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Articles published in Clin Cancer Res

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    May 2020
  1. SENGAL AT, Patch AM, Snell CE, Smith DS, et al
    FGFR2c mesenchymal isoform expression is associated with poor prognosis and further refines risk stratification within endometrial cancer molecular subtypes.
    Clin Cancer Res. 2020 May 15. pii: 1078-0432.CCR-19-4088.
    PubMed     Abstract available

  2. JI JX, Cochrane DR, Tessier-Cloutier B, Chen SY, et al
    Arginine depletion therapy with ADI-PEG20 limits tumor growth in argininosuccinate synthase deficient ovarian cancer, including small cell carcinoma of the ovary, hypercalcemic type.
    Clin Cancer Res. 2020 May 14. pii: 1078-0432.CCR-19-1905.
    PubMed     Abstract available

  3. LAMPERT EJ, Zimmer AS, Padget MR, Cimino-Mathews A, et al
    Combination of PARP inhibitor olaparib, and PD-L1 inhibitor durvalumab, in recurrent ovarian cancer: a proof-of-concept phase 2 study.
    Clin Cancer Res. 2020 May 12. pii: 1078-0432.CCR-20-0056.
    PubMed     Abstract available

    April 2020
  4. LI J, Pan C, Boese AC, Kang J, et al
    DGKA provides platinum resistance in ovarian cancer through activation of cJUN-WEE1 signaling.
    Clin Cancer Res. 2020 Apr 27. pii: 1078-0432.CCR-19-3790.
    PubMed     Abstract available

  5. HENSLEY ML, Chavan SS, Solit DB, Murali R, et al
    Genomic Landscape of Uterine Sarcomas Defined through Prospective Clinical Sequencing.
    Clin Cancer Res. 2020 Apr 16. pii: 1078-0432.CCR-19-3959.
    PubMed     Abstract available

  6. ARORA S, Balasubramaniam S, Zhang W, Zhang L, et al
    FDA Approval Summary: Pembrolizumab plus Lenvatinib for Endometrial Carcinoma, a Collaborative International Review under Project Orbis.
    Clin Cancer Res. 2020 Apr 15. pii: 1078-0432.CCR-19-3979.
    PubMed     Abstract available

    March 2020
  7. ROTMAN J, Heeren AM, Gassama AA, Lougheed SM, et al
    Adenocarcinoma of the uterine cervix shows impaired recruitment of cDC1 and CD8+ T cells and elevated beta-Catenin activation compared to squamous cell carcinoma.
    Clin Cancer Res. 2020 Mar 27. pii: 1078-0432.CCR-19-3826.
    PubMed     Abstract available

  8. YOU B, Robelin P, Tod M, Louvet C, et al
    CA-125 ELIMination rate constant K (KELIM) Is A Marker Of Chemosensitivity In Patients With Ovarian Cancer: Results from the Phase II CHIVA trial.
    Clin Cancer Res. 2020 Mar 24. pii: 1078-0432.CCR-20-0054.
    PubMed     Abstract available

  9. TISCHKOWITZ M, Huang S, Banerjee S, Hague J, et al
    Small Cell Carcinoma of the Ovary, Hypercalcaemic Type - genetics, new treatment targets and current management guidelines.
    Clin Cancer Res. 2020 Mar 10. pii: 1078-0432.CCR-19-3797.
    PubMed     Abstract available

    February 2020
  10. HARRIS RS, Serebrenik AA, Argyris P, Jarvis MC, et al
    The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer.
    Clin Cancer Res. 2020 Feb 14. pii: 1078-0432.CCR-19-2786.
    PubMed     Abstract available

    January 2020
  11. DHANI NC, Hirte HW, Wang L, Burnier JV, et al
    Phase II Trial of Cabozantinib in Recurrent/Metastatic Endometrial Cancer: A Study of the Princess Margaret, Chicago and California Consortia (NCI9322/PHL86).
    Clin Cancer Res. 2020 Jan 28. pii: 1078-0432.CCR-19-2576.
    PubMed     Abstract available

