evidence for endosymbiotic bacteria but does reveal the presence of giant viruses.
    PLoS Genet. 2024;20:e1011218.
    PubMed     Abstract available


  53. DUMONT BL, Gatti DM, Ballinger MA, Lin D, et al
    Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.
    PLoS Genet. 2024;20:e1011228.
    PubMed     Abstract available


  54. GUNN S, Lunetta KL
    Correlation-based tests for the formal comparison of polygenic scores in multiple populations.
    PLoS Genet. 2024;20:e1011249.
    PubMed     Abstract available


  55. MOORE MP, Laager M, Ribeca P, Didelot X, et al
    KmerAperture: Retaining k-mer synteny for alignment-free extraction of core and accessory differences between bacterial genomes.
    PLoS Genet. 2024;20:e1011184.
    PubMed     Abstract available


    March 2024
  56. WARD CM, Onetto CA, Van Den Heuvel S, Cuijvers KM, et al
    Recombination, admixture and genome instability shape the genomic landscape of Saccharomyces cerevisiae derived from spontaneous grape ferments.
    PLoS Genet. 2024;20:e1011223.
    PubMed     Abstract available


  57. LUO Z, McTaggart A, Schwessinger B
    Genome biology and evolution of mating-type loci in four cereal rust fungi.
    PLoS Genet. 2024;20:e1011207.
    PubMed     Abstract available


    February 2024
  58. RIVAS-GONZALEZ I, Schierup MH, Wakeley J, Hobolth A, et al
    TRAILS: Tree reconstruction of ancestry using incomplete lineage sorting.
    PLoS Genet. 2024;20:e1010836.
    PubMed     Abstract available


  59. RAY DD, Flagel L, Schrider DR
    IntroUNET: Identifying introgressed alleles via semantic segmentation.
    PLoS Genet. 2024;20:e1010657.
    PubMed     Abstract available


    January 2024
  60. ZHANG QX, Liu T, Guo X, Zhen J, et al
    Searching across-cohort relatives in 54,092 GWAS samples via encrypted genotype regression.
    PLoS Genet. 2024;20:e1011037.
    PubMed     Abstract available


  61. LEWANSKI AL, Grundler MC, Bradburd GS
    The era of the ARG: An introduction to ancestral recombination graphs and their significance in empirical evolutionary genomics.
    PLoS Genet. 2024;20:e1011110.
    PubMed     Abstract available


    December 2023
  62. NOVAK LVF, Treitli SC, Pyrih J, Halakuc P, et al
    Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria.
    PLoS Genet. 2023;19:e1011050.
    PubMed     Abstract available


  63. KAWAI Y, Watanabe Y, Omae Y, Miyahara R, et al
    Exploring the genetic diversity of the Japanese population: Insights from a large-scale whole genome sequencing analysis.
    PLoS Genet. 2023;19:e1010625.
    PubMed     Abstract available


  64. LEGRAND C, Andriantsoa R, Lichter P, Raddatz G, et al
    Time-resolved, integrated analysis of clonally evolving genomes.
    PLoS Genet. 2023;19:e1011085.
    PubMed     Abstract available


  65. WANG D, Perera D, He J, Cao C, et al
    cLD: Rare-variant linkage disequilibrium between genomic regions identifies novel genomic interactions.
    PLoS Genet. 2023;19:e1011074.
    PubMed     Abstract available


  66. MUNASINGHE M, Read A, Stitzer MC, Song B, et al
    Combined analysis of transposable elements and structural variation in maize genomes reveals genome contraction outpaces expansion.
    PLoS Genet. 2023;19:e1011086.
    PubMed     Abstract available


    November 2023
  67. MO Z, Siepel A
    Domain-adaptive neural networks improve supervised machine learning based on simulated population genetic data.
    PLoS Genet. 2023;19:e1011032.
    PubMed     Abstract available


  68. MAROM R, Zhang B, Washington ME, Song IW, et al
    Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling.
    PLoS Genet. 2023;19:e1011005.
    PubMed     Abstract available


  69. AYALA NM, Genetti M, Corbett-Detig R
    Inferring multi-locus selection in admixed populations.
    PLoS Genet. 2023;19:e1011062.
    PubMed     Abstract available


  70. GOUDET J, Weir BS
    An allele-sharing, moment-based estimator of global, population-specific and population-pair FST under a general model of population structure.
    PLoS Genet. 2023;19:e1010871.
    PubMed     Abstract available


  71. MICHEL JC, Grivette MMB, Harshfield AT, Huynh L, et al
    Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold.
    PLoS Genet. 2023;19:e1011045.
    PubMed     Abstract available


    October 2023
  72. MOCCI E, Ward K, Perry JA, Starkweather A, et al
    Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits.
    PLoS Genet. 2023;19:e1010977.
    PubMed     Abstract available


  73. RADULESCU E, Chen Q, Pergola G, Di Carlo P, et al
    Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia.
    PLoS Genet. 2023;19:e1010989.
    PubMed     Abstract available


  74. AUBIN E, Llauro C, Garrigue J, Mirouze M, et al
    Genome-wide analysis of horizontal transfer in non-model wild species from a natural ecosystem reveals new insights into genetic exchange in plants.
    PLoS Genet. 2023;19:e1010964.
    PubMed     Abstract available


  75. CAURET CMS, Jordan DC, Kukoly LM, Burton SR, et al
    Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis.
    PLoS Genet. 2023;19:e1010990.
    PubMed     Abstract available