  12. ALVAREZ SECORD A, Bell Burdett K, Owzar K, Tritchler D, et al
    Predictive blood-based biomarkers in epithelial ovarian cancer patients treated with carboplatin and paclitaxel with or without bevacizumab: Results from GOG-0218.
    Clin Cancer Res. 2020 Jan 9. pii: 1078-0432.CCR-19-0226.
    PubMed     Abstract available

    December 2019
  13. LI F, Zhang Z, Cai J, Chen X, et al
    Primary preclinical and clinical Evaluation of 68Ga-DOTA-TMVP1 as a novel VEGFR-3 PET Imaging Radiotracer in Gynecological Cancer.
    Clin Cancer Res. 2019 Dec 16. pii: 1078-0432.CCR-19-1845.
    PubMed     Abstract available

  14. OZA AM, Matulonis UA, Alvarez Secord A, Nemunaitis J, et al
    A randomized phase 2 trial of epigenetic priming with guadecitabine and carboplatin in platinum-resistant, recurrent ovarian cancer.
    Clin Cancer Res. 2019 Dec 12. pii: 1078-0432.CCR-19-1638.
    PubMed     Abstract available

  15. HONG DS, Concin N, Vergote I, de Bono JS, et al
    Tisotumab Vedotin in Previously Treated Recurrent or Metastatic Cervical Cancer.
    Clin Cancer Res. 2019 Dec 3. pii: 1078-0432.CCR-19-2962.
    PubMed     Abstract available

  16. CROCE S, Lesluyes T, Valle C, M'Hamdi L, et al
    The NanoCind(R) signature is an independent prognosticator of recurrence and death in uterine leiomyosarcomas.
    Clin Cancer Res. 2019 Dec 3. pii: 1078-0432.CCR-19-2891.
    PubMed     Abstract available

    November 2019
  17. MADARIAGA A, Goodwin PJ, Oza AM
    Metformin in Gynecologic Cancers: Opening a New Window for Prevention and Treatment?
    Clin Cancer Res. 2019 Nov 26. pii: 1078-0432.CCR-19-3645.
    PubMed     Abstract available

    October 2019
  18. HANDLEY KF, Sood AK
    A solution to the dilution: The role for biomarkers in advanced ovarian cancer.
    Clin Cancer Res. 2019 Oct 31. pii: 1078-0432.CCR-19-3072.
    PubMed     Abstract available

  19. SOLIMAN PT, Westin SN, Iglesias DA, Fellman BM, et al
    Everolimus, letrozole, and metformin in women with advanced or recurrent endometrioid endometrial cancer: A multi-center, single arm, phase II study.
    Clin Cancer Res. 2019 Oct 18. pii: 1078-0432.CCR-19-0471.
    PubMed     Abstract available

  20. MCCLOSKEY CW, Cook DP, Kelly BS, Azzi F, et al
    Metformin abrogates age-associated ovarian fibrosis.
    Clin Cancer Res. 2019 Oct 9. pii: 1078-0432.CCR-19-0603.
    PubMed     Abstract available

    September 2019
  21. SHEE K, Wells JD, Ung M, Hampsch RA, et al
    A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition.
    Clin Cancer Res. 2019 Sep 26. pii: 1078-0432.CCR-18-2213.
    PubMed     Abstract available

  22. GERBER DE, Infante JR, Gordon MS, Goldberg SB, et al
    Phase Ia Study of Anti-NaPi2b Antibody-Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer Patients.
    Clin Cancer Res. 2019 Sep 20. pii: 1078-0432.CCR-18-3965.
    PubMed     Abstract available

  23. HEITZ F, Kommoss S, Tourani R, Grandelis A, et al
    Dilution of molecular-pathologic gene signatures by medically associated factors might prevent prediction of resection status after debulking surgery in patients with advanced ovarian cancer.
    Clin Cancer Res. 2019 Sep 16. pii: 1078-0432.CCR-19-1741.
    PubMed     Abstract available

  24. BONILLA L, Oza AM
    Targeting TGFbeta Pathway in Adult Granulosa Cell Tumor: Opening Pandora's Box?
    Clin Cancer Res. 2019;25:5432-5434.
    PubMed     Abstract available