  76. WULFRIDGE P, Davidovich A, Salvador AC, Manno GC, et al
    Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation.
    PLoS Genet. 2023;19:e1010997.
    PubMed     Abstract available


    September 2023
  77. WEN X, Feng K, Qin J, Wei P, et al
    A detoxification pathway initiated by a nuclear receptor TcHR96h in Tetranychus cinnabarinus (Boisduval).
    PLoS Genet. 2023;19:e1010911.
    PubMed     Abstract available


  78. ROCA-UMBERT A, Garcia-Calleja J, Vogel-Gonzalez M, Fierro-Villegas A, et al
    Human genetic adaptation related to cellular zinc homeostasis.
    PLoS Genet. 2023;19:e1010950.
    PubMed     Abstract available


    August 2023
  79. TETERINA AA, Willis JH, Lukac M, Jovelin R, et al
    Genomic diversity landscapes in outcrossing and selfing Caenorhabditis nematodes.
    PLoS Genet. 2023;19:e1010879.
    PubMed     Abstract available


    July 2023
  80. WAGNER ER, Nightingale NM, Jen A, Overmyer KA, et al
    PKA regulatory subunit Bcy1 couples growth, lipid metabolism, and fermentation during anaerobic xylose growth in Saccharomyces cerevisiae.
    PLoS Genet. 2023;19:e1010593.
    PubMed     Abstract available


    June 2023
  81. NAKANO S, Kashio S, Nishimura K, Takeishi A, et al
    Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies.
    PLoS Genet. 2023;19:e1010761.
    PubMed     Abstract available


  82. BRISEVAC D, Prakash C, Kaiser TS
    Genetic analysis of a phenotypic loss in the mechanosensory entrainment of a circalunar clock.
    PLoS Genet. 2023;19:e1010763.
    PubMed     Abstract available


  83. SUN B, Kim H, Mello CC, Priess JR, et al
    The CERV protein of Cer1, a C. elegans LTR retrotransposon, is required for nuclear export of viral genomic RNA and can form giant nuclear rods.
    PLoS Genet. 2023;19:e1010804.
    PubMed     Abstract available


  84. VEDANAYAGAM J, Lin CJ, Papareddy R, Nodine M, et al
    Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts.
    PLoS Genet. 2023;19:e1010787.
    PubMed     Abstract available


  85. MIAO Y, Zhao Y, Wan S, Mei Q, et al
    Integrated analysis of genome-wide association studies and 3D epigenomic characteristics reveal the BMP2 gene regulating loin muscle depth in Yorkshire pigs.
    PLoS Genet. 2023;19:e1010820.
    PubMed     Abstract available


  86. WANG N, Cao S, Liu Z, Xiao H, et al
    Genomic conservation of crop wild relatives: A case study of citrus.
    PLoS Genet. 2023;19:e1010811.
    PubMed     Abstract available


    May 2023
  87. PISUPATI R, Nizhynska V, Molla Morales A, Nordborg M, et al
    On the causes of gene-body methylation variation in Arabidopsis thaliana.
    PLoS Genet. 2023;19:e1010728.
    PubMed     Abstract available


  88. JIANG MZ, Aguet F, Ardlie K, Chen J, et al
    Canonical correlation analysis for multi-omics: Application to cross-cohort analysis.
    PLoS Genet. 2023;19:e1010517.
    PubMed     Abstract available


    April 2023
  89. KOPPES EA, Johnson MA, Moresco JJ, Luppi P, et al
    Insulin secretion deficits in a Prader-Willi syndrome beta-cell model are associated with a concerted downregulation of multiple endoplasmic reticulum chaperones.
    PLoS Genet. 2023;19:e1010710.
    PubMed     Abstract available


  90. BRUAL T, Effantin G, Baltenneck J, Attaiech L, et al
    A natural single nucleotide mutation in the small regulatory RNA ArcZ of Dickeya solani switches off the antimicrobial activities against yeast and bacteria.
    PLoS Genet. 2023;19:e1010725.
    PubMed     Abstract available


    March 2023
  91. SLABODNICK MM, Tintori SC, Prakash M, Zhang P, et al
    Zyxin contributes to coupling between cell junctions and contractile actomyosin networks during apical constriction.
    PLoS Genet. 2023;19:e1010319.
    PubMed     Abstract available


  92. ONETTO CA, Kutyna DR, Kolouchova R, McCarthy J, et al
    SO2 and copper tolerance exhibit an evolutionary trade-off in Saccharomyces cerevisiae.
    PLoS Genet. 2023;19:e1010692.
    PubMed     Abstract available


  93. KRISHNAN S, DeMaere MZ, Beck D, Ostrowski M, et al
    Rhometa: Population recombination rate estimation from metagenomic read datasets.
    PLoS Genet. 2023;19:e1010683.
    PubMed     Abstract available


    February 2023
  94. XU L, Wang X, Lu X, Liang F, et al
    Long-read sequencing identifies novel structural variations in colorectal cancer.
    PLoS Genet. 2023;19:e1010514.
    PubMed     Abstract available


  95. NIELSEN SV, Vaughn AH, Leppala K, Landis MJ, et al
    Bayesian inference of admixture graphs on Native American and Arctic populations.
    PLoS Genet. 2023;19:e1010410.
    PubMed     Abstract available


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