  25. DE JONGE MM, Ritterhouse LL, de Kroon CD, Vreeswijk MPG, et al
    Germline BRCA-associated Endometrial Carcinoma is a Distinct Clinicopathologic Entity.
    Clin Cancer Res. 2019 Sep 6. pii: 1078-0432.CCR-19-0848.
    PubMed     Abstract available

  26. MAITLAND ML, O'Cearbhaill RE, Gobburu J
    Cancer Clinical Investigators Should Converge with Pharmacometricians.
    Clin Cancer Res. 2019;25:5182-5184.
    PubMed     Abstract available

    August 2019
  27. PARMAR K, Kochupurakkal BS, Lazaro JB, Wang ZC, et al
    The CHK1 Inhibitor Prexasertib Exhibits Monotherapy Activity in High-Grade Serous Ovarian Cancer Models and Sensitizes to PARP inhibition.
    Clin Cancer Res. 2019 Aug 13. pii: 1078-0432.CCR-19-0448.
    PubMed     Abstract available

  28. YANG H, Shu Z, Jiang Y, Mao W, et al
    6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers.
    Clin Cancer Res. 2019 Aug 7. pii: 1078-0432.CCR-18-3448.
    PubMed     Abstract available

    July 2019
  29. ISHAK CA, Lheureux S, De Carvalho DD
    DNA methylation as a robust classifier of epithelial ovarian cancer.
    Clin Cancer Res. 2019 Jul 23. pii: 1078-0432.CCR-19-1797.
    PubMed     Abstract available

  30. YEUNG TL, Leung CS, Yip KP, Sheng J, et al
    Anticancer immunotherapy by MFAP5 blockade inhibits fibrosis and enhances chemosensitivity in ovarian and pancreatic cancer.
    Clin Cancer Res. 2019 Jul 22. pii: 1078-0432.CCR-19-0187.
    PubMed     Abstract available

  31. TINKER AV, Hirte HW, Provencher DM, Butler MO, et al
    Dose-ranging and cohort-expansion study of monalizumab(IPH2201) in advanced gynecologic malignancies:A trial of the Canadian Cancer Trials Group (CCTG):IND221.
    Clin Cancer Res. 2019 Jul 15. pii: 1078-0432.CCR-19-0298.
    PubMed     Abstract available

  32. LI Z, Zhou W, Zhang Y, Sun W, et al
    ERK regulates HIF-1alpha-mediated platinum resistance by directly targeting PHD2 in ovarian cancer.
    Clin Cancer Res. 2019 Jul 8. pii: 1078-0432.CCR-18-4145.
    PubMed     Abstract available

    May 2019
  33. BODELON C, Killian JK, Sampson JN, Anderson WF, et al
    Molecular classification of epithelial ovarian cancer based on methylation profiling: evidence for survival heterogeneity.
    Clin Cancer Res. 2019 May 29. pii: 1078-0432.CCR-18-3720.
    PubMed     Abstract available

  34. BEAVER JA, Coleman RL, Arend RC, Armstrong DK, et al
    Advancing Drug Development in Gynecologic Malignancies.
    Clin Cancer Res. 2019 May 24. pii: 1078-0432.CCR-19-0619.
    PubMed     Abstract available

  35. HALDER J, Kamat AA, Landen CN Jr, Han LY, et al
    Correction: Focal Adhesion Kinase Targeting Using In vivo Short Interfering RNA Delivery in Neutral Liposomes for Ovarian Carcinoma Therapy.
    Clin Cancer Res. 2019;25:3194.

  36. FUCIKOVA J, Rakova J, Hensler M, Kasikova L, et al
    TIM-3 dictates functional orientation of the immune infiltrate in ovarian cancer.
    Clin Cancer Res. 2019 May 10. pii: 1078-0432.CCR-18-4175.
    PubMed     Abstract available

  37. TAO JJ, Cangemi NA, Makker V, Cadoo K, et al
    First-in-Human Phase I Study of the Activin A Inhibitor, STM 434, in Patients with Granulosa Cell Ovarian Cancer and Other Advanced Solid Tumors.
    Clin Cancer Res. 2019 May 8. pii: 1078-0432.CCR-19-1065.
    PubMed     Abstract available

    April 2019
  38. XING D, Zheng G, Pallavajjala A, Schoolmeester JK, et al
    Lineage-specific alterations in gynecologic neoplasms with choriocarcinomatous differentiation: implications for origin and therapeutics.
    Clin Cancer Res. 2019 Apr 22. pii: 1078-0432.CCR-18-4278.
    PubMed     Abstract available

  39. POSTOVIT LM, Dieters-Castator DZ, Rambau PF, Kelemen LE, et al
    Proteomics derived biomarker panel improves diagnostic precision to classify endometrioid and high-grade serous ovarian carcinoma.
    Clin Cancer Res. 2019 Apr 12. pii: 1078-0432.CCR-18-3818.
    PubMed     Abstract available

  40. KAWAKAMI E, Tabata J, Yanaihara N, Ishikawa T, et al
    Application of Artificial Intelligence for Preoperative Diagnostic and Prognostic Prediction in Epithelial Ovarian Cancer Based on Blood Biomarkers.
    Clin Cancer Res. 2019 Apr 11. pii: 1078-0432.CCR-18-3378.
    PubMed     Abstract available

  41. TAKENAKA M, Kobel M, Garsed DW, Fereday S, et al
    Survival Following Chemotherapy in Ovarian Clear Cell Carcinoma is Not Associated with Pathological Misclassification of Tumor Histotype.
    Clin Cancer Res. 2019 Apr 9. pii: 1078-0432.CCR-18-3691.
    PubMed     Abstract available

  42. COLOMBAN O, Tod M, Leary A, Ray-Coquard I, et al
    Early Modeled Longitudinal CA-125 Kinetics and Survival of Ovarian Cancer Patients: A GINECO AGO MRC CTU Study.
    Clin Cancer Res. 2019 Apr 1. pii: 1078-0432.CCR-18-3335.
    PubMed     Abstract available

    March 2019
  43. BYKOV Y, Zamarin D
    Virus, Vessel, Victory: A Novel Approach to Tumor Killing.
    Clin Cancer Res. 2019;25:1446-1448.
    PubMed     Abstract available

    January 2019
  44. MULLEN MM, Mutch DG
    Endometrial tumor immune response: predictive biomarker of response to immunotherapy.
    Clin Cancer Res. 2019 Jan 28. pii: 1078-0432.CCR-18-4122.
    PubMed     Abstract available

  45. GREENWOOD HE, McCormick PN, Gendron T, Glaser M, et al
    Measurement of tumor antioxidant capacity and prediction of chemotherapy resistance in preclinical models of ovarian cancer by positron emission tomography.
    Clin Cancer Res. 2019 Jan 16. pii: 1078-0432.CCR-18-3423.
    PubMed     Abstract available

  46. BINZER-PANCHAL A, Hardell E, Viklund B, Ghaderi M, et al
    Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.
    Clin Cancer Res. 2019 Jan 7. pii: 1078-0432.CCR-18-2792.
    PubMed     Abstract available

  47. SANTEGOETS SJ, van Ham VJ, Ehsan I, Charoentong P, et al
    The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival.
    Clin Cancer Res. 2019;25:240-252.
    PubMed     Abstract available

    December 2018
  48. BLAGDEN SP, Hamilton AL, Mileshkin L, Wong S, et al
    Phase IB Dose-Escalation and Expansion Study of AKT kinase inhibitor Afuresertib with Carboplatin and Paclitaxel in Recurrent Platinum-Resistant Ovarian Cancer.
    Clin Cancer Res. 2018 Dec 18. pii: 1078-0432.CCR-18-2277.
    PubMed     Abstract available

  49. KITSON S, Maskell Z, Sivalingam VN, Allen JL, et al
    PRE-surgical Metformin In Uterine Malignancy (PREMIUM): a multi-center, randomized double-blind, placebo-controlled phase 3 trial.
    Clin Cancer Res. 2018 Dec 18. pii: 1078-0432.CCR-18-3339.
    PubMed     Abstract available

  50. TALHOUK A, Derocher H, Schmidt P, Leung S, et al
    Molecular subtype not immune response drives outcomes in endometrial carcinoma.
    Clin Cancer Res. 2018 Dec 6. pii: 1078-0432.CCR-18-3241.
    PubMed     Abstract available

    November 2018
  51. HOLST F, Werner HMJ, Mjos S, Hoivik EA, et al
    PIK3CA Amplification Associates with Aggressive Phenotype but Not Markers of AKT-MTOR Signaling in Endometrial Carcinoma.
    Clin Cancer Res. 2018 Nov 15. pii: 1078-0432.CCR-18-0452.
    PubMed     Abstract available

  52. DE JONGE MM, Auguste A, van Wijk LM, Schouten PC, et al
    Frequent homologous recombination deficiency in high-grade endometrial carcinomas.
    Clin Cancer Res. 2018 Nov 9. pii: 1078-0432.CCR-18-1443.
    PubMed     Abstract available

    October 2018
  53. WU G, Cao L, Zhu J, Tan Z, et al
    Loss of RBMS3 Confers Platinum-resistance in Epithelial Ovarian Cancer via Activation of miR-126-5p/beta-catenin/CBP signaling.
    Clin Cancer Res. 2018 Oct 2. pii: 1078-0432.CCR-18-2554.
    PubMed     Abstract available

    September 2018
  54. MATUSZEWSKA K, Santry LA, Van Vloten JP, Au Yeung A, et al
    Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in Advanced Stage Ovarian Cancer.
    Clin Cancer Res. 2018 Sep 11. pii: 1078-0432.CCR-18-0220.
    PubMed     Abstract available

    August 2018
  55. LHEUREUX S, Tinker AV, Clarke BA, Ghatage P, et al
    A clinical and molecular Phase II trial of oral ENMD-2076 in ovarian clear cell carcinoma (OCCC): A study of the Princess Margaret Phase II Consortium.
    Clin Cancer Res. 2018 Aug 14. pii: 1078-0432.CCR-18-1244.
    PubMed     Abstract available

  56. PISANIC TR, Cope L, Lin SF, Yen TT, et al
    Methylomic analysis of ovarian cancers identifies tumor-specific alterations readily detectable in early precursor lesions.
    Clin Cancer Res. 2018 Aug 14. pii: 1078-0432.CCR-18-1199.
    PubMed     Abstract available

  57. SOUMERAI TE, Donoghue MTA, Bandlamudi C, Srinivasan P, et al
    Clin Cancer Res. 2018 Aug 1. pii: 1078-0432.CCR-18-0412.
    PubMed     Abstract available

    July 2018
  58. TOKER A, Nguyen LT, Stone SC, Yang C, et al
    Regulatory T cells in ovarian cancer are characterized by a highly activated phenotype distinct from that in melanoma.
    Clin Cancer Res. 2018 Jul 31. pii: 1078-0432.CCR-18-0554.
    PubMed     Abstract available

    Neoantigens in ovarian cancer: embarrassment of riches or needles in a haystack?
    Clin Cancer Res. 2018 Jul 6. pii: 1078-0432.CCR-18-1731.
    PubMed     Abstract available

  60. CHEN GM, Kannan L, Geistlinger L, Kofia V, et al
    Consensus on Molecular Subtypes of High-grade Serous Ovarian Carcinoma.
    Clin Cancer Res. 2018 Jul 3. pii: 1078-0432.CCR-18-0784.
    PubMed     Abstract available

  61. BLYUSS O, Burnell M, Ryan A, Gentry-Maharaj A, et al
    Comparison of longitudinal CA125 algorithms as a first line screen for ovarian cancer in the general population.
    Clin Cancer Res. 2018 Jul 3. pii: 1078-0432.CCR-18-0208.
    PubMed     Abstract available

  62. YANG H, Mao W, Rodriguez-Aguayo C, Mangala LS, et al
    Paclitaxel Sensitivity of Ovarian Cancer can be enhanced by knocking down Pairs of Kinases that regulate MAP4 Phosphorylation and Microtubule Stability.
    Clin Cancer Res. 2018 Jul 3. pii: 1078-0432.CCR-18-0504.
    PubMed     Abstract available

    June 2018
  63. SIMPKINS F, Jang K, Yoon H, Hew K, et al
    Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells.
    Clin Cancer Res. 2018 Jun 29. pii: 1078-0432.CCR-17-3697.
    PubMed     Abstract available

  64. LEE J, Chang CL, Lin JB, Wu MH, et al
    Skeletal Muscle Loss is an Imaging Biomarker of Outcome After Definitive Chemoradiotherapy for Locally Advanced Cervical Cancer.
    Clin Cancer Res. 2018 Jun 29. pii: 1078-0432.CCR-18-0788.
    PubMed     Abstract available

  65. BONAZZOLI E, Predolini F, Cocco E, Bellone S, et al
    Inhibition of BET bromodomain proteins with GS-5829 and GS-626510 in Uterine Serous Carcinoma, a biologically aggressive variant of Endometrial Cancer.
    Clin Cancer Res. 2018 Jun 25. pii: 1078-0432.CCR-18-0864.
    PubMed     Abstract available

    PARP inhibitors in ovarian cancer: a trailblazing and transformative journey.
    Clin Cancer Res. 2018 Jun 5. pii: 1078-0432.CCR-18-1314.
    PubMed     Abstract available

  67. TUMIATI M, Hietanen S, Hynninen J, Pietila E, et al
    A functional homologous recombination assay predicts primary chemotherapy response and long-term survival in ovarian cancer patients.
    Clin Cancer Res. 2018 Jun 1. pii: 1078-0432.CCR-17-3770.
    PubMed     Abstract available

    May 2018
  68. DENIGER DC, Pasetto A, Robbins PF, Gartner JJ, et al
    T-cell responses to TP53 "hotspot" mutations and unique neoantigens expressed by human ovarian cancers.
    Clin Cancer Res. 2018 May 31. pii: 1078-0432.CCR-18-0573.
    PubMed     Abstract available

  69. GRISHAM R, Moore KN, Gordon MS, Harb W, et al
    Phase Ib Study of Binimetinib with Paclitaxel in Patients with Platinum-Resistant Ovarian Cancer: Final Results, Potential Biomarkers, and Extreme Responders.
    Clin Cancer Res. 2018 May 29. pii: 1078-0432.CCR-18-0494.
    PubMed     Abstract available

  70. UUSI-KERTTULA H, Davies JA, Thompson J, Wongthida P, et al
    Ad5NULL-A20 - a tropism-modified, alphavbeta6 integrin-selective oncolytic adenovirus for epithelial ovarian cancer therapies.
    Clin Cancer Res. 2018 May 24. pii: 1078-0432.CCR-18-1089.
    PubMed     Abstract available

  71. SASANO T, Mabuchi S, Kozasa K, Kuroda H, et al
    The highly metastatic nature of uterine cervical/endometrial cancer displaying tumor-related leukocytosis: clinical and preclinical investigations.
    Clin Cancer Res. 2018 May 11. pii: 1078-0432.CCR-17-2472.
    PubMed     Abstract available

  72. MATSUDA T, Leisegang M, Park JH, Ren L, et al
    Induction of Neoantigen-specific Cytotoxic T Cells and Construction of T-cell Receptor-engineered T cells for Ovarian Cancer.
    Clin Cancer Res. 2018 May 2. pii: 1078-0432.CCR-18-0142.
    PubMed     Abstract available

    April 2018
  73. CAUMANNS JJ, Berns K, Wisman GBA, Fehrmann RSN, et al
    Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.
    Clin Cancer Res. 2018 Apr 23. pii: 1078-0432.CCR-17-3060.
    PubMed     Abstract available

  74. DI LJ, Hao D, Liu J, Chen M, et al
    Immunogenomic analyses of advanced serous ovarian cancer reveal immune score is a strong prognostic factor and an indicator of chemo-sensitivity.
    Clin Cancer Res. 2018 Apr 16. pii: 1078-0432.CCR-17-3862.
    PubMed     Abstract available

  75. BELUR NAGARAJ A, Kovalenko O, Avelar RA, Joseph P, et al
    Mitotic Exit dysfunction through the deregulation of APC/C characterizes cisplatin resistant state in epithelial ovarian cancer.
    Clin Cancer Res. 2018 Apr 13. pii: 1078-0432.CCR-17-2885.
    PubMed     Abstract available

  76. ISON G, Howie LJ, Amiri-Kordestani L, Zhang L, et al
    FDA Approval Summary: Niraparib for the maintenance treatment of patients with recurrent ovarian cancer in response to platinum-based chemotherapy.
    Clin Cancer Res. 2018 Apr 12. pii: 1078-0432.CCR-18-0042.
    PubMed     Abstract available

  77. PULLIAM N, Fang F, Ozes AR, Tang J, et al
    An Effective Epigenetic-PARP inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA-mutations.
    Clin Cancer Res. 2018 Apr 3. pii: 1078-0432.CCR-18-0204.
    PubMed     Abstract available

    March 2018
  78. ZHU H, Gu X, Xia L, Zhou Y, et al
    A Novel TGF-beta Trap Blocks Chemotherapeutics-Induced TGF-beta1 Signaling and Enhances Their Anticancer Activity in Gynecological Cancers.
    Clin Cancer Res. 2018 Mar 16. pii: 1078-0432.CCR-17-3112.
    PubMed     Abstract available

  79. KALLI KR, Block MS, Kasi PM, Erskine CL, et al
    Folate Receptor Alpha Peptide Vaccine generates immunity in Breast and Ovarian Cancer Patients.
    Clin Cancer Res. 2018 Mar 15. pii: 1078-0432.CCR-17-2499.
    PubMed     Abstract available

  80. MATEI D, Ghamande S, Roman LD, Alvarez Secord A, et al
    A Phase 1 Clinical Trial of Guadecitabine and Carboplatin In Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic And Pharmacodynamic Analyses.
    Clin Cancer Res. 2018 Mar 2. pii: 1078-0432.CCR-17-3055.
    PubMed     Abstract available

    February 2018
  81. HUANG YF, Wu YH, Cheng WF, Peng SL, et al
    Vitamin D-Binding Protein Enhances Epithelial Ovarian Cancer Progression by Regulating the Insulin-like Growth Factor-1/Akt Pathway and Vitamin D Receptor Transcription.
    Clin Cancer Res. 2018 Feb 23. pii: 1078-0432.CCR-17-2943.
    PubMed     Abstract available

  82. LANG JD, Hendricks WPD, Orlando KA, Yin H, et al
    Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multi-kinase inhibition.
    Clin Cancer Res. 2018 Feb 9. pii: 1078-0432.CCR-17-1928.
    PubMed     Abstract available

  83. SHAH A, Bloomquist E, Tang S, Fu W, et al
    FDA Approval: Ribociclib for the Treatment of Postmenopausal Women with Hormone Receptor-Positive, HER2-Negative Advanced or Metastatic Breast Cancer.
    Clin Cancer Res. 2018 Feb 7. pii: 1078-0432.CCR-17-2369.
    PubMed     Abstract available

    January 2018
  84. BELLONE S, Buza N, Choi J, Zammataro L, et al
    Exceptional response to pembrolizumab in a metastatic, chemotherapy/radiation resistant ovarian cancer patient harboring a CD274/PD-L1-genetic rearrangement.
    Clin Cancer Res. 2018 Jan 19. pii: 1078-0432.CCR-17-1805.
    PubMed     Abstract available

  85. HARDWICK NR, Frankel P, Ruel C, Kilpatrick J, et al
    p53-reactive T cells are associated with clinical benefit in patients with platinum-resistant epithelial ovarian cancer after treatment with a p53 vaccine and gemcitabine chemotherapy.
    Clin Cancer Res. 2018 Jan 4. pii: 1078-0432.CCR-17-2709.
    PubMed     Abstract available

    December 2017
  86. TUCKER DW, Getchell CR, McCarthy ET, Ohman AW, et al
    Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer.
    Clin Cancer Res. 2017 Dec 20. pii: 1078-0432.CCR-17-1958.
    PubMed     Abstract available

    November 2017
  87. NORQUIST BM, Brady MF, Harrell MI, Walsh T, et al
    Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: an NRG Oncology/Gynecologic Oncology Group Study.
    Clin Cancer Res. 2017 Nov 30. pii: 1078-0432.CCR-17-1327.
    PubMed     Abstract available

  88. PENG G, Mills GB
    Surviving ovarian cancer: an affair between defective DNA repair and RB1.
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